keyword
MENU ▼
Read by QxMD icon Read
search

Central airway obstruction

keyword
https://www.readbyqxmd.com/read/29305603/assessing-airflow-sensitivity-to-healthy-and-diseased-lung-conditions-in-a-computational-fluid-dynamics-model-validated-in-vitro
#1
Bora Sul, Zachary Oppito, Shehan Jayasekera, Brian Vanger, Amy Zeller, Michael Morris, Kai Ruppert, Talissa Altes, Vineet Rakesh, Steven Day, Risa J Robinson, Jaques Reifman, Anders Wallqvist
Computational models are useful for understanding respiratory physiology. Crucial to such models are the boundary conditions specifying the flow conditions at truncated airway branches (terminal flow rates). However, most studies make assumptions about these values, which are difficult to obtain in vivo. We developed a computational fluid dynamics (CFD) model of airflows for steady expiration to investigate how terminal flows affect airflow patterns in respiratory airways. First, we measured in vitro airflow patterns in a physical airway model, using particle image velocimetry...
January 5, 2018: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/29302493/locally-advanced-asymptomatic-papillary-thyroid-cancer-presenting-with-retropharyngeal-lymph-node-metastasis-symptoms
#2
Roostam Kholmatov, Obinwanne Emejulu, Fadi Murad, Rizwan Aslam, Emad Kandil
Papillary thyroid cancer (PTC) rarely metastasizes to the retropharyngeal lymph nodes. Managing patients with locally advanced primary PTC and metastasis located in distant anatomical areas is challenging. Herein, we report a 56-year-old patient with locally advanced asymptomatic PTC, who presented with obstructive airway symptoms due to the metastatic retropharyngeal lymph node. The patient underwent simultaneous total thyroidectomy, central lymph node dissection, en bloc resection of strap muscle and left laryngeal nerve via cervical approach and transoral resection of the metastatic retropharyngeal lymph node...
December 2017: Gland Surgery
https://www.readbyqxmd.com/read/29291573/intratracheal-instillation-of-coal-and-coal-fly-ash-particles-in-mice-induces-dna-damage-and-translocation-of-metals-to-extrapulmonary-tissues
#3
Grethel León-Mejía, Mariana Nascimento Machado, Renata Tiemi Okuro, Luis F O Silva, Claudia Telles, Johnny Dias, Liana Niekraszewicz, Juliana Da Silva, João Antônio Pêgas Henriques, Walter Araujo Zin
Continuous exposure to coal mining particles can cause a variety of lung diseases. We aimed to evaluate the outcomes of exposure to detailed characterized coal and coal fly ash (CFA) particles on DNA, lung and extrapulmonary tissues. Coal samples (COAL11 and COAL16) and CFA samples (CFA11 and CFA16) were included in this study. Intending to enhance the combustion process COAL16 was co-fired with a mixture of fuel oil and diesel oil, producing CFA16. Male BALB/c mice were intratracheally instilled with coal and CFA particles...
December 29, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29291467/obstructive-sleep-apnea-as-a-risk-factor-associated-with-difficult-airway-management-a-narrative-review
#4
Siaw May Leong, Akhilesh Tiwari, Frances Chung, David T Wong
STUDY OBJECTIVE: The association between obstructive sleep apnea (OSA) and difficult airway had been studied in various clinical trials but the relationship between the two conditions has not been clearly established. The objective of this narrative review is to determine if OSA is a risk factor associated with difficult airway. DESIGN: The OVID Medline in process, Medline (vis Pub Med), EMBASE, Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews, Web of Science and SCOPUS were searched up to April 2016 using specific keywords...
December 29, 2017: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/29282351/marked-18-fuorine-fluorodeoxyglucose-fdg-avidity-of-an-intrapulmonary-typical-carcinoid-tumor-manifesting-as-a-bronchocele-in-an-asymptomatic-middle-aged-woman
#5
Camila Saadé-Yordán, Edward McBurney-Henriquez, Ricardo González-Santoni, Carmen Gurrea-Rosas, José Montalvo-Fitzpatrick, José A Maldonado-Vargas
BACKGROUND Intrapulmonary carcinoid tumors (ICTs) are malignant, slow-growing tumors classified as either: i) typical, less aggressive, well-differentiated tumors or ii) atypical, more aggressive, poorly-differentiated tumors. Most typical carcinoid tumors originate in the central airway and present with symptoms related to bronchial obstruction. In contrast, atypical carcinoids tend to occur more peripherally and are generally detected incidentally as a solitary pulmonary nodule (SPN). Typical carcinoid tumors usually do not exhibit increased metabolic activity on positron emission tomography with 18-fuorine-fluorodeoxyglucose (FDG PET) as would be expected for malignant tumors...
