Read by QxMD icon Read


Kathleen Heng, Abbey Thompson, David Chu, David M Kingsley
No abstract text is available yet for this article.
October 20, 2016: Lab Animal
Asrul Akmal Shafie, Chin Hui Ng, Yui Ping Tan, Nathorn Chaiyakunapruk
BACKGROUND: Insulin analogues have a pharmacokinetic advantage over human insulin and are increasingly used to treat diabetes mellitus. A summary of their cost effectiveness versus other available treatments was required. OBJECTIVE: Our objective was to systematically review the published cost-effectiveness studies of insulin analogues for the treatment of patients with type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus (T2DM). METHODS: We searched major databases and health technology assessment agency reports for economic evaluation studies published up until 30 September 2015...
October 17, 2016: PharmacoEconomics
Bastiaan Boh, Anita Jansen, Ineke Clijsters, Chantal Nederkoorn, Lotte H J M Lemmens, Gerasimos Spanakis, Anne Roefs
Cognitions and emotions are considered important determinants of eating behaviour in cognitive behavioural models of obesity. Ecological data on these determinants is still limited. The present study investigated cognitions and emotions of overweight (n = 57) and healthy-weight (n = 43) participants via Ecological Momentary Assessment. It was found that eating-related cognitions mainly focused on desire and taste. Unexpectedly, dysfunctional cognitions (i.e., thoughts that may promote overeating) did not occur more often for overweight participants in almost all cases...
October 4, 2016: Behaviour Research and Therapy
Natalie E Zlebnik, Joseph F Cheer
The endocannabinoid (eCB) system has emerged as one of the most important mediators of physiological and pathological reward-related synaptic plasticity. eCBs are retrograde messengers that provide feedback inhibition, resulting in the suppression of neurotransmitter release at both excitatory and inhibitory synapses, and they serve a critical role in the spatiotemporal regulation of both short- and long-term synaptic plasticity that supports adaptive learning of reward-motivated behaviors. However, mechanisms of eCB-mediated synaptic plasticity in reward areas of the brain are impaired following exposure to drugs of abuse...
October 5, 2016: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
L Bryans
I have just read the thoroughly depressing article, 'Ordinariness in nursing: a study'(Clinical, June 16). Dissections and post mortems are, by comparison, cheerful.
July 7, 1993: Nursing Standard
Antony Sheehan
I once heard of a man who was given a brand new car for Christmas.
December 18, 1991: Nursing Standard
(no author information available yet)
The cheap and cheerful Mills and Boon medical romances are always good for a bit of escapism when you've had a particularly hard day. How accurately these popular paperbacks portray life on a typical hospital ward is questionable, but then they make no claim to documentary status, as Carrie Howse points out in her article on the image of nurses ( page 20 ).
December 11, 1991: Nursing Standard
George Mike
The Government's 'care in the community' policy is now a year old. There were many supporters who saw in it official confirmation that large, dehumanising, health and social care institution were finally coming to an end. But others thought that it was mainly a device to allow the Department of Health to shuffle off responsibility for an increasingly expensive area of care.
March 30, 1994: Nursing Standard
Thomas Politzer, Amy Berryman, Karen Rasavage, Lawrence Snell, Allan Weintraub, Donald J Gerber
BACKGROUND: Oculomotor deficits in smooth pursuit, saccades, vestibular-ocular reflex (VOR), vergence, and fixation are common problems seen after moderate to severe traumatic brain injury (TBI). No scale currently exists to rate all of these together. The Craig Hospital Eye Evaluation Rating Scale (CHEERS) was designed to systematically quantify frequency and severity of eye movement deficits in TBI. OBJECTIVE: To assess the intra- and interrater reliability of a new rating scale for detecting the presence and degree of 5 oculomotor abnormalities after TBI...
September 21, 2016: PM & R: the Journal of Injury, Function, and Rehabilitation
(no author information available yet)
Cheers, John: Man Jordan, South Western Area Liaison Staff Officer for the St John Ambulance, was invested into the Order of St John in recognition of her 20 years service with the organisation. Mrs Jordan works as a Property and Services Officer with the Royal College of Nursing.
June 5, 1991: Nursing Standard
Jonathan Minton, Mark Green, Gerry McCartney, Richard Shaw, Laura Vanderbloemen, Kate Pickett
No abstract text is available yet for this article.
September 17, 2016: International Journal of Epidemiology
Jade Shepherd
Through an examination of previously unseen archival records, including patients' letters, this article examines the treatment and experiences of patients in late Victorian Broadmoor Criminal Lunatic Asylum and stakes the place of this institution within the broader history of therapeutic regimes in British asylums. Two main arguments are put forth. The first relates to the evolution of treatment in Victorian asylums. Historians tend to agree that in the 1860s and 1870s 'psychiatric pessimism' took hold, as the optimism that had accompanied the growth of moral treatment, along with its promise of a cure for insanity, abated...
October 2016: Medical History
Anneli Stranz, Renita Sörensdotter
Using ethnographic data collected from nursing homes in England and Sweden, this article analyzes how a person-centered approach to dementia care has been interpreted in two different contexts. Based on typical elements of person-centered care identified in previous research, the analysis examines environmental changes and the way care is performed. A discourse of person-centered care is articulated at both nursing homes, which aim to create a good environment and care practice for people with dementia. Although we found similarities in how good care was understood at the two homes, we also found important differences...
