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cannabis use disorder

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https://www.readbyqxmd.com/read/28648138/psychological-symptomatology-and-impaired-prepulse-inhibition-of-the-startle-reflex-are-associated-with-cannabis-induced-psychosis
#1
Isabel Morales-Muñoz, Isabel Martínez-Gras, Guillermo Ponce, Javier de la Cruz, David Lora, Roberto Rodríguez-Jiménez, Rosa Jurado-Barba, Francisco Navarrete, María Salud García-Gutiérrez, Jorge Manzanares, Gabriel Rubio
BACKGROUND: Cannabis-induced psychotic disorder (CIPD) is a psychiatric disorder induced by cannabis consumption. The psychological and psychophysiological features of this disorder are still unknown. We aimed to examine the psychological, personality and psychophysiological features of patients with CIPD. This study is an analytical extension of our previously published data, which previously found prepulse inhibition (PPI) deficits in the CIPD group used in this current paper. METHODS: We used a sample of 45 patients with CIPD...
June 1, 2017: Journal of Psychopharmacology
https://www.readbyqxmd.com/read/28646712/prediction-of-vocational-participation-and-global-role-functioning-in-help-seeking-young-adults-from-neurocognitive-demographic-and-clinical-variables
#2
Alice J Cairns, David J Kavanagh, Frances Dark, Steven M McPhail
BACKGROUND: The purpose of this study was to investigate neurocognitive, demographic and clinical correlates of vocational participation among a sample of young help-seeking adults. METHODS: Young people (18-25 years) accessing an early intervention youth health service participated. The Global Functioning: Role scale and level of vocational participation, participant characteristics (age, gender, socioeconomic background and family history of serious mental illness), distress, psychotic-like experiences, substance use, and mental health diagnoses were recorded...
June 13, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28639495/substance-use-in-adolescents-with-mental-illness-in-durban-south-africa
#3
Bhoodeo Taukoor, Saeeda Paruk, Enver Karim, Jonathan K Burns
Comorbid substance use in adolescents with mental illness is often an indicator of poor treatment outcome. This study aims to determine the prevalence of, and associated risk factors for, substance use in adolescents with mental illness attending a mental health service. Data was collected from hospital records of 162 adolescents, using a structured data sheet, over a two-year period. Substance use was more significant in older adolescents and those with severe mental illness. Sixty-two (38.3%) adolescents used substances...
May 2017: Journal of Child and Adolescent Mental Health
https://www.readbyqxmd.com/read/28639209/substance-use-and-misuse-among-children-and-youth-with-mental-illness-a%C3%A2-pilot-study
#4
V Herz, N Franzin, J Huemer, D Mairhofer, J Philipp, K Skala
OBJECTIVE: The aim of this study was to examine prevalence, patterns and predictors of substance use among a sample of adolescent psychiatric inpatients. METHODS: Participants included 25 minors aged 12-17 years admitted to an Austrian department of child and adolescent psychiatry. Lifetime use, initiation, frequency and quantity of substance use, sociodemographic, family and school-related data were collected by self-report measures. Substance use disorders were detected using CAGE (a screening instrument for problem drinking) and FTND (Fagerström Test For Nicotine Dependence)...
June 21, 2017: Neuropsychiatrie: Klinik, Diagnostik, Therapie und Rehabilitation
https://www.readbyqxmd.com/read/28636769/is-cannabis-treatment-for-anxiety-mood-and-related-disorders-ready-for-prime-time
#5
REVIEW
Jasmine Turna, Beth Patterson, Michael Van Ameringen
Anxiety and related disorders are the most common mental conditions affecting the North American population. Despite their established efficacy, first-line antidepressant treatments are associated with significant side effects, leading many afflicted individuals to seek alternative treatments. Cannabis is commonly viewed as a natural alternative for a variety of medical and mental health conditions. Currently, anxiety ranks among the top five medical symptoms for which North Americans report using medical marijuana...
