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https://www.readbyqxmd.com/read/29260508/a-systematic-review-of-the-cost-effectiveness-of-biologics-for-ulcerative-colitis
#1
REVIEW
Ewa Stawowczyk, Paweł Kawalec
BACKGROUND: Ulcerative colitis (UC) is a chronic autoimmune inflammation of the colon. The condition significantly decreases quality of life and generates a substantial economic burden for healthcare payers, patients and the society in which they live. Some patients require chronic pharmacotherapy, and access to novel biologic drugs might be crucial for long-term remission. The analyses of cost-effectiveness for biologic drugs are necessary to assess their efficiency and provide the best available drugs to patients...
December 19, 2017: PharmacoEconomics
https://www.readbyqxmd.com/read/29244029/fluorescence-goes-from-strength-to-strength-in-maf
#2
David J S Birch
This year we have been greatly cheered by the near 10% rise in impact factor to 2.7, and the inclusion of Methods and Applications in Fluorescence (MAF) by MEDLINE which means that now all articles can be found on PubMed®.
December 15, 2017: Methods and Applications in Fluorescence
https://www.readbyqxmd.com/read/29241286/-humor-in-medicine-the-art-of-leaping-over-the-shadows
#3
Barbara Wild
Humor and laughter are integral parts of human life and communication - and so of course they occur in medical contacts.Humor is defined as a personality based cognitive emotional style of processing situations, characterized by the ability to find positive aspects even in negative situations, and the ability to communicate this point of view to others and to cheer them up. Humor can support healing processes and coping with illness. Humor and jokes reduce anxiety and stress (for patients and doctors). Humorous people have a more realistic, flexible and less fearful behaviour...
December 2017: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/29216450/endocannabinoid-actions-on-cortical-terminals-orchestrate-local-modulation-of-dopamine-release-in-the-nucleus-accumbens
#4
Yolanda Mateo, Kari A Johnson, Dan P Covey, Brady K Atwood, Hui-Ling Wang, Shiliang Zhang, Iness Gildish, Roger Cachope, Luigi Bellocchio, Manuel Guzmán, Marisela Morales, Joseph F Cheer, David M Lovinger
Dopamine (DA) transmission mediates numerous aspects of behavior. Although DA release is strongly linked to firing of DA neurons, recent developments indicate the importance of presynaptic modulation at striatal dopaminergic terminals. The endocannabinoid (eCB) system regulates DA release and is a canonical gatekeeper of goal-directed behavior. Here we report that extracellular DA increases induced by selective optogenetic activation of cholinergic neurons in the nucleus accumbens (NAc) are inhibited by CB1 agonists and eCBs...
December 6, 2017: Neuron
https://www.readbyqxmd.com/read/29180976/are-clowns-good-for-everyone-the-influence-of-trait-cheerfulness-on-emotional-reactions-to-a-hospital-clown-intervention
#5
Sarah Auerbach
Trait cheerfulness predicts individual differences in experiences and behavioral responses in various humor experiments and settings. The present study is the first to investigate whether trait cheerfulness also influences the impact of a hospital clown intervention on the emotional state of patients. Forty-two adults received a clown visit in a rehabilitation center and rated their emotional state and trait cheerfulness afterward. Facial expressions of patients during the clown visit were coded with the Facial Action Coding System...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/29163289/network-approach-to-understanding-emotion-dynamics-in-relation-to-childhood-trauma-and-genetic-liability-to-psychopathology-replication-of-a-prospective-experience-sampling-analysis
#6
Laila Hasmi, Marjan Drukker, Sinan Guloksuz, Claudia Menne-Lothmann, Jeroen Decoster, Ruud van Winkel, Dina Collip, Philippe Delespaul, Marc De Hert, Catherine Derom, Evert Thiery, Nele Jacobs, Bart P F Rutten, Marieke Wichers, Jim van Os
Background: The network analysis of intensive time series data collected using the Experience Sampling Method (ESM) may provide vital information in gaining insight into the link between emotion regulation and vulnerability to psychopathology. The aim of this study was to apply the network approach to investigate whether genetic liability (GL) to psychopathology and childhood trauma (CT) are associated with the network structure of the emotions "cheerful," "insecure," "relaxed," "anxious," "irritated," and "down"-collected using the ESM method...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/29155541/a-festive-case-series-of-emergencies-admissions-and-friendship-at-a-busy-oral-and-maxillofacial-unit
#7
Ross Keat, Paul Leavy, Mathew Thomas
The festive season presents oral and maxillofacial surgery (OMFS) dental core trainees (DCTs) with the challenges of managing an eclectic mix of emergencies. We present three such patients in this case series. First, Patient A, a 39-year-old homeless male who presented with a maxillary extra-oral draining sinus. Secondly, Patient B, a 38-year-old intra-venous (IV) drug user who suffered pan-facial fractures following an alcohol-fuelled assault. Finally, Patient C, a 38-year-old male who sustained a left zygomatic complex fracture a week previously, in attendance for corrective surgery...
