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https://www.readbyqxmd.com/read/28745818/is-repeat-botulinum-toxin-a-injection-valuable-for-neurogenic-detrusor-overactivity-a-systematic-review-and-meta-analysis
#1
REVIEW
Jianshu Ni, Xiaohu Wang, Nailong Cao, Jiemin Si, Baojun Gu
AIM: To investigate the value of repeat botulinum toxin A (BTX-A) injections in patients with neurogenic detrusor overactivity (NDO). METHODS: We searched the PubMed, EMBASE, and EBSCO databases for articles published until June 2016. Studies that reported the efficacy and safety of repeat BTX-A injections for adult patients with NDO were eligible. The effect size for each outcome was calculated as the standardized mean difference ± standard error and 95% confidence interval, and was graded as small, >0...
July 26, 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/28741292/effect-of-mdp-based-silane-and-different-surface-conditioner-methods-on-bonding-of-resin-cements-to-zirconium-framework
#2
Hatice Özdemir, Nuran Yanikoğlu, Nurdan Sağsöz
PURPOSE: To determine the shear bond strength (SBS) between zirconium framework and resin cements after different surface conditioner methods and after application of 10-methacryloyloxydecyl dihydrogen phosphate (MDP) based silane and a bonding agent mix. MATERIALS AND METHODS: 128 disc-shaped zirconium-oxide specimens were prepared. Specimens were placed in autopolymerizing acrylic resin. The bonding surface of specimens was smoothed consecutively with 600-, 800-, and 1200-grit silicon carbide papers under water cooling...
July 24, 2017: Journal of Prosthodontics: Official Journal of the American College of Prosthodontists
https://www.readbyqxmd.com/read/28738834/the-value-of-99m-tc-methylene-diphosphonate-single-photon-emission-computed-tomography-computed-tomography-in-diagnosis-of-fibrous-dysplasia
#3
Linqi Zhang, Qiao He, Wei Li, Rusen Zhang
BACKGROUND: Fibrous dysplasia (FD) is a rare benign bone disorder in which the normal bone is replaced by immature fibro-osseous tissue. However, some case reports have reported that FD showed significantly increased (99m)Tc-methylene diphosphonate ((99m)Tc-MDP) uptake on whole-body bone scintigraphy (WBS), which may mimic bone metastasis or skeletal involvement of the patients with known cancer. Thus, the purpose of present study is to observe the reliable characteristics and usefulness of single photon emission computed tomography/computed tomography (SPECT/CT) for the diagnosis of FD...
July 24, 2017: BMC Medical Imaging
https://www.readbyqxmd.com/read/28737581/intense-99mtc-mdp-activity-in-an-elongated-sagging-gallbladder-with-a-partially-calcified-gallstone
#4
Xiangcheng Wang, Xia Bai, Weina Zhou, Xiyan Hao, Xuemei Wang
Intense activity was noted in the right middle abdomen on whole-body Tc-MDP bone scan images, which were obtained in a 78-year-old woman who had back pain. Further SPECT/CT images demonstrated that the intense activity was located in an elongated gallbladder. Partially calcified gallstone was also revealed on SPECT/CT images. Unexpectedly, the gallbladder activity was from the radioactive bile inside the gallbladder lumen, whereas the partially calcified gallstone was relatively photopenic.
July 22, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28736006/advantages-of-epidural-analgesia-on-pulmonary-functions-in-liver-transplant-donors
#5
H K Atalan, B Gucyetmez, R Donmez, A Kargi, K Y Polat
OBJECTIVE: Epidural analgesia (EA) has positive effects on anesthetic requirement, blood loss, postoperative analgesia, and pulmonary function tests (PFTs). The purpose of the present study was to investigate the effect of EA on postoperative PFTs in liver transplant donors (LTDs). METHODS: In the present study, 66 LTDs were classified as total intravenous anesthesia (TIVA) and TIVA+EA groups. Patient's age, sex, body mass index, induction and maintenance dose of propofol (IDP and MDP), operation duration, forced expiratory volume in 1 second (FEV1), forced vital capacity (FVC), FEV1/FVC ratio, visual analog scale (VAS), atelectasis scores, and lengths of intensive care unit (ICU) and hospital stays were recorded...
