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https://www.readbyqxmd.com/read/28203179/malignant-phyllodes-tumor-presenting-in-bone-brain-lungs-and-lymph-nodes
#1
Eric D Johnson, Evin Gulbahce, Joseph McNally, Saundra S Buys
INTRODUCTION: Phyllodes tumors (PTs) are rare fibroepithelial tumors of the breast which are classified as benign, borderline, or malignant. Malignant PTs account for <1% of malignant breast tumors, and borderline tumors have potential to progress to malignant tumors. Metastatic recurrences are most commonly documented in bone and lungs. We report an extremely rare presentation of recurrent malignant PTs involving the brain, lung, lymph nodes, and bone. CASE: A 66-year-old female presented with a large breast mass...
September 2016: Case Reports in Oncology
https://www.readbyqxmd.com/read/28193782/mitochondrial-mass-and-activity-as-a-function-of-body-composition-in-individuals-with-spinal-cord-injury
#2
Laura C O'Brien, Rodney C Wade, Liron Segal, Qun Chen, Jeannie Savas, Edward J Lesnefsky, Ashraf S Gorgey
Spinal cord injury (SCI) is accompanied by deterioration in body composition and severe muscle atrophy. These changes put individuals at risk for insulin resistance, type II diabetes, and cardiovascular disease. To determine the relationships between skeletal muscle mitochondrial mass, activity, and body composition, 22 men with motor complete SCI were studied. Body composition assessment was performed using dual-energy X-ray absorptiometry and magnetic resonance imaging. Skeletal muscle biopsies were obtained from the vastus lateralis muscle to measure citrate synthase (CS) and complex III (CIII) activity...
February 2017: Physiological Reports
https://www.readbyqxmd.com/read/28186470/image-guidance-based-on-mri-for-spinal-interstitial-laser-thermotherapy-technical-aspects-and-accuracy
#3
Claudio E Tatsui, Clarissa N G Nascimento, Dima Suki, Behrang Amini, Jing Li, Amol J Ghia, Jonathan G Thomas, R Jason Stafford, Laurence D Rhines, Juan P Cata, Ashok J Kumar, Ganesh Rao
OBJECTIVE Image guidance for spinal procedures is based on 3D-fluoroscopy or CT, which provide poor visualization of soft tissues, including the spinal cord. To overcome this limitation, the authors developed a method to register intraoperative MRI (iMRI) of the spine into a neuronavigation system, allowing excellent visualization of the spinal cord. This novel technique improved the accuracy in the deployment of laser interstitial thermal therapy probes for the treatment of metastatic spinal cord compression...
February 10, 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/28184002/renal-cell-carcinoma-metastasis-involving-vertebral-hemangioma-dual-percutaneous-treatment-by-navigational-bipolar-radiofrequency-ablation-and-high-viscosity-cement-vertebroplasty
#4
Jean-Baptiste Zerlauth, Reto Meuli, Vincent Dunet
The case of a 70-year-old woman with progressive renal cell carcinoma (RCC) metastatic invasion of a L3 vertebral hemangioma treated by dual percutaneous radiofrequency ablation (RFA) and vertebroplasty is reported. The patient was surgically treated for RCC in 2001. Chemotherapy and immunotherapy were introduced in 2013 for ovarian, bladder and cerebral metastatic disease. An asymptomatic L3 benign hemangioma was noticed at this time. One-year CT and MRI follow-up studies demonstrated a nodular isolated soft tissue lesion involving the anterior edge of the hemangioma...
February 9, 2017: Journal of Neurointerventional Surgery
https://www.readbyqxmd.com/read/28181826/a-new-method-for-the-prevention-of-skin-laceration-during-vacuum-assisted-breast-biopsy
#5
Juan D Berna, Florentina Guzmán-Aroca, Juan de Dios Berná-Mestre, Dolores Hernández-Gómez
OBJECTIVE: To describe a new technique to prevent skin laceration during ultrasound-guided vacuum-assisted breast biopsy (VABB) with the insertion of a spinal needle between the mass and the skin. METHODS: The study includes 118 patients with 118 BI-RADS 3 masses located very close to the skin or areola, which were excised using the Mammotome system with a spinal needle inserted just above the site of insertion of the probe. RESULTS: The mean distance between the most superficial portion of the mass to the under surface of the overlying skin was 1...
