Read by QxMD icon Read

ebus AND breast cancer

P Serra, J Sanz-Santos, E Castellà, B Cirauqui, F Andreo, M Llatjós, M Avila, M Margelí, L Serrano, C Centeno, V Quiroga, M Torky, J Ruiz-Manzano
BACKGROUND: In breast cancer patients, the expression statuses of oestrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2) are crucial in the choice of treatment. Receptor expression in metastatic lesions can differ from the primary tumour. The aim of our study was to analyse the utility of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) to obtain samples allowing the identification of ER, PR and HER2 expression in patients with mediastinal metastases of breast cancer...
February 2018: Cytopathology: Official Journal of the British Society for Clinical Cytology
Filiz Oezkan, Amir Maqbul Khan, Thomas Hager, Lutz Freitag, Daniel Christoph, Kaid Darwiche
BACKGROUND: Lung cancer is the major cause of cancer death worldwide. Mediastinal lymph node staging is important for pretreatment lung cancer management. Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a well established method for mediastinal lymph node staging. Although EBUS-TBNA samples are much smaller than surgical lymph node biopsies, histopathological evaluation and molecular testing can successfully be performed. One step nucleic acid amplification (OSNA), which measures cytokeratin 19 (CK19) mRNA concentration, is a target marker that is gaining importance in quick detection of lymph node metastases in breast cancer and other cancers...
May 2016: Clinical Lung Cancer
Helmy Haja Mydin, David Miller, Mahendran Chetty, Graeme P Currie
A 67 years old female with previous breast cancer and a 40-pack year smoking history presented with recurrent lower respiratory tract infections on a background of chronic obstructive pulmonary disease. Despite a normal chest X-ray, the history of recurrent infections led to a high resolution computed tomography scan to exclude structural lung disease. This showed subcarinal lymphadenopathy, multiple nodules in the right lung and suggestion of lymphangitis. She proceeded to have EBUS-TBNA of the enlarged paratracheal and subcarinal lymph nodes...
2012: Respiratory Medicine Case Reports
H Erhan Dincer, Rafael S Andrade
Diagnostic approach to a pulmonary nodule depends upon the characteristics of the nodule and its location. Despite utilizing advanced minimally invasive diagnostic techniques, the work-up might be challenging. We report the case of a 60-year-old woman with history of breast cancer that was treated with lumpectomy 11 years earlier. She presented with a pulmonary nodule located medially in the fissure between the left upper and lower lobes. Linear EBUS was chosen as a diagnostic approach and the diagnosis of metastatic breast cancer was made without any complications...
July 2013: Journal of Bronchology & Interventional Pulmonology
Leslie Jette, Scott Parrish, Steven Cordero
SESSION TYPE: Miscellaneous Case Report Posters IPRESENTED ON: Tuesday, October 23, 2012 at 01:30 PM - 02:30 PMINTRODUCTION: An intrathoracic goiter is an uncommon phenomenon with presentations ranging from asymptomatic to complete respiratory failure. The incidence of true primary intrathoracic thyroid is even less common, and we present a case of asymptomatic primary intrathoracic goiter two years after total thryoidectomy.CASE PRESENTATION: Our patient is a 68 year old woman with an initial presentation of viral syndrome with incidental notation of heterogeneous thoracic inlet mass on CT scan...
October 1, 2012: Chest
Thitiwat Sriprasart, Catalin Nicola, Eyad Almasri
SESSION TYPE: Cancer Case Report Posters IPRESENTED ON: Tuesday, October 23, 2012 at 01:30 PM - 02:30 PMINTRODUCTION: Pulmonary embolism (PE) is the most common cause of filling defects of the pulmonary arteries as detected by CT angiography of the chest. We present here two cases of an unusual patho-etiology of pulmonary artery filling defects.CASE PRESENTATION: Case 1. A 63 year-old-male was evaluated for progressive dyspnea on exertion. He had a 20 pound weight loss. Auscultation was unremarkable. The initial chest X-ray showed an enlarged right hilum...
October 1, 2012: Chest
Dmitriy Kogan, Kelly Newton, Eldrige Pineda, Ameldia Evans, Huimin Guo, Norio Azumi, Philip Cohen, Cristina Reichner, Eric Anderson
SESSION TYPE: Miscellaneous Cases IIIPRESENTED ON: Wednesday, October 24, 2012 at 11:15 AM - 12:30 PMINTRODUCTION: Trastuzumab is an IgG1 humanized monoclonal antibody which targets Human Epidermal Growth Factor Receptor 2 (HER2). Since its development in 1998, Trastuzumab has been used for treatment of HER2 positive breast cancer. Pulmonary complications associated with Trastuzumab include acute lung injury, acute pneumonitis, organizing pneumonia, infusion-related reaction, and bronchospasm. We report a case of pulmonary sarcoidosis that developed after Trastuzumab therapy...
