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https://www.readbyqxmd.com/read/28440265/role-of-jun-amino-terminal-kinase-jnk-in-apoptosis-of-cavernosal-tissue-during-acute-phase-after-cavernosal-nerve-injury
#1
Won Hoon Song, Hwancheol Son, Soo Woong Kim, Jae-Seung Paick, Min Chul Cho
The present study aimed to identify which mitogen-activated protein kinase (p38 or Jun amino-terminal kinase [JNK]) was involved in cavernosal apoptosis during the acute phase after cavernosal nerve crush injury (CNCI) in rats to ameliorate apoptosis of cavernosal tissue, such as smooth muscle (SM). A total of twenty 10-week-old male Sprague-Dawley rats were divided equally into two groups: sham surgery (S) and CNCI (I). The I group approximated the clinical situation of men undergoing radical prostatectomy using two 60-second compressions of both CNs with a microsurgical vascular clamp...
April 18, 2017: Asian Journal of Andrology
https://www.readbyqxmd.com/read/28437442/relationship-between-early-onset-severe-intrahepatic-cholestasis-of-pregnancy-and-higher-risk-of-meconium-stained-fluid
#2
Maria C Estiú, Maria A Frailuna, Carla Otero, Marcela Dericco, Catherine Williamson, Jose J G Marin, Rocio I R Macias
BACKGROUND: Intrahepatic cholestasis of pregnancy (ICP) is the commonest gestational liver disease. The risk of adverse fetal outcome has been associated with the severity of maternal hypercholanemia after diagnosis. OBJECTIVE: To investigate whether there is a relationship between the severity and timing of onset of hypercholanemia and the risk of meconium-stained amniotic fluid (MSAF) and adverse neonatal events. STUDY DESIGN: The study included 382 pregnancies complicated by ICP managed at a referral hospital in Buenos Aires (Argentina) between June 2009 and December 2013...
2017: PloS One
https://www.readbyqxmd.com/read/28436607/visual-complaints-in-intracranial-germinomas
#3
Didier Frappaz, Claire Pedone, Philippe Thiesse, Alexandru Szathmari, Cécile Faure Conter, Carmine Mottolese, Christian Carrie
OBJECTIVE: Patients with brain tumors often report having visual complaints. This may be due to increased intracranial pressure, compression/invasion of the optic pathway or diplopia. We assessed the incidence and the etiology of visual symptoms in patients with intracranial germinoma tumors (ICGTs). METHODS AND MATERIALS: We performed a blinded retrospective review of the clinical charts and the initial magnetic resonance imaging (MRI) of 28 patients with ICGT...
April 24, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28436146/improving-zinc-accumulation-in-barley-endosperm-using-hvmtp1-a-transition-metal-transporter
#4
Paloma Menguer, Thomas Vincent, Anthony J Miller, James K M Brown, Eva Vincze, Søren Borg, Preben Bach Holm, Dale Sanders, Dorina Podar
Zinc (Zn) is essential for all life forms, including humans. It is estimated that around two billion people are deficient in their Zn intake. Human dietary Zn intake relies heavily on plants, which in many developing countries consists mainly of cereals. The inner part of cereal grain, the endosperm, is the part that is eaten after milling but contains only a quarter of the total grain Zn. Here we present results demonstrating that endosperm Zn content can be enhanced through expression of a transporter responsible for vacuolar Zn accumulation in cereals...
April 24, 2017: Plant Biotechnology Journal
https://www.readbyqxmd.com/read/28435179/real-time-measurement-of-size-resolved-elemental-composition-ratio-for-flame-synthesized-composite-nanoparticle-aggregates-using-a-tandem-smps-icp-oes
#5
Nathan Reed, Jiaxi Fang, Sanmathi Chavalmane, Pratim Biswas
Composite nanoparticles find application in catalysis, drug delivery, and energy storage and require increasingly fine control of their physical properties and composition. While composite nanoparticles have been widely synthesized and characterized, little work has systematically correlated the initial concentration of precursors and the final composition of flame synthesized composite nanoparticles. This relationship is explored in a diffusion flame aerosol reactor by coupling a scanning mobility particle sizer (SMPS) with an inductively coupled plasma optical emission spectrometer (ICP-OES)...
