keyword
MENU ▼
Read by QxMD icon Read
search

hercules

keyword
https://www.readbyqxmd.com/read/28803462/structural-characterization-of-methylenedianiline-regioisomers-by-ion-mobility-and-mass-spectrometry-iii-maldi-spectra-of-2-ring-isomers
#1
Sarah M Stow, Tiffany M Crescentini, Jay G Forsythe, Jody C May, John A McLean, David M Hercules
Characterization of methylenedianiline (MDA) 2-ring isomers (2,2'-, 2,4'- and 4,4'-MDA) is reported using matrix assisted laser desorption/ionization-mass spectrometry (MALDI-MS), a common technique used for characterizing synthetic polymers. MDA is a precursor to methylene diphenyl diisocyanate (MDI) a hard block component in polyurethane (PUR) synthesis. This manuscript focuses on comparing MALDI results to those of our previous electrospray ionization-mass spectrometry (ESI-MS) studies. In ESI, 2-ring MDA isomers formed single unique [M+H]+ (199 Da) parent ions, whereas in MALDI each isomer shows significant formation of three precursor ions: [M-H]+ = 197 Da, [M...
August 13, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28797594/rare-endoparasitic-asteriomyzostomum-annelida-asteriomyzostomidae-from-japan-including-three-new-species-descriptions-and-their-phylogenetic-position-within-myzostomida
#2
Naoto Jimi, Takeya Moritaki, Hiroshi Kajihara
The rare myzostomid genus Asteriomyzostomum Jägersten, 1940 consists of two species, both parasitizing sea stars. The phylogenetic position of this genus among Myzostomida has not been previously shown using molecular data. In this study, three species of Asteriomyzostomum were collected from the Kumano Sea, Japan, and are described as A. jinshou sp. nov., A. monroeae sp. nov., and A. hercules sp. nov. Additional specimens of the genus Asteromyzostomum were also collected from the Kumano Sea and briefly reported as Asteromyzostomum sp...
August 7, 2017: Parasitology International
https://www.readbyqxmd.com/read/28686542/polyunsaturated-fatty-acids-and-endocannabinoids-in-health-and-disease
#3
Hércules Rezende Freitas, Alinny Rosendo Isaac, Renato Malcher-Lopes, Bruno Lourenço Diaz, Isis Hara Trevenzoli, Ricardo Augusto De Melo Reis
Polyunsaturated fatty acids (PUFAs) are lipid derivatives of omega-3 (docosahexaenoic acid, DHA, and eicosapentaenoic acid, EPA) or of omega-6 (arachidonic acid, ARA) synthesized from membrane phospholipids and used as a precursor for endocannabinoids (ECs). They mediate significant effects in the fine-tune adjustment of body homeostasis. Phyto- and synthetic cannabinoids also rule the daily life of billions worldwide, as they are involved in obesity, depression and drug addiction. Consequently, there is growing interest to reveal novel active compounds in this field...
July 7, 2017: Nutritional Neuroscience
https://www.readbyqxmd.com/read/28678925/gestational-protein-restriction-increases-cardiac-connexin-43-mrna-levels-in-male-adult-rat-offspring
#4
Kamila Fernanda Rossini, Camila Andrea de Oliveira, Hércules Jonas Rebelato, Marcelo Augusto Marreto Esquisatto, Rosana Catisti
Background: The dietary limitation during pregnancy influences the growth and development of the fetus and offspring and their health into adult life. The mechanisms underlying the adverse effects of gestational protein restriction (GPR) in the development of the offspring hearts are not well understood. Objectives: The aim of this study was to evaluate the effects of GPR on cardiac structure in male rat offspring at day 60 after birth (d60). Methods: Pregnant Wistar rats were fed a normal-protein (NP, 17% casein) or low-protein (LP, 6% casein) diet...
July 2017: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/28619069/social-determinants-of-depression-and-suicidal-behaviour-in-the-caribbean-a-systematic-review
#5
Catherine R Brown, Ian R Hambleton, Natasha Sobers-Grannum, Shawn M Hercules, Nigel Unwin, E Nigel Harris, Rainford Wilks, Marlene MacLeish, Louis Sullivan, Madhuvanti M Murphy
BACKGROUND: Depressive disorder is the largest contributor to years lived with disability in the Caribbean, adding 948 per 100,000 in 2013. Depression is also a major risk factor for suicidal behaviour. Social inequalities influence the occurrence of depression, yet little is known about the social inequalities of this condition in the Caribbean. In support of the 2011 Rio Political Declaration on addressing health inequities, this article presents a systematic review of the role of social determinants on depression and its suicidal behaviours in the Caribbean...
