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hepatic hemangioma

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https://www.readbyqxmd.com/read/27913123/a-two-stage-surgical-and-endovascular-treatment-of-rare-multiple-aneurysms-of-pancreatic-arteries
#1
Bibek Aryal, Teruo Komokata, Takayuki Ueno, Bunsei Yamamoto, Terutoshi Senokuchi, Hiroshi Yasuda, Mamoru Kaieda, Yutaka Imoto
Aneurysms of pancreatic arteries (PAs) are often found incidentally during evaluation of other abdominal pathology. Aneurysms involving multiple PAs are rarely reported in the literature. In case reports of PA aneurysm, inferior pancreaticoduodenal artery is the usual site of aneurysm occurrence. PA aneurysms can be treated surgically by aneurysm exclusion, excision, and by endovascular techniques. However, no clear consensus exists regarding treatment modality, leaving the surgeon to determine the most appropriate approach bearing in mind their experience, anatomical location of the aneurysm, involved artery and urgency of the procedure...
November 29, 2016: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/27902599/could-adc-values-be-a-promising-diagnostic-criterion-for-differentiating-malignant-and-benign-hepatic-lesions-in-asian-populations-a-meta-analysis
#2
Jing Peng, Jing-Jin Li, Jiang Li, He-Wen Li, Guo-Ping Xu, Rong-Rong Jia, Xue-Ning Zhang, Yang Zhao
BACKGROUND: Liver cancer exhibits geographic and ethnic differences in its prevalence and biology, which implies that it is impractical to develop universal guidelines for all patients. Thus, a meta-analysis was conducted to identify the accuracy of apparent diffusion coefficients (ADCs) for discriminating malignant from benign liver lesions in Asians. METHODS: Eligible studies published in PubMed, Ovid, and Embase/Medline were updated onto October 2014. STATA 12...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27872856/altered-expression-of-epo-might-underlie-hepatic-hemangiomas-in-lrrk2-knockout-mice
#3
Ben Wu, Kaifu Xiao, Zhuohua Zhang, Long Ma
Parkinson's disease (PD) is a severe neurodegenerative disorder caused by progressive loss of dopaminergic neurons in the substantia nigra pars compacta of the midbrain. The molecular mechanism of PD pathogenesis is unclear. Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene are a common genetic cause of familial and sporadic PD. However, studies on LRRK2 mutant mice revealed no visible dopaminergic neuronal loss in the midbrain. While surveying a LRRK2 knockout mouse strain, we found that old animals developed age-dependent hepatic vascular growths similar to cavernous hemangiomas...
2016: BioMed Research International
https://www.readbyqxmd.com/read/27781125/torsion-of-a-giant-pedunculated-hemangioma-of-the-liver-presenting-with-acute-abdomen-a-case-report
#4
Aliasghar Darzi, Hassan Taheri, Sekineh Kamali Ahangar, Alameh Mirzapour Shafiei, Yasser Asghari
INTRODUCTION: Hemangioma is the most common benign tumor of the liver. Most cases are asymptomatic and do not require treatment. A hemangioma can rarely be pedunculated; as a result, it may undergo torsion and infarction, which can make it symptomatic. CASE PRESENTATION: We report the case of a 45-year-old woman with acute abdominal pain due to torsion of a giant pedunculated hepatic hemangioma around its vascular stalk. CONCLUSIONS: Pedunculated hemangioma of the liver is an uncommon benign tumor, a rare differential diagnosis for a mass located in the upper abdomen...
August 2016: Iranian Red Crescent Medical Journal
https://www.readbyqxmd.com/read/27776663/superb-microvascular-imaging-technology-for-ultrasound-examinations-initial-experiences-for-hepatic-tumors
#5
Dong Ho Lee, Jae Young Lee, Joon Koo Han
PURPOSE: To explore whether superb microvascular imaging (SMI) technology could be helpful for the evaluation of hepatic tumors. MATERIALS AND METHODS: Our institutional review board approved this study, and informed consent was obtained from all of the patients. Twenty-three patients with 29 hepatic tumors were enrolled in our study. The tumors consisted of hemangiomas (n=15), focal nodular hyperplasias (FNHs) (n=7), and hepatocellular carcinomas (n=7). All lesions were pathologically (n=2) or radiologically (n=27) confirmed...
