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https://www.readbyqxmd.com/read/28572941/effect-of-psyllium-and-gum-arabic-biopolymers-on-the-survival-rate-and-storage-stability-in-yogurt-of-enterococcus%C3%A2-duransiw3-encapsulated-in-alginate
#1
Yousef Nami, Babak Haghshenas, Ahmad Yari Khosroushahi
Different herbal biopolymers were used to encapsulate Enterococcus durans IW3 to enhance its storage stability in yogurt and subsequently its endurance in gastrointestinal condition. Nine formulations of encapsulation were performed using alginate (ALG), ALG-psyllium (PSY), and ALG-gum Arabic (GA) blends. The encapsulation efficiency of all formulations, tolerance of encapsulated E. durans IW3 against low pH/high bile salt concentration, storage lifetime, and release profile of cells in natural condition of yogurt were evaluated...
May 2017: Food Science & Nutrition
https://www.readbyqxmd.com/read/28550604/microencapsulation-of-%C3%AE-carotene-based-on-casein-guar-gum-blend-using-zeta-potential-yield-stress-phenomenon-an-approach-to-enhance-photo-stability-and-retention-of-functionality
#2
Deepika Thakur, Ashay Jain, Gargi Ghoshal, U S Shivhare, O P Katare
β-Carotene, abundant majorly in carrot, pink guava yams, spinach, kale, sweet potato, and palm oil, is an important nutrient for human health due to its scavenging action upon reactive free radicals wherever produced in the body. Inclusion of liposoluble β-carotene in foods and food ingredients is a challenging aspect due to its labile nature and low absorption from natural sources. This fact has led to the application of encapsulation of β-carotene to improve stability and bioavailability. The present work was aimed to fabricate microcapsules (MCs) of β-carotene oily dispersion using the complex coacervation technique with casein (CA) and guar gum (GG) blend...
May 26, 2017: AAPS PharmSciTech
https://www.readbyqxmd.com/read/28506328/the-effect-of-dietary-faba-bean-and-non-starch-polysaccharide-degrading-enzymes-on-the-growth-performance-and-gut-physiology-of-young-turkeys
#3
D Mikulski, J Juskiewicz, B Przybylska-Gornowicz, E Sosnowska, B A Slominski, J Jankowski, Z Zdunczyk
The aim of this study was to investigate the effect of dietary replacement of soya bean meal (SBM) with faba bean (FB) and a blend of non-starch polysaccharide (NSP) degrading enzymes on the gastrointestinal function, growth performance and welfare of young turkeys (1 to 56 days of age). An experiment with a 2×2 factorial design was performed to compare the efficacy of four diets: a SBM-based diet and a diet containing FB, with and without enzyme supplementation (C, FB, CE and FBE, respectively). In comparison with groups C, higher dry matter content and lower viscosity of the small intestinal digesta were noted in groups FB...
May 16, 2017: Animal: An International Journal of Animal Bioscience
https://www.readbyqxmd.com/read/28504991/tablet-e-logbooks-four-thousand-clinical-cases-and-complications-e-logged-by-14-nondoctor-anesthesia-providers-in-nepal
#4
Shristi Shah, Oliver Ross, Stephen Pickering, Stephen Knoble, Indra Rai
BACKGROUND: To meet the need for essential surgery across rural Nepal, anesthesia at district level is delivered by nondoctor anesthetists. They require support to maintain confidence and competence, and upgraded professional registration to secure their status. To meet these needs, a distance-blended learning course was pioneered and delivered. A core course requirement was to log all clinical cases; these were logged on a new e-logbook. METHODS: Fourteen nondoctor anesthesia providers working in 12 different districts across Nepal were enrolled in the 1-year course...
May 11, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28462499/incorporation-of-lipolysis-in-monolayer-permeability-studies-of-lipid-based-oral-drug-delivery-systems
#5
Tanmoy Sadhukha, Buddhadev Layek, Swayam Prabha
Lipid-based drug delivery systems, a well-tolerated class of formulations, have been evaluated extensively to enhance the bioavailability of poorly soluble drugs. However, it has been difficult to predict the in vivo performance of lipid dosage forms based on conventional in vitro techniques such as cell monolayer permeability studies because of the complexity of the gastrointestinal processing of lipid formulations. In the current study, we explored the feasibility of coupling Caco-2 and Madin-Darby canine kidney monolayer permeability studies with lipolysis, a promising in vitro technique to evaluate lipid systems...
