keyword
https://read.qxmd.com/read/38503413/barriers-and-facilitators-to-pressure-ulcer-prevention-behaviours-by-older-people-living-in-their-own-homes-and-their-lay-carers-a-qualitative-study
#21
JOURNAL ARTICLE
Jennifer Roddis, Judith Dyson, Marjolein Woodhouse, Anne Devrell, Karen Oakley, Fiona Cowdell
OBJECTIVE: To identify barriers and facilitators to pressure ulcer prevention behaviours in community-dwelling older people and their lay carers. DESIGN: Theoretically informed qualitative interviews with two-phase, deductive then inductive, thematic analysis. SETTING: The study was conducted in one geographical region in the UK, spanning several community National Health Service Trusts. PARTICIPANTS: Community-dwelling older patients at risk of pressure ulcer development (n=10) and their lay carers (n=10)...
March 18, 2024: BMJ Open
https://read.qxmd.com/read/38503249/the-effect-of-seven-step-educational-strategy-on-knowledge-of-diabetic-foot-ulcer-prevention-critical-thinking-and-self-efficacy-of-nursing-students-a-randomized-controlled-trial
#22
JOURNAL ARTICLE
Mehrad Nekouei, Fereshteh Javaheri Tehrani, Parvaneh Vasli, Malihe Nasiri
BACKGROUND: Diabetic foot ulcer is a significant complication of diabetes that carries a high mortality risk and is associated with substantial financial costs. Choosing a suitable educational model for nursing students as future nurses is necessary to improve knowledge and manage issues related to caring for diabetic patients. OBJECTIVES: To determine the effect of education based on the 7E learning cycle model on the knowledge of diabetic foot ulcer prevention, critical thinking, and self-efficacy in nursing students...
March 13, 2024: Nurse Education Today
https://read.qxmd.com/read/38501037/prevalence-of-lameness-in-dairy-cows-and-associated-risk-factors-at-hawassa-town-dairy-farms-ethiopia
#23
JOURNAL ARTICLE
Abebe Tesfaye Gessese, Abayineh Ayele, Mebrie Zemene Kinde, Asefa Asmare
Lameness is one of the greatest constraints on the productivity, health, and welfare of dairy cattle. A cross-sectional study was carried out from March 2021 to September 2021 in Hawassa town with the aim of assessing the prevalence and identifying the associated risk factors of lameness in dairy farms. The study was conducted on 440 animals belonging to 19 randomly selected intensive dairy farms. Data regarding lameness and its possible risk factors were collected both at animal and farm level using a questionnaire...
2024: Veterinary Medicine International
https://read.qxmd.com/read/38501018/traditional-chinese-medicine-treats-ulcerative-colitis-by-regulating-gut-microbiota-signaling-pathway-and-cytokine-future-novel-method-option-for-pharmacotherapy
#24
REVIEW
Tiancheng Wang, Xinyue Liu, Weijie Zhang, Jing Wang, Tingting Wang, Wei Yue, Lan Ming, Jun Cheng, Juan Sun
BACKGROUND: Ulcerative colitis (UC) is a chronic non-specific inflammatory disease with intestinal tract as the main site. The pathogenic of UC has not yet been clarified, and multiple mechanisms can lead to the pathogenesis of UC. Traditional Chinese medicine (TCM) offers an opportunity for UC treatment. TCM has become the preferred treatment for UC with characteristics of multiple targets, multiple pathways and high safety. This review attempted to summarize the characteristics of TCM (compound prescriptions, single Chinese herbs, and active ingredients) for UC treatment and discussed their pathogenesis based on analyzing the UC-related gut microbiota, signaling pathway and cytokine...
March 30, 2024: Heliyon
https://read.qxmd.com/read/38500429/-clinical-diagnosis-and-treatment-of-14-cases-of-scar-cancer-ulcer-wound-on-head-and-face
#25
JOURNAL ARTICLE
Xinchong Chen, Guangtao Huang
OBJECTIVE: To analyze the clinical characteristics of scar cancer ulcer wound of head and face, and to investigate its diagnosis and treatment. METHODS: The clinical data of 14 patients with head and facial scar cancer ulcer wounds who met the selection criteria and admitted between January 2021 and March 2022 were retrospectively analyzed. There were 8 males and 6 females. The age of onset ranged from 21 to 81 years with an average age of 61.6 years. The incubation period ranged from 1 month to 70 years, with a median of 4 years...
