keyword
MENU ▼
Read by QxMD icon Read
search

OCD spectrum

keyword
https://www.readbyqxmd.com/read/28407363/de-novo-unbalanced-translocation-4p-duplication-8p-deletion-in-a-patient-with-autism-ocd-and-overgrowth-syndrome
#1
Angela Sagar, Dalila Pinto, Fedra Najjar, Stephen J Guter, Carol Macmillan, Edwin H Cook
Chromosomal abnormalities, such as unbalanced translocations and copy number variants (CNVs), are found in autism spectrum disorders (ASDs) [Sanders et al. () Neuron 70: 863-885]. Many chromosomal abnormalities, including sub microscopic genomic deletions and duplications, are missed by G-banded karyotyping or Fragile X screening alone and are picked up by chromosomal microarrays [Shen et al. () Pediatrics 125: e727-735]. Translocations involving chromosomes 4 and 8 are possibly the second most frequent translocation in humans and are often undetected in routine cytogenetics [Giglio et al...
April 13, 2017: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/28389841/an-initial-case-series-of-intensive-cognitive-behavioral-therapy-for-obsessive-compulsive-disorder-in-adolescents-with-autism-spectrum-disorder
#2
Marina Iniesta-Sepúlveda, Joshua M Nadeau, Amaya Ramos, Brian Kay, Bradley C Riemann, Eric A Storch
Obsessive-compulsive disorder (OCD) is prevalent among youth with autism spectrum disorder (ASD). Cognitive-behavioral therapy (CBT) with ASD-specific modifications has support for treating OCD in this population; however, use of intensive CBT in youth with ASD and severe OCD has not been tested. The current study examined the preliminary effectiveness of an individualized intensive CBT protocol for OCD in adolescents with ASD. Nine adolescents (aged 11-17 years) completed a regimen of intensive CBT (range 24-80 daily sessions) incorporating exposure with response prevention (ERP)...
April 7, 2017: Child Psychiatry and Human Development
https://www.readbyqxmd.com/read/28374658/the-inner-world-of-overactive-monitoring-neural-markers-of-interoception-in-obsessive-compulsive-disorder
#3
A Yoris, A M García, L Traiber, H Santamaría-García, M Martorell, F Alifano, R Kichic, J S Moser, M Cetkovich, F Manes, A Ibáñez, L Sedeño
BACKGROUND: Obsessive-compulsive disorder (OCD) patients typically overmonitor their own behavior, as shown by symptoms of excessive doubt and checking. Although this is well established for the patients' relationship with external stimuli in the environment, no study has explored their monitoring of internal body signals, a process known to be affected in anxiety-related syndromes. Here, we explored this issue through a cardiac interoception task that measures sensing of heartbeats. Our aim was to explore key behavioral and electrophysiological aspects of internal-cue monitoring in OCD, while examining their potential distinctiveness in this condition...
April 4, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28300008/prevalence-of-suicide-attempt-and-clinical-characteristics-of-suicide-attempters-with-obsessive-compulsive-disorder-a-report-from-the-international-college-of-obsessive-compulsive-spectrum-disorders-icocs
#4
Bernardo Dell'Osso, Beatrice Benatti, Chiara Arici, Carlotta Palazzo, A Carlo Altamura, Eric Hollander, Naomi Fineberg, Dan J Stein, Humberto Nicolini, Nuria Lanzagorta, Donatella Marazziti, Stefano Pallanti, Michael van Ameringen, Christine Lochner, Oguz Karamustafalioglu, Luchezar Hranov, Martijn Figee, Lynne Drummond, Carolyn I Rodriguez, John Grant, Damiaan Denys, Jose M Menchon, Joseph Zohar
OBJECTIVE: Obsessive-compulsive disorder (OCD) is associated with variable risk of suicide and prevalence of suicide attempt (SA). The present study aimed to assess the prevalence of SA and associated sociodemographic and clinical features in a large international sample of OCD patients. METHODS: A total of 425 OCD outpatients, recruited through the International College of Obsessive-Compulsive Spectrum Disorders (ICOCS) network, were assessed and categorized in groups with or without a history of SA, and their sociodemographic and clinical features compared through Pearson's chi-squared and t tests...
March 16, 2017: CNS Spectrums
https://www.readbyqxmd.com/read/28281020/restricted-repetitive-behaviors-in-autism-spectrum-disorder-and-obsessive-compulsive-disorder-a-comparative-review
#5
Marina Jiujias, Elizabeth Kelley, Layla Hall
This review paper critically examines literature regarding restricted and repetitive behaviors (RRBs) in Autism Spectrum Disorder (ASD) and Obsessive-Compulsive Disorder (OCD). The similar behavioral profiles of these disorders presents the potential for confusion regarding diagnoses and intervention efforts. As such, this review highlights the similarities and differences between RRBs in ASD and OCD. The developmental trajectories of RRBs are presented, followed by an exploration of three constructs implicated in RRB manifestation: anxiety, executive functioning, and sensory phenomena...
