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https://www.readbyqxmd.com/read/28533650/extensive-visceral-calcification-demonstrated-on-99m-tc-mdp-bone-scan-in-patient-with-carcinoma-penis-and-hypercalcemia-of-malignancy
#1
Sunny J Gandhi, Bhavdeep Rabadiya
Hypercalcemia is a common life-threatening complication associated with several malignancies. Parathyroid-related peptide has been shown to cause hypercalcemia in several solid tumors but rarely in penile cancer. We report a case of penile cancer with hypercalcemia causing metastatic visceral calcification in lungs, liver, and stomach detected on bone scan without significant abnormalities on CT scan.
April 2017: Indian Journal of Nuclear Medicine: IJNM: the Official Journal of the Society of Nuclear Medicine, India
https://www.readbyqxmd.com/read/28533011/effect-of-surface-treatments-on-repair-with-composite-resin-of-a-partially-monoclinic-phase-transformed-yttrium-stabilized-tetragonal-zirconia
#2
Beatriz Regalado Galvão Ribeiro, Marilia Regalado Galvão Rabelo Caldas, Antonio Alves Almeida, Renata Garcia Fonseca, Gelson Luis Adabo
STATEMENT OF PROBLEM: Studies of composite resin repairs of yttrium-tetragonal zirconia polycrystal (Y-TZP) are usually performed in its tetragonal phase, but it may be partially transformed into a monoclinic phase in a clinical fracture. PURPOSE: The purpose of this in vitro study was to evaluate the effect of airborne-particle abrasion (APA) and a bonding agent on the shear bond strength (SBS) between a composite resin and hydrothermally aged Y-TZP. MATERIAL AND METHODS: Specimens (7...
May 20, 2017: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/28527812/adhesive-interfacial-characteristics-and-the-related-bonding-performance-of-four-self-etching-adhesives-with-different-functional-monomers-applied-to-dentin
#3
Ruirui Wang, Yilin Shi, Tingting Li, Yueping Pan, Yu Cui, Wenwei Xia
OBJECTIVES: To examine the interfacial chemical and morphological characteristics of four self-etching adhesives bonded to dentin with different functional monomers. Further, to evaluate the effects of this interaction between functional monomers and dentin on short-term in vitro bonding performance of the four adhesives. METHODS: Clearfil SE Bond (CSE) and Scotchbond Universal (SU) containing 10-methacryloxydecyl dihydrogen phosphate (10-MDP), Optibond XTR (OX) containing glycero-phosphate dimethacrylate (GPDM), and Adper Easy One (AEO) containing 6-methacryloyloxyhexyl dihydrogen phosphate (6-MHP) were applied to the dentin surface according to the instructions supplied with each...
May 17, 2017: Journal of Dentistry
https://www.readbyqxmd.com/read/28514760/clinical-study-of-99mtc-3p-rgd2-peptide-imaging-in-osteolytic-bone-metastasis
#4
Guoqiang Shao, Wei Gu, Muhong Guo, Shiming Zang, Jinjing Fu, Shuang Liu, Feng Wang, Zizheng Wang
OBJECTIVE: To investigate the value of integrin αvβ3 targeted imaging with 99mTc-HYNIC-PEG4-E[PEG4-c(RGDfk)]2 (99mTc-3P-RGD2) as a radiotracer in dectecting osteolytic bone metastases. METHODS: This is a retrospective study involving a cohort of 69 consecutive patients including 59 with lung cancer and 10 with other cancers. Patients were required to receive whole body scan (WBS) and regional SPECT/CT imaging with 99mTc-3P-RGD2 (RGD imaging) and 99mTc-MDP (MDP imaging) as a radiotracer successively within days...
April 27, 2017: Oncotarget
https://www.readbyqxmd.com/read/28494020/pannexin-3-regulates-proliferation-and-differentiation-of-odontoblasts-via-its-hemichannel-activities
#5
Tsutomu Iwamoto, Takashi Nakamura, Masaki Ishikawa, Keigo Yoshizaki, Asuna Sugimoto, Hiroko Ida-Yonemochi, Hayato Ohshima, Masahiro Saito, Yoshihiko Yamada, Satoshi Fukumoto
Highly coordinated regulation of cell proliferation and differentiation contributes to the formation of functionally shaped and sized teeth; however, the mechanism underlying the switch from cell cycle exit to cell differentiation during odontogenesis is poorly understood. Recently, we identified pannexin 3 (Panx3) as a member of the pannexin gap junction protein family from tooth germs. The expression of Panx3 was predominately localized in preodontoblasts that arise from dental papilla cells and can differentiate into dentin-secreting odontoblasts...
