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https://www.readbyqxmd.com/read/28531120/antidiabetic-effects-of-tea
#1
REVIEW
Qiu-Yue Fu, Qing-Sheng Li, Xiao-Ming Lin, Ru-Ying Qiao, Rui Yang, Xu-Min Li, Zhan-Bo Dong, Li-Ping Xiang, Xin-Qiang Zheng, Jian-Liang Lu, Cong-Bo Yuan, Jian-Hui Ye, Yue-Rong Liang
Diabetes mellitus (DM) is a chronic endocrine disease resulted from insulin secretory defect or insulin resistance and it is a leading cause of death around the world. The care of DM patients consumes a huge budget due to the high frequency of consultations and long hospitalizations, making DM a serious threat to both human health and global economies. Tea contains abundant polyphenols and caffeine which showed antidiabetic activity, so the development of antidiabetic medications from tea and its extracts is increasingly receiving attention...
May 20, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28524171/endocrine-disrupting-chemicals-and-fatty-liver-disease
#2
REVIEW
Charles E Foulds, Lindsey S Treviño, Brian York, Cheryl L Walker
A growing epidemic of nonalcoholic fatty liver disease (NAFLD) is paralleling the increase in the incidence of obesity and diabetes mellitus in countries that consume a Western diet. As NAFLD can lead to life-threatening conditions such as cirrhosis and hepatocellular carcinoma, an understanding of the factors that trigger its development and pathological progression is needed. Although by definition this disease is not associated with alcohol consumption, exposure to environmental agents that have been linked to other diseases might have a role in the development of NAFLD...
May 19, 2017: Nature Reviews. Endocrinology
https://www.readbyqxmd.com/read/28524168/endocrine-disrupting-chemicals-and-the-regulation-of-energy-balance
#3
REVIEW
Angel Nadal, Ivan Quesada, Eva Tudurí, Rubén Nogueiras, Paloma Alonso-Magdalena
Energy balance involves the adjustment of food intake, energy expenditure and body fat reserves through homeostatic pathways. These pathways include a multitude of biochemical reactions, as well as hormonal cues. Dysfunction of this homeostatic control system results in common metabolism-related pathologies, which include obesity and type 2 diabetes mellitus. Metabolism-disrupting chemicals (MDCs) are a particular class of endocrine-disrupting chemicals that affect energy homeostasis. MDCs affect multiple endocrine mechanisms and thus different cell types that are implicated in metabolic control...
May 19, 2017: Nature Reviews. Endocrinology
https://www.readbyqxmd.com/read/28522822/physical-activity-and-risk-of-comorbidities-in-patients-with-chronic-obstructive-pulmonary-disease-a-cohort-study
#4
Tsung Yu, Gerben Ter Riet, Milo A Puhan, Anja Frei
Multi-morbidity is common in patients with chronic obstructive pulmonary disease and low levels of physical activity are hypothesized to be an important risk factor. The current study aimed to assess the longitudinal association between physical activity and risk of seven categories of comorbidity in chronic obstructive pulmonary disease patients. The study included 409 patients from primary care practice in the Netherlands and Switzerland. We assessed physical activity using the Longitudinal Ageing Study Amsterdam Physical Activity Questionnaire at baseline and followed patients for up to 5 years...
May 18, 2017: NPJ Primary Care Respiratory Medicine
https://www.readbyqxmd.com/read/28521190/simultaneous-determination-of-bisphenol-a-and-estrogens-in-hair-samples-by-liquid-chromatography-electrospray-tandem-mass-spectrometry
#5
Chaelin Lee, Chong Hyeak Kim, Sunghwan Kim, Sung-Hee Cho
Bisphenol A (BPA), an endocrine disrupter, is widely used to make chemicals for polycarbonate, plastics, beverage containers, epoxy resins, and cash register receipts. BPA is one of the known xenoestrogens, which have weak estrogenic activity and cause obesity, diabetes, breast cancer, and reproductive disorders. Even though the concentration level of metabolomes in hair is usually lower than that in urine and blood, there are several reasons why we chose to use hair samples. First, the sampling procedure of hairs is simple...
