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Lumbar nerves

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https://www.readbyqxmd.com/read/29236218/the-dangers-of-the-head-down-position-in-patients-with-untreated-pituitary-macroadenomas-case-series-and-review-of-literature
#1
Satoshi Kiyofuji, Avital Perry, Christopher S Graffeo, Caterina Giannini, Michael J Link
PURPOSE: Cavernous sinus syndrome is a rare phenomenon, characterized by simultaneous neuropathies of cranial nerves III-VI. Various pathological processes have been reported as precipitating etiologies, including infection, inflammation, vascular lesions, and neoplasms. PURPOSE: We report a unique case series of cavernous sinus syndrome attributable to prolonged Trendelenburg or prone positioning during non-cranial procedures and review the pertinent literature to enlighten on this rare but catastrophic phenomenon...
December 13, 2017: Pituitary
https://www.readbyqxmd.com/read/29233749/an-amendment-to-the-neidre-and-macnab-classification-system-for-lumbosacral-nerve-root-anomaly-and-its-implication-in-percutaneous-endoscopic-lumbar-discectomy
#2
Chen Yu, Chang Zhengqi, Yu Xiuchun
BACKGROUND: Lumbar disc herniation complicated with nerve root anomaly presents great challenges to diagnosis and treatment, improper selection of surgical procedures may cause inferior outcomes and neurological injury. CASE DESCRIPTION: A 66-year old male presented with low back pain and radicular symptoms involving bilateral L-5 and S-1 nerve roots. Instead of percutaneous endoscopic lumbar discectomy, aggressive decompression was carried out due to deviation between examination and imaging findings...
December 9, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29231338/-the-third-lumbar-transverse-process-syndrome-treated-with-acupuncture-at-zygapophyseal-joint-and-transverse-process-a-randomized-controlled-trial
#3
Fangling Li, Dingyan Bi
OBJECTIVE: To explore the effects differences for the third lumbar transverse process syndrome between acupuncture mainly at zygapophyseal joint and transverse process and conventional acupuncture. METHODS: Eighty cases were randomly assigned into an observation group and a control group, 40 cases in each one. In the observation group, patients were treated with acupuncture at zygapophyseal joint, transverse process, the superior gluteus nerve into the hip point and Weizhong (BL 40), and those in the control group were treated with acupuncture at Qihaishu (BL 24), Jiaji (EX-B 2) of L2-L4, the superior gluteus nerve into the hip point and Weizhong (BL 40)...
August 12, 2017: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
https://www.readbyqxmd.com/read/29231159/facet-joint-injections-for-non-specific-low-back-pain-a-feasibility-rct
#4
Saowarat Snidvongs, Rod S Taylor, Alia Ahmad, Simon Thomson, Manohar Sharma, Angela Farr, Deborah Fitzsimmons, Stephanie Poulton, Vivek Mehta, Richard Langford
BACKGROUND: Pain of lumbar facet-joint origin is a common cause of low back pain in adults and may lead to chronic pain and disability, with associated health and socioeconomic implications. The socioeconomic burden includes an inability to return to work resulting in loss of productivity in addition to direct and indirect health-care utilisation costs. Lumbar facet-joints are paired synovial joints between the superior and inferior articular processes of consecutive lumbar vertebrae and between the fifth lumbar vertebra and the sacrum...
December 2017: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/29230542/secondary-intracranial-hypertension-pseudotumor-cerebri-presenting-as-post-traumatic-headache-in-mild-traumatic-brain-injury-a-case-series
#5
Tonia Sabo, Charlene Supnet, Sushmita Purkayastha
BACKGROUND: Cerebral edema peaks 36-72 h after moderate traumatic brain injury but thought to be uncommon after mild traumatic brain injury. Post-traumatic headache can develop 48-72 h post-injury, perhaps reflecting the developing cerebral edema. Pseudotumor cerebri can result from various causes, including cerebral edema, and is characterized by increased intracranial pressure, headache, visual, and other common symptoms. Our objective was to report a phenotypically identifiable post-traumatic headache subtype...
December 11, 2017: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/29224922/neurons-and-satellite-glial-cells-in-adult-rat-lumbar-dorsal-root-ganglia-express-connexin-36
#6
E Martha Pérez Armendariz, Monica Norcini, Beatriz Hernández-Tellez, Andrés Castell-Rodríguez, Cristina Coronel-Cruz, Raquel Guerrero Alquicira, Alexandra Sideris, Esperanza Recio-Pinto
Previous studies have shown that following peripheral nerve injury there was a downregulation of the gap junction protein connexin 36 (Cx36) in the spinal cord; however, it is not known whether Cx36 protein is expressed in the dorsal root ganglia (DRGs), nor if its levels are altered following peripheral nerve injuries. Here we address these aspects in the adult rat lumbar DRG. Cx36 mRNA was detected using qRT-PCR, and Cx36 protein was identified in DRG sections using immunohistochemistry (IHC) and immunofluorescence (IF)...
