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hepatic hemangioma

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https://www.readbyqxmd.com/read/28521077/clinical-case-series-of-pediatric-hepatic-angiosarcoma
#1
Kalee L Grassia, Caitlin M Peterman, Ionela Iacobas, Judith F Margolin, Ewa Bien, Bhavna Padhye, Rebecka L Meyers, Denise M Adams
Hepatic angiosarcoma is a rare, aggressive, malignant neoplasm with fewer than 50 cases reported in children. Prognosis is poor, with a minority surviving beyond 2 years after diagnosis. We report eight cases of pediatric hepatic angiosarcoma, diagnosed at a mean age of 3 years. Seven were initially diagnosed with an infantile hepatic hemangioendothelioma (IHHE) or hemangioma and the eighth with a "vascular tumor." Two patients, who received liver transplant, survived. We suggest hepatic hemangiomas can rarely transform into angiosarcomas and a subset of IHHEs (Type II) are actually a low-grade form of angiosarcoma rather than a benign lesion...
May 18, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28516570/proposal-of-size-based-surgical-indication-criteria-for-liver-hemangioma-based-on-a-nationwide-survey-in-japan
#2
Yoshihiro Sakamoto, Norihiro Kokudo, Takeyuki Watadani, Junji Shibahara, Masakazu Yamamoto, Hiroki Yamaue
BACKGROUND: Surgical indications for liver hemangioma remain unclear. METHODS: Of 510 patients undergoing surgical resection for liver hemangioma in 118 Japanese centers between 1998 and 2012, abdominal symptoms, diagnostic accuracy, and surgical outcomes were analyzed to propose size-based surgical indications. Patients were classified into four groups based on tumor size: Group A) ≤5 cm (n = 122, 24%), B) 5-10 cm (n = 164, 32%), C) 10-15 cm (n = 124, 24%), and D) >15 cm (n = 100, 20%)...
May 17, 2017: Journal of Hepato-biliary-pancreatic Sciences
https://www.readbyqxmd.com/read/28489163/hypervascular-liver-lesions-in-radiologically-normal-liver
#3
Enio Campos Amico, José Roberto Alves, Dyego Leandro Bezerra de Souza, Fellipe Alexandre Macena Salviano, Samir Assi João, Adriano de Araújo Lima Liguori
Background: The hypervascular liver lesions represent a diagnostic challenge. Aim: To identify risk factors for cancer in patients with non-hemangiomatous hypervascular hepatic lesions in radiologically normal liver. Method: This prospective study included patients with hypervascular liver lesions in radiologically normal liver. The diagnosis was made by biopsy or was presumed on the basis of radiologic stability in follow-up period of one year...
January 2017: Arquivos Brasileiros de Cirurgia Digestiva: ABCD, Brazilian Archives of Digestive Surgery
https://www.readbyqxmd.com/read/28483013/value-of-texture-feature-analysis-in-the-differential-diagnosis-of-hepatic-cyst-and-hemangioma-in-magnetic-resonance-imaging
#4
Botao Wang, Gang Liu, Wenping Fan, Xiaohuan Zhang, Yuhong Lu, Zhiye Chen
Objective To investigate the difference of texture on conventional T2-weighted image (T2WI) between hepatic cyst and hepatic hemangioma. Methods All the subjects included 156 patients with hepatic cyst [A group:100 cases with equi or low signal on diffusion weighted imaging (DWI);B group:56 cases with high signal on DWI] and 100 patients with hemangioma (C group). Conventional magnetic resonance imaging T2WI,DWI and dynamic contrast enhancement were performed on all the patients,and the texture analysis was applied with the images of T2WI,and the texture parameters included angular second moment,contrast,correlation,inverse difference moment,and entropy...
April 20, 2017: Zhongguo Yi Xue Ke Xue Yuan Xue Bao. Acta Academiae Medicinae Sinicae
https://www.readbyqxmd.com/read/28462238/peritumoral-hyperplasia-in-hepatic-sclerosed-hemangioma
#5
Seitarou Shimada, Kazuto Tajiri, Hayato Baba, Masami Minemura, Koichi Tsuneyama, Masayuki Nakano, Toshiro Sugiyama
Peritumoral hyperplasia (PTH) is a hyperplastic lesion located around hypervascular tumors. Hepatic sclerosed hemangioma is a very rare form of hemangioma with sclerotic changes and is distinct from sclerosing hemangioma. We present a patient with non-alcoholic steatohepatitis-induced cirrhosis who presented with a hypervascular tumor. The tumor showed atypical findings of hemangioma and was treated with surgical resection because hepatic malignancy could not be ruled out. Histopathologic examination revealed the tumor was a sclerosed hemangioma with PTH...
