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Pain and preterm infant

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https://www.readbyqxmd.com/read/29776872/oral-glucose-and-listening-to-lullaby-to-decrease-pain-in-preterm-infants-supported-with-ncpap-a-randomized-controlled-trial
#1
Kadir Şerafettin Tekgündüz, Sevinç Polat, Ayşe Gürol, Serap Ejder Apay
Preterm infants spend the early days of their lives in neonatal intensive care units, where they undergo many minor painful procedures. There are many nonpharmacologic methods that can effectively reduce the pain response of neonates who undergo routine procedures. This study aimed to investigate whether oral glucose and listening to lullabies could bring pain relief during the removal and reinsertion of the tracheal tube and also oronasopharyngeal suctioning in premature infants to whom nasal continuous positive airway pressure was applied...
May 15, 2018: Pain Management Nursing: Official Journal of the American Society of Pain Management Nurses
https://www.readbyqxmd.com/read/29712500/effects-of-fentanyl-for-pain-control-and-neuroprotection-in-very-preterm-newborns-on-mechanical-ventilation
#2
Jie Qiu, Li Zhao, Yang Yang, Jing-Han Zhang, Yun Feng, Rui Cheng
OBJECTIVE: This study aimed to evaluate the cerebral protection effect of fentanyl infusion in very preterm infants in the first 72 h of mechanical ventilation. METHODS: In this double-blind, randomized, controlled trial, mechanically ventilated newborns (< 32 weeks' gestational age) were randomized to fentanyl (continuous infusion of fentanyl) or placebo (continuous infusion of glucose, controls) in the first 72 h of the mechanical ventilation period. The premature infant pain profile (PIPP), cerebral blood flow velocity, neuron-specific enolase (NSE) concentrations in plasma samples, and cerebral function monitoring (CFM) recordings were evaluated...
April 30, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29698249/memories-of-infant-pain-in-the-neonatal-intensive-care-unit-influence-posttraumatic-stress-symptoms-in-mothers-of-infants-born-preterm
#3
Jillian Vinall, Melanie Noel, Timothy Disher, Kim Caddell, Marsha Campbell-Yeo
OBJECTIVES: The birth of a preterm infant and witnessing ones' infant in pain is remembered by parents as being one of the most stressful aspects of the neonatal care intensive unit (NICU). Elevated symptoms of posttraumatic stress symptoms (PTSS) are highly prevalent among mothers of preterm infants, however, little is known about mothers' memories of invasive procedures in the NICU and how these memories may contribute to the development of PTSS. We examined the relationships between number of invasive procedures, mothers' memories of these procedures, and their PTSS at discharge from the NICU...
April 25, 2018: Clinical Journal of Pain
https://www.readbyqxmd.com/read/29694490/bundle-of-measures-to-support-intrahospital-exclusive-breastfeeding-evidence-of-systematic-reviews
#4
Kelly Pereira Coca, Vânia Lopes Pinto, Flavia Westphal, Pâmilla Nayara Alves Mania, Ana Cristina Freitas de Vilhena Abrão
OBJECTIVE: To identify the main recommendations found in systematic reviews regarding exclusive breastfeeding protective factors. DATA SOURCE: Integrative review based on the guiding question: What evidence is found in literature regarding the protective factors of exclusive breastfeeding during the intrahospital period? A search was conducted in the Cochrane Library, PubMed/MEDLINE and LILACS database using the keyword "Breast Feeding" and the word "Breastfeeding"...
April 23, 2018: Revista Paulista de Pediatria: Orgão Oficial da Sociedade de Pediatria de São Paulo
https://www.readbyqxmd.com/read/29684832/effect-of-non-nutritive-sucking-and-sucrose-alone-and-in-combination-for-repeated-procedural-pain-in-preterm-infants-a-randomized-controlled-trial
#5
Haixia Gao, Mei Li, Honglian Gao, Guihua Xu, Fang Li, Jing Zhou, Yunsu Zou, Honghua Jiang
BACKGROUND: Sucrose combined with non-nutritive sucking provided better pain relief than sucrose or non-nutritive sucking alone in a single painful procedure. However, whether the combination of non-nutritive sucking with sucrose could obtain a significant difference in analgesic effect of the repeated procedural pain than any single intervention has not been established. OBJECTIVE: To compare the effect of non-nutritive sucking and sucrose alone and in combination of repeated procedural pain in preterm infants...