December 7, 2017: Acta Histochemica
https://www.readbyqxmd.com/read/29224279/-overexpression-of-trpv1-after-periphery-nerve-injury-attenuates-nerve-regeneration-in-rats
#7
J Bai, Y Zhang, Y F Wang, J Lan, X Q Li
Objective: To observe the effect of the expressive or functional blockage of TRPV1 on nerve regeneration after sciatic trans-section injury. Methods: AMG-517, a kind of TRPV1 inhibitor, was injected into the surrounding area of the ipsilateral lumbar dorsal root ganglia while unilateral sciatic nerve was transected. A total of 24 healthy male Sprague-Dawley rats were divided into 4 groups: control group, injury only group, injury+ AMG-517 150 μg/kg group, injury+ AMG-517 300 μg/kg group. The injury only group was injected the same volume of medium...
December 8, 2017: Zhonghua Bing Li Xue za Zhi Chinese Journal of Pathology
https://www.readbyqxmd.com/read/29223694/atraumatic-versus-conventional-lumbar-puncture-needles-a-systematic-review-and-meta-analysis
#8
Siddharth Nath, Alex Koziarz, Jetan H Badhiwala, Waleed Alhazzani, Roman Jaeschke, Sunjay Sharma, Laura Banfield, Ashkan Shoamanesh, Sheila Singh, Farshad Nassiri, Wieslaw Oczkowski, Emilie Belley-Côté, Ray Truant, Kesava Reddy, Maureen O Meade, Forough Farrokhyar, Malgorzata M Bala, Fayez Alshamsi, Mette Krag, Itziar Etxeandia-Ikobaltzeta, Regina Kunz, Osamu Nishida, Charles Matouk, Magdy Selim, Andrew Rhodes, Gregory Hawryluk, Saleh A Almenawer
BACKGROUND: Atraumatic needles have been proposed to lower complication rates after lumbar puncture. However, several surveys indicate that clinical adoption of these needles remains poor. We did a systematic review and meta-analysis to compare patient outcomes after lumbar puncture with atraumatic needles and conventional needles. METHODS: In this systematic review and meta-analysis, we independently searched 13 databases with no language restrictions from inception to Aug 15, 2017, for randomised controlled trials comparing the use of atraumatic needles and conventional needles for any lumbar puncture indication...
December 6, 2017: Lancet
https://www.readbyqxmd.com/read/29218390/gemelli-obturator-complex-in-the-deep-gluteal-space-an-anatomic-and-dynamic-study
#9
Ramon Balius, Antonio Susín, Carles Morros, Montse Pujol, Dolores Pérez-Cuenca, Xavier Sala-Blanch
OBJECTIVE: To investigate the behavior of the sciatic nerve during hip rotation at subgluteal space. MATERIALS AND METHODS: Sonographic examination (high-resolution ultrasound machine at 5.0-14 MHZ) of the gemelli-obturator internus complex following two approaches: (1) a study on cadavers and (2) a study on healthy volunteers. The cadavers were examined in pronation, pelvis-fixed position by forcing internal and external rotations of the hip with the knee in 90° flexion...
December 7, 2017: Skeletal Radiology
https://www.readbyqxmd.com/read/29200998/attenuation-of-the-infiltration-of-angiotensin-ii-expressing-cd3-t-cells-and-the-modulation-of-nerve-growth-factor-in-lumbar-dorsal-root-ganglia-a-possible-mechanism-underpinning-analgesia-produced-by-ema300-an-angiotensin-ii-type-2-at2-receptor-antagonist
#10
Nemat Khan, Arjun Muralidharan, Maree T Smith
Recent preclinical and proof-of-concept clinical studies have shown promising analgesic efficacy of selective small molecule angiotensin II type 2 (AT2) receptor antagonists in the alleviation of peripheral neuropathic pain. However, their cellular and molecular mechanism of action requires further investigation. To address this issue, groups of adult male Sprague-Dawley rats with fully developed unilateral hindpaw hypersensitivity, following chronic constriction injury (CCI) of the sciatic nerve, received a single intraperitoneal bolus dose of the small molecule AT2 receptor antagonist, EMA300 (10 mg kg-1), or vehicle...
