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https://www.readbyqxmd.com/read/27800586/liquid-antiadhesive-agents-for-intraperitoneal-hernia-repair-procedures-artiss-%C3%A2-compared-to-coseal-%C3%A2-and-adept-%C3%A2-in-an-ipom-rat-model
#1
Simone Gruber-Blum, R H Fortelny, C Keibl, J Brand, M Lechner, H Redl, A H Petter-Puchner
BACKGROUND: Adhesion formation remains an important issue in hernia surgery. Liquid agents were developed for easy and versatile application, especially in laparoscopy. The aim of this study was to compare the antiadhesive effect of fibrin sealant (FS, Artiss(®)), Icodextrin (ID, Adept(®)) and Polyethylene glycol (PEG, CoSeal(®)) alone and in combination and to evaluate the resulting effect on tissue integration of the mesh. METHODS: A total of 56 Sprague-Dawley rats were operated in open IPOM technique...
October 31, 2016: Surgical Endoscopy
https://www.readbyqxmd.com/read/26816671/reducing-morbidity-with-surgical-adhesives-following-inguinal-lymph-node-dissections-for-the-treatment-of-malignant-skin-tumors
#2
Peter L Stollwerck, Dominik Schlarb, Nicole Münstermann, Sebastian Stenske, Christoph Kruess, Gerhard Brodner, Björn Dirk Krapohl, Albrecht F Krause-Bergmann
BACKGROUND: Inguinal lymph node dissection (ILND) is associated with a high rate of morbidity. To evaluate the clinical benefit of surgical adhesives to reduce complications in patients undergoing ILND, we compared the use of TissuGlu(®) Surgical Adhesive and ARTISS(®) fibrin sealant with a control population. MATERIAL AND METHODS: We conducted a retrospective analysis of patients undergoing ILND for metastatic malignant skin tumors at one hospital, Fachklinik Hornheide (Münster, Germany), from January 2011 through September 2013, assessing 137 patients with a total of 142 procedures...
2016: GMS Interdisciplinary Plastic and Reconstructive Surgery DGPW
https://www.readbyqxmd.com/read/25462702/the-effects-of-low-thrombin-fibrin-sealant-on-wound-serous-drainage-seroma-formation-and-length-of-postoperative-stay-in-patients-undergoing-axillary-node-dissection-for-breast-cancer-a-randomized-controlled-trial
#3
RANDOMIZED CONTROLLED TRIAL
Raffaella Benevento, Antonio Santoriello, Gianluca Pellino, Guido Sciaudone, Giuseppe Candilio, G Serena De Fatico, Francesco Selvaggi, Silvestro Canonico
BACKGROUND: Breast cancer surgery with axillary lymphadenectomy may be associated with prolonged stay of the drain in the axilla due to high wound output, which may require further treatments and prolong the length of stay, impairing quality of life. No definitive data are available concerning how to prevent this complication. Our aim was to assess the efficacy of a new low-thrombin fibrin glue in reducing the serous output from the axillary surgical wound in patients undergoing axillary node dissection for breast cancer, and its long-term effects on lymphedema...
November 2014: International Journal of Surgery
https://www.readbyqxmd.com/read/25339155/the-use-of-a-fibrin-glue-with-a-low-concentration-of-thrombin-decreases-seroma-formation-in-postbariatric-patients-undergoing-circular-abdominoplasty
#4
RANDOMIZED CONTROLLED TRIAL
Vincenzo Pilone, Antonio Vitiello, Ciro Borriello, Stefano Gargiulo, Pietro Forestieri
BACKGROUND: The serum collection under the abdominal flap is the most common complication after a lipo-abdominoplasty. The frequency of seroma increases further among obese patients, who have achieved massive weight loss after bariatric surgery. The purpose of this study is to demonstrate the effectiveness of fibrin glues with a low concentration of thrombin in reducing seroma formation after a lipo-abdominoplasty. METHODS: Thirty patients, that had achieved a significant weight loss after an intervention of laparoscopic adjustable gastric banding (LAGB), underwent a circular lipo-abdominoplasty at our bariatric surgery department...
February 2015: Obesity Surgery
https://www.readbyqxmd.com/read/23806736/the-effect-of-%C3%AE-cyclodextrin-on-postprandial-lipid-and-glycemic-responses-to-a-fat-containing-meal
#5
RANDOMIZED CONTROLLED TRIAL
Patricia A Jarosz, Evan Fletcher, Eman Elserafy, Joseph D Artiss, K-L Catherine Jen
OBJECTIVE: α-Cyclodextrin (α-CD), a soluble dietary fiber derived from corn, marketed under the trade name FBCx®, has the potential to help individuals manage their weight and improve their lipid profiles. Initial studies in healthy overweight and/or obese diabetic individuals found that, in those consuming a normal to high fat diet over a 4 or 12 week period, α-CD use was associated with weight loss or maintenance and a reduction in triglyceride (TG) and cholesterol levels in hyperlipidemic individuals...
