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https://www.readbyqxmd.com/read/28413664/extranodal-natural-killer-t-cell-lymphoma-presenting-as-cavernous-sinus-syndrome
#1
Hong-Cheng Mai, Dan-Xia Chen, Dan Lu, Yu-Sheng Zhang
Extranodal natural killer (NK)/T-cell lymphomas are rare, highly aggressive tumors of the central nervous system (CNS) that commonly affect the nasal cavity or paranasal sinuses. NK/T-cell lymphomas are associated with a poor prognosis, as they exhibit a wide range of unique clinical presentations and neuroimaging findings that are currently difficult to detect. Pathological examination is considered to be more reliable for defining the pathological entity of NK/T-cell lymphoma. Early testing for fluorodeoxyglucose (FDG)-positron emission tomography combined with computed tomography may improve the evaluation of lymphomas, which have been known to display avid (18)FDG uptake...
April 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/28407432/diagnosis-of-biofilm-infections-in-cystic-fibrosis-patients
#2
REVIEW
Niels Høiby, Thomas Bjarnsholt, Claus Moser, Peter Østrup Jensen, Mette Kolpen, Tavs Qvist, Kasper Aanaes, Tanja Pressler, Marianne Skov, Oana Ciofu
Chronic Pseudomonas aeruginosa biofilm lung infection in cystic fibrosis patients is the best described biofilm infection in medicine. The initial focus can be the paranasal sinuses and then follows repeated colonization and infection of the lungs by aspiration. The matrix of the biofilms is dominated by alginate and the pathogenesis of tissue damage is immune complex-mediated chronic inflammation dominated by polymorphonuclear leukocytes and their products (DNA, oxygen radicals and proteases). The P. aeruginosa biofilm infection can be diagnosed by microscopy of lung tissue, sputum and mucus from the paranasal sinuses, where aggregates of the bacteria are found surrounded by the abundant alginate matrix...
April 2017: APMIS: Acta Pathologica, Microbiologica, et Immunologica Scandinavica
https://www.readbyqxmd.com/read/28405168/the-black-evil-affecting-patients-with-diabetes-a-case-of-rhino-orbito-cerebral-mucormycosis-causing-garcin-syndrome
#3
Santhosh Narayanan, Geetha Panarkandy, Gomathy Subramaniam, Chandni Radhakrishnan, N K Thulaseedharan, Neeraj Manikath, Sreejith Ramaswamy, Suma Radhakrishnan, Danish Ekkalayil
Mucormycosis is a life-threatening infection affecting patients with diabetes. It is an angioinvasive disease often resistant to treatment with a debilitating course and high mortality. Here, we report a case of a 45 year old woman with type 2 diabetes mellitus who presented to us with history of right-sided ptosis and facial palsy, and subsequently developed loss of vision and palatal palsy. She was in diabetic ketoacidosis. Nervous system examination revealed involvement of right second, third, fourth, sixth, seventh, ninth, and tenth cranial nerves, suggestive of Garcin syndrome...
2017: Infection and Drug Resistance
https://www.readbyqxmd.com/read/28403108/analyses-and-treatments-of-postoperative-nasal-complications-after-endonasal-transsphenoidal-resection-of-pituitary-neoplasms
#4
You Cheng, Fei Xue, Tian-You Wang, Jun-Feng Ji, Wei Chen, Zhi-Yi Wang, Li Xu, Chun-Hua Hang, Xin-Feng Liu
In this study, we analyze and discuss the treatments of postoperative nasal complications after endonasal transsphenoidal resection of pituitary neoplasms (PNs). We performed 129 endonasal transsphenoidal resections of PNs and analyzed and treated cases with nasal complications. After endonasal transsphenoidal resection of PNs, there were 26 cases of postoperative nasal complications (20.1%), including nasal hemorrhage (4.8%), cerebrospinal fluid rhinorrhea (6.9%), sphenoid sinusitis (2.3%), atrophic rhinitis (1...
April 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28400825/association-of-anatomic-variations-with-antrochoanal-polyps-in-paranasal-sinus-computed-tomography-scan
#5
Ali Hekmatnia, Farid Shirvani, Farhad Mahmoodi, Mostafa Hashemi
BACKGROUND: This study was designed to determine the prevalence of concomitant anatomic variation of paranasal sinuses in patients with antrochoanal polyp (ACP). MATERIALS AND METHODS: Among patients referred by their clinicians for standard computed tomography scan of paranasal sinuses septal deviation, concha bullosa, and retention cyst were evaluated in both patients with ACP as well as in a control group. RESULTS: Of the 17 patients with ACP, fifteen patients (88...
