keyword
https://read.qxmd.com/read/38733285/mohs-micrographic-surgery-in-immunosuppressed-vs-immunocompetent-patients-results-of-a-prospective-nationwide-cohort-study-regesmohs-spanish-registry-of-mohs-surgery
#1
JOURNAL ARTICLE
Carlos Abril-Pérez, Miguel Mansilla-Polo, Begoña Escutia-Muñoz, Onofre Sanmartín, Joan R Garcés, Manuel A Rodríguez-Prieto, Verónica Ruiz-Salas, Esther de Eusebio-Murillo, Román Miñano-Medrano, Beatriz González-Sixto, Juan L Artola-Igarza, Alberto Alfaro-Rubio, Pedro Redondo, Yolanda Delgado-Jiménez, Julia M Sánchez-Schmidt, Irati Allende-Markixana, María L Alonso-Pacheco, Beatriz García-Bracamonte, Pablo de la Cueva-Dobao, Raquel Navarro-Tejedor, Cristina Ciudad-Blanco, Lucía Carnero-González, Hugo Vázquez-Veiga, Natividad Cano-Martínez, Carlos Serra-Guillén, Eva Vilarrasa, Pedro Sánchez-Sambucety, José L López-Estebaranz, Ángeles Flórez-Menéndez, Antonio Martorell-Calatayud, Pilar Gil, Victoriano Morales-Gordillo, Agustí Toll, Izascun Ocerin-Guerra, Matías Mayor-Arenal, Ricardo Suárez-Fernández, Laura Sainz-Gaspar, Miguel A Descalzo, Ignacio Garcia-Doval, Rafael Botella-Estrada
BACKGROUND: Immunosuppressed (IS) patients, particularly solid organ transplant recipients and those on immunosuppressive therapy, face a higher incidence and recurrence of nonmelanoma skin cancers (NMSC), including basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). Mohs micrographic surgery (MMS) is the preferred treatment for high-risk NMSC due to its high cure rate and margin examination capabilities. However, IS patients may experience more complications, such as surgical site infections, and a greater risk of recurrence, making their outcomes a subject of interest...
May 11, 2024: Journal of the European Academy of Dermatology and Venereology: JEADV
https://read.qxmd.com/read/38732917/classification-of-sleep-quality-and-aging-as-a-function-of-brain-complexity-a-multiband-non-linear-eeg-analysis
#2
JOURNAL ARTICLE
Lucía Penalba-Sánchez, Gabriel Silva, Mark Crook-Rumsey, Alexander Sumich, Pedro Miguel Rodrigues, Patrícia Oliveira-Silva, Ignacio Cifre
Understanding and classifying brain states as a function of sleep quality and age has important implications for developing lifestyle-based interventions involving sleep hygiene. Current studies use an algorithm that captures non-linear features of brain complexity to differentiate awake electroencephalography (EEG) states, as a function of age and sleep quality. Fifty-eight participants were assessed using the Pittsburgh Sleep Quality Inventory (PSQI) and awake resting state EEG. Groups were formed based on age and sleep quality (younger adults n = 24, mean age = 24...
April 28, 2024: Sensors
https://read.qxmd.com/read/38732869/deep-learning-models-to-reduce-stray-light-in-tj-ii-thomson-scattering-diagnostic
#3
JOURNAL ARTICLE
Ricardo Correa, Gonzalo Farias, Ernesto Fabregas, Sebastián Dormido-Canto, Ignacio Pastor, Jesus Vega
Nuclear fusion is a potential source of energy that could supply the growing needs of the world population for millions of years. Several experimental thermonuclear fusion devices try to understand and control the nuclear fusion process. A very interesting diagnostic called Thomson scattering (TS) is performed in the Spanish fusion device TJ-II. This diagnostic takes images to measure the temperature and density profiles of the plasma, which is heated to very high temperatures to produce fusion plasma. Each image captures spectra of laser light scattered by the plasma under different conditions...
