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https://www.readbyqxmd.com/read/28631771/-dying-in-the-three-graces-arms-when-ethics-dresses-up-as-aesthetics
#1
Sandro Spinsanti
The many adjectives usually used to explain the desirable death - painless, decent, human… - do not include the term "graceful". However, this is a way that can be explored, too, if you imagine to die in the Three Graces' arms, namely in a mood that, according to Ugo Foscolo, is "between the exaggerated cheerfulness and the deep pain". The pathway turns out to be much more productive if we allow ourselves to be led by the original names of the Three Graces and by their symbology. Euphrosyne suggests the wisdom through which the mind guides our choices, especially those that show as palliative cures; Aglaea suggests the peace linked to the possibility to keep the death process under control; Talia lets us imagine a death seen as growth, as a pathway that ends at the peak of our own humanity...
June 2017: Recenti Progressi in Medicina
https://www.readbyqxmd.com/read/28602382/value-in-oral-and-maxillofacial-surgery-a-systematic-review-of-economic-analyses
#2
Benjamin Geisler, Yisi D Ji, Zachary S Peacock
PURPOSE: The purpose of this study is to describe the state of economic analyses in the field of oral and maxillofacial surgery (OMS). MATERIALS AND METHODS: A systematic search of published literature up to 2016 was performed. The inclusion criteria were as follows: English-language articles on economic analyses pertaining to OMS including anesthesia and pain management; dentoalveolar surgery; orthognathic, cleft, and/or obstructive sleep apnea treatment; pathology; reconstruction; temporomandibular disorders; trauma; and other...
May 18, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28580762/static-beam-tomotherapy-as-an-optimisation-method-in-whole-breast-radiation-therapy-wbrt
#3
Matthew Squires, Yunfei Hu, Mikel Byrne, Ben Archibald-Heeren, Sonja Cheers, Bruno Bosco, Amy Teh, Andrew Fong
INTRODUCTION: TomoTherapy (Accuray, Sunnyvale, CA) has recently introduced a static form of tomotherapy: TomoDirect™ (TD). This study aimed to evaluate TD against a contemporary intensity modulated radiation therapy (IMRT) alternative through comparison of target and organ at risk (OAR) doses in breast cancer cases. A secondary objective was to evaluate planning efficiency by measuring optimisation times. METHODS: Treatment plans of 27 whole-breast radiation therapy (WBRT) patients optimised with a tangential hybrid IMRT technique were replanned using TD...
June 4, 2017: Journal of Medical Radiation Sciences
https://www.readbyqxmd.com/read/28578712/pharmacoeconomic-studies-in-world-health-organization-eastern-mediterranean-countries-reporting-completeness
#4
Qais Alefan, Karen Rascati
OBJECTIVES: The aim of this study was to evaluate the extent of reporting necessary information in published health economic research in World Health Organization Eastern Mediterranean Countries (WHO EMC). METHODS: A systematic literature search was conducted using PubMed and Google Scholar to identify pharmacoeconomic studies conducted in WHO EMC. The inclusion criteria for the studies were: (i) original studies, (ii) compared pharmaceutical services or drugs, (iii) conducted in WHO EMC, (iv) manuscript published in English...
June 5, 2017: International Journal of Technology Assessment in Health Care
https://www.readbyqxmd.com/read/28541078/ensembles-in-medial-and-lateral-orbitofrontal-cortex-construct-cognitive-maps-emphasizing-different-features-of-the-behavioral-landscape
#5
Nina Lopatina, Brian F Sadacca, Michael A McDannald, Clay V Styer, Jacob F Peterson, Joseph F Cheer, Geoffrey Schoenbaum
The orbitofrontal cortex (OFC) has long been implicated in the ability to use the current value of expected outcomes to guide behavior. More recently, this specific role has been conceptualized as a special case of a more general function that OFC plays in constructing a "cognitive map" of the behavioral task space by labeling the current task state and learning relationships among task states. Here, we have used single unit recording data from 2 prior studies to examine whether and how information relating different states within and across trials is represented in medial versus lateral OFC in rats...
