keyword
https://read.qxmd.com/read/38507494/millimeter-scale-magnetic-implants-paired-with-a-fully-integrated-wearable-device-for-wireless-biophysical-and-biochemical-sensing
#21
JOURNAL ARTICLE
Ji Wan, Zhongyi Nie, Jie Xu, Zixuan Zhang, Shenglian Yao, Zehua Xiang, Xiang Lin, Yuxing Lu, Chen Xu, Pengcheng Zhao, Yiran Wang, Jingyan Zhang, Yaozheng Wang, Shaotong Zhang, Jinzhuo Wang, Weitao Man, Min Zhang, Mengdi Han
Implantable sensors can directly interface with various organs for precise evaluation of health status. However, extracting signals from such sensors mainly requires transcutaneous wires, integrated circuit chips, or cumbersome readout equipment, which increases the risks of infection, reduces biocompatibility, or limits portability. Here, we develop a set of millimeter-scale, chip-less, and battery-less magnetic implants paired with a fully integrated wearable device for measuring biophysical and biochemical signals...
March 22, 2024: Science Advances
https://read.qxmd.com/read/38507468/a-tough-bioadhesive-hydrogel-supports-sutureless-sealing-of-the-dural-membrane-in-porcine-and-ex-vivo-human-tissue
#22
JOURNAL ARTICLE
Kyle C Wu, Benjamin R Freedman, Phoebe S Kwon, Matthew Torre, Daniel O Kent, Wenya Linda Bi, David J Mooney
Complete sequestration of central nervous system tissue and cerebrospinal fluid by the dural membrane is fundamental to maintaining homeostasis and proper organ function, making reconstruction of this layer an essential step during neurosurgery. Primary closure of the dura by suture repair is the current standard, despite facing technical, microenvironmental, and anatomic challenges. Here, we apply a mechanically tough hydrogel paired with a bioadhesive for intraoperative sealing of the dural membrane in rodent, porcine, and human central nervous system tissue...
March 20, 2024: Science Translational Medicine
https://read.qxmd.com/read/38507150/pore-graded-borosilicate-bioactive-glass-scaffolds-in-vitro-dissolution-and-cytocompatibility
#23
JOURNAL ARTICLE
Agata Szczodra, Amel Houaoui, Turkka Salminen, Markus Hannula, Virginia Alessandra Gobbo, Sonya Ghanavati, Susanna Miettinen, Jonathan Massera
3D borosilicate bioactive glass (1393B20 and B12.5MgSr) scaffolds were prepared by robocasting, with and without a dense layer at the top. Pore graded scaffolds are promising as they allow for membrane deposition and could limit the risk of soft tissue infiltration. In vitro dissolution was studied in tris(hydroxymethyl)aminomethane (TRIS) and Simulated Body Fluid (SBF). 1393B20 scaffolds dissolved faster than B12.5MgSr in TRIS whereas they dissolved slower in SBF. The difference in dissolution profiles, as a function of the medium used, is assigned to the different rates of precipitation of hydroxyapatite (HA)...
March 20, 2024: Journal of Materials Science. Materials in Medicine
https://read.qxmd.com/read/38506991/measuring-size-and-number-concentration-of-metallic-nanoparticles-using-spicp-ms
#24
JOURNAL ARTICLE
Matthew Hansen, Jeffrey D Clogston
This protocol describes how to measure the size and concentration of individual metallic nanoparticles using inductively coupled plasma-mass spectrometry (ICP-MS) in single-particle (sp) mode. Accurately determining the size of individual nanoparticles on a per-particle basis, both quickly and accurately, is an ever-increasing need within nanoparticle characterization. ICP-MS is capable of measuring a broad range of metallic nanoparticle sizes with high resolution, thus allowing the measurement of multiple particle populations for the quality assessment of nanoformulations...
2024: Methods in Molecular Biology
https://read.qxmd.com/read/38506383/investigation-of-fatal-traumatic-head-injuries
#25
JOURNAL ARTICLE
Kerem Sehlikoğlu, Abdurrahim Türkoğlu, Turgay Bork, Muhammet Batbaş
BACKGROUND: Traumatic head injuries (THIs) are one of the major causes of death in forensic cases. The aim of this study was to investigate the characteristics of patients with fatal THIs. METHODS: In this study, a total of 311 patients with fatal THIs, who underwent postmortem examinations and/or autopsies, were retrospectively analyzed. Cases were evaluated based on sex, age group, incident origin, cause of the incident, presence of skull fracture, type of fractured bone (if any), fracture localization and pattern, presence and type of intracranial lesion (if any), and cause of death...