April 26, 2024: Sensors
https://read.qxmd.com/read/38732557/triglyceride-to-hdl-cholesterol-ratio-for-the-identification-of-masld-in-obesity-a-liver-biopsy-based-case-control-study
#4
JOURNAL ARTICLE
José Ignacio Martínez-Montoro, María Antonia Martínez-Sánchez, Andrés Balaguer-Román, Virginia Esperanza Fernández-Ruiz, José Emilio Hernández-Barceló, Mercedes Ferrer-Gómez, María Dolores Frutos, María Ángeles Núñez-Sánchez, José Carlos Fernández-García, Bruno Ramos-Molina
Associations between dyslipidemia and metabolic dysfunction-associated steatotic liver disease (MASLD) have been reported. Previous studies have shown that the triglyceride to high-density lipoprotein cholesterol (TG/HDL-C) ratio may be a surrogate marker of MASLD, assessed by liver ultrasound. However, no studies have evaluated the utility of this ratio according to biopsy-proven MASLD and its stages. Therefore, our aim was to evaluate if the TG/HDL-C ratio allows for the identification of biopsy-proven MASLD in patients with obesity...
April 27, 2024: Nutrients
https://read.qxmd.com/read/38731914/distinct-driver-pathway-enrichments-and-a-high-prevalence-of-tsc2-mutations-in-right-colon-cancer-in-chile-a-preliminary-comparative-analysis
#5
COMPARATIVE STUDY
Camilo Tapia-Valladares, Guillermo Valenzuela, Evelin González, Ignacio Maureira, Jessica Toro, Matías Freire, Gonzalo Sepúlveda-Hermosilla, Diego Ampuero, Alejandro Blanco, Iván Gallegos, Fernanda Morales, José I Erices, Olga Barajas, Mónica Ahumada, Héctor R Contreras, Jaime González, Ricardo Armisén, Katherine Marcelain
Colorectal cancer (CRC) is the second leading cause of cancer deaths globally. While ethnic differences in driver gene mutations have been documented, the South American population remains understudied at the genomic level, despite facing a rising burden of CRC. We analyzed tumors of 40 Chilean CRC patients (Chp) using next-generation sequencing and compared them to data from mainly Caucasian cohorts (TCGA and MSK-IMPACT). We identified 388 mutations in 96 out of 135 genes, with TP53 (45%), KRAS (30%), PIK3CA (22...
April 25, 2024: International Journal of Molecular Sciences
https://read.qxmd.com/read/38731321/osteolytic-lesions-in-a-sub-adult-loggerhead-sea-turtle-caretta-caretta-a-case-report
#6
JOURNAL ARTICLE
Ignacio Peña Pascucci, Susana Pernas Mozas, Lucía Garrido Sánchez
Osteolytic lesions in loggerhead sea turtles ( Caretta caretta ) during rehabilitation are attributed to multiple causes, including gas embolism, hypothermia, and osteomyelitis due to bacterial or fungal infection. This study reports the appearance of osteolytic lesions in a sub-adult loggerhead sea turtle with involvement of the right fore and hind flippers, visible swelling of the elbow and knee joints, and accompanied by lameness after 45 days of rehabilitation. Radiographs and computed tomography revealed multiple lytic bone lesions...
April 27, 2024: Animals: An Open Access Journal From MDPI
https://read.qxmd.com/read/38731043/a-prospective-observational-study-of-frailty-in-geriatric-revitalization-aimed-at-community-dwelling-elderly
#7
JOURNAL ARTICLE
Almudena Morales-Sánchez, José Ignacio Calvo Arenillas, María José Gutiérrez Palmero, José L Martín-Conty, Begoña Polonio-López, Luís Alonso Dzul López, Laura Mordillo-Mateos, Juan José Bernal-Jiménez, Rosa Conty-Serrano, Francisca Torres-Falguera, Alfonso Martínez Cano, Carlos Durantez-Fernández
(1) Background: The increasing life expectancy brings an increase in geriatric syndromes, specifically frailty. The literature shows that exercise is a key to preventing, or even reversing, frailty in community-dwelling populations. The main objective is to demonstrate how an intervention based on multicomponent exercise produces an improvement in frailty and pre-frailty in a community-dwelling population. (2) Methods: a prospective observational study of a multicomponent exercise program for geriatric revitalization with people aged over 65 holding Barthel Index scores equal to, or beyond, 90...
