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https://www.readbyqxmd.com/read/28934403/improving-inpatient-medication-adherence-using-attendant-education-in-a-tertiary-care-hospital-in-uganda
#1
Patricia Alupo, Richard Ssekitoleko, Tracy Rabin, Robert Kalyesubula, Ivan Kimuli, Benjamin E Bodnar
Quality problem: Although widely utilized in resource-rich health care systems, the use of quality improvement (QI) techniques is less common in resource-limited environments. Uganda is a resource-limited country in Sub-Saharan Africa that faces many challenges with health care delivery. These challenges include understaffing, inconsistent drug availability and inefficient systems that limit the provision of clinical care. Initial assessment: Poor adherence to prescribed inpatient medications was identified as a key shortcoming of clinical care on the internal medicine wards of Mulago National Referral Hospital, Kampala, Uganda...
August 1, 2017: International Journal for Quality in Health Care
https://www.readbyqxmd.com/read/28933850/an-efficient-strategy-for-the-calculation-of-solvation-free-energies-in-water-and-chloroform-at-the-quantum-mechanical-molecular-mechanical-level
#2
Meiting Wang, Pengfei Li, Xiangyu Jia, Wei Liu, Yihan Shao, Wenxin Hu, Jun Zheng, Bernard R Brooks, Ye Mei
The partitioning of solute molecules between immiscible solvents with significantly different polarities is of great importance. The polarization between the solute and solvent molecules plays an essential role in determining the solubility of the solute, which makes computational studies utilizing molecular mechanics (MM) rather difficult. In contrast, quantum mechanics (QM) can provide more reliable predictions. In this work, the partition coefficients of the side chain analogs of some amino acids between water and chloroform were computed...
September 21, 2017: Journal of Chemical Information and Modeling
https://www.readbyqxmd.com/read/28933708/statewide-longitudinal-progression-of-the-whole-patient-measure-of-safety-in-south-carolina
#3
Christine B Turley, Jordan Brittingham, Aunyika Moonan, Dianne Davis, Hrishikesh Chakraborty
Meaningful improvement in patient safety encompasses a vast number of quality metrics, but a single measure to represent the overall level of safety is challenging to produce. Recently, Perla et al. established the Whole-Person Measure of Safety (WPMoS) to reflect the concept of global risk assessment at the patient level. We evaluated the WPMoS across an entire state to understand the impact of urban/rural setting, academic status, and hospital size on patient safety outcomes. The population included all South Carolina (SC) inpatient discharges from January 1, 2008, through to December 31, 2013, and was evaluated using established definitions of highly undesirable events (HUEs)...
September 4, 2017: Journal for Healthcare Quality: Official Publication of the National Association for Healthcare Quality
https://www.readbyqxmd.com/read/28930872/improving-vertical-jump-profiles-through-prescribed-movement-plans
#4
John K Mayberry, Bryce Patterson, Phil Wagner
Developing practical, reliable, and valid methods for monitoring athlete wellness and injury risk is an important goal for trainers, athletes, and coaches. Previous studies have shown that the countermovement vertical jump test (CMJ) is both a reliable and valid metric for evaluating an athlete's condition. This study examines the effectiveness of prescribed workouts on improving quality of movement during CMJ. The dataset consists of 2425 pairs of CMJ scans for high school, college, and professional athletes training at a privately owned facility...
September 11, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28929392/preventing-early-bouncebacks-to-the-neurointensive-care-unit-a-retrospective-analysis-and-quality-improvement-pilot
#5
David G Coughlin, Monisha A Kumar, Neha N Patel, Rebecca L Hoffman, Scott E Kasner
BACKGROUND: Early unplanned readmissions of "bouncebacks" to intensive care units are a healthcare quality metric and result in higher mortality and greater cost. Few studies have examined bouncebacks to the neurointensive care unit (neuro-ICU), and we sought to design and implement a quality improvement pilot to reduce that rate. METHODS: First, we performed a retrospective chart review of 504 transfers to identify potential bounceback risk factors. Risk factors were assessed on the day of transfer by the transferring physician identifying patients as "high risk" or "low risk" for bounceback...
