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Dynamic contrasted enhance MRI

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https://www.readbyqxmd.com/read/28733632/3d-anatomical-and-perfusion-mri-for-longitudinal-evaluation-of-biomaterials-for-bone-regeneration-of-femoral-bone-defect-in-rats
#1
Emeline J Ribot, Clement Tournier, Rachida Aid-Launais, Neha Koonjoo, Hugo Oliveira, Aurelien J Trotier, Sylvie Rey, Didier Wecker, Didier Letourneur, Joelle Amedee Vilamitjana, Sylvain Miraux
Magnetic Resonance Imaging (MRI) appears as a good surrogate to Computed Tomography (CT) scan as it does not involve radiation. In this context, a 3D anatomical and perfusion MR imaging protocol was developed to follow the evolution of bone regeneration and the neo-vascularization in femoral bone defects in rats. For this, three different biomaterials based on Pullulan-Dextran and containing either Fucoidan or HydroxyApatite or both were implanted. In vivo MRI, ex vivo micro-CT and histology were performed 1, 3 and 5 weeks after implantation...
July 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28733222/molecular-classification-of-hepatocellular-adenoma-in-clinical-practice
#2
REVIEW
Jean-Charles Nault, Valérie Paradis, Daniel Cherqui, Valérie Vilgrain, Jessica Zucman-Rossi
Incidental liver lesion depicted on preoperative imaging for bariatric surgery (BMI = 42) in a 34 year-old woman with oral contraceptive use of 15 years, normal blood liver tests and high CRP (11 mg/L, Nl <6). MRI showed a 6 cm liver nodule in segment V close to the gallbladder. The nodule was moderately hyperintense on T1 (in-phase) and showed a marked and heterogeneous drop in signal intensity on opposedphase sequence suggesting the presence of fat. On T2, the nodule was heterogeneous, hyperintense at the periphery and hypointense in most of the central part...
July 18, 2017: Journal of Hepatology
https://www.readbyqxmd.com/read/28727225/intact-blood-brain-barrier-during-spontaneous-attacks-of-migraine-without-aura-a-3t-dce-mri-study
#3
F M Amin, A Hougaard, S P Cramer, C E Christensen, F Wolfram, H B W Larsson, M Ashina
BACKGROUND AND PURPOSE: The integrity of the blood-brain barrier (BBB) has been questioned in migraine, but BBB permeability has never been investigated during spontaneous migraine attacks. In the present study, BBB permeability during spontaneous attacks of migraine without aura was investigated compared to an interictal state. METHODS: Seventy-four patients suffering from migraine without aura were recruited to participate in this cross-sectional dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) study...
July 20, 2017: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/28727185/automation-of-pattern-recognition-analysis-of-dynamic-contrast-enhanced-mri-data-to-characterize-intratumoral-vascular-heterogeneity
#4
SoHyun Han, Radka Stoyanova, Hansol Lee, Sean D Carlin, Jason A Koutcher, HyungJoon Cho, Ellen Ackerstaff
PURPOSE: To automate dynamic contrast-enhanced MRI (DCE-MRI) data analysis by unsupervised pattern recognition (PR) to enable spatial mapping of intratumoral vascular heterogeneity. METHODS: Three steps were automated. First, the arrival time of the contrast agent at the tumor was determined, including a calculation of the precontrast signal. Second, four criteria-based algorithms for the slice-specific selection of number of patterns (NP) were validated using 109 tumor slices from subcutaneous flank tumors of five different tumor models...
July 20, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28725592/is-contrast-enhancement-needed-for-diagnostic-prostate-mri
#5
REVIEW
Michele Scialpi, Valeria Rondoni, Maria Cristina Aisa, Eugenio Martorana, Alfredo D'Andrea, Corrado Maria Malaspina, Agostino Orlandi, Giorgio Galassi, Emanuele Orlandi, Pietro Scialpi, Michele Dragone, Diego Palladino, Annalisa Simeone, Michele Amenta, Giampaolo Bianchi
Prostate Imaging Reporting and Data System version 2 (PI-RADS v2) provides clinical guidelines for multiparametric magnetic resonance imaging (mpMRI) [T2-weighted imaging (T2WI), diffusion-weighted imaging (DWI) and dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI)] of prostate. However, DCE-MRI seems to show a limited contribution in prostate cancer (PCa) detection and management. In our experience, DCE-MRI, did not show significant change in diagnostic performance in addition to DWI and T2WI [biparametric MRI (bpMRI)] which represent the predominant sequences to detect suspected lesions in peripheral and transitional zone (TZ)...