July 2017: Transplantation Proceedings
https://www.readbyqxmd.com/read/28726777/humanin-g-hng-protects-age-related-macular-degeneration-amd-transmitochondrial-arpe-19-cybrids-from-mitochondrial-and-cellular-damage
#6
Sonali Nashine, Pinchas Cohen, Marilyn Chwa, Stephanie Lu, Anthony B Nesburn, Baruch D Kuppermann, M Cristina Kenney
Age-related macular degeneration (AMD) ranks third among the leading causes of visual impairment with a blindness prevalence rate of 8.7%. Despite several treatment regimens, such as anti-angiogenic drugs, laser therapy, and vitamin supplementation, being available for wet AMD, to date there are no FDA-approved therapies for dry AMD. Substantial evidence implicates mitochondrial damage and retinal pigment epithelium (RPE) cell death in the pathogenesis of AMD. However, the effects of AMD mitochondria and Humanin G (HNG), a more potent variant of the mitochondrial-derived peptide (MDP) Humanin, on retinal cell survival have not been elucidated...
July 20, 2017: Cell Death & Disease
https://www.readbyqxmd.com/read/28725986/patterns-of-alcohol-consumption-and-risk-of-falls-in-older-adults-a-prospective-cohort-study
#7
R Ortolá, E García-Esquinas, I Galán, P Guallar-Castillón, E López-García, J R Banegas, F Rodríguez-Artalejo
Falls are a major health problem in older adults, but their relationship with alcohol consumption in this population remains unclear. In a cohort with 2170 older adults followed up for 3.3 years, both moderate drinking and the Mediterranean drinking pattern were associated with a lower risk of falls and injurious falls. INTRODUCTION: This study aims to examine the association between certain patterns of alcohol consumption, including the Mediterranean drinking pattern (MDP), and the risk of falls in older adults...
July 19, 2017: Osteoporosis International
https://www.readbyqxmd.com/read/28721303/value-of-99m-tc-mdp-spect-ct-and-18-f-fdg-pet-ct-scanning-in-the-evaluation-of-malignantly-transformed-fibrous-dysplasia
#8
Wei-Jun Wei, Zhen-Kui Sun, Chen-Tian Shen, Xin-Yun Zhang, Juan Tang, Hong-Jun Song, Zhong-Ling Qiu, Quan-Yong Luo
Although fibrous dysplasia is not considered a potentially premalignant disorder, malignant transformation occurs. Because of its rarity, radiographic features of malignantly transformed fibrous dysplasia on cross-sectional imaging modalities are less recognized, making diagnosis and differential diagnosis of the disease quite difficult in clinical practice. In this study, we analyzed the clinical characteristics, imaging features, pathology findings and surgery strategies of 19 malignantly transformed fibrous dysplasia...
2017: American Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/28719445/adefovir-induced-hypophosphatemic-osteomalacia-mimicking-bone-metastases-from-primary-hepatocarcinoma
#9
Wei-Jun Wei, Zhen-Kui Sun, Chen-Tian Shen, Zhong-Ling Qiu, Quan-Yong Luo
Adefovir-induced hypophosphatemic osteomalacia in the context of hepatocarcinoma is rare and needs to be differentiated from metastatic hepatocarcinoma. We here report a case of severe osteomalacia whose focal uptakes of radiotracer on the Tc-MDP SPECT/CT images mimicked that of metastatic hepatocarcinoma.
July 17, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28708377/membrane-association-dictates-ligand-specificity-for-the-innate-immune-receptor-nod2
#10
Amy K Schaefer, James E Melnyk, Michael Baksh, Klare M Lazor, M G Finn, Catherine Leimkuhler Grimes
The human gut must regulate its immune response to resident and pathogenic bacteria, numbering in the trillions. The peptidoglycan component of the bacterial cell wall is a dense and rigid structure that consists of polymeric carbohydrates and highly crosslinked peptides which offers protection from the host and surrounding environment. Nucleotide-binding oligomerization domain-containing protein 2 (NOD2), a human membrane-associated innate immune receptor found in the gut epithelium and mutated in an estimated 30% of Crohn's disease patients, binds to peptidoglycan fragments and initiates an immune response...