September 19, 2017: Neurocritical Care
https://www.readbyqxmd.com/read/28929169/validation-of-pruritus-measures-gathered-with-the-electronic-patient-reported-outcome-system-mopat
#6
Michael Storck, Claudia Zeidler, Mirjam Rehr, Claudia Riepe, Martin Dugas, Sonja Stà Nder, Iã Aki Soto-Rey
In order to improve diagnosis and treatment, physicians require information about the social context and quality of life of their patients. The Center for Chronic Pruritus at the University Hospital Münster achieves this goal using the electronic patient-reported outcome system “Mobile Patient Survey”, which assesses pruritus and quality of life measures. The aim of this study is to evaluate the consistency and reliability of such measures. A total of 42 patients, age range 19â€"82 years, participated in the study and were asked to assess the measures at baseline via a paper questionnaire, and to use the “Mobile Patient Survey” at baseline and after 1 h in order to test reliability...
September 20, 2017: Acta Dermato-venereologica
https://www.readbyqxmd.com/read/28926813/risk-assessment-to-groundwater-of-pit-latrine-rural-sanitation-policy-in-developing-country-settings
#7
Jan O Back, Michael O Rivett, Laura B Hinz, Nyree Mackay, Gift J Wanangwa, Owen L Phiri, Chrispine Emmanuel Songola, Mavuto A S Thomas, Steve Kumwenda, Muthi Nhlema, Alexandra V M Miller, Robert M Kalin
Parallel global rise in pit-latrine sanitation and groundwater-supply provision is of concern due to the frequent spatial proximity of these activities. Study of such an area in Malawi has allowed understanding of risks posed to groundwater from the recent implementation of a typical developing-country pit-latrine sanitation policy to be gained. This has assisted the development of a risk-assessment framework approach pragmatic to regulatory-practitioner management of this issue. The framework involves water-supply and pit-latrine mapping, monitoring of key groundwater contamination indicators and surveys of possible environmental site-condition factors and culminates in an integrated statistical evaluation of these datasets to identify the significant factors controlling risks posed...
September 16, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28925747/protocol-and-quality-assurance-for-carotid-imaging-in-100-000-participants-of-uk-biobank-development-and-assessment
#8
Sean Coffey, Adam J Lewandowski, Steve Garratt, Rudy Meijer, Steven Lynum, Ram Bedi, James Paterson, Mohammad Yaqub, J Alison Noble, Stefan Neubauer, Steffen E Petersen, Naomi Allen, Cathie Sudlow, Rory Collins, Paul M Matthews, Paul Leeson
Background Ultrasound imaging is able to quantify carotid arterial wall structure for the assessment of cerebral and cardiovascular disease risks. We describe a protocol and quality assurance process to enable carotid imaging at large scale that has been developed for the UK Biobank Imaging Enhancement Study of 100,000 individuals. Design An imaging protocol was developed to allow measurement of carotid intima-media thickness from the far wall of both common carotid arteries. Six quality assurance criteria were defined and a web-based interface (Intelligent Ultrasound) was developed to facilitate rapid assessment of images against each criterion...
January 1, 2017: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/28925582/the-dangers-of-oversimplification-quality-metrics-and-lung-transplantation
#9
EDITORIAL
Victor van Berkel
While many aspects of medical care are learning how to cope with the sudden proliferation of publicly reported quality metrics[1], the transplant community has been interpreting this type of data for over thirty years. Under the National Organ Transplantation Act of 1984, transplant centers are required to report their candidate and recipient information to the Organ Procurement and Transplantation Network (OPTN), and that data is then analyzed by the Scientific Registry of Transplant Recipients (SRTR), with outcomes reported on a twice yearly basis on a public website (www...
September 19, 2017: American Journal of Transplantation
https://www.readbyqxmd.com/read/28925419/mosaicqa-a-general-approach-to-facilitate-basic-data-quality-assurance-for-epidemiological-research
#10
Martin Bialke, Henriette Rau, Thea Schwaneberg, Rene Walk, Thomas Bahls, Wolfgang Hoffmann
BACKGROUND: Epidemiological studies are based on a considerable amount of personal, medical and socio-economic data. To answer research questions with reliable results, epidemiological research projects face the challenge of providing high quality data. Consequently, gathered data has to be reviewed continuously during the data collection period. OBJECTIVES: This article describes the development of the mosaicQA-library for non-statistical experts consisting of a set of reusable R functions to provide support for a basic data quality assurance for a wide range of application scenarios in epidemiological research...