April 7, 2018: International Journal of Nursing Studies
https://www.readbyqxmd.com/read/29675875/effects-of-a-supportive-care-bundle-on-sleep-variables-of-preterm-infants-during-hospitalization
#6
Hsiang-Yun Lan, Luke Yang, Kao-Hsian Hsieh, Ti Yin, Yue-Cune Chang, Jen-Jiuan Liaw
Sleep is important for preterm infants' brain development, but they are frequently exposed to painful procedures in the neonatal intensive care unit (NICU) that disturb their sleep cycle and affect their growth. The purpose of this study was to examine the prolonged effects of a supportive care bundle (modulation of the infants' states, non-nutritive sucking, facilitated tucking, and oral sucrose feeding) on preterm infants' sleep variables (sleep efficiency, total sleep time, sleep latency, and frequency of wake bouts) during hospitalization...
April 20, 2018: Research in Nursing & Health
https://www.readbyqxmd.com/read/29628409/prospective-follow-up-of-a-cohort-of-preterm-infants-33-wg-receiving-ketamine-for-tracheal-intubation-in-the-delivery-room-neurological-outcome-at-1-and-2-years
#7
C Elalouf, A-G Le Moing, C Fontaine, A Leke, G Kongolo, J Gondry, P Tourneux
OBJECTIVE: Although ketamine analgesia is effective in reducing pain and facilitating the tracheal intubation of newborns in the delivery room, no data on the neurological effects of this treatment are available. This study compared the neurodevelopmental outcomes at 2 years of age in a cohort of preterm newborns having received ketamine prior to tracheal intubation at birth (the ketamine group) and in a control group. METHODS: We included newborns delivered at less than 33 weeks gestational age (WGA) having undergone tracheal intubation at birth...
April 5, 2018: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
https://www.readbyqxmd.com/read/29621826/cognitive-functions-of-the-fetus
#8
Aida Salihagic Kadic, Asim Kurjak
The human brain is intricately designed to execute cognitive functions, such as perception, attention, action, memory and learning. The complete nervous system is active during prenatal development and the aim of this review is to present data on fetal cognitive functions. The fetus processes sensory stimuli at a cortical level, including painful stimulus, from about 25 weeks of gestation onwards. At gestational week 34, the fetus is able not only to perceive complex acoustic external sounds but also to discriminate between different sounds...
April 2018: Ultraschall in der Medizin
https://www.readbyqxmd.com/read/29598896/effects-of-hammock-positioning-in-behavioral-status-vital-signs-and-pain-in-preterms-a-case-series-study
#9
Valdecira Rodrigues de Jesus, Pricila Mara Novais de Oliveira, Vivian Mara Gonçalves de Oliveira Azevedo
BACKGROUND: The hammock positioning within the incubators simulates the intrauterine environment, however, there is little evidence of its benefits and possible risks. OBJECTIVES: The aim of this study was to assess the effects of hammock positioning on behavioral status, vital signs, and pain in very low birth weight preterm newborns. METHODS: This is a quasi-experimental/case series study in which premature infants (<1500g) were positioned in supine for one hour in a hammock...
March 15, 2018: Brazilian Journal of Physical Therapy
https://www.readbyqxmd.com/read/29583110/vitamin-a-supplementation-by-endotracheal-application-of-a-nano-encapsulated-preparation-is-feasible-in-ventilated-preterm-lambs
#10
Holger B Wahl, Matthias C Hütten, Dominik Monz, Erol Tutdibi, Daan Ophelders, Maria Nikiforou, Thomas Tschernig, Ludwig Gortner, Donatus Nohr, Hans K Biesalski, Boris W Kramer
BACKGROUND: Vitamin A (VA) is crucial for lung growth and development. In premature infants, inadequate VA levels are associated with an increased risk of bronchopulmonary dysplasia (BPD). Intramuscular VA supplementation has been shown to decrease the incidence of BPD, but is not widely used in the clinical setting due to concerns about feasibility and pain. We studied VA kinetics, distribution, and the induction of early genetic expression of retinoid homeostatic genes in the lung after endotracheal and intravenous application in a preterm lamb model...