February 9, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28180052/primary-spinal-epidural-lymphoma-as-a-cause-of-spontaneous-spinal-anterior-syndrome-a-case-report-and-literature-review
#6
M E Córdoba-Mosqueda, J R Guerra-Mora, M C Sánchez-Silva, R M Vicuña-González, A Ibarra-de la Torre
Background Primary spinal epidural lymphoma (PSEL) is one of the rarest categories of tumors. Spinal cord compression is an uncommon primary manifestation and requires to be treated with surgery for the purpose of diagnosis and decompression. Case Presentation A 45-year-old man presented with a new onset thoracic pain and progress to an anterior spinal syndrome with hypoesthesia and loss of thermalgesia. Magnetic resonance image showed a paravertebral mass that produces medullary compression at T3. The patient was taken up to surgery, where the pathology examination showed a diffuse large B-cell lymphoma...
January 2017: Journal of Neurological Surgery Reports
https://www.readbyqxmd.com/read/28179707/cervical-chordoma-involving-c3-c4-a-case-report
#7
Muhammad Imran, Atiq Ahmed Khan, Syed Muneeb Younus
Chordoma is a rare, indolent but locally invasive, osteolytic, slow growing, low grade, primary bone malignancy, derived from the embryonic remnants of the notochord. It is a midline tumour and it predominantly emerges from the axial skeleton. The most commonly observed location of a chordoma is in the sacrococcygeal region ( 50 to 55% ) followed by the cranio occipital region ( 25 to 30% )We present a case of a 30 years old lady who came to us with complaints of difficulty in walking and inability to hold objects in both hands...
December 2016: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28173721/rosai-dorfman-disease-of-the-subdural-spine-with-a-long-segment-lesion-a-case-report-and-literature-review
#8
Ji Tu, Wen-Tian Li, Cao Yang
Rosai-Dorfman disease (RDD) or sinus histiocytosis with massive lymphadenopathy is a rare benign disorder usually characterized by massive painless cervical lymphadenopathy and systemic manifestations. Extranodal involvement, especially spinal involvement, is extremely rare. We report a 41-year-old man who presented with only intermittent dorsodynia. His condition was diagnosed as non-specific inflammatory disease on the basis of preoperative puncture biopsy results. We performed total surgical resection. Histopathological findings showed distinctive emperipolesis and immunohistochemistry results were positive for cluster of differentiation CD68 and S100 and negative for CD1a...
January 1, 2017: Journal of International Medical Research
https://www.readbyqxmd.com/read/28167963/physicians-perspectives-on-the-diagnosis-and-treatment-of-chronic-nonbacterial-osteomyelitis
#9
Yongdong Zhao, Fatma Dedeoglu, Polly J Ferguson, Sivia K Lapidus, Ronald M Laxer, Miranda C Bradford, Suzanne C Li
Background/Purpose. Understanding the practices of pediatric rheumatologists in diagnosing and treating chronic nonbacterial osteomyelitis (CNO) can provide important information to guide the development of consensus treatment plans. The objectives of this study were to determine physicians' approaches to (1) diagnosing and monitoring CNO, (2) ordering a bone biopsy, and (3) making treatment decisions. Methods. A survey was distributed among members of the Childhood Arthritis and Rheumatology Research Alliance using a web-based questionnaire...
2017: International Journal of Rheumatology
https://www.readbyqxmd.com/read/28166919/a-lengthy-primary-intramedullary-tuberculoma-of-the-spinal-cord-extending-from-c4-to-d8-a-case-report
#10
V Chandramouleeswaran, Hazeena P Philo, D Balasubramaniam, Rajeswari Ramachandran
Spinal intramedullary tuberculoma is a rare cause of spinal cord compression. We report a case that had an intramedullary spinal cord tuberculomas where the diagnosis was made by MRI and biopsy. The clinical presentation was that of a cord compression in a 30-year-old male febrile patient. This case of intramedullary spinal tuberculoma with a longitudinally extending lesion of the cervicothoracic spine from C4 to D8 is presented for the rarity of its presentation.