May 1, 2017: Drug Delivery and Translational Research
https://www.readbyqxmd.com/read/28460954/microcapsules-loaded-with-the-probiotic-lactobacillus-paracasei-bgp-1-produced-by-co-extrusion-technology-using-alginate-shellac-as-wall-material-characterization-and-evaluation-of-drying-processes
#6
Marluci P Silva, Fabricio L Tulini, Marcela M Ribas, Manfred Penning, Carmen S Fávaro-Trindade, Denis Poncelet
Microcapsules containing Lactobacillus paracasei BGP-1 were produced by co-extrusion technology using alginate and alginate-shellac blend as wall materials. Sunflower oil and coconut fat were used as vehicles to incorporate BGP-1 into the microcapsules. The microcapsules were evaluated with regard the particle size, morphology, water activity and survival of probiotics after 60days of storage at room temperature. Fluidized bed and lyophilization were used to dry the microcapsules and the effect of these processes on probiotic viability was also evaluated...
November 2016: Food Research International
https://www.readbyqxmd.com/read/28402145/the-effect-of-ph-buffer-capacity-and-ionic-strength-on-quetiapine-fumarate-release-from-matrix-tablets-prepared-using-two-different-polymeric-blends
#7
Rania Hamed, Reem AlJanabi, Suhair Sunoqrot, Aiman Abbas
The objective of this study was to investigate the effect of the different physiological parameters of the gastrointestinal (GI) fluid (pH, buffer capacity, and ionic strength) on the in vitro release of the weakly basic BCS class II drug quetiapine fumarate (QF) from two once-a-day matrix tablet formulations (F1 and F2) developed as potential generic equivalents to Seroquel(®) XR. F1 tablets were prepared using blends of high and low viscosity grades of hydroxypropyl methylcellulose (HPMC K4M and K100LV, respectively), while F2 tablets were prepared from HPMC K4M and PEGylated glyceryl behenate (Compritol(®) HD5 ATO)...
May 7, 2017: Drug Development and Industrial Pharmacy
https://www.readbyqxmd.com/read/28245257/cross-linked-%C3%AE-cyclodextrin-and-carboxymethyl-cellulose-hydrogels-for-controlled-drug-delivery-of-acyclovir
#8
Nadia Shamshad Malik, Mahmood Ahmad, Muhammad Usman Minhas
To explore the potential role of polymers in the development of drug-delivery systems, this study investigated the use of β-cyclodextrin (β-CD), carboxymethyl cellulose (CMC), acrylic acid (AA) and N' N'-methylenebis-acrylamide (MBA) in the synthesis of hydrogels for controlled drug delivery of acyclovir (ACV). Different proportions of β-CD, CMC, AA and MBA were blended with each other to fabricate hydrogels via free radical polymerization technique. Fourier transform infrared spectroscopy (FTIR) revealed successful grafting of components into the polymeric network...
2017: PloS One
https://www.readbyqxmd.com/read/28161879/effect-of-inulin-on-the-viability-of-l-plantarum-during-storage-and-in-vitro-digestion-and-on-composition-parameters-of-vegetable-fermented-juices
#9
Estefanía Valero-Cases, María José Frutos
The prebiotic effect of different concentrations of inulin (0, 1 and 2%) on the growth and survival of Lactobacillus plantarum (LP) CECT 220 in blended carrot and orange juices was investigated after 24 h of fermentation, during 30 days of storage at 4 °C and through the phases of gastrointestinal digestion after different storage periods. Microbiological and chemical determinations were also carried out in all juices. The lactic fermentation increased the shelf life of the fermented juices with inulin...
June 2017: Plant Foods for Human Nutrition
https://www.readbyqxmd.com/read/27999889/noise-optimized-virtual-monoenergetic-dual-energy-computed-tomography-optimization-of-kiloelectron-volt-settings-in-patients-with-gastrointestinal-stromal-tumors
#10
Simon S Martin, Sophia Pfeifer, Julian L Wichmann, Moritz H Albrecht, Doris Leithner, Lukas Lenga, Jan-Erik Scholtz, Thomas J Vogl, Boris Bodelle
PURPOSE: The aim of this study was to evaluate the impact of a noise-optimized virtual monoenergetic imaging (VMI+) reconstruction technique on quantitative and qualitative image analysis in patients with gastrointestinal stromal tumors (GISTs) at dual-energy computed tomography (DECT) of the abdomen. METHODS: Forty-five DECT datasets of 21 patients (14 men; 63.7 ± 9.2 years) with GISTs were reconstructed with the standard linearly blended (M_0.6) and VMI+ and traditional virtual monoenergetic (VMI) algorithm in 10-keV increments from 40 to 100 keV...
