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https://www.readbyqxmd.com/read/29242433/a-new-species-of-i-paraleptophlebia-i-lestage-1917-ephemeroptera-%C3%A2-leptophlebiidae-and-a-re-description-of-adults-for-i-paraleptophlebia-i-i-westoni-i-imanishi-1937-with-the-first-description-of-the-larva-from-the-russian-far-east
#1
Tatiana M Tiunova
Male, female imagoes and eggs of Paraleptophlebia kunashirica sp. nov. and the larva, male and female imagoes of Paraleptophlebia westoni are described based on material from the Russian Far East. Comparison of the male imago of Paraleptophlebia kunashirica sp. nov. and the larva and male imago of Paraleptophlebia westoni with other known larvae and imagoes of Paraleptophlebia are given. Paraleptophlebia westoni larvae may be distinguished from congeners by characters associated with the mouthparts, such as the ratio of the length of the maxillary and labial palp segments, shape of hypopharynx, and structure of the claw...
October 17, 2017: Zootaxa
https://www.readbyqxmd.com/read/29229323/mri-based-assessment-of-3d-intrafractional-motion-of-head-and-neck-cancer-for-radiation%C3%A2-therapy
#2
Oliver J Gurney-Champion, Dualta McQuaid, Alex Dunlop, Kee H Wong, Liam C Welsh, Angela M Riddell, Dow-Mu Koh, Uwe Oelfke, Martin O Leach, Christopher M Nutting, Shreerang A Bhide, Kevin J Harrington, Rafal Panek, Kate L Newbold
PURPOSE: To determine the 3-dimensional (3D) intrafractional motion of head and neck squamous cell carcinoma (HNSCC). METHODS AND MATERIALS: Dynamic contrast-enhanced magnetic resonance images from 56 patients with HNSCC in the treatment position were analyzed. Dynamic contrast-enhanced magnetic resonance imaging consisted of 3D images acquired every 2.9 seconds for 4 minutes 50 seconds. Intrafractional tumor motion was studied in the 3 minutes 43 seconds of images obtained after initial contrast enhancement...
October 16, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/29228752/nonsteroidal-anti-inflammatory-drugs-using-and-risk-of-head-and-neck-cancer-a-dose-response-meta-analysis-of-prospective-cohort-studies
#3
Jun Shi, Weidong Leng, Lunhua Zhao, Chenli Xu, Jue Wang, Xiaoli Chen, Yu Wang, Xingchun Peng
Conflicting results identifying the relationship between nonsteroidal anti-inflammatory drugs using and head and neck cancer risk. Therefore, we performed this meta-analysis to clarify and quantitative assessed the relationship between nonsteroidal anti-inflammatory drugs using and head and neck cancer risk. Up to March 2017, 11 original publications were included in this meta-analysis. Our results showed statistically significant association between nonsteroidal anti-inflammatory drugs using and head and neck cancer risk reduction...
November 17, 2017: Oncotarget
https://www.readbyqxmd.com/read/29199656/retrospective-analysis-of-palliative-metronomic-chemotherapy-in-head-and-neck-cancer
#4
V M Patil, V Noronha, A Joshi, L Nayak, N Pande, A Chandrashekharan, S Dhumal, A Bhattacharjee, S Banavali, K Prabhash
BACKGROUND: Metronomic chemotherapy has shown promising results in selected patients of head and neck cancer in a small randomized study. This retrospective analysis was done to see whether the efficacy of metronomic chemotherapy in an unselected cohort of head and neck cancer patients is similar to that reported in the randomized study and the influence of the site and subsite of head and neck cancer on survival. MATERIALS AND METHODS: This was a retrospective analysis of head and neck cancer patients who received palliative metronomic chemotherapy between January 2013 and February 2015...
January 2017: Indian Journal of Cancer
https://www.readbyqxmd.com/read/29192305/association-of-quantitative-metastatic-lymph-node-burden-with-survival-in-hypopharyngeal-and-laryngeal-cancer
#5
Allen S Ho, Sungjin Kim, Mourad Tighiouart, Cynthia Gudino, Alain Mita, Kevin S Scher, Anna Laury, Ravi Prasad, Stephen L Shiao, Nabilah Ali, Chrysanta Patio, Jon Mallen-St Clair, Jennifer E Van Eyk, Zachary S Zumsteg
Importance: Nodal staging for laryngohypopharyngeal cancers is based primarily on size and laterality, with less value placed on absolute number of metastatic lymph nodes (LNs). We are aware of no studies to date that have specifically addressed the prognostic effect of quantitative nodal burden in larynx or hypopharynx malignancies. Objective: To assess the independent impact of quantitative metastatic LN burden on mortality risk. Design, Setting, and Participants: Univariate and multivariable models were constructed to evaluate the association between patients' number of metastatic LNs and their survival, adjusting for factors such as nodal size, laterality, extranodal extension, margin status, and adjuvant treatment...
