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https://www.readbyqxmd.com/read/28103519/do-cognitive-schema-mediate-the-association-between-childhood-trauma-and-being-at-ultra-high-risk-for-psychosis
#1
E Appiah-Kusi, H L Fisher, N Petros, R Wilson, V Mondelli, P A Garety, P Mcguire, S Bhattacharyya
Exposure to childhood trauma has been associated with psychotic symptoms, being at ultra-high risk for psychosis (UHR), and psychotic disorders such as schizophrenia. Negative self-beliefs have been shown to partially mediate the relationship between childhood trauma and paranoia and have been shown to be characteristic of patients with psychosis. However, whether the association between childhood trauma and being at high risk of developing psychosis (e.g., UHR) and paranoia symptoms is mediated by altered cognitive schema is unknown and warrants investigation to inform preventive interventions...
January 6, 2017: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/28095254/maternal-psychological-distress-during-pregnancy-does-not-increase-the-risk-for-adverse-birth-outcomes
#2
Aleksandra Staneva, Alina Morawska, Fiona Bogossian, Anja Wittkowski
Maternal psychological distress during pregnancy is a potential risk factor for various birth complications. This study aimed to explore psychological factors associated with adverse birth outcomes. Symptoms of psychological distress, individual characteristics, and medical complications were assessed at two time points antenatally in 285 women from Australia and New Zealand; birth outcomes were assessed postpartum, between January 2014 and September 2015. Hierarchical multiple regression analyses were conducted to examine the relation of psychological distress to adverse birth outcomes...
January 17, 2017: Women & Health
https://www.readbyqxmd.com/read/28088618/modelling-possible-causality-in-the-associations-between-unemployment-cannabis-use-and-alcohol-misuse
#3
Joseph M Boden, Jungeun Olivia Lee, L John Horwood, Carolina Villamil Grest, Geraldine F H McLeod
BACKGROUND: There has been considerable interest in the extent to which substance use and unemployment may be related, particularly the causal pathways that may be involved in these associations. It has been argued that these associations may reflect social causation, in which unemployment influences substance use, or that they may reflect social selection, in which substance use increases the risk of becoming and remaining unemployed. The present study sought to test these competing explanations...
January 3, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28081435/heavy-episodic-drinking-and-alcohol-related-injuries-an-open-cohort-study-among-college-students
#4
Francisco Caamaño-Isorna, Lucía Moure-Rodríguez, Sonia Doallo, Montserrat Corral, Socorro Rodriguez Holguín, Fernando Cadaveira
AIM: The objective of this study is to assess the effects of Heavy Episodic Drinking (HED) on the incidence of alcohol-related injuries among university students in Spain, taking sex into consideration. METHODS: We carried out an open cohort study among college students in Spain (992 women and 371 men). HED and alcohol-related injuries were measured by question 3rd and 9th of Alcohol Use Disorders Identification Test to every participant at the ages of 18, 20, 22, 24 and 27...
January 9, 2017: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/28078706/commentary-on-kosty-et-al-2017-understanding-risk-classes-for-cannabis-use-disorder-requires-knowledge-of-exposure-environment-and-genetic-effects
#5
https://www.readbyqxmd.com/read/28076983/multidimensional-family-therapy-reduces-self-reported-criminality-among-adolescents-with-a-cannabis-use-disorder
#6
Thimo M van der Pol, Craig E Henderson, Vincent Hendriks, Michael P Schaub, Henk Rigter
Multidimensional family therapy (MDFT) is an established treatment program for youth displaying multiproblem behavior. We examined whether MDFT decreased criminal offending among cannabis abusing adolescents, as compared with individual psychotherapy (IP). In a Western European randomized controlled trial comparing MDFT with IP, a sample of 169 adolescents with a cannabis disorder completed self-reports on criminal offending. Half indicated they had committed one or more criminal offenses in the 90 days before the baseline assessment...
