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https://www.readbyqxmd.com/read/29778636/surgeon-performed-ultrasound-for-the-assessment-of-parotid-masses
#1
Melissa Zheng, Karolina A Plonowska, Madeleine P Strohl, William R Ryan
BACKGROUND: Studies on parotid gland ultrasound assessments performed specifically by surgeons are seldom reported. METHODS: Retrospective series of a single academic surgeon experience, analyzing 70 new parotid masses with evaluable preoperative SP-US characteristics, location measurements, and perioperative events. RESULTS: 31/70 masses were malignant. SP-US characteristics significantly associated with both malignancy and positive margins included extraparenchymal extension, irregular borders, hypervascularity, infiltration, and the lack of deep enhancement...
April 16, 2018: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/29778285/subcutaneous-tissue-metastasis-from-glioblastoma-multiforme-a-case-report-and-review-of-the-literature
#2
Natalia Frade Porto, Juan Delgado Fernández, María de Los Ángeles García Pallero, Juan Ramón Penanes Cuesta, Paloma Pulido Rivas, Ricardo Gil Simoes
Glioblastoma multiforme is the most common primary brain tumor, despite an aggressive clinical course, less than 2% of patients develop extraneural metastasis. We present a 72-year-old male diagnosed with a right temporal glioblastoma due to headache. He underwent total gross resection surgery and after that the patient was treated with adyuvant therapy. Five months after the patient returned with trigeminal neuralgia, and MRI showed an infratemporal cranial mass which infiltrates masticator space, the surrounding bone, the temporal muscle and superior cervical and parotid lymph nodes...
May 16, 2018: Neurocirugía
https://www.readbyqxmd.com/read/29768362/intraductal-papilloma-arising-from-the-accessory-parotid-gland-a-case-report-and-literature-review
#3
Shuai Sun, Panpan Wang, Yufan Wang, Wen Su, Feng Wang, Hongyu Yang
RATIONALE: Intraductal papillomas of the accessory parotid glands are extremely rare benign tumors that are most commonly derived from minor salivary glands and are easily misdiagnosed as other diseases. Studying these lesions by pathology and immunohistochemistry can raise awareness of the disease, reduce the rate of misdiagnosis, and provide more precise treatments. PATIENT CONCERNS: A 35-year-old man first presented to our hospital with a 6-month history of a painless mass on his left parotid gland...
May 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29745753/does-acoustic-radiation-force-elastography-improve-the-diagnostic-capability-of-ultrasound-in-the-preoperative-characterization-of-masses-of-the-parotid-gland
#4
Pamela Zengel, Florian Notter, Dirk Andre Clevert
OBJECTIVES: Ultrasound is the method of choice for preoperative evaluation of tumors of the parotid glands. However, existing methods do not allow for clear differentiation between the most common benign tumors and malignant tumors. The aim of our study was to evaluate if acoustic radiation force, Virtual Touch Quantification (VTQ) elastography helps to improve the preoperative evaluation of parotid masses. METHODS: We investigated the parenchyma of 102 parotid glands, fourteen lymph nodes of healthy volunteers and 51 tumors of the parotid gland via ultrasound, color Doppler ultrasound and VTQ...
May 10, 2018: Dento Maxillo Facial Radiology
https://www.readbyqxmd.com/read/29728174/sialoblastoma-in-chin-and-management-of-treatment
#5
Qian Wang, Sainan Ma, Huanhuan Chen, Mingli Yang, Weisong Cai
OBJECTIVE: Sialoblastoma is a rare salivary gland tumor mainly located in parotid. In this article, we aimed to review the clinical manifestations and treatments of sialoblastoma, especially to provide effective chemotherapy regimens to instruct internal medicine therapy for unresectable or recurrent tumors. METHOD: We reported a 1-year old girl who presented a left-sided firm facial mass and subsequently diagnosed as sialoblastoma. Afterwards, we reviewed and analyzed relevant literatures...
