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https://www.readbyqxmd.com/read/27909226/unique-cytokine-and-chemokine-responses-to-exertional-heat-stroke-in-mice
#1
Michelle A King, Lisa R Leon, Deborah A Morse, Thomas L Clanton
In heat stroke, cytokines are believed to play important roles in multi-organ dysfunction and recovery of damaged tissue. The time course of the cytokine response is well defined in passive heat stroke (PHS), but little is known about exertional heat stroke (EHS). In this study we used a recently developed mouse EHS model to measure the responses of circulating cytokines/chemokines and cytokine gene expression in muscle. A very rapid increase in circulating IL-6 was observed at max core temperature (Tc,max) that peaked at 0...
December 1, 2016: Journal of Applied Physiology
https://www.readbyqxmd.com/read/27904960/active-and-passive-involvement-of-claudins-in-the-pathophysiology-of-intestinal-inflammatory-diseases
#2
REVIEW
Christian Barmeyer, Michael Fromm, Jörg-Dieter Schulzke
Intestinal inflammatory diseases, four of which are discussed here, are associated with alterations of claudins. In ulcerative colitis, diarrhea and antigen entry into the mucosa occurs. Claudin-2 is upregulated but data on other claudins are still limited or vary (e.g., claudin-1 and -4). Apart from that, tight junction changes contribute to diarrhea via a leak flux mechanism, while protection against antigen entry disappears behind epithelial gross lesions (erosions) and apoptotic foci. Crohn's disease is additionally characterized by a claudin-5 and claudin-8 reduction which plays an active role in antigen uptake already before gross lesions appear...
November 30, 2016: Pflügers Archiv: European Journal of Physiology
https://www.readbyqxmd.com/read/27900211/in-vivo-expression-of-reprogramming-factors-increases-hippocampal-neurogenesis-and-synaptic-plasticity-in-chronic-hypoxic-ischemic-brain-injury
#3
Soohyun Wi, Ji Hea Yu, MinGi Kim, Sung-Rae Cho
Neurogenesis and synaptic plasticity can be stimulated in vivo in the brain. In this study, we hypothesized that in vivo expression of reprogramming factors such as Klf4, Sox2, Oct4, and c-Myc would facilitate endogenous neurogenesis and functional recovery. CD-1® mice were induced at 1 week of age by unilaterally carotid artery ligation and exposure to hypoxia. At 6 weeks of age, mice were injected GFP only or both four reprogramming factors and GFP into lateral ventricle. Passive avoidance task and open field test were performed to evaluate neurobehavioral function...
2016: Neural Plasticity
https://www.readbyqxmd.com/read/27882029/effects-of-comprehensive-rehabilitation-training-in-combination-with-multi-mode-analgesia-on-body-function-recovery-after-tumor-type-knee-replacement
#4
Junjuan Zhang, Yahan Wang, Guangyu Yang, Jing Liu, Junjie Wang
OBJECTIVE: To discuss the significance of comprehensive rehabilitation training combined with multimodal analgesia (MMA) for the early knee function recovery of patients with knee bone tumor who underwent prosthesis replacement operation. METHODS: Sixty patients with knee bone tumor who underwent prosthesis replacement operation were selected and randomly divided into two groups according to rehabilitation training and postoperative analgesic methods, namely, observation group and control group, 30 cases in each group...
September 2016: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/27876449/reduction-in-spasticity-in-stroke-patient-with-paraffin-therapy
#5
Jing Wang, Peng Yu, Ming Zeng, Xudong Gu, Yan Liu, Mingyue Xiao
PURPOSE: The aim of the study was to confirm whether paraffin therapy offer clinical value in the treatment of spasticity due to stroke. METHODS: Fifty-two patients with spasticity in the upper limb were included. The patients were randomized into the experimental group with paraffin therapy (n = 27) and the control group with placebo therapy (n = 25). The outcome measures besides temperature examination were undertaken at time points of 0 (T0), 2 (T1) and 4 weeks (T2) following therapy treatment...
November 23, 2016: Neurological Research
https://www.readbyqxmd.com/read/27875927/what-is-being-trained-how-divergent-forms-of-plasticity-compete-to-shape-locomotor-recovery-after-spinal-cord-injury
#6
J Russell Huie, Kazuhito Morioka, Jenny Haefeli, Adam R Ferguson
Spinal cord injury (SCI) is a devastating syndrome that produces dysfunction in motor and sensory systems, manifesting as chronic paralysis, sensory changes, and pain disorders. The multifaceted and heterogeneous nature of SCI has made effective rehabilitative strategies challenging. Work over the last 40 years has aimed to overcome these obstacles by harnessing the intrinsic plasticity of the spinal cord to improve functional locomotor recovery. Intensive training after SCI facilitates lower extremity function and has shown promise as a tool for retraining the spinal cord by engaging innate locomotor circuitry in the lumbar cord...
