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https://www.readbyqxmd.com/read/29923903/pressure-injury-risk-factors-in-critical-care-patients-a-descriptive-analysis
#1
Jill Cox, Sharon Roche, Virginia Murphy
BACKGROUND: Pressure injury (PI) development in the critical care population is multifactorial. Despite the application of evidence-based prevention strategies, PIs do occur and may be unavoidable in some patients. OBJECTIVES: To describe the risk factors associated with PI development in a sample of medical-surgical intensive care unit patients and determine whether these risk factors were congruent with the risk factors proposed in the work of the National Pressure Ulcer Advisory Panel on unavoidable PIs...
July 2018: Advances in Skin & Wound Care
https://www.readbyqxmd.com/read/29922724/case-report-of-ethanol-and-cyanoacrylate-embolisation-of-a-recurrent-uncontrollable-torrentially-bleeding-arteriovenous-malformation-of-the-finger
#2
Darius K L Aw, Hao-Yun Yap, Luke H T Tay, Kiang-Hiong Tay, Tze-Tec Chong
Introduction: In general, arteriovenous malformations (AVMs) are extremely rare, with an incidence of only 1 in 100,000. They are rarer still in the hands and present variably with bleeding, heaviness, a pulsatile mass, pain, ulceration, or necrosis. Report: The case of a 25 year old man with a rapidly bleeding right thumb AVM is presented. Bleeding was torrential and life threatening within a matter of seconds. He had previously undergone surgical ligation and embolisation twice at another centre, without success...
2018: EJVES Short Reports
https://www.readbyqxmd.com/read/29922560/the-utility-of-silk-elastin-hydrogel-as-a-new-material-for-wound-healing
#3
Shingo Kawabata, Norikazu Kanda, Yasushi Hirasawa, Kazuo Noda, Yoshitaka Matsuura, Shigehiko Suzuki, Katsuya Kawai
Cutaneous ulcers are treated with dressing materials and/or ointments to keep the wound in an appropriately moist environment. However, chronic cutaneous ulcers commonly have bacterial colonization that can cause local infection in such an environment. Therefore, the dressing materials and/or ointments should have antibacterial potency to treat chronic ulcers. Acute cutaneous wounds, by contrast, heal rapidly without local infection. The aim of treating acute cutaneous wounds is therefore not only wound closure but also preventing scar contracture after wound healing...
May 2018: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/29917335/assessment-and-management-of-older-people-with-venous-leg-ulcers
#4
Marie Todd
A venous leg ulcer (VLU) is defined as the loss of skin below the knee on the leg or foot in the presence of venous disease, which takes more than two weeks to heal. The prevalence of VLUs is increasing, especially in older people, which will increase the demand for nursing care. Development of a lower leg ulcer should trigger immediate assessment of risk factors for chronic venous disease followed by action to identify the cause and initiate treatment, which should prevent progression to more complex and chronic problems...
June 19, 2018: Nursing Older People
https://www.readbyqxmd.com/read/29916424/footwear-in-the-causation-and-prevention-of-foot-ulcers-in-diabetes-mellitus
#5
Ramaswamy Premkumar, Pitchaimuthu Rajan, Jeeva Rima, Joseph Richard
Background.: Inappropriate footwear may be a major cause of foot ulceration among patients with diabetic neuropathy in India. No study has specifically examined the types of footwear or its components in patients with diabetes mellitus and their role in causing foot ulcers. We analysed the role of commonly used footwear in India in inducing first foot ulcers (FFU) in people with diabetes. Methods.: Of 4800 patients with diabetes attending our centre over 1 year, 301 had FFU from different causes...
September 2017: National Medical Journal of India
https://www.readbyqxmd.com/read/29915630/once-versus-twice-daily-oral-proton-pump-inhibitor-therapy-for-prevention-of-peptic-ulcer-rebleeding-a-propensity-score-matched-analysis
#6
Fares Ayoub, Vikas Khullar, Debdeep Banerjee, Patrick Stoner, Tiffany Lambrou, Donevan R Westerveld, Wissam Hanayneh, Amir Y Kamel, David Estores
Background: After inpatient management of upper gastrointestinal bleeding (GIB) due to peptic ulcer disease (PUD), oral proton pump inhibitor (PPI) therapy is recommended at discharge to decrease rebleeding risk and improve ulcer healing. Our aim is to determine whether once-daily oral PPI dosing at hospital discharge is associated with inferior 30-day rebleeding outcomes as compared to twice-daily dosing. Methods: We retrospectively identified 233 patients admitted with signs and symptoms of upper GIB found to be due to PUD on upper endoscopy...
