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hepatic hemangioma

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https://www.readbyqxmd.com/read/29674973/hepatic-hemangiomas-alter-morphometry-and-impair-hemodynamics-of-the-abdominal-aorta-and-primary-branches-from-computer-simulations
#1
Xiaoping Yin, Xu Huang, Qiao Li, Li Li, Pei Niu, Minglu Cao, Fei Guo, Xuechao Li, Wenchang Tan, Yunlong Huo
Background: The formation of hepatic hemangiomas (HH) is associated with VEGF and IL-7 that alter conduit arteries and small arterioles. To our knowledge, there are no studies to investigate the effects of HH on the hemodynamics in conduit arteries. The aim of the study is to perform morphometric and hemodynamic analysis in abdominal conduit arteries and bifurcations of HH patients and controls. Methods: Based on morphometry reconstructed from CT images, geometrical models were meshed with prismatic elements for the near wall region and tetrahedral and hexahedral elements for the core region...
2018: Frontiers in Physiology
https://www.readbyqxmd.com/read/29596087/analysis-of-follicle-stimulating-hormone-receptor-in-infantile-hemangioma
#2
Reid A Maclellan, Dennis J Konczyk, Jeremy A Goss, Arin K Greene
INTRODUCTION: The life cycle of infantile hemangioma (IH) and secretion of follicle-stimulating hormone (FSH) are identical. We previously have shown that IH contains the FSH receptor (FSHR). The purpose of this study was to identify which cell type(s) in IH expresses FSHR. METHODS: Human proliferating IH tissues obtained during a clinically indicated surgical procedure were used. Paraffin sections and isolated cell populations (endothelial, pericyte, stem cell) were subjected to immunofluorescence for FSHR...
March 29, 2018: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/29594465/interpreting-body-mri-cases-classic-findings-in-abdominal-mri
#3
REVIEW
Leann Kania, Flavius Guglielmo, Donald Mitchell
Few things in radiology are "pathognomonic" in their appearance or presentation. However, having an awareness of those findings which are specific to a certain entity is important when interpreting imaging studies. These classic findings can be identified with many imaging modalities, but no modality provides as many recognizable observations as an MRI. This results from the large variety of pulse sequences that provide high contrast resolution, prior to and following contrast administration. In this article, the most classically recognized abdominal findings are presented including the following: Liver: Cyst, hemangioma, focal nodular hyperplasia, hepatic adenoma, hemosiderosis, hepatocellular carcinoma...
March 28, 2018: Abdominal Radiology
https://www.readbyqxmd.com/read/29576414/imaging-and-pathologic-findings-of-hepatic-small-vessel-hemangioma
#4
Balasubramanya Rangaswamy, Marta Minervini, Mitchell Tublin, Biatta Sholosh, Anil K Dasyam
Hepatic small vessel hemangioma represents a distinct yet very rare pathologic entity of the liver. The entity has also been in the past referred to as adult capillary hemangioma of the liver and congenital noninvoluting hemangioma. Imaging findings are not definitive and biopsy or resection is ultimately necessary. Pathologically these represent vasoformative abnormalities with infiltrative margins that can potentially mimic hepatic angiosarcoma. Immunohistochemistry can help differentiate hepatic small vessel hemangioma from angiosarcoma...
February 14, 2018: Current Problems in Diagnostic Radiology
https://www.readbyqxmd.com/read/29568758/surgical-technique-and-clinical-analysis-of-twelve-cases-of-isolated-laparoscopic-resection-of-the-hepatic-caudate-lobe
#5
Bin Jin, Zhengchen Jiang, Sanyuan Hu, Gang Du, Binyao Shi, Du Kong, Jinhuan Yang
Objective: To describe the surgical procedures of laparoscopic caudate lobectomy and analyze its clinical efficiency for treating cancer. Methods: Twelve consecutive patients of hepatocellular carcinoma, hepatic hemangioma, and focal nodular hyperplasia who received laparoscopic caudate lobectomy in Qilu Hospital of Shandong University from January 2013 to January 2017 were included in this study. The clinical data, intraoperative parameters, and postoperative outcomes were assessed...