May 11, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/28516806/is-bisphenol-a-exposure-associated-with-the-development-of-glucose-intolerance-and-increased-insulin-resistance-in-thais
#6
La-Or Chailurkit, Pechngam Tengpraettanakorn, Suwannee Chanprasertyotin, Boonsong Ongphiphadhanakul
Bisphenol A (BPA), the monomeric component of polycarbonate plastics, reportedly possesses endocrine-disrupting effects. Exposure to low levels of BPA during more vulnerable periods leads to abnormalities related to sexual development in experimental animals. Moreover, recently a few epidemiological studies in Caucasians have demonstrated the association of BPA exposure with type 2 diabetes. Therefore, in the present study we examined the association of BPA exposure and abnormal glucose tolerance in Thais. This is a cross-sectional study of 240 participants aged at least 50 years, randomly selected by computer-generated random numbers within each glucose tolerance status from an oral glucose tolerance study of 661 participants...
January 1, 2017: Nutrition and Health
https://www.readbyqxmd.com/read/28512448/the-potential-role-of-contraction-induced-myokines-in-the-regulation-of-metabolic-function-for-the-prevention-and-treatment-of-type-2-diabetes
#7
REVIEW
Brian P Carson
Skeletal muscle represents the largest organ in the body, comprises 36-42% of body weight, and has recently been recognized as having an endocrine function. Proteins expressed and released by muscle that have autocrine, paracrine, and endocrine bioactivities have been termed myokines. It is likely that muscle contraction represents the primary stimulus for the synthesis and secretion of myokines to enable communication with other organs such as the liver, adipose tissue, brain, and auto-regulation of muscle metabolism...
2017: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/28512134/management-of-endocrine-disease-suicide-risk-in-patients-with-diabetes-a-systematic-review-and-meta-analysis
#8
Bin Wang, Xiaofei An, Xiaohong Shi, Jin-An Zhang
BACKGROUND: Previous studies investigating the risk of suicide in diabetes patients reported controversial findings. We did a systematic review and meta-analysis to comprehensively estimate the risk and incidence rate of suicide in diabetic patients. METHODS: Pubmed, Embase, and PsycINFO were searched for eligible studies. Random-effects meta-analysis was used to calculate the relative risk (RR) and the incidence rate of suicide in diabetes patients. We also calculated the proportion of deaths attributable to suicide among diabetes patients...
May 16, 2017: European Journal of Endocrinology
https://www.readbyqxmd.com/read/28511371/study-of-serum-total-psa-and-free-psa-as-an-oncological-marker-in-breast-tumour
#9
Elteza Tahjiba Jahir, Runi Devi, Bibhuti Bhushan Borthakur
INTRODUCTION: Breast Cancer (BC) cases are rising alarmingly all over the world and India is not an exception. This rising trend is due to an increased age at first child birth, decreased breast feeding, and the changing lifestyle mostly in urban India. With the advent of more sensitive methodologies and research works in this field, it has been suggested that Prostate Specific Antigen (PSA) plays an important role in the pathogenesis of breast cancer besides other established tumour markers...
March 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28509114/implicating-the-potential-role-of-orexin-in-hypertension
#10
REVIEW
Monika Rani, Raghuvansh Kumar, Pawan Krishan
Orexins (orexin A and orexin B), neuropeptides of hypothalamic origin also known as hypocretins, have been well documented for regulating the different physiological functions including feeding, sleep wakefulness, stress, and reward. However, from the past few years, orexins have evolved as an emerging biomarker for various endocrine disorders including diabetes mellitus and obesity which ultimately leads to various cardiovascular risk factors. Orexins exist in two isoforms orexin A and orexin B and exert their effect by acting on the G protein-coupled receptors orexin 1 receptor (OX1R) and orexin 2 receptor (OX2R)...