October 1, 2012: Chest
Takuo Shimmyo, Koji Ando, Atsushi Mochizuki, Noriaki Kurimoto, Haruhiko Nakamura
An 86-year-old woman with a history of right breast cancer resected seven years ago had a small pulmonary nodule located in left S5. Diagnosis was made by bronchoscopy using the endobronchial ultrasonography-guided sheath (EBUS-GS) method, but a histological diagnosis was not obtained. Wedge resection was performed due to suspicion of a metastatic lesion from breast cancer based on radiological findings. The tumor was subsequently found to be malignant melanoma of the lung. An initial diagnosis of primary melanoma of the lung was made because a melanoma lesion at another site was not seen despite a detailed work up...
2014: Annals of Thoracic and Cardiovascular Surgery
H Erhan Dincer
As an evolving technique, linear endobronchial ultrasound is becoming the first choice and standard of care not only to diagnose the malignant and benign mediastinal lesions but also to stage non-small cell lung cancer. Lung cancer is the leading cause of cancer-related mortality in both men and women. The disease causes more death compared with colorectal, breast, and prostate cancers combined in the United States. Staging of lung cancer determines the prognosis. The type of lung cancer has changed in the past few decades...
January 2013: Journal of Bronchology & Interventional Pulmonology
Jose Sanz-Santos, Beatriz Cirauqui, Estefania Sanchez, Felipe Andreo, Pere Serra, Eduard Monso, Eva Castellà, Mariona Llatjós, Miguel Mesa, Juan Ruiz-Manzano, Rafael Rosell
Intrathoracic lymph node enlargement is a common finding in patients with extrathoracic malignancies. Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a technique that is commonly used for lung cancer diagnosis and staging but that has not been widely investigated for the diagnosis of enlarged mediastinal and lobar lymph nodes in patients with extrathoracic malignancies. We conducted a retrospective study of 117 patients with extrathoracic malignancies who underwent EBUS-TBNA for diagnosis of intrathoracic lymph node enlargement from October 2005 to December 2009 and compared the EBUS-TBNA findings with the final diagnoses...
April 2013: Clinical & Experimental Metastasis
S Butt, R Alzebdeh, T D Kable, A O Soubani
BACKGROUND: The association between cancer and non-caseating granulomas is controversial. The aim of this study is to describe the clinical characteristics and outcome of a cohort of patients found to have non-caseating granulomas following the diagnosis of cancer. METHODS: Retrospective review of medical records. RESULTS: There were 30 patients with non-caseating granulomas following the diagnosis of cancer. There were 21 females and 14 patients were African Americans...
July 2011: Sarcoidosis, Vasculitis, and Diffuse Lung Diseases: Official Journal of WASOG
Marcus P Kennedy, Carlos A Jimenez, Ashwini D Mhatre, Rodolfo C Morice, Georgie A Eapen
BACKGROUND: Granulomatous inflammation has been previously reported in association with cancer. Endobronchial ultrasound guided transbronchial needle aspiration (EBUS-TBNA) is a new minimally invasive test for investigating mediastinal lymphadenopathy. The identification of granulomatous inflammation by EBUS-TBNA and the clinical implications of such detection in a series of patients with previously treated cancer and new mediastinal lymphadenopathy has not previously been performed. METHODS: All 153 consecutive patients undergoing EBUS-TBNA in an academic cancer institution for suspected cancer in the mediastinum (mediastinal lymphadenopathy by CT imaging) were reviewed...
February 25, 2008: Journal of Cardiothoracic Surgery
R W Stam, M M van den Heuvel-Eibrink, M L den Boer, M E G Ebus, G E Janka-Schaub, J D Allen, R Pieters
Infants with acute lymphoblastic leukemia (ALL) are more resistant to chemotherapeutic drugs than older children with ALL, except for Ara-C. Drug resistance mechanisms in infant ALL, however, remain unknown. Possibly, multidrug resistance (MDR) proteins like P-glycoprotein, MDR-associated protein (MRP1), lung resistance-related protein (LRP/MVP) and the breast cancer resistance protein (BCRP) play a role. Accordingly, we measured the mRNA levels of these proteins in infants (n=13) and non-infants (n=13) with ALL, using quantitative RT-PCR...
January 2004: Leukemia: Official Journal of the Leukemia Society of America, Leukemia Research Fund, U.K
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"