2017: PloS One
https://www.readbyqxmd.com/read/28482911/rapid-development-of-metastatic-pulmonary-calcifications-in-primary-hyperparathyroidism-a-case-report-and-literature-review
#6
Hui-Ming Sun, Fei Chen, Hong-Lin Yin, Xiao-Yong Xu, Hong-Bing Liu, Bei-Lei Zhao
BACKGROUND: Metastatic pulmonary calcification (MPC) is rarely reported in primary hyperparathyroidism, especially MPC develops quickly. We report such a case here with a literature review. CASE PRESENTATION: A 41-year-old woman presented with cough and dyspnea. Data from clinical, radiological, pathological, technetium ((99m)Tc)-methylene diphosphonate (MDP) bone scintillation imaging, and (99m)Tc-methoxy isobutyl isonitrile (MIBI) thyroid imaging were studied...
May 8, 2017: Diagnostic Pathology
https://www.readbyqxmd.com/read/28467265/bonding-polycrystalline-zirconia-with-10-mdp-containing-adhesives
#7
A E Llerena-Icochea, R M Costa, Afs Borges, Jfs Bombonatti, A Y Furuse
OBJECTIVE: The objective of this study was to evaluate the influence of adhesives with different 10-MDP concentrations on the shear bond strength of a resin cement to zirconia. METHODS AND MATERIALS: Six experimental adhesives were prepared with the following composition: camphorquinone, 1,2-diaminobenzene, butylhydroxytoluene, diphenyliodonium hexafluorophosphate, 2-hydroxyethyl methacrylate triethylene glycol dimethacrylate, ethoxylated bisphenol A glycol dimethacrylate, urethane dimethacrylate, bisphenol A diglycidyl methacrylate, and ethanol...
May 2017: Operative Dentistry
https://www.readbyqxmd.com/read/28461047/influence-of-cement-type-and-ceramic-primer-on-retention-of-polymer-infiltrated-ceramic-crowns-to-a-one-piece-zirconia-implant
#8
Nadja Rohr, Stefan Brunner, Sabrina Märtin, Jens Fischer
STATEMENT OF PROBLEM: The best procedure for cementing a restoration to zirconia implants has not yet been established. PURPOSE: The purpose of this in vitro study was to measure the retention of polymer-infiltrated ceramic crowns to zirconia 1-piece implants using a wide range of cements. The effect of ceramic primer treatment on the retention force was also recorded. The retention results were correlated with the shear bond strength of the cement to zirconia and the indirect tensile strength of the cements to better understand the retention mechanism...
April 28, 2017: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/28449267/evaluation-of-the-utility-of-99m-tc-mdp-bone-scintigraphy-versus-mibg-scintigraphy-and-cross-sectional-imaging-for-staging-patients-with-neuroblastoma
#9
Jean-Marc Gauguet, Tamara Pace-Emerson, Frederick D Grant, Suzanne Shusterman, Steven G DuBois, A Lindsay Frazier, Stephan D Voss
PURPOSE: Accurate staging of neuroblastoma requires multiple imaging examinations. The purpose of this study was to determine the relative contribution of (99m) Tc-methylene diphosphonate (MDP) bone scintigraphy (bone scan) versus metaiodobenzylguanidine scintigraphy (MIBG scan) for accurate staging of neuroblastoma. METHODS: A medical record search by the identified patients with neuroblastoma from 1993 to 2012 who underwent both MIBG and bone scan for disease staging...
April 27, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28435621/the-effect-of-plasma-on-shear-bond-strength-between-resin-cement-and-colored-zirconia
#10
Chan Park, Seung-Hwan Yoo, Sang-Won Park, Kwi-Dug Yun, Min-Kyung Ji, Jin-Ho Shin, Hyun-Pil Lim
PURPOSE: To investigate the effect of non-thermal atmospheric pressure plasma (NTAPP) treatment on shear bond strength (SBS) between resin cement and colored zirconia made with metal chlorides. MATERIALS AND METHODS: 60 zirconia specimens were divided into 3 groups using coloring liquid. Each group was divided again into 2 sub-groups using plasma treatment; the experimental group was treated with plasma, and the control group was untreated. The sub-groups were: N (non-colored), C (0...
