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https://www.readbyqxmd.com/read/29935323/orbital-infarction-syndrome-following-mechanical-thrombectomy-secondary-to-embolization-in-new-territory
#1
Waleed Brinjikji, Patrick J Nicholson, Christopher A Hilditch, Anderson Chun On Tsang, Timo Krings
BACKGROUND: Orbital infarction syndrome (OIS) is a rare entity defined as ischemia of all intraorbital and intra-occular structures including the optic nerve, extraocular muscles and orbital fat. This entity is rare due to rich anastomotic orbital vascularization from both the internal carotid artery and external carotid artery. We report a case of a patient who suffered ENT to the ophthalmic artery and external carotid artery which resulted in orbital infarction syndrome and describe techniques to avoid such complications...
June 20, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29935198/refinement-of-embolic-stroke-model-in-rats-effect-of-post-embolization-anesthesia-duration-on-arterial-blood-pressure-cerebral-edema-and-mortality
#2
Bryan T C Chuang, Xiaoguang Liu, Alexander J Lundberg, Tommy J K Toung, John A Ulatowski, Raymond C Koehler
BACKGROUND: Injection of a clot into the internal carotid artery is an experimental model of ischemic stroke that is considered to closely mimic embolic stroke in humans. In this model, the common carotid artery typically remains temporarily occluded to permit time for stabilization of the clot in the middle cerebral artery. However, the associated lengthening of the anesthesia duration could affect arterial blood pressure and stroke outcome. NEW METHOD: We refined the model by examining how increasing isoflurane anesthesia duration from 30 to 60 min after clot embolization affects mortality, infarct volume, edema, blood-brain barrier permeability, and the 8-h post-ischemic time course of blood pressure, which has not been reported previously in this model...
June 20, 2018: Journal of Neuroscience Methods
https://www.readbyqxmd.com/read/29934262/how-to-perform-microscopic-endoscopic-resection-of-large-petrous-apex-lesions
#3
V Patron, M Humbert, E Micault, E Emery, M Hitier
The endoscope and microscope can be used conjointly in certain sites, such as middle ear cholesteatoma or for resection of cerebellopontine angle tumours. Petrous apex tumours are classically accessed via a lateral otological approach, or, for the most anterior tumours, via an endonasal endoscopic approach. Surgical access via a lateral incision is limited inferiorly by the superior bulb of the internal jugular vein, medially by the labyrinth, facial nerve and internal auditory canal, superiorly by the dura mater, and laterally by the internal carotid artery...
June 19, 2018: European Annals of Otorhinolaryngology, Head and Neck Diseases
https://www.readbyqxmd.com/read/29933009/roflumilast-promotes-memory-recovery-and-attenuates-white-matter-injury-in-aged-rats-subjected-to-chronic-cerebral-hypoperfusion
#4
Amanda Santiago, Lígia Mendes Soares, Melissa Schepers, Humberto Milani, Tim Vanmierlo, Jos Prickaerts, Rúbia M Weffort de Oliveira
Chronic cerebral hypoperfusion (CCH) has been associated with aging-related vascular dementia, including Alzheimer's disease. It can be induced by the four-vessel occlusion/internal carotid artery (4VO/ICA) model in aged rats, resulting in persistent memory deficits, white matter injury, and significant neuronal loss in the hippocampus and cerebral cortex. The phosphodiesterase type 4 inhibitor (PDE4-I) roflumilast has been reported to have pro-cognitive effects in several behavioral paradigms. The present study evaluated the effects of repeated roflumilast treatment in aged rats that were subjected to CCH...
June 19, 2018: Neuropharmacology
https://www.readbyqxmd.com/read/29932381/endoscope-assisted-contralateral-transmaxillary-approach-to-the-clivus-and-the-hypoglossal-canal-technical-case-report
#5
Eva Pamias-Portalatin, Deependra Mahato, Jordina Rincon-Torroella, Tito Vivas-Buitrago, Alfredo Quiñones-Hinojosa, Kofi O Boahene
Clival lesions are still considered surgically complex due to their anatomical location. Critical structures, such as the internal carotid arteries (ICAs), cavernous sinuses, cranial nerves, and brainstem, may be encased within the lesion. Although advances in endoscopic endonasal approaches have provided new routes to these lesions, exposure and resection of clival tumors through the endonasal route remain a technical challenge. Here, the authors report a left-sided endoscopic transmaxillary approach to access the right aspect of the clivus and the hypoglossal canal...
