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Saeid Hosseini, Yousef Rezaei, Niloufar Samiei, Zahra Emkanjoo, Mohammad Reza Dehghani, Majid Haghjoo, Luigi P Badano
No abstract text is available yet for this article.
November 1, 2016: International Journal of Cardiology
Mengkai Li, Zhimin Qiang, Pin Hou, James R Bolton, Jiuhui Qu, Peng Li, Chen Wang
Vacuum ultraviolet (VUV) and ultraviolet (UV)/chlorine processes are regarded as two of many advanced oxidation processes (AOPs). Because of the similar cost of VUV/UV and UV lamps, a combination of VUV and UV/chlorine (i.e., VUV/UV/chlorine) may enhance the removal of organic pollutants in water but without any additional power input. In this paper, a mini-fluidic VUV/UV photoreaction system (MVPS) was developed for bench-scale experiments, which could emit both VUV (185 nm) and UV (254 nm) or solely UV beams with a nearly identical UV photon fluence...
June 7, 2016: Environmental Science & Technology
Faisal F Syed, Michael J Ackerman, Christopher J McLeod, Suraj Kapa, Siva K Mulpuru, Chenni S Sriram, Bryan C Cannon, Samuel J Asirvatham, Peter A Noseworthy
BACKGROUND: Although the vast majority of mitral valve prolapse (MVP) is benign, a small subset of patients, predominantly women, with bileaflet prolapse, complex ventricular ectopy (VE), and abnormal T waves comprise the recently described bileaflet MVP syndrome. We compared findings on electrophysiological study in bileaflet MVP syndrome patients with and without cardiac arrest to identify factors that may predispose to malignant ventricular arrhythmia. METHODS AND RESULTS: Fourteen consecutive bileaflet MVP syndrome patients (n=13 women; median [limits], age at index ablation, 33...
May 2016: Circulation. Arrhythmia and Electrophysiology
Olivier Huttin, Sarah Pierre, Clément Venner, Damien Voilliot, Jean-Marc Sellal, Etienne Aliot, Nicolas Sadoul, Yves Juillière, Christine Selton-Suty
AIMS: Two-dimensional echocardiography often reveals abnormal left ventricle (LV) lateral wall kinetics in patients presenting with mitral valve prolapse (MVP). However, relations between MVP and LV deformation are not clearly established. The aim of this study was to assess and quantify mitral valve chordae, leaflets, and LV myocardial interactions using speckle tracking echocardiography (STE). METHODS AND RESULTS: Using STE-derived longitudinal strain curves, LV peak longitudinal strain (PLS, %), post-systolic index (PSI), and pre-stretch index (PST) were analysed in 100 patients with MVP and normal LV ejection fraction...
April 20, 2016: European Heart Journal Cardiovascular Imaging
Ji C Bihl, Christine M Rapp, Yanfang Chen, Jeffrey B Travers
The lipid mediator platelet-activating factor (PAF) and oxidized glycerophosphocholine PAF agonists produced by ultraviolet B (UVB) have been demonstrated to play a pivotal role in UVB-mediated processes, from acute inflammation to delayed systemic immunosuppression. Recent studies have provided evidence that microvesicle particles (MVPs) are released from cells in response to various signals including stressors. Importantly, these small membrane fragments can interact with various cell types by delivering bioactive molecules...
May 2016: Photochemistry and Photobiology
Ling Chong Wang, Hao Wu, Jing Ji, Feng Xue, Rui Liu
The polysaccharides from Mactra veneriformis (MVPS) were degraded by controlled mild acid hydrolysis to produce active oligosaccharides. MVPS can easily be hydrolyzed by H2SO4 or HCl. The hydrolyzing process was investigated in acid addition and reaction time by evaluating the producing content of reducing sugar. Hydrolysis with 1M HCl to MVPS can generate a time-depended behavior that is mild and controllable. HPLC analysis monitored the change of oligosaccharides composition in hydrolyzing. Total nine oligosaccharides are recognizable in the HPLC profile, and their content showed a regular transformation in hydrolysis...
February 10, 2016: Carbohydrate Polymers
Hugo Ja Adams, John Mh de Klerk, Rob Fijnheer, Ben Gf Heggelman, Stefan V Dubois, Rutger Aj Nievelstein, Thomas C Kwee
BACKGROUND: There is a lack of data on the effect of rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) therapy on brain glucose metabolism of diffuse large B-cell lymphoma (DLBCL) patients, as measured by 18F-fluoro-2-deoxy-D-glucose positron emission tomography (FDG-PET). Moreover, the prognostic value of brain glucose metabolism measurements is currently unknown. PURPOSE: To investigate the use of FDG-PET for measurement of brain glucose metabolism in R-CHOP-treated DLBCL patients, and to assess its prognostic value...