April 2017: Journal of Advanced Prosthodontics
https://www.readbyqxmd.com/read/28434881/muramyl-dipeptide-based-postbiotics-mitigate-obesity-induced-insulin-resistance-via-irf4
#11
Joseph F Cavallari, Morgan D Fullerton, Brittany M Duggan, Kevin P Foley, Emmanuel Denou, Brennan K Smith, Eric M Desjardins, Brandyn D Henriksbo, Kalvin J Kim, Brian R Tuinema, Jennifer C Stearns, David Prescott, Philip Rosenstiel, Brian K Coombes, Gregory R Steinberg, Jonathan D Schertzer
Intestinal dysbiosis contributes to obesity and insulin resistance, but intervening with antibiotics, prebiotics, or probiotics can be limited by specificity or sustained changes in microbial composition. Postbiotics include bacterial components such as lipopolysaccharides, which have been shown to promote insulin resistance during metabolic endotoxemia. We found that bacterial cell wall-derived muramyl dipeptide (MDP) is an insulin-sensitizing postbiotic that requires NOD2. Injecting MDP lowered adipose inflammation and reduced glucose intolerance in obese mice without causing weight loss or altering the composition of the microbiome...
May 2, 2017: Cell Metabolism
https://www.readbyqxmd.com/read/28414171/the-effects-of-water-on-degradation-of-the-zirconia-resin-bond
#12
C Chen, Y Chen, Z Lu, M Qian, H Xie, F R Tay
OBJECTIVES: 10-methacryloyloxydecyldihydrogenphosphate (MDP) containing primers improve bonding of yttria-stabilised tetragonal zirconia (Y-TZP) to methacrylate resins. The present study investigated the role played by water in the deterioration of MDP-mediated zirconia-resin bonds. METHODS: Grit-blasted Y-TZP plates were conditioned with two MDP primers and bonded with resin for shear bond strength (SBS) testing. Additional bonded plates were aged hydrothermally and compared with unaged Y-TZP after 24hours of water-storage or 6 months of water/acid/alkali-storage...
April 13, 2017: Journal of Dentistry
https://www.readbyqxmd.com/read/28410331/the-role-of-erbin-in-gts-21-regulating-inflammtory-responses-in-mdp-stimulated-macrophages
#13
Xiao-Jing Wu, Xu-Ming Yang, Xue-Min Song, Yang Xu, Jian-Guo Li, Yan-Lin Wang, Zong-Ze Zhang, Lin-Li Le, Hui Liang, Yin Zhang
OBJECTIVE: To explore the role of Erbin protein and nucleotide-binding oligomerization domain 2/receptor-interacting serine/threonine protein kinases (NOD2/RICK) in GTS-21 activating cholinergic anti-inflammatory pathway. METHODS: Experiments were randomly divided into four groups: normal control (NC) group, muramyl dipeptide (MDP) group, 10 μg/mL MDP, GTS-21 (GTS) group, 10 μg/mL MDP plus 50 μg/mL GTS-21 (α7 nAChRs agonist), Erbin shRNA interference (sh-Erbin) group: sh-Erbin RNA plus 10 μg/mL MDP and 50 μg/mL GTS-21...
May 2017: Shock
https://www.readbyqxmd.com/read/28402733/effect-of-surface-treatment-silane-and-universal-adhesive-on-microshear-bond-strength-of-nanofilled-composite-repairs
#14
I A Fornazari, I Wille, E M Meda, R T Brum, E M Souza
PURPOSE: The aim of this study was to evaluate the effect of surface treatment and universal adhesive on the microshear bond strength of nanoparticle composite repairs. METHODS: One hundred and forty-four specimens were built with a nanofilled composite (Filtek Supreme Ultra, 3M ESPE). The surfaces of all the specimens were polished with SiC paper and stored in distilled water at 37°C for 14 days. Half of the specimens were then air abraded with Al2O3 particles and cleaned with phosphoric acid...