June 22, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29932380/comparison-of-flow-diversion-with-clipping-and-coiling-for-the-treatment-of-paraclinoid-aneurysms-in-115-patients
#6
Michael A Silva, Alfred P See, Priyank Khandelwal, Ashutosh Mahapatra, Kai U Frerichs, Rose Du, Nirav J Patel, Mohammad A Aziz-Sultan
OBJECTIVE Paraclinoid aneurysms represent approximately 5% of intracranial aneurysms (Drake et al. [1968]). Visual impairment, which occurs in 16%-40% of patients, is among the most common presentations of these aneurysms (Day [1990], Lai and Morgan [2013], Sahlein et al. [2015], and Silva et al. [2017]). Flow-diverting stents, such as the Pipeline Embolization Device (PED), are increasingly used to treat these aneurysms, in part because of their theoretical reduction of mass effect (Fiorella et al. [2009])...
June 22, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29932366/hybrid-vascular-intervention-for-a-giant-cervical-carotid-artery-aneurysm-in-a-clopidogrel-hyporesponsive-child
#7
Osman Ocal, Mustafa Yilmaz, Bora Peynircioglu, Burcak Bilginer, Ahmet Peker, Anil Arat
Aneurysms of the extracranial internal carotid artery (ICA) in pediatric patients are rare and mostly treated surgically. The authors present the case of a child with a giant extracranial ICA aneurysm presenting with gradual airway compression. A plan was made to explore the aneurysm surgically and straighten the associated carotid artery kinks during the operation to enable further endovascular treatment if primary reconstruction of the carotid artery proved not to be possible. Finally, the aneurysm was successfully treated with staged hybrid intervention, which consisted of surgical correction of parent artery kinks followed by endovascular implantation of stent grafts...
June 22, 2018: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/29930871/stenotic-changes-of-the-posterior-cerebral-artery-are-a-major-contributing-factor-for-cerebral-infarction-in-moyamoya-disease
#8
Akira Ohkura, Tetsuya Negoto, Takachika Aoki, Kei Noguchi, Yuji Okamoto, Hideki Komatani, Takayuki Kawano, Akitake Mukasa, Motohiro Morioka
Background: Some patients with moyamoya disease (MMD) show broad infarction with moderate internal carotid artery (ICA) stenosis, whereas others with complete ICA occlusion show no infarction. This suggests that other factors contribute to the occurrence of infarction. Contributing factors predictive of cerebral infarcts must be identified for the prevention of infarction and the consequent neurological deficits. Methods: We examined data from 93 patients with confirmed MMD for the presence of infarction ( n = 72), transient ischemic attack (TIA, n = 41), asymptomatic presentation ( n = 51), or hemorrhage ( n = 22) in 186 bilateral cerebral hemispheres...
2018: Surgical Neurology International
https://www.readbyqxmd.com/read/29930744/optimization-of-cervical-lymph-node-clinical-target-volume-delineation-in-nasopharyngeal-carcinoma-a-single-center-experience-and-recommendation
#9
Li Li, Yi Li, Jun Zhang, Qiuji Wu, Haijun Yu, Zheng Li, Conghua Xie, Yunfeng Zhou, Yahua Zhong
Nasopharyngeal carcinoma (NPC) are characterized by distinct lymph node metastasis patterns. In order to minimize cervical lymph node irradiation volume, 379 NPC patients with metastatic cervical lymph nodes were eligible for geographic mapping. All lymph nodes were mapped into simulation computed tomography images of a template lymph node negative patient. The proportions of retropharyngeal lymph nodes (RLNs), Level Ib, II, III, IV, Va, Vb and supraclavicular (SCV) lymph nodes were 6.9%, 0.5%, 55.25%, 20.4%, 8...
June 5, 2018: Oncotarget
https://www.readbyqxmd.com/read/29930210/-unruptured-arteriosclerotic-aneurysm-in-the-distal-middle-cerebral-artery-a-case-report
#10
Takayuki Anno, Nobuyuki Kobayashi, Takehiko Yamaguchi
We report a rare case of an unruptured cerebral aneurysm in the left distal middle cerebral artery(MCA). A 76-year-old woman was referred to our department for unruptured cerebral aneurysms detected incidentally by magnetic resonance angiography. A left carotid angiogram revealed a saccular aneurysm arising in an arterial trunk unrelated to the branching zone of the distal MCA. The patient underwent an operation for trapping and excision of the saccular aneurysm in the distal MCA followed by end-to-end anastomosis...