March 2024: Turkish Journal of Trauma & Emergency Surgery: TJTES
https://read.qxmd.com/read/38504684/an-exploratory-study-on-the-association-of-multiple-metals-in-serum-with-preeclampsia
#26
JOURNAL ARTICLE
Jie He, Yudong Pu, Yue Du, Haixia Liu, Xiaoxue Wang, Shuzhen He, Shiwei Ai, Yuhui Dang
BACKGROUND: Individual metal levels are potential risk factors for the development of preeclampsia (PE). However, understanding of relationship between multiple metals and PE remains elusive. PURPOSE: The purpose of this study was to explore whether eight metals [zinc (Zn), manganese (Mn), copper (Cu), nickel (Ni), lead (Pb), arsenic (As), cadmium (Cd), and mercury (Hg)] in serum had a certain relationship with PE. METHODS: A study was conducted in Dongguan, China...
2024: Frontiers in Public Health
https://read.qxmd.com/read/38503688/selective-recovery-of-battery-grade-li2co3-from-spent-ncm-cathode-materials-using-a-one-step-method-of-co2-carbonation-recovery-without-acids-or-bases
#27
JOURNAL ARTICLE
Wenjun Ma, Zhiyuan Liang, Xu Zhang, Yidi Liu, Qinxin Zhao
The recovery of spent lithium-ion batteries by traditional acid leaching is limited by serious pollution, complicated technology, and the low purity of Li2CO3. To address the problems of the traditional acid leaching process and increasing demand for decarbonization, a technique for the selective carbonation leaching of Li and the recovery of battery-grade Li2CO3 by a simple concentration precipitation process without acids or bases was developed. The coupling of CO2 and reducing agents could effectively promote the precipitation of MCO3 (M=Ni/Co/Mn) and the selective leaching of Li by decreasing the reducing capability needed for transition metals and decreasing the pH of the solution...
March 19, 2024: ChemSusChem
https://read.qxmd.com/read/38502219/the-increasing-burden-of-emergency-department-and-inpatient-consultations-for-papilledema
#28
JOURNAL ARTICLE
Hetal J Ray, Avital Lily Okrent Smolar, Michael Dattilo, Walid Bouthour, Gabriele Berman, Jason H Peragallo, Sachin Kedar, Andrew M Pendley, James G Greene, Matthew T Keadey, David W Wright, Beau B Bruce, Nancy J Newman, Valérie Biousse
BACKGROUND: Increasing incidence of idiopathic intracranial hypertension (IIH), overreported radiologic signs of intracranial hypertension, difficult access to outpatient neuro-ophthalmology services, poor insurance coverage, and medicolegal concerns have lowered the threshold for emergency department (ED) visits for "papilledema." Our objective was to examine referral patterns and outcomes of neuro-ophthalmology ED and inpatient consultations for concern for papilledema. METHODS: At one university-based quaternary care center, all adults referred for "papilledema" over one year underwent a standardized ED "papilledema protocol...
March 19, 2024: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
https://read.qxmd.com/read/38496110/comparison-of-opioid-based-versus-opioid-sparing-anesthesia-in-patients-undergoing-glioma-surgery
#29
JOURNAL ARTICLE
Anupama A S, Ashutosh Kaushal, Vaishali Waindeskar, Saurabh Saigal, Anuj Jain, Harish Kumar, Pranita Mandal, Sandeep Kumar, Sweta Kumari, Anjan K Sahoo
Background In the neurosurgical population, opioids may cause respiratory depression, leading to hypercapnia, increased cerebral blood flow (CBF), and ultimately increased intracranial pressure (ICP), which can mask early signs of intracranial complications and delayed emergence. This study was designed to compare perioperative hemodynamic stability, analgesia, and recovery parameters in opioid-based (fentanyl) general anesthesia versus opioid-sparing (dexmedetomidine) general anesthesia in patients undergoing glioma surgeries...
February 2024: Curēus
https://read.qxmd.com/read/38495962/cerebral-infarction-due-to-post-traumatic-cerebral-vasospasm-in-a-12-year-old-female
#30
Daisuke Tanikawa, Yushiro Take, Nobuaki Naito, Akio Teranishi, Hiroki Kurita
Cerebral infarction due to post-traumatic cerebral vasospasm is rare. Although some modalities are recommended to detect post-traumatic cerebral vasospasm, its diagnosis remains controversial and challenging. Therefore, in this report, we will use a case report to highlight challenges and to delineate the characteristics of post-traumatic cerebral vasospasm in pediatric patients, including the diagnostic and treatment options. A 12-year-old female was admitted to our hospital following a motor vehicle collision...