June 2016: Acta Radiologica
Xiaolian Gu, Elisabet Nylander, Philip J Coates, Robin Fahraeus, Karin Nylander
Epigenetic modifications by DNA methylation are associated with a wide range of diseases. Previous studies in psoriasis have concentrated on epigenetic changes in immune cells or in total skin biopsies that include stromal-associated changes. In order to improve our understanding of the role of DNA methylation in psoriasis, we sought to obtain a comprehensive DNA methylation signature specific for the epidermal component of psoriasis and to analyze methylation changes during therapy. Genome-wide DNA methylation profiling of epidermal cells from 12 patients undergoing narrow-band UVB phototherapy and 12 corresponding healthy controls revealed a distinct DNA methylation pattern in psoriasis compared with controls...
August 2015: Journal of Investigative Dermatology
Sarah Finer, Chris Mathews, Rob Lowe, Melissa Smart, Sara Hillman, Lin Foo, Ajay Sinha, David Williams, Vardhman K Rakyan, Graham A Hitman
Exposure of a developing foetus to maternal gestational diabetes (GDM) has been shown to programme future risk of diabetes and obesity. Epigenetic variation in foetal tissue may have a mechanistic role in metabolic disease programming through interaction of the pregnancy environment with gene function. We aimed to identify genome-wide DNA methylation variation in cord blood and placenta from offspring born to mothers with and without GDM. Pregnant women of South Asian origin were studied and foetal tissues sampled at term delivery...
June 1, 2015: Human Molecular Genetics
Long Chen, Zhi-Xiong Lin, Guo-Shi Lin, Chang-Fu Zhou, Yu-Peng Chen, Xing-Fu Wang, Zong-Qing Zheng
There are limited researches focusing on microvascular patterns (MVPs) in human glioblastoma and their prognostic impact. We evaluated MVPs of 78 glioblastomas by CD34/periodic acid-Schiff dual staining and by cluster analysis of the percentage of microvascular area for distinct microvascular formations. The distribution of 5 types of basic microvascular formations, that is, microvascular sprouting (MS), vascular cluster (VC), vascular garland (VG), glomeruloid vascular proliferation (GVP), and vasculogenic mimicry (VM), was variable...
January 2015: Human Pathology
Andreas Güldner, Thomas Kiss, Thomas Bluth, Christopher Uhlig, Anja Braune, Nadja Carvalho, Theresa Quast, Ines Rentzsch, Robert Huhle, Peter Spieth, Torsten Richter, Felipe Saddy, Patricia R M Rocco, Michael Kasper, Thea Koch, Paolo Pelosi, Marcelo Gama de Abreu
BACKGROUND: To investigate the role of ultraprotective mechanical ventilation (UP-MV) and extracorporeal carbon dioxide removal with and without spontaneous breathing (SB) to improve respiratory function and lung protection in experimental severe acute respiratory distress syndrome. METHODS: Severe acute respiratory distress syndrome was induced by saline lung lavage and mechanical ventilation (MV) with higher tidal volume (VT) in 28 anesthetized pigs (32.8 to 52...
March 2015: Anesthesiology
Efstratios K Theofilogiannakos, Konstantinos Dean Boudoulas, Brian E Gawronski, Taimour Y Langaee, Petros S Dardas, Vlasis Ninios, Timotheos G Kelpis, Julie A Johnson, Antonios A Pitsis, Harisios Boudoulas
BACKGROUND: Certain patients with floppy mitral valve (FMV)/mitral valve prolapse (MVP) may have symptoms that cannot be explained on the severity of mitral valvular regurgitation (MVR) alone; hypersensitivity to adrenergic stimulation has been suggested in this group defined as the FMV/MVP syndrome. METHODS: Ninety-eight patients (75 men, 23 women) with mitral valve surgery for FMV/MVP were studied. Of those 41 (42%) had symptoms consistent with FMV/MVP syndrome [29 men (39%), 12 women (52%)]; median age of symptom onset was 30 years (range 10-63 years) and median duration of symptoms prior to valve surgery was 16 years (range 3-50 years)...
May 2015: Journal of Cardiology
Marc N Coutanche, Sharon L Thompson-Schill
It is now appreciated that condition-relevant information can be present within distributed patterns of functional magnetic resonance imaging (fMRI) brain activity, even for conditions with similar levels of univariate activation. Multi-voxel pattern (MVP) analysis has been used to decode this information with great success. FMRI investigators also often seek to understand how brain regions interact in interconnected networks, and use functional connectivity (FC) to identify regions that have correlated responses over time...
