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Oesophageal manometry

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https://www.readbyqxmd.com/read/28535800/comparison-of-oesophageal-function-tests-between-chinese-non-erosive-reflux-disease-and-reflux-hypersensitivity-patients
#1
Feng Gao, Yan Gao, Xue Chen, Jie Qian, Jie Zhang
BACKGROUND: By means of 24 h multi-channel intraluminal impedance and pH recording (MII/pH), patients with heartburn and normal upper gastrointestinal endoscopy findings can be classified into those with non-erosive reflux disease (NERD) and those with reflux hypersensitivity (RH). Therefore, in this study, we investigated the difference in oesophageal function tests in Chinese patients with NERD and RH. METHODS: NERD patients were selected from the digestive department, Beijing Anzhen Hospital and Beijing Chao-Yang Hospital, Capital Medical University, after upper gastrointestinal endoscope, high-resolution manometry and impedance (HRiM), and MII/pH examinations between 2014 and 2016...
May 23, 2017: BMC Gastroenterology
https://www.readbyqxmd.com/read/28447027/gastric-function-in-children-with-oesophageal-atresia-and-tracheoesophageal-fistula
#2
REVIEW
Gilles Duvoisin, Usha Krishnan
Oesophageal atresia and tracheoesophageal fistula (OA-TOF) are a multifaceted condition which affects patients throughout their lives. Even though it is one of the most common gastrointestinal malformations, most of the current studies focus on gastro-oesophageal reflux disease, anastomotic strictures, and feeding difficulties. However, there is increasing evidence that a proportion of patients with OA-TOF also have abnormal gastric function. This review aims to provide a comprehensive understanding of studies of gastric function in patients with OA-TOF...
2017: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/28346382/the-balloon-based-manometry-evaluation-of-swallowing-in-patients-with-amyotrophic-lateral-sclerosis
#3
Jerzy Tomik, Barbara Tomik, Sebastian Gajec, Piotr Ceranowicz, Małgorzata Pihut, Rafał Olszanecki, Paweł Stręk, Jacek Składzień
The aim of the study was to analyse the disturbances of the oro-pharyngeal swallowing phase of dysphagia in amyotrophic lateral sclerosis (ALS) patients with the use of specific manometric measurements and to evaluate their plausible association with the duration of the disease. Seventeen patients with ALS were evaluated with manometric examinations of the oral and pharyngeal part of the gastrointestinal tract. Tests were carried out by using the oesophageal balloon-based method with four balloon transducers located 5 cm away from each other...
March 27, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28258931/the-effects-of-paroxetine-and-amitriptyline-on-the-upper-esophageal-sphincter-ues-pressure-and-its-natural-history-in-globus-pharyngeus
#4
Wen-Cong Zhou, Lin Jia, Dong-Yun Chen, Yao Liu, Jing Liu, Shu-Man Jiang, Meng Yang, Jian Xu
BACKGROUND: Antidepressant agents have been shown to be an effective and safe treatment method for patients with globus. However, there are few clinical trials dedicated to studying the effects of antidepressant agents on the natural history and upper oesophageal sphincter (UES) pressure of treated globus patients. AIMS: To evaluate the effect of paroxetine and amitriptyline to prevent relapses in patients with globus, the simultaneous relationship between changes in UES pressure and improvement of globus symptoms were measured...
February 28, 2017: Digestive and Liver Disease
https://www.readbyqxmd.com/read/28252352/fundoplication-for-laryngopharyngeal-reflux-despite-preoperative-dysphagia
#5
G L Falk, H Van der Wall, L Burton, M G Falk, H O'Donnell, S J Vivian
INTRODUCTION Fundoplication for laryngopharyngeal disease with oesophageal dysmotility has led to mixed outcomes. In the presence of preoperative dysphagia and oesophageal dysmotility, this procedure has engendered concern in certain regards. METHODS This paper describes a consecutive series of laryngopharyngeal reflux (LPR) patients with a high frequency of dysmotility. Patients were selected for surgery with 24-hour dual channel pH monitoring, oesophageal manometry and standardised reflux scintigraphy. RESULTS Following careful patient selection, 33 patients underwent fundoplication by laparoscopy...