April 25, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38730936/effect-of-luting-materials-on-the-accuracy-of-fit-of-zirconia-copings-a-non-destructive-digital-analysis-method
#8
JOURNAL ARTICLE
Lara Berger, Ragai-Edward Matta, Christian Markus Weiß, Werner Adler, Manfred Wichmann, José Ignacio Zorzin
The marginal accuracy of fit between prosthetic restorations and abutment teeth represents an essential aspect with regard to long-term clinical success. Since the final gap is also influenced by the luting techniques and materials applied, this study analyzed the accuracy of the fit of single-tooth zirconia copings before and after cementation using different luting materials. Forty plaster dies with a corresponding zirconia coping were manufactured based on a single tooth chamfer preparation. The copings were luted on the plaster dies ( n = 10 per luting material) with a zinc phosphate (A), glass-ionomer (B), self-adhesive resin (C), or resin-modified glass-ionomer cement (D)...
May 1, 2024: Materials
https://read.qxmd.com/read/38730696/evolution-of-complexity-of-palliative-care-needs-and-patient-profiles-according-to-the-palcom-scale-part-two-pooled-analysis-of-the-cohorts-for-the-development-and-validation-of-the-palcom-scale-in-advanced-cancer-patients
#9
JOURNAL ARTICLE
Albert Tuca, Margarita Viladot, Gemma Carrera, Lucia Llavata, Carmen Barrera, Manoli Chicote, Javier Marco-Hernández, Joan Padrosa, Carles Zamora-Martínez, Ignacio Grafia, Anais Pascual, Carme Font, Elena Font
INTRODUCTION: Identifying the complexity of palliative care needs is a key aspect of referral to specialized multidisciplinary early palliative care (EPC) teams. The PALCOM scale is an instrument consisting of five multidimensional assessment domains developed in 2018 and validated in 2023 to identify the level of complexity in patients with advanced cancer. (1) Objectives: The main objective of this study was to determine the degree of instability (likelihood of level change or death), health resource consumption and the survival of patients according to the level of palliative complexity assigned at the baseline visit during a 6-month follow-up...
April 29, 2024: Cancers
https://read.qxmd.com/read/38729757/tobacco-policies-and-changes-in-the-tendency-of-smoking-cessation-in-cigarette-users-in-chile-a-longitudinal-cross-sectional-study
#10
JOURNAL ARTICLE
Karen A Dominguez-Cancino, Pablo Martínez, José Ignacio Nazif-Muñoz
OBJECTIVE: To assess the impact of tobacco control regulations and policy implementation on smoking cessation tendencies in cigarette users born between 1982 and 1991 in Chile. DESIGN: Longitudinal cross-sectional study. SETTING: National level. PARTICIPANTS: Data from the National Survey of Drug Consumption (Service of Prevention and Rehabilitation for Drug and Alcohol Consumption). A pseudo-cohort of smokers born between 1982 and 1991 (N=17 905) was tracked from 2002 to 2016...
May 10, 2024: BMJ Open
https://read.qxmd.com/read/38729732/benefit-of-the-nutritional-and-mineral-composition-of-sea-lettuce-from-a-traditional-salina-implications-for-human-consumption
#11
JOURNAL ARTICLE
Fini Sánchez-García, Víctor M Palacios, Ignacio Hernández, Ana M Roldán
The proximal composition and its seasonal variation of the green seaweed Ulva sp. harvested in a traditional saline (earthen ponds used for marine salt extraction) from Cadiz Bay (Southern Spain) was evaluated. Ulva sp. was also collected in a reference location within the Bay in order to compare and evaluate the effects of the particular characteristics of the saline in the composition of the macroalgae. Moisture, protein, lipid, ash, carbohydrate, fiber and macro- (Na, K, Ca, Mg), micro-mineral contents (Fe, Zn, Cu) and heavy metals (As, Cd, Co, Cr, Hg, Ni, Pb, Sn) of harvested biomass samples as well as environmental parameters of seawater (temperature, salinity, pH, DO, NH4 + , NO3 - , NO2 - and PO4 3- ) were measured...