March 27, 2018: Journal of Aerosol Medicine and Pulmonary Drug Delivery
https://www.readbyqxmd.com/read/29579482/effect-of-recorded-maternal-voice-breast-milk-odor-and-incubator-cover-on-pain-and-comfort-during-peripheral-cannulation-in-preterm-infants
#11
Dilek Küçük Alemdar
PURPOSE: This study was conducted to assess the effect of recorded maternal voice, breast milk odor, and incubator cover on the pain and comfort of preterm infants during peripheral cannulation. METHODS: This study was a randomized controlled trial. The sample of the study included 136 preterm infants who met the case selection criteria. The infants were randomly assigned to different groups. DATA COLLECTION TOOL: In the study, a recorded maternal voice was played to the maternal voice group...
April 2018: Applied Nursing Research: ANR
https://www.readbyqxmd.com/read/29503275/feasibility-of-helmet-delivered-continous-positive-airway-pressure-in-very-low-birthweight-infants
#12
LETTER
Almudena Alonso-Ojembarrena, Antonio Segado-Arenas, Isabel Benavente-Fernández, Simón Pedro Lubián-López
We describe our experience with helmet-delivered continuous positive airway pressure in five preterm newborns. We analyzed oxygen requirement, arterial oxygen saturation, respiratory rate, medium arterial pressure, heart rate, apneic spells and patient's comfort. The patients' vital signs or pain scale were not different before and after treatment.
February 15, 2018: Indian Pediatrics
https://www.readbyqxmd.com/read/29428919/randomized-control-trial-comparing-pain-control-interventions-in-preterm-neonates
#13
Vivek V Shukla, Satvik Bansal, Archana Nimbalkar, Apurva Chapla, Ajay Phatak, Dipen Patel, Somashekhar Nimbalkar
OBJECTIVE: To compare individual efficacy and additive effects of pain control interventions in preterm neonates. DESIGN: Randomized controlled trial. SETTING: Level-3 University affiliated neonatal intensive care unit. PARTICIPANTS: 200 neonates (26-36 weeks gestational age) requiring heel-stick for bedside glucose assessment. Exclusion criteria were neurologic impairment and critical illness precluding study interventions...
February 9, 2018: Indian Pediatrics
https://www.readbyqxmd.com/read/29422195/practice-based-interpretation-of-ultrasound-studies-leads-the-way-to-more-effective-clinical-support-and-less-pharmaceutical-and-surgical-intervention-for-breastfeeding-infants
#14
REVIEW
Pamela Douglas, Donna Geddes
BACKGROUND: breastfeeding optimises health outcomes for both mothers and infants. Although most women want to breastfeed, they report commencing infant formula because of nipple pain, unsettled infant behaviour, and infant growth concerns. To date, existing approaches to fit and hold ('latch and positioning') have been demonstrated not to help breastfeeding outcomes, and women report widespread dissatisfaction with the quality of support and conflicting advice they receive. Breast and nipple pain, difficulty with latching and sucking, fussing at the breast, back-arching, marathon feeds, excessively frequent feeds, poor weight gain, breast refusal, and crying due to poor satiety often signal suboptimal positional instability and impaired milk transfer, but may be misdiagnosed as medical conditions...
March 2018: Midwifery
https://www.readbyqxmd.com/read/29396320/pain-exposure-associates-with-telomere-length-erosion-in-very-preterm-infants
#15
Livio Provenzi, Roberto Giorda, Monica Fumagalli, Uberto Pozzoli, Francesco Morandi, Giunia Scotto di Minico, Fabio Mosca, Renato Borgatti, Rosario Montirosso
Very preterm (VPT) infants (gestational age < 32 weeks) require long-lasting hospitalization in the Neonatal Intensive Care Unit (NICU), even in absence of severe morbidities. During NICU stay, life-saving interventions occur and include invasive and painful skin-breaking procedures (NICU-related stress), which constitute a major early adverse experience for VPT infants. Telomeres are repeat-sequence at the end of chromosomes, which shorten with age and are highly susceptible to life adversities: the exposure to early adverse experiences is associated with shorter telomere length (TL)...