March 9, 2017: Child Psychiatry and Human Development
https://www.readbyqxmd.com/read/28262175/a-qualititative-study-of-neurological-soft-signs-in-obsessive-compulsive-disorder-and-effect-of-comorbid-psychotic-spectrum-disorders-and-familiality-on-its-expression-in-indian-population
#6
Dr Sonia Malhotra, Dr Pankaj B Borade, Dr Pradeep Sharma, Dr Yogesh Satija, Dr Gunjan
INTRODUCTION: Obsessive Compulsive Disorder (OCD) is one of the most common psychiatric disorders, with lifetime prevalence of 2%-3% and is known to lie on a spectrum continuous with Schizophrenia and other affective psychosis. Neurological Soft Signs (NSS) have been reported to be higher in both Schizophrenia and affective psychosis, like bipolar disorder, and their first degree relatives but in OCD, the results have been inconsistent. It remains unclear if NSS occur at even higher rates in individuals who have a co-morbidity for OCD and either schizophrenia or bipolar disorder, as it might be expected if a broader neurodevelopmental hit underlies the pathophysiology of both OCD and these disorders...
February 2017: Asian Journal of Psychiatry
https://www.readbyqxmd.com/read/28154539/temporal-association-of-certain-neuropsychiatric-disorders-following-vaccination-of-children-and-adolescents-a-pilot-case-control-study
#7
Douglas L Leslie, Robert A Kobre, Brian J Richmand, Selin Aktan Guloksuz, James F Leckman
BACKGROUND: Although the association of the measles, mumps, and rubella vaccine with autism spectrum disorder has been convincingly disproven, the onset of certain brain-related autoimmune and inflammatory disorders has been found to be temporally associated with the antecedent administration of various vaccines. This study examines whether antecedent vaccinations are associated with increased incidence of obsessive-compulsive disorder (OCD), anorexia nervosa (AN), anxiety disorder, chronic tic disorder, attention deficit hyperactivity disorder, major depressive disorder, and bipolar disorder in a national sample of privately insured children...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/28032202/pediatric-obsessive-compulsive-disorder-with-tic-symptoms-clinical-presentation-and-treatment-outcome
#8
Davíð R M A Højgaard, Gudmundur Skarphedinsson, Judith Becker Nissen, Katja A Hybel, Tord Ivarsson, Per Hove Thomsen
Some studies have shown that children and adolescents with obsessive-compulsive disorder (OCD) and co-morbid tics differ from those without co-morbid tics in terms of several demographic and clinical characteristics. However, not all studies have confirmed these differences. This study examined children and adolescents with OCD and with possible or definite tic specifiers according to the DSM-5 in order to see whether they differ from patients without any tic symptoms regarding clinical presentation and outcome of cognitive behavioral therapy (CBT)...
December 28, 2016: European Child & Adolescent Psychiatry
https://www.readbyqxmd.com/read/27887721/comparative-multimodal-meta-analysis-of-structural-and-functional-brain-abnormalities-in-autism-spectrum-disorder-and-obsessive-compulsive-disorder
#9
Christina O Carlisi, Luke J Norman, Steve S Lukito, Joaquim Radua, David Mataix-Cols, Katya Rubia
BACKGROUND: Autism spectrum disorder (ASD) and obsessive-compulsive disorder (OCD) share inhibitory control deficits possibly underlying poor control over stereotyped and repetitive and compulsive behaviors, respectively. However, it is unclear whether these symptom profiles are mediated by common or distinct neural profiles. This comparative multimodal meta-analysis assessed shared and disorder-specific neuroanatomy and neurofunction of inhibitory functions. METHODS: A comparative meta-analysis of 62 voxel-based morphometry and 26 functional magnetic resonance imaging (fMRI) studies of inhibitory control was conducted comparing gray matter volume and activation abnormalities between patients with ASD (structural MRI: 911; fMRI: 188) and OCD (structural MRI: 928; fMRI: 247) and control subjects...
October 13, 2016: Biological Psychiatry
https://www.readbyqxmd.com/read/27869250/preliminary-analyses-of-psychometric-characteristics-of-the-polish-version-of-the-obsessive-compulsive-inventory-revised-oci-r-in-a-non-clinical-sample
#10
Justyna Mojsa-Kaja, Krystyna Golonka, Magda Gawłowska
OBJECTIVES: Obsessive-compulsive disorder (OCD) is an anxiety-spectrum disorder that affects 1-2% of the adult population. People with OCD are more likely to report impaired social and occupational functioning. Although effective treatments of the OCD exist, many sufferers from this disorder are continuously misdiagnosed. Therefore, improving the assessment of the OCD remains an important area of scientific research. The main goal of the study is the initial verification of psychometric properties in the Polish version of the Obsessive-Compulsive Inventory-Revised (OCI-R) in a college student sample...