2014: Journal of Visualized Experiments: JoVE
Hamid Amoozgar, Hashem Rafizadeh, Gholamhossein Ajami, Mohammad Borzoee
BACKGROUND: A paucity of data exists regarding the prevalence and relationship of hypomagnesaemia with clinical symptoms of mitral valve prolapse (MVP) in pediatric patients. OBJECTIVE: In this study we evaluated the prevalence of magnesium (Mg) deficiency in pediatric patients with MVP syndrome and attempted to clarify the effect of Mg therapy on alleviating their symptoms. METHODS: The present study was conducted from April 2010 to January 2012, and included 230 patients (90 males and 140 females) with symptoms of mitral valve prolapse and mean age of 11...
September 2012: International Cardiovascular Research Journal
Mohammad Mehdi Peighambari, Azin Alizadehasl, Ziae Totonchi
INTRODUCTION: Mitral valve prolapse syndrome (MVP) is the most common valvular abnormalityin the young and is correlated with increased frequency of cardiac dysrhythmias and sudden death.The aim of this study was to compare frequency of "early repolarization" in electrocardiogram(ECG) between MVP patients and healthy adults. METHODS: In this cross-sectional study, we compared ECG presentations of early repolarizationincluding notch in descending arm of QRS and J-point and/or ST segment changes in 100 patientswith MVP with 100 healthy individuals...
2014: Journal of Cardiovascular and Thoracic Research
Yang-Yang Yue, Gui-Sen Zhao, Qian Zhang, Di Lu, Xian-Dun Zhai, Yao-Nan Mo
OBJECTIVE: To develop the single-tube one-step methylation variable position (MVP) analysis technology-single-tube post-digestion PCR-melting curve analysis (PDP-MCA). METHODS: Based on differentially methylated region (DMR) reported previously as the model, a set of primers with different melting temperatures of products in the two sides of MVP were designed. By using the FastDigest methylation-sensitive restriction enzyme (MSRE), DNA digestion, multiplex amplification, MCA detection and MCA profiles were performed in a single reaction tube...
December 2013: Fa Yi Xue za Zhi
Brian T Wilson, Sacha A Jensen, Ciaron P McAnulty, Paul Brennan, Penny A Handford
Mutations in Fibrillin 1 (FBN1) are associated with Marfan syndrome and in some instances with the MASS phenotype (myopia, mitral valve prolapse, borderline non-progressive aortic root dilatation, skeletal features, and striae). Potential confusion over diagnosis and management in patients with borderline features has been addressed through the revised Ghent nosology, which emphasizes the importance of aortic root dilatation and ectopia lentis as features of Marfan syndrome. The overlapping and more common mitral valve prolapse syndrome is precluded by ectopia lentis or aortic dilatation...
August 2013: American Journal of Medical Genetics. Part A
Nicolas S Valentin, Kristin N Hageman, Chenkai Dai, Charles C Della Santina, Gene Y Fridman
No adequate treatment exists for individuals who remain disabled by bilateral loss of vestibular (inner ear inertial) sensation despite rehabilitation. We have restored vestibular reflexes using lab-built multichannel vestibular prostheses (MVPs) in animals, but translation to clinical practice may be best accomplished by modification of a commercially available cochlear implant (CI). In this interim report, we describe preliminary efforts toward that goal. We developed software and circuitry to sense head rotation and drive a CI's implanted stimulator (IS) to deliver up to 1 K pulses/s via nine electrodes implanted near vestibular nerve branches...
September 2013: IEEE Transactions on Neural Systems and Rehabilitation Engineering
Karan Bhagwawan Khairnar, Prashant Amanrao Bhusari
INTRODUCTION: An anatomical study was undertaken to note the shape of the foramen ovale(FO), foramen spinosum (FS) & presence or absence of canalis innominatus. FO is present in the posterior part of the greater wing of sphenoid. FS is located posterolareral to foramen ovale. Aims & Objective: We attempted this study to find out the variations in shape, bony growth & divisions of FO & FS in available dry human skulls. MATERIAL & METHODS: We studied 100 human skulls available in the Department of Anatomy MVPS Medical College, Nashik...
March 2013: Journal of Clinical and Diagnostic Research: JCDR
Chenni S Sriram, Faisal F Syed, M Eric Ferguson, Jonathan N Johnson, Maurice Enriquez-Sarano, Frank Cetta, Bryan C Cannon, Samuel J Asirvatham, Michael J Ackerman
OBJECTIVES: The aim of this study was to investigate the prevalence of mitral valve prolapse (MVP) and its association with ventricular arrhythmias in a cohort with "unexplained" out-of-hospital cardiac arrest. BACKGROUND: Ventricular arrhythmias are an important cause of sudden unexpected death in the young. The role of MVP in sudden unexpected death remains controversial. METHODS: Of 1,200 patients evaluated between July 2000 and December 2009 in the Mayo Clinic's Long QT Syndrome/Genetic Heart Rhythm Clinic, all 24 (16 women, median age 33...
July 16, 2013: Journal of the American College of Cardiology
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