June 21, 2017: Depression and Anxiety
https://www.readbyqxmd.com/read/28635349/the-association-between-alcohol-use-trajectories-from-adolescence-to-adulthood-and-cannabis-use-disorder-in-adulthood-a-22-year-longitudinal-study
#6
Jung Yeon Lee, Judith S Brook, Mario De La Rosa, Youngjin Kim, David W Brook
BACKGROUND: Due to the increasing prevalence of cannabis use disorder (CUD), the impact of cannabis use on public health may be significant. OBJECTIVE: The present study seeks the possible precursors (e.g., alcohol use) of CUD in order to minimize the potential negative consequences of CUD such as impaired coordination and performance. METHOD: The Harlem Longitudinal Development Study included 674 participants (53% African Americans, 47% Puerto Ricans), with 60% females (n=405) from a six wave survey...
March 1, 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/28627903/predictors-of-substance-use-in-youth-with-borderline-personality-disorder
#7
Franco Scalzo, Carol A Hulbert, Jennifer K Betts, Sue M Cotton, Andrew M Chanen
Concomitant substance misuse in adults with borderline personality disorder (BPD) is associated with a more severe course of illness and poorer outcomes. Previous research has found an association between the number of borderline personality features and substance misuse in community samples. This study examined the relationship between substance use and severity of BPD in youth presenting for the first time for treatment (first presentation) of BPD. Participants were 117 help-seeking youth aged 15-25 years (93 females; Mage = 19...
June 19, 2017: Personality Disorders
https://www.readbyqxmd.com/read/28623823/a-randomized-placebo-controlled-trial-of-n-acetylcysteine-for-cannabis-use-disorder-in-adults
#8
Kevin M Gray, Susan C Sonne, Erin A McClure, Udi E Ghitza, Abigail G Matthews, Aimee L McRae-Clark, Kathleen M Carroll, Jennifer S Potter, Katharina Wiest, Larissa J Mooney, Albert Hasson, Sharon L Walsh, Michelle R Lofwall, Shanna Babalonis, Robert W Lindblad, Steven Sparenborg, Aimee Wahle, Jacqueline S King, Nathaniel L Baker, Rachel L Tomko, Louise F Haynes, Ryan G Vandrey, Frances R Levin
BACKGROUND: Cannabis use disorder (CUD) is a prevalent and impairing condition, and established psychosocial treatments convey limited efficacy. In light of recent findings supporting the efficacy of N-acetylcysteine (NAC) for CUD in adolescents, the objective of this trial was to evaluate its efficacy in adults. METHODS: In a 12-week double-blind randomized placebo-controlled trial, treatment-seeking adults ages 18-50 with CUD (N=302), enrolled across six National Drug Abuse Treatment Clinical Trials Network-affiliated clinical sites, were randomized in a 1:1 ratio to a 12-week course of NAC 1200mg (n=153) or placebo (n=149) twice daily...
June 10, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28622571/substantiated-childhood-maltreatment-and-young-adulthood-cannabis-use-disorders-a-pre-birth-cohort-study
#9
Amanuel Alemu Abajobir, Jake Moses Najman, Gail Williams, Lane Strathearn, Alexandra Clavarino, Steve Kisely
This study investigates the association between exposure to prospectively-substantiated childhood maltreatment between 0 and 14 years of age and lifetime cannabis use, abuse and dependence reported at 21 years. Data were taken from 2526 (51.6% female) participants in the Mater Hospital-University of Queensland Study of Pregnancy, a pre-birth, prospective, cohort study. Prospectively-substantiated cases of childhood maltreatment, reported to the government child protection agencies between 0 and 14 years of age, were linked to CIDI DSM-IV self-report data from the 21-year follow-up...