March 2017: Annals of the Royal College of Surgeons of England
https://www.readbyqxmd.com/read/27859421/the-learning-curve-for-interpretation-of-oesophageal-high-resolution-manometry-a-prospective-interventional-cohort-study
#6
S Gaddam, C A Reddy, S Munigala, A Patel, N Kanuri, S Almaskeen, M K Rude, A Abdalla, C P Gyawali
BACKGROUND: High-resolution manometry has become the preferred choice of oesophagologists for oesophageal motor assessment, but the learning curve among trainees remains unclear. AIM: To determine the learning curve of high-resolution manometry interpretation. METHODS: A prospective interventional cohort study was performed on 18 gastroenterology trainees, naïve to high-resolution manometry (median age 32 ± 4.0 years, 44.4% female). An intake questionnaire and a 1-h standardised didactic session were performed at baseline...
January 2017: Alimentary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/27663505/the-gastric-acid-pocket-is-attenuated-in-h-pylori-infected-subjects
#7
David R Mitchell, Mohammad H Derakhshan, Angela A Wirz, Clare Orange, Stuart A Ballantyne, James J Going, Kenneth E L McColl
OBJECTIVE: Gastric acid secretory capacity in different anatomical regions, including the postprandial acid pocket, was assessed in Helicobacter pylori positive and negative volunteers in a Western population. DESIGN: We studied 31 H. pylori positive and 28 H. pylori negative volunteers, matched for age, gender and body mass index. Jumbo biopsies were taken at 11 predetermined locations from the gastro-oesophageal junction and stomach. Combined high-resolution pH metry (12 sensors) and manometry (36 sensors) was performed for 20 min fasted and 90 min postprandially...
September 23, 2016: Gut
https://www.readbyqxmd.com/read/27612220/-long-term-hr-manometry-of-the-esophagus-first-findings-in%C3%A2-clinical-use
#8
A Jell, D Wilhelm, D Ostler, H Feußner, N Hüser
Diagnosis of oesophageal motility disorders has been well established for many years now, although circadian gastrointestinal motility is still purely understood. So far, high-resolution manometry (HRM) is only available for short-term measurement in clinical practice to evaluate simultaneous pressure conditions throughout the esophagus. Thus, only a very limited period of time can be investigated. There is evidence that disorders in esophageal motility can cause severe discomfort and symptoms even though they only tend to occur spontaneously...
September 2016: Zeitschrift Für Gastroenterologie
https://www.readbyqxmd.com/read/27608870/salt-and-pepper-pigmentation-skin-manifestation-of-systemic-sclerosis
#9
D Vijayaraju, G Prakash, T Yoganandh, S R Subramanian, S Ramkumar
A 50 year old male presented with progressive difficulty in swallowing both liquid and solid food with no history of Raynaud's phenomenon. A general examination revealed skin changes in the form of thickening, hyperpigmentation and tightening of skin of fingers, hand, forearm and legs. The patient had painless skin induration over the legs, forearm and hand. Salt and pepper pigmentation was seen on the upper back (Figure 1a), over mastoid process (Figure 1b) and the concha of pinna (Figure 1c). Anti-Scl 70 was positive...
September 2015: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/27585083/cricopharyngeal-function-or-dysfunction-what-s-the-deal
#10
Jacqui E Allen
PURPOSE OF REVIEW: The purpose of the review is to examine current research focused on upper oesophageal sphincter (UES) and cricopharyngeus muscle function, and how better understanding UES physiology will translate to improved management. RECENT FINDINGS: Although much is known about UES function, new information describing the dynamics of the UES and cricopharyngeus is being identified through manometry, combined fluoromanometry, and anatomic study. Response of the UES to injury, reflux, and surgical interventions is reported...
December 2016: Current Opinion in Otolaryngology & Head and Neck Surgery
https://www.readbyqxmd.com/read/27576498/motility-characteristics-in-the-transition-zone-in-gastroesophageal-reflux-disease-gord-patients
#11
Yu-Wen Li, Chen-Xi Xie, Kai-Ming Wu, Min-Hu Chen, Ying-Lian Xiao
BACKGROUND: Defects in distal oesophageal peristalsis was thought to be an indication of incomplete bolus transit (BT). However, the role of transition zone (TZ) defects in the BT in gastroesophageal reflux disease (GORD) patients needs clarification. The aim of this study was to assess the TZ defects in GORD patients and to explore the relationship between TZ defects and BT. METHODS: One hundred and two patients with reflux symptoms and 20 healthy adults were included in the study...
