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https://www.readbyqxmd.com/read/28225519/a-cytokine-pattern-that-differentiates-preseroconversion-from-postseroconversion-phases-of-primary-hiv-infection
#1
Lucia Pastor, Erica Parker, Jorge Carrillo, Victor Urrea, Laura Fuente-Soro, Durval Respeito, Chenjerai Jairoce, Inacio Mandomando, Julià Blanco, Denise Naniche
BACKGROUND: During acute HIV infection, HIV actively replicates but seroconversion has not yet occurred. Primary HIV infection (PHI) is characterized by a transient nonspecific febrile illness, a massive inflammatory response, and the progressive appearance of anti-HIV-specific antibodies. In this study, we have identified patterns of inflammatory biomarkers associated with the innate immunological reaction before completion of a full humoral response. METHODS: A symptom-based screening was used to identify acute HIV infection in the Manhiça District Hospital in Mozambique...
April 1, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/28151870/are-gastric-hyperplastic-polyps-an-additional-manifestation-in-celiac-disease-results-from-a-retrospective-study
#2
Maria Pina Dore, Giovanni Mario Pes, Chiara Rocchi, Maria Francesca Loria, Sara Soro, Gabrio Bassotti
Gastric polyps are frequently reported in patients undergoing upper endoscopic procedures. In this retrospective study, the association between hyperplastic polyps and celiac disease in Northern Sardinia was estimated.Age, gender, body mass index, and medications taken in the 2 preceding months, including proton-pump inhibitors (PPIs), H2 receptor blockers (anti-H2), Helicobacter pylori status, endoscopic findings, and histology from charts of patients undergoing esophago-gastro-duodenoscopy were reviewed. Polyps were classified as hyperplastic, fundic gland, inflammatory, and adenomatous...
February 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28095577/optimizing-injections-of-poly-l-lactic-acid-the-6-step-technique
#3
Shino Bay Aguilera, Sean Branch, Luis Soro
The authors present a reproducible and effective technique utilizing poly-L-lactic acid for panfacial revolumization. The variable dilution ratios, reconstitution times, injection techniques and rates of nodule formation with poly-L-lactic acid can be intimidating to even experienced injectors. While there is no single cookie-cutter approach to facial volumization, this 6-step "Precise Sculpt" technique can be used as a template to reliably achieve optimal results while minimizing the risk of adverse events...
December 1, 2016: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/28003552/performance-of-the-new-turbine-mid-level-critical-care-ventilators
#4
Carlos Delgado, Jose E Romero, Jaume Puig, Ana Izquierdo, Carlos Ferrando, F Javier Belda, Marina Soro
BACKGROUND: During recent years, ventilators using turbines as flow-generating systems have become increasingly more relevant. This bench study was designed to compare triggering and pressurization of 7 turbine mid-level ICU ventilators. METHODS: We used a dual-chamber lung model to test 7 mid-level ICU ventilators in pressure support mode with levels of 10, 15, and 20 cm H2O with 2 PEEP levels of 5 cm H2O and the minimum level allowed by the ventilator. A ventilator was connected to the master chamber to simulate 2 different effort levels...
January 2017: Respiratory Care
https://www.readbyqxmd.com/read/27984415/a-cytokine-pattern-that-differentiates-pre-from-post-seroconversion-phases-of-primary-hiv-infection
#5
Lucia Pastor, Erica Parker, Jorge Carrillo, Victor Urrea, Laura Fuente-Soro, Durval Respeito, Chenjerai Jairoce, Inacio Mandomando, Julià Blanco, Denise Naniche
BACKGROUND: During acute HIV infection (AHI) HIV actively replicates but seroconversion has not yet occurred. Primary HIV infection (PHI) is characterized by a transient non-specific febrile illness, a massive inflammatory response and the progressive appearance of anti-HIV specific antibodies. In this study we have identified patterns of inflammatory biomarkers associated with the innate immunological reaction prior to completion of a full humoral response. METHODS: A symptom-based screening was used to identify AHI in the Manhiça District Hospital in Mozambique...
23, 2016: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/27901218/risk-factors-for-complications-in-peripheral-intravenous-catheters-in-adults-secondary-analysis-of-a-randomized-controlled-trial
#6
Derdried Athanasio Johann, Mitzy Tannia Reichembach Danski, Stela Adami Vayego, Dulce Aparecida Barbosa, Jolline Lind
Objective: analyze the risk factors linked to complications in peripheral intravenous catheters. Method: secondary data analysis of a randomized controlled trial with 169 medical and surgical patients placed in two groups, one with integrated safety catheter (n=90) and other using simple needle catheter (n=79), with three months follow-up time. Results: the risk factors that raised the odds of developing complications were: hospitalization between 10-19 days (p=0...
