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https://www.readbyqxmd.com/read/28637710/the-combined-action-of-duplicated-boron-transporters-is-required-for-maize-growth-in-boron-deficient-conditions
#1
Mithu Chatterjee, Qiujie Liu, Caitlin Menello, Mary Galli, Andrea Gallavotti
The micronutrient boron is essential in maintaining the structure of plant cell walls and is critical for high yields in crop species. Boron can move into plants by diffusion or by active and facilitated transport mechanisms. We recently showed that mutations in the maize boron efflux transporter ROTTEN EAR (RTE) cause severe developmental defects and sterility. RTE is part of a small gene family containing five additional members (RTE2-RTE6) that show tissue specific expression. The close paralogous gene RTE2 encodes a protein with 95% amino acid identity with RTE and is similarly expressed in shoot and root cells surrounding the vasculature...
June 21, 2017: Genetics
https://www.readbyqxmd.com/read/28631896/boric-acid-gel-as-local-drug-delivery-in-the-treatment-of-class-ii-furcation-defects-in-chronic-periodontitis-a-randomized-controlled-clinical-trial
#2
Sandeep Singhal, Avani Raju Pradeep, Dharmendra Kanoriya, Shruti Garg, Vibhuti Garg
AIM: Boric acid (BA) exhibits antibacterial, anti-inflammatory, as well as osteoblastic, activity. The aim of the present study was to explore the efficacy of 0.75% BA gel as a local drug-delivery system in adjunct to scaling and root planing (SRP) for the treatment of class II furcation defects in comparison with placebo gel. METHODS: A total of 48 mandibular class II furcation defects were randomized and treated with either 0.75% BA gel or placebo gel. Clinical parameters were recorded at baseline, 3 months, and 6 months, while radiographic parameters were recorded at baseline and 6 months...
June 20, 2017: Journal of Investigative and Clinical Dentistry
https://www.readbyqxmd.com/read/28624888/steady-state-pharmacokinetics-of-mycophenolic-acid-in-renal-transplant-patients-exploratory-analysis-of-the-effects-of-cyclosporine-recipients-and-donors-abcc2-gene-variants-and-their-interactions
#3
N Božina, Z Lalić, S Nađ-Škegro, A Borić-Bilušić, T Božina, Ž Kaštelan, V Trkulja
PURPOSE: The study aims to evaluate the impact of recipients' and donors' polymorphisms in multidrug resistance-associated protein 2 (MRP2) gene ABCC2 -24C>T and 1249G>A on disposition of mycophenolic acid (MPA) and their interaction with cyclosporine (CsA) (compared to tacrolimus, TAC) in stable de novo adult renal transplant patients of Croatian origin. METHODS: A total of 68 recipient-donor pairs were genotyped. Steady-state pharmacokinetics of MPA was assessed by the model-independent method...
June 18, 2017: European Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/28623494/the-effects-of-pesticides-on-morphology-viability-and-germination-of-blackberry-rubus-glaucus-benth-and-tree-tomato-solanum-betaceum-cav-pollen-grains
#4
Flavio Padilla, Norman Soria, Abrahan Oleas, Darwin Rueda, Bangeppagari Manjunatha, Rajesh R Kundapur, Naga Raju Maddela, Bugude Rajeswari
The objective of this study was to determine the effect of application of pesticides on morphology, viability, and germination of pollen grains of Blackberry (Rubus glaucus Benth.) and Tree tomato (Solanum betaceum Cav.). The study was performed at Patate, Tungurahua province, Ecuador and was divided into two phases. Phase one dedicated to the study of morphology, viability, and identification of nutrient solution for better germination of pollen grains and phase two for the analysis of the effect of conventional, organic, and biological pesticides on pollen grain germination and pollen tube length...