2017: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://www.readbyqxmd.com/read/28398769/potential-involvement-of-the-epidermal-growth-factor-receptor-ligand-epiregulin-and-matrix-metalloproteinase-1-in-pathogenesis-of-chronic-rhinosinusitis
#6
Tetsuya Homma, Atsushi Kato, Masafumi Sakashita, Tetsuji Takabayashi, James E Norton, Lydia A Suh, Roderick G Carter, Kathleen E Harris, Anju T Peters, Leslie C Grammer, Jin-Young Min, Stephanie Shintani-Smith, Bruce K Tan, Kevin Welch, David B Conley, Robert C Kern, Robert P Schleimer
RATIONALE: Chronic rhinosinusitis (CRS) is a heterogeneous chronic inflammatory disease of the nose and paranasal sinuses that presents without (CRSsNP) or with nasal polyps (CRSwNP). Features of CRSwNP are the frequent presence of type 2 allergic inflammation and high prevalence of Staphylococcus aureus (SA) colonization. As inflammation persists, sinus tissue undergoes epithelial damage and repair along with polyp growth. Since one feature of damaged tissue is enhancement of growth factor signaling, we evaluated the presence of EGFR ligands and MMPs in CRS...
April 11, 2017: American Journal of Respiratory Cell and Molecular Biology
https://www.readbyqxmd.com/read/28397561/a-case-report-and-systematic-review-of-eosinophilic-angiocentric-fibrosis-of-the-paranasal-sinuses
#7
REVIEW
Molly E Heft Neal, Nicholas R Rowan, Thomas J Willson, Eric W Wang, Stella E Lee
OBJECTIVE: There is a paucity of literature discussing prognostic factors or comparing outcomes in eosinophilic angiocentric fibrosis (EAF). This review aims to analyze tumor and patient characteristics as possible prognostic markers and compare surgical approaches. METHODS: Systematic literature review and case report analyzing available cases of EAF located within the paranasal sinuses. RESULTS: The literature search yielded 39 articles meeting criteria for a total of 59 cases (including 1 from our institution)...
May 2017: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/28395407/-the-clinical-characteristics-of-17-cases-of-primary-ciliary-dyskinesia
#8
X L Tian, S B Wang, S Y Zheng, X Li, K F Xu
Objective: To review the clinical data of cases of primary ciliary dyskinesia (PCD), and to explore the clinical characteristics for the understanding of PCD. Methods: We retrospectively summarized 17 patients with PCD diagnosed in Peking Union Medical College Hospital from Jan 2009 to Dec 2014. There were 7 male and 10 female patients, with the age from 6 to 57 years at the time of diagnosis. The mean onset age of the disease was 11.7±2.1 years, and the mean age at diagnosis was 29.5±3.5 years. We analyzed their clinical symtoms, radiologic images, pulmonary function test and the electron microscopic findings for the clinical characteristics of PCD...
April 12, 2017: Chinese Journal of Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/28389992/detection-of-biofilms-in-biopsies-from-chronic-rhinosinusitis-patients-in-vitro-biofilm-forming-ability-and-antimicrobial-susceptibility-testing-in-biofilm-mode-of-growth-of-isolated-bacteria
#9
Mariagrazia Di Luca, Elena Navari, Semih Esin, Melissa Menichini, Simona Barnini, Andrej Trampuz, Augusto Casani, Giovanna Batoni
Chronic rhinosinusitis (CRS) is the most common illness among chronic disorders that remains poorly understood from a pathogenic standpoint and has a significant impact on patient quality of life, as well as healthcare costs. Despite being widespread, little is known about the etiology of the CRS. Recent evidence, showing the presence of biofilms within the paranasal sinuses, suggests a role for biofilm in the pathogenesis. To elucidate the role of biofilm in the pathogenesis of CRS, we assessed the presence of biofilm at the infection site and the ability of the aerobic flora isolated from CRS patients to form biofilm in vitro...