June 2017: Translational Andrology and Urology
https://www.readbyqxmd.com/read/28725576/cost-consideration-in-utilization-of-multiparametric-magnetic-resonance-imaging-in-prostate-cancer
#6
REVIEW
Ryan Hutchinson, Yair Lotan
The screening, evaluation and management of prostate cancer changed significantly in the last decade. The recommendations regarding prostate cancer screening continue to evolve with new revelations about existing data sets and longer followup of landmark trials. Robotics has gained the vast majority of the marketplace for surgically managed prostate cancer in rapid fashion. The need for intervention in low risk prostate cancer has been closely examined and more men are being expectantly managed than ever before...
June 2017: Translational Andrology and Urology
https://www.readbyqxmd.com/read/28723741/characterization-of-small-%C3%A2-3%C3%A2-cm-hepatic-lesions-with-atypical-enhancement-feature-and-hypointensity-in-hepatobiliary-phase-of-gadoxetic-acid-enhanced-mri-in-cirrhosis-a-stard-compliant-article
#7
Seung Kak Shin, Yun Soo Kim, Seung Joon Choi, Young Sup Shim, Dong Hae Jung, Oh Sang Kwon, Duck Joo Choi, Ju Hyun Kim
It is difficult to characterize the nodular lesions in cirrhotic liver if typical enhancement pattern is not present on dynamic contrast-enhanced imagings. Although the signal intensity of the hepatobiliary phase in gadoxetic acid-enhanced magnetic resonance imaging (MRI) is helpful for characterization of the lesions, some dysplastic nodules may also exhibit low signal intensity in the hepatobiliary phase. We aimed to assess the usefulness of gadoxetic acid (Gd-EOB-DTPA)-enhanced MRI including diffusion-weighted imaging (DWI) for differentiation between atypical small hepatocellular carcinomas (HCCs) and dysplastic nodules showing low signal intensity (SI) in the hepatobiliary phase, and to evaluate the MRI findings in determining the histological grade of atypical HCCs in patients with cirrhosis...
July 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28721448/-pi-rads-2-0-for-prostate-mri
#8
T Franiel, M Röthke
The PI-RADS 2.0 classification was established by an international collaboration of the European Society of Urogenital Radiology (ESUR), the American College of Radiology (ACR), and AdMetech Foundation to globally standardize the acquisition and interpretation of multiparametric prostate magnetic resonance imaging (MRI). The PI-RADS 2.0 aims to improve the detection, localization, staging and risk stratification of patients with suspected or histologically confirmed prostate cancer. Suspicious areas on T2-weighted (T2w) MRI, diffusion-weighted MRI (DWI) and dynamic contrast-enhanced MRI (DCE-MRI) were assessed for the presence of a clinically significant prostate cancer with scale from 1 to 5 with 5 being most likely to represent clinically significant prostate cancer...
July 18, 2017: Der Radiologe
https://www.readbyqxmd.com/read/28720413/multiparametric-magnetic-resonance-imaging-of-the-prostate-for-tumour-detection-and-local-staging-imaging-in-1-5t-and-histopathologic-correlation
#9
Dimitra Loggitsi, Anastasios Gyftopoulos, Nikolaos Economopoulos, Aikaterini Apostolaki, Theodoros Kalogeropoulos, Anastasios Thanos, Efthimia Alexopoulou, Nikolaos L Kelekis
PURPOSE: The study sought to prospectively evaluate which technique among T2-weighted images, dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI), diffusion-weighted (DW) MRI, or a combination of the 2, is best suited for prostate cancer detection and local staging. METHODS: Twenty-seven consecutive patients with biopsy-proven adenocarcinoma of the prostate underwent MRI on a 1.5T scanner with a surface phased-array coil prior radical prostatectomy...
July 15, 2017: Canadian Association of Radiologists Journal, Journal L'Association Canadienne des Radiologistes
https://www.readbyqxmd.com/read/28712703/role-of-semi-quantitative-dynamic-contrast-enhanced-mr-imaging-in-characterization-and-grading-of-prostate-cancer
#10
See Hyung Kim, Mi Sun Choi, Mi Jung Kim, Young Hwan Kim, Seung Hyun Cho
OBJECTIVE: The study retrospectively assessed the diagnostic value of semi-quantitative dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI) in characterization and grading of prostate cancer, with correlation to histopathological analysis. MATERIALS AND METHODS: 161 consecutive patients with prostate cancer underwent DCE MRI. 430 lesions, including 200 cancers with Gleason grade (GG) of 6 (n=25), 7 (n=112) and 8 or higher (n=63); 80 benign hyperplasia; and 150 healthy tissues were assessed using a histology-MRI correlation...