March 2018: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/29378417/epigenetic-modifications-following-noxious-stimuli-in-infants
#16
Linda A Hatfield, Rebecca K Hoffman, Rosemary C Polomano, Yvette Conley
PURPOSE: To recruit healthy full- and preterm infants into genetic research and determine the effectiveness of a noninvasive DNA sampling technique for comparing epigenetic modifications. BACKGROUND: Noxious stimuli during a vulnerable period of infant neuronal plasticity may trigger long-term epigenetic changes affecting neurodevelopment, pain modulation, and reactivity. Recognizing epigenetic pain findings is problematic because parents are reluctant to enroll newborns into genetic research...
March 2018: Biological Research for Nursing
https://www.readbyqxmd.com/read/29369446/objective-assessment-of-induced-acute-pain-in-neonatology-with-the-newborn-infant-parasympathetic-evaluation-nipe-index
#17
C Cremillieux, A Makhlouf, V Pichot, B Trombert, H Patural
BACKGROUND: Objective tools are needed to improve pain assessment in newborns. The aim of this study was to assess the correlation between the Newborn Infant Parasympathetic Evaluation (NIPE) index and two pain scales during a painful procedure in premature infants. METHOD: Each baby born at least at 26 weeks of gestational age (GA) undergoing a planned painful procedure in the Neonatal Intensive Care Unit (NICU) was eligible. NIPE index, heart rate variability (HRV) indices and Neonatal Acute Pain scale (DAN) were recorded across three periods: the first at rest 5 min before the painful procedure (T1), the second during it (T2), and the third 3 min after the end of it (T3)...
January 25, 2018: European Journal of Pain: EJP
https://www.readbyqxmd.com/read/29345047/effects-of-maternal-heart-sounds-on-pain-and-comfort-during-aspiration-in-preterm-infants
#18
Dilek Küçük Alemdar, Fatma Güdücü Tüfekcİ
AIM: This study aimed to evaluate the effects of providing prerecorded maternal heart sounds on the level of pain and comfort that are experienced by preterm infants during aspiration. METHODS: This was a randomized controlled trial. Preterm infants (N = 62) who were receiving care or treatment at a neonatal intensive care unit were eligible for participation in this study. Infants in the intervention group (n = 32) were provided with prerecorded maternal heart sounds before, during, and after aspiration, whereas the infants in the control group (n = 30) received routine care...
January 17, 2018: Japan Journal of Nursing Science: JJNS
https://www.readbyqxmd.com/read/29341379/erector-spinae-plane-block-for-inguinal-hernia-repair-in-preterm-infants
#19
Maria A Hernandez, Lucio Palazzi, Julio Lapalma, Joseph Cravero
Neuro-axial anesthesia has been the preferred technique for inguinal hernia repair when attempting to avoid general anesthesia in neonates and preterm infants. We present a case where an erector spinae plane block was used successfully for this surgery. Hemodynamic stability, minimal anesthetic requirements, and excellent pain control were documented. This block promises to be a valuable and safe alternative for inguinal hernia repair, accompanying the path of neuroprotective anesthesia.
January 17, 2018: Paediatric Anaesthesia
https://www.readbyqxmd.com/read/29341252/painful-procedures-can-affect-postnatal-growth-and-neurodevelopment-in-preterm-infants
#20
Caterina Coviello, Marina Popple Martinez, Livia Drovandi, Corsini Iuri, Valentina Leonardi, Clara Lunardi, Carla Antonelli, Simone Pratesi, Carlo Dani
AIM: This Italian study evaluated whether painful procedures during the first four weeks of life were related to subsequent weight gain, head circumference (HC) and neurodevelopmental outcomes in preterm infants, METHODS: We evaluated the number of invasive procedures that infants born at less than 32 weeks of gestational age (GA) underwent in the Neonatal Intensive Care Unit of Careggi Hospital, Florence from January to December 2015. Weight and HC were recorded at birth, 36 weeks of PMA and six and 12 months of CA...
January 17, 2018: Acta Paediatrica
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