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https://www.readbyqxmd.com/read/28655271/one-year-results-of-a-randomized-controlled-trial-on-radial-extracorporeal-shock-wave-treatment-with-predictors-of-pain-disability-and-return-to-work-in-patients-with-subacromial-pain-syndrome
#1
Elisabeth Kvalvaag, Cecilie Røe, Kaia B Engebretsen, Helene L Soberg, Niels G Juel, Erik Bautz-Holter, Leiv Sandvik, Jens I Brox
BACKGROUND: Radial extracorporeal Shock Wave Therapy (rESWT) is increasingly used to treat patients with subacromial pain syndrome despite conflicting evidence of its effectiveness. Better knowledge regarding prognostic factors may contribute to the improvement in treatment and prognosis for the patients. AIM: The first aim of this study was to evaluate the effect of rESWT in addition to supervised exercises in patients with subacromial pain syndrome after one year...
June 27, 2017: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/28655218/isolation-and-characterization-of-burkholderia-fungorum-gan-35-with-the-outstanding-ammonia-nitrogen-degrading-ability-from-the-tailings-of-rare-earth-element-mines-in-southern-jiangxi-china
#2
Ai-Juan Feng, Xi Xiao, Cong-Cong Ye, Xiao-Ming Xu, Qing Zhu, Jian-Ping Yuan, Yue-Hui Hong, Jiang-Hai Wang
The exploitation of rare-earth-element (REE) mines has resulted in severe ammonia nitrogen pollution and induced hazards to environments and human health. Screening microorganisms with the ammonia nitrogen-degrading ability provides a basis for bioremediation of ammonia nitrogen-polluted environments. In this study, a bacterium with the outstanding ammonia nitrogen-degrading capability was isolated from the tailings of REE mines in southern Jiangxi Province, China. This strain was identified as Burkholderia fungorum Gan-35 according to phenotypic and phylogenetic analyses...
December 2017: AMB Express
https://www.readbyqxmd.com/read/28655201/unplanned-reoperation-after-craniotomy-for-tumor-a-national-surgical-quality-improvement-program-analysis
#3
Hormuzdiyar H Dasenbrock, Sandra C Yan, Vamsi Chavakula, William B Gormley, Timothy R Smith, Elizabeth B Claus, Ian F Dunn
BACKGROUND: Reoperation has been increasingly utilized as a metric evaluating quality of care. OBJECTIVE: To evaluate the rate of, reasons for, and predictors of unplanned reoperation after craniotomy for tumor in a nationally accrued population. METHODS: Patients who underwent cranial tumor resection were extracted from the prospective National Surgical Quality Improvement Program registry (2012-2014). Multivariate logistic regression examined predictors of unplanned cranial reoperation...
June 26, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28655145/partitioned-learning-of-deep-boltzmann-machines-for-snp-data
#4
Moritz Hess, Stefan Lenz, Tamara J Blätte, Lars Bullinger, Harald Binder
Motivation: Learning the joint distributions of measurements, and in particular identification of an appropriate low-dimensional manifold, has been found to be a powerful ingredient of deep leaning approaches. Yet, such approaches have hardly been applied to single nucleotide polymorphism (SNP) data, probably due to the high number of features typically exceeding the number of studied individuals. Results: After a brief overview of how deep Boltzmann machines (DBMs), a deep learning approach, can be adapted to SNP data in principle, we specifically present a way to alleviate the dimensionality problem by partitioned learning...
June 26, 2017: Bioinformatics
https://www.readbyqxmd.com/read/28655127/depression-screening-by-physical-therapists-practices-beliefs-barriers
#5
Patricia Fay, Susan L Edmond, Julia K Baron, Michelle Joshi
BACKGROUND: Depression, a common comorbidity encountered in physical therapy (PT) practice, negatively impacts outcomes. There is limited knowledge of PT practice patterns relative to screening for depression. OBJECTIVE: Objectives were to describe beliefs regarding depression, and identify practice patterns and perceived barriers regarding screening for depression among APTA Board Certified Orthopedic Clinical Specialist (OCS) PTs. METHODS: Surveys were distributed to all PT OCSs in the US; 416 responses were analyzed...