2017: ACG Case Reports Journal
https://www.readbyqxmd.com/read/28454487/diffusion-kurtosis-imaging-of-the-liver-at-3-tesla-in%C3%A2-vivo-comparison-to-standard-diffusion-weighted-imaging
#6
Johannes Budjan, Elke A Sauter, Frank G Zoellner, Andreas Lemke, Jens Wambsganss, Stefan O Schoenberg, Ulrike I Attenberger
Background Functional techniques like diffusion-weighted imaging (DWI) are gaining more and more importance in liver magnetic resonance imaging (MRI). Diffusion kurtosis imaging (DKI) is an advanced technique that might help to overcome current limitations of DWI. Purpose To evaluate DKI for the differentiation of hepatic lesions in comparison to conventional DWI at 3 Tesla. Material and Methods Fifty-six consecutive patients were examined using a routine abdominal MR protocol at 3 Tesla which included DWI with b-values of 50, 400, 800, and 1000 s/mm(2)...
January 1, 2017: Acta Radiologica
https://www.readbyqxmd.com/read/28429345/a-peculiar-case-of-diffuse-hemangiomatosis-of-the-left-hepatic-lobe-in-an-asymptomatic-adult-patient-case-report-and-literature-review
#7
A Guerra, A Infante, E Rinninella, I Spinelli, M A Mazziotti, A M De Gaetano, M Pompili, L Bonomo
We report a rare case of diffuse hepatic hemangiomatosis (DHH) of the left hepatic lobe coexistent with giant hepatic hemangioma and without extra-hepatic involvement in an asymptomatic adult patient. Liver hemangiomas are the most common benign liver tumors. However, DHH without extra-hepatic involvement has rarely been reported in adults. Furthermore, giant hepatic hemangioma coexistent with DHH is even uncommon, although an association between hemangiomatosis and giant hepatic hemangiomas may be supposed...
April 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28424986/extremely-giant-liver-hemangioma-50%C3%A2-cm-with-kasabach-merritt-syndrome
#8
Zhiying Yang, Haidong Tan, Xiaolei Liu, Yongliang Sun
A 33-year-old male has been found with a giant liver hemangioma of initial size 29 cm for 5 years. He received arterial embolization twice in order to shrink the tumor; however, no effect was obtained. The tumor had rapidly grown to 50 cm and caused abnormalities in the hematological and coagulative systems. Preoperative computed tomography revealed that the right hepatic vein, right hepatic artery, and right portal vein were not involved by the hemangioma. Resection of the giant liver hemangioma was successfully performed after intraoperative intentional bloodletting with concurrent blood salvage...
April 19, 2017: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/28420821/use-of-liothyronine-without-levothyroxine-in-the-treatment-of-mild-consumptive-hypothyroidism-caused-by-hepatic-hemangiomas
#9
Shinji Higuchi, Masaki Takagi, Yukihiro Hasegawa
There have been reports of the use of levothyroxine or levothyroxine plus liothyronine for consumptive hypothyroidism caused by hepatic hemangiomas. Administration of levothyroxine without liothyronine can be inadequate to maintain normal levels of both free T3 and free T4 in some patients. However, there is no report of treatment with liothyronine plus propranolol. We herein present a case in which we used liothyronine therapy for multifocal hepatic hemangiomas in a Japanese patient with low free T3 and normal free T4 levels...