2017: Aerosol Science and Technology: the Journal of the American Association for Aerosol Research
https://www.readbyqxmd.com/read/28432507/study-of-the-potential-of-barnyard-grass-for-the-remediation-of-cd-and-pb-contaminated-soil
#6
Jianling Xu, Qiongyao Cai, Hanxi Wang, Xuejun Liu, Jing Lv, Difu Yao, Yue Lu, Wei Li, Yuanyuan Liu
In this study, the microwave digestion method was used to determine total cadmium (Cd) and lead (Pb) concentrations, the BCR method was used to determine different states of Cd and Pb, and atomic absorption spectroscopy (AAS) and inductively coupled plasma optical emission spectrometry (ICP-OES) were used to determine Cd and Pb concentrations in simulated soil and barnyard grass before and after planting barnyard grass to provide a theoretical basis for the remediation of Cd- and Pb-contaminated soil. The results showed that the bioconcentration factor changes with different Cd concentrations are relatively complex and that the removal rate increases regularly...
May 2017: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/28431870/the-effect-of-hypertonic-saline-and-mannitol-on-coagulation-in-moderate-traumatic-brain-injury-patients
#7
Haifeng Wang, Hongshi Cao, Xiaohong Zhang, Liang Ge, Li Bie
BACKGROUND: Hyperosmolar therapy, using either hypertonic saline (HTS) or mannitol (MT), is considered the treatment of choice for intracranial hypertension, a disorder characterized by high intracranial pressure (ICP). However, hyperosmolar agents have been postulated to impair coagulation and platelet function. The aim of this study was to identify whether HTS and MT could affect coagulation in moderate traumatic brain injury (TBI) patients. METHODS: In this prospective and randomized double-blind study, we included adult patients with moderate TBI...
April 14, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28430554/role-of-cerebrospinal-fluid-in-spaceflight-induced-ocular-changes-and-visual-impairment-in-astronauts
#8
Noam Alperin, Ahmet M Bagci, Carlos J Oliu, Sang H Lee, Byron L Lam
Purpose To determine the respective roles of vascular and cerebrospinal fluids in spaceflight-induced vision impairment in astronauts, known as the visual impairment and intracranial pressure (VIIP) syndrome. Materials and Methods This retrospective study was approved by the National Aeronautics and Space Administration institutional review board and is HIPAA compliant. All subjects provided written informed consent. Magnetic resonance (MR) imaging data from nine astronauts (mean age, 46.9 years) who flew on the space shuttle (14...
April 21, 2017: Radiology
https://www.readbyqxmd.com/read/28429903/causes-of-interruptions-in-postoperative-enteral-nutrition-in-children-with-congenital-heart-disease
#9
Jirong Qi, Zhuo Li, Yueshuang Cun, Xiaonan Li
BACKGROUND AND OBJECTIVES: Perioperative nutritional support has become a hot topic in the clinical management of congenital heart disease (CHD). Postoperative enteral nutrition (EN) offers many benefits, such as protection of the intestinal mucosa, reduced risk of infection, and low clinical costs. Interruptions in EN frequently influence nutritional support and clinical outcomes. We, therefore, aimed to determine the causes of interruptions in postoperative EN in CHD patients and discuss clinical counter measures...
May 2017: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28427977/decompressive-craniectomy-in-spontaneous-intracerebral-hemorrhage-a-case-control-study
#10
Yu Tung Lo, Angela An Qi See, Nicolas Kon Kam King
BACKGROUND: Decompressive craniectomy is performed to relieve intracranial pressure as an emergency procedure. There is no large study to systematically evaluate the benefit of decompressive craniectomy versus best medical therapy. This study evaluates the survival and long-term functional outcomes of decompressive craniectomy for spontaneous intracranial hemorrhage. METHODS: A total of 54 eligible patients with spontaneous supratentorial hemorrhage (median age 55, IQR 47-64) who underwent decompressive craniectomy were retrospectively matched to 72 patients managed with best medical treatment (median age 58, IQR 32-74)...
