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https://www.readbyqxmd.com/read/28290257/an-analysis-of-partial-efficiencies-of-energy-utilisation-of-different-macronutrients-by-barramundi-lates-calcarifer-shows-that-starch-restricts-protein-utilisation-in-carnivorous-fish
#1
Brett D Glencross, David Blyth, Nicholas Bourne, Susan Cheers, Simon Irvin, Nicholas M Wade
This study examined the effect of including different dietary proportions of starch, protein and lipid, in diets balanced for digestible energy, on the utilisation efficiencies of dietary energy by barramundi (Lates calcarifer). Each diet was fed at one of three ration levels (satiety, 80 % of initial satiety and 60 % of initial satiety) for a 42-d period. Fish performance measures (weight gain, feed intake and feed conversion ratio) were all affected by dietary energy source. The efficiency of energy utilisation was significantly reduced in fish fed the starch diet relative to the other diets, but there were no significant effects between the other macronutrients...
March 14, 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28290105/economic-evaluations-of-thrombophilia-screening-prior-to-prescribing-combined-oral-contraceptives-a-systematic-and-critical-review
#2
REVIEW
Erin Vernon, Bridget Hiedemann, Bonnie H Bowie
BACKGROUND: Combined oral contraceptives (COCs) increase the risk of venous thromboembolism (VTE), particularly among women with inherited clotting disorders. The World Health Organization classifies combined hormonal contraception as an "unacceptable health risk" for women with thrombogenic mutations but advises against universal thrombophilia screening before prescribing COCs given the low prevalence of thrombophilia and high screening costs. OBJECTIVE: Through the lens of lifetime costs and benefits, this paper systematically and critically reviews all published economic evaluations of thrombophilia screening prior to prescribing COCs...
March 13, 2017: Applied Health Economics and Health Policy
https://www.readbyqxmd.com/read/28283378/the-effects-of-synthetic-cannabinoid-ur-144-on-the-human-body-a-review-of-39-cases
#3
Piotr Adamowicz, Joanna Gieroń, Dominika Gil, Wojciech Lechowicz, Agnieszka Skulska, Bogdan Tokarczyk
UR-144 [(1-pentyl-1H-indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)methanone] is a synthetic cannabinoid, which has been detected in many 'legal highs', seized from the global drug market since the beginning of 2012. It has gained popularity as a 'legal' alternative to classic cannabis in countries where it was not controlled. Despite the widespread distribution of this substance, the data on its effects on the human body are scarce. Therefore, this paper describes the results of analysis and observed effects in 39 cases in which UR-144 was determined in blood...
March 7, 2017: Forensic Science International
https://www.readbyqxmd.com/read/28271341/mantras-help-the-general-psychological-well-being-of-college-students-a-pilot-study
#4
Aruna Lolla
The mind receives deep effect of harmonizing from incantatory spiritual verse known as "mantra." This ancient Indian spiritual science of sound vibrations had been used to help the mind, body and life. Students in top-ranking colleges often feel pressurized and complain of depression. Mantras could help ease their stress. This work attempts to study the impact of mantra on the psychological well-being of college students. Volunteers selected and listened to the mantra of their choice in the test period. Psychological tests were conducted before and after the test period...
March 7, 2017: Journal of Religion and Health
https://www.readbyqxmd.com/read/28260345/-health-economic-evaluation-reporting-guideline-and-application-status
#5
J Xiao, J F Sun, Q Q Wang, X Qi, H Y Yao
Using the guidelines of health economic evaluation reporting is conducive to regulating the contents of this reporting, improving the quality of studies into health economics evaluation. This article summarized the history of the guidelines and specified the instrument used to study " Quality of Health Economic Studies (QHES)" and the checklist about Consolidated Health Economics Evaluation Reporting Standards (CHEERS)-the two specific evaluation contents in this guideline, the article also introduced its present application status of the guideline and its pros and cons...