November 28, 2016: Revista Latino-americana de Enfermagem
https://www.readbyqxmd.com/read/27871710/microbiological-assessment-of-aerosol-generated-during-debond-of-fixed-orthodontic-appliances
#7
Michael Dawson, Valeria Soro, David Dymock, Robert Price, Helen Griffiths, Tom Dudding, Jonathan R Sandy, Anthony J Ireland
INTRODUCTION: The aims of this study were to describe bacterial load and diversity of the aerosol created during enamel cleanup after the removal of fixed orthodontic appliances and to assess the effect of a preprocedural mouth rinse. METHODS: The study involved the sampling of ambient air adjacent to the patient's mouth during adhesive removal using a slow-speed handpiece and a spiral fluted tungsten carbide bur without water irrigation. Sampling was carried out during enamel cleanup with or without a preprocedural mouth rinse of either sterile water or chlorhexidine...
November 2016: American Journal of Orthodontics and Dentofacial Orthopedics
https://www.readbyqxmd.com/read/27866745/urbanization-impact-on-sulfur-content-of-groundwater-revealed-by-the-study-of-urban-speleothem-like-deposits-case-study-in-paris-france
#8
E Pons-Branchu, M Roy-Barman, L Jean-Soro, A Guillerme, P Branchu, M Fernandez, E Dumont, E Douville, J L Michelot, A M Phillips
Speleothem-like deposits that develop underground in urban areas are an archive of the environmental impact of anthropic activities that has been little studied so far. In this paper, the sulfate content in shallow groundwater from northern Paris (France) is compared with the sulfur content in two 300-year-old urban carbonate deposits that grew in a historical underground aqueduct. The present-day waters of the aqueduct have very high sulfur and calcium contents, suggesting pollution from gypsum dissolution...
February 1, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/27820723/characterization-of-the-gastric-microbiota-in-a-pediatric-population-according-to-helicobacter-pylori-status
#9
Laura Llorca, Guillermo Pérez-Pérez, Pedro Urruzuno, Maria Josefa Martinez, Tadasu Iizumi, Zhan Gao, Jiho Sohn, Jennifer Chung, Laura Cox, Aurea Simón-Soro, Alex Mira, Teresa Alarcón
BACKGROUND: H. pylori colonizes the human stomach of approximately 50% of the world's population, and increases the risk of several gastric diseases. The goal of this study is to compare the gastric microbiota in pediatric patients with and without H. pylori colonization. METHODS: We studied 51 children that underwent gastric endoscopy due to dyspeptic symptoms (18 H. pylori-positive and 33 negative). Gastric biopsies were obtained for Rapid Urease Test, culture, histology and DNA extraction...
November 3, 2016: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/27765608/influence-of-geography-seasons-and-pedology-on-chemical-composition-and-anti-inflammatory-activities-of-essential-oils-from-lippia-multiflora-mold-leaves
#10
Lêniféré Chantal Soro, Sylvie Munier, Yves Pelissier, Lidwine Grosmaire, Rickey Yada, David Kitts, Anin Louise Ocho-Anin Atchibri, Caroline Guzman, Frédéric Boudard, Chantal Menut, Jean Charles Robinson, Patrick Poucheret
ETHNOPHARMACOLOGICAL RELEVANCE: Lippia multiflora is a plant with nutritional and pharmaco-therapeutic properties that is native to central and occidental Africa. The potential effects of plants on health are associated with their chemical composition. Therefore, the present study aimed to identify chemical variations in essential oils of Lippia multiflora as a function of geographic origin and time of annual harvest to determine optimal chemical profiles for ethno-pharmacotherapeutic applications...
December 24, 2016: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/27737690/neurally-adjusted-ventilatory-assist-in-patients-with-acute-respiratory-failure-study-protocol-for-a-randomized-controlled-trial
#11
Jesús Villar, Javier Belda, Jesús Blanco, Fernando Suarez-Sipmann, José Manuel Añón, Lina Pérez-Méndez, Carlos Ferrando, Dácil Parrilla, Raquel Montiel, Ruth Corpas, Elena González-Higueras, David Pestaña, Domingo Martínez, Lorena Fernández, Marina Soro, Miguel Angel García-Bello, Rosa Lidia Fernández, Robert M Kacmarek
BACKGROUND: Patient-ventilator asynchrony is a common problem in mechanically ventilated patients with acute respiratory failure. It is assumed that asynchronies worsen lung function and prolong the duration of mechanical ventilation (MV). Neurally Adjusted Ventilatory Assist (NAVA) is a novel approach to MV based on neural respiratory center output that is able to trigger, cycle, and regulate the ventilatory cycle. We hypothesized that the use of NAVA compared to conventional lung-protective MV will result in a reduction of the duration of MV...