November 30, 2017: JAMA Oncology
https://www.readbyqxmd.com/read/29192300/characterizing-an-ultra-high-risk-subset-of-patients-with-hypopharynx-and-larynx-cancer-the-power-of-lymph-node-burden
#6
Ryan K Orosco, Ezra E Cohen
No abstract text is available yet for this article.
November 30, 2017: JAMA Oncology
https://www.readbyqxmd.com/read/29187757/the-role-of-laryngectomy-in-locally-advanced-thyroid-carcinoma-review-of-16-cases
#7
A I Chala, S Vélez, A Sanabria
Locally advanced disease with larynx invasion is a challenge to the surgeon, but laryngectomy is almost never necessary in thyroid carcinoma. The aim of this study was to review the clinical outcomes of patients with locally advanced thyroid carcinoma invading the larynx who underwent laryngectomy. A case series of patients treated in a tertiary care hospital was reviewed. Data about the type of operation, method of reconstruction, complications and overall survival of 16 patients operated on between 2002 and 2015 with larynx invasion is presented...
November 30, 2017: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/29180076/delineation-of-the-primary-tumour-clinical-target-volumes-ctv-p-in-laryngeal-hypopharyngeal-oropharyngeal-and-oral-cavity-squamous-cell-carcinoma-airo-caca-dahanca-eortc-georcc-gortec-hknpcsg-hncig-iag-kht-lprhht-ncic-ctg-ncri-nrg-oncology-phns-sbrt-somera
#8
Vincent Grégoire, Mererid Evans, Quynh-Thu Le, Jean Bourhis, Volker Budach, Amy Chen, Abraham Eisbruch, Mei Feng, Jordi Giralt, Tejpal Gupta, Marc Hamoir, Juliana K Helito, Chaosu Hu, Keith Hunter, Jorgen Johansen, Johannes Kaanders, Sarbani Ghosh Laskar, Anne Lee, Philippe Maingon, Antti Mäkitie, Francesco Micciche', Piero Nicolai, Brian O'Sullivan, Adela Poitevin, Sandro Porceddu, Krzysztof Składowski, Silke Tribius, John Waldron, Joseph Wee, Min Yao, Sue S Yom, Frank Zimmermann, Cai Grau
PURPOSE: Few studies have reported large inter-observer variations in target volume selection and delineation in patients treated with radiotherapy for head and neck squamous cell carcinoma. Consensus guidelines have been published for the neck nodes (see Grégoire et al., 2003, 2014), but such recommendations are lacking for primary tumour delineation. For the latter, two main schools of thoughts are prevailing, one based on geometric expansion of the Gross Tumour Volume (GTV) as promoted by DAHANCA, and the other one based on anatomical expansion of the GTV using compartmentalization of head and neck anatomy...
November 24, 2017: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/29171929/ahns-series-do-you-know-your-guidelines-principles-of-treatment-for-locally-advanced-or-unresectable-head-and-neck-squamous-cell-carcinoma
#9
Cory D Fulcher, Missak Haigentz, Thomas J Ow
This article is a continuation of the "Do You Know Your Guidelines" series, initiated by the Education committee of the American Head and Neck Society. Treatment guidelines for advanced head and neck squamous cell carcinoma are reviewed here, including the critical roles of radiotherapy, chemotherapy, and the recent application of immunotherapy agents. We will be limiting this discussion to include cancers of the oral cavity, oropharynx, hypopharynx, and larynx. It should be noted that much of the article pertains to human papillomavirus (HPV)-negative oropharyngeal cancer where applicable, as HPV-positive oropharyngeal squamous cell carcinoma carries a different natural history, different prognosis, and now different staging criteria...