November 18, 2016: International Journal of Occupational Medicine and Environmental Health
https://www.readbyqxmd.com/read/27869141/fronto-striatal-glutamate-in-autism-spectrum-disorder-and-obsessive-compulsive-disorder
#11
Jilly Naaijen, Marcel P Zwiers, Houshang Amiri, Steven C R Williams, Sarah Durston, Bob Oranje, Daniel Brandeis, Regina Boecker-Schlier, Matthias Ruf, Isabella Wolf, Tobias Banaschewski, Jeffrey C Glennon, Barbara Franke, Jan K Buitelaar, David J Lythgoe
Autism spectrum disorders (ASDs) and obsessive compulsive disorder (OCD) are often comorbid with the overlap based on compulsive behaviors. Although previous studies suggest glutamatergic deficits in fronto-striatal brain areas in both disorders, this is the first study to directly compare the glutamate concentrations across the two disorders with those in healthy control participants using both categorical and dimensional approaches. In the current multi-center study (four centers), we used proton magnetic resonance spectroscopy in 51 children with ASD, 29 with OCD, and 53 healthy controls (aged 8-13 years) to investigate glutamate (Glu) concentrations in two regions of the fronto-striatal circuit: midline anterior cingulate cortex (ACC) and left dorsal striatum...
December 14, 2016: Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/27862704/what-happens-to-children-who-move-off-the-autism-spectrum-clinical-follow-up-study
#12
Nahit Motavalli Mukaddes, Tuba Mutluer, Basak Ayik, Ayla Umut
BACKGROUND: There is controversial information on outcome of school age individuals who lose the diagnosis of autism and achieve "optimal outcome" (OO). The present study assessed the autism symptoms and other psychiatric disorders in a group of children with a past history of autism. METHODS: The subjects consisted of 26 individuals who had lost the diagnosis of autism 2-8 years previously. Clinical assessment was done with both parents and children. Diagnostic and Statistical Manual of Mental Disorders (5th edn; DSM-V) criteria were used for diagnosis of autism spectrum disorder (ASD)...
November 12, 2016: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/27834163/is-not-just-right-experience-njre-in-obsessive-compulsive-disorder-part-of-an-autistic-phenotype
#13
Josselyn Hellriegel, Caroline Barber, Maheshi Wikramanayake, Naomi A Fineberg, William Mandy
OBJECTIVE: Harm avoidance (HA) and "not just right experience" (NJRE) have been proposed to be 2 core motivational processes underlying obsessive-compulsive disorder (OCD). The objective of this study was to explore whether NJRE demarcates a neurodevelopmental OCD subgroup distinct from HA related to autistic traits and/or to a broader phenotype of cognitive rigidity and sensory processing difficulties associated with an earlier age of OCD onset. METHODS: A correlational design investigated whether NJRE and HA are distinct entities in OCD and explored their relationship to autism spectrum disorder (ASD) traits measured by the Autism Quotient (AQ), sensory processing, set-shifting, and age of OCD onset in an OCD sample (N=25)...
November 11, 2016: CNS Spectrums
https://www.readbyqxmd.com/read/27782808/compuls-design-of-a-multicenter-phenotypic-cognitive-genetic-and-magnetic-resonance-imaging-study-in-children-with-compulsive-syndromes
#14
Jilly Naaijen, Saskia de Ruiter, Marcel P Zwiers, Jeffrey C Glennon, Sarah Durston, David J Lythgoe, Steven C R Williams, Tobias Banaschewski, Daniel Brandeis, Barbara Franke, Jan K Buitelaar
BACKGROUND: Compulsivity, the closely linked trait impulsivity and addictive behaviour are associated with several neurodevelopmental disorders, including attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder (ASD), and obsessive compulsive disorder (OCD). All three disorders show impaired fronto-striatal functioning, which may be related to altered glutamatergic signalling. Genetic factors are also thought to play an important role in the aetiology of compulsivity-related disorders...
October 26, 2016: BMC Psychiatry
https://www.readbyqxmd.com/read/27730476/relationship-between-symptom-dimensions-and-brain-morphology-in-obsessive-compulsive-disorder
#15
Motohisa Hirose, Yoshiyuki Hirano, Kiyotaka Nemoto, Chihiro Sutoh, Kenichi Asano, Haruko Miyata, Junko Matsumoto, Michiko Nakazato, Koji Matsumoto, Yoshitada Masuda, Masaomi Iyo, Eiji Shimizu, Akiko Nakagawa
Obsessive-compulsive disorder (OCD) is known as a clinically heterogeneous disorder characterized by symptom dimensions. Although substantial numbers of neuroimaging studies have demonstrated the presence of brain abnormalities in OCD, their results are controversial. The clinical heterogeneity of OCD could be one of the reasons for this. It has been hypothesized that certain brain regions contributed to the respective obsessive-compulsive dimensions. In this study, we investigated the relationship between symptom dimensions of OCD and brain morphology using voxel-based morphometry to discover the specific regions showing alterations in the respective dimensions of obsessive-compulsive symptoms...