August 30, 2016: BMC Gastroenterology
https://www.readbyqxmd.com/read/27536373/oesophageal-motility-disorders-in-infected-immigrants-with-chagas-disease-in-a-non-endemic-european-area
#12
Sílvia Roure, Lluís Valerio, Xavier Vallès, Betty Morales, M Immaculada Garcia-Diaz, M Luisa Pedro-Botet, Jordi Serra
BACKGROUND: Immigration-related new diseases pose a growing challenge for healthcare services in receptor countries. Following Latin American migration, Chagas disease has inevitably appeared in Europe. AIM: To determine the prevalence and characteristics of oesophageal motility disorders in immigrants infected with Trypanosoma cruzi, using high resolution oesophageal manometry (HREM). METHODS: In all newly-diagnosed cases with chronic Chagas infection referring upper digestive symptoms, a protocolized clinical evaluation and complementary tests including barium oesophagogram and HREM were carried out...
August 2016: United European Gastroenterology Journal
https://www.readbyqxmd.com/read/27453169/prevalence-and-characteristics-of-acid-gastro-oesophageal-reflux-disease-in-jackhammer-oesophagus
#13
Anne-Laure Mallet, Alain Ropert, Guillaume Bouguen, Laurent Siproudhis, Dominique Boutroux, Jean-François Bretagne, Charlène Brochard
BACKGROUND: An association between acid gastro-oesophageal reflux disease (GERD) and Jackhammer oesophagus has been suggested. AIM: To assess the prevalence and characteristics of acid-GERD in Jackhammer oesophagus and the efficacy of proton pump inhibitors. METHODS: Data and outcomes of patients with Jackhammer oesophagus were assessed. Two groups were compared: (i) GERD, defined by endoscopic oesophagitis or by an increase in acid exposure time or by an acid-hypersensitive oesophagus and (ii) non-GERD defined by normal oesophageal acid exposure without acid-hypersensitive oesophagus...
October 2016: Digestive and Liver Disease
https://www.readbyqxmd.com/read/27385135/early-myotomy-and-fundoplication-in-achalasia-in-childhood-a-single-centre-experience-for-22-years
#14
Basak Erginel, Feryal Gun Soysal, Erbug Keskin, Alaaddin Celik, Tansu Salman
Introduction The aim of this study was to review a single institution's experience with surgical interventions in children with achalasia and to determine treatment strategies for this rare disorder. Patients and methods This study is a retrospective analysis of 22 cases of childhood achalasia from 1991 to 2013. The patients were evaluated in terms of age, symptoms, interventions, intraoperative complications, and recurrent dysphagia. Results There were 13 boys and nine girls (7 months to 17 years old). The clinical symptoms were vomiting (68%), dysphagia (36%), wheezing (18%), coughing (13%), and weight-loss (13%)...
February 2016: Acta Chirurgica Belgica
https://www.readbyqxmd.com/read/27373195/the-gerdq-questionnaire-and-high-resolution-manometry-support-the-hypothesis-that-proton-pump-inhibitor-responsive-oesophageal-eosinophilia-is-a-gerd-related-phenomenon
#15
E V Savarino, S Tolone, O Bartolo, C de Cassan, R Caccaro, F Galeazzi, L Nicoletti, R Salvador, M Martinato, M Costantini, V Savarino
BACKGROUND: Little is known about the relationship between proton pump inhibitor-responsive oesophageal eosinophilia (PPI-REE), eosinophilic esophagitis (EoE) and gastro-oesophageal reflux disease (GERD). AIM: To compare high resolution manometry features and symptom profiles of patients with EoE, PPI-REE and GERD. METHODS: Consecutive patients diagnosed with EoE or PPI-REE according to international criteria (presence of at least one typical symptom of oesophageal dysfunction; at least 15 eosinophils per high-power field at mid/proximal oesophagus, persistence or resolution of eosinophils after an 8-week PPI trial), and a group of patients with proven GERD and oesophageal eosinophilia, prospectively completed the GerdQ questionnaire and underwent high resolution manometry...