November 22, 2016: Journal of Neurotrauma
https://www.readbyqxmd.com/read/27867360/inflammatory-cytokines-and-bdnf-response-to-high-intensity-intermittent-exercise-effect-the-exercise-volume
#7
Carolina Cabral-Santos, Carlos I M Castrillón, Rodolfo A T Miranda, Paula A Monteiro, Daniela S Inoue, Eduardo Z Campos, Peter Hofmann, Fábio S Lira
The purpose of this study was to compare the effects of two similar high-intensity intermittent exercises (HIIE) but different volume 1.25 km (HIIE1.25) and 2.5 km (HIIE2.5) on inflammatory and BDNF responses. Ten physically active male subjects (age 25.22 ± 1.74 years, body mass 78.98 ± 7.31 kg, height 1.78 ± 0.06 m, VO2peak 59.94 ± 9.38 ml·kg·min(-1)) performed an incremental treadmill exercise test and randomly completed two sessions of HIIE on a treadmill (1:1 min at vVO2max with passive recovery)...
2016: Frontiers in Physiology
https://www.readbyqxmd.com/read/27867260/tracking-sentence-comprehension-test-retest-reliability-in-people-with-aphasia-and-unimpaired-adults
#8
Jennifer E Mack, Andrew Zu-Sern Wei, Stephanie Gutierrez, Cynthia K Thompson
PURPOSE: Visual-world eyetracking is increasingly used to investigate online language processing in normal and language impaired listeners. Tracking changes in eye movements over time also may be useful for indexing language recovery in those with language impairments. Therefore, it is critical to determine the test-retest reliability of results obtained using this method. METHODS: Unimpaired young adults and people with aphasia took part in two eyetracking sessions spaced about one week apart...
November 2016: Journal of Neurolinguistics
https://www.readbyqxmd.com/read/27852904/the-relationship-between-shoulder-stiffness-and-rotator-cuff-healing-a-study-of-1-533-consecutive-arthroscopic-rotator-cuff-repairs
#9
William J McNamara, Patrick H Lam, George A C Murrell
BACKGROUND: Retear and stiffness are not uncommon outcomes of rotator cuff repair. The purpose of this study was to evaluate the relationship between rotator cuff repair healing and shoulder stiffness. METHODS: A total of 1,533 consecutive shoulders had an arthroscopic rotator cuff repair by a single surgeon. Patients assessed their shoulder stiffness using a Likert scale preoperatively and at 1, 6, 12, and 24 weeks (6 months) postoperatively, and examiners evaluated passive range of motion preoperatively and at 6, 12, and 24 weeks postoperatively...
November 16, 2016: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/27849465/outcomes-associated-with-the-intrepid-dynamic-exoskeletal-orthosis-ideo-a-systematic-review-of-the-literature
#10
M Jason Highsmith, Leif M Nelson, Neil T Carbone, Tyler D Klenow, Jason T Kahle, Owen T Hill, Jason T Maikos, Mike S Kartel, Billie J Randolph
High-energy lower extremity trauma is a consequence of modern war and it is unclear if limb amputation or limb salvage enables greater recovery. To improve function in the injured extremity, a passive dynamic ankle-foot orthosis, the Intrepid Dynamic Exoskeletal Orthosis (IDEO), was introduced with specialized return to run (RTR) therapy program. Recent research suggests, these interventions may improve function and return to duty rates. This systematic literature review sought to rate available evidence and formulate empirical evidence statements (EESs), regarding outcomes associated with IDEO utilization...
November 2016: Military Medicine
https://www.readbyqxmd.com/read/27837361/analytical-evaluation-of-the-protection-offered-by-sealed-tractor-cabins-during-crop-pulverization-with-fenitrothion
#11
Michelle Barcellos, Milena Michele Faletti, Luiz Augusto Dos Santos Madureira, Fernando Cesar Bauer
The practice of large-scale agriculture requires the use of pesticides in order to maximize production. This activity has gained increasing attention in recent years, especially from rural workers, due to the risks associated with long-term exposure to pesticides. To minimize these risks, personal protection equipment (e.g., covers, gloves, and goggles) and collective protection equipment (e.g., agricultural tractors with sealed cabins) have been developed. In general, these approaches are intended to reduce the contact of farmers and agricultural machinery operators with the more toxic and stable compounds, an example of which is fenitrothion...
