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https://www.readbyqxmd.com/read/29783012/decisional-conflict-among-patients-considering-treatment-options-for-lumbar-herniated-disc
#1
Hwang Richard, Lambrechts Sylvia, Liu Hui, Christopher S Saigal, Kwan Lorna, Cisneros Crystal, Langston T Holly, Duru O Kenrik
BACKGROUND: Lumbar herniated disc is a "preference-sensitive" condition, in which the optimal treatment choice is crucially dependent on an informed patient's goals and values. Little is known about decisional conflict, defined as an individual's level of uncertainty regarding a decision, in patients considering treatment for lumbar herniated discs. Our work aims to identify factors associated with decisional conflict and areas for improved shared decision-making. METHODS: We prospectively surveyed patients seeking treatment for a lumbar herniated disc at L4-L5 and/or L5-S1 with a physician at the UCLA Spine Center...
May 18, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29779478/exosomes-in-therapy-engineering-pharmacokinetic-and-future-applications
#2
Claudia Arenaccio, Chiara Chiozzini, Flavia Ferrantelli, Patrizia Leone, Eleonora Olivetta, Maurizio Federico
BACKGROUND: Eukaryotic cells release vesicles of different sizes under both physiological and pathological conditions. On the basis of the respective biogenesis, extracellular vesicles are classified as apoptotic bodies, microvesicles, and exosomes. Among these, exosomes are considered tools for innovative therapeutic interventions, especially when engineered with effector molecules. The delivery functions of exosomes are favored by a number of typical features. These include their small size (i...
May 20, 2018: Current Drug Targets
https://www.readbyqxmd.com/read/29776476/institute-of-medicine-early-infant-feeding-recommendations-for-childhood-obesity-prevention-implementation-by-immigrant-mothers-from-central-america
#3
Kathleen F Gaffney, Albert V Brito, Panagiota Kitsantas, Deborah A Kermer, Graciela Pereddo, Katya M Ramos
PURPOSES: Describe implementation of Institute of Medicine (IOM) early infant feeding recommendations for child obesity prevention by immigrant mothers from Central America; examine potential relationships with food insecurity and postpartum depressive symptoms. DESIGN AND METHODS: Using a cross-sectional, descriptive design, face-to-face interviews were conducted with 318 mothers of 2month old infants at a large pediatric setting for low income families. Logistic regression models assessed feeding practices, food insecurity and postpartum depressive symptoms...
May 2018: Journal of Pediatric Nursing
https://www.readbyqxmd.com/read/29769122/delay-on-first-antenatal-care-visit-and-its-associated-factors-among-pregnant-women-in-public-health-facilities-of-debre-markos-town-north-west-ethiopia
#4
Atsede Alle Ewunetie, Alemtsehay Mekonnen Munea, Belsity Temesgen Meselu, Muluye Molla Simeneh, Bekele Tesfaye Meteku
BACKGROUND: Delay on timely initiation of antenatal care has a great impact on adverse pregnancy out comes. However, evidences in Ethiopia revealed that majority of pregnant mothers did not start their first visit as recommrnded by WHO. The aim of this study was to assess delay and associated factors of first antenatal care visit among pregnant mothers at public health facilities of Debremarkos town, North West Ethiopia. METHODS: An institutional based crosss-sectional study was conducted from February to March, 2014 in public health facilities of Debremarkos town North west Ethiopia...
May 16, 2018: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29766175/bismuth-as-a-versatile-cation-for-luminescence-in-coordination-polymers-from-bix-3-4-4-bipy-understanding-of-photophysics-by-quantum-chemical-calculations-and-structural-parallels-to-lanthanides
#5
Jens R Sorg, Tobias Wehner, Philipp R Matthes, Rebecca Sure, Stefan Grimme, Johanna Heine, Klaus Müller-Buschbaum
Coordination polymers (CPs) with bismuth(iii) as a connectivity centre have been prepared from BiX3 (X = Cl-I) and 4,4'-bipyridine (bipy) in order to implement Bi-based luminescence. The products were obtained via different synthetic routes such as solution chemistry, melt syntheses or mechanochemical reactions. Five neutral and anionic 1D-CPs are presented that show a chemical parallel to trivalent lanthanides forming isostructural or closely related 1D-CPs, of which five additional compounds are described...