June 2018: Gastroenterology Research
https://www.readbyqxmd.com/read/29915396/probiotics-in-gastroenterology-how-pro-is-the-evidence-in-adults
#7
REVIEW
Ronald L Koretz
Probiotic usage has become popular with both medical practitioners and the community in general; patients commonly seek advice regarding what, if any, such preparation would be useful for their own diseases. Since such advice should be evidence-based, identified randomized clinical trials (RCTs) for a number of gastrointestinal conditions were reviewed; the data were organized by individual probiotic genera/species. Only trials in adults were considered. Most of the identified RCTs were small and low-quality, so any conclusions to be drawn will be limited at least by methodologic problems...
June 19, 2018: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/29914816/analysis-of-recurrent-ulcerations-at-a-multidisciplinary-diabetic-foot-unit-after-implementation-of-a-comprehensive-foot-care-program
#8
Sara Jiménez, José Antonio Rubio, Julia Álvarez, José Luis Lázaro-Martínez
BACKGROUND AND OBJECTIVE: The aim of this study was to assess the risk factors associated to recurrent diabetic foot ulcers after implementing a new preventive comprehensive foot care (CFC) program carried out by a podiatrist and an endocrinologist at a multidisciplinary diabetic foot unit (MDFU) and its potential impact in decreasing recurrent ulcers. MATERIAL AND METHODS: A retrospective cohort study including consecutive patients who attended the MDFU for the first time from 2008 to 2014 complaining of a diabetic foot ulcer that finally healed...
June 15, 2018: Endocrinología, Diabetes y Nutrición
https://www.readbyqxmd.com/read/29912306/prevalence-and-prevention-of-oesophageal-injury-during-atrial-fibrillation-ablation-a-systematic-review-and-meta-analysis
#9
Francis J Ha, Hui-Chen Han, Prashanthan Sanders, Andrew W Teh, David O'Donnell, Omar Farouque, Han S Lim
Aims: Atrio-oesophageal fistula (AOF) is a potentially lethal complication of atrial fibrillation (AF) ablation. Many studies have evaluated the presence and prevention of endoscopically-detected oesophageal lesions (EDOL) as a proxy measure for risk of AOF. This systematic review and meta-analysis sought to determine the prevalence of EDOL and effectiveness of general preventive measures during AF ablation. Methods and results: We searched electronic databases for studies reporting prevalence or prevention of EDOL post-AF ablation...
June 14, 2018: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29910628/autoamputation-of-diabetic-toe-with-dry-gangrene-a-myth-or-a-fact
#10
REVIEW
Abdullah Al Wahbi
Diabetes is associated with various complications and reduced quality of life. Of the many complications, some are life-threatening. Among these, foot complications remain an important concern. The major foot complications include foot ulceration, cellulitis, abscess, wet gangrene, dry gangrene, and necrotizing fasciitis, with different pathophysiological concepts behind each of them. Gangrene occurs due to reduced blood supply in the body tissues that leads to necrosis. This condition may arise because of an injury, infection, or other health conditions, majorly diabetes...
2018: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy
https://www.readbyqxmd.com/read/29909087/critical-appraisal-of-the-quality-of-evidence-addressing-the-diagnosis-prognosis-and-management-of-peripheral-artery-disease-in-patients-with-diabetic-foot-ulceration
#11
Stephen R Ali, Baris A Ozdemir, Robert J Hinchliffe
AIMS: There is a paucity of robust evidence on prevention and management of diabetic foot ulcers (DFUs) to inform treatment. This study appraises the current quality of the evidence addressing diagnosis, prognosis, and management of peripheral artery disease (PAD) in patients with DFUs using a newly devised 21 point scoring (TOPS) disease specific research appraisal tool published by the International Working Group on the Diabetic Foot (IWGDF) and European Wound Management Association...