March 15, 2024: Chinese Journal of Reparative and Reconstructive Surgery
https://read.qxmd.com/read/38496839/bibliometric-analysis-of-systematic-review-and-meta-analysis-on-diabetic-foot-ulcer
#26
JOURNAL ARTICLE
Yanyan Wang, Cong Wang, Lei Zheng
Many clinical management strategies have been proposed to deal with diabetic foot ulcers. However, the occurrence and recurrence of foot ulcers remain the major problems for diabetics. This study aims to identify, visualize, and characterize the meta-analyses on diabetic foot ulcer research. Articles published online were retrieved from the Web of Science core collection database using a search query incorporating MeSH terms and topics related to diabetic foot ulcers and meta-analysis. The publications were then analyzed for basic characteristics, including publication year, countries, topics covered, references, and keywords discussed in the articles...
March 30, 2024: Heliyon
https://read.qxmd.com/read/38494661/effects-of-cluster-nursing-interventions-on-the-prevention-of-pressure-ulcers-in-intensive-care-units-patients-a-meta-analysis
#27
JOURNAL ARTICLE
Ai-Guo Zhang, Ling Li, Yuan-Li Li, Shun-Xia Sun, Min Wang, Xiao-Ling Tang
A meta-analysis was conducted to comprehensively evaluate the impact of cluster nursing interventions on the prevention of pressure ulcers (PUs) in intensive care unit (ICU) patients. Computer searches were performed in databases including Embase, Google Scholar, Cochrane Library, PubMed, Wanfang and China National Knowledge Infrastructure for randomized controlled trials (RCTs) implementing cluster nursing interventions for PUs prevention in ICU patients, with the search period covering the database inception to November 2023...
March 2024: International Wound Journal
https://read.qxmd.com/read/38494451/antimicrobial-resistance-in-ocular-infection-a-review
#28
REVIEW
Maria Cabrera-Aguas, Ngozi Chidi-Egboka, Himal Kandel, Stephanie L Watson
Antimicrobial resistance (AMR) is a global public health threat with significant impact on treatment outcomes. The World Health Organization's Global Action Plan on AMR recommended strengthening the evidence base through surveillance programs and research. Comprehensive, timely data on AMR for organisms isolated from ocular infections are needed to guide treatment decisions and inform researchers and microbiologists of emerging trends. This article aims to provide an update on the development of AMR in ocular organisms, AMR in bacterial ocular infections and on AMR stewardship programs globally...
March 17, 2024: Clinical & Experimental Ophthalmology
https://read.qxmd.com/read/38493376/national-institute-on-drug-abuse-clinical-trials-network-meeting-report-managing-patients-exposed-to-xylazine-adulterated-opioids-in-emergency-hospital-and-addiction-care-settings
#29
REVIEW
Jeanmarie Perrone, Rachel Haroz, Joseph D'Orazio, Giacomo Gianotti, Jennifer Love, Matthew Salzman, Margaret Lowenstein, Ashish Thakrar, Stephanie Klipp, Lisa Rae, Megan K Reed, Edward Sisco, Rachel Wightman, Lewis S Nelson
Used as a veterinary sedative and not approved for human use, xylazine has been increasingly linked with opioid overdose deaths in the United States. A growing number of people have been exposed to xylazine in the illicit opioid supply (especially fentanyl) or in other drugs, particularly in some areas of the Northeast. Xylazine is an α-2 adrenergic agonist that decreases sympathetic nervous system activity. When combined with fentanyl or heroin, it is purported to extend the duration of the opioid's sedative effect and to cause dependence and an associated withdrawal syndrome; however, data to support these concerns are limited...
March 15, 2024: Annals of Emergency Medicine
https://read.qxmd.com/read/38493274/low-dose-aspirin-use-does-not-increase-disease-activity-in-pregnant-patients-with-inflammatory-bowel-disease
#30
JOURNAL ARTICLE
Chelsea A DeBolt, Zoƫ S Gottlieb, Manasa G Rao, Shaelyn Johnson, Patricia Rekawek, Richa Deshpande, Rachel Meislin, Jill Berkin, Angela Bianco, Maria Teresa Mella, Marla C Dubinsky
BACKGROUND: The adverse effects of non-steroidal anti-inflammatory (NSAID) drugs on the gastrointestinal system are well recognized, but the effect of NSAID use on disease activity patients with inflammatory bowel disease (IBD) remains unresolved. Low-dose aspirin (LDA) is recommended for all pregnant patients with risk factors for developing preeclampsia, including autoimmune conditions. As recognition of risk factors for preeclampsia improves, the preventative use of LDA is likely to increase...
