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https://www.readbyqxmd.com/read/27913033/nurse-practitioner-prescribing-in-australia-a-comprehensive-literature-review
#1
REVIEW
Jacqueline Fong, Thomas Buckley, Andrew Cashin, Lisa Pont
BACKGROUND: In Australia, the nurse practitioner (NP) obtained prescriptive authority in some jurisdictions in 2001. One of the key aspects in which the scope of NPs differs from Registered Nurses (RNs) relates to the legal privilege to prescribe medications. Although NPs have had prescriptive authority in Australia since 2001, with access to the Commonwealth subsidy scheme (PBS) since 2010, little is known about NPs prescriptive patterns or outcomes of prescriptive practice. AIM: The aim of this scoping review was to examine the extent, range and nature of research conducted in relation to NP prescribing in the Australian health context as well as identify gaps in the existing literature...
November 29, 2016: Australian Critical Care: Official Journal of the Confederation of Australian Critical Care Nurses
https://www.readbyqxmd.com/read/27912750/fermented-barley-and-soybean-bs-mixture-enhances-intestinal-barrier-function-in-dextran-sulfate-sodium-dss-induced-colitis-mouse-model
#2
Jong Kyu Woo, Seungho Choi, Ju-Hee Kang, Dae Eung Kim, Byung-Serk Hurh, Jong-Eun Jeon, Sun Yeou Kim, Seung Hyun Oh
BACKGROUND: Inflammatory bowel disease (IBD) is characterized by chronic or relapsing immune system activation and inflammation within the gastrointestinal tract. The lack of safety and efficacy of standard therapies, the use of food supplements for managing IBD is increasing, and many studies have reported that various food supplements provide many beneficial effects for the IBD. METHODS: This study aimed to evaluate the anti-colitis effects of dietary supplementation with a fermented barley and soybean mixture (BS) on intestinal inflammation using a murine model of IBD...
December 3, 2016: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/27912212/knockdown-of-inhibitory-guanine-nucleotide-binding-protein-gi%C3%AE-2-by-antisense-oligodeoxynucleotides-attenuates-the-development-of-hypertension-and-tachycardia-in-spontaneously-hypertensive-rats
#3
Yousra Ali El-Basyuni, Yuan Li, Madhu B Anand-Srivastava
BACKGROUND: We previously showed that the levels of both Giα-2 and Giα-3 proteins were augmented in spontaneously hypertensive rats (SHRs) before the onset of hypertension. In addition, intraperitoneal injection of pertussis toxin, which inactivates both Giα proteins, prevented the development of hypertension in SHRs. The aim of the present study was to determine the specific contributions of Giα-2 and Giα-3 proteins to the development of hypertension. METHODS AND RESULTS: Antisense oligodeoxynucleotide of Giα-2 and Giα-3 encapsulated in PEG/DOTAP/DOPE cationic liposomes were administrated intravenously into 3-week-old prehypertensive SHRs and Wistar Kyoto rats, whereas the control Wistar Kyoto rats and SHRs received PBS, empty liposomes, or sense...
October 26, 2016: Journal of the American Heart Association
https://www.readbyqxmd.com/read/27910815/in-vitro-and-in-vivo-evaluations-of-a-novel-post-electrospinning-treatment-to-improve-the-fibrous-structure-of-chitosan-membranes-for-guided-bone-regeneration
#4
Hengjie Su, Kwei-Yu Liu, Anastasios Karydis, Daniel G Abebe, Chaoxi Wu, Kenneth M Anderson, Najib Ghadri, Pradeep Adatrow, Tomoko Fujiwara, Joel D Bumgardner
Electrospun chitosan membranes have been investigated for guided bone regeneration but are susceptible to swelling, dissolution, and loss of biomimetic nanofiber structure due to residual acid salts. A novel process was investigated for acidic salt removal from chitosan electrospun in 70% trifluoroacetic acid (TFA) by treating with triethylamine (TEA)/acetone and di-tert-butyl dicarbonate (tBOC) instead of the common Na2CO3 treatment. TFA salt removal and nanofiber structure stabilization were confirmed by EDS, FTIR, (19)F NMR and electron microscopy before and after soaking in water...
December 2, 2016: Biomedical Materials
https://www.readbyqxmd.com/read/27910202/isopropanol-dehydration-on-amorphous-silica-alumina-synergy-of-br%C3%A3-nsted-and-lewis-acidities-at-pseudo-bridging-silanols
#5
Kim Larmier, Céline Chizallet, Sylvie Maury, Nicolas Cadran, Johnny Abboud, Anne-Félicie Lamic-Humblot, Eric Marceau, Hélène Lauron-Pernot
The mechanism of isopropanol dehydration on amorphous silica-alumina (ASA) was unraveled by a combination of experimental kinetic measurements and periodic density functional theory (DFT) calculations. We show that pseudo-bridging silanols (PBS-Al) are the most likely active sites owing to the synergy between the Brønsted and Lewis acidic properties of these sites, which facilitates the activation of alcohol hydroxy groups as leaving groups. Isopropanol dehydration was used to specifically investigate these PBS-Al sites, whose density was estimated to be about 10(-1)  site nm(-2) on the silica-doped alumina surface under investigation, by combining information from experiments and theoretical calculations...
