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Lêniféré Chantal Soro, Sylvie Munier, Yves Pelissier, Lidwine Grosmaire, Rickey Yada, David Kitts, Anin Louise Ocho-Anin Atchibri, Caroline Guzman, Frédéric Boudard, Chantal Menut, Jean Charles Robinson, Patrick Poucheret
ETHNOPHARMACOLOGICAL RELEVANCE: Lippia multiflora is a plant with nutritional and pharmaco-therapeutic properties that is native to central and occidental Africa. The potential effects of plants on health are associated with their chemical composition. Therefore, the present study aimed to identify chemical variations in essential oils of Lippia multiflora as a function of geographic origin and time of annual harvest to determine optimal chemical profiles for ethno-pharmacotherapeutic applications...
October 17, 2016: Journal of Ethnopharmacology
Jesús Villar, Javier Belda, Jesús Blanco, Fernando Suarez-Sipmann, José Manuel Añón, Lina Pérez-Méndez, Carlos Ferrando, Dácil Parrilla, Raquel Montiel, Ruth Corpas, Elena González-Higueras, David Pestaña, Domingo Martínez, Lorena Fernández, Marina Soro, Miguel Angel García-Bello, Rosa Lidia Fernández, Robert M Kacmarek
BACKGROUND: Patient-ventilator asynchrony is a common problem in mechanically ventilated patients with acute respiratory failure. It is assumed that asynchronies worsen lung function and prolong the duration of mechanical ventilation (MV). Neurally Adjusted Ventilatory Assist (NAVA) is a novel approach to MV based on neural respiratory center output that is able to trigger, cycle, and regulate the ventilatory cycle. We hypothesized that the use of NAVA compared to conventional lung-protective MV will result in a reduction of the duration of MV...
October 13, 2016: Trials
Inés Olaizola, Hena Caorsi, Laura Fajardo, Alejandro Ferreiro, Nieves Campistrus, Deyanira Dolinsky, Alicia Petraglia, Pablo Ambrosoni
Introduction: The mineral bone disorder, particularly secondary hyperparathyroidism, in chronic kidney disease (CKD) has a systemic impact affecting not only bone metabolism. Therefore its correction is important to prevent cardiovascular, inflammatory and immune diseases. Objective: To assess the effectiveness and safety of intravenous paricalcitol administered over a 6 month period for the treatment of secondary hyperparathyroidism (SHPT) in patients undergoing conventional hemodialysis, with close follow-up of treatment response...
July 2016: Jornal Brasileiro de Nefrologia: ʹorgão Oficial de Sociedades Brasileira e Latino-Americana de Nefrologia
M Incani, C Serafini, C Satta, L Perra, F Scano, P Frongia, R Ricciardi, C Ripoli, M Soro, A Strazzera, S Zampetti, R Buzzetti, M G Cavallo, E Cossu, M G Baroni
BACKGROUND: The incidence of T1DM In Sardinia is among the highest in the world (44.8 cases/100,000 person-years). Recommendations of the Immunology of Diabetes Society (IDS) advise evaluating autoantibody positivity in first-degree relatives (FDR) of patients with T1DM, for their higher risk to develop the disease. The aim of this study is to determine the prevalence of beta-cell autoimmunity in first-degree relatives of T1DM patients in Sardinia. METHODS: 188 Sardinian families were recruited in collaboration between Diabetes and Paediatric Units of University and District Hospitals in Sardinia...
October 11, 2016: Diabetes/metabolism Research and Reviews
Marie-Aimée Päivi Soro, Thierry Christen, Sébastien Durand
Closed tendon avulsion of both flexor tendons in the same finger is an extremely rare condition. We encountered the case of a patient who presented a rupture of the flexor digitorum profundus in zone 1 and flexor digitorum superficialis in zone 3 in the little finger. This occurrence has not been reported previously. We hereby present our case, make a review of the literature of avulsion of both flexor tendons of the same finger, and propose a treatment according to the site of the ruptures.
2016: Case Reports in Orthopedics
Ines Soro-Arnaiz, Qilong Oscar Yang Li, Mar Torres-Capelli, Florinda Meléndez-Rodríguez, Sónia Veiga, Koen Veys, David Sebastian, Ainara Elorza, Daniel Tello, Pablo Hernansanz-Agustín, Sara Cogliati, Jose Maria Moreno-Navarrete, Eduardo Balsa, Esther Fuertes, Eduardo Romanos, Antonio Martínez-Ruiz, Jose Antonio Enriquez, Jose Manuel Fernandez-Real, Antonio Zorzano, Katrien De Bock, Julián Aragonés
Aging is associated with progressive white adipose tissue (WAT) enlargement initiated early in life, but the molecular mechanisms involved remain unknown. Here we show that mitochondrial complex IV (CIV) activity and assembly are already repressed in white adipocytes of middle-aged mice and involve a HIF1A-dependent decline of essential CIV components such as COX5B. At the molecular level, HIF1A binds to the Cox5b proximal promoter and represses its expression. Silencing of Cox5b decreased fatty acid oxidation and promoted intracellular lipid accumulation...