March 16, 2024: Digestive Diseases and Sciences
https://read.qxmd.com/read/38493047/the-frequency-of-pressure-injury-in-level-3-intensive-care-units-and-determination-of-risk-factors-a-cross-sectional-study
#31
JOURNAL ARTICLE
Refiye Akpolat, Hamide Sisman, Dudu Alptekin
AIM: This study was carried out to determine the prevalence of pressure injury and risk factors in patients hospitalized in a university hospital's level 3 intensive care unit. DESIGN: It is a descriptive, prospective, observational type study. METHOD: The sample of the study consisted of 176 patients aged 18 and over who were admitted to the intensive care units of a University Hospital for at least 24 h. Patient Information Form and Braden Risk Assessment Scale, Glasgow Coma Scale were used to collect data...
March 12, 2024: Journal of Tissue Viability
https://read.qxmd.com/read/38491463/a-novel-in-bed-body-posture-monitoring-for-decubitus-ulcer-prevention-using-body-pressure-distribution-mapping
#32
JOURNAL ARTICLE
Lindsay Stern, Geoff Fernie, Atena Roshan Fekr
BACKGROUND: Decubitus ulcers are prevalent among the aging population due to a gradual decline in their overall health, such as nutrition, mental health, and mobility, resulting in injury to the skin and tissue. The most common technique to prevent these ulcers is through frequent repositioning to redistribute body pressures. Therefore, the main goal of this study is to facilitate the timely repositioning of patients through the use of a pressure mat to identify in-bed postures in various sleep environments...
March 15, 2024: Biomedical Engineering Online
https://read.qxmd.com/read/38490058/pressure-ulcer-prevention-and-treatment-interventions-in-sub-saharan-africa-a-systematic-review
#33
JOURNAL ARTICLE
Julie Zuniga, Margaret Mungai, Lucy Chism, Livia Frost, Reha Kakkar, O'Brien Kyololo
BACKGROUND: The high burden of pressure ulcers (PUs) in Sub-Saharan Africa (SSA), coupled with the limited resources, underscores the need for preventive and context-specific treatment strategies. PURPOSE: Therefore, the purpose of this systematic review was to establish and elucidate PU prevention and treatment interventions tested in SSA. METHODS: This systematic review of the literature used, PRISMA to guide the search. FINDINGS: The review identified nine studies on PU prevention (three) and treatment (six)...
March 14, 2024: Nursing Outlook
https://read.qxmd.com/read/38489148/indole-3-acetic-acid-ameliorates-dextran-sulfate-sodium-induced-colitis-via-the-erk-signaling-pathway
#34
JOURNAL ARTICLE
Xinyan Qu, Yingying Song, Qingjun Li, Qi Xu, Yanru Li, Huimin Zhang, Xuemei Cheng, Charles R Mackay, Quanbo Wang, Wei Liu
Microbiota-derived catabolism of nutrients is closely related to ulcerative colitis (UC). The level of indole-3-acetic acid (IAA), a microbiota-dependent metabolite of tryptophan, was decreased significantly in the feces of UC patients. Thus supplementation with IAA could be a potential therapeutic method for ameliorating colitis. In this work, the protective effect of supplementation with IAA on dextran sulfate sodium (DSS)-induced colitis was evaluated, and the underlying mechanism was elucidated. The results indicated that the administration of IAA significantly relieved DSS-induced weight loss, reduced the disease activity index (DAI), restored colon length, alleviated intestinal injury, and improved the intestinal tight junction barrier...
March 15, 2024: Archives of Pharmacal Research
https://read.qxmd.com/read/38485738/chicoric-acid-alleviates-colitis-via-targeting-the-gut-microbiota-accompanied-by-maintaining-intestinal-barrier-integrity-and-inhibiting-inflammatory-responses
#35
JOURNAL ARTICLE
Yan Di, Yi Song, Kejia Xu, Qianxu Wang, Li Zhang, Qian Liu, Min Zhang, Xuebo Liu, Yutang Wang
Polyphenols have shown great potential to prevent ulcerative colitis. As a natural plant polyphenol, chicoric acid (CA) has antioxidant and anti-inflammatory properties. This study explored the intervention effects and potential mechanism of CA on dextran sodium sulfate (DSS)-induced colitis mice. The results showed that CA alleviated the symptoms of colitis and maintained the intestinal barrier integrity. CA significantly downregulated the mRNA expression levels of inflammatory factors including IL-6, IL-1β, TNF-α, IFN-γ, COX-2, and iNOS...