December 2, 2016: Angewandte Chemie
https://www.readbyqxmd.com/read/27909553/effects-of-gangliosides-from-deer-bone-extract-on-the-gene-expressions-of-matrix-metalloproteinases-and-collagen-type-ii-in-interleukin-1%C3%AE-induced-osteoarthritic-chondrocytes
#6
Hyung Joo Suh, Hyunji Lee, Byung Jung Min, Sung Ug Jung, Eun Young Jung
BACKGROUND/OBJECTIVES: We investigated the anti-osteoarthritic effects of deer bone extract on the gene expressions of matrix metalloproteinases (MMPs) and collagen type II (COL2) in interleukin-1β-induced osteoarthritis (OA) chondrocytes. MATERIALS/METHODS: Primary rabbit chondrocytes were treated as follows: CON (PBS treatment), NC (IL-1β treatment), PC (IL-1β + 100 µg/mL glucosamine sulphate/chondroitin sulphate mixture), and DB (IL-1β + 100 µg/mL deer bone extract)...
December 2016: Nutrition Research and Practice
https://www.readbyqxmd.com/read/27909300/cyanobacterial-photoprotection-by-the-orange-carotenoid-protein
#7
REVIEW
Diana Kirilovsky, Cheryl A Kerfeld
In photosynthetic organisms, the production of dangerous oxygen species is stimulated under high irradiance. To cope with this stress, these organisms have evolved photoprotective mechanisms. One type of mechanism functions to decrease the energy arriving at the photochemical centres by increasing thermal dissipation at the level of antennae. In cyanobacteria, the trigger for this mechanism is the photoactivation of a soluble carotenoid protein, the orange carotenoid protein (OCP), which is a structurally and functionally modular protein...
December 2, 2016: Nature Plants
https://www.readbyqxmd.com/read/27908162/an-efficient-method-to-determine-double-gaussian-fluence-parameters-in-the-eclipse%C3%A2-proton-pencil-beam-model
#8
Jiajian Shen, Wei Liu, Joshua Stoker, Xiaoning Ding, Aman Anand, Yanle Hu, Michael G Herman, Martin Bues
PURPOSE: To find an efficient method to configure the proton fluence for a commercial proton pencil beam scanning (PBS) treatment planning system (TPS). METHODS: An in-water dose kernel was developed to mimic the dose kernel of the pencil beam convolution superposition algorithm, which is part of the commercial proton beam therapy planning software, eclipse™ (Varian Medical Systems, Palo Alto, CA). The field size factor (FSF) was calculated based on the spot profile reconstructed by the in-house dose kernel...
December 2016: Medical Physics
https://www.readbyqxmd.com/read/27907111/measuring-psychobiosocial-states-in-sport-initial-validation-of-a-trait-measure
#9
Claudio Robazza, Maurizio Bertollo, Montse C Ruiz, Laura Bortoli
We examined the item characteristics, the factor structure, and the concurrent validity of a trait measure of psychobiosocial states. In Study 1, Italian athletes (N = 342, 228 men, 114 women, Mage = 23.93, SD = 6.64) rated the intensity, the frequency, and the perceived impact dimensions of a psychobiosocial states scale, trait version (PBS-ST), which is composed of 20 items (10 functional and 10 dysfunctional) referring to how they usually felt before an important competition. In Study 2, the scale was cross validated in an independent sample (N = 251, 181 men, 70 women, Mage = 24...
2016: PloS One
https://www.readbyqxmd.com/read/27907095/phenotypic-plasticity-epigenetic-or-genetic-modifications-in-relation-to-the-duration-of-cd-exposure-within-a-microevolution-time-range-in-the-beet-armyworm
#10
Maria Augustyniak, Anna Płachetka-Bożek, Alina Kafel, Agnieszka Babczyńska, Monika Tarnawska, Agnieszka Janiak, Anna Loba, Marta Dziewięcka, Julia Karpeta-Kaczmarek, Agnieszka Zawisza-Raszka
In the case of the pests inhabiting metal polluted or fields where the use of pesticides is common, a natural selection of resistant individuals can occur. This may pose serious problems for humans, agriculture, as well as the economies of many countries. In this study, the hypothesis that multigenerational (120 generations) exposure to cadmium of a beet armyworm population could be a selecting factor toward a more efficient DNA protection was verified. The hemocytes of individuals from two culture strains (control and Cd-exposed) were treated with H2O2 (a DNA-damaging agent) or PBS (reference)...