March 6, 2017: Zhonghua Yu Fang Yi Xue za Zhi [Chinese Journal of Preventive Medicine]
https://www.readbyqxmd.com/read/28203120/international-lessons-in-new-methods-for-grading-and-integrating-cost-effectiveness-evidence-into-clinical-practice-guidelines
#6
REVIEW
Kathryn M Antioch, Michael F Drummond, Louis W Niessen, Hindrik Vondeling
Economic evidence is influential in health technology assessment world-wide. Clinical Practice Guidelines (CPG) can enable economists to include economic information on health care provision. Application of economic evidence in CPGs, and its integration into clinical practice and national decision making is hampered by objections from professions, paucity of economic evidence or lack of policy commitment. The use of state-of-art economic methodologies will improve this. Economic evidence can be graded by 'checklists' to establish the best evidence for decision making given methodological rigor...
2017: Cost Effectiveness and Resource Allocation: C/E
https://www.readbyqxmd.com/read/28195023/cheer-national-study-of-chronic-rhinosinusitis-practice-patterns
#7
Nikita Chapurin, Melissa A Pynnonen, Rhonda Roberts, Kristine Schulz, Jennifer J Shin, David L Witsell, Kourosh Parham, Alan Langman, David Carpenter, Andrea Vambutas, Anh Nguyen-Huynh, Anne Wolfley, Walter T Lee
Objectives (1) Describe national patterns of chronic rhinosinusitis (CRS) care across academic and community practices. (2) Determine the prevalence of comorbid disorders in CRS patients, including nasal polyposis, allergic rhinitis, asthma, and cystic fibrosis. (3) Identify demographic, clinical, and practice type factors associated with endoscopic sinus surgery (ESS). Study Design Multisite cross-sectional study. Setting Otolaryngology's national research network CHEER (Creating Healthcare Excellence through Education and Research)...
February 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28186690/reduced-levels-of-cacna1c-attenuate-mesolimbic-dopamine-system-function
#8
Chantelle E Terrillion, David T Dao, Roger Cachope, Mary Kay Lobo, Adam C Puche, Joseph F Cheer, Todd D Gould
Genetic variation in CACNA1C, which codes for the L-type calcium channel (LTCC) Cav 1.2, is associated with clinical diagnoses of bipolar disorder, depression, and schizophrenia. Dysregulation of the mesolimbic dopamine (DA) system is linked to these syndromes and LTCCs are required for normal DAergic neurotransmission between the ventral tegmental area (VTA) and nucleus accumbens (NAc). It is unclear, however, how variations in CACNA1C genotype, and potential subsequent changes in expression levels in these regions, modify risk...
February 10, 2017: Genes, Brain, and Behavior
https://www.readbyqxmd.com/read/28152012/what-is-the-economic-evidence-for-mhealth-a-systematic-review-of-economic-evaluations-of-mhealth-solutions
#9
Sarah J Iribarren, Kenrick Cato, Louise Falzon, Patricia W Stone
BACKGROUND: Mobile health (mHealth) is often reputed to be cost-effective or cost-saving. Despite optimism, the strength of the evidence supporting this assertion has been limited. In this systematic review the body of evidence related to economic evaluations of mHealth interventions is assessed and summarized. METHODS: Seven electronic bibliographic databases, grey literature, and relevant references were searched. Eligibility criteria included original articles, comparison of costs and consequences of interventions (one categorized as a primary mHealth intervention or mHealth intervention as a component of other interventions), health and economic outcomes and published in English...
2017: PloS One
https://www.readbyqxmd.com/read/28150850/chewing-versus-swallowing-ticagrelor-to-accelerate-platelet-inhibitionin-acute-coronary-syndrome-the-cheers-study-for-the-platis-platelets-and-thrombosis-in-sheba-study-group
#10
Elad Asher, Shir Frydman, Moshe Katz, Ehud Regev, Avi Sabbag, Israel Mazin, Arsalan Abu-Much, Andrew Kukuy, Anna Mazo, Aharon Erez, Anat Berkovitch, Michael Narodistky, Israel Barbash, Amit Segev, Roy Beigel, Shlomi Matetzky
It was the study objective to evaluate whether chewing a 180 mg loading dose of ticagrelor versus an equal dose of traditional oral administration, enhances inhibition of platelet aggregation 1 hour (h) after administering a ticagrelor loading dose in non-ST elevation myocardial infarction (NSTEMI) patients. Dual anti-platelet therapy represents standard care for treating NSTEMI patients. Ticagrelor is a direct acting P2Y12 inhibitor and, unlike clopidogrel and prasugrel, does not require metabolic activation...
