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https://www.readbyqxmd.com/read/29332237/acute-acetaminophen-ingestion-improves-performance-and-muscle-activation-during-maximal-intermittent-knee-extensor-exercise
#1
Paul T Morgan, Joanna L Bowtell, Anni Vanhatalo, Andrew M Jones, Stephen J Bailey
AIM: Acetaminophen is a commonly used medicine for pain relief and emerging evidence suggests that it may improve endurance exercise performance. This study investigated some of the physiological mechanisms by which acute acetaminophen ingestion might blunt muscle fatigue development. METHODS: Thirteen active males completed 60 × 3 s maximum voluntary contractions (MVC) of the knee extensors with each contraction separated by a 2 s passive recovery period...
January 13, 2018: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/29324474/active-and-inactive-leg-hemodynamics-during-sequential-single-leg-interval-cycling
#2
Nicole Gordon, Chris R Abbiss, Mohammed Ihsan, Andrew J Maiorana, Jeremiah J Peiffer
INTRODUCTION: Leg order during sequential single-leg cycling (i.e. exercising both legs independently within a single session) may affect local muscular responses potentially influencing adaptations. This study examined the cardiovascular and skeletal muscle hemodynamic responses during double-leg and sequential single-leg cycling. METHODS: Ten young healthy adults (28 ± 6 y) completed six 1-min double-leg intervals interspersed with one minute of passive recovery and, on a separate occasion, 12 (six with one leg followed by six with the other leg) 1-min single-leg intervals interspersed with one minute of passive recovery...
January 11, 2018: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/29313356/sub-cellular-nanorheology-reveals-lysosomal-viscosity-as-a-reporter-for-lysosomal-storage-diseases
#3
John Devany, Kasturi Chakraborty, Yamuna Krishnan
We describe a new method to measure viscosity within sub-cellular organelles of a living cell using nanorheology. We demonstrate proof of concept by measuring viscosity in lysosomes in multiple cell types and disease models. The lysosome is an organelle, which is responsible for the breakdown of complex biomolecules. When different lysosomal proteins are defective, they are unable to breakdown specific biological substrates, that get stored within the lysosome, causing about 70 fatal diseases called lysosomal storage disorders (LSDs)...
January 9, 2018: Nano Letters
https://www.readbyqxmd.com/read/29304124/the-effect-of-dna-degradation-bias-in-passive-sampling-devices-on-metabarcoding-studies-of-arthropod-communities-and-their-associated-microbiota
#4
Henrik Krehenwinkel, Marisa Fong, Susan Kennedy, Edward Greg Huang, Suzuki Noriyuki, Luis Cayetano, Rosemary Gillespie
PCR amplification bias is a well-known problem in metagenomic analysis of arthropod communities. In contrast, variation of DNA degradation rates is a largely neglected source of bias. Differential degradation of DNA molecules could cause underrepresentation of taxa in a community sequencing sample. Arthropods are often collected by passive sampling devices, like malaise traps. Specimens in such a trap are exposed to varying periods of suboptimal storage and possibly different rates of DNA degradation. Degradation bias could thus be a significant issue, skewing diversity estimates...
2018: PloS One
https://www.readbyqxmd.com/read/29280263/superior-self-powered-room-temperature-chemical-sensing-with-light-activated-inorganic-halides-perovskites
#5
Hongjun Chen, Meng Zhang, Renheng Bo, Chog Barugkin, Jianghui Zheng, Qingshan Ma, Shujuan Huang, Anita W Y Ho-Baillie, Kylie R Catchpole, Antonio Tricoli
Hybrid halide perovskite is one of the promising light absorber and is intensively investigated for many optoelectronic applications. Here, the first prototype of a self-powered inorganic halides perovskite for chemical gas sensing at room temperature under visible-light irradiation is presented. These devices consist of porous network of CsPbBr3 (CPB) and can generate an open-circuit voltage of 0.87 V under visible-light irradiation, which can be used to detect various concentrations of O2 and parts per million concentrations of medically relevant volatile organic compounds such as acetone and ethanol with very quick response and recovery time...