November 2016: European Journal of Radiology
https://www.readbyqxmd.com/read/27754755/laparoscopic-liver-resection-and-enucleation-of-liver-hemangioma-with-selective-hepatic-vascular-occlusion-technique-and-indications
#6
Youlong Wang, Wenbin Ji, Xi Zhang, Jingwang Tan
BACKGROUND: Liver resection or enucleation has been the basic treatment for liver hemangioma. However, there were few reports about laparoscopic surgery (LS) of hemangioma. The intention of this study is to explore the indication and efficacy of LS for laparoscopic hepatectomy (LH) and develop an opinion of these modern developments. PATIENTS AND METHODS: Forty-four patients with LH underwent LS, with hemihepatic vascular occlusion (HVO group n = 24) or modified vascular occlusion (MVO group n = 20), and were retrospectively reviewed, including patients' demography, surgical technique, tumor size and location, blood loss, operation time, complications, modes of hepatic vascular occlusion and changes in postoperative liver function, and the difference in patients demography and operative outcome between HVO and MVO groups were compared as well...
October 18, 2016: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/27749413/prostate-specific-membrane-antigen-pet-ct-findings-for-hepatic-hemangioma
#7
Hemant Bhardwaj, Maximilian Stephens, Manoj Bhatt, Paul Anthony Thomas
We report a case of a benign liver hemangioma with intense prostate-specific membrane antigen (PSMA) uptake on Ga PET/CT. A 77-year-old man with prostate adenocarcinoma underwent routine staging with PSMA PET/CT. This revealed an intensely PSMA-avid liver lesion. The known prostate adenocarcinoma was localized and had mild uptake. Diagnostic CT and MRI were characteristic of a hemangioma without interval growth over a 3-month period. PSMA PET/CT is becoming increasingly popular for staging in prostate cancer, and the presence of PSMA uptake in extra-prostatic tumors is being increasingly documented...
December 2016: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/27708485/dwi-adc-in-differentiation-of-benign-from-malignant-focal-liver-lesion
#8
Elma Jahic, Amela Sofic, Azra Husic Selimovic
MATERIAL AND METHODS: The study was of prospective-retrospective character. It was carried out at the AKH in Vienna (Austria), where 100 patients with focal liver lesions were included in the study. All patients underwent the routine MR sequences on appliances 1,5 and 3T (Siemens, Germany): T1, T2, HASTE, VIBE, and a DWI with three b values (b 50, b 300 b 600 s / mm(2)) and ADC map with ROI (regions of interest). The numerical value of ADC map was calculated, where n = 100 liver lesions, by two independent radiologists...
July 16, 2016: Acta Informatica Medica: AIM
https://www.readbyqxmd.com/read/27686480/fine-clinical-differences-between-patients-with-multifocal-and-diffuse-hepatic-hemangiomas
#9
Kai Li, Zuopeng Wang, Yinhua Liu, Wei Yao, Yin Gong, Xianmin Xiao
BACKGROUND: It has been reported that multifocal and diffuse hepatic hemangiomas are true infantile hemangiomas for which a continuum probably exists. We determined the similarities and fine differences between the two types of hemangioma and identified the multifocal subgroup of type, which needs timely treatment. MATERIAL AND METHODS: Twenty-four patients (4 males and 20 females; age 114±142days) with multifocal or diffuse hepatic hemangiomas who were treated between January 2000 and June 2015 were studied...
September 16, 2016: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/27679693/split-bolus-multidetector-row-computed-tomography-technique-for-characterization-of-focal-liver-lesions-in-oncologic-patients
#10
Michele Scialpi, Luisa Pierotti, Sabrina Gravante, Alberto Rebonato, Irene Piscioli, Alfredo D'Andrea, Raffaele Schiavone, Barbara Palumbo
BACKGROUND: In oncologic patients, the liver is the most common target for metastases. An accurate detection and characterization of focal liver lesions in patients with known primary extrahepatic malignancy are essential to define management and prognosis. OBJECTIVES: To assess the diagnostic accuracy of the split-bolus multidetector-row computed tomography (MDCT) protocol in the characterization of focal liver lesions in oncologic patients. PATIENTS AND METHODS: We retrospectively analyzed the follow-up split-bolus 64-detector row CT protocol in 36 oncologic patients to characterize focal liver lesions...