2018: BioMed Research International
https://www.readbyqxmd.com/read/29560099/atypical-appearance-of-hepatic-hemangiomas-with-contrast-enhanced-ultrasound
#6
Min Huang, Qiyu Zhao, Fen Chen, Qihan You, Tian'an Jiang
To describe the atypical enhancement pattern of hepatic hemangiomas on contrast-enhanced sonography. 22 patients with hepatic hemangiomas that were atypical on contrast-enhanced ultrasound were included in the study, all of them were confirmd by biopsy or surgery pathology. Atypical appearance of hepatic hemangiomas on contrast-enhanced ultrasound were divided into seven subtypes: (i) peripheral nodular enhancement in the arterial phase with centripedal filling, hypoechoic change in the delayed phase; (ii) peripheral circular enhancement; (iii) peripheral nodular enhancement; (iv) none enhancement; (v) septal enhancement; (vi) a central enhancing focus in the arterial phase, followed by a centrifugal enhancement in the portal venous phase, hypoechoic change in the delayed phase; (vii) slowly spoke wheel enhancement...
February 27, 2018: Oncotarget
https://www.readbyqxmd.com/read/29537380/resolution-of-consumptive-hypothyroidism-secondary-to-infantile-hepatic-hemangiomatosis-with-combination-propranolol-and-levothyroxine
#7
V Campbell, R Beckett, N Abid, S Hoey
Infantile hepatic hemangiomas (IHH), particularly of the diffuse subtype, can in severe cases be associated with hepatic and cardiac failure, compartment syndrome, and consumptive hypothyroidism. Early recognition and treatment of these pathologies is paramount in order to minimise the risk of longterm sequelae. We report an interesting case of a female infant who presented with systemic compromise, in the absence of large or obvious cutaneous infantile hemangiomas (IH). Imaging identified innumerable hepatic hemangiomas, consistent with diffuse infantile hepatic hemangiomatosis...
February 28, 2018: Journal of Clinical Research in Pediatric Endocrinology
https://www.readbyqxmd.com/read/29488123/surgical-management-of-giant-hepatic-hemangioma-single-center-s-experience-with-144-patients
#8
Mohamed Abdel Wahab, Ayman El Nakeeb, Mahmoud Abdelwahab Ali, Youssef Mahdy, Ahmed Shehta, Mohamed Abdulrazek, Mohamed El Desoky, Rihame Abdel Wahab
BACKGROUND: Hepatic hemangioma (HH) is the most common benign solid tumor of the liver. The aim of this study is to review our experiences of surgical treatment for giant HH and to show the impact of HH size and type of surgical resection on surgical outcomes. PATIENTS AND METHODS: This is a retrospective study of the cases who underwent surgery for giant HH during the period from January 2000 to April 2017. RESULTS: Elective surgery was performed for 144 patients who had giant HH...
February 27, 2018: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/29469049/safety-and-efficacy-of-laparoscopic-radiofrequency-ablation-for-hepatic-hemangiomas-a-multicenter-retrospective-study
#9
Shun-Qian Wen, Ming Wan, Kai-Ming Len, Qiu-Hui Hu, Xue-Yi Xie, Qing Wu, Guan-Qun Liao
INTRODUCTION: Radiofrequency ablation (RFA) is an effective and minimally invasive technique for the management of hepatic hemangiomas (HHs). This study aims to assess the safety and efficacy of laparoscopic RFA for HHs. MATERIAL AND METHODS: Forty-four patients with 50 hepatic hemangiomas (5-10 cm in diameter) undergoing laparoscopic RFA from January 2012 to May 2015 at three tertiary hospitals in China were retrospectively analyzed. RESULTS: Thirty-three patients with subcapsular hemangiomas were treated with a laparoscopic approach, and 11 patients with lesions in the liver parenchyma were treated with a combined laparoscopy and an ultrasound-guided percutaneous approach...
March 1, 2018: Annals of Hepatology
https://www.readbyqxmd.com/read/29434910/application-values-of-3-0t-magnetic-resonance-diffusion-weighted-imaging-for-distinguishing-liver-malignant-tumors-and-benign-lesions
#10
Ruibin Li, Guangyao Wu, Rui Wang
The aim of the present study was to investigate the significance and values of 3.0T diffusion weighted imaging (DWI) to differentially diagnose benign and malignant space-occupying liver lesions. A total of 91 patients with liver space-occupying lesions (145 lesions) were admitted into Zhongnan Hospital of Wuhan University (Wuhan, China) from November 2015 to May 2016. Routine scanning, DWI and high-resolution T2-weighted imaging using spin-echo echo-planar imaging were performed on all patients, to compare the apparent diffusion coefficient (ADC) values of three regions of interest in lesions with normal liver tissue...