July 2017: 3 Biotech
https://www.readbyqxmd.com/read/28595910/not-all-boronic-acids-with-a-five-membered-cycle-induce-tremor-neuronal-damage-and-decreased-dopamine
#5
Maribel Pérez-Rodríguez, Esperanza García-Mendoza, Eunice D Farfán-García, Bhaskar C Das, Fabiola J Ciprés-Flores, José G Trujillo-Ferrara, Feliciano Tamay-Cach, Marvin A Soriano-Ursúa
Several striatal toxins can be used to induce motor disruption. One example is MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine), whose toxicity is accepted as a murine model of parkinsonism. Recently, 3-Thienylboronic acid (3TB) was found to produce motor disruption and biased neuronal damage to basal ganglia in mice. The aim of this study was to examine the toxic effects of four boronic acids with a close structural relationship to 3TB (all having a five-membered cycle), as well as boric acid and 3TB. These boron-containing compounds were compared to MPTP regarding brain access, morphological disruption of the CNS, and behavioral manifestations of such disruption...
June 6, 2017: Neurotoxicology
https://www.readbyqxmd.com/read/28595011/acidities-under-the-perspective-of-energy-decomposition-analysis
#6
Rodrigo Meneghetti Pontes, Ernani Abicht Basso, Danilo Eduardo Martins, Rafael Martinez Madeira
The rationalization of acid/base behavior is a central concern for chemistry and related fields. In this work, we describe an alternative approach towards the understanding of gas phase acidities based on the Localized Molecular Orbital Energy Decomposition Analysis (LMOEDA) method. Upon partitioning the molecules (and the corresponding anions) over the X-OH (or X-O-) bond, we have observed a perfect correlation between the interaction energy of the two fragments and the acidity, as given by the energy difference between the anion and the neutral molecule...
June 8, 2017: Journal of Physical Chemistry. A
https://www.readbyqxmd.com/read/28592646/loci-contributing-to-boric-acid-toxicity-in-two-reference-populations-of-drosophila-melanogaster
#7
Michael A Najarro, Jennifer L Hackett, Stuart J Macdonald
Populations maintain considerable segregating variation in the response to toxic, xenobiotic compounds. To identify variants associated with resistance to boric acid, a commonly-used household insecticide with a poorly understood mechanism of action, we assayed thousands of individuals from hundreds of strains. Using the Drosophila Synthetic Population Resource (DSPR), a multi-parental population (MPP) of inbred genotypes, we mapped six QTL to short genomic regions containing few protein-coding genes (3-188), allowing us to identify plausible candidate genes underlying resistance to boric acid toxicity...
June 7, 2017: G3: Genes—Genomes—Genetics
https://www.readbyqxmd.com/read/28575889/a-very-unique-case-of-boric-acid-intoxication-with-very-high-magnitude-rhabdomyolysis
#8
Ugo Vertolli, Marianna Alessi, Elena Naso, Agostino Naso, Lorenzo A Calò
No abstract text is available yet for this article.
May 2017: Iranian Journal of Kidney Diseases
https://www.readbyqxmd.com/read/28569603/clinical-accuracy-of-point-of-care-urine-culture-in-general-practice
#9
Anne Holm, Gloria Cordoba, Tina Møller Sørensen, Lisbeth Rem Jessen, Niels Frimodt-Møller, Volkert Siersma, Lars Bjerrum
OBJECTIVE: To assess the clinical accuracy (sensitivity (SEN), specificity (SPE), positive predictive value and negative predictive value) of two point-of-care (POC) urine culture tests for the identification of urinary tract infection (UTI) in general practice. DESIGN: Prospective diagnostic accuracy study comparing two index tests (Flexicult™ SSI-Urinary Kit or ID Flexicult™) with a reference standard (urine culture performed in the microbiological department)...
June 1, 2017: Scandinavian Journal of Primary Health Care
https://www.readbyqxmd.com/read/28548501/structure-and-properties-of-sodium-enneaborate-na2-b8o11-oh-4-%C3%A2-b-oh-3%C3%A2-2h2o
#10
Doinita Neiner, Yulia V Sevryugina, Larry S Harrower, David M Schubert
Millions of tons of sodium borates are used annually by global industries in diverse applications important to modern society. The Na2O-B2O3-H2O phase diagram in the 0-100 °C temperature range contains 13 unique hydrated crystalline sodium borates, including five important industrial products. Structures were previously reported for each of these except for that having the highest boron content, known as sodium enneaborate, Na4B18O29·11H2O or 2Na2O·9B2O3·11H2O (1). Here we report the single-crystal structure of 1, revealing the structural formula Na2[B8O11(OH)4]·B(OH)3·2H2O, and describe some of its properties and relationships to other sodium borates...