October 13, 2016: Trials
https://www.readbyqxmd.com/read/27737388/effectiveness-and-safety-of-a-6-month-treatment-with-paricalcitol-in-patients-on-hemodialysis-with-secondary-hyperparathyroidism
#12
Inés Olaizola, Hena Caorsi, Laura Fajardo, Alejandro Ferreiro, Nieves Campistrus, Deyanira Dolinsky, Alicia Petraglia, Pablo Ambrosoni
Introduction: The mineral bone disorder, particularly secondary hyperparathyroidism, in chronic kidney disease (CKD) has a systemic impact affecting not only bone metabolism. Therefore its correction is important to prevent cardiovascular, inflammatory and immune diseases. Objective: To assess the effectiveness and safety of intravenous paricalcitol administered over a 6 month period for the treatment of secondary hyperparathyroidism (SHPT) in patients undergoing conventional hemodialysis, with close follow-up of treatment response...
July 2016: Jornal Brasileiro de Nefrologia: ʹorgão Oficial de Sociedades Brasileira e Latino-Americana de Nefrologia
https://www.readbyqxmd.com/read/27726307/high-prevalence-of-diabetes-specific-autoimmunity-in-first-degree-relatives-of-sardinian-patients-with-type-1-diabetes
#13
M Incani, C Serafini, C Satta, L Perra, F Scano, P Frongia, R Ricciardi, C Ripoli, M Soro, A Strazzera, S Zampetti, R Buzzetti, M G Cavallo, E Cossu, M G Baroni
BACKGROUND: The incidence of type 1 diabetes mellitus (T1DM) in Sardinia is among the highest in the world (44.8 cases/100,000 person-years). Recommendations of the Immunology of Diabetes Society advise evaluating autoantibody positivity in first-degree relatives (FDRs) of patients with T1DM, for their higher risk to develop the disease. The aim of this study was to determine the prevalence of beta-cell autoimmunity in FDRs of T1DM patients in Sardinia. METHODS: A total of 188 Sardinian families were recruited in collaboration between diabetes and pediatric units of university and district hospitals in Sardinia...
October 11, 2016: Diabetes/metabolism Research and Reviews
https://www.readbyqxmd.com/read/27656304/unusual-closed-traumatic-avulsion-of-both-flexor-tendons-in-zones-1-and-3-of-the-little-finger
#14
Marie-Aimée Päivi Soro, Thierry Christen, Sébastien Durand
Closed tendon avulsion of both flexor tendons in the same finger is an extremely rare condition. We encountered the case of a patient who presented a rupture of the flexor digitorum profundus in zone 1 and flexor digitorum superficialis in zone 3 in the little finger. This occurrence has not been reported previously. We hereby present our case, make a review of the literature of avulsion of both flexor tendons of the same finger, and propose a treatment according to the site of the ruptures.
2016: Case Reports in Orthopedics
https://www.readbyqxmd.com/read/27626667/role-of-mitochondrial-complex-iv-in-age-dependent-obesity
#15
Ines Soro-Arnaiz, Qilong Oscar Yang Li, Mar Torres-Capelli, Florinda Meléndez-Rodríguez, Sónia Veiga, Koen Veys, David Sebastian, Ainara Elorza, Daniel Tello, Pablo Hernansanz-Agustín, Sara Cogliati, Jose Maria Moreno-Navarrete, Eduardo Balsa, Esther Fuertes, Eduardo Romanos, Antonio Martínez-Ruiz, Jose Antonio Enriquez, Jose Manuel Fernandez-Real, Antonio Zorzano, Katrien De Bock, Julián Aragonés
Aging is associated with progressive white adipose tissue (WAT) enlargement initiated early in life, but the molecular mechanisms involved remain unknown. Here we show that mitochondrial complex IV (CIV) activity and assembly are already repressed in white adipocytes of middle-aged mice and involve a HIF1A-dependent decline of essential CIV components such as COX5B. At the molecular level, HIF1A binds to the Cox5b proximal promoter and represses its expression. Silencing of Cox5b decreased fatty acid oxidation and promoted intracellular lipid accumulation...