2016: PloS One
https://www.readbyqxmd.com/read/27903452/acute-stress-induced-the-hemolytic-activity-of-the-complement-system-%C3%AE-glucan-induced-cortisol-levels-improve-the-early-immune-response-in-matrinx%C3%A3-brycon-amazonicus
#11
Luz N Franco Montoya, Talísia P Martins, Rodrigo Y Gimbo, Fábio S Zanuzzo, Elisabeth C Urbinati
This study investigated the role of endogenous cortisol on the innate immune response in matrinxã (Brycon amazonicus) fed with β-glucan, prior to and after stressor exposure and bacterial challenge. For this, we evaluated the serum cortisol and plasma glucose levels, the serum lysozyme levels, the hemolytic activity of the complement system, and the respiratory activity of leukocytes, as well as the number of circulating erythrocytes and leukocytes of fish fed during 15 days with diets containing β-glucan 0...
November 26, 2016: Fish & Shellfish Immunology
https://www.readbyqxmd.com/read/27901382/assessment-of-in-vitro-release-of-carboplatin-from-six-carrier-media
#12
Marije Risselada, Denis J Marcellin-Little, Kristen M Messenger, Emily Griffith, Gigi S Davidson, Mark G Papich
OBJECTIVE To investigate in vitro carboplatin release from 6 carrier media. SAMPLE 6 carboplatin-containing carrier media. PROCEDURES An in vitro release study was performed with 6 commercially available carrier media: a hemostatic gelatin sponge, a poloxamer copolymer gel, and 2 sizes (3 and 4.8 mm in diameter) of beads molded from each of 2 commercial calcium sulfate products. All carrier media contained 10 mg of carboplatin. Carrier media specimens were placed in 37°C PBS solution for 96 hours. Carboplatin concentrations in PBS solution were measured by use of high-performance liquid chromatography at 15 time points to calculate the amount and proportion of carboplatin released from each specimen...
December 2016: American Journal of Veterinary Research
https://www.readbyqxmd.com/read/27901148/ligand-dependent-exciton-dynamics-and-photovoltaic-properties-of-pbs-quantum-dot-heterojunction-solar-cells
#13
Jin Chang, Yuhei Ogomi, Chao Ding, Yao Hong Zhang, Taro Toyoda, Shuzi Hayase, Kenji Katayama, Qing Shen
The surface chemistry of colloidal quantum dots (QDs) plays an important role in determining the photoelectric properties of QD films and the corresponding quantum dot heterojunction solar cells (QDHSCs). To investigate the effects of the ligand structure on the photovoltaic performance and exciton dynamics of QDHSCs, PbS QDHSCs were fabricated by the solid state ligand exchange method with mercaptoalkanoic acid as the cross-linking ligand. Temperature-dependent photoluminescence and ultrafast transient absorption spectra show that the electronic coupling and charge transfer rate within QD ensembles were monotonically enhanced as the ligand length decreased...
November 30, 2016: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/27900440/role-of-methotrexate-chronotherapy-in-collagen-induced-rheumatoid-arthritis-in%C3%A2-rats
#14
X Wang, X Yan, F Wang, F Ge, Z Li
AIM: To explore the circadian rhythm of serum interleukin (IL)-6 in collagen-induced arthritis (CIA) rats and compare the safety and effectiveness of methotrexate (MTX) administered traditionally and via chronotherapy. METHODS: CIA rat models were immunized with bovine type II collagen. Serum IL-6 levels in normal and CIA rats were measured at 2, 6, 10, 14, 18, or 22 h after the light was turned on (HALO). MTX was administered to 6 HALO/18 HALO experimental groups of Wistar rats once daily according to the IL-6 rhythm...
November 29, 2016: Zeitschrift Für Rheumatologie
https://www.readbyqxmd.com/read/27899275/immunological-consequences-of-immunization-with-tumor-lysate-vaccine-and-propranolol-as-an-adjuvant-a-study-on-cytokine-profiles-in-breast-tumor-microenvironment
#15
Somayeh Ashrafi, Reza Shapouri, Mehdi Mahdavi
In this study, we sought out to study the anti-cancer effects of propranolol (Pro) in combination with tumor lysate vaccine on lymphocyte proliferation activities as well as on IL-2, IL-4, IL-10, IL-12, IL-17 and IFN-γ cytokine concentration in the tumor microenvironment (TME). A tumor model was established in inbred Balb/C mice using transplantation of tumor to the flank of native mice. Tumor-bearing mice were immunized with lysate tumor cells (vaccine), a combination of Pro/Vaccine (Vac). Control groups consisted of tumor-bearing mice receiving only propranolol or PBS three times with one week interval via subcutaneous (s...