February 2018: Oncology Letters
https://www.readbyqxmd.com/read/29433744/chemotherapy-induced-response-of-liver-hemangiomas-in-a-patient-with-a-germ-cell-tumor-a-case-report
#11
N Arévalo, R Méndez, A Manzano
Liver hemangiomas are the most common benign primary tumors of the liver. Due to their high prevalence, incidental finding of hemangiomas during radiological workup of oncologic patients is not uncommon. We present the case of a patient diagnosed of an ovarian immature teratoma and hepatic lesions with typical radiological appearance of hemangiomas that decreased in size during adjuvant chemotherapy with BEP regimen (cisplatin, etoposide and bleomycin). Chemotherapy-induced shrinkage of hepatic hemangiomas can mimic the response of liver metastases to chemotherapy and may induce erroneous interpretations...
February 9, 2018: Radiología
https://www.readbyqxmd.com/read/29390333/atypical-hemangioma-mimicking-mixed-hepatocellular-cholangiocarcinoma-case-report
#12
Shengzhang Lin, Lele Zhang, Mengxia Li, Qiyang Cheng, Liang Zhang, Shusen Zheng
RATIONALE: Hemangioma of the liver is a benign hepatic tumor, more common in women than in men, which is typically asymptomatic, solitary, and incidentally discovered. Atypical hemangioma is a variant of hepatic hemangioma with atypical imaging finding features on CT and MRI that can be confused with hepatocellular carcinoma (HCC), intrahepatic cholangiocarcinoma (ICC) and mixed hepatocellular cholangiocarcinoma (HCC-CC). PATIENT CONCERNS: We report a case of atypical hepatic hemangioma mimicking HCC-CC: A 59-year-old man was referred to our hospital for a hepatic lesion that was 4...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29383241/co-existing-infantile-hepatic-hemangioma-and-mesenchymal-hamartoma-in-a-neonate
#13
Nicolas Berte, Alya Filfilan, Laurence Mainard, Ludovic Mansuy, Jean-Louis Lemelle
Infantile hepatic hemangioma (IHH) and mesenchymal hamartoma (MH) form the first and second most common benign hepatic tumors in children. In this case report, we present a newborn child in whom a growing hepatic mass was discovered at the age of 7 days. She suffered also from anemia, respiratory and renal failure. No signs of heart disease or cutaneous lesions were detected. Alpha-fetoprotein was elevated for her age (3562.2 ng/ml). Imaging studies showed multifocal large cystic lesions associated with heterogeneous small solid lesions with arterial enhancement of the liver...
January 2018: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/29381980/circulating-d-dimer-level-correlates-with-disease-characteristics-in-hepatoblastoma-patients
#14
BinBin Zhang, GongBao Liu, XiangQi Liu, Shan Zheng, Kuiran Dong, Rui Dong
OBJECTIVES: Hepatoblastoma (HB) is the most common pediatric liver malignancy, typically affecting children within the first 4 years of life. However, only a few validated blood biomarkers are used in clinical evaluation. The current study explored the clinical application and significance of D-dimer levels in patients with HB. METHOD: Forty-four patients with HB were included in this retrospective study. D-dimer and plasma fibrinogen levels were examined, and their correlation with other clinical features was analyzed...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29381955/spontaneous-internal-hemorrhage-of-a-giant-hepatic-hemangioma-a-case-report
#15
Fulong Hao, Xiaoli Yang, Yinsheng Tian, Wenping Wang, Minggang Ge
RATIONALE: Hepatic hemangioma, a benign liver tumor, can rarely spontaneously rupture and hemorrhage, which is then associated with significant mortality. The diagnosis of internal hemorrhage is challenging and the management is disputed. PATIENT CONCERNS: We describe the case of a 52-year-old female patient with chief complaints of fever and anemia, with no history of recent trauma. DIAGNOSES: Ultrasound suggested the possibility of a liver abscess and computed tomography (CT) examination revealed a giant space occupying lesion (SOL) (approximately 16 cm) in the right hepatic lobe, indicating a hepatic tumor or abscess...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29366622/resection-of-the-largest-reported-hepatic-small-vessel-neoplasm
#16
Sarah Walcott-Sapp, Ephraim Tang, Sanjay Kakar, Jian Shen, Paul Hansen
Hepatic small vessel neoplasm (HSVN) is a recently described vascular neoplasm of the adult liver. The neoplastic cells are positive for markers of vascular lineage (CD31, CD34, FLI-1). The distinctive morphology and infiltrative borders separate HSVN from benign vascular tumors such as cavernous hemangioma, while lack of atypical morphologic features, low to absent mitotic activity and low proliferation index distinguish it from malignant vascular tumors such as epithelioid hemangioendothelioma and angiosarcoma...