June 2, 2017: Journal of Back and Musculoskeletal Rehabilitation
https://www.readbyqxmd.com/read/28655068/potential-impact-of-screening-for-fatty-liver-disease-by-transient-elastography-with-liver-stiffness-and-controlled-attenuation-parameter-measurements-a-pilot-study
#6
Moritz Peiseler, Anna Creutzfeldt, Insa Cassens, Claudia Glaubke, Claudia Kroll, Ansgar W Lohse, Christina Weiler-Normann
Background The prevalence of chronic liver diseases is high in developed countries, and the leading causes are amenable to prevention. The German Lebertag is to increase awareness of the burden of chronic liver diseases in the general public. We performed a pilot study using transient elastography with liver stiffness measurement (LSM) and the controlled attenuation parameter (CAP) as a screening tool for previously unrecognized liver diseases. Patients and methods LSM and CAP was performed in 60 individuals, and participants filled in a questionnaire reporting basic characteristics and past medical history...
June 27, 2017: Zeitschrift Für Gastroenterologie
https://www.readbyqxmd.com/read/28655061/outcomes-in-women-with-cytology-showing-atypical-squamous-cells-of-undetermined-significance-with-vs-without-human-papillomavirus-testing
#7
Jack Cuzick, Orrin Myers, Ji-Hyun Lee, Yang Shi, Julia C Gage, William C Hunt, Michael Robertson, Cosette M Wheeler
Importance: Little is known about the long-term yield of high-grade cervical intraepithelial neoplasia (CIN) and the influence on biopsy and treatment rates of human papillomavirus (HPV) triage of cytology showing atypical squamous cells of undetermined significance (hereafter ASC-US cytology). Objective: To examine 5-year outcomes after ASC-US cytology with vs without HPV testing. Design, Setting, and Participants: In this observational study, all cervical cytology and HPV testing reports from January 1, 2007, to December 31, 2012, were obtained for women throughout New Mexico and linked to pathology reports...
June 22, 2017: JAMA Oncology
https://www.readbyqxmd.com/read/28655054/label-free-tissue-scanner-for-colorectal-cancer-screening
#8
Mikhail E Kandel, Shamira Sridharan, Jon Liang, Zelun Luo, Kevin Han, Virgilia Macias, Anish Shah, Roshan Patel, Krishnarao Tangella, Andre Kajdacsy-Balla, Grace Guzman, Gabriel Popescu
No abstract text is available yet for this article.
June 1, 2017: Journal of Biomedical Optics
https://www.readbyqxmd.com/read/28655029/breast-cancer-screening-with-mammography-plus-ultrasonography-or-magnetic-resonance-imaging-in-women-50-years-or-younger-at-diagnosis-and-treated-with-breast-conservation-therapy
#9
Nariya Cho, Wonshik Han, Boo-Kyung Han, Min Sun Bae, Eun Sook Ko, Seok Jin Nam, Eun Young Chae, Jong Won Lee, Sung Hun Kim, Bong Joo Kang, Byung Joo Song, Eun-Kyung Kim, Hee Jung Moon, Seung Il Kim, Sun Mi Kim, Eunyoung Kang, Yunhee Choi, Hak Hee Kim, Woo Kyung Moon
Importance: Younger women (aged ≤50 years) who underwent breast conservation therapy may benefit from breast magnetic resonance imaging (MRI) screening as an adjunct to mammography. Objective: To prospectively determine the cancer yield and tumor characteristics of combined mammography with MRI or ultrasonography screening in women who underwent breast conservation therapy for breast cancers and who were 50 years or younger at initial diagnosis. Design, Setting, and Participants: This multicenter, prospective, nonrandomized study was conducted from December 1, 2010, to January 31, 2016, at 6 academic institutions...