April 18, 2017: Endocrine Journal
https://www.readbyqxmd.com/read/28413654/hepatic-perivascular-epithelioid-cell-neoplasm-a-clinical-and-pathological-experience-in-diagnosis-and-treatment
#10
Wenying Chen, Yeqing Liu, Yanyan Zhuang, Juanfei Peng, Fengting Huang, Shineng Zhang
Hepatic perivascular epithelioid cell neoplasm (PEComa) is a rare type of neoplasm derived from mesenchymal tumors that is often misdiagnosed as hepatocellular carcinoma (HCC), hepatic hemangioma or other liver malignancies. The clinical and histological characteristics of PEComa have yet to be fully documented. To optimize the diagnosis and treatment of the disease, a retrospective analysis was performed to investigate the clinicopathological characteristics of 7 patients diagnosed with hepatic PEComa in the Sun Yat-Sen Memorial Hospital between January 2004 and December 2015...
April 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/28402071/successful-use-of-propranolol-for-congenital-hepatic-hemangioma-with-kasabach-merritt-phenomenon
#11
Yuta Kawahara, Hitomi Nijima, Yume Suzuki, Rieko Furukawa, Akira Morimoto
No abstract text is available yet for this article.
April 12, 2017: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/28395113/a-novel-role-for-crtc2-in-hepatic-cholesterol-synthesis-via-srebp-2
#12
Yujie Li, Yongfeng Song, Meng Zhao, Yanjing Guo, Chunxiao Yu, Wenbin Chen, Shanshan Shao, Chao Xu, Xinli Zhou, Lifang Zhao, Zhenhai Zhang, Tao Bo, Yu Xia, Christopher G Proud, Xuemin Wang, Li Wang, Jiajun Zhao, Ling Gao
Cholesterol synthesis is regulated by the transcription factor SREBP-2 and its target gene 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR), which is the rate-limiting enzyme in cholesterol synthesis. CREB-regulated transcription coactivator (CRTC) 2 is the master regulator of glucose metabolism. However, the effect of CRTC2 on cholesterol and its potential molecular mechanism remain unclear. Here, we demonstrated that CRTC2 expression and the liver cholesterol content were increased in patients with high serum cholesterol levels who underwent resection of liver hemangiomas, as well as in mice fed a 4% cholesterol diet...
April 10, 2017: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
https://www.readbyqxmd.com/read/28302004/a-new-perspective-for-infantile-hepatic-hemangioma-in-the-age-of-propranolol-experience-at-baskent-university
#13
Faik Sarıalioğlu, Nalan Yazıcı, Ayşe Erbay, Fatih Boyvat, Şenay Demir, Figen Özçay, Nihal Uslu
Propranolol was first used in 2008 to treat hemangioma; its efficacy and safety have since changed the classical treatment indications. Infantile hepatic hemangioma presents as a spectrum of clinical conditions varying from simple asymptomatic lesions to lethal complications. Tufted hemangioma and Kaposiform hemangioendothelioma are congenital vascular tumors that lead to Kasabach-Merritt syndrome. Hemangiomas, like pure arteriovenous malformations, can cause hyperdynamic heart failure, and diffuse nodular-type hemangiomas can present with hypothyroidism...
March 2017: Experimental and Clinical Transplantation
https://www.readbyqxmd.com/read/28225491/rupture-of-hepatic-hemangioma-with-hemoperitoneum-due-to-spontaneous-gallbladder-perforation-a-unique-case-report
#14
Qing-Hong Ke, Chun-Jun Zhang, Hai-Feng Huang
INTRODUCTION: Hemangiomas are common benign tumors of the liver. Spontaneous rupture is a rare complication, occurring most commonly in giant hemangiomas. Rupture of a hemangioma with hemoperitoneum is a serious development and can be fatal if not managed promptly.The present study reports the unique case of a man who experienced rupture and hemorrhage of a hepatic hemangioma (HH) due to perforation of the gallbladder fundus. After en block resection of the hemangioma and gallbladder using the Pringle maneuver, the patient made an uneventful recovery without complications...
February 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28190707/safety-and-efficacy-of-percutaneous-microwave-hepatic-ablation-near-the-heart
#15
George A Carberry, Amanda R Smolock, Mircea Cristescu, Shane A Wells, Timothy J Ziemlewicz, Meghan G Lubner, J Louis Hinshaw, Christopher L Brace, Fred T Lee
PURPOSE: To evaluate safety and efficacy of percutaneous hepatic microwave (MW) ablation performed near the heart. MATERIALS AND METHODS: This study reviewed 118 consecutive peripheral (ablation zone margins within 5 mm of liver capsule) percutaneous MW hepatic ablations performed between June 2010 and August 2015. Ablation zones of 27 tumors (22.8%) extended to ≤ 5 mm from myocardium, and these ablations comprised the study group; the remaining ablations formed the control group...