June 2017: Behavioral Neuroscience
https://www.readbyqxmd.com/read/28535792/caught-between-a-rock-and-a-hard-place-mental-health-of-migrant-live-in-caregivers-in-canada
#6
Mandana Vahabi, Josephine Pui-Hing Wong
BACKGROUND: Canada depends on Temporary Foreign Workers (TFWs), also known as migrant workers, to fill labour shortage in agriculture, hospitality, construction, child/senior care, and other low-skilled occupations. Evidence shows that TFWs, especially women live-in caregivers (LC), constitute a vulnerable population. Their health is compromised by the precarious and harsh working and living conditions they encounter. There is a paucity of research on the mental health of LCs, their support systems and access to mental health services...
May 23, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28532067/development-of-biocompatible-and-safe-polyethersulfone-hemodialysis-membrane-incorporated-with-functionalized-multi-walled-carbon-nanotubes
#7
Muhammad Nidzhom Zainol Abidin, Pei Sean Goh, Ahmad Fauzi Ismail, Mohd Hafiz Dzarfan Othman, Hasrinah Hasbullah, Noresah Said, Siti Hamimah Sheikh Abdul Kadir, Fatmawati Kamal, Mohd Sohaimi Abdullah, Be Cheer Ng
A novel approach in the design of a safe, high performance hemodialysis membrane is of great demand. Despite many advantages, the employment of prodigious nanomaterials in hemodialysis membrane is often restricted by their potential threat to health. Hence, this work focusses on designing a biocompatible polyethersulfone (PES) hemodialysis membrane embedded with poly (citric acid)-grafted-multi walled carbon nanotubes (PCA-g-MWCNTs). Two important elements which could assure the safety of the nanocomposite membrane, i...
August 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28516822/key-drivers-of-patient-experience-in-ambulatory-paediatric-cardiology
#8
Shalini D Allam, Mary Mehta, Bertha Ben Khallouq, James F Burrows, Paul Rosen
Patient experience is becoming a central focus of healthcare. A broad range of studies on how to increase patient satisfaction ratings exists; however, they lack the specificity to adequately guide physicians and hospitals on how to improve patient experience. The objective of this study was to define the aspects of patient experience within paediatric cardiologist practices that can serve as predictors of excellent patient satisfaction. From 1 January, 2013 to 28 February, 2015 (26 months), outpatients who visited paediatric cardiologists were asked to complete a 39-question patient satisfaction survey regarding their experience...
May 18, 2017: Cardiology in the Young
https://www.readbyqxmd.com/read/28514308/emotional-exhaustion-induced-latent-autoimmune-diabetes-in-adults-in-a-young-lady-a-care-compliant-case-report
#9
Yin-Ling Chen, Yong-Chao Qiao, Xin-Nan Song, Wei Ling, Hai-Lu Zhao, Xiao-Xi Zhang
RATIONALE: Latent autoimmune diabetes in adults (LADA) refers to an autoimmune disorder characterized with detectable islets antibodies in the early diagnosis and increased autoimmune beta-cell failure progression. Notably, this kind of diabetes seems to be confused with other phenotypic diabetes. PATIENT CONCERNS: A young woman suffered an emotional exhaustion-induced LADA, showing asthenia, polydipsia, polyuria, and visible weight loss. The patient emotionally ended a 14-year romantic relationship, leading to the emotional flooding...
May 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28492110/characteristics-of-influential-peers-in-the-eyes-of-secondary-school-students-a-mixed-method-study
#10
Alice Y Loke, Yim-Wah Mak, Cynthia S T Wu
Aim It is the aim of this study to explore the characteristics of influential peers identified by schoolmates, and the mechanism by which they exert their influence on their peers. BACKGROUND: Adolescent crowds are a salient influence on the health-risk behaviors of peers, contributing to adolescent substance use such as drinking alcohol, smoking cigarettes, and taking drugs. METHODS: A mixed method study. Three schools granted us access to students and those who had been nominated as influential by their peers...