June 22, 2017: JAMA Oncology
https://www.readbyqxmd.com/read/28655027/zolpidem-for-the-treatment-of-neurologic-disorders-a-systematic-review
#10
Martin N Bomalaski, Edward S Claflin, Whitney Townsend, Mark D Peterson
Importance: Given its selective action on the ω1 subtype of the γ-aminobutyric acid A receptor, zolpidem tartrate presents a potential treatment mechanism for other neurologic disorders. Objective: To synthesize studies that used zolpidem to treat neurologic disorders. Evidence Review: Eligibility criteria included any published English-language article that examined the use of zolpidem for noninsomnia neurologic disorders in humans for all dates up to March 20, 2015...
June 26, 2017: JAMA Neurology
https://www.readbyqxmd.com/read/28654989/risk-of-primary-tumor-sidedness-as-a-criterion-for-screening-diagnostic-colonoscopy-and-surveillance-intervals-reply
#11
Gianluca Tomasello, Fausto Petrelli, Sandro Barni
No abstract text is available yet for this article.
June 22, 2017: JAMA Oncology
https://www.readbyqxmd.com/read/28654987/women-s-awareness-and-perceived-importance-of-the-harms-and-benefits-of-mammography-screening-results-from-a-2016-national-survey
#12
Jiani Yu, Rebekah H Nagler, Erika Franklin Fowler, Karla Kerlikowske, Sarah E Gollust
No abstract text is available yet for this article.
June 26, 2017: JAMA Internal Medicine
https://www.readbyqxmd.com/read/28654934/risk-of-primary-tumor-sidedness-as-a-criterion-for-screening-diagnostic-colonoscopy-and-surveillance-intervals
#13
Martin C S Wong, John C T Wong
No abstract text is available yet for this article.
June 22, 2017: JAMA Oncology
https://www.readbyqxmd.com/read/28654889/methylomics-of-nitroxidative-stress-on-precancerous-cells-reveals-dna-methylation-alteration-at-the-transition-from-in-situ-to-invasive-cervical-cancer
#14
Po-Hsuan Su, Yao-Wen Hsu, Rui-Lan Huang, Yu-Chun Weng, Hui-Chen Wang, Yu-Chih Chen, Yueh-Ju Tsai, Chiou-Chung Yuan, Hung-Cheng Lai
Epigenetic dysregulation is important in cervical cancer development, but the underlying mechanism is largely unknown. Increasing evidence indicates that DNA methylation is sensitive to changes in microenvironmental factors, such as nitric oxide (NO) in the chronic inflammatory cervix. However, the epigenomic effects of NO in cancer have not been investigated. In this study, we explored the methylomic effects of nitroxidative stress in HPV-immortalized precancerous cells. Chronic NO exposure promoted the acquisition of malignant phenotypes such as cell growth, migration, invasion, and anchorage-independent growth...
June 6, 2017: Oncotarget
https://www.readbyqxmd.com/read/28654878/development-of-a-semi-quantitative-risk-assessment-model-for-evaluating-environmental-threat-posed-by-the-three-first-eu-watch-list-pharmaceuticals-to-urban-wastewater-treatment-plants-an-irish-case-study
#15
Alexandre Tahar, Erin Jo Tiedeken, Eoghan Clifford, Enda Cummins, Neil Rowan
Contamination of receiving waters with pharmaceutical compounds is of pressing concern. This constitutes the first study to report on the development of a semi-quantitative risk assessment (RA) model for evaluating the environmental threat posed by three EU watch list pharmaceutical compounds namely, diclofenac, 17-beta-estradiol and 17-alpha-ethinylestradiol, to aquatic ecosystems using Irish data as a case study. This RA model adopts the Irish Environmental Protection Agency Source-Pathway-Receptor concept to define relevant parameters for calculating low, medium or high risk score for each agglomeration of wastewater treatment plant (WWTP), which include catchment, treatments, operational and management factors...