April 17, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28425250/retrospective-analysis-of-maternal-fetal-and-neonatal-outcomesof-intrahepatic-cholestasis-of-pregnancy-at-gazi-university
#11
Berrin Günaydin, Merih Bayram, Melis Altuğ, Semra Cevher, Nuray Bozkurt
BACKGROUND/AIM: Maternal, fetal, and neonatal outcomes in parturients with intrahepatic cholestasis of pregnancy (ICP) have been retrospectively documented. We aimed to present pregnancy outcomes of parturients with ICP who underwent delivery. The study was conducted during a 1-year period. MATERIALS AND METHODS: After ethics committee approval, data from 1 January to 31 December 2015 were collected to identify parturients with ICP. RESULTS: Ten out of 37 patients underwent normal spontaneous vaginal delivery (NSVD), and the remaining 27 parturients underwent cesarean section (CS)...
April 18, 2017: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/28423108/-potential-health-risks-from-consumption-of-water-with-arsenic-in-colima-mexico
#12
Oliver Mendoza-Cano, Ramón Alberto Sánchez-Piña, Julián Barrón-Quintana, Herguin Benjamin Cuevas-Arellano, Pilar Escalante-Minakata, Ramón Solano-Barajas
Objective: To estimate potential health risks due to chronic ingestion of arsenic from groundwater in Colima, Mexico. Materials and methods: Samples were randomly taken in 36 wells from 10 local aquifers. Analysis was performed by ICP-OES following international standards. Geostatistical interpolation was performed with ArcGIS, implementing a model weighting inverse distance to estimate arsenic routes of exposure and consumption on each locality. The Hazard Quotient Ratio (HQ) and carcinogenic risk (R) for As were estimated...
January 2017: Salud Pública de México
https://www.readbyqxmd.com/read/28421189/optic-nerve-sheath-diameter-ultrasound-evaluation-in-intensive-care-unit-possible-role-and-clinical-aspects-in-neurological-critical-patients-daily-monitoring
#13
M Toscano, G Spadetta, P Pulitano, M Rocco, V Di Piero, O Mecarelli, E Vicenzini
Background. The increase of the optic nerve sheath diameter (ONSD) is a reliable, noninvasive sonographic marker of intracranial hypertension. Aim of the study was to demonstrate the efficacy of ONSD evaluation, when monitoring neurocritical patients, to early identify malignant intracranial hypertension in patients with brain death (BD). Methods. Data from ultrasound ONSD evaluation have been retrospectively analyzed in 21 sedated critical patients with neurological diseases who, during their clinical course, developed BD...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28419063/the-effect-of-elevated-intracranial-pressure-on-frequency-tuning-of-air-conducted-ocular-vestibular-myogenic-potentials-in-m%C3%A3-ni%C3%A3-re-s-disease-patients
#14
Rebecca Maxwell, Claudia Jerin, Robert Gürkov
OBJECTIVE: To investigate the effect of increased intracranial pressure on ocular vestibular-evoked myogenic potential (oVEMP) amplitudes and frequency tuning in patients with Ménière's disease (MD) to elucidate whether oVEMPS recorded under such conditions could provide a simple and accurate diagnostic test for MD. SETTING: Tertiary referral center for otology and neurotology. PATIENTS: Ten patients with certain unilateral MD (mean age = 48...
April 17, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28419017/the-evaluation-of-trauma-care-the-comparison-of-2-high-level-pediatric-emergency-departments-in-the-united-states-and-turkey
#15
Alkan Bal, Michael Cooper, Amanda Lee, Murat Anil, Halim Hennes
OBJECTIVE: The purpose of the study is to compare the outcomes of pediatric trauma patients with motor vehicle crashes (MVCs) and motor vehicle versus pedestrian crashes (MPCs) at a level 1 pediatric trauma center in the United States and a pediatric trauma center in Turkey. METHODS: The medical records of all pediatric MVC and MPC subjects presenting to the emergency departments (EDs) of a level 3 hospital in Turkey (Izmir Tepecik Training and Research Hospital [ITTRH]) and a level 1 pediatric trauma center in the United States (Children's Medical Center Dallas [CMCD]) over a 1-year period were reviewed...