May 11, 2017: Primary Health Care Research & Development
https://www.readbyqxmd.com/read/28486142/the-age-related-expression-decline-of-ercc1-and-xpf-for-forensic-age-estimation-a-preliminary-study
#11
Xiao-Dong Deng, Qin Gao, Wei Zhang, Bo Zhang, Ying Ma, Li-Xia Zhang, Cheer Muer, Ying Xie, Yun Liu
The age-related capacity decline of DNA damage repair in human peripheral blood has been demonstrated. Excision repair cross-complementation group1 (ERCC1) and Xeroderma pigmentosum complementation group F (XPF) were rate-limiting enzyme in nucleotide excision repair (NER) which was known as the most important DNA damage repair system. Consequently, we hypothesized that the expression and/or activity of ERCC1 and XPF may be associated with age. However, little was known about the quantitative relationship of ERCC1 and XPF expression levels with age...
July 2017: Journal of Forensic and Legal Medicine
https://www.readbyqxmd.com/read/28484409/studying-irony-detection-beyond-ironic-criticism-let-s-include-ironic-praise
#12
Richard Bruntsch, Willibald Ruch
Studies of irony detection have commonly used ironic criticisms (i.e., mock positive evaluation of negative circumstances) as stimulus materials. Another basic type of verbal irony, ironic praise (i.e., mock negative evaluation of positive circumstances) is largely absent from studies on individuals' aptitude to detect verbal irony. However, it can be argued that ironic praise needs to be considered in order to investigate the detection of irony in the variety of its facets. To explore whether the detection ironic praise has a benefit beyond ironic criticism, three studies were conducted...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28476628/cost-effectiveness-analysis-of-vaccinations-and-decision-makings-on-vaccination-programmes-in-hong-kong-a-systematic-review
#13
REVIEW
Carlos K H Wong, Qiuyan Liao, Vivian Y W Guo, Yiqiao Xin, Cindy L K Lam
OBJECTIVES: To describe and systematically review the modelling and reporting of cost-effectiveness analysis of vaccination in Hong Kong, and to identify areas for quality enhancement in future cost-effectiveness analyses. METHODS: We conducted a comprehensive and systematic review of cost-effectiveness studies related to vaccination and government immunisation programmes in Hong Kong published from 1990 to 2015, through database search of Pubmed, Web of Science, Embase, and OVID Medline...
May 31, 2017: Vaccine
https://www.readbyqxmd.com/read/28476121/menopausal-hormone-therapy-a-systematic-review-of-cost-effectiveness-evaluations
#14
Louiza S Velentzis, Usha Salagame, Karen Canfell
BACKGROUND: Several evaluations of the cost-effectiveness (CE) of menopausal hormone therapy (MHT) have been reported. The aim of this study was to systematically and critically review economic evaluations of MHT since 2002, after the Women's Health Initiative (WHI) trial results on MHT were published. METHODS: The inclusion criteria for the review were: CE analyses of MHT versus no treatment, published from 2002-2016, in healthy women, which included both symptom relief outcomes and a range of longer term health outcomes (breast cancer, coronary heart disease, stroke, fractures and colorectal cancer)...
May 5, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28450060/endocannabinoid-modulation-of-dopamine-neurotransmission
#15
REVIEW
Dan Covey, Yolanda Mateo, David Sulzer, Joseph F Cheer, David M Lovinger
Dopamine (DA) is a major catecholamine neurotransmitter in the mammalian brain that controls neural circuits involved in the cognitive, emotional, and motor aspects of goal-directed behavior. Accordingly, perturbations in DA neurotransmission play a central role in several neuropsychiatric disorders. Somewhat surprisingly given its prominent role in numerous behaviors, DA is released by a relatively small number of densely packed neurons originating in the midbrain. The dopaminergic midbrain innervates numerous brain regions where extracellular DA release and receptor binding promote short- and long-term changes in postsynaptic neuron function...