June 2018: No Shinkei Geka. Neurological Surgery
https://www.readbyqxmd.com/read/29928605/hemodynamic-analysis-of-carotid-artery-after-endarterectomy-a-preliminary-and-quantitative-imaging-study-based-on-computational-fluid-dynamics-and-magnetic-resonance-angiography
#11
Yuanyuan Dai, Peng Lv, Ashkan Javadzadegan, Xiao Tang, Yi Qian, Jiang Lin
Background: The carotid blood flow following carotid endarterectomy (CEA) is not fully understood. Computational fluid dynamics (CFD) is a promising method to study blood flow. This study is to investigate local hemodynamic characteristics after CEA via the use of unenhanced magnetic resonance angiography (MRA) and CFD. Methods: Eight carotid arteries with atherosclerosis and sixteen normal carotid arteries were included in this study. Time-of-flight (TOF) and phase contrast (PC) MRA were applied for the measurement of three-dimensional artery geometries and velocity profile under CFD simulation...
May 2018: Quantitative Imaging in Medicine and Surgery
https://www.readbyqxmd.com/read/29927399/-cerebral-atherosclerosis-a-biomarker-profile
#12
M M Tanashyan, O V Lagoda, A N Evdokimenko, A A Shabalina, A A Raskurazhev
AIM: To assess the changes in several biomarkers in patients with atherosclerosis of brachiocephalic arteries and shape a biomarker profile of cerebral atherosclerosis as an integrative index. MATERIAL AND METHODS: The study included 124 patients with atherosclerotic lesions of internal carotid arteries (82 men and 42 women) aged from 37 to 73 years. The patients were stratified by history of prior stroke into 'asymptomatic' and 'symptomatic'. Along with general clinical and neurological examinations, ultrasound analysis of brachiocephalic arteries, neuroimaging, identification of biomarkers reflecting different stages of atherogenesis and evaluation of pathomorphological parameters of atherosclerotic plaques removed during carotid endarterectomy surgery were performed...
2018: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/29925330/features-of-branch-occlusive-disease-type-intracranial-atherosclerotic-stroke-in-young-patients
#13
Zhang-Ning Zhao, Xiao-Lin Li, Jin-Zhi Liu, Zhi-Ming Jiang, Ai-Hua Wang
BACKGROUND: Young ischemic stroke patients are common while classification and analysis based upon imaging characteristics are rarely reported. We intend to compare the clinical and MRI characteristics of cerebral stroke induced by intracranial atherosclerosis between young patients with branch occlusive disease (BOD) and those with non-branch occlusive disease (non-BOD) or small artery disease (SAD). METHODS: A total of 151 subjects with acute infarction within the middle cerebral artery (MCA) territory were included and patients with ipsilateral internal carotid artery stenosis or cardioembolism were excluded...
June 20, 2018: BMC Neurology
https://www.readbyqxmd.com/read/29924787/-staged-treatment-of-a-multilevel-lesion-of-brachiocephalic-arteries-in-combination-with-coronary-and-valvular-pathology-of-the-heart
#14
M A Cherniavskiĭ, A A Gusev, D V Chernova, I V Iarkov, M L Gordeev
Prevention of neurological complications in cardiosurgical and reconstructive vascular surgery is one of the priority tasks of preserving ability to work and decreasing invalidization of patients in the postoperative period. Presented in the article is a clinical case report regarding multiple-stage treatment of a female patient with a combined aortic defect, coronary pathology, and a multilevel bilateral lesion of the brachiocephalic arteries. The first stage consisted in performing a hybrid operation, i. e...
2018: Angiologii︠a︡ i Sosudistai︠a︡ Khirurgii︠a︡, Angiology and Vascular Surgery
https://www.readbyqxmd.com/read/29924783/-remote-results-of-eversion-carotid-endarterectomy-depending-on-the-suture-material-used
#15
D F Beloiartsev, O L Talybly
BACKGROUND: It is known that namely long-term presence of suture material as the only foreign body in autologous conditions may lead to restenosis in the remote period. Such hypothesis was put forward based on good results of reconstructive cardiovascular operations in case of using absorbable suture material. OBJECTIVE: Our study was aimed at comparative analysis of remote results of using absorbable suture material polydioxanone and non-absorbable suture material polypropylene in eversion carotid endarterectomy...