January 1, 2017: International Journal of Offender Therapy and Comparative Criminology
https://www.readbyqxmd.com/read/28073157/comparison-of-parent-peer-psychiatric-and-cannabis-use-influences-across-stages-of-offspring-alcohol-involvement-evidence-from-the-coga-prospective-study
#7
Kathleen K Bucholz, Vivia V McCutcheon, Arpana Agrawal, Danielle M Dick, Victor M Hesselbrock, John R Kramer, Samuel Kuperman, John I Nurnberger, Jessica E Salvatore, Marc A Schuckit, Laura J Bierut, Tatiana M Foroud, Grace Chan, Michie Hesselbrock, Jacquelyn L Meyers, Howard J Edenberg, Bernice Porjesz
BACKGROUND: All stages of development of alcohol use disorder (AUD) have not been equally studied. While initiation of drinking has been given considerable attention, other stages have not been as thoroughly investigated. It is not clear whether the same factors are associated consistently across early and late transitions in AUD involvement. High-risk family samples that are enriched for AUD vulnerability and transitions in AUD development offer an opportunity to examine influences across multiple stages of AUD development...
January 10, 2017: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/28065168/functional-outcomes-of-child-and-adolescent-mental-disorders-current-disorder-most-important-but-psychiatric-history-matters-as-well
#8
J Ormel, A M Oerlemans, D Raven, O M Laceulle, C A Hartman, R Veenstra, F C Verhulst, W Vollebergh, J G M Rosmalen, S A Reijneveld, A J Oldehinkel
BACKGROUND: Various sources indicate that mental disorders are the leading contributor to the burden of disease among youth. An important determinant of functioning is current mental health status. This study investigated whether psychiatric history has additional predictive power when predicting individual differences in functional outcomes. METHOD: We used data from the Dutch TRAILS study in which 1778 youths were followed from pre-adolescence into young adulthood (retention 80%)...
January 9, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28051838/mixed-amphetamine-salts-increase-abstinence-from-marijuana-in-patients-with-co-occurring-attention-deficit-hyperactivity-disorder-and-cocaine-dependence
#9
Daniel P Notzon, John J Mariani, Martina Pavlicova, Andrew Glass, Amy L Mahony, Daniel J Brooks, John Grabowski, Frances R Levin
BACKGROUND AND OBJECTIVES: The prevalence of ADHD is greater in substance use disorders than the general population, and ADHD and substance use disorders share neurobiological features such as dysregulation of reward circuitry. We tested the hypothesis that stimulants would decrease marijuana use in a randomized controlled trial of extended release mixed amphetamine salts (MAS-XR) for treatment of co-occurring ADHD and cocaine use disorders. METHODS: Marijuana users were defined as participants reporting use in the 30 days before study initiation, collected with timeline follow-back...
December 2016: American Journal on Addictions
https://www.readbyqxmd.com/read/28049102/prevalence-and-clinical-severity-of-mood-disorders-among-first-second-and-third-generation-migrants
#10
Baptiste Pignon, Geoffroy Pierre Alexis, Pierre Thomas, Jean-Luc Roelandt, Benjamin Rolland, Craig Morgan, Guillaume Vaiva, Ali Amad
BACKGROUND: The role of migration as a risk factor remains unknown for mood disorders because of poor data. We sought to examine the prevalence and severity of mood disorders (bipolar disorder (BD), unipolar depressive disorder (UDD) and dysthymia) in first, second, and third generation migrants in France. METHODS: The Mental Health in the General Population survey interviewed 38,694 individuals. The prevalence of lifetime mood disorders, comorbidities, and clinical features was compared between migrants and non-migrants and by generation...