June 2024: Food Research International
https://read.qxmd.com/read/38729082/relationship-between-natural-muscle-oscillation-frequency-and-lower-limb-muscle-performance-during-instrumented-sit-to-stand-and-stand-to-sit-movements-on-a-novel-device-in-sedentary-subjects
#12
JOURNAL ARTICLE
Maximiliano Torres-Banduc, Daniel Jerez-Mayorga, Luis Chirosa-Ríos, Paula Plaza, Ignacio Chirosa-Ríos
BACKGROUND: Despite the significance of muscle oscillation frequency, previous research has not established a correlation with muscle performance due to the challenges of applying resistance without altering natural motion during functional tests. RESEARCH QUESTION: What is the correlation between muscle oscillation frequency and lower limb muscle strength, power, and work during an instrumented sit-to-stand and stand-to- sit (iSTS-TS) task among sedentary subjects? METHODS: In a cross-sectional study, the oscillation frequency of the gastrocnemius medialis (GM), biceps femoralis (BF), and vastus medialis (VM) muscles in both the dominant (D) and non-dominant (ND) legs was assessed with a handheld myotonometer in 34 sedentary individuals before performing the iSTS-TS task...
May 8, 2024: Gait & Posture
https://read.qxmd.com/read/38728580/discovery-of-potent-glycosidases-enables-quantification-of-smoke-derived-phenolic-glycosides-through-enzymatic-hydrolysis
#13
JOURNAL ARTICLE
Youtian Cui, Mary Riley, Marcus V Moreno, Mateo M Cepeda, Ignacio Arias Perez, Yan Wen, Lik Xian Lim, Eric Andre, An Nguyen, Cody Liu, Larry Lerno, Patrick K Nichols, Harold Schmitz, Ilias Tagkopoulos, James A Kennedy, Anita Oberholster, Justin B Siegel
When grapes are exposed to wildfire smoke, certain smoke-related volatile phenols (VPs) can be absorbed into the fruit, where they can be then converted into volatile-phenol (VP) glycosides through glycosylation. These volatile-phenol glycosides can be particularly problematic from a winemaking standpoint as they can be hydrolyzed, releasing volatile phenols, which can contribute to smoke-related off-flavors. Current methods for quantitating these volatile-phenol glycosides present several challenges, including the requirement of expensive capital equipment, limited accuracy due to the molecular complexity of the glycosides, and the utilization of harsh reagents...
May 10, 2024: Journal of Agricultural and Food Chemistry
https://read.qxmd.com/read/38728072/spanish-and-catalan-versions-of-the-ehealth-literacy-questionnaire-translation-cross-cultural-adaptation-and-validation-study
#14
JOURNAL ARTICLE
Eulàlia Hernández Encuentra, Noemí Robles, Ariadna Angulo-Brunet, David Cullen, Ignacio Del Arco
BACKGROUND: The rise of digital health services, especially following the outbreak of COVID-19, has led to a need for health literacy policies that respond to people's needs. Spain is a country with a highly developed digital health infrastructure, but there are currently no tools available to measure digital health literacy fully. A well-thought-through questionnaire with strong psychometric properties such as the eHealth Literacy Questionnaire (eHLQ) is important to assess people's eHealth literacy levels, especially in the context of a fast-growing field such as digital health...
May 10, 2024: Journal of Medical Internet Research
https://read.qxmd.com/read/38728033/long-term-effect-of-home-blood-pressure-self-monitoring-plus-medication-self-titration-for-patients-with-hypertension-a-secondary-analysis-of-the-adampa-randomized-clinical-trial
#15
RANDOMIZED CONTROLLED TRIAL
Patricia Martínez-Ibáñez, Irene Marco-Moreno, Aníbal García-Sempere, Salvador Peiró, Lucia Martínez-Ibáñez, Ignacio Barreira-Franch, Laura Bellot-Pujalte, Eugenia Avelino-Hidalgo, Marina Escrig-Veses, María Bóveda-García, Mercedes Calleja-Del-Ser, Celia Robles-Cabaniñas, Isabel Hurtado, Clara L Rodríguez-Bernal, Margarita Giménez-Loreiro, Gabriel Sanfélix-Gimeno, José Sanfélix-Genovés
IMPORTANCE: Patient empowerment through pharmacologic self-management is a common strategy for some chronic diseases such as diabetes, but it is rarely used for controlling blood pressure (BP). Several trials have shown its potential for reducing BP in the short term, but evidence in the longer term is scarce. OBJECTIVE: To evaluate the longer-term effectiveness of BP self-monitoring plus self-titration of antihypertensive medication vs usual care for patients with poorly controlled hypertension, with passive follow-up and primary-care nursing involvement...
