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role of diffusion MRI in diagnosis of liver metastases

Agnes Watanabe, Miguel Ramalho, Mamdoh AlObaidy, Hye Jin Kim, Fernanda G Velloni, Richard C Semelka
Noninvasive imaging has become the standard for hepatocellular carcinoma (HCC) diagnosis in cirrhotic livers. In this review paper, we go over the basics of MR imaging in cirrhotic livers and describe the imaging appearance of a spectrum of hepatic nodules marking the progression from regenerative nodules to low- and high-grade dysplastic nodules, and ultimately to HCCs. We detail and illustrate the typical imaging appearances of different types of HCC including focal, multi-focal, massive, diffuse/infiltrative, and intra-hepatic metastases; with emphasis on the diagnostic value of MR in imaging these lesions...
March 27, 2015: World Journal of Hepatology
Maka Kekelidze, Luigia D'Errico, Michele Pansini, Anthony Tyndall, Joachim Hohmann
In the last 10 years the mortality rate of colorectal cancer (CRC) has decreased by more than 20% due to the rising developments in diagnostic techniques and optimization of surgical, neoadjuvant and palliative therapies. Diagnostic methods currently used in the evaluation of CRC are heterogeneous and can vary within the countries and the institutions. This article aims to discuss in depth currently applied imaging modalities such as virtual computed tomography colonoscopy, endorectal ultrasound, computed tomography (CT) and magnetic resonance imaging (MRI) in the diagnosis of CRC...
December 14, 2013: World Journal of Gastroenterology: WJG
Sukru Mehmet Erturk, Tomoaki Ichikawa, Emel Kaya, Ozge Yapici, Alper Ozel, Abdullah Soydan Mahmutoglu, Muzaffer Basak
BACKGROUND: Although diffusion-weighted magnetic resonance imaging imaging (DW-MRI) is commonly used to characterize hepatic lesions, the literature is sparse about the use of MR diffusion tensor imaging (DTI) in this regard. By using DTI, one is able to obtain not only apparent diffusion coefficients (ADCs) but also fractional anisotropy (Fa) values. PURPOSE: To evaluate DTI using ADC and Fa values in the imaging of hepatic cysts, hemangiomas, and metastases. MATERIAL AND METHODS: Sixty-six patients with 77 lesions were examined with DTI...
July 2014: Acta Radiologica
Hersh Chandarana, Bachir Taouli
Liver metastases are the most frequently encountered malignant liver lesions in the Western countries. Accurate diagnosis of liver metastases is essential for appropriate management of these patients. Multiple imaging modalities, including ultrasound, CT, positron emission tomography, and MRI, are available for the evaluation of patients with suspected or known liver metastases. Contrast-enhanced MRI has a high accuracy for detection and characterization of liver lesions. Additionally, diffusion-weighted MRI (DWI) has been gaining increasing attention...
August 2010: Magnetic Resonance Imaging Clinics of North America
V E Sinitsyn, N A Chueva
PURPOSE: To define the role of diffusion-weighted imaging and MRI contrast enchanced in the differential diagnostics of focal liver lesions. METHODS AND MATERIALS: Forty patients with focal liver lesions (23 metastases, 32 cysts, 24 hemangiomas) underwent MRI at 1.5 T scanner. The protocol included T1, T2-imaging, DWI. For DWI we used b = 50, 400 s/mm2. Coefficient of signal intensity (kSI) for different sequences was counted by the formula: kSI = (SIa-SIb)/(SIa + SIb), where SIa was the lesion signal intensity, SIb was SI of normal liver parenchyma...
2010: Experimental & Clinical Gastroenterology
W D Holder, R L White, J H Zuger, E J Easton, F L Greene
OBJECTIVE: The purpose of this study was to determine the sensitivity, specificity, and clinical utility of 18F 2-fluoro-2-deoxy-D-glucose (FDG) total-body positron emission tomography (PET) scanning for the detection of metastases in patients with malignant melanoma. SUMMARY BACKGROUND DATA: Recent preliminary reports suggest that PET using FDG may be more sensitive and specific for detection of metastatic melanoma than standard radiologic imaging studies using computed tomography (CT)...
May 1998: Annals of Surgery
L Kreel
There is now a wide choice of medical imaging to show both focal and diffuse pathologies in various organs. Conventional radiology with plain films, fluoroscopy and contrast medium have many advantages, being readily available with low-cost apparatus and a familiarity that almost leads to contempt. The use of plain films in chest disease and in trauma does not need emphasizing, yet there are still too many occasions when the answer obtainable from a plain radiograph has not been available. The film may have been mislaid, or the examination was not requested, or the radiograph had been misinterpreted...
April 1991: Postgraduate Medical Journal
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