April 8, 2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/28389018/topical-drug-therapies-for-chronic-rhinosinusitis
#10
REVIEW
Lauren J Luk, John M DelGaudio
Chronic rhinosinusitis is recognized as an inflammatory syndrome involving the nose and paranasal sinuses of multifactorial etiology. Research has demonstrated a complex interplay between host factors, microbiota, environmental exposures, and epigenetics resulting in chronic mucosal inflammation. The mainstay of medical therapy addresses this inflammation. In previously operated sinuses this includes topical saline and corticosteroids, reserving antibiotics for culture-directed acute exacerbations. Topical antiinflammatory therapies allow increased local concentration of drugs while minimizing side effects...
April 4, 2017: Otolaryngologic Clinics of North America
https://www.readbyqxmd.com/read/28384896/significance-of-blood-eosinophil-count-in-patients-with-chronic-rhinosinusitis-with-nasal-polyposis
#11
Ammu Sreeparvathi, Lathi Kumari Kalyanikuttyamma, Madhumita Kumar, Nandagopan Sreekumar, Narendrakumar Veerasigamani
INTRODUCTION: Chronic Rhino Sinusitis (CRS) is one of the most prevalent chronic illnesses across the globe, affecting persons of all ages. It is an inflammatory process that involves the paranasal sinuses with symptoms lasting longer than 12 weeks. AIM: To establish the significance of blood eosinophil (count) levels in CRS with nasal polyps and to compare blood eosinophil count with eosinophil count in the histopathology specimens of the polyps. MATERIALS AND METHODS: This was a retrospective study done to review the medical records of 63 patients who underwent endoscopic sinus surgery for CRS with Nasal polyps...
February 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28377544/anthropometry-of-arabian-nose-using-computed-tomography-scanning
#12
Sami Alharethy, Ibrahim Al-Quniabut, Yong Ju Jang
BACKGROUND: The nose plays a critical role in determining the external appearance of an individual. We studied the craniofacial anthropometrics by CT scanning since previous studies in the field were conducted in Saudi populations using photometric analysis. OBJECTIVES: Obtain objective and quantitative data that can help surgeons plan cosmetic procedures for the nose. DESIGN: A cross-sectional analytical study. SETTING: Department of Otorhinolaryngology, Head and Neck Surgery, King Abdulaziz University Hospital, King Saud University, Riyadh, Saudi Arabia from February 2015 to December 2015...
March 2017: Annals of Saudi Medicine
https://www.readbyqxmd.com/read/28374239/radiological-imaging-findings-of-dyke-davidoff-masson-syndrome
#13
Erkan Gökçe, Murat Beyhan, Recep Sade
Radiological findings of Dyke-Davidoff-Masson syndrome (DDMS) in patients with different etiologies are presented in our study. The study included 12 patients (seven females, five males) for whom radiological examinations were requested due to reasons such as epilepsy, mental retardation, and/or hemiplegia. CT was performed in 12, MRI in 6, MRA in 1, and DSA in 1 patient. Following imaging findings were evaluated: cerebral and cerebellar involvement (laterality, encephalomalacia), affected territories, ventricular enlargement, sulcal enlargement, calvarial thickening, and paranasal sinus enlargement hyperaeration...
April 3, 2017: Acta Neurologica Belgica
https://www.readbyqxmd.com/read/28373883/cephalometric-analysis-for-gender-determination-using-maxillary-sinus-index-a-novel-dimension-in-personal-identification
#14
Tanya Khaitan, Arpita Kabiraj, Uday Ginjupally, Ritika Jain
Purpose. Radiography is important in forensic odontology for the identification of humans. The maxillary sinus is the largest of the paranasal sinuses and first to develop. Sinus radiography has been used for identification of skeletal remains and determination of gender. Hence, the aim and objectives of the present study were to establish a new method for gender determination using maxillary sinus index from lateral cephalometric radiographs and to establish the reliability of maxillary sinus for gender determination...
2017: International Journal of Dentistry
https://www.readbyqxmd.com/read/28357086/a-large-psammomatoid-ossifying-fibroma-with-proptosis-a-case-report
#15
Zhi-Yuan Zhang, Mei-Ping Min, Yang Liu, Hong-Qun Jiang, Jian Zhang
The psammomatoid ossifying fibroma (POF) is a rare and benign fibro-osseous lesion predominantly affecting the paranasal sinuses and orbits of children and young adults. The diagnosis and management of the lesion remains challenging. The present study reported a rare case of a large POF in a 39-year-old male patient. The patient had a 30 year history of a slowly growing tumor and this had resulted in right craniofacial deformity, as well as right lateral displacement of the eye ball. Due to the large tumor size, surgical removal of the lesion was the predominant treatment...