January 2017: Indian Journal of Tuberculosis
https://www.readbyqxmd.com/read/28163523/primary-sacral-hydatid-cyst-mimicking-a-neurogenic-tumor-in-chronic-low-back-pain-case-report-and-review-of-the-literature
#11
Manuel Segura-Trepichio, Jose Manuel Montoza-Nuñez, David Candela-Zaplana, Josefa Herrero-Santacruz, Fernando Pla-Mingorance
Hydatid disease is caused by infection of Echinococcus granulosus. Bone hydatid cyst presentation without hepatic affectation is infrequent and occurs in 0,5-2% of cases. This rare condition makes clinicians not always aware of the disease, and as a result, misdiagnosis of spinal echinococcosis is common. We present a case of a 48-year-old female patient with primary sacral hydatidosis. Chronic low back pain radiating to the left buttock was the only symptom. The magnetic resonance imaging (MRI) suggested a neurogenic tumor versus giant cell tumor...
December 2016: Journal of Neurosciences in Rural Practice
https://www.readbyqxmd.com/read/28156208/image-guided-intrathecal-baclofen-pump-catheter-implantation-a-technical-note-and-case-series
#12
Shenandoah Robinson, Faith C Robertson, Hormuzdiyar H Dasenbrock, Cormac P O'Brien, Charles Berde, Horacio Padua
OBJECTIVE Medically refractory spasticity and dystonia are often alleviated with intrathecal baclofen (ITB) administration through an indwelling catheter inserted in the lumbar spine. In patients with cerebral palsy, however, there is a high incidence of concomitant neuromuscular scoliosis. ITB placement may be technically challenging in those who have severe spinal deformity or who have undergone prior instrumented thoracolumbar fusion. Although prior reports have described drilling through the lumbar fusion mass with a high-speed bur, as well as IT catheter implantation at the foramen magnum or cervical spine, these approaches have notable limitations...
February 3, 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/28154154/renal-cell-carcinoma-metastasis-involving-vertebral-hemangioma-dual-percutaneous-treatment-by-navigational-bipolar-radiofrequency-ablation-and-high-viscosity-cement-vertebroplasty
#13
Jean-Baptiste Zerlauth, Reto Meuli, Vincent Dunet
The case of a 70-year-old woman with progressive renal cell carcinoma (RCC) metastatic invasion of a L3 vertebral hemangioma treated by dual percutaneous radiofrequency ablation (RFA) and vertebroplasty is reported. The patient was surgically treated for RCC in 2001. Chemotherapy and immunotherapy were introduced in 2013 for ovarian, bladder and cerebral metastatic disease. An asymptomatic L3 benign hemangioma was noticed at this time. One-year CT and MRI follow-up studies demonstrated a nodular isolated soft tissue lesion involving the anterior edge of the hemangioma...
February 2, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28143487/helical-tomotherapy-of-spinal-chordomas-french-multicentric-retrospective-study-of-a-cohort-of-30-cases
#14
Maxime Bobin, Christina Zacharatou, Paul Sargos, Véronique Brouste, Albert Lisbona, Marc-André Mahé, Georges Noël, Amandine Halley, Loïc Feuvret, Louis Gras, Stéphanie Hoppe, Bénédicte Henriques de Figueiredo, Guy Kantor
PURPOSE: To evaluate the efficacy and toxicity of helical tomotherapy (HT) in the management of spine chordomas when proton therapy is unavailable or non-feasible. METHODS AND MATERIALS: Between 2007 and 2013, 30 patients with biopsy-proven chordomas were treated by HT in five French institutions. Information regarding local control (LC), overall survival (OS), progression-free survival (PFS) and metastasis-free survival (MFS) was collected. Clinical efficacy, toxicity and treatment quality were evaluated...
January 31, 2017: Radiation Oncology
https://www.readbyqxmd.com/read/28124423/clinical-management-of-brucella-suis-infection-in-dogs-and-implications-for-public-health
#15
D R James, G Golovsky, J M Thornton, L Goodchild, M Havlicek, P Martin, M B Krockenberger, Dje Marriott, V Ahuja, R Malik, S M Mor
BACKGROUND: Brucellosis caused by Brucella suis is a notifiable disease that has recently emerged in dogs in New South Wales (NSW). Given the potential for zoonotic transmission, euthanasia of affected dogs is recommended, but this action is not mandatory. We report the clinical management of three dogs that underwent treatment at their owners' request. CASE REPORTS: A 14-month-old spayed female crossbreed originally obtained from an urban animal shelter underwent extensive investigations in 2011-12 for lameness and back pain, culminating in decompressive laminectomy...