December 28, 2017: American Journal of Case Reports
https://www.readbyqxmd.com/read/29276878/the-use-of-nasal-trumpet-as-a-non-invasive-treatment-method-in-congenital-nasal-stenosis
#6
Özgür Kemal, Sinan Atmaca, Ayşe Bel-Çeçen, Berkan Düzgün, Hasibe Canan Aygün
Kemal Ö, Atmaca S, Bel-Çeçen A, Düzgün B, Aygün HC. The use of nasal trumpet as a non-invasive treatment method in congenital nasal stenosis. Turk J Pediatr 2017; 59: 210-213. Newborns and infants are dependent on nasal respiration and therefore, nasal obstructions may lead to life-threatening outcomes in this age group. Although the most common cause of nasal obstruction in newborns are choanal atresia, soft tissue edema, congenital nasal bone anomalies such as narrowness of the apertura piriformis and midnasal stenosis should be kept in mind...
2017: Turkish Journal of Pediatrics
https://www.readbyqxmd.com/read/29275133/inert-gas-washout-in-bronchiolitis-obliterans-following-hematopoietic-cell-transplantation
#7
Sylvia Nyilas, Luzia Baumeler, Michael Tamm, Jörg P Halter, Spasenija Savic, Insa Korten, Anja Meyer, Florian Singer, Jakob R Passweg, Philipp Latzin, Daiana Stolz
BACKGROUND: Bronchiolitis obliterans (BO) syndrome is a leading cause of chronic graft-versus-host disease (cGvHD) and is associated with mortality after allogeneic hematopoietic stem cell transplantation (alloHCT). Nitrogen multiple breath washout test (N2-MBW) measures ventilation inhomogeneity, a biomarker of central and peripheral airways obstruction. The aim of the study was to examine ventilation inhomogeneity according to cGvHD score and histologically defined BO. METHODS: This single center prospective cross-sectional study included 225 adults (mean age 52...
December 21, 2017: Chest
https://www.readbyqxmd.com/read/29273515/nasal-versus-oronasal-cpap-for-obstructive-sleep-apnea-treatment-a-meta-analysis
#8
Rafaela G S Andrade, Fernanda M Viana, Juliana A Nascimento, Luciano F Drager, Adriano Moffa, André R Brunoni, Pedro R Genta, Geraldo Lorenzi-Filho
BACKGROUND: Nasal continuous positive airway pressure (CPAP) is the gold standard treatment for obstructive sleep apnea (OSA). However, oronasal masks are frequently used in clinical practice. The aim of this study was to perform a meta-analysis of all randomized and non-randomized trials that compared nasal versus oronasal masks on CPAP level, residual apnea-hypopnea index (AHI) and CPAP adherence to treat OSA. METHODS: Cochrane Central Register of Controlled Trials, Medline and Web of Science were searched for relevant studies in any language with the following terms: "sleep apnea" AND "CPAP" OR "sleep apnea" AND "oronasal mask" OR "OSA" AND "oronasal CPAP" OR "oronasal mask" AND "adherence"...
December 19, 2017: Chest
https://www.readbyqxmd.com/read/29261588/bronchoscopic-management-of-central-airway-obstruction-secondary-to-rheumatoid-arthritis
#9
Sevak Keshishyan, Kassem Harris, Arjun Mohan, Monali Patil
No abstract text is available yet for this article.
January 2018: Journal of Bronchology & Interventional Pulmonology
https://www.readbyqxmd.com/read/29223509/neuropeptides-and-breathing-in-health-and-disease
#10
REVIEW
Katarzyna Kaczyńska, Dominika Zając, Piotr Wojciechowski, Ewelina Kogut, Małgorzata Szereda-Przestaszewska
Regulatory neuropeptides control and regulate breathing in physiological and pathophysiological conditions. While they have been identified in the neurons of major respiratory areas, they can be active not only at the central level, but also at the periphery via chemoreceptors, vagal afferents, or locally within lungs and airways. Some neuropeptides, such as leptin or substance P, are respiratory stimulants; others, such as neurotensin, produce variable effects on respiration depending on the site of application...
