keyword
MENU ▼
Read by QxMD icon Read
search

itaconate

keyword
https://www.readbyqxmd.com/read/28629058/photo-induced-surface-grafting-of-phosphorylcholine-containing-copolymers-onto-mesoporous-silica-nanoparticles-for-controlled-drug-delivery
#1
Liucheng Mao, Meiying Liu, Long Huang, Dazhuang Xu, Qing Wan, Guangjian Zeng, Yanfeng Dai, Yuanqing Wen, Xiaoyong Zhang, Yen Wei
Surface modification of mesoporous silica nanoparticles (MSNs) with functional polymers has become one of the most interest topics over the last decade. Among various surface modification strategies, surface-initiated atom transfer radical polymerization (ATRP) has been regarded as one of the most effective methods. However, the typical ATRP strategy is relied on the transition metal ions and their organic ligands as the polymerization catalyst systems. In this work, a novel surface-initiated ATRP method was established for surface functionalization of MSNs using 10-Phenylphenothiazine (PTH) as the catalyst, 2-methacryloyloxyethyl phosphorylcholine (MPC) and itaconic acid (IA) as the monomers...
October 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28620888/design-of-isoniazid-smart-nanogel-by-gamma-radiation-induced-template-polymerization-for-biomedical-application
#2
Samia M Omar, Nabila A Maziad, Nourhan M El-Tantawy
PURPOSE: Preparation of Isoniazid (INH) loaded nanogel particles using gamma radiation as safe, simple, cheap and reproducible technique for promoting mycobacterial killing in a lower-dose system aiming in developing of drug resistance. METHODS: Polymeric pH-sensitive nanogels were prepared by gamma radiation-induced polymerization of Acrylic acid (AAc) or Itaconic acid (IA), in aqueous solution of polyvinylpyrrolidone (PVP), as template polymer. The prepared nanogels were utilized for encapsulation of INH...
June 15, 2017: Pharmaceutical Research
https://www.readbyqxmd.com/read/28599860/molecularly-imprinted-nanoparticles-grafted-to-porous-silica-as-chiral-selectors-in-liquid-chromatography
#3
Raquel Gutierrez-Climente, Alberto Gomez-Caballero, Antonio Guerreiro, Deiene Garcia-Mutio, Nora Unceta, M Aránzazu Goicolea, Ramon J Barrio
The work presented here explores the grafting of molecularly imprinted nanoparticles (MIN) on silica beads for the development of new chiral stationary phases (CSP). Both solid-phase imprinting and precipitation polymerisation were tested for MIN synthesis though the latter approach was the only one that provided efficient chiral selectors. MIN particles were prepared by iniferter polymerisation initiated by UV radiation, using itaconic acid as functional monomer and ethylene dimethacrylate as cross-linker...
June 3, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/28559214/novel-salicylic-acid-based-chemically-crosslinked-ph-sensitive-hydrogels-as-potential-drug-delivery-systems
#4
Bahar Demirdirek, Kathryn E Uhrich
In this work, salicylic acid (SA), a non-steroidal anti-inflammatory, was chemically incorporated into hydrogel systems to achieve sustained SA release profiles. With its anti-inflammatory properties, sustained release of SA would be relevant for treating diseases such as diabetes and cancer. In this work, SA was chemically incorporated into hydrogel systems via covalent attachment to an itaconate moiety followed by UV-initiated crosslinking using acrylic acid and poly(ethylene glycol) diacrylate. The chemical composition of the hydrogel system was confirmed using FT-IR spectroscopy...
May 27, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/28550772/production-of-itaconic-acid-by-biotransformation-of-wheat-bran-hydrolysate-with-aspergillus-terreus-cicc40205-mutant
#5
Xuefeng Wu, Qing Liu, Yongdong Deng, Jinghong Li, Xiaoju Chen, Yongzhong Gu, Xijun Lv, Zhi Zheng, Shaotong Jiang, Xingjiang Li
The replacement of the carbon source in the microbial production of itaconic acid (IA) with economic alternatives has attracted significant attention. In this study, an Aspergillus terreus CICC40205 mutant was used to increase the IA titer and decrease the citric acid titer in the wheat bran hydrolysate compared with the parental strain. The results showed that the IA titer was increased by 33.4%, whereas the citric acid titer was decreased by 75.8%, and were in accordance with those of the improved pathway of co-metabolism of glucose and xylose according to the metabolic flux analysis...