February 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/28352486/unilateral-maxillary-sinus-actinomycosis-with-a-closed-oroantral-fistula
#16
Jason E Cohn, Mark Lentner, Hui Li, Matthew Nagorsky
Actinomycosis is a bacterial infection due to Actinomyces israelii, a gram-positive, anaerobic organism that normally affects the cervicofacial region. However, facial injury or trauma (i.e., dental procedures) can allow this bacteria to inhabit other regions. There have been rare reports of actinomycosis of the paranasal sinuses. We present a case of a 50-year-old female who originally presented with a suspected oroantral fistula who subsequently was found to have actinomycosis involving her right maxillary sinus...
2017: Case Reports in Otolaryngology
https://www.readbyqxmd.com/read/28351395/follicular-thyroid-carcinoma-metastasis-to-the-facial-skeleton-a-systematic-review
#17
Varun V Varadarajan, Elizabeth K Pace, Vatsal Patel, Raja Sawhney, Robert J Amdur, Peter T Dziegielewski
BACKGROUND: Follicular thyroid carcinoma (FTC) metastasis to the facial skeleton is exceedingly rare. A case of FTC metastasizing to the mandible is presented and a systematic review of the literature describing thyroid metastasis to the facial skeleton is performed. CASE PRESENTATION: A 73-year-old female presented with metastatic FTC to the mandible and underwent total thyroidectomy, segmental mandibulectomy, bone impacted fibular free flap reconstruction, and adjuvant radioactive iodine treatment...
March 28, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28348652/nasal-septal-deviation-and-concha-bullosa-do-they-have-an-impact-on-maxillary-sinus-volumes-and-prevalence-of-maxillary-sinusitis
#18
Iwona Kucybała, Konrad Adam Janik, Szymon Ciuk, Dawid Storman, Andrzej Urbanik
BACKGROUND: The aim of the study was to assess if the presence of nasal septal deviation and concha bullosa is connected with the development of sinuses and the incidence of inflammation within them. MATERIAL/METHODS: We retrospectively analysed 214 patients who underwent paranasal sinus computed tomography. There were 125 females and 89 males, the mean age being 47.67±16.74 years (range 18-97). Exclusion criteria included: age under 18 years, prior sinonasal surgery and S-shaped septum...
2017: Polish Journal of Radiology
https://www.readbyqxmd.com/read/28341352/volumetric-analysis-of-the-maxillary-sphenoid-and-frontal-sinuses-a-comparative-computerized-tomography-based-study
#19
Oded Cohen, Meir Warman, Moran Fried, Hagit Shoffel-Havakuk, Meital Adi, Doron Halperin, Yonatan Lahav
OBJECTIVE: To study volume characteristics of the maxillary, sphenoid and frontal sinuses among healthy Caucasians adults, using computed tomography (CT) scans. METHODS: A retrospective, case series study in a single academic center, CT scans of 201 consecutive adult subjects, performed between January and September 2014, were reviewed for the volume and dimensions of the paranasal sinuses. Patients with documented sinus pathology or lack of pneumatization were excluded...
March 21, 2017: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/28339134/paranasal-sinus-lymphoma-retrospective-review-with-focus-on-clinical-features-histopathology-prognosis-and-relationship-to-systemic-lymphoma
#20
Brynn N Wajda, Mindy R Rabinowitz, Gurston G Nyquist, Stacey K Mardekian, Marc R Rosen, Michael P Rabinowitz
BACKGROUND: Paranasal sinus lymphoma is a rare clinical entity. METHODS: We conducted a retrospective case series of 68 patients with biopsy-confirmed paranasal sinus lymphoma with attention on systemic disease association. RESULTS: Of 63 patients with paranasal sinus lymphoma, 35 (56%) had systemic involvement. Four patient groups were identified: (1) primary paranasal sinus lymphoma (44%); (2) systemic disease occurring concurrently with paranasal sinus lymphoma (25%); (3) paranasal sinus lymphoma with relapse of preexisting systemic lymphoma (22%); and (4) progression to systemic disease after primary paranasal sinus lymphoma (8%)...
March 24, 2017: Head & Neck
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