December 27, 2017: Small
https://www.readbyqxmd.com/read/29280235/first-signs-of-macroinvertebrate-recovery-following-enhanced-restoration-of-boreal-streams-used-for-timber-floating
#6
Francesca Pilotto, Christer Nilsson, Lina E Polvi, Brendan G McKie
Although ecological restoration generally succeeds in increasing physical heterogeneity, many projects fail to enhance biota. Researchers have suggested several possible explanations, including insufficient restoration intensity, or time-lags in ecological responses that prevent detection of significant changes in short-term monitoring programs. This study aims to evaluate whether benthic macroinvertebrate communities responded to an expanded set of stream restoration measures within a study period of one to five years after completion of the restoration project...
December 26, 2017: Ecological Applications: a Publication of the Ecological Society of America
https://www.readbyqxmd.com/read/29261429/baseline-intraocular-pressure-is-associated-with-subjective-sensitivity-to-physical-exertion-in-young-males
#7
Jesús Vera, Raimundo Jiménez, José Antonio García, José Cesar Perales, David Cárdenas
PURPOSE: The purposes of this study were to (a) investigate the effect of physical effort (cycling for 60 min at 60 ± 5% of individually computed reserve heart-rate capacity), combined with 2 different levels of cognitive demand (2-back, oddball), on intraocular pressure (IOP) and subjective judgments of perceived exertion (ratings of perceived exertion [RPE]), affect (Affective Valence subscale of the Self-Assessment Manikin [SAM]), and mental workload (National Aeronautics and Space Administration Task Load Index [NASA-TLX]); and (b) ascertain whether baseline IOP, measured before exercise, is associated with individual differences in subjective assessments of effort and affective response during exercise...
December 20, 2017: Research Quarterly for Exercise and Sport
https://www.readbyqxmd.com/read/29250338/early-recovery-after-hip-arthroscopy-for-femoroacetabular-impingement-syndrome-a-prospective-observational-study
#8
D J Cunningham, B D Lewis, C A Hutyra, R C Mather, S A Olson
The early post-operative course after hip arthroscopy for femoroacetabular impingement syndrome has not been thoroughly characterized or correlated to factors that may influence recovery. The aim of this study was to report on early pain, function and attitudes towards rehabilitation and to determine predictors of early recovery after hip arthroscopy. Sixty-two patients reported pre-operative pain, iHOT-12 (hip functional score), psychological status and other baseline characteristics. Pain, iHOT-12, hip flexion and several other outcomes were measured through 6 weeks post-operative...
December 2017: Journal of Hip Preservation Surgery
https://www.readbyqxmd.com/read/29249177/active-recovery-intervals-restore-initial-performance-after-repeated-sprints-in-swimming
#9
Ioannis D Kostoulas, Argyris G Toubekis, Thrasivoulos Paxinos, Konstantinos Volaklis, Savvas P Tokmakidis
The purpose of this study was to examine the effects of active recovery (AR) and passive recovery (PR) using short (2-min) and long (4-min) intervals on swimming performance. Twelve male competitive swimmers completed a progressively increasing speed test of 7 × 200-m swimming repetitions to locate the speed before the onset of curvilinear increase in blood lactate concentration (LT1). Subsequently, performance time of 6 × 50-m sprints was recorded during four different conditions: (i) 2-min PR (PR-2), (ii) 4-min PR (PR-4), (iii) 2-min AR (AR-2) and (iv) 4-min AR (AR-4) intervals...
December 17, 2017: European Journal of Sport Science
https://www.readbyqxmd.com/read/29244861/reliability-of-the-parameters-of-the-power-duration-relationship-using-maximal-effort-time-trials-under-laboratory-conditions
#10
Christoph Triska, Bettina Karsten, Bernd Heidegger, Bernhard Koller-Zeisler, Bernhard Prinz, Alfred Nimmerichter, Harald Tschan
The purpose of this study was to assess the reliability of critical power (CP) and the total amount of work accomplished above CP (W´) across repeated tests using ecologically valid maximal effort time-trials (TT) under laboratory conditions. After an initial incremental exercise test, ten well-trained male triathletes (age: 28.5 ± 4.7 years; body mass: 73.3 ± 7.9 kg; height: 1.80 ± 0.07 m; maximal aerobic power [MAP]: 329 ± 41 W) performed three testing sessions (Familiarization, Test I and Test II) each comprising three TT (12, 7, and 3 min with a passive recovery of 60 min between trials)...