October 2013: Metabolism: Clinical and Experimental
https://www.readbyqxmd.com/read/23578196/use-of-fibrin-sealants-in-cardiovascular-surgery-a-systematic-review
#6
REVIEW
John A Rousou
BACKGROUND: Fibrin sealants are used for hemostasis and tissue adherence. AIM OF STUDY: This systematic review summarizes published clinical data for fibrin sealant use in cardiovascular surgery. METHODS: A literature search for the following terms was conducted using PubMed and EMBASE: (TISSEEL or Tissucol or Beriplast P or Evicel or Quixil or Crosseal or Reliseal or Fibringluraas or Bolheal or Tachosil or Vivostat or Vitagel or Artiss or "fibrin glue" or "fibrin sealant" or "fibrin tissue adhesive") and (cardiac or cardiovascular or vascular or heart or coronary or surgery)...
May 2013: Journal of Cardiac Surgery
https://www.readbyqxmd.com/read/23566443/transporous-hernia-mesh-fixation-with-fibrin-sealant-in-an-in-vitro-model-of-spray-application
#7
COMPARATIVE STUDY
Julian Brand, Simone Gruber-Blum, Kerstin Gruber, René H Fortelny, Heinz Redl, Alexander H Petter-Puchner
BACKGROUND: The spray application of fibrin sealant (FS) is widely used for atraumatic mesh fixation in open and laparoscopic hernia surgery. Studies focusing on the optimization of sealant distribution are rare. This study elucidates the impact of spray distance and pressure, the thrombin concentration of the FS, as well as the mesh design on the spray process and the resulting sealant distribution. Furthermore, the effect of interrupting the spray process on sealant distribution was investigated...
August 2013: Journal of Surgical Research
https://www.readbyqxmd.com/read/23563904/randomized-controlled-phase-3-study-to-evaluate-the-safety-and-efficacy-of-fibrin-sealant-vh-s-d-4-s-apr-artiss-to-improve-tissue-adherence-in-subjects-undergoing-rhytidectomy
#8
RANDOMIZED CONTROLLED TRIAL
T Roderick Hester, James R Shire, Davis B Nguyen, Zachary E Gerut, Achih H Chen, Jason Diamond, Julian C Desmond, Laura Silvati-Fidell, Steve Zvi Abrams, Rod J Rohrich
BACKGROUND: Suction drains are commonly placed after rhytidectomy to avoid seroma formation that may result from dead spaces between skin layers. Fibrin sealants promote tissue adherence by crosslinking with extracellular matrix proteins, which may reduce the dead space under skin flaps. OBJECTIVES: The authors evaluate the safety and efficacy of the fibrin sealant (FS) VH S/D 4 s-apr (Artiss; Baxter Healthcare Corp, Deerfield, Illinois), added to standard-of-care (SoC) treatment, in improving flap adherence and reducing dead space in patients undergoing rhytidectomy...
May 2013: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/23515377/exploratory-randomized-controlled-phase-2-study-to-evaluate-the-safety-and-efficacy-of-adjuvant-fibrin-sealant-vh-s-d-4-s-apr-artiss-in-patients-undergoing-rhytidectomy
#9
RANDOMIZED CONTROLLED TRIAL
T Roderick Hester, Zachary E Gerut, James R Shire, Davis B Nguyen, Achih H Chen, Jason Diamond, Julian C Desmond, Laura Silvati-Fidell, Steve Zvi Abrams
BACKGROUND: Suction drains are commonly placed after rhytidectomy surgery to avoid seroma formation that may result from dead spaces between skin layers. Fibrin sealants promote tissue adherence by cross-linking with extracellular matrix proteins, which may reduce the dead space under skin flaps. OBJECTIVES: The authors evaluate the safety and preliminary efficacy of the fibrin sealant (FS) VH S/D 4 s-apr (ARTISS; Baxter Healthcare Corp, Deerfield, Illinois), added to standard-of-care (SoC) treatment, on tissue plane adherence and local hemostasis in rhytidectomy patients...
March 2013: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/21995495/mephedrone-4-methylmethcathinone-meow-acute-behavioural-effects-and-distribution-of-fos-expression-in-adolescent-rats
#10
Craig P Motbey, Glenn E Hunt, Michael T Bowen, Suzanne Artiss, Iain S McGregor
Mephedrone (4-methylmethcathinone) is a novel recreational drug that has rapidly increased in popularity in recent years. Users report mephedrone as having the stimulant-like qualities of methamphetamine and cocaine, combined with the prosocial, entactogenic effects of 3,4-methylenedioxymethamphetamine (MDMA). Anecdotal and case study reports indicate that mephedrone may have the potential to engender compulsive patterns of use as well as toxicity in overdose. However, there have been almost no neuropharmacological investigations of the drug up to this point...