May 29, 2017: Methods of Information in Medicine
https://www.readbyqxmd.com/read/28924979/quantification-of-etoposide-hypersensitivity-a-sensitive-functional-method-for-assessing-pluripotent-stem-cell-quality
#11
Frank J Secreto, Xing Li, Alyson J Smith, Elizabeth S Bruinsma, Ester Perales-Clemente, Saji Oommen, Gresin Hawse, Sybil C L Hrstka, Bonnie K Arendt, Emma B Brandt, Dennis A Wigle, Timothy J Nelson
Human induced pluripotent stem cells (hiPSC) hold great promise in diagnostic and therapeutic applications. However, translation of hiPSC technology depends upon a means of assessing hiPSC quality that is quantitative, high-throughput, and can decipher malignant teratocarcinoma clones from normal cell lines. These attributes are lacking in current approaches such as detection of cell surface makers, RNA profiling, and/or teratoma formation assays. The latter remains the gold standard for assessing clone quality in hiPSCs, but is expensive, time-consuming, and incompatible with high-throughput platforms...
September 19, 2017: Stem Cells Translational Medicine
https://www.readbyqxmd.com/read/28924574/structural-similarity-index-family-for-image-quality-assessment-in-radiological-images
#12
Gabriel Prieto Renieblas, Agustín Turrero Nogués, Alberto Muñoz González, Nieves Gómez-Leon, Eduardo Guibelalde Del Castillo
The structural similarity index (SSIM) family is a set of metrics that has demonstrated good agreement with human observers in tasks using reference images. These metrics analyze the viewing distance, edge information between the reference and the test images, changed and preserved edges, textures, and structural similarity of the images. Eight metrics based on that family are proposed. This new set of metrics, together with another eight well-known SSIM family metrics, was tested to predict human performance in some specific tasks closely related to the evaluation of radiological medical images...
July 2017: Journal of Medical Imaging
https://www.readbyqxmd.com/read/28921580/integrating-prior-information-into-microwave-tomography-part-1-impact-of-detail-on-image-quality
#13
Douglas Kurrant, Anastasia Baran, Joe LoVetri, Elise Fear
PURPOSE: The authors investigate the impact that incremental increases in the level of detail of patient-specific prior information have on image quality and the convergence behavior of an inversion algorithm in the context of near-field microwave breast imaging. A methodology is presented that uses image quality measures to characterize the ability of the algorithm to reconstruct both internal structures and lesions embedded in fibroglandular tissue. The approach permits key aspects that impact the quality of reconstruction of these structures to be identified and quantified...
September 17, 2017: Medical Physics
https://www.readbyqxmd.com/read/28921446/can-a-novel-icu-data-display-positively-affect-patient-outcomes-and-save-lives
#14
Natalia Olchanski, Mikhail A Dziadzko, Ing C Tiong, Craig E Daniels, Steve G Peters, John C O'Horo, Michelle N Gong
The aim of this study was to quantify the impact of ProCCESs AWARE, Ambient Clinical Analytics, Rochester, MN, a novel acute care electronic medical record interface, on a range of care process and patient health outcome metrics in intensive care units (ICUs). ProCCESs AWARE is a novel acute care EMR interface that contains built-in tools for error prevention, practice surveillance, decision support and reporting. We compared outcomes before and after AWARE implementation using a prospective cohort and a historical control...
September 18, 2017: Journal of Medical Systems
https://www.readbyqxmd.com/read/28919249/dosimetric-predictors-for-acute-esophagitis-during-radiation-therapy-for-lung-cancer-results-of-a-large-statewide-observational-study
#15
Peter Paximadis, Matthew Schipper, Martha Matuszak, Mary Feng, Shruti Jolly, Thomas Boike, Inga Grills, Larry Kestin, Benjamin Movsas, Kent Griffith, Gregory Gustafson, Jean Moran, Teamour Nurushev, Jeffrey Radawski, Lori Pierce, James Hayman
PURPOSE: The purpose of this study is to identify dosimetric variables that best predict for acute esophagitis in patients treated for locally advanced non-small cell lung cancer in a prospectively accrued statewide consortium. METHODS AND MATERIALS: Patients receiving definitive radiation therapy for stage II-III non-small cell lung cancer within the Michigan Radiation Oncology Quality Consortium were included in the analysis. Dose-volume histogram data were analyzed to determine absolute volumes (cc) receiving doses from 10 to 60 Gy (V10, V20, V30, V40, V50, and V60), as well as maximum dose to 2 cc (D2cc), mean dose (MD), and generalized equivalent uniform dose (gEUD)...