June 9, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28618391/daily-level-associations-between-ptsd-and-cannabis-use-among-young-sexual-minority-women
#10
Emily R Dworkin, Debra Kaysen, Michele Bedard-Gilligan, Isaac C Rhew, Christine M Lee
INTRODUCTION: Sexual minority women have elevated trauma exposure and prevalence of posttraumatic stress disorder (PTSD) compared to heterosexual women and they are also more likely to use cannabis, although no research has examined relationships between PTSD and cannabis use in this population. Daily-level methodologies are necessary to examine proximal associations between PTSD and use. METHODS: This study included 90 trauma-exposed young adult women who identified as sexual minorities (34...
June 8, 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/28613973/the-association-of-cannabis-use-on-inpatient-psychiatric-hospital-outcomes
#11
Melanie Rylander, Helena R Winston, Haley Medlin, Madelyne Hull, Abraham Nussbaum
BACKGROUND: The associations between cannabis use and psychosis are well documented in numerous studies. There is a need to evaluate the impact of cannabis use on inpatient psychiatric utilization and outcomes. OBJECTIVES: To evaluate the impact of cannabis use on psychiatric hospital outcomes. METHODS: This study was conducted between April 20, 2015 and October 20, 2015. All patients (n = 120) admitted to Denver Health with psychotic symptoms were administered a urine toxicology screening testing for the presence of 11-nor-9-carboxy-Δ(9)-tetrahydrocannabinol (THC-COOH, the active metabolite of cannabis)...
June 14, 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/28600897/examination-of-cumulative-effects-of-early-adolescent-depression-on-cannabis-and-alcohol-use-disorder-in-late-adolescence-in-a-community-based-cohort
#12
Isaac C Rhew, Charles B Fleming, Ann Vander Stoep, Semret Nicodimos, Cheng Zheng, Elizabeth McCauley
BACKGROUND AND AIMS: Although they often co-occur, the longitudinal relationship between depression and substance use disorders during adolescence remains unclear. This study estimated the effects of cumulative depression during early adolescence (ages 13-15) on the likelihood of cannabis use disorder (CUD) and alcohol use disorder (AUD) at age 18. DESIGN: Prospective cohort study of youth assessed at least annually between 6(th) and 9(th) grade (~ age 12 to 15) and again at age 18...
June 10, 2017: Addiction
https://www.readbyqxmd.com/read/28600874/loose-regulation-of-medical-marijuana-programs-associated-with-higher-rates-of-adult-marijuana-use-but-not-cannabis-use-disorder
#13
Arthur Robin Williams, Julian Santaella-Tenorio, Christine M Mauro, Frances R Levin, Silvia S Martins
BACKGROUND AND AIMS: Most U.S. states have passed medical marijuana laws (MMLs), with great variation in program regulation impacting enrollment rates. We aimed to compare changes in rates of marijuana use, heavy use, and Cannabis Use Disorder across age groups while accounting for whether states enacted medicalized (highly regulated) or non-medical MML programs. DESIGN: Difference-in-differences estimates with time-varying state-level MML coded by program type (medicalized v...
June 10, 2017: Addiction
https://www.readbyqxmd.com/read/28600754/substance-use-disorder-treatment-following-clinician-initiated-discontinuation-of-long-term-opioid-therapy-resulting-from-an-aberrant-urine-drug-test
#14
Shannon M Nugent, Steven K Dobscha, Benjamin J Morasco, Michael I Demidenko, Thomas H A Meath, Joseph W Frank, Travis I Lovejoy
BACKGROUND: It is unclear whether substance use disorder (SUD) treatment is offered to, or utilized by, patients who are discontinued from long-term opioid therapy (LTOT) following aberrant urine drug tests (UDTs). OBJECTIVE: To describe the proportion of patients who were referred to, and engaged in, SUD treatment following LTOT discontinuation and to examine differences in SUD treatment referral and engagement based on the substances that led to discontinuation...