June 24, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28654858/reference-values-of-lithium-in-postmortem-femoral-blood
#16
Carl Söderberg, Emma Wernvik, Anna K Jönsson, Henrik Druid
INTRODUCTION: The main recipients of lithium, people diagnosed with bipolar disorder, show an increased mortality in both natural and unnatural causes of death. Based on international data persons diagnosed with bipolar disorder comprise 2.3-9.6% of all suicidal deaths. In cases of suicide among those suffering from bipolar disorder, 17-53% are due to fatal intoxications. Diagnosing fatal intoxications is often challenging, particularly when the reference information needed to interpret the concentration of a drug is lacking or scarce...
June 15, 2017: Forensic Science International
https://www.readbyqxmd.com/read/28654845/alcohol-related-cognitions-in-children-aged-2-10-and-how-they-are-shaped-by-parental-alcohol-use-a-systematic-review
#17
REVIEW
Carmen Voogt, Miriam Beusink, Marloes Kleinjan, Roy Otten, Rutger Engels, Koen Smit, Emmanuel Kuntsche
BACKGROUND: This systematic review aims to summarize the evidence of the impact of parental alcohol use on the acquisition of children's alcohol-related cognitions (alcohol-related knowledge, alcohol-related norms, alcohol expectancies) in the developmental period from age two to ten. METHODS: A computer-assisted systematic literature search was performed in PubMed, PsychINFO, ERIC, and EMBASE. Overall, 20 out of the 3406 unique articles identified in the first screening were included...
June 1, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28654818/high-throughput-screening-of-myxoid-liposarcoma-cell-lines-survivin-is-essential-for-tumor-growth
#18
Marieke A de Graaff, Shruti Malu, Irma Guardiola, Alwine B Kruisselbrink, Yvonne de Jong, Willem E Corver, H Gelderblom, Patrick Hwu, Torsten O Nielsen, Alexander J Lazar, Neeta Somaiah, Judith V M G Bovée
Myxoid liposarcoma (MLS) is a soft tissue sarcoma characterized by a recurrent t(12;16) translocation. Although tumors are initially radio- and chemosensitive, the management of inoperable or metastatic MLS can be challenging. Therefore, our aim was to identify novel targets for systemic therapy. We performed an in vitro high-throughput drug screen using three MLS cell lines (402091, 1765092, DL-221), which were treated with 273 different drugs at four different concentrations. Cell lines and tissue microarrays were used for validation...
June 24, 2017: Translational Oncology
https://www.readbyqxmd.com/read/28654767/melanoma-metastasis-to-the-mandible-case-report-and-comprehensive-literature-review
#19
Peter D Cervenka, Leonel Perez, Daniel E Perez, Bradley Jones
With the incidence of melanoma increasing yearly, there is a need for heightened awareness of its metastatic potential and for screening with appropriate referral for identification of pre-metastatic lesions. Melanoma has a 16- to 25-month period to metastasize from a localized disease to one with a median survival no longer than 12 months once metastasis occurs. Nearly one third of oral metastases are found to be the first indication of occult malignancy from a distant site. This report describes the case of a 54-year-old woman with a longstanding undiagnosed acral lentiginous melanoma with metastasis to the maxillofacial region...
June 1, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28654758/looking-into-a-whale-s-heart-investigating-a-genetic-basis-for-cardiomyopathy-in-a-non-model-species
#20
Amelia Viricel, Patricia E Rosel
Understanding the pathogenesis of complex diseases can benefit from multi-species comparative studies. Yet these studies rarely include natural populations of non-model species. Here, we focused on the cause of a heart muscle disease, cardiomyopathy (CM), affecting multiple mammalian species including humans, cats, dogs, and certain species of whales. Mutations in genes coding for sarcomeric proteins have been identified as a leading cause for CM in humans, and some were also revealed to be responsible for CM in cats...
June 27, 2017: Genome Génome / Conseil National de Recherches Canada
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