December 27, 2016: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28029515/the-polyenviromic-risk-score-aggregating-environmental-risk-factors-predicts-conversion-to-psychosis-in-familial-high-risk-subjects
#11
Jaya L Padmanabhan, Jai L Shah, Neeraj Tandon, Matcheri S Keshavan
BACKGROUND: Young relatives of individuals with schizophrenia (i.e. youth at familial high-risk, FHR) are at increased risk of developing psychotic disorders, and show higher rates of psychiatric symptoms, cognitive and neurobiological abnormalities than non-relatives. It is not known whether overall exposure to environmental risk factors increases risk of conversion to psychosis in FHR subjects. METHODS: Subjects consisted of a pilot longitudinal sample of 83 young FHR subjects...
October 29, 2016: Schizophrenia Research
https://www.readbyqxmd.com/read/28006972/identifying-hiv-care-enrollees-at-risk-for-cannabis-use-disorder
#12
Bryan Hartzler, Beatriz H Carlini, Howard Newville, Heidi M Crane, Joseph J Eron, Elvin H Geng, W Christopher Mathews, Kenneth H Mayer, Richard D Moore, Michael J Mugavero, Sonia Napravnik, Benigno Rodriguez, Dennis M Donovan
Increased scientific attention given to cannabis in the United States has particular relevance for its domestic HIV care population, given that evidence exists for both cannabis as a therapeutic agent and cannabis use disorder (CUD) as a barrier to antiretroviral medication adherence. It is critical to identify relative risk for CUD among demographic subgroups of HIV patients, as this will inform detection and intervention efforts. A Center For AIDS Research Network of Integrated Clinical Systems cohort (N = 10,652) of HIV-positive adults linked to care at seven United State sites was examined for this purpose...
December 23, 2016: AIDS Care
https://www.readbyqxmd.com/read/28000973/quality-of-life-and-recreational-cannabis-use
#13
REVIEW
Matthew Goldenberg, Waguih William IsHak, Itai Danovitch
INTRODUCTION: Cannabis is now the most commonly used illicit drug in the United States and use is increasing. Frequent cannabis use has been associated with adverse social and health effects. We sought to evaluate the relationship between recreational cannabis use and Quality of Life (QoL), a person-centered measure that characterizes the overall sense of health and wellbeing. We hypothesized that QoL would be unchanged or increased among recreational cannabis users, who did not meet criteria for a Cannabis Use Disorder (CUD) and that QoL would be lower among those who met criteria for a CUD...
January 2017: American Journal on Addictions
https://www.readbyqxmd.com/read/27991999/attention-deficit-hyperactivity-disorder-and-drug-addiction-rehabilitation-patients
#14
Carlos Henrique Ferreira Camargo, Tarcísio Fanha Dornelles, Karin Barszcz, Eduardo Antunes Martins
Objective: Attention deficit hyperactivity disorder (ADHD) is characterized by a persistent pattern of inattention or hyperactivity. This study aimed to investigate the relationship between ADHD and drug dependence. Methods: The presence and severity of ADHD and substance use were evaluated through questionnaires in 80 adult patients in therapeutic communities. Results: No difference in drug use or dependence prevalence between ADHD and non-ADHD patients was found...
December 2016: Arquivos de Neuro-psiquiatria
https://www.readbyqxmd.com/read/27936363/predictors-of-patterns-of-alcohol-related-blackouts-over-time-in-youth-from-the-collaborative-study-of-the-genetics-of-alcoholism-the-roles-of-genetics-and-cannabis
#15
Marc A Schuckit, Tom L Smith, Alexandra Shafir, Peyton Clausen, George Danko, Priscila Dib Gonçalves, Robert M Anthenelli, Grace Chan, Samuel Kuperman, Michie Hesselbrock, Victor Hesselbrock, John Kramer, Kathleen K Bucholz
OBJECTIVE: Alcohol-related blackouts (ARBs) are anterograde amnesias related to heavy alcohol intake seen in about 50% of drinkers. Although a major determinant of ARBs relates to blood alcohol concentrations, additional contributions come from genetic vulnerabilities and possible impacts of cannabis use disorders (CUDs). We evaluated relationships of genetics and cannabis use to latent class trajectories of ARBs in 829 subjects from the Collaborative Study of the Genetics of Alcoholism (COGA)...