June 13, 2018: European Journal of Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/29907132/association-between-multiple-comorbidities-and-self-rated-health-status-in-middle-aged-and-elderly-chinese-the-china-kadoorie-biobank-study
#12
Xingyue Song, Jing Wu, Canqing Yu, Wenhong Dong, Jun Lv, Yu Guo, Zheng Bian, Ling Yang, Yiping Chen, Zhengming Chen, An Pan, Liming Li
BACKGROUND: Understanding the correlates of self-rated health (SRH) can help public health professionals prioritize health-promotion and disease-prevention interventions. This study aimed to investigate the association between multiple comorbidities and global SRH and age-comparative SRH. METHODS: A total of 512,891 participants aged 30-79 years old were recruited into the China Kadoorie Biobank study from ten regions between 2004 and 2008. Multivariate logistic regression models were used to estimate the odds ratios (ORs) for the associations between comorbidities (including diabetes, hypertension, coronary heart disease, rheumatic heart disease, stroke, tuberculosis, emphysema/bronchitis, asthma, cirrhosis/chronic hepatitis, peptic ulcer, gallbladder disease, kidney disease, fracture, rheumatic arthritis, psychiatric disorders, depressive symptoms, neurasthenia, head injury and cancer) and SRH...
June 15, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29904348/berberine-regulates-treg-th17-balance-to-treat-ulcerative-colitis-through-modulating-the-gut-microbiota-in-the-colon
#13
Huantian Cui, Yuzi Cai, Li Wang, Beitian Jia, Junchen Li, Shuwu Zhao, Xiaoqian Chu, Jin Lin, Xiaoyu Zhang, Yuhong Bian, Pengwei Zhuang
Berberine (BBR), an alkaloid isolated from Rhizoma Coptidis, Cortex Phellode , and Berberis , has been widely used in the treatment of ulcerative colitis (UC). However, the mechanism of BBR on UC is unknown. In this study, we investigated the activities of T regulatory cell (Treg) and T helper 17 cell (Th17) in a dextran sulfate sodium (DSS)-induced UC mouse model after BBR administration. We also investigated the changes of gut microbiota composition using 16S rRNA analysis. We also examined whether BBR could regulate the Treg/Th17 balance by modifying gut microbiota...
2018: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/29902912/-6-gingerol-modulates-spermatotoxicity-associated-with-ulcerative-colitis-and-benzo-a-pyrene-exposure-in-balb-c-mice
#14
Babajide O Ajayi, Isaac A Adedara, Olumide S Ajani, Matthew O Oyeyemi, Ebenezer O Farombi
BACKGROUND: The deterioration of male reproductive health may represent an outcome of an active disease and environmental factors. The present study investigated the modulatory role of [6]-gingerol in spermatotoxicity resulting from colitis and benzo[a]pyrene (B[a]P), an environmental and food-borne pollutant. METHODS: Group I (control) mice received corn oil alone, while group II ([6]-gingerol alone) mice orally received [6]-gingerol alone at 100 mg/kg body weight...
June 27, 2018: Journal of Basic and Clinical Physiology and Pharmacology
https://www.readbyqxmd.com/read/29899291/amelioration-of-ethanol-induced-gastric-ulcers-in-rats-pretreated-with-phycobiliproteins-of-arthrospira-spirulina-maxima
#15
Oscar Guzmán-Gómez, Rosa Virginia García-Rodríguez, Lucía Quevedo-Corona, Ricardo Pérez-Pastén-Borja, Nora Lilia Rivero-Ramírez, Emmanuel Ríos-Castro, Salud Pérez-Gutiérrez, Julia Pérez-Ramos, Germán Alberto Chamorro-Cevallos
Phycobiliproteins of Arthrospira ( Spirulina ) maxima have attracted attention because of their potential therapeutic antioxidant properties. The aim of this study was to assess the possible antiulcerogenic activity of these phycobiliproteins (ExPhy) against ethanol-induced gastric ulcers in rats. To explore the possible mechanisms of action, we examined antioxidant defense enzymes (e.g., catalase, superoxide dismutase, and glutathione peroxidase), as well as the level of lipid peroxidation (MDA) and the histopathological changes in the gastric mucosa...