November 24, 2017: Head & Neck
https://www.readbyqxmd.com/read/29130568/flexible-next-generation-robotic-surgical-system-for-transoral-endoscopic-hypopharyngectomy-a-comparative-preclinical-study
#10
Ichiro Tateya, Yoon Woo Koh, Raymond K Tsang, Steven S Hong, Ryuji Uozumi, Yo Kishimoto, Taro Sugimoto, F Christopher Holsinger
BACKGROUND: The purpose of this cadaveric study was to determine the efficacy of a flexible, next-generation robotic surgical system for transoral robotic hypopharyngectomy. METHODS: A comparative evaluation study of the flexible versus rigid robotic surgical systems for the hypopharynx was conducted using 3 cadavers. Endpoints for assessment were visualization of the hypopharynx, access to the hypopharynx, and difficulty of dissection. Hypopharyngectomy was performed on 3 other cadavers using the da Vinci Sp surgical system...
November 11, 2017: Head & Neck
https://www.readbyqxmd.com/read/29126495/surgical-management-of-oral-cancer
#11
REVIEW
Rabie M Shanti, Bert W O'Malley
Today, most head and neck cancer subsites, such as the larynx, hypopharynx, nasopharynx, and oropharynx, are treated with radiation therapy with or without chemotherapy as a primary treatment modality. Surgery is reserved for the salvage of recurrent tumors that occur within the head and neck in the absence of distant (ie, lung, liver) metastasis. However, unlike all other head and neck subsites, oral cancer should ideally be managed with primary surgery with the possibility of adjuvant radiation therapy with or without chemotherapy depending on the presence of certain high-risk pathologic features...
January 2018: Dental Clinics of North America
https://www.readbyqxmd.com/read/29110221/transoral-robotic-surgery-for-oncocytic-ductal-cyst-of-hypopharynx-a-lesion-with-a-high-probability-of-recurrence
#12
Enrique Cadena, Alfredo Romero-Rojas, Ricardo Guerra, Carlos Pérez-Mitchell
Hypopharyngeal cysts are very uncommon pathology. They are presented in adult people over 60 years. Although oncocytic cysts are benign tumors, an incomplete resection causes recurrence. The symptoms are not specific, but the more frequent are dyspnea and foreign body sensation upon swallowing. Diagnosis usually is under general anesthesia during intubation. A flexible fiberoptic laryngoscopy could be insufficient; the trumpet maneuver during this examination can reveled occult cysts. To perform a total resection, the surgeon must have a complete exposition of the operative field...
November 6, 2017: Journal of Robotic Surgery
https://www.readbyqxmd.com/read/29106786/iatrogenic-perforation-of-hypopharynx-as-a-cause-of-severe-descending-necrotizing-mediastinitis-a-case-report
#13
(no author information available yet)
The authors present a case report of severe descending necrotizing mediastinitis (DNM) etiologically of unrecognized traumatic endotracheal intubation with hypopharynx-esophageal junction perforation. Patient was treated inadequately for seven days in local hospital what was the cause of sepsis progression into the septic shock with multiorgan dysfunction syndrome. Patient was transferred to specialized hospital and was immediately operated in general anaesthesia - combined transcervical approach and lateral thoracotomy was used for mediastinal drainage and debridement...
October 6, 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/29095310/sonography-used-in-the-infantile-desmoid-fibromatosis-of-postcricoid-area-a-case-report
#14
Chunxia Xia, Qiang Zhu, Changli Yue, Minxia Hu, Pingdong Li, Zheng Li
RATIONALE: Infantile desmoid fibromatosis of the postcricoid area is a rare disease and is characterized by a proliferation of fibrous tissue with non-metastasis, local infiltration, and a high rate of recurrence after surgical resection. Currently, ultrasound is scarcely used in the hypopharynx and larynx area. PATIENT CONCERNS: A 4-year-old boy presented with hoarseness, deep voice and snoring for 2∼4 years without any surgical history. On sonography, the lesion was found in the postcricoid area, and the left larynx showed impaired mobility in real time observation...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29080963/trends-in-treatment-incidence-and-survival-of-hypopharynx-cancer-a-20-year-population-based-study-in-the-netherlands
#15
Japke F Petersen, Adriana J Timmermans, Boukje A C van Dijk, Lucy I H Overbeek, Laura A Smit, Frans J M Hilgers, Martijn M Stuiver, Michiel W M van den Brekel
Hypopharynx cancer has the worst prognosis of all head and neck squamous cell cancers. Since the 1990s, a treatment shift has appeared from a total laryngectomy towards organ preservation therapies. Large randomized trials evaluating treatment strategies for hypopharynx cancer, however, remain scarce, and frequently this malignancy is evaluated together with larynx cancer. Therefore, our aim was to determine trends in incidence, treatment and survival of hypopharynx cancer. We performed a population-based cohort study including all patients diagnosed with T1-T4 hypopharynx cancer between 1991 and 2010 in the Netherlands...