September 13, 2016: Cell Reports
Clarisse A Houngbedji, Frédérique Chammartin, Richard B Yapi, Eveline Hürlimann, Prisca B N'Dri, Kigbafori D Silué, Gotianwa Soro, Benjamin G Koudou, Serge-Brice Assi, Eliézer K N'Goran, Agathe Fantodji, Jürg Utzinger, Penelope Vounatsou, Giovanna Raso
BACKGROUND: In Côte d'Ivoire, malaria remains a major public health issue, and thus a priority to be tackled. The aim of this study was to identify spatially explicit indicators of Plasmodium falciparum infection among school-aged children and to undertake a model-based spatial prediction of P. falciparum infection risk using environmental predictors. METHODS: A cross-sectional survey was conducted, including parasitological examinations and interviews with more than 5,000 children from 93 schools across Côte d'Ivoire...
2016: Parasites & Vectors
José Soro García, Montserrat Blanco Ramos, Eva María García Fontán, Miguel Ángel Cańizares Carretero, Ana González Pińeiro
Primary pulmonary synovial sarcoma is an extremely rare tumor with an unknown cause. The diagnosis is established after other primary lung malignancies or metastatic extrathoracic sarcoma have been excluded. We report the case of a 69-year-old man who presented with a well-defined mass in the right upper lobe on a chest X-ray. A video-assisted thoracoscopic surgery (VATS) right upper lobectomy was performed. Immunohistochemically, neoplastic cells were positive for vimentin, CD56 and Bcl-2, and focally positive for CD99, epithelial membrane antigen and cytokeratin 7 and 19...
June 2016: Kardiochirurgia i Torakochirurgia Polska, Polish Journal of Cardio-Thoracic Surgery
Maria Pina Dore, Giuseppina Marras, Chiara Rocchi, Sara Soro, Giovanni Mario Pes
BACKGROUND: Subjects with glucose-6-phosphate dehydrogenase (G6PD) deficiency may be more susceptible to infections due to impaired leukocyte bactericidal activity. The disorder is common in the Mediterranean area. The aim of this study was to investigate whether G6PD deficiency may be a risk factor for acquiring H. pylori infection. METHODS: We performed a retrospective study. Data from clinical records of 6565 patients (2278 men and 4287 women, median age 51, range 7‒94) who underwent upper endoscopy between 2002 and 2014 were collected...
2016: PloS One
Jesús Villar, Javier Belda, José Manuel Añón, Jesús Blanco, Lina Pérez-Méndez, Carlos Ferrando, Domingo Martínez, Juan Alfonso Soler, Alfonso Ambrós, Tomás Muñoz, Rosana Rivas, Ruth Corpas, Francisco J Díaz-Dominguez, Marina Soro, Miguel Angel García-Bello, Rosa Lidia Fernández, Robert M Kacmarek
BACKGROUND: Although much has evolved in our understanding of the pathogenesis and factors affecting outcome of patients with acute respiratory distress syndrome (ARDS), still there is no specific pharmacologic treatment for ARDS. Several clinical trials have evaluated the utility of corticoids but none of them has demonstrated a definitive benefit due to small sample sizes, selection bias, patient heterogeneity, and time of initiation of treatment or duration of therapy. We postulated that adjunctive treatment of persistent ARDS with intravenous dexamethasone might change the pulmonary and systemic inflammatory response and thereby reduce morbidity, leading to a decrease in duration of mechanical ventilation and a decrease in mortality...
2016: Trials
Marie-Aimée Päivi Soro, Alban Denys, Maud de Rham, David Baud
OBJECTIVES: Arterial embolisation (AE) plays a major role in current practice in the management of postpartum haemorrhage (PPH) that fails to respond to conservative treatment. While its benefit is well known, long-term outcomes of AE have been poorly investigated. The objective of this review is to assess its potential complications and long-term effects on the patients' quality of life. METHODS: Using the terms "embolisation" and "postpartum haemorrhage", we searched the Cochrane Central Register of Controlled Trials, Medline and PubMed for published studies...
May 26, 2016: European Radiology
U Haag, J F Guest, M Soro
No abstract text is available yet for this article.
November 2014: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
Maria P Dore, Sara Soro, Chiara Rocchi, Maria F Loria, Stefano Bibbò, Giovanni M Pes
Clinical studies have shown that bismuth-containing quadruple therapy given twice a day for 10 to 14 days is effective and safe in the treatment of Helicobacter pylori infection in Sardinia. However, bismuth is no longer available in Italy. To report the effectiveness and tolerability of pantoprazole 20 mg, tetracycline 500 mg, and metronidazole 500 mg given b.i.d. (with the midday and evening meals) for 10 days supplemented with Lactobacillus reuteri (DSM 17938) 10(8)  cfu/tablet once a day for 20 days in patients treated in a routine daily practice setting...