June 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29725854/metastasising-pleomorphic-salivary-adenoma-a-rare-case-report-of-a-massive-untreated-minor-salivary-gland-pleomorphic-adenoma-with-concurrent-ipsilateral-cervical-node-metastases
#6
Melanie Watson, Peter McAllister, Brendan Conn, Morna MacNeill, Thomas P B Handley
Salivary gland tumours constitute approximately 1-5% of all human neoplasms. Pleomorphic adenoma (PA) is the commonest benign neoplasm affecting the parotid gland most often (> 75%), followed by the submandibular gland (13%), then the palate (9%). Metastasising pleomorphic adenoma (MPA) is extremely rare. The effects can be severe and a reported 40% of MPA patients die with disease. This case represents the first known case in English literature of an untreated minor salivary gland PSA of the palate metastasising to an ipsilateral cervical node...
May 3, 2018: Head and Neck Pathology
https://www.readbyqxmd.com/read/29719559/fine-needle-aspiration-cytology-finding-of-a-parotid-mass-with-chondromyxoid-matrix-and-variable-epithelial-cytological-atypia
#7
https://www.readbyqxmd.com/read/29713928/evaluation-of-parotid-glands-in-healthy-children-and-adolescents-using-shear-wave-elastography-and-superb-microvascular-imaging
#8
Emine Caliskan, Mehmet Ozturk, Zuhal Bayramoglu, Rana Gunoz Comert, Ibrahim Adaletli
OBJECTIVES: We aim to determine parotid gland elasticity values from healthy children and adolescents using shear wave elastography (SWE). We also define the degree of vascularity using superb microvascular imaging (SMI), power Doppler (PD), and color Doppler (CD) and compare SMI with CD and PD. MATERIALS AND METHODS: A total of 100 cases, comprising 50 girls and 50 boys, with ages ranging from 3 to 17 years were included in this prospective study. SWE, SMI, PD, and CD measurements were taken from both parotid glands, and the relationships with sex, age, and body mass index (BMI) were determined...
April 30, 2018: La Radiologia Medica
https://www.readbyqxmd.com/read/29704388/unrecognised-igg4-association-in-progressively-transformed-germinal-centers-of-lymph-nodes-with-subsequent-full-blown-igg4-related-chronic-fibrosing-pancreatitis-a-case-report
#9
H J Son, H Lee, J H Kim, I K Yu, H Y Han
Progressively transformed germinal centers (PTGC) is a benign process characterised by a morphological variant of reactive follicular hyperplasia in lymph nodes. It was recently shown that some cases of PTGC are associated with IgG4-related disease (IgG4-RD) or increased IgG4 plasma cells. Five years ago, a 57-year-old woman presented with enlargement of multiple lymph nodes in the left parotid, submandibular, and neck areas, pathologically diagnosed as PTGC after excisional biopsy. Since then, she has experienced numbness in her extremities, especially the left shoulder and arm, pruritus on the left side of the face and intermittent facial palsy, for which she has been receiving regular symptomatic treatment...
April 2018: Malaysian Journal of Pathology
https://www.readbyqxmd.com/read/29679454/primary-lymphoepthelial-carcinoma-of-the-parotid-gland-pictorial-review-of-a-rare-entity
#10
Arani Halder, Jennifer Sommerville, Mitesh Gandhi
Lymphoepithelial carcinoma (LEC) is a rare malignancy of the salivary gland arising from the parotid in 80% of cases. LEC is indistinguishable histologically from more common non-keratinising undifferentiated nasopharyngeal carcinoma (NPC). Up to 40% of patients with primary LEC present with a cervical metastasis and histological assessment of the primary lesion or nodal metastasis may be reported as NPC. The absence of a nasopharyngeal lesion on imaging and endoscopic assessment together with a parotid mass strengthens the case for a LEC...