May 16, 2018: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/29765963/alopecic-and-aseptic-nodules-of-the-scalp-first-report-in-south-america-and-second-in-america
#6
Cristián Fischer-Levancini, Matías Gompertz, Antonio Guglielmetti, Héctor Opazo
Alopecic and aseptic nodules of the scalp, also named pseudocysts of the scalp, are a relatively new, little-known, and for sure underdiagnosed disease. It affects mostly young men and is characterized by a solitary or a few dome-shaped nodules accompanied by nonscarring alopecia, deep inflammatory infiltration in the skin biopsy specimen, and, in most cases, granulomas. It has a good response to doxycycline, intralesional corticosteroids, or drainage/aspiration of the lesion. We present a case report and a summary of the published cases...
April 2018: Skin Appendage Disorders
https://www.readbyqxmd.com/read/29764458/cone-beam-computed-tomography-in-implant-dentistry-recommendations-for-clinical-use
#7
Reinhilde Jacobs, Benjamin Salmon, Marina Codari, Bassam Hassan, Michael M Bornstein
BACKGROUND: In implant dentistry, three-dimensional (3D) imaging can be realised by dental cone beam computed tomography (CBCT), offering volumetric data on jaw bones and teeth with relatively low radiation doses and costs. The latter may explain why the market has been steadily growing since the first dental CBCT system appeared two decades ago. More than 85 different CBCT devices are currently available and this exponential growth has created a gap between scientific evidence and existing CBCT machines...
May 15, 2018: BMC Oral Health
https://www.readbyqxmd.com/read/29764014/-comprehensive-treatment-of-335-patients-with-pyriform-sinus-carcinoma-by-surgery-via-the-paraglottic-space-approach
#8
W M Li, D M Wei, Y Qian, S D Cao, Y Xu, D Y Liu, D P Lei, X L Pan
Objective: To report the experience in comprehensive surgical treatment of pyriform sinus carcinoma via the paraglottic space approach. Methods: Three hundred and thirty-five cases with pyriform sinus carcinoma (according to UICC 2012 criteria, stage Ⅰ, 12 cases; Ⅱ, 36; Ⅲ, 79; Ⅳ, 208; T1, 26; T2, 139; T3, 121; T4, 49; cN0, 83; cN1, 61; cN2a-b, 118; cN2c, 71; cN3, 2) treated between 2006 and 2013 were retrospectively reviewed. There were 323 males and 12 females. Age aged from 36 to 80 years old with a median of 60 years old...
May 7, 2018: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
https://www.readbyqxmd.com/read/29763532/palliative-care-occupies-growing-presence-in-ed
#9
(no author information available yet)
As the benefits of palliative care become more evident in clinical trials, there is growing interest in making such resources available to patients at an earlier stage, such as the ED. However, experts note that emergency staff first must identify available resources and make sure that providers have the primary palliative care skills needed to effectively introduce the topic to appropriate patients and families. Research shows that initiating the call for a palliative care consult while the patient is in the ED can deliver quality-of-life benefits even three months later...
June 2017: ED Management: the Monthly Update on Emergency Department Management
https://www.readbyqxmd.com/read/29762553/a-collection-of-public-transport-network-data-sets-for-25-cities
#10
Rainer Kujala, Christoffer Weckström, Richard K Darst, Miloš N Mladenović, Jari Saramäki
Various public transport (PT) agencies publish their route and timetable information with the General Transit Feed Specification (GTFS) as the standard open format. Timetable data are commonly used for PT passenger routing. They can also be used for studying the structure and organization of PT networks, as well as the accessibility and the level of service these networks provide. However, using raw GTFS data is challenging as researchers need to understand the details of the GTFS data format, make sure that the data contain all relevant modes of public transport, and have no errors...