December 6, 2017: Pulmonary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/29222618/complex-sleep-apnea-after-full-night-and-split-night-polysomnography-the-greek-experience
#11
Katerina Baou, Charalampos Mermigkis, Aliki Minaritzoglou, Emmanouil Vagiakis
PURPOSE: Treatment-emergent central sleep apnea (TE-CSA) is defined as the emergence or persistence of central respiratory events during the initiation of positive airway pressure (PAP) without a back-up rate in obstructive sleep apnea (OSA) patients and after significant resolution of obstructive events. Previous studies have estimated a prevalence from 0.56 to 20.3%. The aim of this study was to establish the prevalence of TE-CSA in a Greek adult population. METHODS: One thousand fifty nine patients with newly diagnosed OSA, who were referred to the Sleep Disorders Center of Evangelismos Hospital of Athens over an 18-month period, were included in this study...
December 8, 2017: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/29214067/malignant-central-airway-obstruction
#12
REVIEW
Lakshmi Mudambi, Russell Miller, George A Eapen
This review comprehensively describes recent advances in the management of malignant central airway obstruction (CAO). Malignant CAO can be a dramatic and devastating manifestation of primary lung cancer or metastatic disease. A variety of diagnostic modalities are available to provide valuable information to plan a therapeutic intervention. Clinical heterogeneity in the presentation of malignant CAO provides opportunities to adapt and utilize endoscopic technology and tools in many ways. Mechanical debulking, thermal tools, cryotherapy and airway stents are methods and instruments used to rapidly restore airway patency...
September 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29197547/further-studies-of-unsuspected-emphysema-in-non-smoking-asthmatics-with-persistent-expiratory-airflow-obstruction
#13
Arthur F Gelb, Alfred Yamamoto, Eric K Verbeken, Mark J Schein, Roxanna Moridzadeh, Diem Tran, Christine Fraser, Richard Barbers, Wafaa Elatre, Michael N Koss, Eric F Glassy, Jay A Nadel
BACKGROUND: Previously, we and other investigators have described reversible loss of lung elastic recoil in acute and persistent loss in moderate-to-severe, chronic, treated asthmatics who never smoked, and its adverse effect on maximal expiratory airflow. In 4 consecutive autopsies, the pathophysiologic mechanism(s)has been unsuspected mild, diffuse, middle and upper lobe centrilobular emphysema. METHODS: We performed prospective studies (5-22 years) in 25(12F) chronic asthmatics age 55±15 yr who never smoked, with persistent moderate-to-severe expiratory obstruction...
November 29, 2017: Chest
https://www.readbyqxmd.com/read/29190622/classifying-apnea-of-prematurity-by-transcutaneous-electromyography-of-the-diaphragm
#14
Juliette V Kraaijenga, Gerard J Hutten, Cornelia G de Waal, Frans H de Jongh, Wes Onland, Anton H van Kaam
BACKGROUND: Treatment of apnea is highly dependent on the type of apnea. Chest impedance (CI) has inaccuracies in monitoring respiration, which compromises accurate apnea classification. Electrical activity of the diaphragm measured by transcutaneous electromyography (EMG) is feasible in preterm infants and might improve the accuracy of apnea classification. OBJECTIVES: To compare the accuracy of apnea classification based on diaphragmatic EMG (dEMG) and CI tracings in preterm infants...
December 1, 2017: Neonatology
https://www.readbyqxmd.com/read/29164122/changes-in-expression-of-the-clock-gene-in-obstructive-sleep-apnea-syndrome-patients-are-not-reverted-by-continuous-positive-airway-pressure-treatment
#15
Susana Moreira, Raquel Rodrigues, André B Barros, Nadja Pejanovic, Ana Neves-Costa, Dora Pedroso, Cláudia Pereira, Dina Fernandes, João Valença Rodrigues, Cristina Barbara, Luís Ferreira Moita
Purpose: Metabolic syndrome and cardiovascular disease are strongly associated with obstructive sleep apnea syndrome (OSAS), which causes substantial changes to normal circadian physiological functions, including metabolic pathways. Because core clock genes are known to be modulated by sleep/vigilance cycles, we asked whether the expression level of mRNA coding for clock genes is altered in non-treated OSAS patients and if it can be corrected by standard continuous positive airway pressure (CPAP) treatment...
