Pascale Ondoa, Andrea A Kim, T Sonia Boender, Guoqing Zhang, Stefanie Kroeze, Jeffrey Wiener, Tobias F Rinke de Wit, John Nkengasong
BACKGROUND: poor access to HIV viral load (VL) testing prevents the timely monitoring of HIV treatment adherence and efficacy. Factors enabling clinical benefits of VL testing when added to local standards of care, can inform the development of more cost-effective routine VL scale-up plans. We compared antiretroviral therapy (ART) switch practices in 13 clinics across six countries, with full (N=8), phasing-in (N=3) or no onsite access (N=2) to VL. METHODS: The analysis used data from the Pan-African Studies to Evaluate Resistance (PASER), observing virological and drug resistance outcomes among adults receiving first-or second-line ART between 2008 and 2015...
July 29, 2020: AIDS Research and Human Retroviruses