July 14, 2017: ACS Chemical Biology
https://www.readbyqxmd.com/read/28708083/ten-year-trends-1999-2010-of-adherence-to-the-mediterranean-diet-among-the-balearic-islands-adult-population
#11
Maria Del Mar Bibiloni, Mónica González, Alicia Julibert, Isabel Llompart, Antoni Pons, Josep A Tur
The aim of this work was to assess ten-year trends (1999-2010) of adherence to the Mediterranean dietary pattern (MDP) among the Balearic Islands' adult population. Two independent cross-sectional dietary surveys (1999-2000, n = 1200 and 2009-2010 n = 1388, including participants aged 16-65 years) were carried out in the Balearic Islands, Spain. Dietary habits were assessed by means of two 24 h diet recalls and a validated semi-quantitative food-frequency questionnaire that covers 145 food items. Adherence to the MDP was defined according to a score constructed considering the consumption of nine MDP characteristic components: high monounsaturated fatty acids:saturated fatty acids (MUFA:SFA) ratio, moderate ethanol consumption, high legumes, cereals and roots, fruits, vegetables, and fish consumption, and low consumption of meat and milk...
July 14, 2017: Nutrients
https://www.readbyqxmd.com/read/28696362/trends-of-adherence-to-the-mediterranean-dietary-pattern-in-northern-italy-from-2010-to-2016
#12
Alessandro Leone, Alberto Battezzati, Ramona De Amicis, Giulia De Carlo, Simona Bertoli
Little information is available on the trends of adherence to the Mediterranean dietary pattern (MDP). This study investigates food consumption trends from 2010 to 2016 in subjects living in Northern Italy. A cross-sectional study of 8584 subjects enrolled between January 2010 and December 2016 was conducted. Socio-demographic, nutrition and lifestyle characteristics were collected. A 14-item questionnaire was used to evaluate adherence to MDP. Multivariable Poisson regression was used to evaluate the trends of and the determinants for the adherence to MDP...
July 11, 2017: Nutrients
https://www.readbyqxmd.com/read/28684703/western-and-mediterranean-dietary-patterns-and-physical-activity-and-fitness-among-spanish-older-adults
#13
Maria Del Mar Bibiloni, Alicia Julibert, Emma Argelich, Raquel Aparicio-Ugarriza, Gonzalo Palacios, Antoni Pons, Marcela Gonzalez-Gross, Josep A Tur
Objectives: To assess prevailing food patterns, and its association with physical activity and fitness among Spanish older adults. Methods: Cross-sectional study in Spain, collecting data from a sample (n = 380; 54% female) aged 55-80 years (men) and 60-80 years (women) with no previously documented cardiovascular disease. Body weight, body fat and waist circumference were assessed. Physical activity performed was measured using the Minnesota Leisure-time Physical Activity Questionnaire (LTPA). Physical fitness was assessed using a validated physical fitness test battery...
July 6, 2017: Nutrients
https://www.readbyqxmd.com/read/28682543/-establishment-and-mechanisms-of-chemical-interaction-between-phosphate-monomer-and-zirconia-model
#14
Lu Zhicen, Xie Haifeng, Zhang Feimin, Zhang Huaiqin, Chen Chen
OBJECTIVE: To analyze chemical mechanism of bonding improvement of zirconia via 10-methacryloyloxydecyl dihydrogen phosphate (MDP) conditioning. METHODS: Various models were created for tetragonal zirconia crystals, molecular MDP, and MDP complex, and tetragonal zirconia crystal. Thermodynamic methods were used to analyze configuration between MDP and tetragonal zirconia crystal through calculation of their Gibbs free energy values and equilibrium constants. RESULTS: Two potential configurations (double- and single-coordinate) may occur between MDP and ZrO2 crystal clusters...
April 1, 2017: Hua Xi Kou Qiang Yi Xue za Zhi, Huaxi Kouqiang Yixue Zazhi, West China Journal of Stomatology
https://www.readbyqxmd.com/read/28680220/myofascial-pain-syndrome-on-tc99m-mdp-bone-scintigraphy
#15
Rola Aatif Hasan Hussain, Ammar Mohammed Saeed Ali, K Manivannan, S K Chirala
No abstract text is available yet for this article.