2017: Frontiers in Molecular Neuroscience
https://www.readbyqxmd.com/read/29196027/cancer-chemotherapy-in-early-life-significantly-alters-the-maturation-of-pain-processing
#11
G J Hathway, Emily Murphy, Joseph Lloyd, Charles Greenspon, R P Hulse
Advances in paediatric cancer treatment have led to a ten year survival rate greater than 75%. Platinum-based chemotherapies (e.g.cisplatin) induce peripheral sensory neuropathy in adult and paedriatric cancer patients. The period from birth through to adulthood represents a period of maturation within nociceptive systems. Here we investigated how cisplatin impacts upon postnatal maturation of nociceptive systems. Neonatal Wistar rats (Postnatal day (P) 7) were injected (i.p.) daily with either vehicle (PBS) or cisplatin (1mg/kg) for five consecutive days...
November 28, 2017: Neuroscience
https://www.readbyqxmd.com/read/29190962/wu-tou-decoction-attenuates-neuropathic-pain-via-suppressing-spinal-astrocytic-il-1r1-traf6-jnk-signaling
#12
Chao Wang, Xiangying Kong, Chunyan Zhu, Chunfang Liu, Danni Sun, Qionghong Xu, Zhiyun Mao, Qingxia Qin, Hongchang Su, Danqiao Wang, Xiaoliang Zhao, Na Lin
Neuropathic pain (NP) caused by nerve injuries continues to be an intractable challenge due to inadequate therapeutic strategies. Recent study demonstrated glia-induced neuro-inflammation in the spinal cord, especially the activation of astrocytes, plays an essential role in the development of NP, which opens new avenues for NP treatment. In this study, we explored the anti-hyperalgesia properties of Wu-tou decoction (WTD) and showed that WTD potently attenuates mechanical allodynia and heat hyperalgesia in lumbar 5 (L5) spinal nerve ligation (SNL)-induced NP without noticeable side effect or affecting basal pain perception of mice...
November 3, 2017: Oncotarget
https://www.readbyqxmd.com/read/29184272/approach-to-chronic-secondary-headache-a-case-report-on-unusual-drug-side-effects
#13
Hamid Reza Riasi, Forod Salehi, Morteza Hajihosseini
In this article, we present the case of a 12-year-old female child who complained of bilateral temporal and frontal headache for 2 to 3 months with nausea and vomiting. Physical examination revealed right-sided sixth cranial nerve palsy and papilledema in ophthalmoscopy. To find the cause of increased intracranial pressure, the patient underwent brain imaging and brain MRI showed no abnormality. Ultimately, lumbar puncture (LP) was performed and cerebrospinal fluid (CSF) pressure was 280 mmH2O with normal chemistry...
November 2017: Iranian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29182113/fusion-segment-of-high-grade-lumbar-spondylolisthesis-2-year-follow-up
#14
X Li, L Xu, Q Kong
The clinical efficacy of reduction and fusion surgery and the suitable range of fusion-segment were evaluated in 12 pediatric patients treated for high-grade spondylolisthesis. Pre/post-operative clinical and radiological assessments were analyzed. A transient L5 nerve root paralysis was observed in one patient with L5 spondylolisthesis. No degenerative spondylolisthesis or adjacent segmental instability occurred above the fusion segments. In conclusion, we suggest that, in case of spondylolisthesis without severe structural scoliosis deformity or only associated with lumbosacral deformity, the posterior ligament complex should be protected in case of adjacent segmental instability and spondylolisthesis...
December 2016: Acta Orthopaedica Belgica
https://www.readbyqxmd.com/read/29179284/-analysis-of-correlation-between-spinal-nerve-high-tension-and-disc-degeneration-in-100-cases
#15
Q J Kong, X M Xu, J C Sun, Y Wang, G D Shi, Y F Guo, H S Yang, Y Yang, J G Shi
Objective: To explore the correlation between the spinal nerve high tension and lumbar disc degeneration, the pathogenesis of hanging intervertebral disc degeneration. Methods: From June 2016 to June , a retrospective analysis 2017 of 100 cases of lumbar spinal stenosis were included in Department of Spine Surgery, Changzheng Hospital, the Second Military Medical University. They were divided into experimental group (50 cases, nerve high tension group) and control group (50 cases, nervous tension in the normal group) according to preoperative lumbar MRI of cauda equina syndrome and settlement of intraoperative detecting nerve tension...