May 15, 2018: Scientific Data
https://www.readbyqxmd.com/read/29760830/patient-and-provider-perspectives-on-adherence-to-and-care-coordination-of-lynch-syndrome-surveillance-recommendations-findings-from-qualitative-interviews
#11
Jennifer L Schneider, Katrina A B Goddard, Kristin R Muessig, James V Davis, Alan F Rope, Jessica E Hunter, Susan K Peterson, Louise S Acheson, Sapna Syngal, Georgia L Wiesner, Jacob A Reiss
Background: Patients with a genetic variant associated with Lynch syndrome (LS) are recommended to undergo frequent and repeated cancer surveillance activities to minimize cancer-related morbidity and mortality. Little is known about how patients and primary care providers (PCPs) track and manage these recommendations. We conducted a small exploratory study of patient and PCP experiences with recommended LS surveillance activities and communication with family members in an integrated health care system...
2018: Hereditary Cancer in Clinical Practice
https://www.readbyqxmd.com/read/29760769/family-assessment-conversations-as-a-tool-to-support-families-affected-by-parental-mental-illness-a-retrospective-review-of-electronic-patient-journals
#12
Camilla Lauritzen, Anne Berit Kolmannskog, Anette Christine Iversen
Background: Previous research has shown a link between parental mental illness and adverse development in their offspring. In Norway, it is mandatory for health professionals to identify if patients in adult mental health services have children, and subsequently to provide support for the children. An important tool to detect if families are affected by parental mental illness and to assess if there is a need for further intervention is the Family Assessment Conversation. Family Assessment Conversations is potentially a powerful tool for communication with families affected by parental mental illness because it facilitates early identification of children at risk of various adversities due to the family situation...
2018: International Journal of Mental Health Systems
https://www.readbyqxmd.com/read/29755430/distribution-patterns-of-polyphosphate-metabolism-pathway-and-its-relationships-with-bacterial-durability-and-virulence
#13
Liang Wang, Jiawei Yan, Michael J Wise, Qinghua Liu, James Asenso, Yue Huang, Shiyun Dai, Zhanzhong Liu, Yan Du, Daoquan Tang
Inorganic polyphosphate (polyP) is a linear polymer of orthophosphate residues. It is reported to be present in all life forms. Experimental studies showed that polyP plays important roles in bacterial durability and virulence. Here we investigated the relationships of polyP with bacterial durability and virulence theoretically. Bacterial lifestyle, environmental persistence, virulence factors (VFs), and species evolution are all included in the analysis. The presence of seven genes involved in polyP metabolism ( ppk1 , ppk2 , pap , surE , gppA , ppnK , and ppgK ) and 2595 core VFs were verified in 944 bacterial reference proteomes for distribution patterns via HMMER...
2018: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29754855/sampled-data-based-vibration-control-for-structural-systems-with-finite-time-state-constraint-and-sensor-outage
#14
Falu Weng, Mingxin Liu, Weijie Mao, Yuanchun Ding, Feifei Liu
The problem of sampled-data-based vibration control for structural systems with finite-time state constraint and sensor outage is investigated in this paper. The objective of designing controllers is to guarantee the stability and anti-disturbance performance of the closed-loop systems while some sensor outages happen. Firstly, based on matrix transformation, the state-space model of structural systems with sensor outages and uncertainties appearing in the mass, damping and stiffness matrices is established...
May 10, 2018: ISA Transactions
https://www.readbyqxmd.com/read/29754259/decoding-the-volume-outcome-relationship-in-type-a-aortic-dissection
#15
REVIEW
Athanasios Antoniou, Mohamad Bashir, Amer Harky, Benjamin Adams, Rakesh Uppal
Over the past few decades, the advents in monitoring, imaging, diagnostics, and implementation of multidisciplinary team approach in Type A aortic dissection surgery resulted in improved surgical outcomes. One other factor that needed to be targeted and carefully analyzed was the volume-outcome relationship on hospital and surgeon level in the settings of Type A dissection. This surely sprung form reports which indicated that supercenters providing aortic services with concentrated expert and expertise were performing better than smaller centers...