September 13, 2016: Cell Reports
https://www.readbyqxmd.com/read/27604807/spatial-mapping-and-prediction-of-plasmodium-falciparum-infection-risk-among-school-aged-children-in-c%C3%A3-te-d-ivoire
#16
Clarisse A Houngbedji, Frédérique Chammartin, Richard B Yapi, Eveline Hürlimann, Prisca B N'Dri, Kigbafori D Silué, Gotianwa Soro, Benjamin G Koudou, Serge-Brice Assi, Eliézer K N'Goran, Agathe Fantodji, Jürg Utzinger, Penelope Vounatsou, Giovanna Raso
BACKGROUND: In Côte d'Ivoire, malaria remains a major public health issue, and thus a priority to be tackled. The aim of this study was to identify spatially explicit indicators of Plasmodium falciparum infection among school-aged children and to undertake a model-based spatial prediction of P. falciparum infection risk using environmental predictors. METHODS: A cross-sectional survey was conducted, including parasitological examinations and interviews with more than 5,000 children from 93 schools across Côte d'Ivoire...
2016: Parasites & Vectors
https://www.readbyqxmd.com/read/27516790/primary-pulmonary-synovial-sarcoma-a-rare-neoplasm
#17
José Soro García, Montserrat Blanco Ramos, Eva María García Fontán, Miguel Ángel Cańizares Carretero, Ana González Pińeiro
Primary pulmonary synovial sarcoma is an extremely rare tumor with an unknown cause. The diagnosis is established after other primary lung malignancies or metastatic extrathoracic sarcoma have been excluded. We report the case of a 69-year-old man who presented with a well-defined mass in the right upper lobe on a chest X-ray. A video-assisted thoracoscopic surgery (VATS) right upper lobectomy was performed. Immunohistochemically, neoplastic cells were positive for vimentin, CD56 and Bcl-2, and focally positive for CD99, epithelial membrane antigen and cytokeratin 7 and 19...
June 2016: Kardiochirurgia i Torakochirurgia Polska, Polish Journal of Cardio-Thoracic Surgery
https://www.readbyqxmd.com/read/27467818/g6pd-deficiency-does-not-enhance-susceptibility-for-acquiring-helicobacter-pylori-infection-in-sardinian-patients
#18
Maria Pina Dore, Giuseppina Marras, Chiara Rocchi, Sara Soro, Giovanni Mario Pes
BACKGROUND: Subjects with glucose-6-phosphate dehydrogenase (G6PD) deficiency may be more susceptible to infections due to impaired leukocyte bactericidal activity. The disorder is common in the Mediterranean area. The aim of this study was to investigate whether G6PD deficiency may be a risk factor for acquiring H. pylori infection. METHODS: We performed a retrospective study. Data from clinical records of 6565 patients (2278 men and 4287 women, median age 51, range 7‒94) who underwent upper endoscopy between 2002 and 2014 were collected...
2016: PloS One
https://www.readbyqxmd.com/read/27449641/evaluating-the-efficacy-of-dexamethasone-in-the-treatment-of-patients-with-persistent-acute-respiratory-distress-syndrome-study-protocol-for-a-randomized-controlled-trial
#19
Jesús Villar, Javier Belda, José Manuel Añón, Jesús Blanco, Lina Pérez-Méndez, Carlos Ferrando, Domingo Martínez, Juan Alfonso Soler, Alfonso Ambrós, Tomás Muñoz, Rosana Rivas, Ruth Corpas, Francisco J Díaz-Dominguez, Marina Soro, Miguel Angel García-Bello, Rosa Lidia Fernández, Robert M Kacmarek
BACKGROUND: Although much has evolved in our understanding of the pathogenesis and factors affecting outcome of patients with acute respiratory distress syndrome (ARDS), still there is no specific pharmacologic treatment for ARDS. Several clinical trials have evaluated the utility of corticoids but none of them has demonstrated a definitive benefit due to small sample sizes, selection bias, patient heterogeneity, and time of initiation of treatment or duration of therapy. We postulated that adjunctive treatment of persistent ARDS with intravenous dexamethasone might change the pulmonary and systemic inflammatory response and thereby reduce morbidity, leading to a decrease in duration of mechanical ventilation and a decrease in mortality...
July 22, 2016: Trials
https://www.readbyqxmd.com/read/27229338/short-long-term-adverse-outcomes-after-arterial-embolisation-for-the-treatment-of-postpartum-haemorrhage-a-systematic-review
#20
REVIEW
Marie-Aimée Päivi Soro, Alban Denys, Maud de Rham, David Baud
OBJECTIVES: Arterial embolisation (AE) plays a major role in current practice in the management of postpartum haemorrhage (PPH) that fails to respond to conservative treatment. While its benefit is well known, long-term outcomes of AE have been poorly investigated. The objective of this review is to assess its potential complications and long-term effects on the patients' quality of life. METHODS: Using the terms "embolisation" and "postpartum haemorrhage", we searched the Cochrane Central Register of Controlled Trials, Medline and PubMed for published studies...
February 2017: European Radiology
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