December 2016: Dental Update
https://www.readbyqxmd.com/read/29144047/evaluation-of-patient-satisfaction-in-pediatric-dermatology
#8
Sarah Ahmed, Jonathan Miller, James F Burrows, Ben Khallouq Bertha, Paul Rosen
BACKGROUND/OBJECTIVES: There remains a lack of investigation into which factors patients and families value the most in their experience at pediatric dermatology clinics. Most of the current literature on quality improvement in dermatology does not encompass the pediatric population. To determine the drivers that are most predictive of a positive patient experience, we observed the indirect relationship between several factors of the patient experience and their role in patient satisfaction...
November 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/29131656/mechanical-behavior-of-a-total-chest-wall-prosthesis-with-rib-like-features
#9
A Girotti, F Rosa, M Ferrotto, P Girotti, U Pastorino
The Department of Thoracic Surgery of the National Institute of Cancer in Milan developed a new rib-cage prosthesis which tries to combine flexibility, protection and bio-compatibility. This new replacement concept has been implanted in many patients, showing cheering results in term of reconstructions simplicity, postoperative complications reduction and patients comfort. This paper investigates and discusses in detail the mechanical behavior of the innovative rib cage prosthesis. Mechanical strength and stiffness are numerically evaluated in order to asses its limits and if it is fully compatible with patients 'normal' life...
November 13, 2017: Computer Methods in Biomechanics and Biomedical Engineering
https://www.readbyqxmd.com/read/29130869/effects-of-a-museum-based-social-prescription-intervention-on-quantitative-measures-of-psychological-wellbeing-in-older-adults
#10
Linda J Thomson, Bridget Lockyer, Paul M Camic, Helen J Chatterjee
AIMS: To assess psychological wellbeing in a novel social prescription intervention for older adults called Museums on Prescription and to explore the extent of change over time in six self-rated emotions ('absorbed', 'active', 'cheerful', 'encouraged', 'enlightened' and 'inspired'). METHODS: Participants ( n = 115) aged 65-94 years were referred to museum-based programmes comprising 10 weekly sessions, by healthcare and third sector organisations using inclusion criteria (e...
November 1, 2017: Perspectives in Public Health
https://www.readbyqxmd.com/read/29119813/school-age-children-s-perception-of-the-hospital-experience
#11
Handan Boztepe, Sevil Çınar, Ayşe Ay
In order to determine the perception of hospital experiences among school-age children's (6-12 years), a descriptive and cross-sectional study was performed in 130 children hospitalized in a pediatric hospital with different diagnoses. Data were collected using a pediatric information form, questionnaire form, scale for attitudes towards hospital and healthcare personnel, and sources of anxiety generating thoughts scale (SAGTS). Children's expectations of the nurses were to be well treated (62%), to perform painless procedures (20%), to play games together (12%), to be capable of their job (10%), and to be cheerful (10%)...