May 16, 2017: Naunyn-Schmiedeberg's Archives of Pharmacology
https://www.readbyqxmd.com/read/28508600/endocrine-disorders-developing-after-surgical-intervention-of-craniopharyngioma-in-children
#11
Kyrillus S Shohdy, Wegdan Rashad
Craniopharyngiomas, albeit their benign nature, can cause severe damage to visual, hypothalamic, endocrine and neurologic functions which make their total resection an inevitable approach to save the patient's life. However, significant therapy-related long term complications make those traditional treatment options debatable and hazardous. This review will focus on the various complications that affect the childrens' quality of life considerably such as, diabetes insipidus, precocious puberty and hypothalamic obesity...
March 2017: Pediatric Endocrinology Reviews: PER
https://www.readbyqxmd.com/read/28507197/muscle-adipose-tissue-cross-talk
#12
Kristin I Stanford, Laurie J Goodyear
Exercise training results in adaptations to both skeletal muscle and white adipose tissue (WAT) and protects against metabolic disorders including obesity and type 2 diabetes. Exercise-induced adaptations include an altered profile of secreted proteins, both myokines (from skeletal muscle) and adipokines (from adipose tissue). These secreted proteins may act in an endocrine manner to facilitate tissue-to-tissue communication and "cross talk," likely working together to improve overall metabolic health. Some studies suggest that contracting skeletal muscles release myokines that may function to alter the phenotype of WAT, including WAT "beiging," in which there is increased expression of beige marker genes and increased presence of multilocular cells within the WAT...
May 15, 2017: Cold Spring Harbor Perspectives in Medicine
https://www.readbyqxmd.com/read/28506430/george-e-palade-memorial-lecture-my-life-in-pancreatic-research-unexpected-results-may-open-the-door
#13
REVIEW
Makoto Otsuki
The Palade Prize is the most distinguished award of the IAP for achievement in pancreatic research. It is named after George E. Palade, who in 1974 was awarded the Nobel Prize for his work on protein trafficking in pancreatic acinar cells. It is a great honor to be awarded the 2016 Palade Prize. While I was in graduate school, I was conducting research on hypothalamo-pituitary-thyroid axis; after finishing graduate school, I began research on amylase isoenzymes. This was the first step of my pancreatic research...
May 6, 2017: Pancreatology: Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]
https://www.readbyqxmd.com/read/28506340/-endocrine-and-metabolic-features-of-female-children-with-prader-willi-syndrome-an-analysis-of-4-cases
#14
Mo-Ling Wu, Juan Li, Yu Ding, Yao Chen, Guo-Ying Chang, Xiu-Min Wang, Jian Wang, Yi-Ping Shen
This article reports the clinical features and endocrine and metabolic features of 4 children with Prader-Willi syndrome (PWS). All the patients were female and aged 6-12 years at diagnosis. All of them had clinical manifestations of obesity, unusual facies, developmental retardation, and intellectual disability. Genetic detection showed that 2 patients had paternal deletion of the 15q11.2-q13 region, one patient had maternal autodiploid in the 15q11.2-q13 region, and one patient had no abnormality in the 15q11...
May 2017: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://www.readbyqxmd.com/read/28505316/pancreas-atrophy-and-islet-amyloid-deposition-in-patients-with-elderly-onset-type-2-diabetes
#15
An Xin, Hiroki Mizukami, Wataru Inaba, Taro Yoshida, Yu-Ki Takeuchi, Soroku Yagihashi
Context: With prolonged life-expectancy, we often encounter patients with elderly onset type 2 diabetes (eT2DM). Although clinical features of eT2DM are suggested to be different from those in patients with middle-aged onset type 2 diabetes (mT2DM), islet pathology in eT2DM has not been addressed. Objective: We attempted to characterize the pancreatic pathology in eT2DM and sought for its clinical implication. Methods: Pancreata from 13 young non-diabetic (20-29 y...