March 2012: Addiction Biology
https://www.readbyqxmd.com/read/21607571/histologic-evaluation-of-absorbable-and-non-absorbable-barrier-coated-mesh-secured-to-the-peritoneum-with-fibrin-sealant-in-a-new-zealand-white-rabbit-model
#11
E D Jenkins, L Melman, S Desai, C R Deeken, S C Greco, M M Frisella, B D Matthews
PURPOSE: The purpose of this study is to evaluate the histologic response to fibrin sealant (FS) as an alternative fixation method for laparoscopic ventral hernia repair. METHODS: One non-absorbable barrier mesh (Composix™) and three absorbable barrier meshes (Sepramesh™, Proceed™, and Parietex™ Composite) were used for the study, with uncoated macroporous polypropylene mesh (ProLite Ultra™) as the control. Three methods of fixation were used: #0-polypropylene suture + FS (ARTISS™, Baxter Healthcare Corp...
December 2011: Hernia: the Journal of Hernias and Abdominal Wall Surgery
https://www.readbyqxmd.com/read/21127475/the-beneficial-effects-of-%C3%AE-cyclodextrin-on-blood-lipids-and-weight-loss-in-healthy-humans
#12
RANDOMIZED CONTROLLED TRIAL
Kevin B Comerford, Joseph D Artiss, K L Catherine Jen, Sidika E Karakas
α-Cyclodextrin (α-CD) is a soluble fiber derived from corn. It has previously been reported that early intervention with Mirafit fbcx, a trademarked name for α-CD, has beneficial effects on weight management in obese individuals with type 2 diabetes, and that it preferentially reduces blood levels of saturated and trans fats in the LDL receptor knockout mice. The current investigation involves overweight but not obese nondiabetic individuals and was intended to confirm the effects of α-CD on both weight management and improving blood lipid levels...
June 2011: Obesity
https://www.readbyqxmd.com/read/20817641/evaluation-of-acute-fixation-strength-for-mechanical-tacking-devices-and-fibrin-sealant-versus-polypropylene-suture-for-laparoscopic-ventral-hernia-repair
#13
Lora Melman, Eric D Jenkins, Corey R Deeken, Michael D Brodt, Shaun R Brown, L Michael Brunt, J Christopher Eagon, Margaret Frisella, Brent D Matthews
BACKGROUND: The purpose of this comparative study is to evaluate the acute fixation strength of mechanical tacking devices and fibrin sealant against polypropylene suture for laparoscopic ventral hernia repair. METHODS: Three metallic mechanical tacking devices (ProTack, Salute, EndoANCHOR), 4 absorbable tacking devices (AbsorbaTack, PermaSorb, I-Clip, and SorbaFix), and 2 types of fibrin sealant (Tisseel, Artiss) were compared with 0-polypropylene suture. Three constructs from each device or an amount of sealant sufficient to cover a 3 × 3 cm(2) area were used to affix a 4 × 3 cm piece of absorbable barrier-coated mesh (Proceed, Ethicon, Inc) to the peritoneal surface of porcine abdominal wall...
December 2010: Surgical Innovation
https://www.readbyqxmd.com/read/20652323/evaluation-of-intraperitoneal-placement-of-absorbable-and-nonabsorbable-barrier-coated-mesh-secured-with-fibrin-sealant-in-a-new-zealand-white-rabbit-model
#14
COMPARATIVE STUDY
Eric D Jenkins, Lora Melman, Salil Desai, Shaun R Brown, Margaret M Frisella, Corey R Deeken, Brent D Matthews
BACKGROUND: This study aimed to evaluate the acute and chronic fixation strength of fibrin sealant (FS) as an alternative method of fixation for laparoscopic ventral hernia repair (LVHR). METHODS: Representative mesh types for LVHR included one nonabsorbable barrier mesh (Composix) and three absorbable barrier meshes (Sepramesh, Proceed, and Parietex composite). Macroporous polypropylene mesh (Prolite Ultra) served as the control mesh. Three methods of fixation were used, namely, 0-polypropylene suture+FS (ARTISS 4 IU), FS alone (ARTISS), and tacks alone, to secure 3×4-cm pieces of mesh (10 of each combination) to the peritoneal surface of New Zealand white rabbit abdominal wall...