2017: PloS One
https://www.readbyqxmd.com/read/29239983/effects-of-2-dehydration-on-lactate-concentration-during-constant-load-cycling
#11
J M Green, Miller Bl, J D Simpson, Dubroc Dr, Keyes Aa, Neal Kk, Gann Jj, Andre Tl
The lactate [La] threshold can predict endurance performance potential. Dehydration may alter [La] threshold. This study examined effects of dehydration on [La] response during constant load cycling. Recreationally fit (VO2 peak = 48.7 ± 5.2 ml•kg•min) male participants (n=9) completed 2 x 40 min constant-load cycling trials; euhydrated (HYD) and following previous evening passive (water bath) dehydration (2% body weight, DEH) (HYD and DEH counterbalanced). [La], heart rate (HR), 10 point Omni Ratings of Perceived Exertion (RPE) and rectal temperature (Trec) were measured following warm-up and at 10, 20, 30, and 40 min...
December 11, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29238980/influence-of-paeoniflorin-and-menthol-on-puerarin-transport-across-mdck-and-mdck-mdr1-cells-as-blood-brain-barrier-in%C3%A2-vitro-model
#12
Bing Yang, Shouying Du, Yang Lu, Shan Jia, Mengdi Zhao, Jie Bai, Pengyue Li, Huichao Wu
OBJECTIVE: Our objective of this research was (1) to investigate the transport characteristics of puerarin through MDCK-MDR1 and MDCK cells and (2) to evaluate the effects of paeoniflorin and menthol on puerarin transport so as to (3) explore the enhancement mechanism. METHODS: The cytotoxicity of drugs on MDCK and MDCK-MDR1 was evaluated by the MTT assay, and the transport studies were performed in both directions. The membrane fluidity was evaluated by fluorescence recovery after photobleaching, and the membrane potential was estimated by the accumulation of DiBAC4(3) in the cells...
December 13, 2017: Journal of Pharmacy and Pharmacology
https://www.readbyqxmd.com/read/29227869/reliability-of-oscillometric-central-blood-pressure-responses-to-lower-limb-resistance-exercise
#13
Simon Fryer, Keeron Stone, Tabitha Dickson, James Faulkner, Danielle Lambrick, Pablo Corres, Lauren Jerred, Lee Stoner
BACKGROUND AND AIMS: Although it is well known that resistance training (RT) is beneficial for patients suffering from a variety of cardiovascular diseases, it remains underutilized as a rehabilitation tool as there is no reliable way to monitor the additional stress placed on the central organs. The current study aimed to determine between-day reliability of central haemodynamic indices using oscillometric pulse wave analysis (PWA) during progressive sub-maximal RT. METHODS: Nineteen healthy young males were tested on 3 different mornings in a fasted state...
December 5, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/29224081/electrochemical-applications-in-metal-bioleaching
#14
Christoph Kurt Tanne, Axel Schippers
Biohydrometallurgy comprises the recovery of metals by biologically catalyzed metal dissolution from solids in an aqueous solution. The application of this kind of bioprocessing is described as "biomining," referring to either bioleaching or biooxidation of sulfide metal ores. Acidophilic iron- and sulfur-oxidizing microorganisms are the key to successful biomining. However, minerals such as primary copper sulfides are recalcitrant to dissolution, which is probably due to their semiconductivity or passivation effects, resulting in low reaction rates...
December 10, 2017: Advances in Biochemical Engineering/biotechnology
https://www.readbyqxmd.com/read/29223653/effects-of-cardiac-rehabilitation-on-heart-rate-recovery-of-patients-undergoing-a-cardiac-rehabilitation-programme-after-acute-coronary-syndrome
#15
Tiffany Astolfi, Fabio Borrani, Milos Savcic, Vincent Gremeaux, Grégoire P Millet
BACKGROUND: An efficient cardiac rehabilitation programme (CRP) can improve the functional ability of patients after acute coronary syndrome (ACS). OBJECTIVE: To examine the effect of a CRP on parasympathetic reactivation and heart rate recovery (HRR) measured after a 6-min walk test (6MWT), and correlation with 6MWT distance and well-being after ACS. METHODS: Eleven normoweight patients after ACS (BMI < 25kg/m2; 10 males; mean [SD] age 61 [9] years) underwent an 8-week CRP...