April 20, 2018: Journal of Medical Imaging and Radiation Oncology
https://www.readbyqxmd.com/read/29649019/nut-carcinoma-of-the-salivary-glands-clinicopathologic-and-molecular-analysis-of-3-cases-and-a-survey-of-nut-expression-in-salivary-gland-carcinomas
#11
Abbas Agaimy, Isabel Fonseca, Carmo Martins, Khin Thway, Ryan Barrette, Kevin J Harrington, Arndt Hartmann, Christopher A French, Cyril Fisher
NUT carcinoma (NC) represents a rare subset of highly aggressive poorly differentiated carcinomas characterized by rearrangement of the NUT (aka NUTM1, nuclear protein in testis) gene, most commonly fused to BRD4. Originally described as a mediastinal/thymic malignancy, NC has been reported at a variety of anatomic regions including the upper and lower aerodigestive tract. To date, only 7 NC cases of probable salivary gland origin have been reported. We herein describe 3 new cases (all affecting the parotid gland) in 2 women (39- and 55-y old) and 1 man (35-y old)...
April 11, 2018: American Journal of Surgical Pathology
https://www.readbyqxmd.com/read/29609439/a-better-facial-contour-accomplished-by-parotid-duct-preserving-superficial-parotidectomy
#12
Jun Ho Park, Chang Yong Choi, Syeo Young Wee, Young Man Lee
Depression of facial contour after parotidectomy is still challenging to many of surgeons. A 68-year-old man presented with a 4-month history of a painless swelling in both parotid area. The mass was multiple and fixed at the parotid region. We conducted a parotid duct preserving bilateral superficial parotidectomy by one-stage operation to remove the multiple tumors. A lazy S incision was made in both preauricular area and the peripheral branches of the facial nerve were identified using surgical landmark...
March 2018: Archives of Craniofacial Surgery
https://www.readbyqxmd.com/read/29608294/assessment-of-sample-preparation-bias-in-mass-spectrometry-based-proteomics
#13
Frank Klont, Linda Bras, Justina Clarinda Wolters, Sara Ongay, Rainer Bischoff, Gyorgy B Halmos, Péter Horvatovich
For mass spectrometry-based proteomics, the selected sample preparation strategy is a key determinant for information that will be obtained. However, the corresponding selection is often not based on a fit-for-purpose evaluation. Here we report a comparison of in-gel (IGD), in-solution (ISD), on-filter (OFD), and on-pellet digestion (OPD) workflows on the basis of targeted (QconCAT-multiple reaction monitoring (MRM) method for mitochondrial proteins) and discovery proteomics (data dependent acquisition, DDA) analyses using three different human head and neck tissues (i...
April 2, 2018: Analytical Chemistry
https://www.readbyqxmd.com/read/29594083/large-parotid-gland-lipoblastoma-in-a-teenager
#14
Danny Jandali, Ashley Heilingoetter, Ritu Ghai, Jill Jeffe, Samer Al-Khudari
Background: Lipoblastomas are rare benign neoplasms that arise from fetal white fat cells. They are typically found in children under the age of 3 and have been reported in the mediastinum, extremities, and infrequently in the head and neck. We present a rare case of a lipoblastoma arising from the parotid gland and the first known report of a parotid lipoblastoma in a teenager. Case presentation: A 15-year-old male presented with a painless, slowly enlarging parotid mass and left facial swelling...
2018: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/29566949/secretory-carcinoma-of-the-parotid-with-adenoid-cystic-carcinoma-cytological-pattern-a-cytological-pathological-correlation-with-literature-review
#15
Oleksandr Kravtsov, Bryan Hunt, Jess Peterson, Luis Carrillo, Peter Bonneau, Tamara Giorgadze
Secretory carcinoma (SC) is a rare low-grade malignant tumor, defined by ETV6-NTRK3 fusion, identifiable by FISH. We describe a case in a 58-year-old male with a painless slowly growing 16mm palpable mass within left superficial parotid. FNA of the mass showed highly cellular specimen with moderate to large pleomorphic cells with round to ovoid nuclei with vesicular chromatin and distinct nucleoli. Cells had moderate to large amounts of vacuolated cytoplasm. Abundant globular metachromatic material, resembling that of adenoid cystic carcinoma, was noted...