October 11, 2016: Brain Imaging and Behavior
https://www.readbyqxmd.com/read/27716920/modified-cognitive-behavior-therapy-for-severe-treatment-resistant-obsessive-compulsive-disorder-in-an-adolescent-with-autism-spectrum-disorder
#16
Georgina Krebs, Kim Murray, Amita Jassi
There is a high rate of comorbidity between obsessive-compulsive disorder (OCD) and autism spectrum disorders (ASD). Standard cognitive-behavior therapy (CBT) protocols have been shown to be less effective in treating OCD in young people with ASD than in typically developing youth. This case study describes the treatment of an adolescent boy with severe, treatment-resistant OCD and ASD using a modified CBT approach. Modifications to a standard evidence-based CBT for OCD protocol included extended psychoeducation about anxiety; regular home-based sessions; and increased involvement of systems, including family and school...
November 2016: Journal of Clinical Psychology
https://www.readbyqxmd.com/read/27669819/schizo-obsessive-spectrum-disorders-an-update
#17
Estêvão Scotti-Muzzi, Osvaldo Luis Saide
The presence of obsessive-compulsive symptoms (OCS) and obsessive-compulsive disorders (OCD) in schizophrenia is frequent, and a new clinical entity has been proposed for those who show the dual diagnosis: the schizo-obsessive disorder. This review scrutinizes the literature across the main academic databases, and provides an update on different aspects of schizo-obsessive spectrum disorders, which include schizophrenia, schizotypal personality disorder (SPD) with OCD, OCD with poor insight, schizophrenia with OCS, and schizophrenia with OCD (schizo-obsessive disorder)...
September 27, 2016: CNS Spectrums
https://www.readbyqxmd.com/read/27656365/arthroscopic-microfracture-for-osteochondritis-dissecans-lesions-of-the-capitellum
#18
Christopher L Camp, Joshua S Dines, Ryan M Degen, Alec L Sinatro, David W Altchek
Capitellar osteochondritis dissecans (OCD) is one of the most common causes of elbow pain and dysfunction in adolescent athletes. It typically occurs in gymnasts and overhead throwers and presents along a wide spectrum of severity. Stable lesions can typically be treated with conservative therapy; however, those presenting with instability, fragmentation, or loose bodies generally require surgical intervention. Although there are a number of described surgical options used to treat capitellar OCD lesions, microfracture is one of the most commonly performed and well studied...
June 2016: Arthroscopy Techniques
https://www.readbyqxmd.com/read/27612598/diagnosis-and-treatment-of-obsessive-compulsive-behavior-in-a-boy-with-duchenne-muscular-dystrophy-and-autism-spectrum-disorder-a-case-report
#19
Jos G M Hendriksen, Sylvia Klinkenberg, Phillipe Collin, Brenda Wong, Erik H Niks, Johan S Vles
We describe a case study of comorbid obsessive-compulsive disorder (OCD) in a nine-year-old boy with Duchenne muscular dystrophy (DMD). Patient history included persistent deficits in social communication and restrictive and repetitive patterns of behavior: a diagnosis of autism spectrum was formalized. Due to serious disruption on social functioning and negative development of the obsessive behavior we decided to start pharmacotherapy. Fluoxetine 5 mg/day was started and gradually increased to 20 mg/day...
October 2016: Neuromuscular Disorders: NMD
https://www.readbyqxmd.com/read/27518760/occupational-contact-sensitization-in-female-geriatric-nurses-data-of-the-information-network-of-departments-of-dermatology-ivdk-2005-2014
#20
S Schubert, A Bauer, S Molin, C Skudlik, J Geier
BACKGROUND: Geriatric nurses (GN) have a high risk of occupational contact dermatitis (OCD), with chronic irritant contact dermatitis predominating. However, allergic contact dermatitis is an important issue as well. Little is known whether the relevant occupational allergen spectrum reported in the 1990s, including fragrances, preservatives, rubber chemicals and ingredients of surface disinfectants to be the most common sensitizers in GN, is still valid. OBJECTIVES: To monitor the current allergen spectrum in GN with OCD and verify the validity of the patch test recommendations (baseline-, preservative-, ointment base-, rubber-, disinfectant, series and fragrances) in GN with suspected OCD given by the German Contact Dermatitis Research Group (DKG)...
March 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
keyword
keyword
119682
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"