April 12, 2017: Operative Dentistry
https://www.readbyqxmd.com/read/28388273/musculoskeletal-imaging-findings-of-hematologic-malignancies
#15
Shannon M Navarro, George R Matcuk, Dakshesh B Patel, Matthew Skalski, Eric A White, Anderanik Tomasian, Aaron J Schein
Hematologic malignancies comprise a set of prevalent yet clinically diverse diseases that can affect every organ system. Because blood components originate in bone marrow, it is no surprise that bone marrow is a common location for both primary and metastatic hematologic neoplasms. Findings of hematologic malignancy can be seen with most imaging modalities including radiography, computed tomography (CT), technetium 99m ((99m)Tc) methylene diphosphonate (MDP) bone scanning, fluorine 18 ((18)F) fluorodeoxyglucose (FDG) positron emission tomography (PET)/CT, and magnetic resonance (MR) imaging...
May 2017: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/28378046/-microendoscopic-minimally-invasive-techniques-in-lacrimal-surgery
#16
K-H Emmerich, S Amin, H-W Meyer-Rüsenberg, R Ungerechts
BACKGROUND: Lacrimation of the eye is a relatively common problem, the cause of which must be clarified by differential diagnostics. The most important symptom of a dysfunction of lacrimal drainage is epiphora. METHODS: Due to the enhancement and miniaturization of endoscopes, which were originally used in gastroduodenoscopy in the 1990s, it is possible to check the anatomical structure and visualize pathological changes of the lacrimal drainage system, which is only approximately 1 mm in diameter...
May 2017: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/28367893/effect-of-the-type-of-acidic-monomer-on-the-bond-durability-of-two-bottle-type-ceramic-primer
#17
Hideki Tanimura
Ceramic primers consisting of γ-methacryloxypropyl trimethoxysilane (γ-MPS) and either 4-methacryloyloxyethyl trimellitate (4-MET) or 10-methacryloyloxydecyl dihydrogen phosphate (MDP) are useful for facilitating bonding of resin cement to silica-based ceramic surfaces. However, bond stability at the resin-ceramic interface differs among commercial ceramic primers. To determine the ability of 4-MET or MDP to hydrolyze the methoxy group in γ-MPS, the author designed two-bottle experimental ceramic primers comprising γ-MPS solution and an activator solution of 4-MET or MDP...
2017: Journal of Oral Science
https://www.readbyqxmd.com/read/28365256/corrigendum-to-epicutaneous-immunization-with-protein-antigen-tnp-ig-and-nod2-ligand-muramyl-dipeptide-mdp-reverses-skin-induced-suppression-of-contact-hypersensitivity-pharmacol-rep-66-2014-137-142
#18
Monika Majewska-Szczepanik, Iwona Dorożyńska, Anna Strzępa, Marian Szczepanik
No abstract text is available yet for this article.
June 2017: Pharmacological Reports: PR
https://www.readbyqxmd.com/read/28358121/chemical-interaction-mechanism-of-10-mdp-with-zirconia
#19
Noriyuki Nagaoka, Kumiko Yoshihara, Victor Pinheiro Feitosa, Yoshiyuki Tamada, Masao Irie, Yasuhiro Yoshida, Bart Van Meerbeek, Satoshi Hayakawa
Currently, the functional monomer 10-methacryloyloxy-decyl-dihydrogen-phosphate (10-MDP) was documented to chemically bond to zirconia ceramics. However, little research has been conducted to unravel the underlying mechanisms. This study aimed to assess the chemical interaction and to demonstrate the mechanisms of coordination between 10-MDP and zirconium oxide using (1)H and (31)P magic angle spinning (MAS) nuclear magnetic resonance (NMR) and two dimensional (2D) (1)H → (31)P heteronuclear correlation (HETCOR) NMR...
March 30, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28350843/high-hiv-prevalence-and-incidence-among-women-in-southern-mozambique-evidence-from-the-mdp-microbicide-feasibility-study
#20
Sibone Mocumbi, Mitzy Gafos, Khatia Munguambe, Ruth Goodall, Sheena McCormack
BACKGROUND: The study aimed to assess the feasibility of conducting large scale HIV prevention clinical trials in Mozambique by measuring HIV prevalence and incidence among women of reproductive age. This paper describes the baseline socio-demographic characteristics of the Mozambique Microbicides Development Programme (MDP) feasibility cohort, baseline prevalence of HIV and other STIs, and HIV incidence. METHODS: The Mozambique MDP feasibility study was conducted from September 2007 to August 2009 in urban Mavalane and rural Manhiça, in Southern Mozambique...
2017: PloS One
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