2018: Angiologii︠a︡ i Sosudistai︠a︡ Khirurgii︠a︡, Angiology and Vascular Surgery
https://www.readbyqxmd.com/read/29924781/-therapeutic-policy-in-stenosis-of-the-internal-carotid-artery-combined-with-intracranial-vascular-malformation
#16
A I Khripun, A D Priamikov, A B Mironkov, L D Gulina
Presented herein is the world experience of surgical treatment and various tactical approaches in a combined lesion of the extracranial and intracranial portions of the internal carotid artery (ICA): a combination of its stenosis or occlusion with vascular malformation of the brain (a cerebral aneurysm, pathological anastomoses, arteriovenous malformations). Also pointed out is the prevalence of the pathology involved, followed by describing various types of surgical policy in this condition: staged and simultaneous interventions, endovascular and standard operative auxiliary techniques...
2018: Angiologii︠a︡ i Sosudistai︠a︡ Khirurgii︠a︡, Angiology and Vascular Surgery
https://www.readbyqxmd.com/read/29923152/correlations-between-gene-expression-highlight-a-different-activation-of-ace-tlr4-ptgs2-signaling-in-symptomatic-and-asymptomatic-plaques-in-atherosclerotic-patients
#17
Silvia Ferronato, Alberto Scuro, Macarena Gomez-Lira, Sara Mazzucco, Silvia Olivato, Alberto Turco, Orlandi Elisa, Giovanni Malerba, Maria Grazia Romanelli
Inflammation has a key role and translates the effects of many known risk factors for the disease in atherosclerotic vulnerable plaques. Aiming to look into the elements that induce the development of either a vulnerable or stable atherosclerotic plaque, and considering that inflammation has a central role in the progression of lesions, we analyzed the expression of genes involved in the ACE/TLR4/PTGS2 signaling in carotid plaques of symptomatic and asymptomatic patients. Patients with internal carotid artery stenosis undergoing carotid endarterectomy at Verona University Hospital were included in this study...
June 19, 2018: Molecular Biology Reports
https://www.readbyqxmd.com/read/29922933/multidetector-ct-angiography-of-the-circle-of-willis-association-of-its-variants-with-carotid-artery-disease-and-brain-ischemia
#18
Andrea Varga, Giovanni Di Leo, Péter Vince Banga, Csaba Csobay-Novák, Márton Kolossváry, Pál Maurovich-Horvat, Kálmán Hüttl
PURPOSE: (1) to estimate the prevalence of Circle of Willis (CoW) variants in patients undergoing carotid endarterectomy, (2) to correlate these variants to controls and (3) cerebral ischemia depicted by computed tomography (CT). MATERIALS AND METHODS: After Institutional Review Board approval, data of 544 carotid endarterectomy patients (331 males, mean age 69±8 years) and 196 controls (117 males, mean age 66±11 years) who underwent brain CT and carotid CT angiography (CTA) were retrospectively analysed...
June 19, 2018: European Radiology
https://www.readbyqxmd.com/read/29922410/iatrogenic-extravasation-and-extracranial-ica-dissection-during-neurointervention-evaluated-by-transoral-carotid-ultrasonography-case-report
#19
Ryo Itabashi, Eisuke Furui, Ichiro Suzuki, Toshio Kikuchi, Ryushi Kondo, Yasushi Matsumoto, Satoru Fujiwara
We described an 88-year-old woman presented with large aneurysm on the carotid siphon of the right internal carotid artery (ICA). Digital subtraction angiography showed extravasation from the distal cervical segment of the right ICA due to positioning a guiding catheter for intra-aneurysmal coil embolization. Transoral carotid ultrasonography (TOCU) showed arrested bleeding and a pseudolumen in the distal cervical segment of the right ICA. We originally described that TOCU was useful for evaluating iatrogenic extravasation and extracranial ICA dissection during neurointervention...
June 2018: Journal of Vascular and Interventional Neurology
https://www.readbyqxmd.com/read/29922404/use-of-4d-computer-tomographic-angiography-to-accurately-identify-distal-internal-carotid-artery-occlusions-and-pseudo-occlusions-technical-note
#20
Stephan A Munich, Marshall C Cress, Leonardo Rangel-Castilla, Ashish Sonig, Chandan Krishna, Elad I Levy, Kenneth V Snyder, Adnan H Siddiqui
Background and Purpose: Traditional methods of computed tomographic angiography (CTA) can be unreliable in detecting carotid artery pseudo-occlusions or in accurately locating the site of carotid artery occlusion. With these methods, lack of adequate distal runoff due to pseudo-occlusion or intracranial occlusion can result in the inaccurate diagnoses of complete occlusion or cervical carotid occlusion, respectively. The site of carotid occlusion has important therapeutic and interventional considerations...
June 2018: Journal of Vascular and Interventional Neurology
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