July 2017: Indian Journal of Nuclear Medicine: IJNM: the Official Journal of the Society of Nuclear Medicine, India
https://www.readbyqxmd.com/read/28680206/avascular-necrosis-of-talus-diagnosed-on-tc-99m-mdp-bone-scan
#16
Ashish R Kamra, Shwetal U Pawar, Suruchi Shetye, Preeti R Singh
Avascular necrosis (AVN) of bone is defined as the cellular death of bone components due to the interruption of the blood supply; the bone structures then collapse, resulting in pain and loss of joint function. Magnetic resonance imaging (MRI) is the gold standard to diagnose AVN. We present an unusual case of AVN of talus in a patient of thalassemia major that was diagnosed on the Tc-99m MDP bone scan with equivocal findings on MRI. Key Message: The diagnosis of AVN is primarily done using radiological investigations...
July 2017: Indian Journal of Nuclear Medicine: IJNM: the Official Journal of the Society of Nuclear Medicine, India
https://www.readbyqxmd.com/read/28680204/role-of-99m-tc-mdp-bone-scan-in-delineation-of-ischaemic-zone-in-cases-of-severe-frostbite
#17
Arun Ravi John, Anurag Jain, Braj Kishore, Aniruddha G Pandit
Frostbite or cold burn is the medical condition in which localized damage is caused to exposed skin and subcutaneous tissue due to freezing. Frostbite most likely involves body parts farthest from the heart and those with large exposed areas. At or below 0 °C (32 °F), blood vessels close to the skin start to constrict, and blood is shunted away from the extremities via the physiological feedback action of glomus bodies. This peripheral vasoconstriction helps to conserve core body temperature. In extreme cold, or when certain parts of the body are exposed to cold conditions for long periods, this protective mechanism can reduce blood flow in some areas of the body to dangerously low levels...
July 2017: Indian Journal of Nuclear Medicine: IJNM: the Official Journal of the Society of Nuclear Medicine, India
https://www.readbyqxmd.com/read/28678323/expression-and-prognostic-roles-of-magnesium-dependent-phosphatase-1-in-gastric-cancer
#18
Y Chen, J Lin, M Yang, C-W Xu, B-Z Chen, X-J Li, W-F Zhu, W-D Fu, H Yu, M-G Ying, G Chen
OBJECTIVE: Gastric cancer is a leading cause of cancer deaths and has a poor prognosis after diagnosis. Previous studies showed that Magnesium-Dependent Phosphatase-1 (MDP-1) might be a key component for glycosylation in human protein repair, and an alteration of its function has been involved in some aspects of cellular metabolic networks linked to either normal or pathological processe. In this study, we investigate the MDP-1 status in patients with gastric carcinoma, and determine the potential relationship between MDP-1 and clinical outcome...
June 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28658623/nod2-suppresses-colorectal-tumorigenesis-via-downregulation-of-the-tlr-pathways
#19
S M Nashir Udden, Lan Peng, Jia-Liang Gan, John M Shelton, James S Malter, Lora V Hooper, Md Hasan Zaki
Although NOD2 is the major inflammatory bowel disease susceptibility gene, its role in colorectal tumorigenesis is poorly defined. Here, we show that Nod2-deficient mice are highly susceptible to experimental colorectal tumorigenesis independent of gut microbial dysbiosis. Interestingly, the expression of inflammatory genes and the activation of inflammatory pathways, including NF-κB, ERK, and STAT3 are significantly higher in Nod2(-/-) mouse colons during colitis and colorectal tumorigenesis, but not at homeostasis...
June 27, 2017: Cell Reports
https://www.readbyqxmd.com/read/28657567/bone-scan-in-painful-knee-arthroplasty-obsolete-or-actual-examination
#20
Giuseppe Niccoli, Domenico Mercurio, Fabrizio Cortese
ptic loosening, instability and infection are the major causes of TKA failure. For many years, nuclear medicine (NM) imaging was helpful to frame a painful total joint arthroplasty. The differentiation of septic from aseptic prosthetic loosening is critical. The latest AAOS guidelines to detect periprosthetic joint infection (PJI) restrict the role of NM scintigraphy. On the other hand, several studies suggest that NM imaging plays an important role in the evaluation of patients with painful prosthesis, but its specificity in differentiating aseptic loosening from infection is low...
June 7, 2017: Acta Bio-medica: Atenei Parmensis
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