February 9, 2017: Journal of Vascular and Interventional Radiology: JVIR
https://www.readbyqxmd.com/read/28186622/changes-in-echogenicity-of-hepatic-hemangiomas-during-the-valsalva-maneuver
#16
Hyung Jin Won, Pyo Nyun Kim, Jong Seok Lee
BACKGROUND: We aimed to evaluate changes in echogenicity of hepatic hemangiomas during the Valsalva maneuver. METHODS: We examined 16 liver hemangiomas in 12 patients with a mean diameter of 1.5 cm (range, 0.7-2.2 cm), which showed variations in echogenicity during the Valsalva maneuver. Two radiologists reviewed the sonographic (US) images of the hemangiomas at three different times: prior to the Valsalva maneuver, during the Valsalva maneuver, and on follow-up US examinations...
February 10, 2017: Journal of Clinical Ultrasound: JCU
https://www.readbyqxmd.com/read/28163295/shrunken-hepatic-hemangioma-following-delineated-peritumoral-hyperintensity-on-gadoxetic-acid-disodium-enhanced-mr-imaging
#17
Hiroki Haradome, Takao Okubo, Yusuke Toda, Jun Woo, Tadatoshi Takayama, Osamu Abe
No abstract text is available yet for this article.
February 6, 2017: Magnetic Resonance in Medical Sciences: MRMS
https://www.readbyqxmd.com/read/28130585/infrahepatic-inferior-vena-cava-clamping-with-pringle-maneuvers-for-laparoscopic-extracapsular-enucleation-of-giant-liver-hemangiomas
#18
Wanguang Zhang, Jian Wang, Changhai Li, Zhanguo Zhang, Najib Isse Dirie, Hanhua Dong, Shuai Xiang, Wei Zhang, Zhiwei Zhang, Bixiang Zhang, Xiaoping Chen
BACKGROUND: This study aimed to determine the feasibility of the extracapsular enucleation method for giant liver hemangiomas by infrahepatic inferior vena cava (IVC) clamping and the Pringle maneuver to control intraoperative bleeding under laparoscopic hepatectomy. METHODS: From January 2012 to January 2016, 36 patients underwent laparoscopic extracapsular enucleation of giant liver hemangiomas. Patients were divided into two groups: infrahepatic IVC clamping + Pringle maneuvers group (IVCP group, n = 15) and the Pringle maneuvers group (Pringle group, n = 21)...
January 27, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28126252/characteristics-and-operative-treatment-of-extremely-giant-liver-hemangioma-20%C3%A2-cm
#19
Xiaolei Liu, Zhiying Yang, Haidong Tan, Liguo Liu, Li Xu, Yongliang Sun, Shuang Si, Jia Huang, Wenying Zhou
BACKGROUND: Giant liver hemangioma >20 cm may cause severe complications; therefore, operative treatment can be highly difficult and risky. No studies have been performed to determine the characteristics of this subgroup. METHODS: A retrospective study was performed on 141 patients who underwent operative treatment for liver hemangioma. The patients were divided into an extremely giant hemangioma group (>20 cm, 36 cases) and a giant hemangioma group (>10 cm but <20 cm, 105 cases)...
January 23, 2017: Surgery
https://www.readbyqxmd.com/read/28109376/cardiac-cavernous-hemangioma-coexisting-with-pulmonary-cavernous-hemangiomas-and-giant-hepatic-hemangioma
#20
Chunping Wang, Hao Chen, Lin Sun, Yunqing Mei
We describe a case of cardiac cavernous hemangioma with coexisting pulmonary cavernous hemangiomas and hepatic hemangioma. A 35-year-old woman who had previously received a living donor liver transplant to cure giant hepatic hemangioma was seen because of chest pain. A cardiac neoplasm and multiple pulmonary nodules were detected. The tumor was surgically removed, and biopsy specimens were taken from the lung nodules. Histopathologic examination confirmed that both lesions were cavernous hemangiomas. The patient was discharged without adverse events postoperatively...
February 2017: Annals of Thoracic Surgery
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