July 19, 2017: Practical Radiation Oncology
https://www.readbyqxmd.com/read/28919125/multi-institution-analysis-of-infection-control-practices-identifies-the-subset-associated-with-best-surgical-site-infection-performance-a-texas-alliance-for-surgical-quality-collaborative-project
#16
Catherine H Davis, Lillian S Kao, Jason B Fleming, Thomas A Aloia
BACKGROUND: In an effort to reduce surgical site infection (SSI) rates, a large number of infection control practices (ICPs), including operating room attire policies, have been recommended. However, few have proven benefits and many are costly, time-consuming, and detrimental to provider morale. The goal of this multi-institution study was to determine which ICPs are associated with lower postoperative SSI rates. STUDY DESIGN: Twenty American College of Surgeons NSQIP and Texas Alliance for Surgical Quality-affiliated hospitals completed this Quality Improvement Assessment Board-approved study...
August 16, 2017: Journal of the American College of Surgeons
https://www.readbyqxmd.com/read/28918132/assessing-precision-bias-and-sigma-metrics-of-53-measurands-of-the-alinity-ci-system
#17
Sten Westgard, Victoria Petrides, Sharon Schneider, Marvin Berman, Jörg Herzogenrath, Anthony Orzechowski
Assay performance is dependent on the accuracy and precision of a given method. These attributes can be combined into an analytical Sigma-metric, providing a simple value for laboratorians to use in evaluating a test method's capability to meet its analytical quality requirements. Sigma-metrics were determined for 37 clinical chemistry assays, 13 immunoassays, and 3 ICT methods on the Alinity ci system. METHODS: Analytical Performance Specifications were defined for the assays, following a rationale of using CLIA goals first, then Ricos Desirable goals when CLIA did not regular the method, and then other sources if the Ricos Desirable goal was unrealistic...
September 13, 2017: Clinical Biochemistry
https://www.readbyqxmd.com/read/28917659/sonification-of-scalp-recorded-frequency-following-responses-ffrs-offers-improved-response-detection-over-conventional-statistical-metrics
#18
Gavin M Bidelman
BACKGROUND: The human frequency-following response (FFR) is a neurophonic potential used to examine the brain's encoding of complex sounds (e.g., speech) and monitor neuroplastic changes in auditory processing. Given the FFR's low amplitude (order of nanovolts), current conventions in literature recommend collecting several thousand trials to obtain a robust evoked response with adequate signal-to-noise ratio. NEW METHOD: By exploiting the spectrotemporal fidelity of the response, we examined whether auditory playbacks (i...
September 13, 2017: Journal of Neuroscience Methods
https://www.readbyqxmd.com/read/28916508/development-of-a-whole-slide-imaging-system-on-smartphones-and-evaluation-with-frozen-section-samples
#19
Hong Yu, Feng Gao, Liren Jiang, Shuoxin Ma
BACKGROUND: The aim was to develop scalable Whole Slide Imaging (sWSI), a WSI system based on mainstream smartphones coupled with regular optical microscopes. This ultra-low-cost solution should offer diagnostic-ready imaging quality on par with standalone scanners, supporting both oil and dry objective lenses of different magnifications, and reasonably high throughput. These performance metrics should be evaluated by expert pathologists and match those of high-end scanners. OBJECTIVE: The aim was to develop scalable Whole Slide Imaging (sWSI), a whole slide imaging system based on smartphones coupled with optical microscopes...
September 15, 2017: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/28915893/dosimetric-comparison-of-different-treatment-modalities-for-stereotactic-radiotherapy
#20
Shih-Ming Hsu, Yuan-Chun Lai, Chien-Chung Jeng, Chia-Ying Tseng
BACKGROUND: The modalities for performing stereotactic radiotherapy (SRT) on the brain include the cone-based linear accelerator (linac), the flattening filter-free (FFF) volumetric modulated arc therapy (VMAT) linac, and tomotherapy. In this study, the cone-based linac, FFF-VMAT linac, and tomotherapy modalities were evaluated by measuring the differences in doses delivered during brain SRT and experimentally assessing the accuracy of the output radiation doses through clinical measurements...
September 16, 2017: Radiation Oncology
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