December 0: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/27815003/an-assessment-of-the-effectiveness-of-a-long-term-ecosystem-restoration-project-in-a-fynbos-shrubland-catchment-in-south-africa
#12
Jennifer M Fill, Greg G Forsyth, Suzaan Kritzinger-Klopper, David C Le Maitre, Brian W van Wilgen
The long-term effectiveness of ecological restoration projects is seldom reported in the scientific literature. This paper reports on the outcomes of ecosystem restoration following the clearing of alien Pinus plantations and associated alien plant invasions over 13 years from an 8000 ha mountain catchment in the Western Cape Province, South Africa. We examined the goals, methods and costs of management, and the ecological outcomes in terms of reduced alien plant cover and native vegetation recovery. While the goals were not explicitly formulated at the outset, they were implicitly focussed on the conservation of water resources, the restoration of biodiversity, and the provision of employment...
January 1, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/27814869/neurodynamic-treatment-for-patients-with-nerve-related-leg-pain-protocol-for-a-randomized-controlled-trial
#13
Giovanni E Ferreira, Fábio F Stieven, Francisco X Araújo, Matheus Wiebusch, Carolina G Rosa, Rodrigo Della Méa Plentz, Marcelo F Silva
OBJECTIVES: To investigate if neurodynamic treatment is more effective than advice to remain active in patients with nerve-related leg pain. DESIGN: Parallel-group randomized controlled trial blinded to the outcome assessor conducted in Porto Alegre, Brazil. PARTICIPANTS: Sixty patients recruited from the community and private practices. INTERVENTION: Patients will be randomly assigned to receive four sessions of neurodynamic treatment over two weeks comprising passive lumbar foramen opening and neurodynamic sliders plus home exercises or advice to remain active...
October 2016: Journal of Bodywork and Movement Therapies
https://www.readbyqxmd.com/read/27807528/postprandial-lipoprotein-profile-in-two-modes-of-high-intensity-intermittent-exercise
#14
Valéria Leme Gonçalves Panissa, Ursula Ferreira Julio, Tiego Aparecido Diniz, Barbara de Moura Mello Antunes, Fabio Santos Lira, Monica Yuri Takito, Emerson Franchini
The aim of present study was to compare blood lipid postprandial profile response in two modes of high-intensity intermittent exercise. Twelve individuals (6 men and 6 women) were submitted to a maximal incremental test (to determine maximal aerobic power [MAP] and V. O2peak [peak oxygen uptake]), high-intensity intermittent all-out exercise (60×8-sec bouts interspersed by 12-sec passive recovery) and fixed high-intensity intermittent exercise (100% maximal aerobic speed, consisted of 1-min repetitions at MAP [70 rpm] separated by 1-min of passive recovery)...
October 2016: Journal of Exercise Rehabilitation
https://www.readbyqxmd.com/read/27786541/postexercise-cold-water-immersion-improves-intermittent-high-intensity-exercise-performance-in-normothermia
#15
Avina McCarthy, James Mulligan, Mikel Egaña
A brief cold water immersion between 2 continuous high-intensity exercise bouts improves the performance of the latter compared with passive recovery in the heat. We investigated if this effect is apparent in normothermic conditions (∼19 °C), employing an intermittent high-intensity exercise designed to reflect the work performed at the high-intensity domain in team sports. Fifteen young active men completed 2 exhaustive cycling protocols (Ex1 and Ex2: 12 min at 85% ventilatory threshold (VT) and then an intermittent exercise alternating 30-s at 40% peak power (Ppeak) and 30 s at 90% Ppeak to exhaustion) separated by 15 min of (i) passive rest, (ii) 5-min cold-water immersion at 8 °C, and (iii) 10-min cold-water immersion at 8 °C...
July 25, 2016: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/27777795/limited-effects-of-endurance-or-interval-training-on-visceral-adipose-tissue-and-systemic-inflammation-in-sedentary-middle-aged-men
#16
Joshua H F Cooper, Blake E G Collins, David R Adams, Robert A Robergs, Cheyne E Donges
Purpose. Limited data exists for the effects of sprint-interval training (SIT) and endurance training (ET) on total body composition, abdominal visceral adipose tissue, and plasma inflammation. Moreover, whether "active" or "passive" recovery in SIT provides a differential effect on these measures remains uncertain. Methods. Sedentary middle-aged men (n = 62; 49.5 ± 5.8 y; 29.7 ± 3.7 kg·m(2)) underwent abdominal computed tomography, dual-energy X-ray absorptiometry, venepuncture, and exercise testing before and after the interventions, which included the following: 12 wks 3 d·wk(-1) ET (n = 15; 50-60 min cycling; 80% HRmax), SIT (4-10 × 30 s sprint efforts) with passive (P-SIT; n = 15) or active recovery (A-SIT; n = 15); or nonexercise control condition (CON; n = 14)...