February 2011: Surgical Endoscopy
https://www.readbyqxmd.com/read/20512511/a-comparison-of-a-bovine-albumin-glutaraldehyde-glue-versus-fibrin-sealant-for-hernia-mesh-fixation-in-experimental-onlay-and-ipom-repair-in-rats
#15
COMPARATIVE STUDY
S Gruber-Blum, A H Petter-Puchner, K Mika, J Brand, H Redl, W Ohlinger, T Benesch, R H Fortelny
BACKGROUND: Research in hernia repair has targeted new atraumatic mesh fixation to reduce major complications such as chronic pain and adhesion formation. The efficacy and safety of two surgical adhesives, viz. Artiss® (FS, fibrin sealant containing 4 IU thrombin) and Bioglue® (AGG, bovine serum albumin/glutaraldehyde glue), were evaluated in this study. Primary study endpoints were tissue integration, dislocation, and adhesion formation. Foreign-body reaction formed the secondary study endpoint...
December 2010: Surgical Endoscopy
https://www.readbyqxmd.com/read/20454989/evaluation-of-acute-fixation-strength-of-absorbable-and-nonabsorbable-barrier-coated-mesh-secured-with-fibrin-sealant
#16
COMPARATIVE STUDY
E D Jenkins, L Melman, M M Frisella, C R Deeken, B D Matthews
INTRODUCTION: The purpose of this study was to evaluate the acute fixation strength of fibrin sealant as an alternative fixation method for laparoscopic ventral hernia repair (LVHR) when utilized with absorbable and nonabsorbable barrier meshes. METHODS: Representative mesh types for LVHR included one nonabsorbable barrier mesh (Bard Composix) and three absorbable barrier meshes (Sepramesh, Proceed, and Parietex Composite Mesh). Macroporous polypropylene mesh (Prolite Ultra) served as a control...
October 2010: Hernia: the Journal of Hernias and Abdominal Wall Surgery
https://www.readbyqxmd.com/read/20446501/the-combat-soldier
#17
Kenneth L Artiss
The Gulf War illness (GWI) problem is seen as a postwar syndrome related to veteran discontent rather than as a new phenomenon. It is here proposed that application of social psychiatric thinking and workers' compensation experience can help in understanding the problem. Social psychiatry has been neglected in the training of so many psychiatrists that many of them fail to understand the Army as a community and to recognize that a community's parts may develop symptom neuroses. Most psychiatrists, however, do know that a symptom neurosis will not disappear until it no longer serves its purposes...
April 2010: Military Medicine
https://www.readbyqxmd.com/read/19561795/pharmaceutical-approval-update
#18
Marvin M Goldenberg
Topics include bendamustine (Treanda) for chronic lymphocytic leukemia, hepatitis B immune globulin (HepaGam B) to prevent hepatitis B infection following liver transplantation, and a fibrin sealant (Artiss) used in skin graft surgery for burn patients.
May 2008: P & T: a Peer-reviewed Journal for Formulary Management
https://www.readbyqxmd.com/read/18640380/dietary-alpha-cyclodextrin-lowers-low-density-lipoprotein-cholesterol-and-alters-plasma-fatty-acid-profile-in-low-density-lipoprotein-receptor-knockout-mice-on-a-high-fat-diet
#19
Elke Maria Wagner, Kai-Lin Catherine Jen, Joseph Donald Artiss, Alan Thomas Remaley
High dietary intake of saturated fat and cholesterol, and elevated low-density lipoprotein cholesterol levels are some of the modifiable risk factors for cardiovascular disease. Alpha-cyclodextrin (a-CD) when given orally has been shown in rats to increase fecal saturated fat excretion and to reduce blood total cholesterol levels in obese hypertriglyceridemic subjects with type 2 diabetes mellitus. In this study, the effects of dietary a-CD on lipid metabolism in low-density lipoprotein receptor knockout mice were investigated...
August 2008: Metabolism: Clinical and Experimental
https://www.readbyqxmd.com/read/18354285/efficacy-and-safety-of-a-fibrin-sealant-for-adherence-of-autologous-skin-grafts-to-burn-wounds-results-of-a-phase-3-clinical-study
#20
RANDOMIZED CONTROLLED TRIAL
Kevin Foster, David Greenhalgh, Richard L Gamelli, David Mozingo, Nicole Gibran, Michael Neumeister, Steven Zvi Abrams, Edith Hantak, Lisa Grubbs, Bettina Ploder, Neil Schofield, Louis H Riina et al.
The objective of this phase 3, multicentered, prospective, randomized, evaluator-blinded, clinical study was to compare skin graft adherence utilizing a fibrin sealant containing 4 IU/ml thrombin (FS 4IU VH S/D [FS 4IU VH S/D will be marketed under the trade name ARTISS upon licensure in the United States]) to graft adherence utilizing staples in burn patients requiring wound excision and skin grafting. FS 4IU VH S/D was compared with staples in 138 patients. Patients had burn wounds measuring < or =40% of total body surface area with two comparable test sites measuring between 1 and 4% total body surface area each...
March 2008: Journal of Burn Care & Research: Official Publication of the American Burn Association
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