May 12, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28504618/butyrate-reduces-high-fat-diet-induced-metabolic-alterations-hepatic-steatosis-and-pancreatic-beta-cell-and-intestinal-barrier-dysfunctions-in-prediabetic-mice
#16
V A Matheus, Lcs Monteiro, R B Oliveira, D A Maschio, C B Collares-Buzato
In this study, we investigated the effect of diet supplementation with sodium butyrate (5% w/w), a short-chain fatty acid produced by the intestinal microbiota, on metabolic parameters, body adiposity, hepatic and pancreatic lipid accumulation, beta cell function/mass as well as on the structure and function of the tight junction-mediated intestinal epithelial barrier in both normal and obese/prediabetic C57 mice fed a regular (control) or high-fat diet for 60 days, respectively. Butyrate treatment significantly inhibited all the high-fat-induced metabolic dysfunctions evaluated, i...
January 1, 2017: Experimental Biology and Medicine
https://www.readbyqxmd.com/read/28503277/prevalence-of-diabetes-impaired-fasting-glucose-and-impaired-glucose-tolerance-in-patients-with-thalassemia-major-in-iran-a-meta-analysis-study
#17
REVIEW
Milad Azami, Ali Sharifi, Siros Norozi, Akram Mansouri, Kourosh Sayehmiri
BACKGROUND: This study aimed to investigate the prevalence of diabetes, impaired fasting glucose (IFG) and impaired glucose tolerance (IGT) in Iranian patients with thalassemia major. METHODS: The current study has been conducted based on PRISMA guideline. To obtain the documents, Persian and English scientific databases such as Magiran, Iranmedex, SID, Medlib, IranDoc, Scopus, PubMed, ScienceDirect, Cochrane, Web of Science, Springer, Wiley Online Library as well as Google Scholar were searched until December 2015...
2017: Caspian Journal of Internal Medicine
https://www.readbyqxmd.com/read/28500781/pregnancy-outcomes-in-simultaneous-pancreas-and-kidney-transplant-recipients-a-national-french-survey-study
#18
G Normand, F Brunner, L Badet, F Buron, M Catton, J Massardier, L Esposito, P Grimbert, G Mourad, J E Serre, S Caillard, G Karam, D Cantarovich, E Morelon, O Thaunat
Simultaneous pancreas and kidney transplantation (SPK) is currently the best therapeutic option for patients with type-1 diabetes and terminal renal failure. Renal transplantation restores fertility enabling women to pursue pregnancies. However, scarcity of available data on pregnancy outcomes in SPK impedes fair medical counseling. Medical files of all pregnancies that lasted ≥3 months among recipients of functional SPK performed between 1990 and 2015 in France were retrospectively analyzed. Twenty-six pregnancies in 22 SPK recipients were identified...
May 13, 2017: Transplant International: Official Journal of the European Society for Organ Transplantation
https://www.readbyqxmd.com/read/28496408/the-impact-of-microbiota-gut-brain-axis-on-diabetic-cognition-impairment
#19
REVIEW
Youhua Xu, Hua Zhou, Quan Zhu
Progressive cognitive dysfunction is a central characteristic of diabetic encephalopathy (DE). With an aging population, the incidence of DE is rising and it has become a major threat that seriously affects public health. Studies within this decade have indicated the important role of risk factors such as oxidative stress and inflammation on the development of cognitive impairment. With the recognition of the two-way communication between gut and brain, recent investigation suggests that "microbiota-gut-brain axis" also plays a pivotal role in modulating both cognition function and endocrine stability...
2017: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/28494504/metabolic-syndrome-and-aggressive-prostate-cancer-at-initial-diagnosis
#20
Simona Di Francesco, Raffaele L Tenaglia
Links between metabolic syndrome and prostate cancer after androgen deprivation therapy are emerging. The aim of the research was to investigate the association of metabolic syndrome and aggressive prostate malignancy, at initial diagnosis, without the influence of hormonal treatment. Retrospective analysis of 133 patients with prostate tumor diagnosis between 2007 and 2009 was conducted. Patients with prostate cancer were subdivided in 2 groups according to Gleason score: Gleason score≥7 as high-grade prostate tumor (Group 1) and <7 (Group 2) as low-grade prostate tumor...
May 11, 2017: Hormone and Metabolic Research, Hormon- und Stoffwechselforschung, Hormones et Métabolisme
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