February 2, 2017: Thrombosis and Haemostasis
https://www.readbyqxmd.com/read/28139085/improving-the-methods-for-the-economic-evaluation-of-medical-devices
#11
Rosanna Tarricone, Giuditta Callea, Marko Ogorevc, Valentina Prevolnik Rupel
Medical devices (MDs) have distinctive features, such as incremental innovation, dynamic pricing, the learning curve and organisational impact, that need to be considered when they are evaluated. This paper investigates how MDs have been assessed in practice, in order to identify methodological gaps that need to be addressed to improve the decision-making process for their adoption. We used the Consolidated Health Economic Evaluation Reporting Standards (CHEERS) checklist supplemented by some additional categories to assess the quality of reporting and consideration of the distinctive features of MDs...
February 2017: Health Economics
https://www.readbyqxmd.com/read/28129026/a-systematic-review-of-health-economic-evaluations-of-vaccines-in-brazil
#12
Ana Marli Christovam Sartori, Luciana Martins Rozman, Tassia Cristina Decimoni, Roseli Leandro, Hillegonda Maria Dutilh Novaes, Patrícia Coelho de Soárez
BACKGROUND: In Brazil, since 2005, the Ministry of Health requires Health Economic Evaluation (HEE) of vaccines for introduction into the National Immunization Program. OBJECTIVES: To describe and analyze the full HEE on vaccines conducted in Brazil from 1980 to 2013. METHODS: Systematic review of the literature. We searched multiple databases. Two researchers independently selected the studies and extracted the data. The methodological quality of individual studies was evaluated using CHEERS items...
January 27, 2017: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/28125365/cost-effectiveness-of-pembrolizumab-versus-ipilimumab-in-ipilimumab-na%C3%A3-ve-patients-with-advanced-melanoma-in-the-united-states
#13
Jingshu Wang, Bartosz Chmielowski, James Pellissier, Ruifeng Xu, Kendall Stevinson, Frank Xiaoqing Liu
BACKGROUND: Recent clinical trials have shown that pembrolizumab significantly prolonged progression-free survival and overall survival compared with ipilimumab in ipilimumab-naïve patients with unresectable or metastatic melanoma. However, there has been no published evidence on the cost-effectiveness of pembrolizumab for this indication. OBJECTIVE: To assess the long-term cost-effectiveness of pembrolizumab versus ipilimumab in ipilimumab-naïve patients with unresectable or meta-static melanoma from a U...
February 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28121042/economic-case-for-intraoperative-interventions-to-prevent-surgical-site-infection
#14
REVIEW
B M Gillespie, W Chaboyer, A Erichsen-Andersson, R M Hettiarachchi, S Kularatna
BACKGROUND: Surgical-site infection (SSI) occurs in 1-10 per cent of all patients undergoing surgery; rates can be higher depending on the type of surgery. The aim of this review was to establish whether (or not) surgical hand asepsis, intraoperative skin antisepsis and selected surgical dressings are cost-effective in SSI prevention, and to examine the quality of reporting. METHODS: The authors searched MEDLINE via Ovid, CINAHL via EBSCO, Cochrane Central and Scopus databases systematically from 1990 to 2016...
January 2017: British Journal of Surgery
https://www.readbyqxmd.com/read/28115340/two-cheers-for-theresa-may-s-discovery-of-child-and-adolescent-mental-health
#15
EDITORIAL
John R Ashton
No abstract text is available yet for this article.
January 23, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28111847/making-economic-evaluations-more-helpful-for-treatment-choices-in-haemophilia
#16
REVIEW
M Drummond, N Houwing, U Slothuus, P Giangrande
AIM: Poorly conducted economic evaluations have the potential to mislead both clinicians, leading to inappropriate treatment choices, and payers who must decide on the reimbursement of treatment costs. This paper reviews the methods used in economic evaluations in haemophilia and proposes standards for conducting and reporting such evaluations in the future. METHODS: A systematic review of economic evaluations in haemophilia published since 2008 was conducted. The reporting and methods of the studies were assessed using the recently published Consolidated Health Economic Evaluation Reporting Guidelines (CHEERS) checklist...