August 2016: Journal of Aging Studies
Muhammad Nidzhom Zainol Abidin, Pei Sean Goh, Ahmad Fauzi Ismail, Mohd Hafiz Dzarfan Othman, Hasrinah Hasbullah, Noresah Said, Siti Hamimah Sheikh Abdul Kadir, Fatmawati Kamal, Mohd Sohaimi Abdullah, Be Cheer Ng
Poly (citric acid)-grafted-MWCNT (PCA-g-MWCNT) was incorporated as nanofiller in polyethersulfone (PES) to produce hemodialysis mixed matrix membrane (MMM). Citric acid monohydrate was polymerized onto the surface of MWCNTs by polycondensation. Neat PES membrane and PES/MWCNTs MMMs were fabricated by dry-wet spinning technique. The membranes were characterized in terms of morphology, pure water flux (PWF) and bovine serum albumin (BSA) protein rejection. The grafting yield of PCA onto MWCNTs was calculated as 149...
November 1, 2016: Materials Science & Engineering. C, Materials for Biological Applications
Adem Can, Douglas O Frost, Roger Cachope, Joseph F Cheer, Todd D Gould
Chronic lithium treatment effectively reduces behavioral phenotypes of mania in humans and rodents. The mechanisms by which lithium exerts these actions are poorly understood. Pre-clinical and clinical evidence have implicated increased mesolimbic dopamine (DA) neurotransmission with mania. We used fast-scan cyclic voltammetry to characterize changes in extracellular DA concentrations in the nucleus accumbens (NAc) core evoked by 20 and 60 Hz electrical stimulation of the ventral tegmental area (VTA) in C57BL6/J mice treated either acutely or chronically with lithium...
August 11, 2016: Journal of Neurochemistry
Nina Lopatina, Michael A McDannald, Clay V Styer, Jacob F Peterson, Brian F Sadacca, Joseph F Cheer, Geoffrey Schoenbaum
UNLABELLED: The orbitofrontal cortex (OFC) has been broadly implicated in the ability to use the current value of expected outcomes to guide behavior. Although value correlates have been prominently reported in lateral OFC, they are more often associated with more medial areas. Further, recent studies in primates have suggested a dissociation in which the lateral OFC is involved in credit assignment and representation of reward identity and more medial areas are critical to representing value...
August 10, 2016: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
Adem Can, Panos Zanos, Ruin Moaddel, Hye Jin Kang, Katinia S S Dossou, Irving W Wainer, Joseph F Cheer, Douglas O Frost, Xi-Ping Huang, Todd D Gould
Following administration at subanesthetic doses, (R,S)-ketamine (ketamine) induces rapid and robust relief from symptoms of depression in treatment-refractory depressed patients. Previous studies suggest that ketamine's antidepressant properties involve enhancement of dopamine (DA) neurotransmission. Ketamine is rapidly metabolized to (2S,6S)- and (2R,6R)-hydroxynorketamine (HNK), which have antidepressant actions independent of N-methyl-d-aspartate glutamate receptor inhibition. These antidepressant actions of (2S,6S;2R,6R)-HNK, or other metabolites, as well as ketamine's side effects, including abuse potential, may be related to direct effects on components of the dopaminergic (DAergic) system...
October 2016: Journal of Pharmacology and Experimental Therapeutics
Stephanie DeFlorio-Barker, Timothy J Wade, Rachael M Jones, Lee S Friedman, Coady Wing, Samuel Dorevitch
BACKGROUND: The burden of illness can be described by addressing both incidence and illness severity attributable to water recreation. Monetized as cost, attributable disease burden estimates can be useful for environmental management decisions. OBJECTIVES: To characterize the disease burden attributable to water recreation using data from two cohort studies using a cost of illness (COI) approach and to estimate the largest drivers of the disease burden of water recreation...
July 26, 2016: Environmental Health Perspectives
Peter Auguste, Alexander Tsertsvadze, Rachel Court, Joshua Pink
BACKGROUND: Timely diagnosis and treatment of latent tuberculosis infection (LTBI) through screening remains a key public health priority. Although globally it is recommended to screen people at high risk of developing TB, the economic evidence underpinning these recommendations is limited. This review critically appraised studies that had used a decision-analytical modelling framework to estimate the cost-effectiveness of interferon gamma release assays (IGRAs) compared to tuberculin skin test (TST) for detecting LTBI in high risk populations...
July 2016: Tuberculosis
Renee Cockerham, Shaolin Liu, Roger Cachope, Emi Kiyokage, Joseph F Cheer, Michael T Shipley, Adam C Puche
UNLABELLED: The efficacy of neurotransmission depends on multiple factors, including presynaptic vesicular release of transmitter, postsynaptic receptor populations and clearance/inactivation of the transmitter. In the olfactory bulb (OB), short axon cells (SACs) form an interglomerular circuit that uses GABA and dopamine (DA) as cotransmitters. Selective optical activation of SACs causes GABA and DA co-release, resulting in a fast, postsynaptic GABA inhibitory response and a slower G-protein-coupled DA rebound excitation...
July 20, 2016: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"