October 28, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29075744/multidisciplinary-clinic-management-of-head-and-neck-cancer
#16
Melanie Townsend, Dorina Kallogjeri, Nicholas Scott-Wittenborn, Katherine Gerull, Stacy Jansen, Brian Nussenbaum
Importance: Contemporary management of head and neck cancer involves professionals from multiple specializations. Streamlined care that reduces delays yet allows for comprehensive evaluation is needed. Objective: To evaluate a single-day, single-appointment, multidisciplinary head and neck clinic model for reduction in treatment delay and comprehensiveness of care. Design, Setting, and Participants: A retrospective cohort analysis was conducted from June 1, 2015, to July 31, 2016, of outpatients at a single, academic medical center...
October 26, 2017: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/29069791/immunohistochemical-biomarkers-and-volumetric-parameters-for-predicting-radiotherapy-based-outcomes-in-patients-with-p16-negative-pharyngeal-cancer
#17
Rui-Yun Chen, Ying-Chun Lin, Shang-Wen Chen, Tze-Yi Lin, Te-Chun Hsieh, Kuo-Yang Yen, Ji-An Liang, Shih-Neng Yang, Yao-Ching Wang, Ya-Huey Chen, Shu-Fen Chiang, Chia-Hung Kao
BACKGROUND: This study determined the prognostic effects of immunohistochemical biomarkers and volumetric parameters predicting radiotherapy-based treatment in patients with p16-negative squamous cell carcinoma of the oropharynx or hypopharynx. RESULTS: VEGF immunoreactivity > 2 and GLUT1 overexpression were prognostic factors for lower cause-specific survival. Moreover, both factors were associated with lower disease-free survival. The predictors of lower primary relapse-free survival were VEGF immunoreactivity > 2 and CT-based gross tumor volume > 16 mL...
September 22, 2017: Oncotarget
https://www.readbyqxmd.com/read/29068974/an-atypical-lipomatous-tumor-mimicking-a-giant-fibrovascular-polyp-of-the-hypopharynx-a-case-report
#18
Khrystyna E Ioanidis, Stephanie Danielle MacNeil, Keng Yeow Tay, Bret Wehrli
RATIONALE: Giant fibrovascular polyps (GFVPs) found in the hypopharynx are exceedingly rare. These are benign tumors which are identified by CT or MRI and usually treated based on symptoms. Even more rarely, pathology may identify one of these masses as an atypical lipomatous tumor (ALT). This paper will present a case of an ALT of the hypopharynx that was originally classified as a GFVP, highlighting the difficulty in distinguishing between them and the importance of making the correct diagnosis...
October 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29067796/risk-factors-of-and-treatments-for-pharyngocutaneous-fistula-occurring-after-oropharynx-and-hypopharynx-reconstruction
#19
Su Bin Do, Chul Hoon Chung, Yong Joon Chang, Byeong Jun Kim, Young Soo Rho
BACKGROUND: A pharyngocutaneous fistula is a common and difficult-to-manage complication after head and neck reconstruction. It can lead to serious complications such as flap failure, carotid artery rupture, and pharyngeal stricture, and may require additional surgery. Previous radiotherapy, a low serum albumin level, and a higher T stage have been proposed as contributing factors. We aimed to clarify the risk factors for pharyngocutaneous fistula in patients who underwent flap reconstruction and to describe our experiences in treating pharyngocutaneous fistula...
November 2017: Archives of Plastic Surgery
https://www.readbyqxmd.com/read/29064308/systematic-review-of-drug-induced-sleep-endoscopy-scoring-systems
#20
Janine M Amos, Megan L Durr, Heather C Nardone, Cristina M Baldassari, Angela Duggins, Stacey L Ishman
Objective To systematically review the scoring systems used to report findings during drug-induced sleep endoscopy (DISE) for adults and children with obstructive sleep apnea. Data Sources PubMed, CINAHL, EBM Reviews, Embase, and Scopus databases. Review Methods This is a systematic review of all indexed years of publications referring to scoring of DISE for children and adults with obstructive sleep apnea. The type of DISE scoring system utilized was the primary outcome. PRISMA guidelines were followed to carry out this review; articles were independently reviewed by 2 investigators...
October 1, 2017: Otolaryngology—Head and Neck Surgery
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