January 22, 2017: Haemophilia: the Official Journal of the World Federation of Hemophilia
https://www.readbyqxmd.com/read/28100000/interdisciplinary-management-of-an-adult-patient-with-significant-restorative-treatment-needs-and-a-complex-malocclusion
#17
Naresh Shah, Desmond Cheer-Vern Ong, Elissa Freer
Transverse maxillary deficiency may be associated with dental crowding, compromised aesthetics and impaired function. Non-surgical correction of maxillary transverse deficiency through rapid maxillary expansion is routinely performed for young patients, however, surgical intervention is generally required for adults. An interdisciplinary treatment approach is necessary to achieve the desired treatment objectives for challenging cases. This case report demonstrates a pleasing treatment outcome for a patient with a severe maxillary transverse deficiency, significant crowding and extensive active caries...
January 18, 2017: Australian Dental Journal
https://www.readbyqxmd.com/read/28098939/a-systematic-review-of-economic-evaluations-of-treatments-for-patients-with-epilepsy
#18
REVIEW
Ben F M Wijnen, Ghislaine A P G van Mastrigt, Silvia M A A Evers, Olga Gershuni, Danielle A J E Lambrechts, Marian H J M Majoie, Debby Postulart, Bert A P Aldenkamp, Reina J A de Kinderen
The increasing number of treatment options and the high costs associated with epilepsy have fostered the development of economic evaluations in epilepsy. It is important to examine the availability and quality of these economic evaluations and to identify potential research gaps. As well as looking at both pharmacologic (antiepileptic drugs [AEDs]) and nonpharmacologic (e.g., epilepsy surgery, ketogenic diet, vagus nerve stimulation) therapies, this review examines the methodologic quality of the full economic evaluations included...
January 18, 2017: Epilepsia
https://www.readbyqxmd.com/read/28086936/association-between-low-blood-lead-levels-and-increased-risk-of-dental-caries-in-children-a-cross-sectional-study
#19
Young-Suk Kim, Mina Ha, Ho-Jang Kwon, Hae-Young Kim, Youn-Hee Choi
BACKGROUND: The objective of this study was to examine the association between low blood lead levels of <5 μg/dL and the development of dental caries among children. METHODS: The Children's Health and Environment Research (CHEER) group recruited a cohort of 7,059 school-aged children from six Korean cities. The final study populations in the permanent and deciduous teeth groups were 1,564 and 1,241 children, respectively, after excluding 4 children with blood lead levels of >5 μg/dL...
January 13, 2017: BMC Oral Health
https://www.readbyqxmd.com/read/28000366/hemocompatibility-evaluation-of-poly-1-8-octanediol-citrate-blend-polyethersulfone-membranes
#20
Muhamad Zulhilmi Zailani, Ahmad Fauzi Ismail, Siti Hamimah Sheikh Abdul Kadir, Mohd Hafiz Dzarfan Othman, Pei Sean Goh, Hasrinah Hasbullah, Mohd Sohaimi Abdullah, Be Cheer Ng, Fatmawati Kamal
In this study, poly (1,8-octanediol citrate) (POC) was used to modify polyethersulfone (PES)-based membrane to enhance its hemocompatibility. Different compositions of POC (0-3%) were added into the polyethersulfone (PES) dope solutions and polyvinylpyrrolidone (PVP) was used as pore forming agent. The hemocompatible POC modified PES membranes were fabricated through phase-inversion technique. The prepared membranes were characterized using attenuated total reflectance-Fourier transform infrared (ATR-FTIR), thermogravimetric analysis (TGA), scanning electron microscopy (SEM), Atomic-force microscopy (AFM), contact angle, Zeta-potential, membrane porosity and pore size and pure water flux (PWF) and BSA rejection...
December 21, 2016: Journal of Biomedical Materials Research. Part A
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