April 2018: Annals of Diagnostic Pathology
https://www.readbyqxmd.com/read/29552253/successful-sclerotherapy-of-a-recurrent-benign-parotid-cyst
#16
William Wong, Mohammed F Loya, Alexander Martynov, Salman S Shah, Dean Berman
Benign parotid lesions can grow to be a cosmetic deformation with psychological sequelae for a patient. Although surgical resection is the treatment of choice, cyst aspiration has also been attempted. This, however, has been shown to recur, requiring repeat intervention. An alternative therapeutic method not as widely recognized, but which has been reported to be both effective and less invasive than surgery for treating parotid cyst lesions, is sclerotherapy. Here we describe a report of a patient with a benign, localized, cystic neck mass refractory to 2 trials of fine needle aspiration...
February 2018: Radiology Case Reports
https://www.readbyqxmd.com/read/29549132/a-huge-pleomorphic-adenoma-of-the-submandibular-salivary-gland
#17
Ashutosh Rai, Sushil Sharma, Prabhat Shrivastava, Mangal Singh
The most common tumour of salivary gland is pleomorphic adenoma (PA). They are benign, painless, can grow into big tumours but usually do not affect nerves or lymph nodes. PA most commonly occurs in the parotid gland but it may involve submandibular, lingual and minor salivary glands also. They can attain giant proportions and weigh several kilograms. We report a giant PA arising in the submandibular gland and treated by complete surgical excision without any complication. A female patient presented with a tumour in the submandibular region and front of neck with a history of more than 18 years...
March 16, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29493727/syncope-caused-by-a-pleomorphic-adenoma-case-report-and-literature-review
#18
Anas Minkara, Reena Dhanda-Patil, Yash Patil
Pleomorphic adenomas are considered the most common salivary gland tumors, although they rarely occur in the parapharyngeal space. To the best of our knowledge, this is the first case report of a parapharyngeal parotid pleomorphic adenoma causing syncope. A 57-year-old man was admitted for left-sided blurred vision, left-sided weakness, dysarthria, lightheadedness, and syncope. Upon his admission, an electrocardiogram showed sinus bradycardia, and computed tomography of the neck with contrast showed a large parapharyngeal mass involving the prestyloid compartment, leading to compression of blood flow through the internal carotid artery...
January 2018: Ear, Nose, & Throat Journal
https://www.readbyqxmd.com/read/29493724/buccal-space-malignancy-in-the-setting-of-chronic-sialadenitis-a-report-of-2-cases
#19
Lucas M Bryant, Patrick Tassone, Joseph Curry, Adam Luginbuhl, David Cognetti
We report the cases of an 89-year-old woman and a 77-year-old woman with long-standing chronic sialadenitis (60 and 10 years, respectively) who were referred to our large academic medical center for sialendoscopy. Both patients presented with symptoms of acute parotid duct obstruction in the background of long-standing parotid duct disease. Imaging demonstrated ductal dilation and periductal inflammation and, along with the clinical findings, was supportive of a diagnosis of acute parotitis in the setting of chronic obstructive parotid disease...
January 2018: Ear, Nose, & Throat Journal
https://www.readbyqxmd.com/read/29484010/mucoepidermoid-carcinoma-mec-of-parotid-gland-with-massive-cutaneous-involvement-bilateral-pedicle-advancement-flap-u-plasty-as-adequate-surgical-approach
#20
Ilia Lozev, Sonya Ruseva, Ivan Pidakev, José Carlos Cardoso, Uwe Wollina, Torello Lotti, Georgi Konstantinov Maximov, Ivan Terziev, Georgi Tchernev
Neoplasms of the major and minor salivary glands are morphologically and a clinically diverse group of neoplasms which lead the clinician to diagnostic and management challenges. This article aims to report a case of mucoepidermoid carcinoma in 83 - year - old woman who presented in the dermatology clinic with a tumour mass in the left auricular area. The patient complained of pain and abnormal bleeding of the mass. The lesion was examined, and surgical treatment was performed. A tumour was extirpated, and partial resection of both the parotid gland and the sternocleidomastoid muscle was done...
January 25, 2018: Open Access Macedonian Journal of Medical Sciences
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