June 2017: Journal of Child Health Care: for Professionals Working with Children in the Hospital and Community
https://www.readbyqxmd.com/read/29113456/a-systematic-review-of-cost-effectiveness-studies-of-prevention-and-treatment-for-eating-disorders
#12
Long Khanh-Dao Le, Phillipa Hay, Cathrine Mihalopoulos
BACKGROUND: Eating disorders are serious mental disorders and are associated with substantial economic and social burden. The aim of this study is to undertake a systematic review of the cost-effectiveness studies of both preventive and treatment interventions for eating disorder. METHOD: Electronic databases (including the Cochrane Controlled Trial Register, MEDLINE, PsycINFO, Academic Search Complete, Global Health, CINAHL complete, Health Business Elite, Econlit, Health Policy Reference Center and ERIC) were searched for published cost-effectiveness studies of eating disorder prevention and treatment including papers published up to January 2017...
November 1, 2017: Australian and New Zealand Journal of Psychiatry
https://www.readbyqxmd.com/read/29103474/effectiveness-and-cost-effectiveness-of-double-reading-in-digital-mammography-screening-a-systematic-review-and-meta-analysis
#13
Margarita Posso, Teresa Puig, Misericòrdia Carles, Montserrat Rué, Carlos Canelo-Aybar, Xavier Bonfill
PURPOSE: Double reading is the strategy of choice for mammogram interpretation in screening programmes. It remains, however, unknown whether double reading is still the strategy of choice in the context of digital mammography. Our aim was to determine the effectiveness and cost-effectiveness of double reading versus single reading of digital mammograms in screening programmes. METHODS: We performed a systematic review by searching the PubMed, Embase, and Cochrane Library databases up to April 2017...
November 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/29052044/the-cost-effectiveness-of-exercise-based-cardiac-rehabilitation-a-systematic-review-of-the-characteristics-and-methodological-quality-of-published-literature
#14
REVIEW
Katherine Edwards, Natasha Jones, Julia Newton, Charlie Foster, Andrew Judge, Kate Jackson, Nigel K Arden, Rafael Pinedo-Villanueva
AIM: This descriptive review aimed to assess the characteristics and methodological quality of economic evaluations of cardiac rehabilitation (CR) programs according to updated economic guidelines for healthcare interventions. Recommendations will be made to inform future research addressing the impact of a physical exercise component on cost-effectiveness. METHODS: Electronic databases were searched for economic evaluations of exercise-based CR programs published in English between 2000 and 2014...
October 19, 2017: Health Economics Review
https://www.readbyqxmd.com/read/29032493/disease-modifying-therapies-for-multiple-sclerosis-a-systematic-literature-review-of-cost-effectiveness-studies
#15
REVIEW
Sergio Iannazzo, Ange-Christelle Iliza, Louise Perrault
INTRODUCTION AND OBJECTIVE: Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system. MS is considered incurable; however, disease treatment has advanced significantly over the past several decades with the introduction of disease-modifying therapies (DMTs). The current study reviewed the cost-effectiveness analyses of DMTs in relapsing-remitting MS (RRMS) patients. METHODS: A systematic literature search of bibliographic databases was conducted to identify economic evaluations published after 2007...
October 14, 2017: PharmacoEconomics
https://www.readbyqxmd.com/read/28974863/a-feasibility-study-on-the-use-of-tomotherapy-megavoltage-computed-tomography-images-for-palliative-patient-treatment-planning
#16
Yunfei Hu, Mikel Byrne, Ben Archibald-Heeren, Matthew Squires, Amy Teh, Kylie Seiffert, Sonja Cheers, Yang Wang
Dedicated rapid access palliative radiation therapy improves patients' access to care, allowing more timely treatment which would positively impact on quality of life. The TomoTherapy (Accuray, Sunnyvale, CA) system provides megavoltage (MV) fan-beam computed tomography (FBCT) as the image guidance technique, and a module called "statRT" that allows the use of these MV FBCT images for direct planning. The possibility of using this imaging modality for palliative radiotherapy treatment planning is assessed against accepted planning CT standards by performing tests following AAPM TG 66 and an end-to-end measurement...