April 24, 2017: Neuropharmacology
https://www.readbyqxmd.com/read/28434588/the-endocannabinoid-system-as-a-target-for-novel-anxiolytic-drugs
#16
REVIEW
Sachin Patel, Mathew N Hill, Joseph F Cheer, Carsten T Wotjak, Andrew Holmes
The endocannabinoid (eCB) system has attracted attention for its role in various behavioral and brain functions, and as a therapeutic target in neuropsychiatric disease states, including anxiety disorders and other conditions resulting from dysfunctional responses to stress. In this mini-review, we highlight components of the eCB system that offer potential 'druggable' targets for new anxiolytic medications, emphasizing some of the less well-discussed options. We discuss how selectively amplifying eCBs recruitment by interfering with eCB-degradation, via fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL), has been linked to reductions in anxiety-like behaviors in rodents and variation in human anxiety symptoms...
May 2017: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/28364972/association-of-atopy-phenotypes-with-new-development-of-asthma-and-bronchial-hyperresponsiveness-in-school-aged-children
#17
Eun Lee, Si Hyeon Lee, Young-Ho Kim, Hyun-Ju Cho, Jisun Yoon, Song-I Yang, Young-Ho Jung, Hyung Young Kim, Ju-Hee Seo, Ji-Won Kwon, Hyo-Bin Kim, So Yeon Lee, Ho-Jang Kwon, Soo-Jong Hong
BACKGROUND: Although previous studies have investigated the association between atopy phenotypes and allergic diseases, atopy characterizations in association with the development of allergic diseases remain poorly understood. OBJECTIVE: To identify atopy phenotypes in school-age children and to evaluate the association between atopy phenotypes and allergic diseases. METHODS: We enrolled 616 children with atopy defined as 1 or more positive allergen responses on skin prick tests and 665 children without atopy from the Children's Health and Environmental Research (CHEER) study...
May 2017: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/28355231/a-systematic-review-of-economic-evaluations-of-population-based-sodium-reduction-interventions
#18
Silvia F Hope, Jacqui Webster, Kathy Trieu, Arti Pillay, Merina Ieremia, Colin Bell, Wendy Snowdon, Bruce Neal, Marj Moodie
OBJECTIVE: To summarise evidence describing the cost-effectiveness of population-based interventions targeting sodium reduction. METHODS: A systematic search of published and grey literature databases and websites was conducted using specified key words. Characteristics of identified economic evaluations were recorded, and included studies were appraised for reporting quality using the Consolidated Health Economic Evaluation Reporting Standards (CHEERS) checklist...
2017: PloS One
https://www.readbyqxmd.com/read/28290257/an-analysis-of-partial-efficiencies-of-energy-utilisation-of-different-macronutrients-by-barramundi-lates-calcarifer-shows-that-starch-restricts-protein-utilisation-in-carnivorous-fish
#19
Brett D Glencross, David Blyth, Nicholas Bourne, Susan Cheers, Simon Irvin, Nicholas M Wade
This study examined the effect of including different dietary proportions of starch, protein and lipid, in diets balanced for digestible energy, on the utilisation efficiencies of dietary energy by barramundi (Lates calcarifer). Each diet was fed at one of three ration levels (satiety, 80 % of initial satiety and 60 % of initial satiety) for a 42-d period. Fish performance measures (weight gain, feed intake and feed conversion ratio) were all affected by dietary energy source. The efficiency of energy utilisation was significantly reduced in fish fed the starch diet relative to the other diets, but there were no significant effects between the other macronutrients...
February 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28290105/economic-evaluations-of-thrombophilia-screening-prior-to-prescribing-combined-oral-contraceptives-a-systematic-and-critical-review
#20
REVIEW
Erin Vernon, Bridget Hiedemann, Bonnie H Bowie
BACKGROUND: Combined oral contraceptives (COCs) increase the risk of venous thromboembolism (VTE), particularly among women with inherited clotting disorders. The World Health Organization classifies combined hormonal contraception as an "unacceptable health risk" for women with thrombogenic mutations but advises against universal thrombophilia screening before prescribing COCs given the low prevalence of thrombophilia and high screening costs. OBJECTIVE: Through the lens of lifetime costs and benefits, this paper systematically and critically reviews all published economic evaluations of thrombophilia screening prior to prescribing COCs...
March 13, 2017: Applied Health Economics and Health Policy
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