May 17, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28538198/protein-and-metabolic-engineering-for-the-production-of-organic-acids
#6
Jingjing Liu, Jianghua Li, Hyun-Dong Shin, Long Liu, Guocheng Du, Jian Chen
Organic acids are natural metabolites of living organisms. They have been widely applied in the food, pharmaceutical, and bio-based materials industries. In recent years, biotechnological routes to organic acids production from renewable raw materials have been regarded as very promising approaches. In this review, we provide an overview of current developments in the production of organic acids using protein and metabolic engineering strategies. The organic acids include propionic acid, pyruvate, itaconic acid, succinic acid, fumaric acid, malic acid and citric acid...
September 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28533815/efficient-itaconic-acid-production-from-glycerol-with-ustilago-vetiveriae-tz1
#7
Thiemo Zambanini, Hamed Hosseinpour Tehrani, Elena Geiser, Dorothee Merker, Sarah Schleese, Judith Krabbe, Joerg M Buescher, Guido Meurer, Nick Wierckx, Lars M Blank
BACKGROUND: The family of Ustilaginaceae is known for their capability to naturally produce industrially valuable chemicals from different carbon sources. Recently, several Ustilaginaceae were reported to produce organic acids from glycerol, which is the main side stream in biodiesel production. RESULTS: In this study, we present Ustilago vetiveriae as new production organism for itaconate synthesis from glycerol. In a screening of 126 Ustilaginaceae, this organism reached one of the highest titers for itaconate combined with a high-glycerol uptake rate...
2017: Biotechnology for Biofuels
https://www.readbyqxmd.com/read/28532048/surface-grafting-of-eu-3-doped-luminescent-hydroxyapatite-nanomaterials-through-metal-free-light-initiated-atom-transfer-radical-polymerization-for-theranostic-applications
#8
Guangjian Zeng, Meiying Liu, Ruming Jiang, Chunning Heng, Qiang Huang, Liucheng Mao, Junfeng Hui, Fengjie Deng, Xiaoyong Zhang, Yen Wei
We reported a simple and efficient method to prepare the hydrophilic luminescent HAp polymer nanocomposites through the combination of ligand exchange and metal free light initiated surface-initiated atom transfer radical polymerization (SI-ATRP) using 10-phenylphenothiazine (PTH) as organic catalyst and 2-methacryloyloxyethyl phosphorylcholine (MPC) and itaconic acid (IA) as monomers. The biological imaging and drug delivery performance of HAp-poly(MPC-IA) nanorods were examined to evaluate their potential for biomedical applications...
August 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28508183/compositional-design-and-taguchi-optimization-of-hardness-properties-in-silicone-based-ocular-lenses
#9
Mohammad Hanifeh, Mojgan Zandi, Parvin Shokrollahi, Mohammad Atai, Ebrahim Ghafarzadeh, Fahimeh Askari
A multi-component acrylate-based copolymer system especially designed for application as ocular lenses is developed through free-radical, bulk polymerization of a system containing hydroxyethyl methacrylate, methyl methacrylate, triethylene glycol dimethacrylate, dimethyl itaconate, 3-(trimethoxysilyl) propylmethacrylate, Polyhedraloligomeric silsesquioxane-acrylate (POSS-acrylate) and AIBN as an initiator. The progress of the reaction was monitored by Fourier transform infrared spectroscopy (FTIR). The effect of increasing concentration of the components on the hardness of the synthesized lenses was measured by Shore Durometer before and after immersion in PBS solutions...
May 15, 2017: Progress in biomaterials
https://www.readbyqxmd.com/read/28452785/adsorption-of-methylene-blue-by-using-novel-chitosan-g-itaconic-acid-bentonite-nanocomposite-equilibrium-and-kinetic-study
#10
Farzaneh Shakib, Ahmad Dadvand Koohi, Arash Kamran Pirzaman
In this study, novel chitosan-g-itaconic acid/bentonite (CTS-g-IA/BT) and chitosan/bentonite (CTS/BT) nanocomposites were synthesized for adsorption of methylene blue (MB) from aqueous solution. The process was pH-sensitive and maximum sorption was obtained at pH 6 (CTS-g-IA/BT) and 7 (CTS/BT) in 76 h agitation time using 0.03 g of nanocomposites for 50 mL of MB solution. The results showed that in pH less than 6, the adsorption capacity of CTS-g-IA/BT nanocomposite due to the existence of IA monomer is less than that of CTS/BT nanocomposite...