April 18, 2017: Pediatric Emergency Care
https://www.readbyqxmd.com/read/28419015/an-unanticipated-complication-of-atopic-dermatitis
#16
Megan E MacGillivray, Loretta Fiorillo
An infant with a history of atopic dermatitis presented to the emergency department on 5 occasions with flulike symptoms. Eventually, this child presented with signs of infection and increased intracranial pressure: fever, bulging anterior fontanel, and leukocytosis. A computed tomography scan identified a large frontal lobe brain abscess. The abscess was surgically drained; culture was positive for Staphylococcus aureus. The initial source of the infected brain abscess was explored. Ultimately, it was thought to be secondary to impetiginized atopic dermatitis, an unusual but serious consequence of a common skin condition...
April 18, 2017: Pediatric Emergency Care
https://www.readbyqxmd.com/read/28418431/body-burdens-sources-and-interrelations-of-selected-toxic-and-essential-elements-among-the-nine-cree-first-nations-of-eeyou-istchee-james-bay-region-of-northern-quebec-canada
#17
Evert Nieboer, Ian D Martin, Eric N Liberda, Eric Dewailly, Elizabeth Robinson, Leonard J S Tsuji
BACKGROUND: this article constitutes a report on the comprehensive Nituuchischaayihtitaau Aschii multi-community environment-and-health study conducted among the Cree peoples (Eeyouch) of northern Quebec, Canada. OBJECTIVES: to interpret observed concentrations of a suite of chemical elements in a multi-media biological monitoring study in terms of sources and predictors. METHODS: the concentrations of 5 essential and 6 toxic chemical elements were measured in whole blood, and/or in urine or hair by ICP-MS...
April 18, 2017: Environmental Science. Processes & Impacts
https://www.readbyqxmd.com/read/28417833/jugular-and-portal-vein-volume-middle-cerebral-vein-velocity-and-intracranial-pressure-in-dry-immersion
#18
Philippe Arbeille, Paul Avan, Loïc Treffel, Kathryn Zuj, Herve Normand, Pierre Denise
BACKGROUND: The objective was to determine if short term exposure to dry immersion (DI) results in a cephalic fluid shift similar to what has been observed with spaceflight. METHODS: Data were collected from 10 individuals at rest and during the first 2 h of dry immersion. Jugular vein (JV), portal vein (PV), and thyroid volume were measured using 3D echography. Middle cerebral vein velocity (MCVv) was determined using transcranial Doppler ultrasound. The cochlear response to audio stimulation was used to derive an estimate of intracranial pressure (dICP)...
May 1, 2017: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/28417342/adipose-tissue-derived-stem-cell-therapy-for-erectile-dysfunction-in-rats-a-systematic-review-and-meta-analysis
#19
REVIEW
Quan-Liang Hou, Meng-Ying Ge, Cheng-da Zhang, Dan-Dan Tian, Lian-Ke Wang, Hui-Zi Tian, Wen-Hua Wang, Wei-Dong Zhang
OBJECTIVE: We aimed to systematically assess the effect of adipose tissue-derived stem cell (ADSC) therapy and its influential factors on the treatment of erectile dysfunction (ED) in rats. METHODS: Two authors independently searched for published studies through PubMed and EMBASE from study inception until August 31, 2016. A meta-analysis was used to combine the effect estimate from the published studies. A subgroup analysis was performed to identify the effect of some influential factors...
April 17, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28415449/complementary-approaches-for-the-evaluation-of-biocompatibility-of-90-y-labeled-superparamagnetic-citric-acid-fe-er-3o4-coated-nanoparticles
#20
Bratislav Antic, Marko Boskovic, Jasmina Nikodinovic-Runic, Yue Ming, Hongguo Zhang, Emil S Bozin, Drina Janković, Vojislav Spasojevic, Sanja Vranjes-Djuric
Magnetic nanoparticles (MNPs) are of immense interest for diagnostic and therapeutic applications in medicine. Design and development of new iron oxide-based MNPs for such applications is of rather limited breadth without reliable and sensitive methods to determine their levels in body tissues. Commonly used methods, such as ICP, are quite problematic, due to the inability to decipher the origin of the detected iron, i.e. whether it originates from the MNPs or endogenous from tissues and bodily fluids. One of the approaches to overcome this problem and to increase reliability of tracing MNPs is to partially substitute iron ions in the MNPs with Er...
June 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
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