May 26, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/28547785/alkynyl-n-nosylhydrazones-easy-decomposition-to-alknynl-diazomethanes-and-application-for-allene-synthesis
#11
Xihe Bi, Yang Yang, Zhaohong Liu, Alessio Porta, Giuseppe Zanoni
The dissociation of N-tosylhydrazones is a safe and convenient method for the generation of donor carbenes. However, alkynyl carbenes cannot be isolated by this route because they readily undergo intramolecular cyclization to pyrazoles as soon as formed from alkynyl N-tosylhydrazones. Herein we report the use of alkynyl N-nosylhydrazones for the in situ generation of alkynyl carbenes and their coupling reaction with boronic acids under metal-free conditions, giving rise to a wide array of di- and trisubstituted allenes...
May 26, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28512317/structural-determinants-of-neosartorya-fischeri-antifungal-protein-nfap-for-folding-stability-and-antifungal-activity
#12
László Galgóczy, Attila Borics, Máté Virágh, Hargita Ficze, Györgyi Váradi, Zoltán Kele, Florentine Marx
The recent global challenges to prevent and treat fungal infections strongly demand for the development of new antifungal strategies. The structurally very similar cysteine-rich antifungal proteins from ascomycetes provide a feasible basis for designing new antifungal molecules. The main structural elements responsible for folding, stability and antifungal activity are not fully understood, although this is an essential prerequisite for rational protein design. In this study, we used the Neosartorya fischeri antifungal protein (NFAP) to investigate the role of the disulphide bridges, the hydrophobic core, and the N-terminal amino acids in the formation of a highly stable, folded, and antifungal active protein...
May 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28504432/control-of-male-aedes-albopictus-skuse-diptera-culicidae-using-boric-acid-sugar-bait-and-its-impact-on-female-fecundity-and-fertility
#13
Fei Wang, Yuan Shen, Daniel Dixon, Rui-De Xue
No abstract text is available yet for this article.
June 2017: Journal of Vector Ecology: Journal of the Society for Vector Ecology
https://www.readbyqxmd.com/read/28479241/ototoxicity-of-boric-acid-powder-in-a-rat-animal-model
#14
Murat Salihoglu, Salim Dogru, Enver Cesmeci, Halil Caliskan, Onuralp Kurt, Zafer Kuçukodaci, Atila Gungor
INTRODUCTION: Boric acid, which has antiseptic and acidic properties, is used to treat external and middle ear infections. However, we have not found any literature about the effect of boric acid powder on middle ear mucosa and inner ear. OBJECTIVE: The purpose of this study is to investigate possible ototoxic effects of boric acid powder (BAP) on cochlear outer hair cell function and histological changes in middle ear mucosa in a rat animal model. METHODS: Twenty healthy, mature Wistar albino rats were used in this study...
April 22, 2017: Brazilian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/28474437/clinical-efficacy-of-subgingivally-delivered-0-75-boric-acid-gel-as-an-adjunct-to-mechanotherapy-in-chronic-periodontitis-a-randomized-controlled-clinical-trial
#15
Dharmendra Kanoriya, Sandeep Singhal, Vibhuti Garg, Avani R Pradeep, Shruti Garg, Amit Kumar
AIM: Borinic acid quinoline esters are a recently-identified class of new antibacterial and anti-inflammatory compounds known to inhibit osteoclastic bone resorption. They have proposed to have osteostimulative properties by causing osteoblast differentiation in vivo and in vitro. The purpose of this double-masked, randomized, controlled clinical trial was to evaluate the effects of the subgingival delivery of boric acid gel as an adjunct to scaling and root planing (SRP) on clinical and radiographic parameters, and compare this method with SRP plus placebo gel alone in chronic periodontitis (CP) patients...