December 6, 2017: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/29219607/passive-linearization-of-the-magnetic-bunch-compression-using-self-induced-fields
#16
G Penco, E Allaria, I Cudin, S Di Mitri, D Gauthier, S Spampinati, M Trovó, L Giannessi, E Roussel, S Bettoni, P Craievich, E Ferrari
In linac-driven free-electron lasers, colliders, and energy recovery linacs, a common way to compress the electron bunch to kiloampere level is based upon the implementation of a magnetic dispersive element that converts particle energy deviation into a path-length difference. Nonlinearities of such a process are usually compensated by enabling a high harmonic rf structure properly tuned in amplitude and phase. This approach is however not straightforward, e.g., in C-band and X-band linacs. In this Letter we demonstrate that the longitudinal self-induced field excited by the electron beam itself is able to linearize the compression process without any use of high harmonic rf structure...
November 3, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/29214460/blood-flow-restriction-late-in-recovery-after-heavy-resistance-exercise-hampers-muscle-recuperation
#17
Kestutis Bunevicius, Albinas Grunovas, Tomas Venckunas, Kristina Poderiene, Eugenijus Trinkunas, Jonas Poderys
PURPOSE: This study aimed to examine the effect of acute blood flow restriction during the late recovery phase between two resistance exercise bouts on muscular endurance and oxygenation. METHODS: Amateur male middle- and long-distance runners performed two bouts of one-leg dynamic plantar flexion exercise to failure with the load equivalent to 75% of maximum. Subjects were randomly assigned into two experimental groups with thigh occlusion pressure between bouts at either 120 or 200 mmHg with 20 min of passive rest in between, and two control groups without any blood flow restriction separated by either 5 or 20 min of rest...
December 6, 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/29203640/tgf-%C3%AE-induced-proliferative-arrest-mediated-by-trim26-dependent-taf7-degradation-and-its-antagonism-by-myc
#18
Tadashi Nakagawa, Masaki Hosogane, Makiko Nakagawa, Akane Morohoshi, Ryo Funayama, Keiko Nakayama
Recognition of gene promoters by RNA polymerase II is mediated by general transcription factor IID (TFIID), which has been thought to be a static complex and to play a passive role in the regulation of gene expression under the instruction of gene-specific transcription factors. Here we show that transforming growth factor--β (TGF-β) induced degradation of the TFIID subunit TAF7 in cultured mouse mammary epithelial cells and that this effect was required for proliferative arrest in response to TGF-β stimulation...
December 4, 2017: Molecular and Cellular Biology
https://www.readbyqxmd.com/read/29199131/combined-therapy-involving-electroacupuncture-and-treadmill-exercise-attenuates-demyelination-in-the-corpus-callosum-by-stimulating-oligodendrogenesis-in-a-rat-model-of-neonatal-hypoxia-ischemia
#19
Malk Eun Pak, Da Hee Jung, Hong Ju Lee, Myung Jun Shin, Soo-Yeon Kim, Yong Beom Shin, Young Ju Yun, Hwa Kyoung Shin, Byung Tae Choi
We investigated whether electroacupuncture (EA) and treadmill (TM) exercise improve behaviors related to motor and memory dysfunction in a cerebral palsy-like rat model via activation of oligodendrogenesis. A neonatal hypoxia-ischemia model was created using Sprague-Dawley rats (P7), and these underwent EA stimulation and treadmill training from 3 to 5weeks after hypoxia-ischemia induction. EA treatment was delivered via electrical stimulation (2Hz, 1mA) at two acupoints, Baihui (GV20) and Zusanli (ST36). Behavioral tests showed that EA alleviated motor dysfunction caused by hypoxia-ischemia on a rotarod test, and TM exercise alleviated motor and memory dysfunction seen on cylinder and passive avoidance tests...
February 2018: Experimental Neurology
https://www.readbyqxmd.com/read/29195326/multipulse-dynamics-of-a-passively-mode-locked-semiconductor-laser-with-delayed-optical-feedback
#20
Lina Jaurigue, Bernd Krauskopf, Kathy Lüdge
Passively mode-locked semiconductor lasers are compact, inexpensive sources of short light pulses of high repetition rates. In this work, we investigate the dynamics and bifurcations arising in such a device under the influence of time delayed optical feedback. This laser system is modelled by a system of delay differential equations, which includes delay terms associated with the laser cavity and feedback loop. We make use of specialised path continuation software for delay differential equations to analyse the regime of short feedback delays...
November 2017: Chaos
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