April 2017: Water Science and Technology: a Journal of the International Association on Water Pollution Research
https://www.readbyqxmd.com/read/28450887/process-relevant-screening-of-cellulolytic-organisms-for-consolidated-bioprocessing
#11
Elena Antonov, Ivan Schlembach, Lars Regestein, Miriam A Rosenbaum, Jochen Büchs
BACKGROUND: Although the biocatalytic conversion of cellulosic biomass could replace fossil oil for the production of various compounds, it is often not economically viable due to the high costs of cellulolytic enzymes. One possibility to reduce costs is consolidated bioprocessing (CBP), integrating cellulase production, hydrolysis of cellulose, and the fermentation of the released sugars to the desired product into one process step. To establish such a process, the most suitable cellulase-producing organism has to be identified...
2017: Biotechnology for Biofuels
https://www.readbyqxmd.com/read/28440059/production-of-itaconic-acid-from-pentose-sugars-by-aspergillus-terreus
#12
Badal C Saha, Gregory J Kennedy, Nasib Qureshi, Michael J Bowman
Itaconic acid (IA), an unsaturated 5-carbon dicarboxylic acid, is a building block platform chemical that is currently produced industrially from glucose by fermentation with Aspergillus terreus. However, lignocellulosic biomass has potential to serve as low cost source of sugars for production of IA. Research needs to be performed to find a suitable A. terreus strain that can use lignocellulose derived pentose sugars and produce IA. One hundred A. terreus strains were evaluated for the first time for production of IA from xylose and arabinose...
April 25, 2017: Biotechnology Progress
https://www.readbyqxmd.com/read/28425297/new-approaches-for-itaconic-acid-production-bottlenecks-and-possible-remedies
#13
Richa Bafana, R A Pandey
Currently, growing attention is being devoted to the conversion of biomass into value-added products, such as itaconic acid (IA), which is considered as the cleanest alternative to petroleum-based acrylic acid. IA is an unsaturated dicarboxylic acid that is used as a building block chemical for the production of several value-added products such as poly-itaconic acid. IA and its derivatives have a wide range of potential applications in textile, paint, pharmaceutical and chemical industries. Presently, industries are producing IA on the large scale by fermentation from glucose...
April 20, 2017: Critical Reviews in Biotechnology
https://www.readbyqxmd.com/read/28415494/investigation-on-au-nano-incorporated-ph-sensitive-itaconic-acid-acrylic-acid-triethylene-glycol-based-polymeric-biocompatible-hydrogels
#14
M Sakthivel, D S Franklin, S Sudarsan, G Chitra, S Guhanathan
The pH-sensitive gold nano hydrogel based on itaconic acid, acrylic acid and triethylene glycol (GIAT) has been prepared by free radical polymerization viz. organic solventless approach with different monomer ratios. The nature of bonding and structural identification of GIAT hydrogels were characterized by FT-IR spectroscopy. The surface morphology of gold gel was examined using scanning electron microscopy (SEM). In addition, transmission electron microscopy (TEM) was used to identify the size of gold nano particles...
June 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28385524/itaconic-acid-grafted-carboxymethyl-chitosan-and-its-nanoparticles-preparation-characterization-and-evaluation
#15
Yanyan Yin, Qifeng Dang, Chengsheng Liu, Jingquan Yan, Dongsu Cha, Zhenzhen Yu, Yachan Cao, Yan Wang, Bing Fan
This work aims to synthesize a novel itaconic acid (IA) grafted carboxymethyl chitosan (PICMCS), and further fabricate its nanoparticles for potential biomedical applications. First, PICMCS was prepared via free-radical polymerization of IA monomer, in the presence of ammonium persulfate as an initiator and nitrogen as a protector. Its chemical structure was confirmed by FTIR and (1)H NMR. The IA substitution degree calculated by elemental analysis data was 1.85, implying that IA was successfully grafted to carboxymethyl chitosan (CMCS)...