June 15, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28610076/reinstatement-of-i-spirostreptus-i-i-kandyanus-i-humbert-1865-and-deletion-of%C3%A2-i-thyropygus-i-i-allevatus-i-karsch-1881-and-i-sphaeropoeus-i-i-hercules-i-brandt-1833-in-the-checklist-of-sri-lankan-diplopoda
#6
H K S DE Zoysa, Kanishka D B Ukuwela, S Wickramasinghe, Anh D Nguyen, John Hollier
The Diplopoda have been studied for some 250 years, but until the later part of the nineteenth century most descriptions were rather cursory and neither the species concept nor type concept were well established (Hoffman 2009). Even for well-explored regions like Europe, the description of the Diplopoda saw a proliferation of synonyms (Enghoff 1976) while the complexity of Diplopoda systematics was severely underestimated until very recently (Brewer et al. 2012).
March 27, 2017: Zootaxa
https://www.readbyqxmd.com/read/28601386/detection-of-alk-and-kras-mutations-in-circulating-tumor-dna-of-patients-with-advanced-alk-positive-nsclc-with-disease-progression-during-crizotinib-treatment
#7
Paola Bordi, Marcello Tiseo, Eleonora Rofi, Iacopo Petrini, Giuliana Restante, Romano Danesi, Marzia Del Re
BACKGROUND: In patients with anaplastic lymphoma kinase (ALK)-positive non-small-cell lung cancer (NSCLC), disease progression occurs after a median of 9 to 10 months of crizotinib treatment. Several mechanisms of resistance have been identified and include ALK mutations and amplification or the activation of bypassing signaling pathways. Rebiopsy in NSCLC patients represents a critical issue and the analysis of circulating cell-free DNA (cfDNA) has a promising role for the identification of resistance mechanisms...
May 18, 2017: Clinical Lung Cancer
https://www.readbyqxmd.com/read/28600230/cytokine-and-chemokine-profile-changes-in-patients-with-lower-segment-lumbar-degenerative-spondylolisthesis
#8
Juraj Sutovsky, Martin Benco, Martina Sutovska, Michaela Kocmalova, Lenka Pappova, Juraj Miklusica, Andrej Frano, Egon Kurca
BACKGROUND: Lumbar degenerative spondylolisthesis (DS) develops as a result of inflammatory and remodeling processes in facet joints (FJs). Several inflammatory cytokines are involved in the osteoarthritic and remodeling changes that occur and in low-back and/or radicular pain, the most prevalent clinical symptom of disease. This study improves knowledge related to the roles that 27 cytokines, chemokines and growth factors play in the pathophysiology of lumbar DS. MATERIAL AND METHODS: Cytokine levels were examined using capture sandwich immunoassay using the Bio-Plex(®) 200 System and the Bio-PlexTM Human Cytokine Standard 27-Plex, Group I (Bio-Rad, Hercules, California, USA) separately in intervertebral discs (IVDs) and FJ bone tissue...
June 6, 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/28586698/multiscale-characterization-of-the-hierarchical-structure-of-dynastes-hercules-elytra
#9
Charles Roux-Pertus, Erwan Oliviero, Véronique Viguier, Frédéric Fernandez, Frédéric Maillot, Olivier Ferry, Solenne Fleutot, João F Mano, Franck Cleymand
Beetle elytra are thickened forewings, they are lightweight and tough to protect the hindwings without hindering flight capacities. Dynastes hercules elytra are known for their hygrochromic properties. However, the whole structure of the elytron remains to be characterized. Scanning Electron Microscopy (SEM), Transmission Electron Microscopy (TEM) and to our knowledge for the first time X-Ray tomography were undertaken on adult male Dynastes hercules to characterize their multi-scale structure. Trabeculae present a periodic arrangement over a short distance...
May 4, 2017: Micron: the International Research and Review Journal for Microscopy
https://www.readbyqxmd.com/read/28573491/p2x7-receptor-large-pore-signaling-in-avian-m%C3%A3-ller-glial-cells
#10
Robson X Faria, Hercules R Freitas, Ricardo A M Reis
ATP is a pleiotropic molecule that promotes extra- and intracellular signaling to regulate numerous functions. This nucleotide activates purine and pyrimidine receptors at the plasma membrane, categorized as ionotropic P2X or G-protein-coupled receptor (GPCR) P2Y receptors. P2X are ligand-gated ion channel receptors, expressed in both retinal neurons and Müller cells leading to neuron-glia communication, calcium waves and neurovascular coupling. However, how P2X pore is formed upon ATP activation and how signaling pathways regulates the complex is still a matter of controversy...
