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primary obesity surgery endolumenal

Nitin Kumar
Obesity and its comorbidities - including diabetes and obstructive sleep apnea - have taken a large and increasing toll on the United States and the rest of the world. The availability of commercial, clinical, and operative therapies for weight management have not been effective at a societal level. Endoscopic bariatric therapy is gaining acceptance as more effective than diet and lifestyle measures, and less invasive than bariatric surgery. Various endoscopic therapies are analogues of the restrictive or bypass components of bariatric surgery, utilizing gastric remodeling or intestinal anastomosis to achieve proven weight loss and metabolic benefits...
August 21, 2016: World Journal of Gastroenterology: WJG
J C Espinós, R Turró, G Moragas, A Bronstone, J N Buchwald, F Mearin, A Mata, H Uchima, J Turró, S Delgado-Aros
BACKGROUND: Primary Obesity Surgery Endolumenal (POSE) is a novel bariatric endoscopic procedure that has been shown to reduce weight safely through 12 months. The study investigated potential mechanisms of weight loss following POSE. METHODS: Patients with class I-II obesity received transmural plications in the gastric fundus and distal gastric body. Patients were evaluated at baseline and at 2- and 6-month follow-up with gastric-emptying (GE) scintigraphy, a validated test of intake capacity (kcal) and plasma glucose homeostasis hormones/gastrointestinal peptides...
May 2016: Obesity Surgery
Nitin Kumar
A new paradigm in the treatment of obesity and metabolic disease is developing. The global obesity epidemic continues to expand despite the availability of diet and lifestyle counseling, pharmacologic therapy, and weight loss surgery. Endoscopic procedures have the potential to bridge the gap between medical therapy and surgery. Current primary endoscopic bariatric therapies can be classified as restrictive, bypass, space-occupying, or aspiration therapy. Restrictive procedures include the USGI Primary Obesity Surgery Endolumenal procedure, endoscopic sleeve gastroplasty using Apollo OverStitch, TransOral GAstroplasty, gastric volume reduction using the ACE stapler, and insertion of the TERIS restrictive device...
July 25, 2015: World Journal of Gastrointestinal Endoscopy
Gontrand López-Nava, Inmaculada Bautista-Castaño, Amaya Jimenez, Teresa de Grado, Juan Pedro Fernandez-Corbelle
BACKGROUND: Obesity is at epidemic proportions and increasing. Bariatric surgical procedures have demonstrated better durable weight loss than diet and exercise; however, risk may limit adoption of these procedures. Endoscopic procedures may offer less risk, lower cost, and satisfactory results, but limited safety and outcome data is available. The present report describes the Primary Obesity Surgery Endolumenal (POSE(™)) procedure, perioperative care, and 1-year safety and weight loss outcomes for a single center...
July 2015: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
Kristen Buttelmann, John G Linn, Woody Denham, Melissa Ruiz, Amy Yetasook, Michael Ujiki
INTRODUCTION: Many patients do not maintain weight loss after gastric bypass. We compared outcomes for patients undergoing diet/exercise intervention with patients undergoing surgical intervention through restorative obesity surgery-endolumenal, band over bypass, and endoscopic gastro gastric fistula closure. METHODS: We hypothesized surgery would result in greater weight loss. A retrospective analysis was performed on a bariatric database. Patients who underwent gastric bypass and failed to lose weight were selected and evaluated after intervention...
February 2015: Surgical Laparoscopy, Endoscopy & Percutaneous Techniques
J C Espinós, R Turró, A Mata, M Cruz, M da Costa, V Villa, J N Buchwald, J Turró
BACKGROUND: We report our initial experience and 6-month outcomes in a single center using the per-oral Incisionless Operating Platform™ (IOP) (USGI Medical) to place transmural plications in the gastric fundus and distal body using specialized suture anchors (the Primary Obesity Surgery Endolumenal [POSE] procedure). METHODS: A prospective observational study was undertaken with institutional Ethics Board approval in a private hospital in Barcelona, Spain. Indicated patients were WHO obesity class I-II, or III, where patients refused a surgical approach...
September 2013: Obesity Surgery
Christopher C Thompson, Garth R Jacobsen, Gregory L Schroder, Santiago Horgan
BACKGROUND: Roux-en-Y gastric bypass (RYGB) is the most frequently performed bariatric procedure. However, weight regain after RYGB is common and often associated with pouch and stoma dilation. Historically, revision surgery has a greater risk of morbidity and mortality than the primary procedure. Endoscopic repair appears to be a safer option; however, current knowledge is limited regarding the longer term outcomes. Our objective was to prospectively collect the 12-month post-RYGB outcomes data after repair of dilated gastric tissue with an incisionless tissue approximation system in an open-label, single-group study at 9 U...
May 2012: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
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