April 2016: Medicine (Baltimore)
Amenan Anastasie Soro-Yao, Kouakou Brou, Georges Amani, Philippe Thonart, Koffi Marcelin Djè
Lactic acid bacteria (LAB) are the primary microorganisms used to ferment maize-, sorghum- or millet-based foods that are processed in West Africa. Fermentation contributes to desirable changes in taste, flavour, acidity, digestibility and texture in gruels (ogi, baca, dalaki), doughs (agidi, banku, komé) or steam-cooked granulated products (arraw, ciacry, dégué). Similar to other fermented cereal foods that are available in Africa, these products suffer from inconsistent quality. The use of LAB starter cultures during cereal dough fermentation is a subject of increasing interest in efforts to standardise this step and guaranty product uniformity...
December 2014: Tropical Life Sciences Research
Nuria Gonzalez Calzada, Enric Prats Soro, Lluis Mateu Gomez, Esther Giro Bulta, Ana Cordoba Izquierdo, Monica Povedano Panades, Jordi Dorca Sargatal, Eva Farrero Muñoz
OBJECTIVE: Non invasive ventilation (NIV) improves quality of life and extends survival in amyotrophic lateral sclerosis (ALS) patients. However, few data exist about the factors related to survival. We intended to assess the predictive factors that influence survival in patients after NIV initiation. METHODS: Patients who started NIV from 2000 to 2014 and were tolerant (compliance ≥ 4 hours) were included; demographic, disease related and respiratory variables at NIV initiation were analysed...
July 2016: Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
Sandra Soro Marín, Enrique Júdez Navarro, Antonio Salvador Alamillo Sanz, Ginés Sánchez Nievas
Cryoglobulins are immunoglobulins that precipitate at cold temperatures. Their presence can be related to a type of vasculitis referred to as cryoglobulinemia. This condition, especially mixed cryoglobulinemia, has been associated with viral infections like hepatitis C virus in 60%-90% of cases, but it has also been reported in relation to connective tissue diseases, usually resulting in a more severe course. We describe the case of a patient with seronegative polyarthritis who developed acute arterial ischemia in association with cryoglobulinemia, with a good response to rituximab therapy...
March 23, 2016: Reumatología Clinica
Soro Kountele Gona, Mahassadi Kouamé Alassan, Koffi Gnangoran Marcellin, Kissi Ya Henriette, Coulibaly Adama, Assohoun Toussaint, Ehua Adjoba Manuela, Seu Gagon Sylvain, Afum-Adjei Awuah Anthony, Ehua Somian Francis
Introduction. Surgical treatment of perforated peptic ulcer (PPU) is a challenge for surgeons in Africa. Aim. To determine risk factors of postoperative complications or mortality among black Ivoirian patients with PPU. Methods. All 161 patients (median age = 34 years, 90.7 male) operated on for PPU in the visceral and general surgery unit were enrolled in a retrospective cohort study. Variables were studied with Kaplan Meier and Cox proportional hazard models. Results. Among 161 patients operated on for PPU, 36 (27...
2016: Gastroenterology Research and Practice
Gerardo Andrés Obeso Carillo, Miguel Ángel Cañizares Carretero, Lidia Padín Barreiro, Jose Soro García, Luisa Blanco Tuimil
Primary hyperhidrosis is a frequent dysfunctional disorder characterized by excessive sweating in amounts greater than required for physiological needs. Surgery remains the mainstay of treatment when there is no response to medical therapies. Traditionally, thoracoscopic sympathectomy is performed routinely by means of general anesthesia with endotracheal intubation. Here we report the least invasive management for hyperhidrosis surgery, a nonintubated bilateral single port thoracoscopic sympathectomy in the context of an outpatient program...
December 2015: Annals of Translational Medicine
Daniel Gordin, Markku Saraheimo, Jaana Tuomikangas, Aino Soro-Paavonen, Carol Forsblom, Karri Paavonen, Birgit Steckel-Hamann, Francois Vandenhende, Loizos Nicolaou, Imre Pavo, Veikko Koivisto, Per-Henrik Groop
CONTEXT: Patients with type 2 diabetes (T2D) are at an increased risk of cardiovascular disease. OBJECTIVE: The objective of the study was to determine whether postprandial hyperglycemia affects arterial function in T2D. DESIGN: A single-center, open-label study of three groups of men were studied: 1) T2D patients with albuminuria (n = 22), 2) T2D patients without albuminuria (n = 24), and 3) nondiabetic controls (n = 25). Patients were randomized to a two-period crossover study schedule, ingesting breakfast, with or without insulin lispro (to induce low or high postprandial glycemia)...
March 2016: Journal of Clinical Endocrinology and Metabolism
Ole Broch, Jose Carbonell, Carlos Ferrando, Malte Metzner, Arne Carstens, Martin Albrecht, Matthias Gruenewald, Jan Höcker, Marina Soro, Markus Steinfath, Jochen Renner, Berthold Bein
BACKGROUND: Less-invasive and easy to install monitoring systems for continuous estimation of cardiac index (CI) have gained increasing interest, especially in cardiac surgery patients who often exhibit abrupt haemodynamic changes. The aim of the present study was to compare the accuracy of CI by a new semi-invasive monitoring system with transpulmonary thermodilution before and after cardiopulmonary bypass (CPB). METHODS: Sixty-five patients (41 Germany, 24 Spain) scheduled for elective coronary surgery were studied before and after CPB, respectively...
2015: BMC Anesthesiology
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