March 2024: Curēus
https://read.qxmd.com/read/38489923/trace-elements-in-bean-to-bar-chocolates-from-brazil-and-ecuador
#31
JOURNAL ARTICLE
Vitor Hugo Burgon, Manuela Luísa Nunes Silva, Raquel Fernanda Milani, Marcelo Antonio Morgano
BACKGROUND: The high quality and unique flavor and aroma of bean-to-bar chocolates have resulted in an increase in the consumption of these products. Nevertheless, cocoa beans may present inorganic contaminants from environmental and anthropogenic sources which can contribute to contamination of the chocolates, despite the fewer processing steps and few ingredients used in bean-to-bar manufacturing process compared to the industrial one. Therefore, this study aimed to evaluate the content of trace elements (As, Cd, Co, Cu, Hg, Pb, Se) in bean-to-bar chocolates and traceable cocoa beans from Brazil and Ecuador...
March 13, 2024: Journal of Trace Elements in Medicine and Biology
https://read.qxmd.com/read/38489820/neurocognitive-outcomes-and-associated-clinical-factors-5-years-after-surgery-in-children-with-craniosynostosis
#32
JOURNAL ARTICLE
Joo Whan Kim, Kyung Hyun Kim, Ji Hoon Phi, Ji Yeoun Lee, Eun Jung Koh, Byung Jun Kim, Jee Hyeok Chung, Min-Sup Shin, Seung-Ki Kim
OBJECTIVE: Craniosynostosis involves early closure of one or more sutures, which is known to limit normal cranium growth and interfere with normal brain development. Various surgical methods are used, ranging from minimally invasive strip craniectomy to more extensive whole-vault cranioplasty. This study aimed to evaluate neurocognitive outcomes 5 years after surgical treatment in children with craniosynostosis and to evaluate relevant clinical factors. METHODS: After exclusion of genetically confirmed syndromic craniosynostosis patients, a retrospective review was conducted on 112 nonsyndromic craniosynostosis patients who underwent surgical treatment and follow-up neurocognitive assessment...
March 15, 2024: Journal of Neurosurgery. Pediatrics
https://read.qxmd.com/read/38489080/three-dimensional-wall-thickness-distributions-of-unruptured-intracranial-aneurysms-characterized-by-micro-computed-tomography
#33
JOURNAL ARTICLE
Yasutaka Tobe, Takanobu Yagi, Koichi Kawamura, Kenta Suto, Yoichi Sawada, Yoshifumi Hayashi, Hirotaka Yoshida, Kazutoshi Nishitani, Yoshifumi Okada, Shigemi Kitahara, Mitsuo Umezu
Aneurysmal rupture is associated with wall thinning, but the mechanism is poorly understood. This study aimed to characterize the three-dimensional wall-thickness distributions of unruptured intracranial aneurysms. Five aneurysmal tissues were investigated using micro-computed tomography. First, the wall thickness was related to the aneurysmal wall appearances during surgery. The median wall thicknesses of the translucent and non-translucent walls were 50.56 and 155.93 µm, respectively (p < 0...
March 15, 2024: Biomechanics and Modeling in Mechanobiology
https://read.qxmd.com/read/38488947/dialysis-disequilibrium-syndrome-in-neurosurgery-literature-review-and-illustrative-case-example
#34
JOURNAL ARTICLE
Alexander R Evans, Xiaochun Zhao, Griffin L Ernst, Jorge Ortiz-Garcia, Ian F Dunn, John Burke
INTRODUCTION: The dialysis disequilibrium syndrome (DDS) is a complication in those undergoing dialysis for chronic kidney disease (CKD) or acute kidney injury (AKI), characterized by nonspecific symptoms that may progress to coma and death secondary to cerebral edema. This syndrome is associated with rapid change in electrolytes during dialysis with changes in intracranial pressure (ICP) and may have a higher incidence in the elderly neurosurgical patient population. METHODS: Literature review and illustrative case example...
March 15, 2024: GeroScience
https://read.qxmd.com/read/38488879/-67-zn-and-111-cd-labelled-green-manure-to-determine-the-fate-and-dynamics-of-zinc-and-cadmium-in-soil-fertilizer-crop-systems
#35
JOURNAL ARTICLE
Manja Künzli, Thilo Dürr-Auster, Christoph Bracher, Yang Zhao, Jill Bachelder, Frossard Emmanuel, Matthias Wiggenhauser
Isotope source tracing enables to accurately determine the fate of nutrients that are applied with fertilizers to soils. While this approach is well established for major nutrients such as nitrogen, it is not yet established for trace metals. Here, we aimed to determine the fate of the micronutrient zinc (Zn) and the contaminant cadmium (Cd) that were applied with an organic fertilizer to a soil-wheat system. A pot study was conducted in which wheat was grown on an alkaline soil. The soils received green manure and/or soluble Zn fertilizer and were compared with non-fertilized control treatments ( n  = 4 experimental replicates)...