January 20, 2018: Human Pathology
https://www.readbyqxmd.com/read/29357040/hepatic-cavernous-hemangiomas-long-term-5-years-follow-up-changes-on-contrast-enhanced-dynamic-computed-tomography-or-magnetic-resonance-imaging-and-determinant-factors-of-the-size-change
#17
Jiae Choi, Jeong-Sik Yu, Eun-Suk Cho, Joo Hee Kim, Jae-Joon Chung
PURPOSE: To investigate the very long-term (> 5 years) follow-up changes of hepatic cavernous hemangiomas and to evaluate possible determinant factors for the changes. MATERIALS AND METHODS: Among 1115 consecutive patients suspected of having hepatic hemangiomas based on imaging features, 101 patients with comparable computed tomography or magnetic resonance imaging data during a 5-year follow-up interval in the Picture Archiving and Communication System were analyzed...
May 2018: La Radiologia Medica
https://www.readbyqxmd.com/read/29356748/primary-spleen-angiosarcoma-with-concomitant-hepatic-hemangiomas-on-18f-fdg-pet-ct
#18
Kun Zheng, Yu Liu, Ruixue Cui, Fang Li
A staging FDG PET/CT was performed for a 43-year-old woman who was suspected to have splenic malignancy with multiple hepatic metastases revealed on CT images. The PET/CT images showed the masses and nodules of spleen had mildly increased uptake of FDG, whereas the uptake by the hepatic lesions was slightly higher. However, the pathologic evaluation demonstrated that splenic lesion was malignant as angiosarcoma, but the hepatic lesions were benign as hemangiomas.
March 2018: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/29334905/efficacy-comparison-of-multi-phase-ct-and-hepatotropic-contrast-enhanced-mri-in-the-differential-diagnosis-of-focal-nodular-hyperplasia-a-prospective-cohort-study
#19
Tomasz K Nowicki, Karolina Markiet, Ewa Izycka-Swieszewska, Katarzyna Dziadziuszko, Michal Studniarek, Edyta Szurowska
BACKGROUND: Different clinical behaviour influences the importance of differentiating focal nodular hyperplasia (FNH) from other focal liver lesions (FLLs). The aim of this study was to compare the efficacy of contrast-enhanced CT and MRI in the diagnosis of FNH. METHODS: 157 patients with equivocal FLLs detected in ultrasonography subsequently underwent multi-phase CT and MRI with the use of hepatotropic contrast agent (Gd-BOPTA) in a 1.5 T scanner. Examinations were evaluated by three independent readers...
January 15, 2018: BMC Gastroenterology
https://www.readbyqxmd.com/read/29323060/spectrum-of-hepatobiliary-cystic-lesions-a-7-year-experience-at-a-tertiary-care-referral-center-in-north-india-and-review-of-literature
#20
Prasenjit Das, Pragya Sharma, Tripti Nakra, Shouriyo Ghosh, Rajni Yadav, Brijnandan Gupta, Gaurav Khanna, K S Madhusudhan, Rajesh Panwar, M K Anoop, Ragini Kilambi, Anand N Singh, Nihar R Dash, Sujoy Pal, Siddhartha Datta Gupta
CONTEXT: Cysts arising from the hepatobiliary tree are a group of heterogeneous lesions with regard to pathogenesis, clinical presentation, and radiological finding. They can be intrahepatic or extrahepatic, developmental, secondary to infective/inflammatory etiologies, as well as neoplastic. This study was conducted to determine the spectrum of hepatobiliary cysts in surgically intervened cases, with regard to their prevalence, histological spectrum, and clinicoradiological correlation, wherever possible...
October 2017: Indian Journal of Pathology & Microbiology
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