June 1, 2017: Journal of Bioenergetics and Biomembranes
https://www.readbyqxmd.com/read/28552867/an-unusual-case-of-sodium-channel-myotonia-with-transient-weakness-upon-initiating-movements-which-is-characteristic-in-becker-disease
#11
Junpei Yamamoto, Keiichi Hokkoku, Yuki Hatanaka, Shunichi Sakoda, Jun-Hui Yuan M D, Masahiro Sonoo
We reported a 32-year-old man who was a sporadic case of myotonic syndrome with muscle stiffness or transient weakness of limbs upon initiating movements after rest. On examination, he showed painless myotonia with warm-up phenomenon, Hercules-like hypertrophic musculature and myotonic discharges in EMG. The clinical findings resembled to those of Becker disease rather than Thomsen disease. But electrodiagnosis suggested sodium channel myotonia instead of chloride channelopathy. Genetic testing detected a novel missense mutation (p...
May 26, 2017: Rinshō Shinkeigaku, Clinical Neurology
https://www.readbyqxmd.com/read/28526460/semi-supervised-medical-entity-recognition-a-study-on-spanish-and-swedish-clinical-corpora
#12
Alicia Pérez, Rebecka Weegar, Arantza Casillas, Koldo Gojenola, Maite Oronoz, Hercules Dalianis
OBJECTIVE: The goal of this study is to investigate entity recognition within Electronic Health Records (EHRs) focusing on Spanish and Swedish. Of particular importance is a robust representation of the entities. In our case, we utilized unsupervised methods to generate such representations. METHODS: The significance of this work stands on its experimental layout. The experiments were carried out under the same conditions for both languages. Several classification approaches were explored: maximum probability, CRF, Perceptron and SVM...
July 2017: Journal of Biomedical Informatics
https://www.readbyqxmd.com/read/28503088/restoring-trail-induced-apoptosis-using-naturopathy-hercules-joins-hand-with-nature-to-triumph-over-lernaean-hydra
#13
REVIEW
Ammad Ahmad Farooqi, Cosmo Damiano Gadaleta, Girolamo Ranieri, Sundas Fayyaz, Ilaria Marech
Cancer is a multifaceted disease. Our deepened knowledge about genetic and biological mechanisms of cancer cells presents an opportunity to explore the inter-individual differences in the body's ability to metabolize and respond to different nutrients. It is becoming progressively more understandable that the deregulation of several signaling pathways and the alterations in apoptotic response are some of the major determinants that underpin carcinogenesis. Tumor necrosis factor-Related Apoptosis-Inducing Ligand (TRAIL)-mediated signaling has gained a remarkable appreciation because of its ability to selectively induce apoptosis in cancer cells leaving normal cells intact...
February 2017: Current Genomics
https://www.readbyqxmd.com/read/28459203/leptin-acts-on-neoplastic-behavior-and-expression-levels-of-genes-related-to-hypoxia-angiogenesis-and-invasiveness-in-oral-squamous-cell-carcinoma
#14
Eliane Macedo Sobrinho Santos, Talita Antunes Guimarães, Hércules Otacílio Santos, Lilian Mendes Borborema Cangussu, Sabrina Ferreira de Jesus, Carlos Alberto de Carvalho Fraga, Claudio Marcelo Cardoso, Sérgio Henrique Souza Santos, Alfredo Maurício Batista de Paula, Ricardo Santiago Gomez, André Luiz Sena Guimarães, Lucyana Conceição Farias
Leptin, one of the main hormones controlling energy homeostasis, has been associated with different cancer types. In oral cancer, its effect is not well understood. We investigated, through in vitro and in vivo assays, whether leptin can affect the neoplastic behavior of oral squamous cell carcinoma. Expression of genes possibly linked to the leptin pathway was assessed in leptin-treated oral squamous cell carcinoma cells and also in tissue samples of oral squamous cell carcinoma and oral mucosa, including leptin, leptin receptor, hypoxia-inducible factor 1-alpha, E-cadherin, matrix metalloproteinase-2, matrix metalloproteinase-9, Col1A1, Ki67, and mir-210...
May 2017: Tumour Biology: the Journal of the International Society for Oncodevelopmental Biology and Medicine
https://www.readbyqxmd.com/read/28435010/ribotypes-associated-with-clostridium-difficile-outbreaks-in-brazil-display-distinct-surface-protein-profiles
#15
Thais Gonçalves Ferreira, Hercules Moura, John R Barr, Regina M C Pilotto Domingues, Eliane de Oliveira Ferreira
Clostridium difficile is a spore-forming anaerobic intestinal pathogen that causes Clostridium difficile infection (CDI). C. difficile is the leading cause of toxin-mediated nosocomial antibiotic-associated diarrhea. The pathogenesis of CDI is attributed to two major virulence factors, TcdA and TcdB toxins, that cause the symptomatic infection. C. difficile also expresses a number of key proteins, including cell wall proteins (CWPs). S-layer proteins (SLPs) are CWPs that form a paracrystalline surface array that coats the surface of the bacterium...