June 9, 2017: Journal of General Internal Medicine
https://www.readbyqxmd.com/read/28599214/prevalence-and-correlates-of-treatment-utilization-among-adults-with-cannabis-use-disorder-in-the-united-states
#15
Li-Tzy Wu, He Zhu, Paolo Mannelli, Marvin S Swartz
BACKGROUND: The increase in cannabis potency may have treatment implications for cannabis use disorder (CUD). Given the reported increase in prevalence of cannabis use among adults, there is a need to understand substance use treatment needs for CUD. METHODS: We examined demographics and behavioral health indicators of adults aged ≥18 years that met criteria for past-year CUD (n=10,943) in the 2005-2013 National Surveys on Drug Use and Health. We determined prevalence and correlates of past-year treatment use for alcohol/drug, any drug, and cannabis use related problems, to inform treatment efforts for CUD...
May 29, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28595088/the-relationship-between-cannabis-use-and-cortisol-levels-in-youth-at-ultra-high-risk-for-psychosis
#16
Emily E Carol, Robert L Spencer, Vijay A Mittal
Recent studies have posited a relationship between cannabis use and the biological stress system, but this critical relationship has not been evaluated during the ultra high-risk (UHR) period immediately preceding the onset of psychotic disorders. Salivary cortisol samples were collected on 46 UHR and 29 control adolescents; these individuals were assessed for current cannabis use with a urine panel and self-report. UHR participants where separated into two groups: Current Cannabis Use (UHR-CU) and No Current Cannabis Use (UHR-NC)...
May 30, 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/28590392/pilot-studies-examining-feasibility-of-substance-use-disorder-screening-and-treatment-linkage-at-urban-sexually-transmitted-disease-clinics
#17
Jan Gryczynski, Courtney D Nordeck, Shannon Gwin Mitchell, Kathleen R Page, Luke L Johnsen, Kevin E O'Grady, Robert P Schwartz
BACKGROUND: Sexually transmitted disease (STD) clinics provide critical public health services for screening and treatment of sexually transmitted infections throughout the United States. These settings serve high-risk populations, often on a walk-in basis, and may be promising venues for integrating substance use disorder (SUD) services. METHODS: We report findings from 2 pilot studies conducted at Baltimore City Health Department's STD clinics. The screening study characterized rates of SUDs among STD clinic patients...
June 5, 2017: Journal of Addiction Medicine
https://www.readbyqxmd.com/read/28586550/commentary-on-ostergaard-et-al-2017-evidence-of-an-association-between-cannabis-use-and-suicide-in-subjects-with-bipolar-disorder
#18
https://www.readbyqxmd.com/read/28580227/does-cannabis-composition-matter-differential-effects-of-delta-9-tetrahydrocannabinol-and-cannabidiol-on-human-cognition
#19
REVIEW
Marco Colizzi, Sagnik Bhattacharyya
PURPOSE OF REVIEW: The lack of clarity about the effect of cannabis use on cognition may be attributable to the considerable heterogeneity among studies in terms of cannabis composition. This article selectively reviews studies examining the distinctive effects of cannabinoids on human cognition, particularly those of delta-9-tetrahydrocannabinol (Δ9-THC) and cannabidiol (CBD). RECENT FINDINGS: Research indicates that ∆9-THC administration acutely impairs cognition, particularly memory and emotional processing...
2017: Current Addiction Reports
https://www.readbyqxmd.com/read/28576350/cannabinoids-in-attention-deficit-hyperactivity-disorder-a-randomised-controlled-trial
#20
Ruth E Cooper, Emma Williams, Seth Seegobin, Charlotte Tye, Jonna Kuntsi, Philip Asherson
Adults with ADHD describe self-medicating with cannabis, with some reporting a preference for cannabis over ADHD medications. A small number of psychiatrists in the US prescribe cannabis medication for ADHD, despite there being no evidence from randomised controlled studies. The EMA-C trial (Experimental Medicine in ADHD-Cannabinoids) was a pilot randomised placebo-controlled experimental study of a cannabinoid medication, Sativex Oromucosal Spray, in 30 adults with ADHD. The primary outcome was cognitive performance and activity level using the QbTest...
May 30, 2017: European Neuropsychopharmacology: the Journal of the European College of Neuropsychopharmacology
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