December 20, 2016: Abdominal Radiology
https://www.readbyqxmd.com/read/27818241/poly-vinyl-acetate-and-ammonio-methacrylate-copolymer-as-unconventional-polymer-blends-increase-the-mechanical-robustness-of-hpmc-matrix-tablets
#11
R Ali, A Dashevsky, R Bodmeier
The objective was to investigate poly vinyl acetate (Kollicoat(®) SR 30 D) and ammonio methacrylate copolymer (Eudragit(®) RL 30 D) blends as coatings to increase the mechanical robustness of hydroxypropyl methylcellulose (HPMC) matrix tablets. Poly vinyl acetate (Kollicoat(®) SR 30 D - KSR) was selected for its flexibility and ammonio methacrylate copolymer (Eudragit(®) RL 30 D - ERL) because of its high permeability. Films based on KSR:ERL blends were prepared by casting or spraying aqueous dispersions of these polymers and were characterized by water uptake, dry mass loss and mechanical properties...
January 10, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/27718119/successful-colonoscopic-fecal-microbiota-transplantation-for-active-ulcerative-colitis-first-report-from-india
#12
Avnish Kumar Seth, Pawan Rawal, Ruchika Bagga, Priti Jain
Forty-four-year-old male with ulcerative colitis (UC) for 11 years reported frequent relapse despite daily sulfasalazine 4 g, azathioprine 125 mg, and rectal 5-aminosalicylic acid. Repeated use of corticosteroids led to cataract. At enrollment, he was passing eight stools a day with blood with a Mayo score of 9 (3+1+3+2). Stool was negative for ova/cysts/acid fast bacilli and Clostridium difficile toxin assay. Rectal biopsy showed cryptitis, crypt abscess, and crypt distortion with no inclusion bodies, and cytomegalovirus DNA was negative...
September 2016: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
https://www.readbyqxmd.com/read/27578252/orange-pomace-fibre-increases-a-composite-scoring-of-subjective-ratings-of-hunger-and-fullness-in-healthy-adults
#13
Honglin Dong, Laura J Sargent, Yianna Chatzidiakou, Caroline Saunders, Laura Harkness, Nicolas Bordenave, Ian Rowland, Jeremy P E Spencer, Julie A Lovegrove
Dietary fibre has been shown to increase subjective satiating ratings. However data from human trials has produced mixed results, possibly due to different types of fibre which have diverse physicochemical properties and gastrointestinal transit behaviour. The aim of study 1 was to investigate whether orange juice (OJ) with 5.5 g of added orange pomace fibre (OPF) was as satiating as whole orange (WO, chopped and blended to a puree/liquid) compared with OJ. Study 2 was to evaluate the dose-dependent satiating effect of OPF delivered in an orange-flavoured beverage...
December 1, 2016: Appetite
https://www.readbyqxmd.com/read/27365987/up1306-a-botanical-composition-with-analgesic-and-anti-inflammatory-effect
#14
Mesfin Yimam, Young-Chul Lee, Ping Jiao, Mei Hong, Jeong-Bum Nam, Lidia Brownell, Eujin Hyun, Qi Jia
BACKGROUND: Pain, one of the cardinal signs of inflammation, is the most common clinical manifestations of arthritis. Conventional pain relief therapy heavily relies on the use of prescription and over the counter nonsteroidal anti-inflammatory drugs as the first line of defense where their long-term usage causes deleterious gastrointestinal and cardiovascular-related side-effects. Hence, there is an equivocal need for evidence-based safer and efficacious alternatives from natural sources to overcome the most prominent and disabling symptoms of arthritis...
July 2016: Pharmacognosy Research
https://www.readbyqxmd.com/read/27336698/infant-formula-with-partially-hydrolyzed-proteins-in-functional-gastrointestinal-disorders
#15
Yvan Vandenplas, Silvia Salvatore
UNLABELLED: Over 50% of all infants present with one or more functional gastrointestinal disorders (FGIDs) during the first months of life. The literature on the effect of partially hydrolyzed formula (pHF) in the management of FGIDs was reviewed. There is insufficient evidence to recommend pHFs in regurgitation, although one study suggests that a thickened pHF may be more effective than antiregurgitation formulas with intact protein. No randomized clinical trials on pHFs in infants with colicky symptoms have been published...