January 2017: Australian Veterinary Journal
https://www.readbyqxmd.com/read/28117331/early-spermatogenesis-changes-in-traumatic-complete-spinal-cord-injured-adult-patients
#16
A Sánchez-Ramos, E Vargas-Baquero, F J Martin-de Francisco, J A Godino-Durán, I Rodriguez-Carrión, M Ortega-Ortega, L Mordillo-Mateos, F Coperchini, M Rotondi, A Oliviero, M Mas
STUDY DESIGN: Prospective longitudinal study. OBJECTIVES: To assess the impact of spinal cord injury (SCI) on the spermatogenesis of patients studied in the early subacute stage and ensuing months. SETTING: National hospital for SCI patients. METHODS: A prospective follow-up study was conducted on 28 male patients with complete SCI who were evaluated in the early subacute phase (~1 month), and 3 and 6 months after the injury...
January 24, 2017: Spinal Cord
https://www.readbyqxmd.com/read/28105177/-18-f-fluoroethyl-l-tyrosine-positron-emission-tomography-guided-diagnosis-of-a-malignant-intramedullary-spinal-cord-tumor
#17
Sied Kebir, Okka Kimmich, Pitt Niehusmann, Florian C Gaertner, Markus Essler, Jennifer Landsberg, Thomas Klockgether, Matthias Simon, Ulrich Herrlinger, Martin Glas
Diagnosis in patients with a suspected malignant intramedullary lesion that requires biopsy for definitive diagnosis may be challenging, as spinal cord surgery carries the risk of irreversible neurological deficits. The current study presents the first case of (18)F-fluoroethyl-L-tyrosine ((18)F-FET) positron emission tomography (PET) imaging in a patient with a spinal cord tumor. The patient was unsuitable for magnetic resonance imaging due to his implanted cardiac defibrillator. (18)F-FET PET indicated a high-grade malignancy of the spinal cord, justifying tumor biopsy...
December 2016: Oncology Letters
https://www.readbyqxmd.com/read/28101825/neurosarcoidosis-clinical-presentations-and-changing-treatment-patterns-in-an-irish-caucasian-population
#18
K O'Connell, L Williams, J Jones, D J H McCabe, D Murphy, R Killeen, N Tubridy, S O'Riordan, C McGuigan
BACKGROUND: The clinical manifestations of neurosarcoidosis are highly variable and it should be considered as a potential differential diagnosis in any neurological presentation. AIM: This study was designed to describe the clinical, diagnostic, and treatment patterns and functional outcome in a Caucasian neurosarcoidosis population. DESIGN: A retrospective analysis was performed on prospectively recorded data in patients attending our neurology clinic between 2008 and 2014 with a diagnosis of definite or probable neurosarcoidosis according to Zajiek criteria...
January 18, 2017: Irish Journal of Medical Science
https://www.readbyqxmd.com/read/28098058/repair-of-an-inguinoscrotal-hernia-in-a-patient-with-becker-muscular-dystrophy
#19
F Tatulli, A Caraglia, A Delcuratolo, S Cassano, G S Chetta
INTRODUCTION: Inguinal hernia repairs are routinely performed as outpatient procedures in most patients, whereas a few require admission due to clinical or social peculiarities. Muscular dystrophies are inherited disorders characterized by progressive muscle wasting and weakness. In case of surgery there is no definite recommendation for either general or regional anesthesia. CASE REPORT: This contribution regards a 48 y. o. male patient diagnosed with Becker Muscular Dystrophy by muscle biopsy 10 years earlier...
September 2017: Il Giornale di Chirurgia
https://www.readbyqxmd.com/read/28097252/enterococcus-faecalis-causing-delayed-spondylodiscitis-in-a-case-with-retained-intraspinal-bullet
#20
Siddharth N Aiyer, Ajoy Prasad Shetty, Rishi Kanna, Srikanth Reddy, Shanmuganathan Rajasekaran
Delayed presentations have been reported following gunshot wounds (GSW) with retained intraspinal bullets due to migration of projectile or lead intoxication. We report on the rare occurrence of delayed pyogenic spondylodiscitis and neurological dysfunction following injury from low velocity GSW to the spine with a retained projectile. A 55-year-old male presented 4 months following GSW to the abdomen which resulted in colonic injury and L5 fracture. The patient was treated initially with ileo-transverse anastomosis, antibiotics, without retrieval of the bullet...
December 2016: Journal of Spine Surgery (Hong Kong)
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