June 2017: Anaerobe
https://www.readbyqxmd.com/read/28423786/prevalence-estimation-of-protected-health-information-in-swedish-clinical-text
#16
Aron Henriksson, Maria Kvist, Hercules Dalianis
Obscuring protected health information (PHI) in the clinical text of health records facilitates the secondary use of healthcare data in a privacy-preserving manner. Although automatic de-identification of clinical text using machine learning holds much promise, little is known about the relative prevalence of PHI in different types of clinical text and whether there is a need for domain adaptation when learning predictive models from one particular domain and applying it to another. In this study, we address these questions by training a predictive model and using it to estimate the prevalence of PHI in clinical text written (1) in different clinical specialties, (2) in different types of notes (i...
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28381227/social-determinants-of-breast-cancer-in-the-caribbean-a-systematic-review
#17
REVIEW
Catherine R Brown, Ian R Hambleton, Shawn M Hercules, Miriam Alvarado, Nigel Unwin, Madhuvanti M Murphy, E Nigel Harris, Rainford Wilks, Marlene MacLeish, Louis Sullivan, Natasha Sobers-Grannum
BACKGROUND: Breast cancer is the leading cause of cancer deaths among women in the Caribbean and accounts for >1 million disability adjusted life years. Little is known about the social inequalities of this disease in the Caribbean. In support of the Rio Political Declaration on addressing health inequities, this article presents a systematic review of evidence on the distribution, by social determinants, of breast cancer risk factors, frequency, and adverse outcomes in Caribbean women...
April 5, 2017: International Journal for Equity in Health
https://www.readbyqxmd.com/read/28380870/high-performance-refractive-index-sensor-based-on-low-q-factor-ring-resonators-and-fft-processing-of-wavelength-scanning-data
#18
Lefteris Gounaridis, Panos Groumas, Erik Schreuder, George Tsekenis, Athanasios Marousis, Rene Heideman, Hercules Avramopoulos, Christos Kouloumentas
We extend our previous simulation study and we present experimental results regarding our Fast Fourier Transform method for the calculation of the resonance shifts in biosensors based on micro-ring resonators (MRRs). For the simulation study, we use a system model with a tunable laser at 850 nm, an MRR with 1.5∙10<sup>4</sup> quality factor, and a detection system with 50 dB maximum signal-to-noise ratio, and investigate the impact on the system performance of factors like the number of the resonance peaks inside the scanning window, the wavelength dependence of the laser power, and the asymmetry of the transfer functions of the MRRs...
April 3, 2017: Optics Express
https://www.readbyqxmd.com/read/28333150/kaiso-depletion-attenuates-the-growth-and-survival-of-triple-negative-breast-cancer-cells
#19
Blessing I Bassey-Archibong, Lyndsay G A Rayner, Shawn M Hercules, Craig W Aarts, Anna Dvorkin-Gheva, Jonathan L Bramson, John A Hassell, Juliet M Daniel
Triple negative breast cancers (TNBC) are highly aggressive and lack specific targeted therapies. Recent studies have reported high expression of the transcription factor Kaiso in triple negative tumors, and this correlates with their increased aggressiveness. However, little is known about the clinical relevance of Kaiso in the growth and survival of TNBCs. Herein, we report that Kaiso depletion attenuates TNBC cell proliferation, and delays tumor onset in mice xenografted with the aggressive MDA-231 breast tumor cells...
March 23, 2017: Cell Death & Disease
https://www.readbyqxmd.com/read/28271628/zinc-oxide-3d-microstructures-as-an-antimicrobial-filler-content-for-composite-resins
#20
Hércules Bezerra Dias, Maria Inês Basso Bernardi, Matheus Aparecido Dos Santos Ramos, Tamara Carolina Trevisan, Taís Maria Bauab, Antônio Carlos Hernandes, Alessandra Nara de Souza Rastelli
The aim of this study was to evaluate the antibacterial activity of a composite resin modified by 3D zinc oxide (ZnO) microstructures and to verify possible alterations on its mechanical properties. ZnO was synthesized by hydrothermal approach and characterized by X-ray diffraction (XRD), surface area by Brunauer, Emmett and Teller (BET), Fourier transform infrared spectroscopy (FTIR) and Field emission scanning electron microscopy (FESEM). The minimum inhibitory concentrations of ZnO against Streptococcus mutans, Escherichia coli, Staphylococcus aureus, and Candida albicans were determinated...
March 8, 2017: Microscopy Research and Technique
keyword
keyword
119745
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"