November 21, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/29178917/the-influence-of-surface-emg-triggered-multichannel-electrical-stimulation-on-sensomotoric-recovery-in-patients-with-lumbar-disc-herniation-study-protocol-for-a-randomized-controlled-trial-reco
#16
Sara Lener, Christoph Wipplinger, Sebastian Hartmann, Wolfgang N Löscher, Sabrina Neururer, Matthias Wildauer, Claudius Thomé, Anja Tschugg
BACKGROUND: Intervertebral disc degeneration is one of the most common reasons for chronic low back pain and sensomotoric deficits, often treated by lumbar sequestrectomy. Nevertheless, the prognostic factors relevant for time and quality of recovery, of the surgical procedure, relative to conservative treatment, remain controversial and require further investigation. Surface electrical stimulation (SES) may be an influential intervention, already showing positive impact on motor and sensory recovery in different patient groups...
November 25, 2017: Trials
https://www.readbyqxmd.com/read/29178281/abdominal-girth-and-dorso-sacral-distance-can-be-used-to-estimate-lumbosacral-cerebral-fluid-volume
#17
Q H Zhou, C Shen, G Chen
BACKGROUND: Patients' abdominal girth and vertebral column length are highly correlated with the spread of local anaesthetics after spinal anaesthesia. Lumbosacral cerebrospinal fluid volume is the primary determinant for spinal spread. Thus, we attempted to verify the hypothesis that abdominal girth and dorso-sacral distance are correlated with lumbosacral cerebrospinal fluid volume. METHODS: Forty-five healthy volunteers were enrolled in this study to measure lumbosacral cerebrospinal fluid volume using magnetic resonance imaging...
November 27, 2017: Acta Anaesthesiologica Scandinavica
https://www.readbyqxmd.com/read/29177411/ultrasmall-superparamagnetic-iron-oxide-imaging-identifies-tissue-and-nerve-inflammation-in-pain-conditions
#18
Shiqian Shen, Weihua Ding, Shihab Ahmed, Ranliang Hu, Arissa Opalacz, Sarah Roth, Zerong You, Gregory R Wotjkiewicz, Grewo Lim, Lucy Chen, Jianren Mao, John W Chen, Yi Zhang
Objective: Correlation between radiologic structural abnormalities and clinical symptoms in low back pain patients is poor. There is an unmet clinical need to image inflammation in pain conditions to aid diagnosis and guide treatment. Ferumoxytol, an ultrasmall superparamagnetic iron oxide (USPIO) nanoparticle, is clinically used to treat iron deficiency anemia and showed promise in imaging tissue inflammation in human. We explored whether ferumoxytol can be used to identify tissue and nerve inflammation in pain conditions in animals and humans...
November 21, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/29174424/hemi-arthroplasty-performed-in-a-109-year-old-patient-with-intertrochanteric-fracture-a-case-report
#19
Peng-Fei Yang, Hao Chen, Xiao-Jun Duan, Guang-Xing Chen, Lin Guo, Hua-Quan Fan, Liu Yang
The mortality of conservative treatment and the risk resulting from operation for elderly patients with femoral intertrochanteric fractures are high. Safety in the perioperative period and quicker recovery should be placed at the top priority for elderly patients with hip fractures. We reported a case of 109-year-old female patient with intertrochanteric fracture who has undergone the hemiarthroplasty in our center recently. With sciatic nerve and lateral cutaneous nerve block anesthesia, she was offered the artificial femoral head replacement in the lumbar plexus block after sufficient preoperative preparation...
November 4, 2017: Chinese Journal of Traumatology, Zhonghua Chuang Shang za Zhi
https://www.readbyqxmd.com/read/29174073/lumbar-medial-branch-block-volume-dependent-dispersion-patterns-as-a-predictor-for-ablation-success-a-cadaveric-study
#20
Sayed E Wahezi, Edward Alexeev, John S Georgy, Nogah Haramati, Stephen A Erosa, Jay M Shah, Sherry Downie
BACKGROUND: Lumbar facet arthropathy is a common cause of low back pain. Literature supports treatment with radiofrequency ablation (RFA) of associated nerves that innervate lumbar facets when alternative conservative therapies have failed. Diagnostic local anesthetic blocks precede therapeutic ablation, but have a false positive rate of 27-63%, and some have questioned their utility in predicting therapeutic response to RFA. The authors believe that injectate volume may be a contributing factor to false positivity...
November 22, 2017: PM & R: the Journal of Injury, Function, and Rehabilitation
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