January 2017: Journal of Studies on Alcohol and Drugs
https://www.readbyqxmd.com/read/27903036/cannabis-use-and-its-associated-disorders-clinical-care
#16
Jan Copeland
BACKGROUND: Globally, cannabis is the most widely used and variably regulated illicit drug. The rates of use appeared to be stable in Australia at the time of the 2013 National Drug Strategy Household Survey, but levels of cannabis use disorder are rising and treatment seeking is increasing internationally. OBJECTIVE: This article describes the prevalence of cannabis use, associated disorders (eg harms with early and frequent use), and information on assessment and management...
December 2016: Australian Family Physician
https://www.readbyqxmd.com/read/27901585/a-review-of-positron-emission-tomography-studies-exploring-the-dopaminergic-system-in-substance-use-with-a-focus-on-tobacco-as-a-co-variate
#17
Thulasi Thiruchselvam, Saima Malik, Bernard Le Foll
With the evolving sensitivity of positron emission tomography (PET) and the emergence of novel radiotracers, greater insight has been gained into the dopaminergic system as it relates to substance use. In this review, we summarize PET investigations from the last ten years that explore the dopaminergic system in tobacco, alcohol, stimulant, opiates, and cannabis addiction. In light of the prevalence of substance co-use, this review will also explore the effect of tobacco and other substance abuse co-morbidity on the dopaminergic system across study samples in the reviewed literature...
November 30, 2016: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/27888680/symptomatic-and-functional-outcomes-of-substance-use-disorder-persistence-2-years-after-admission-to-a-first-episode-psychosis-program
#18
Amal Abdel-Baki, Clairélaine Ouellet-Plamondon, Émilie Salvat, Kawthar Grar, Stéphane Potvin
Substance use disorders (SUD) in first-episode psychosis (FEP) are highly prevalent and linked with poor outcomes. However, most longitudinal studies investigating their impacts in FEP have not reported proportions of patients who ceased SUD. Our aim was to examine the influence of SUD course on functional and symptomatic outcomes as well as service use in FEP. We performed a 2-year longitudinal study of 212 FEP patients, aged between 18 and 30 years, admitted to 2 early psychosis services in Montréal, Québec, Canada...
January 2017: Psychiatry Research
https://www.readbyqxmd.com/read/27886010/discriminative-properties-of-hippocampal-hypoperfusion-in-marijuana-users-compared-to-healthy-controls-implications%C3%A2-for-marijuana-administration%C3%A2-in%C3%A2-alzheimer-s-dementia
#19
Daniel G Amen, Borhan Darmal, Cyrus A Raji, Weining Bao, Lantie Jorandby, Somayeh Meysami, Cauligi S Raghavendra
BACKGROUND: Few studies have evaluated the impact of marijuana use on regional cerebral blood flow. OBJECTIVE: To determine whether perfusion in specific brain regions on functional neuroimaging, including those affected by Alzheimer's disease pathology, are abnormal in marijuana users compared to controls. METHOD: Persons with a diagnosis of cannabis use disorder by DSM-IV and DSM-V criteria (n = 982) were compared to controls (n = 92) with perfusion neuroimaging with SPECT at rest and at a concentration task...
November 24, 2016: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/27883947/social-cognitive-predictors-of-treatment-outcome-in-cannabis-dependence
#20
Matthew J Gullo, Marya Matveeva, Gerald F X Feeney, Ross McD Young, Jason P Connor
BACKGROUND: Drug-related outcomes expectancies and refusal self-efficacy are core components of Social Cognitive Theory. Both predict treatment outcome in alcohol use disorders. Few studies have reported expectancies and refusal self-efficacy in cannabis dependence. None have examined both, although both constructs are key targets in Cognitive-Behavioural Therapy (CBT). This study tests the predictive role of expectancies and refusal self-efficacy in treatment outcome for cannabis dependence...
January 1, 2017: Drug and Alcohol Dependence
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