May 12, 2018: General Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29753963/application-of-semi-automated-ultrasonography-on-nutritional-support-for-severe-acute-pancreatitis
#16
Ying Li, Yu Ye, Mei Yang, Haiying Ruan, Yuan Yu
OBJECTIVE: To evaluate the application value of semi-automated ultrasound on the guidance of nasogastrojejunal tube replacement for patients with acute severe pancreatitis (ASP), as well as the value of the nutritional support for standardized treatment in clinical practice. METHODS: The retrospective research was performed in our hospital, and 34 patients suffering from ASP were enrolled into this study. All these identified participants ever received CT scans in order to make definitive diagnoses...
April 25, 2018: Computerized Medical Imaging and Graphics: the Official Journal of the Computerized Medical Imaging Society
https://www.readbyqxmd.com/read/29752949/the-change-of-nuclear-lc3-distribution-in-acute-myeloid-leukemia-cells
#17
Guo Wenjian, Jin Jingrui, Pan Jiajia, Yao Rongxing, Li Xia, Huang Xin, Ma Zhixing, Huang Sujuan, Yan Xiao, Jin Jie, Dong Aishu
Making sure the change of nuclear LC3 distribution in the autophagy of acute myeloid leukemia (AML) cell and finding out the regulation mechanism may lead to a breakthrough for killing AML cells. Western blots were performed to assess the expression of autophagy proteins. Changes in the LC3 distribution were monitored by immunofluorescence assays together with western blots, and the expression levels of Sirt1, DOR, Beclin1, HMGB1, and AMPK mRNA were detected via fluorescent quantitative PCR. The effects of Sirt1 and DOR on cell proliferation and survival were analyzed by MTT, flow cytometry, and western blotting assays...
May 9, 2018: Experimental Cell Research
https://www.readbyqxmd.com/read/29751444/lessons-learned-from-studies-with-the-freshwater-mussel-dreissena-polymorpha-exposed-to-platinum-palladium-and-rhodium
#18
Sonja Zimmermann, Bernd Sures
The platinum group elements (PGE) platinum, palladium and rhodium gain increasing (eco-)toxicological interest due to their cumulative introduction into ecosystems. So far, most PGE exposure studies investigating biological availability, uptake and bioaccumulation of PGE as well as their effects on different toxicological endpoints were performed under non-standardized conditions which occasionally make an interpretation and comparison of the results difficult. Here we compare the results of different PGE exposure studies with zebra mussels (Dreissena polymorpha) showing influences due to the PGE source, the exposure medium, the exposure concentration and period as well as the test system...
February 15, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/29746815/exact-and-approximate-limit-behaviour-of-the-yule-tree-s-cophenetic-index
#19
Krzysztof Bartoszek
In this work we study the limit distribution of an appropriately normalized cophenetic index of the pure-birth tree conditioned on n contemporary tips. We show that this normalized phylogenetic balance index is a submartingale that converges almost surely and in L2 . We link our work with studies on trees without branch lengths and show that in this case the limit distribution is a contraction-type distribution, similar to the Quicksort limit distribution. In the continuous branch case we suggest approximations to the limit distribution...
May 7, 2018: Mathematical Biosciences
https://www.readbyqxmd.com/read/29745199/-effects-of-fertilizing-regime-and-planting-age-on-soil-calcium-decline-in-luochuan-apple-orchards
#20
Peng Li, Chun Yue Li, Yi Quan Wang, Cai Qiang Jiao
This study was conducted to assess the effects of fertilizing regime and orchard planting age on soil calcium contents and stocks in the apple orchards on the Loess Plateau. The apple orchards in Luochuan County, one of the best regions for apple plantation in the world, were selec-ted in this study. The contents of calcium carbonate,water-soluble calcium and exchangeable cal-cium at 0-100 cm soil layer under different fertilizing regimes and various planting ages were mea-sured, their stocks were calculated and their variation features were analyzed...
May 18, 2017: Ying Yong Sheng Tai Xue Bao, the Journal of Applied Ecology
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