July 6, 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28709889/dynamic-contrast-enhanced-mri-improves-classification-of-prostate-lesions-a-study-of-pathologic-outcomes-on-targeted-prostate-biopsy
#11
Sasha C Druskin, Ryan Ward, Andrei S Purysko, Allen Young, Jeffrey J Tosoian, Kamyar Ghabili, Darian Andreas, Eric Klein, Ashley E Ross, Katarzyna J Macura
PURPOSE: PIRADSv2 stipulates that dynamic-contrast-enhanced-imaging (DCE) be used to classify diffusion-weighted-imaging (DWI) score 3 (DWI3) peripheral-zone (PZ) lesions as PIRADS score 3 (PIRADS3; DCE-) or PIRADS4 (DCE+). However, it is unknown if DCE separates lesions into clinically-meaningful pathologic groups. We examined whether use of DCE improves detection of clinically-significant cancer. MATERIALS & METHODS: We identified patients without a prior diagnosis of prostate cancer undergoing multiparametric-MRI-transrectal-ultrasound fusion targeted-biopsy of PZ DWI3 or DWI4 lesions...
July 11, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28707958/gadofosveset-enhanced-thoracic-mr-venography-a-comparative-study-evaluating-steady-state-imaging-versus-conventional-first-pass-time-resolved-dynamic-imaging
#12
Teik C See, Andrew J Patterson, Nicholas J Hilliard, Ed Soh, Andrew P Winterbottom, Ilse Patterson, Richard A Parker, Martin J Graves, David J Lomas
Background Dedicated blood-pool contrast agents combined with optimal angiographic protocols could improve the diagnostic accuracy of thoracic magnetic resonance angiography (MRA). Purpose To assess the clinical utility of Gadofesveset-enhanced imaging and compare an optimized steady-state (SS) sequence against conventional first-pass dynamic multi-phase (DMP) imaging. Material and Methods Twenty-nine patients (17 men, 12 women; mean age = 42.7, age range = 18-72 years) referred for MR thoracic venography were recruited...
January 1, 2017: Acta Radiologica
https://www.readbyqxmd.com/read/28707546/a-computer-aided-diagnosis-cad-scheme-for-pretreatment-prediction-of-pathological-response-to-neoadjuvant-therapy-using-dynamic-contrast-enhanced-mri-texture-features
#13
Valentina Giannini, Simone Mazzetti, Agnese Marmo, Filippo Montemurro, Daniele Regge, Laura Martincich
OBJECTIVES: To assess whether a computer aided diagnosis (CAD) system can predict pathological response (pCR) to neoadjuvant chemotherapy (NAC) prior to treatment using texture features. MATERIALS AND METHODS: Response to treatment of 44 patients was defined according to the histopatology of resected tumour and extracted axillary nodes in two ways: a) pCR+ (Smith's grade=5) vs pCR- (Smith's grade<5); b) pCRN+ (pCR+ and absence of residual lymph node metastases) vs pCRN-...
July 14, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28707311/dynamic-contrast-enhanced-mri-of-the-patellar-bone-how-to-quantify-perfusion
#14
Dirk H J Poot, Rianne A van der Heijden, Marienke van Middelkoop, Edwin H G Oei, Stefan Klein
PURPOSE: To identify the optimal combination of pharmacokinetic model and arterial input function (AIF) for quantitative analysis of blood perfusion in the patellar bone using dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI). MATERIALS AND METHODS: This method design study used a random subset of five control subjects from an Institutional Review Board (IRB)-approved case-control study into patellofemoral pain, scanned on a 3T MR system with a contrast-enhanced time-resolved imaging of contrast kinetics (TRICKS) sequence...
July 14, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28702787/multiparametric-magnetic-resonance-imaging-for-transition-zone-prostate-cancer-essential-findings-limitations-and-future-directions
#15
REVIEW
Sara Lewis, Cecilia Besa, Ally Rosen, Ardeshir R Rastinehad, Sahar Semann, Stephanie Hectors, Bachir Taouli
OBJECTIVE: Review the multiparametric MRI (mpMRI) findings of transition zone (TZ) prostate cancer (PCa) using T2-weighted imaging (T2WI), diffusion-weighted imaging (DWI), and dynamic contrast-enhanced (DCE) MRI and to integrate mpMRI findings with clinical history, laboratory values, and histopathology. CONCLUSION: TZ prostate tumors are challenging to detect clinically and at MRI. mpMRI using the combination of sequences has the potential to improve accuracy of TZ cancer detection and staging...