June 13, 2018: Nutrients
https://www.readbyqxmd.com/read/29898350/use-of-hydrocolloid-dressings-in-preventing-pressure-ulcers-in-high-risk-patients-a-retrospective-cohort
#16
Olga Lucía Cortés, Luz Dary Salazar-Beltrán, Yudi Andrea Rojas-Castañeda, Andrea Alvarado-Muriel, Aracelly Serna-Restrepo, Doris Grinspun
OBJECTIVES: This work sought to evaluate the association between using preventive hydrocolloid dressings and the onset of pressure ulcers in hospitalized patients. METHODS: Retrospective cohort study that included adult patients with high risk of pressure ulcers (PU) evaluated according to the Braden scale and who had been admitted with preventive purposes to a skin care program. The preventive care prescribed by the nursing staff included using hydrocolloid dressing plus conventional care (HD+CC) or only conventional care (CC), in a tier IV hospital in Bogotá, Colombia...
February 2018: Investigación y Educación en Enfermería
https://www.readbyqxmd.com/read/29897487/dietary-red-raspberry-reduces-colorectal-inflammation-and-carcinogenic-risk-in-mice-with-dextran-sulfate-sodium-induced-colitis
#17
Shima Bibi, Min Du, Mei-Jun Zhu
Background: Ulcerative colitis causes recurring intestinal mucosal injury and sustained inflammation, increasing the likelihood of colorectal cancer (CRC) development. Dietary red raspberry (RB) is a rich source of phytonutrients known to have anti-inflammatory activity; however, the role of RB on CRC prevention in chronic colitis has not been examined. Objective: This study examined the effects of dietary RB supplementation on inflammation, epithelium repair, and oncogenic signaling in dextran sulfate sodium (DSS)-induced chronic colitis in mice...
April 20, 2018: Journal of Nutrition
https://www.readbyqxmd.com/read/29897161/pressure-ulcers-incidence-preventive-measures-and-risk-factors-in-neonatal-intensive-care-and-intermediate-care-units
#18
Pablo García-Molina, Evelin Balaguer-López, Francisco Pedro García-Fernández, María de Los Ángeles Ferrera-Fernández, José María Blasco, José Verdú
Epidemiological studies on pressure ulcers (PUs) in hospitalised infants are scarce. Spain lacks comprehensive research studies providing data on the prevalence or incidence in this population. This work was developed to determine the incidence of PUs in hospitalised infants admitted to intensive and intermediate care units, along with relevant risk factors and preventive measures. A prospective study appraising the incidence of PUs in infants was performed. The risk factors and preventive measures were evaluated using a multivariate logistic regression model...
June 13, 2018: International Wound Journal
https://www.readbyqxmd.com/read/29895113/-how-to-improve-the-prevention-and-treatment-of-ocular-chemical-burns-in-china-important-elements
#19
Y F Huang, L L Wang
Ocular chemical burns are common and serious ocular emergencies which require immediate and intensive evaluation and treatment. Loss of vision and disfigurement affect the victims, bringing great sufferings to themselves and their families. China is the biggest developing country in the world with a large number of such cases. The prevention of ocular chemical burns is emphasized in different aspects. After emergency treatment, proper care of chemical burns is started by control of inflammation with corticosteroids...
June 11, 2018: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/29889865/hiv-infection-in-patients-with-sexually-transmitted-infections-in-zimbabwe-results-from-the-zimbabwe-sti-etiology-study
#20
Peter H Kilmarx, Elizabeth Gonese, David A Lewis, Z Mike Chirenje, Beth A Tippett Barr, Ahmed S Latif, Lovemore Gwanzura, H Hunter Handsfield, Anna Machiha, Owen Mugurungi, Cornelius A Rietmeijer
BACKGROUND: HIV and other sexually transmitted infections (STI) frequently co-occur. We conducted HIV diagnostic testing in an assessment of the etiologies of major STI syndromes in Zimbabwe. METHODS: A total of 600 patients were enrolled at six geographically diverse, high-volume STI clinics in Zimbabwe in 2014-15: 200 men with urethral discharge, 200 women with vaginal discharge, and 100 men and 100 women each with genital ulcer disease (GUD). Patients completed a questionnaire, underwent a genital examination, and had specimens taken for etiologic testing...
2018: PloS One
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