March 15, 2024: Isotopes in Environmental and Health Studies
https://read.qxmd.com/read/38488878/the-prediction-of-estimated-cerebral-perfusion-pressure-with-trans-systolic-time-in-preterm-and-term-infants
#36
JOURNAL ARTICLE
Masashi Zuiki, Mikito Ohta, Naoe Fujita, Daisuke Uda, Madoka Uesugi, Akio Yamano, Eisuke Ichise, Hidechika Morimoto, Kanae Hashiguchi, Daisuke Kinoshita, Tatsuji Hasegawa, Tomoko Iehara
It is important to monitor cerebral perfusion in infants because hypo- and hyperperfusion can contribute to neurological injury. This study aimed to clarify the relationship between trans-systolic time (TST) and critical closing pressure (CrCP) or estimated cerebral perfusion pressure (CPPe) in neonates. Moreover, we aimed to determine the TST values in preterm and term infants with stable cerebral perfusion to clarify normative reference data. This multicentre prospective study included infants with arterial lines admitted to the neonatal intensive care units between December 2021 and August 2023...
March 15, 2024: European Journal of Pediatrics
https://read.qxmd.com/read/38488714/perfusion-techniques-for-an-800%C3%A2-g-premature-neonate-undergoing-arterial-switch-procedure-for-transposition-of-the-great-arteries%C3%A2
#37
Richard Owens, Madeline Loftin, Kellen Rosten, Douglas Fisher, Blake Denison, Erin Gottlieb, Charles Fraser
Early cardiac surgery in neonates and infants with congenital heart disease has been performed since the middle to late years of the twentieth century. To date, there are very few reports of successful congenital heart surgery using cardiopulmonary bypass (CPB) in premature babies less than 1000 g with serious congenital heart disease. Limited information is available in the literature describing perfusion techniques for this extremely fragile patient population. Miniaturization of the CPB circuit contributes to multiple factors that affect this population significantly...
March 2024: Journal of Extra-corporeal Technology
https://read.qxmd.com/read/38487358/the-impact-of-valsalva-manoeuvres-and-exercise-on-intracranial-pressure-and-cerebrovascular-dynamics-in-idiopathic-intracranial-hypertension
#38
JOURNAL ARTICLE
Andreas Yiangou, Samuel R C Weaver, Mark Thaller, James L Mitchell, Hannah S Lyons, Georgios Tsermoulas, Susan P Mollan, Samuel J E Lucas, Alexandra J Sinclair
Idiopathic intracranial hypertension (IIH) is a disease characterised by elevated intracranial pressure (ICP). The impact of straining and exercise on ICP regulation is poorly understood yet clinically relevant to IIH patient care. We sought to investigate the impact of Valsalva manoeuvres (VMs) and exercise on ICP and cerebrovascular haemodynamics in IIH. People with IIH were prospectively enrolled and had an intraparenchymal telemetric ICP sensor inserted. Three participants (age [mean ± standard deviation]: 40...
2024: Neuro-ophthalmology
https://read.qxmd.com/read/38483704/distribution-of-nitrate-nitrite-and-toxic-metals-in-the-soil-potato-system-and-its-health-risk-assessment-in-iran
#39
JOURNAL ARTICLE
Milad Zeinali, Ali Heshmati, Younes Mohammadi, Maryam Nili Ahmadabadi, Amir Nili-Ahmadabadi
Potato is one of the essential food products whose health quality is greatly influenced by soil contamination and properties. In the current study, we have investigated the physicochemical characteristics of agricultural areas and the accumulation of nitrite/nitrate and metals in potato products in Hamedan, Iran. After determining the physicochemical characteristics of soil samples from four agricultural regions of Hamedan, 48 potato samples were collected from these regions. The heavy metals and nitrate/nitrite content were determined by ICP-OES and calorimetric methods, respectively...
March 14, 2024: Environmental Geochemistry and Health
https://read.qxmd.com/read/38482467/rheoencephalography-a-non-invasive-method-for-neuromonitoring
#40
JOURNAL ARTICLE
Sandor Szabo, Zsolt Totka, Jozsef Nagy-Bozsoky, Istvan Pinter, Mihaly Bagany, Michael Bodo
In neurocritical care, the gold standard method is intracranial pressure (ICP) monitoring for the patient's lifesaving. Since it is an invasive method, it is desirable to use an alternative, noninvasive technique. The computerized real-time invasive cerebral blood flow (CBF) autoregulation (AR) monitoring calculates the status of CBF AR, called the pressure reactivity index (PRx). Studies documented that the electrical impedance of the head (Rheoencephalography - REG) can detect the status of CBF AR (REGx) and ICP noninvasively...
January 2024: Journal of electrical bioimpedance
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