May 1, 2024: JAMA Network Open
https://read.qxmd.com/read/38726856/transferring-emergence-profile-and-position-of-interim-restorative-implant-fixture-a-novel-digital-technique
#16
JOURNAL ARTICLE
Juan Mesquida, Diogo Firmino, Carmen Matji, Ignacio Ginebreda, Israel Puterman, Matthew J Fien, Alvaro Blasi, Renaud Noharet, Guillermo Bauza
The present technical article describes a protocol to digitally reproduce the emergence profile of an interim implant prosthesis (IP) and to transfer its macrogeometry into the definitive restoration. The purpose of this protocol was to minimize alterations in the gingival architecture developed during the interim restorative phase of a single implant that could potentially jeopardize its esthetic outcome. The process included obtaining an intraoral scan with the interim IP in situ, a duplicate of this intraoral scan that was used to capture the exact position of the implant, and an extraoral scan of the prosthesis...
May 10, 2024: International Journal of Esthetic Dentistry
https://read.qxmd.com/read/38726853/ijed-espresso
#17
EDITORIAL
Ignacio Farga-Niñoles, Irene Manuel-Garcia
No abstract text is available yet for this article.
May 10, 2024: International Journal of Esthetic Dentistry
https://read.qxmd.com/read/38726586/-infographing-dementia-prevention-a-co-design-approach
#18
JOURNAL ARTICLE
Ignacio Martinez Escobedo, Kathleen Doherty, Claire Eccleston
Designing effective public health messages is challenging, particularly when communicating complex and relatively new health messages such as dementia risk prevention which are still largely unfamiliar to the public. The accessibility of these messages, especially for individuals who speak English as an additional language, remains uncertain in large scale educational interventions. A key strategy to enhance the communication of evidence-based information is to co-design infographics that optimize the accessibility and impact of visual health messages...
May 10, 2024: Health Communication
https://read.qxmd.com/read/38725634/pain-management-in-cervical-cancer
#19
REVIEW
Sebastián Aguiar-Rosas, Ricardo Plancarte-Sanchez, B Carolina Hernandez-Porras, Jorge García-Andreu, Brenda Olivia Lezcano-Velazquez, Ignacio Reyes-Torres, Silvia Alarcón-Barrios
Cervical cancer (CC) occupies the second place in incidence and mortality among women in México. Despite this, Cervical Cancer continues to have a late diagnosis which leads to a high rate of complications. Pain represents the most feared and disabling symptom, being present in up to 86% of patients with advanced disease. The approach to managing pain in this population has not been studied and described to a full extent. In addition, there is a pressing need to provide concise recommendations to promote adequate pain control...
2024: Frontiers in Oncology
https://read.qxmd.com/read/38725465/inhibin-b-and-antim%C3%A3-llerian-hormone-as-surrogate-markers-of-fertility-in-male-and-female-crohn-s-disease-patients-a-case-control-study
#20
JOURNAL ARTICLE
Ana Gutiérrez, Roser Muñoz-Pérez, Pedro Zapater, Cristina Mira, Andrés Rodríguez, Laura Sempere-Robles, María Eugenia Torregrosa, Rocio Alfayate, Violeta Moreno-Torres, Lorena Bernal, Olivia Belén-Galipienso, Jose Ignacio Cameo, Paula Sirera, Belen Herreros, Puri Bernabeu, Oscar Moreno-Pérez, Lucía Madero-Velázquez
BACKGROUND: Several studies suggest that women with Crohn disease (CD) have reduced fertility due to decreased ovarian reserve, among other causes. On the other hand, male CD patients could have difficulties conceiving. The present study aimed to test the effect of CD on both male and female fertility potential, Sertoli cell function and ovarian reserve, assessed by inhibin-B (IB) plus IB:FSH ratio (IFR) and antiMüllerian hormone (AMH), respectively. Sexual dysfunction (SD) was studied as secondary endpoint...
2024: Frontiers in Medicine
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