April 4, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28366527/engineering-efficient-production-of-itaconic-acid-from-diverse-substrates-in-escherichia-coli
#16
Peiching Chang, Grey S Chen, Hsiang-Yuan Chu, Ken W Lu, Claire R Shen
Itaconic acid is an excellent polymeric precursor with wide range of industrial applications. Here, efficient production of itaconate from various renewable substrates was demonstrated by engineered Escherichia coli. Limitation in the itaconate precursor supply was revealed by feeding of the key intermediate citrate to the culture medium. Efforts of enhancing the cis-aconitate flux and preserving the isocitrate pool increased itaconate productivity by nearly 100-fold. Elimination of the isocitrate lyase lowered the itaconate production by 10-30%, suggesting the potential positive role of glyoxylate shunt...
March 31, 2017: Journal of Biotechnology
https://www.readbyqxmd.com/read/28356443/a-microrna93-irf9-irg1-itaconic-acid-pathway-modulates-m2-like-macrophage-polarization-to-revascularize-ischemic-muscle
#17
Vijay Chaitanya Ganta, Min Hyub Choi, Anna Kutateladze, Todd E Fox, Charles R Farber, Brian H Annex
Background -Currently no therapies exist for treating, and improving outcomes in patients with severe peripheral arterial disease (PAD). MicroRNA93 (miR93) has been shown to favorably modulate angiogenesis and reduce tissue loss in genetic PAD models. However, the cell specific function, downstream mechanisms or signaling involved in miR93 mediated ischemic muscle neovascularization is not clear. Macrophages were best known to modulate arteriogenic response in PAD and the extent of arteriogenic response induced by macrophages is dependent on greater M2 to M1-activation/polarization state...
March 29, 2017: Circulation
https://www.readbyqxmd.com/read/28356226/surfactants-from-itaconic-acid-toxicity-to-hacat-keratinocytes-in-vitro-micellar-solubilization-and-skin-permeation-enhancement-of-hydrocortisone
#18
Angela Abruzzo, Nicola Armenise, Federica Bigucci, Teresa Cerchiara, Mireia Broch Gösser, Chiara Samorì, Paola Galletti, Emilio Tagliavini, David M Brown, Helinor J Johnston, Teresa F Fernandes, Barbara Luppi
One of the most widely used approaches for improving drug permeation across the stratum corneum barrier of the skin is the use of chemical penetration enhancers, such as surfactants. In this study, two anionic surfactants, named C12-OPK and C18-OPK, were synthesized via condensation of itaconic acid and fatty amines, with C12 and C18 alkyl chains, respectively. Assessment of impacts on HaCaT keratinocyte cell viability was used as indicator of their potential to cause skin irritation 24h post exposure (Alamar Blue assay)...
March 27, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/28344094/controlled-release-of-antibiotic-amoxicillin-drug-using-carboxymethyl-cellulose-cl-poly-lactic-acid-co-itaconic-acid-hydrogel
#19
S Sood, Vinod Kumar Gupta, Shilpi Agarwal, Kamal Dev, Deepak Pathania
In this paper, microwave assisted preparation of carboxymethyl cellulose-cl-poly(lactic acid-co-itaconic acid) (CMC-cl-P(LA-co-IA)) hydrogel was reported via facile graft copolymerization using N,N(1)-methylene-bis-acrylamide (MBA) and potassium persulphate as cross linker and initiator. Different reaction parameters were optimized to achieve good yield. The formation of hydrogel was confirmed by characterization techniques such as Fourier transform infrared spectroscopy, field emission scanning electron microscopy, X-ray diffraction, thermo gravimetric analysis, transmission electron microscopy etc...
August 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28332572/xeno-free-culture-of-human-pluripotent-stem-cells-on-oligopeptide-grafted-hydrogels-with-various-molecular-designs
#20
Yen-Ming Chen, Li-Hua Chen, Meng-Pei Li, Hsing-Fen Li, Akon Higuchi, S Suresh Kumar, Qing-Dong Ling, Abdullah A Alarfaj, Murugan A Munusamy, Yung Chang, Giovanni Benelli, Kadarkarai Murugan, Akihiro Umezawa
Establishing cultures of human embryonic (ES) and induced pluripotent (iPS) stem cells in xeno-free conditions is essential for producing clinical-grade cells. Development of cell culture biomaterials for human ES and iPS cells is critical for this purpose. We designed several structures of oligopeptide-grafted poly (vinyl alcohol-co-itaconic acid) hydrogels with optimal elasticity, and prepared them in formations of single chain, single chain with joint segment, dual chain with joint segment, and branched-type chain...
March 23, 2017: Scientific Reports
keyword
keyword
119439
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"