July 12, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/28698942/mri-of-the-scrotum-recommendations-of-the-esur-scrotal-and-penile-imaging-working-group
#16
Athina C Tsili, Michele Bertolotto, Ahmet Tuncay Turgut, Vikram Dogra, Simon Freeman, Laurence Rocher, Jane Belfield, Michal Studniarek, Alexandra Ntorkou, Lorenzo E Derchi, Raymond Oyen, Parvati Ramchandani, Mustafa Secil, Jonathan Richenberg
OBJECTIVES: The Scrotal and Penile Imaging Working Group (SPI-WG) appointed by the board of the European Society of Urogenital Radiology (ESUR) has produced recommendations for magnetic resonance imaging (MRI) of the scrotum. METHODS: The SPI-WG searched for original and review articles published before September 2016 using the Pubmed and Medline databases. Keywords used were 'magnetic resonance imaging', 'testis or testicle or testicular', 'scrotum', 'intratesticular', 'paratesticular', 'extratesticular' 'diffusion-weighted', 'dynamic MRI'...
July 11, 2017: European Radiology
https://www.readbyqxmd.com/read/28695453/renal-epithelioid-angiomyolipoma-mri-findings
#17
Yan Zhong, Yanguang Shen, Jingjing Pan, Yingwei Wang, Yunxia An, Aitao Guo, Lu Ma, Huiyi Ye, Haiyi Wang
PURPOSE: To retrospectively analyze the MR imaging presentation of renal epithelioid angiomyolipoma (EAML). METHODS: Retrospective analysis revealed 12 subjects with histologically proven renal EAML who underwent preoperative MRI at our institution between January 2009 and June 2016. Two radiologists reviewed the images in consensus, describing MR imaging features including size, location, growth pattern, signal intensity of tumor, and dynamic enhancement pattern...
July 10, 2017: La Radiologia Medica
https://www.readbyqxmd.com/read/28695356/what-are-the-differentiating-clinical-and-mri-features-of-enchondromas-from-low-grade-chondrosarcomas
#18
Hassan Douis, M Parry, S Vaiyapuri, A M Davies
OBJECTIVES: To evaluate the role of clinical assessment, conventional and dynamic contrast-enhanced MRI in differentiating enchondromas from chondrosarcomas of long bone. METHODS: The following clinical and MRI findings were assessed: age, gender, pain, pain attributable to lesion, tumour location, tumour length, presence, depth of endosteal scalloping, bone marrow oedema, soft tissue oedema, cortical destruction, periosteal reaction, bone expansion, macroscopic fat, calcification, soft tissue mass, haemorrhage, dynamic contrast-enhanced MRI...
July 10, 2017: European Radiology
https://www.readbyqxmd.com/read/28693449/multiparametric-magnetic-resonance-imaging-in-mucosal-primary-head-and-neck-cancer-a-prospective-imaging-biomarker-study
#19
Christopher N Rumley, Mark T Lee, Lois Holloway, Robba Rai, Myo Min, Dion Forstner, Allan Fowler, Gary Liney
BACKGROUND: Radical radiotherapy, with or without concomitant chemotherapy forms the mainstay of organ preservation approaches in mucosal primary head and neck cancer. Despite technical advances in cancer imaging and radiotherapy administration, a significant proportion of patients fail to achieve a complete response to treatment. For those patients who do achieve a complete response, acute and late toxicities remain a cause of morbidity. A critical need therefore exists for imaging biomarkers which are capable of informing patient selection for both treatment intensification and de-escalation strategies...
July 10, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28693225/dynamic-mri-follow-up-of-radiation-encephalopathy-in-the-temporal-lobe-following-nasopharyngeal-carcinoma-radiotherapy
#20
Xiaofeng Zhou, Xiaofang Liao, Xiaoqiu Ren, Kewei Xiang, Qiongge Hu, Minming Zhang, Huijuan He, Li Shen, Qichun Wei
The natural course of radiation encephalopathy following nasopharyngeal carcinoma (NPC) radiotherapy remains poorly understood. The present study aimed to investigate the magnetic resonance imaging (MRI) characteristics and evolution of radiation encephalopathy. A series of 162 follow-up MRI examinations from 68 NPC patients with radiation encephalopathy in the temporal lobes were analyzed retrospectively. Each component of radiation encephalopathy was defined as follows: i) contrast enhanced lesions were enhanced lesions on contrast enhanced T1-weighted images (T1WI); ii) white matter lesions were lesions of homogeneous hyperintensity on T2-weighted images (T2WI) and hypointensity on T1WI; iii) cysts were round or oval well-defined lesions of hyperintensity on T2WI; iv) hemosiderin deposition were nodular or annular hypointense lesions with lower hypointense than normal white matter on both T1WI and T2WI; v) gray matter lesions were defined as disruption or erosion of hyperintensity in the cortex on T2WI...
July 2017: Oncology Letters
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