2016: Nestlé Nutrition Institute Workshop Series
https://www.readbyqxmd.com/read/27207660/can-supplementation-of-phytoestrogens-insoluble-fibers-help-the-management-of-duodenal-polyps-in-familial-adenomatous-polyposis
#16
Carlo Calabrese, Fernando Rizzello, Paolo Gionchetti, Andrea Calafiore, Nico Pagano, Luigia De Fazio, Maria Chiara Valerii, Elena Cavazza, Antonio Strillacci, Maria Cristina Comelli, Gilberto Poggioli, Massimo Campieri, Enzo Spisni
Familial adenomatous polyposis (FAP) is an autosomal dominant inherited disorder, and prophylactic colectomy has been shown to decrease the incidence of colorectal cancer (CRC). Duodenal cancer and desmoids are now the leading causes of death in FAP. We evaluate whether 3 months of oral supplementation with a patented blend of phytoestrogens and indigestible insoluble fibers (ADI) help the management of FAP patients with ileal pouch-anal anastomosis (IPAA). In a prospective open label study, we enrolled 15 FAP patients with IPAA and duodenal polyps who underwent upper gastrointestinal endoscopy at baseline and after 3 months of treatment...
2016: Carcinogenesis
https://www.readbyqxmd.com/read/27191052/in-vitro-assessment-of-potential-intestinal-absorption-of-some-phenolic-families-and-carboxylic-acids-from-commercial-instant-coffee-samples
#17
R López-Froilán, E Ramírez-Moreno, N S Podio, M L Pérez-Rodríguez, M Cámara, M V Baroni, D A Wunderlin, M C Sánchez-Mata
Coffee is one of the most consumed beverages in the world, being a source of bioactive compounds as well as flavors. Hydroxycinnamic acids, flavonols, and carboxylic acids have been studied in the samples of instant coffee commercialized in Spain. The studies about contents of food components should be complemented with either in vitro or in vivo bioaccessibility studies to know the amount of food components effectively available for functions in the human body. In this sense, a widely used in vitro model has been applied to assess the potential intestinal absorption of phenolic compounds and organic acids...
June 15, 2016: Food & Function
https://www.readbyqxmd.com/read/27051631/formulation-and-evaluation-of-atenolol-floating-bioadhesive-system-using-optimized-polymer-blends
#18
Haritha Siddam, Niranjan G Kotla, Balaji Maddiboyina, Sima Singh, Omprakash Sunnapu, Anil Kumar, Dinesh Sharma
INTRODUCTION: Oral sustained release gastro retentive dosage forms offer several advantages for drugs having absorption from the upper gastrointestinal tract to improve the bioavailability of medications which have narrow absorption window. The aim of the study was to develop a floating bioadhesive drug delivery system exhibiting a unique combination of floatation and bioadhesion to prolong the residence in the stomach using atenolol as a model drug. METHODS: Prior to compression, polymeric blend(s) were evaluated for flow properties...
April 2016: International Journal of Pharmaceutical Investigation
https://www.readbyqxmd.com/read/27034601/up1304-a-botanical-composition-containing-two-standardized-extracts-of-curcuma-longa-and-morus-alba-mitigates-pain-and-inflammation-in-adjuvant-induced-arthritic-rats
#19
Mesfin Yimam, Young-Chul Lee, Breanna Moore, Ping Jiao, Mei Hong, Jeong-Bum Nam, Mi-Ran Kim, Tae-Woo Kim, Hyun-Jin Kim, Eu-Jin Hyun, Min Chu, Lidia Brownell, Qi Jia
BACKGROUND: Though, the initial etiologies of arthritis are multifactorial, clinically, patients share pain as the prime complaints. Present day pain relief therapeutics heavily relies on the use of prescription and over the counter nonsteroidal anti-inflammatory drugs as the first line of defense where their long-term usage causes gastrointestinal and cardiovascular-related side effects. Hence, the need for evidence-based safer and efficacious alternatives from natural sources to overcome the most prominent and disabling symptoms of arthritis is an overdue...
April 2016: Pharmacognosy Research
https://www.readbyqxmd.com/read/27016492/safety-evaluation-of-ab-life-%C3%A2-lactobacillus-plantarum-cect-7527-7528-and-7529-antibiotic-resistance-and-90-day-repeated-dose-study-in-rats
#20
Pushkor Mukerji, Jason M Roper, Buffy Stahl, Amy B Smith, Frank Burns, Jessica Caverly Rae, Nicolas Yeung, Anna Lyra, Laura Svärd, Markku T Saarinen, Esa Alhoniemi, Alvin Ibarra, Arthur C Ouwehand
AB-LIFE(®) is a probiotic product consisting of equal parts of three strains of Lactobacillus plantarum (CECT 7527, 7528, and 7529) blended with inert excipients. Whole genome sequencing was performed on each of the three strains. Antibiotic resistance was evaluated by genomic mining for resistance genes, and assessment for transferability. No risk of transfer potential was identified for any antibiotic resistance genes in the three strains. AB-LIFE(®) was evaluated for potential subchronic oral toxicity in rats, with dosages of 300 and 1000 mg/kg BW/day (equivalent to 5...
June 2016: Food and Chemical Toxicology
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