April 2016: Iranian Journal of Radiology: a Quarterly Journal Published By the Iranian Radiological Society
https://www.readbyqxmd.com/read/27664970/intravoxel-incoherent-motion-diffusion-weighted-imaging-for-characterizing-focal-hepatic-lesions-correlation-with-lesion-enhancement
#11
In Young Choi, Seung Soo Lee, Yu Sub Sung, Hyunhee Cheong, Hoyoung Lee, Jae Ho Byun, So Yeon Kim, So Jung Lee, Yong Moon Shin, Moon-Gyu Lee
PURPOSE: To evaluate the value of intravoxel incoherent motion (IVIM) parameters for characterizing focal hepatic lesions, and to assess the correlation between IVIM parameters and arterial nodule enhancement. MATERIALS AND METHODS: We retrospectively evaluated 161 lesions (91 hepatocellular carcinomas [HCCs], 27 intrahepatic cholangiocarcinomas [IHCCs], 20 hemangiomas, 9 combined hepatocellular-cholangiocarcinomas, 9 metastases, and 5 other tumors) in 161 patients (105 men and 56 women; mean age, 56...
September 24, 2016: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/27620909/pure-laparoscopic-right-hepatectomy-for-giant-hemangioma-using-anterior-approach
#12
Seok-Hwan Kim, Ki-Hun Kim, Varvara A Kirchner, Sang-Kyung Lee
BACKGROUND: Laparoscopic major hepatectomy remains a challenging procedure [1, 2]. In the case of giant tumors in the right liver, conventional approach (complete mobilization of the right liver before parenchymal transection) could be dangerous during mobilization because of large volume and weight [3, 4]. We present the case of a pure laparoscopic right hepatectomy for a giant hemangioma using an anterior approach. METHODS: We achieved the informed consent with this patient and approved by the Ethics Committee of the Asan Medical Center...
September 12, 2016: Surgical Endoscopy
https://www.readbyqxmd.com/read/27614046/igf2-is-up-regulated-by-epigenetic-mechanisms-in-hepatocellular-carcinomas-and-is-an-actionable-oncogene-product-in-experimental-models
#13
Iris Martinez-Quetglas, Roser Pinyol, Daniel Dauch, Sara Torrecilla, Victoria Tovar, Agrin Moeini, Clara Alsinet, Anna Portela, Leonardo Rodriguez-Carunchio, Manel Solé, Amaia Lujambio, Augusto Villanueva, Swan Thung, Manel Esteller, Lars Zender, Josep M Llovet
BACKGROUND & AIMS: Effective treatments are urgently needed for hepatocellular carcinoma (HCC), which is usually diagnosed at advanced stages. Signaling via the insulin-like growth factor (IGF) pathway is aberrantly activated in HCC by IGF2 overexpression. We aimed to elucidate the mechanism of IGF2 overexpression and its oncogenic activities and evaluate the anti-tumor effects of reducing IGF2 signaling. METHODS: We obtained 228 HCC samples from patients who underwent liver resection, 168 paired non-tumor adjacent cirrhotic liver samples, and 10 non-tumor liver tissues from patients undergoing resection for hepatic hemangioma...
December 2016: Gastroenterology
https://www.readbyqxmd.com/read/27610342/history-of-the-infantile-hepatic-hemangioma-from-imaging-to-generating-a-differential-diagnosis
#14
REVIEW
Maria Gnarra, Gerald Behr, Alison Kitajewski, June K Wu, Sudha A Anupindi, Carrie J Shawber, Nick Zavras, Dimitrios Schizas, Chris Salakos, Konstantinos P Economopoulos
We aim to provide an up-to-date summary of infantile hepatic hemangioma (IHH) and its misnomers and to dialectically present the differential diagnosis of these rare entities of the liver. Eligible peer-reviewed articles on hepatic infantile hemangiomas, published between 2000 and 2015, were reviewed for this study. IHH is the most common hepatic vascular tumor in children. Once a liver mass is identified in an infant, the differential diagnosis ranges from vascular malformations to benign and malignant tumors including mesenchymal hamartoma, hepatoblastoma, metastatic neuroblastoma, so careful physical examination, imaging studies, and, if indicated, tumor markers and biopsy, are of pivotal importance to ascertain the correct diagnosis...