2017: Frontiers in Medicine
https://www.readbyqxmd.com/read/29162360/sleep-disordered-breathing-in-heart-failure-the-state-of-the-art-after-the-serve-hf-trial
#16
REVIEW
João Carmo, Inês Araújo, Filipa Marques, Cândida Fonseca
Heart failure (HF) is one of the most prevalent conditions worldwide and despite therapeutic advances, its prognosis remains poor. Among the multiple comorbidities in HF, sleep-disordered breathing (SDB) is frequent and worsens the prognosis. Preliminary observational studies suggested that treatment of SDB could modify the prognosis of HF, and the issue has gained importance in recent years. The diagnosis of SDB is expensive, slow and suboptimal, and there is thus a need for screening devices that are easier to use and validated in this population...
November 18, 2017: Portuguese Journal of Cardiology: An Official Journal of the Portuguese Society of Cardiology
https://www.readbyqxmd.com/read/29151428/continuous-positive-airway-pressure-in-patients-with-obstructive-sleep-apnea-and-non-alcoholic-steatohepatitis-a-systematic-review-and-meta-analysis
#17
Gonzalo Labarca, Rodrigo Cruz, Jorge Jorquera
STUDY OBJECTIVES: Several studies have reported an association between obstructive sleep apnea (OSA) and several extra-pulmonary issues, such as arterial hypertension and insulin resistance. In recent years, the associations between OSA, non-alcoholic fatty liver disease, and non-alcoholic steatohepatitis (NASH) have been published; however, there is a gap between experimental and clinical studies regarding the efficacy of continuous positive airway pressure (CPAP) treatment in patient populations with these conditions...
November 15, 2017: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/29149469/cuffed-versus-uncuffed-endotracheal-tubes-for-general-anaesthesia-in-children-aged-eight-years-and-under
#18
REVIEW
Flavia A De Orange, Rebeca Gac Andrade, Andrea Lemos, Paulo Sgn Borges, José N Figueiroa, Pete G Kovatsis
BACKGROUND: Since the introduction of endotracheal intubation in paediatrics, uncuffed endotracheal tubes (ETTs) have been the standard of care for children under eight years old, based on the presumption that complications, particularly postoperative stridor, are higher with cuffed ETTs. The major disadvantages of uncuffed ETTs cited for this shift in procedure include the difficulty in achieving tidal volumes due to leakage around an uncuffed ETT. To seal the airway adequately, uncuffed tubes may need to be exchanged for another tube with a larger diameter, which sometimes requires several attempts before the appropriate size is found...
November 17, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29137224/role-of-the-inflammasome-in-chronic-obstructive-pulmonary-disease-copd
#19
Chiara Colarusso, Michela Terlizzi, Antonio Molino, Aldo Pinto, Rosalinda Sorrentino
Inflammation is central to the development of chronic obstructive pulmonary disease (COPD), a pulmonary disorder characterized by chronic bronchitis, chronic airway obstruction, emphysema, associated to progressive and irreversible decline of lung function. Emerging genetic and pharmacological evidence suggests that IL-1-like cytokines are highly detected in the sputum and broncho-alveolar lavage (BAL) of COPD patients, implying the involvement of the multiprotein complex inflammasome. So far, scientific evidence has focused on nucleotide-binding oligomerization domain-like receptors protein 3 (NLRP3) inflammasome, a specialized inflammatory signaling platform that governs the maturation and secretion of IL-1-like cytokines through the regulation of caspase-1-dependent proteolytic processing...
October 10, 2017: Oncotarget
https://www.readbyqxmd.com/read/29135910/sleep-disordered-breathing-in-children-with-recurrent-wheeze-asthma-a-single-centre-study
#20
Marco Zaffanello, Emma Gasperi, Laura Tenero, Michele Piazza, Angelo Pietrobelli, Luca Sacchetto, Franco Antoniazzi, Giorgio Piacentini
The relationship between asthma and sleep-disordered breathing is bidirectional due to common risk factors that promote airway inflammation. Obstructive sleep-disordered breathing and recurrent wheeze/asthma are conditions that involve the upper and the lower respiratory system, respectively. The aim of the present study was to investigate the sleep disordered breathing in children with recurrent wheeze/asthma. This was a retrospective study concerning children older than 2 years who underwent-between January 2014 and November 2016-an in-laboratory overnight polygraphic study...
November 14, 2017: Children
keyword
keyword
11945
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"