November 26, 2016: Immunology Letters
https://www.readbyqxmd.com/read/27898968/post-artificial-insemination-supplementation-with-calcium-salts-of-soybean-oil-influences-pregnancy-establishment-factors-in-beef-cows
#16
R S Cipriano, R F Cooke, A D Rodrigues, L G T Silva, D W Bohnert, R S Marques, J L M Vasconcelos, A V Pires, R L A Cerri
The objective of this experiment was to compare hormonal, uterine, and conceptus factors associated with pregnancy establishment in beef cows supplemented or not with Ca salts of soybean oil (CSSO) for 21 d beginning after timed AI. One hundred lactating multiparous Nelore cows were allocated to 20 groups of 5 cows/group and timed inseminated on d 0 of the experiment. After AI, groups were randomly assigned to receive (as-fed basis) 100 g of protein-mineral mix + 100 g of ground corn per cow per day, in addition to 1) 100 g/cow daily of CSSO ( = 10) or 2) 100 g/cow daily of kaolin (CON; rumen-inert indigestible substance; = 10)...
November 2016: Journal of Animal Science
https://www.readbyqxmd.com/read/27898826/quantitative-trait-loci-mapping-for-tillering-related-traits-in-two-switchgrass-populations
#17
Dan Chang, Yanqi Wu, Linglong Liu, Shuiyi Lu-Thames, Hongxu Dong, Carla Goad, Shiqie Bai, Shiva Makaju, Tilin Fang
Plant tillering and related traits are morphologically important components contributing to switchgrass ( L.) biomass yield. The objectives of this study were to estimate broad-sense heritabilities for tillering-related traits, to analyze correlations between biomass yield and the traits, and to identify quantitative trait loci (QTL) for them. A first-generation selfed population of NL94 plant and a hybrid population between NL94 and SL93 plants were field established in a randomized complete block design with three replications in Stillwater and Perkins, OK...
July 2016: Plant Genome
https://www.readbyqxmd.com/read/27898654/effect-of-bone-marrow-mesenchymal-stem-cells-on-satellite-cell-proliferation-and-apoptosis-in-immobilization-induced-muscle-atrophy-in-rats
#18
Tie-Shan Li, Hao Shi, Lin Wang, Chuanzhu Yan
BACKGROUND Muscle atrophy due to disuse occurs along with adverse physiological and functional changes, but bone marrow stromal cells (MSCs) may be able to act as muscle satellite cells to restore myofibers. Thus, we investigated whether MSCs could enhance the proliferation of satellite cells and suppress myonuclear apoptosis during immobilization. MATERIAL AND METHODS We isolated, purified, amplified, and identified MSCs. Rats (n=48) were randomized into 3 groups: WB group (n=16), IM-PBS group (n=16), and IM-MSC (n=16)...
November 29, 2016: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/27897137/photoluminescence-properties-of-lead-selenide-produced-by-selenization-and-a-solvothermal-method
#19
Jungdong Kim, Hak-Young Ahn, Seung Gi Kim, Eunsoon Oh, Byeong-Kwon Ju, Won Jun Choi, So-Hye Cho
We studied temperature-dependent photoluminescence (PL) spectra of lead selenide (PbSe) dendrites and cubes grown by a solvothermal method. Their PL peaks were located at ∼8 μm at 10 K with a full width at half maximum (FWHM) of 10 meV. Using the temperature-dependent FWHM values, we obtained carrier-phonon coupling coefficients for PbSe. We also demonstrated mechanochemical synthesis of polycrystalline PbS nanoparticles and their successful conversion into a PbSe layer composed of nanocrystals by a selenization process with thermal treatment...
November 29, 2016: Nanotechnology
https://www.readbyqxmd.com/read/27895483/improved-proliferation-of-antigen-specific-cytolytic-t-lymphocytes-using-a-multimodal-nanovaccine
#20
Bo Li, Michael Siuta, Vanessa Bright, Dmitry Koktysh, Brittany K Matlock, Megan E Dumas, Meiying Zhu, Alex Holt, Donald Stec, Shenglou Deng, Paul B Savage, Sebastian Joyce, Wellington Pham
The present study investigated the immunoenhancing property of our newly designed nanovaccine, that is, its ability to induce antigen-specific immunity. This study also evaluated the synergistic effect of a novel compound PBS-44, an α-galactosylceramide analog, in boosting the immune response induced by our nanovaccine. The nanovaccine was prepared by encapsulating ovalbumin (ova) and an adjuvant within the poly(lactic-co-glycolic acid) nanoparticles. Quantitative analysis of our study data showed that the encapsulated vaccine was physically and biologically stable; the core content of our nanovaccine was found to be released steadily and slowly, and nearly 90% of the core content was slowly released over the course of 25 days...
2016: International Journal of Nanomedicine
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