2016: Journal of Obesity
https://www.readbyqxmd.com/read/27771950/sediment-monitored-natural-recovery-evidenced-by-compound-specific-isotope-analysis-and-high-resolution-pore-water-sampling
#17
Elodie Passeport, Richard Landis, Georges Lacrampe-Couloume, Edward J Lutz, Elizabeth Erin Mack, Kathryn West, Scott Morgan, Barbara Sherwood Lollar
Monitoring natural recovery of contaminated sediments requires the use of techniques that can provide definitive evidence of in situ contaminant degradation. In this study, a passive diffusion sampler, called "peeper", was combined with Compound Specific Isotope Analysis to determine benzene and monochlorobenzene (MCB) stable carbon isotope values at a fine vertical resolution (3 cm) across the sediment water interface at a contaminated site. Results indicated significant decrease in concentrations of MCB from the bottom to the top layers of the sediment over 25 cm, and a 3...
October 23, 2016: Environmental Science & Technology
https://www.readbyqxmd.com/read/27765844/intermittent-hypobaric-hypoxia-combined-with-aerobic-exercise-improves-muscle-morphofunctional-recovery-after-eccentric-exercise-to-exhaustion-in-trained-rats
#18
David Rizo-Roca, Juan Gabriel Ríos-Kristjánsson, Cristian Núñez-Espinosa, Estela Santos-Alves, Ines O Goncalves, Jose Magalhaes, Antonio A Ascensao, Teresa Pagès, Ginés Viscor, Joan Ramon Torrella
Unaccustomed eccentric exercise leads to muscle morphological and functional alterations, including microvasculature damage, the repair of which is modulated by hypoxia. Here we present the effects of intermittent hypobaric hypoxia and exercise on recovery from eccentric-induced muscle damage (EEIMD). Soleus muscles from trained rats were excised pre- (CTRL) and 1, 3, 7 and 14 days after a double session of EEIMD protocol. A recovery treatment consisting of one of the following protocols was applied one day after the EEIMD: passive normobaric recovery (PNR), a 4-hour daily exposure to passive hypobaric hypoxia at 4000m (PHR) or hypobaric hypoxia exposure followed by aerobic exercise (AHR)...
October 20, 2016: Journal of Applied Physiology
https://www.readbyqxmd.com/read/27763711/near-ultraviolet-fluorescent-on-off-on-switching-sensors-based-on-nitrogen-enrichment-dual-color-single-functional-polymer-carbon-nanosheets
#19
Zhong-Xia Wang, Fen-Ying Kong, Wei Wang
Graphene quantum dots-like structures of highly enriched nitrogen-based dual-color single-functional polymer carbon nanosheets (GLNPCNs) with an average diameter as large as 170 nm (~5 layers) are prepared by a facile hydrothermal method. Intermolecular C5H5N5···C5H5N5 or/and C2H5OH chemical polymerization interactions in the liquid state of the peripheral crown ether-like "hole" decorated compound GLNPCNs lead to a fascinating 2D supramolecular polymer architecture, which exhibits near-ultraviolet (NUV) fluorescence, narrow full width at half maximum, and excellent practical application capability...
October 20, 2016: Chemistry: a European Journal
https://www.readbyqxmd.com/read/27757745/recovery-and-reuse-of-sludge-from-active-and-passive-treatment-of-mine-drainage-impacted-waters-a-review
#20
Tsiverihasina V Rakotonimaro, Carmen Mihaela Neculita, Bruno Bussière, Mostafa Benzaazoua, Gérald J Zagury
The treatment of mine drainage-impacted waters generates considerable amounts of sludge, which raises several concerns, such as storage and disposal, stability, and potential social and environmental impacts. To alleviate the storage and management costs, as well as to give the mine sludge a second life, recovery and reuse have recently become interesting options. In this review, different recovery and reuse options of sludge originating from active and passive treatment of mine drainage are identified and thoroughly discussed, based on available laboratory and field studies...
October 18, 2016: Environmental Science and Pollution Research International
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