May 5, 2017: Journal of Investigative and Clinical Dentistry
https://www.readbyqxmd.com/read/28460310/synthesis-characterization-molecular-docking-and-in%C3%A2-vitro-antimalarial-properties-of-new-carboxamides-bearing-sulphonamide
#16
D I Ugwu, U C Okoro, P O Ukoha, S Okafor, A Ibezim, N M Kumar
Sulphonamides and carboxamides have shown large number of pharmacological properties against different types of diseases among which is malaria. Twenty four new carboxamide derivatives bearing benzenesulphonamoyl alkanamides were synthesized and investigated for their in silico and in vitro antimalarial and antioxidant properties. The substituted benzenesulphonyl chlorides (1a-c) were treated with various amino acids (2a-h) to obtain the benzenesulphonamoyl alkanamides (3a-x) which were subsequently treated with benzoyl chloride to obtain the N-benzoylated derivatives (5a-f, i-n and q-v)...
April 17, 2017: European Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/28451986/bt-proteins-have-no-detrimental-effects-on-larvae-of-the-green-lacewing-chrysopa-pallens-rambur-neuroptera-chrysopidae
#17
I Ali, S Zhang, M S Muhammad, M Iqbal, J-J J-J Cui
Biosafety of a genetically modified crop is required to be assessed prior to its commercialization. For this, a suitable artificial diet was developed and used to establish a dietary exposure test for assessing the toxicity of midgut-active Bt insecticidal proteins on Chrysopa pallens (Rambur). Subsequently, this dietary exposure test was used to evaluate the toxicity of the proteins Cry1Ab, Cry1Ac, Cry1Ah, Cry1Ca, Cry1F, Cry2Aa, Cry2Ab, and Vip3Aa on C. pallens larvae. Temporal stability, bioactivity, and the intake of the insecticidal proteins were confirmed by enzyme-linked immunosorbent assay and a sensitive-insect bioassay...
April 28, 2017: Neotropical Entomology
https://www.readbyqxmd.com/read/28443835/effect-of-boric-acid-versus-conventional-irrigation-solutions-on-the-bond-strength-between-fiber-post-and-root-dentin
#18
Ahmet Kursad Culhaoglu, Erdal Özcan, Mehmet Ali Kilicarslan, Emre Seker
PURPOSE: To compare the effect of boric acid solutions of different percentages to conventional irrigation solutions on the adhesive bond strength between fiber posts and radicular dentin surface with different cement types. MATERIALS AND METHODS: One hundred fifteen extracted human incisors were endodontically instrumented to a length of 14-15 mm, and 12-mm post spaces were prepared with specific drills. Cylindrical fiber posts (Panavia Post) were luted with two different composite cements (Panavia F 2...
April 25, 2017: Journal of Adhesive Dentistry
https://www.readbyqxmd.com/read/28441323/gold-nanoplates-for-a-localized-surface-plasmon-resonance-based-boric-acid-sensor
#19
Marlia Morsin, Muhamad Mat Salleh, Akrajas Ali Umar, Mohd Zainizan Sahdan
Localized surface plasmon resonance (LSPR) properties of metallic nanostructures, such as gold, are very sensitive to the dielectric environment of the material, which can simply be adjusted by changing its shape and size through modification of the synthesizing process. Thus, these unique properties are very promising, particularly for the detection of various types of chemicals, for example boric acid which is a non-permitted preservative employed in food preparations. For the sensing material, gold (Au) nanoplates with a variety of shapes, i...
April 25, 2017: Sensors
https://www.readbyqxmd.com/read/28429621/the-distribution-and-movement-of-american-cockroaches-in-urban-niches-of-new-orleans
#20
John C Carlson, Felicia A Rabito, Derek Werthmann, Mark Fox
American cockroaches are an important source of household allergens in tropical and semitropical climates. To determine which outdoor niches produce American cockroaches, traps were placed at 40 homes in New Orleans to collect nymphs. Nymphs were collected from the sewers, yards, and within the homes themselves. To compare sewers and yards as sources of cockroaches entering homes, adult cockroaches were collected, marked, and released into yards and sewers. No sewer-released cockroaches were collected in homes...
April 1, 2017: Clinical Pediatrics
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