August 8, 2016: World Journal of Clinical Pediatrics
https://www.readbyqxmd.com/read/27607320/congenital-hemangiomas
#15
Christina Boull, Sheilagh M Maguiness
Congenital hemangiomas are rare solitary vascular tumors that do not proliferate after birth. They are characterized as either rapidly involuting congenital hemangiomas (RICHs) or noninvoluting congenital hemangiomas (NICHs) based on their clinical progression. NICHs have no associated complications, but are persistent. RICH, while usually asymptomatic, may ulcerate or bleed early in their presentation, but involute quickly during the first few months of life. Hepatic RICHs are not associated with cutaneous RICHs, but may result in high-output cardiac failure due to arteriovenous or portovenous shunting...
September 2016: Seminars in Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/27607318/infantile-hemangiomas-complications-and-treatments
#16
Carol Erin Cheng, Sheila Fallon Friedlander
Infantile hemangiomas (IHs) are the most common vascular tumors of infancy. While the majority regress without the need for intervention, approximately 10%, often site dependent, can cause serious complications and require treatment. IH complications can be categorized as life threatening, obstructive, ulcerative or disfiguring. Life threatening complications include airway and hepatic IHs. Functional complications obstructing vital structures or impairing function include periocular, nasal, labial, parotid, auricular, and breast IHs...
September 2016: Seminars in Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/27574349/enucleation-is-better-for-a-giant-hemangioma-proximal-to-the-hepatic-portal-vascular-structures
#17
Chuan-Xing Wu, Wan-Yuan Bao, Feng Zhu
The aim of this study is to compare the effect of liver enucleation with resection of a giant hemangioma proximal to the hepatic portal vascular structures. From 2008 to 2014, 53 patients with giant hemangiomas proximal to the hepatic portal vascular structures underwent surgery in our hospital by the same surgical team. The indications for surgery included a tumor size greater than 8 cm, a middle size greater than 4 cm but with abdominal pain, a rapidly increased tumor size with uncertain malignancy, or tumor rupture...
August 2016: Indian Journal of Surgery
https://www.readbyqxmd.com/read/27530723/clinical-features-and-management-of-multifocal-hepatic-hemangiomas-in-children-a-retrospective-study
#18
Yi Ji, Siyuan Chen, Bo Xiang, Zhicheng Xu, Xiaoping Jiang, Xingtao Liu, Qi Wang, Guoyan Lu, Li Yang
Multifocal hepatic hemangioma (MHH) is a benign hepatic tumor that is commonly diagnosed in children with multiple cutaneous infantile hemangiomas (IHs). We present a review of all children with MHH at our institutions. Of the 42 patients, the median age at presentation of MHH was 2.5 months. Thirty-six (85.7%) patients had cutaneous IHs. Twelve (28.6%) patients were symptomatic at presentation. There was no significant association between the number of hepatic hemangiomas and the number of cutaneous IHs. Fourteen (33...
2016: Scientific Reports
https://www.readbyqxmd.com/read/27489679/transumbilical-glove-port-a-cost-effective-method-for-single-incision-laparoscopic-hepatectomy
#19
Ryohei Miyata, Noriaki Kameyama, Masato Tomita, Hiroaki Mitsuhashi, Shigeaki Baba, Ryusuke Amemiya, En Amada
OBJECTIVES: Emerging concepts of "reduced port surgery" have gained considerable attention from laparoscopic surgeons, including the field of liver resection. To date, 86 cases of single-incision laparoscopic hepatectomy (SILH) have been reported, with commercially available access devices being used in most of these cases. We report herein a use of homemade transumbilical glove port for SILH. METHODS: A 39-year-old woman represented giant hepatic hemangioma (9-cm in size) located at the left lateral segment (S2/3)...
2015: SAGE open medical case reports
https://www.readbyqxmd.com/read/27488094/hepatocellular-carcinoma-developed-in-a-living-donor-after-left-lobe-donation-a-case-for-caution
#20
Toru Ikegami, Tomoharu Yoshizumi, Junji Kawasaki, Tomonari Shimagaki, Hideaki Uchiyama, Yuji Soejima, Yoshihiko Maehara
Although it has been recognized that those who are positive for anti-hepatitis B core antibody (anti-HBcAb) and negative for hepatitis B surface antigen (HBsAg) with normal liver function could be donors for living donor liver transplantation under appropriate prophylaxis, the negative impact of positive HBcAb on such donors themselves has not been reported. We present a case of a living donor with positive HBcAb, who donated his left lobe for his sister with unresectable giant hepatic hemangioma, and the donor himself developed a de novo hepatocellular carcinoma (HCC) 10 years after donation...
August 2, 2016: Hepatology Research: the Official Journal of the Japan Society of Hepatology
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