September 2016: Alimentary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/27251833/laparoscopic-diverticulectomy-with-the-aid-of-intraoperative-gastrointestinal-endoscopy-to-treat-epiphrenic-diverticulum
#16
Lei Yu, Ji-Xiang Wu, Xiao-Hong Chen, Yun-Feng Zhang, Ji Ke
OBJECTIVE: Most researchers believe that the presence of large epiphrenic diverticulum (ED) with severe symptoms should lead to the consideration of surgical options. The choice of minimally invasive techniques and whether Heller myotomy with antireflux fundoplication should be employed after diverticulectomy became points of debate. The aim of this study was to describe how to perform laparoscopic transhiatal diverticulectomy (LTD) and oesophagomyotomy with the aid of intraoperative gastrointestinal (GI) endoscopy and how to investigate whether the oesophagomyotomy should be performed routinely after LTD...
October 2016: Journal of Minimal Access Surgery
https://www.readbyqxmd.com/read/27196581/hiatus-hernia-in-healthy-volunteers-is-associated-with-intrasphincteric-reflux-and-cardiac-mucosal-lengthening-without-traditional-reflux
#17
Elaine V Robertson, Mohammad H Derakhshan, Angela A Wirz, David R Mitchell, James J Going, Andrew W Kelman, Stuart A Ballantyne, Kenneth E L McColl
BACKGROUND AND AIMS: Hiatus hernia (HH) is a key mediator of gastro-oesophageal reflux disease but little is known about its significance in the general population. We studied the structure and function of the gastro-oesophageal junction in healthy volunteers with and without HH. METHODS: We compared 15 volunteers with HH, detected by endoscopy or MRI scan, but without gastro-oesophageal reflux disease with 15 controls matched for age, gender and body weight. Jumbo biopsies were taken across the squamocolumnar junction (SCJ)...
July 2017: Gut
https://www.readbyqxmd.com/read/27174454/jackhammer-oesophagus-in-a-case-of-linitis-plastica
#18
Naueen Akbar Chaudhry, Kamran Zahid, Roxana Coman, Qing Zhang
A 52-year-old Caucasian woman presented with progressive nausea and vomiting, weight loss, and burning epigastric and chest pain. Initial oesophagogastroduodenoscopy (OGD) with biopsies demonstrated gastritis in absence of Helicobacter pylori A gastric emptying study, CT scan with pancreatic protocol and a colonoscopy revealed no concerning findings. Calcium channel blockers and proton pump inhibitors offered little improvement. A high-resolution oesophageal impedance manometry was performed, which was significant for jackhammer oesophagus with maximum distal contractile index 11 052 mm Hg-s-cm...
May 12, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27068836/in-vivo-oesophageal-regeneration-in-a-human-being-by-use-of-a-non-biological-scaffold-and-extracellular-matrix
#19
Kulwinder S Dua, Walter J Hogan, Abdul A Aadam, Mario Gasparri
BACKGROUND: Tissue-engineered extracellular matrix populated with autologous pluripotent cells can result in de-novo organogenesis, but the technique is complex, not widely available, and has not yet been used to repair large oesophageal defects in human beings. We aimed to use readily available stents and extracellular matrix to regenerate the oesophagus in vivo in a human being to re-establish swallowing function. METHODS: In a patient aged 24 years, we endoscopically placed a readily available, fully covered, self-expanding, metal stent (diameter 18 mm, length 120 mm) to bridge a 5 cm full-thickness oesophageal segment destroyed by a mediastinal abscess and leading to direct communication between the hypopharynx and the mediastinum...
July 2, 2016: Lancet
https://www.readbyqxmd.com/read/26960826/oesophageal-manometry-in-experimental-pigs-methods-and-initial-experience
#20
Ilja Tachecí, Věra Radochová, Jaroslav Květina, Stanislav Rejchrt, Marcela Kopáčová, Jan Bureš
The aim of this study project was to prepare our own method of porcine oesophageal manometry. Ten mature experimental pigs entered the study. Conventional water-perfused system was decided for manometry. Porcine resting and relaxed pressures of the lower oesophageal sphincter are fully comparable with healthy human subjects. Evocable swallowing is doable and oesophageal peristalsis is quantifiable. Basic manometric parameters were different in male and female animals. Oesophageal manometry in experimental pigs is feasible...
2015: Acta Medica (Hradec Králové)
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