March 14, 2024: Journal of Agricultural and Food Chemistry
https://read.qxmd.com/read/38483734/rhododendron-poisoning-in-alpacas-vicugna-pacos-in-northern-germany
#36
JOURNAL ARTICLE
Johannes Schregel, Isabel Zdora, Ingo Gerhauser, Teresa Maria Punsmann, Sabine Aboling, Martin Ganter, Matthias Gerhard Wagener
Poisoning is often suspected to be the origin of disease in South American camelids (SACs) by owners, but only in a few cases this assumption can be confirmed. In small ruminants, rhododendron poisoning is a common emergency for livestock veterinarians. However, this condition has rarely been reported in SACs so far. This paper provides information regarding clinical findings, hematology, clinical chemistry, and treatment of four alpacas after presumed intake of rhododendron leaves including pathological findings of one of the animals...
March 14, 2024: Veterinary Research Communications
https://read.qxmd.com/read/38483398/clinical-efficacy-of-chlorhexidine-gargle-combined-with-recombinant-bovine-basic-fibroblast-growth-factor-gel-in-the-treatment-of-recurrent-oral-ulcers-and-its-effects-on-inflammatory-factors-immune-function-and-recurrence-rate
#37
RANDOMIZED CONTROLLED TRIAL
Haishan Cui, Pinghua Wang, Meiling Chen, Shanshan Lu
PURPOSE: To examine the clinical efficacy of a chlorhexidine gargle combined with recombinant bovine basic fibroblast growth factor (rb-bFGF) gel in the treatment of recurrent oral ulcers and its effects on inflammatory factors, immune function, and recurrence rate. MATERIALS AND METHODS: Ninety-six patients with recurrent oral ulcers were randomly assigned to two groups: experimental (treatment with chlorhexidine gargle plus rb-bFGF gel) and control (treatment with chlorhexidine gargle alone) (n = 48 cases)...
January 15, 2024: Oral Health & Preventive Dentistry
https://read.qxmd.com/read/38482547/impact-of-the-covid-19-pandemic-on-the-rate-of-lower-limb-amputation-in-veterans
#38
JOURNAL ARTICLE
Kierra J Falbo, Nicole R Walker, Amber L Wacek, Juan E Cave, Matthew D Sauerbrey, Amy A Gravely, Mary E Matsumoto, John M Looft
BACKGROUND: The COVID-19 pandemic led to changes in health care, including postponement of nonurgent appointments. These changes, combined with overall decreased activity levels, may have placed individuals with vascular disease at increased risk for skin ulceration and amputation. OBJECTIVE: To determine the rates of lower limb amputation in Veterans due to complications of diabetes and/or vascular disease in the year following onset of the COVID-19 pandemic (March 2020-March 2021) compared to the previous 3 years (March 2017-March 2020)...
March 14, 2024: PM & R: the Journal of Injury, Function, and Rehabilitation
https://read.qxmd.com/read/38479931/the-association-between-tea-consumption-and-non-malignant-digestive-system-diseases-a-mendelian-randomized-study
#39
RANDOMIZED CONTROLLED TRIAL
Qi Sun, Ning Gao, Jiangwei Song, Junjun Jia, Aiqiang Dong, Weiliang Xia
BACKGROUND: Tea consumption might be closely related to non-malignant digestive diseases. Nevertheless, this correlation remains inadequately comprehended. Therefore, our objective was to elucidate the essence of these connections. METHODS: This study employed a Mendelian randomization approach to investigate the impact of tea consumption on specific digestive disorders. Genetic data associated with tea consumption were obtained from the UK Biobank (UKB), encompassing 447,485 participants...
April 2024: Clinical Nutrition ESPEN
https://read.qxmd.com/read/38479430/misdiagnosis-of-cutaneous-epithelioid-angiosarcoma-as-diabetic-foot-ulcer-a-case-study
#40
JOURNAL ARTICLE
Yousef Almheirat, Lamis Elyamani, Ouissal Hormi, Nassiba Zerrouki, Nada Zizi, S Dikhaye
BACKGROUND: AS is a malignant tumor that originates from vascular endothelial cells and is known for a high rate of local recurrence and metastasis. CASE REPORT: A 48-year-old male presented with cutaneous epithelioid AS. Cutaneous AS of the foot is quite rare, especially in the absence of predisposing factors, and in this patient it was previously misdiagnosed as a DFU. CONCLUSION: Physicians should be aware of this rare presentation of cutaneous AS...
February 2024: Wounds: a Compendium of Clinical Research and Practice
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