July 2017: Journal of Medical Physics
https://www.readbyqxmd.com/read/28933921/are-you-ready-to-have-fun-the-spanish-state-form-of-the-state-trait-cheerfulness-inventory
#17
Raúl López-Benítez, Alberto Acosta, Juan Lupiáñez, Hugo Carretero-Dios
Although cheerfulness, seriousness, and bad mood as traits have been widely studied as the basis of sense of humor, data are scarce regarding the same dimensions as states. In this study, we adapted the state form of the State-Trait-Cheerfulness Inventory (STCI-S) into Spanish. At the same time, we empirically tested new predictions. We assessed 5 independent samples accounting for 1,029 participants (647 women) with ages ranging from 18 to 78 years. We confirmed the 3-dimensional structure as well as a strong measurement invariance between men and women...
September 21, 2017: Journal of Personality Assessment
https://www.readbyqxmd.com/read/28925508/the-cost-effectiveness-of-oral-health-interventions-a-systematic-review-of-cost-utility-analyses
#18
Ruvini M Hettiarachchi, Sanjeewa Kularatna, Martin J Downes, Joshua Byrnes, Jeroen Kroon, Ratilal Lalloo, Newell W Johnson, Paul A Scuffham
OBJECTIVES: To assess the usage of cost-utility analysis (CUA) in oral health interventions and to evaluate the methods used and the reporting quality of CUA in publications on oral health interventions. METHODS: A systematic review was performed on literature published between 2000 and 2016 where cost-utility analyses of oral health interventions were included. The reporting quality of these oral health CUAs was assessed against the Consolidated Health Economic Evaluation Reporting Standards (CHEERS) checklist...
September 19, 2017: Community Dentistry and Oral Epidemiology
https://www.readbyqxmd.com/read/28923574/a-systematic-review-of-health-economic-evaluation-in-adjuvant-breast-radiotherapy-quality-counted-by-numbers
#19
Chris Monten, Liv Veldeman, Nick Verhaeghe, Yolande Lievens
BACKGROUND: Evolving practice in adjuvant breast radiotherapy inevitably impacts healthcare budgets. This is reflected in a rise of health economic evaluations (HEE) in this domain. The available HEE literature was analysed qualitatively and quantitatively, using available instruments. METHODS: HEEs published between 1/1/2000 and 31/10/2016 were retrieved through a systematic search in Medline, Cochrane and Embase. A quality-assessment using CHEERS (Consolidated Health Economic Evaluation Reporting Standards) was translated into a quantitative score and compared with Tufts Medical Centre CEA registry and Quality of Health Economic Studies (QHES) results...
September 15, 2017: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/28914229/clinical-effectiveness-and-cost-effectiveness-of-beta-interferon-and-glatiramer-acetate-for-treating-multiple-sclerosis-systematic-review-and-economic-evaluation
#20
G J Melendez-Torres, Peter Auguste, Xavier Armoiry, Hendramoorthy Maheswaran, Rachel Court, Jason Madan, Alan Kan, Stephanie Lin, Carl Counsell, Jacoby Patterson, Jeremy Rodrigues, Olga Ciccarelli, Hannah Fraser, Aileen Clarke
BACKGROUND: At the time of publication of the most recent National Institute for Health and Care Excellence (NICE) guidance [technology appraisal (TA) 32] in 2002 on beta-interferon (IFN-β) and glatiramer acetate (GA) for multiple sclerosis, there was insufficient evidence of their clinical effectiveness and cost-effectiveness. OBJECTIVES: To undertake (1) systematic reviews of the clinical effectiveness and cost-effectiveness of IFN-β and GA in relapsing-remitting multiple sclerosis (RRMS), secondary progressive multiple sclerosis (SPMS) and clinically isolated syndrome (CIS) compared with best supportive care (BSC) and each other, investigating annualised relapse rate (ARR) and time to disability progression confirmed at 3 months and 6 months and (2) cost-effectiveness assessments of disease-modifying therapies (DMTs) for CIS and RRMS compared with BSC and each other...
September 2017: Health Technology Assessment: HTA
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