keyword
MENU ▼
Read by QxMD icon Read
search

Boric acid

keyword
https://www.readbyqxmd.com/read/28512317/structural-determinants-of-neosartorya-fischeri-antifungal-protein-nfap-for-folding-stability-and-antifungal-activity
#1
László Galgóczy, Attila Borics, Máté Virágh, Hargita Ficze, Györgyi Váradi, Zoltán Kele, Florentine Marx
The recent global challenges to prevent and treat fungal infections strongly demand for the development of new antifungal strategies. The structurally very similar cysteine-rich antifungal proteins from ascomycetes provide a feasible basis for designing new antifungal molecules. The main structural elements responsible for folding, stability and antifungal activity are not fully understood, although this is an essential prerequisite for rational protein design. In this study, we used the Neosartorya fischeri antifungal protein (NFAP) to investigate the role of the disulphide bridges, the hydrophobic core, and the N-terminal amino acids in the formation of a highly stable, folded, and antifungal active protein...
May 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28504432/control-of-male-aedes-albopictus-skuse-diptera-culicidae-using-boric-acid-sugar-bait-and-its-impact-on-female-fecundity-and-fertility
#2
Fei Wang, Yuan Shen, Daniel Dixon, Rui-De Xue
No abstract text is available yet for this article.
June 2017: Journal of Vector Ecology: Journal of the Society for Vector Ecology
https://www.readbyqxmd.com/read/28479241/ototoxicity-of-boric-acid-powder-in-a-rat-animal-model
#3
Murat Salihoglu, Salim Dogru, Enver Cesmeci, Halil Caliskan, Onuralp Kurt, Zafer Kuçukodaci, Atila Gungor
INTRODUCTION: Boric acid, which has antiseptic and acidic properties, is used to treat external and middle ear infections. However, we have not found any literature about the effect of boric acid powder on middle ear mucosa and inner ear. OBJECTIVE: The purpose of this study is to investigate possible ototoxic effects of boric acid powder (BAP) on cochlear outer hair cell function and histological changes in middle ear mucosa in a rat animal model. METHODS: Twenty healthy, mature Wistar albino rats were used in this study...
April 22, 2017: Brazilian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/28474437/clinical-efficacy-of-subgingivally-delivered-0-75-boric-acid-gel-as-an-adjunct-to-mechanotherapy-in-chronic-periodontitis-a-randomized-controlled-clinical-trial
#4
Dharmendra Kanoriya, Sandeep Singhal, Vibhuti Garg, Avani R Pradeep, Shruti Garg, Amit Kumar
AIM: Borinic acid quinoline esters are a recently-identified class of new antibacterial and anti-inflammatory compounds known to inhibit osteoclastic bone resorption. They have proposed to have osteostimulative properties by causing osteoblast differentiation in vivo and in vitro. The purpose of this double-masked, randomized, controlled clinical trial was to evaluate the effects of the subgingival delivery of boric acid gel as an adjunct to scaling and root planing (SRP) on clinical and radiographic parameters, and compare this method with SRP plus placebo gel alone in chronic periodontitis (CP) patients...
May 5, 2017: Journal of Investigative and Clinical Dentistry
https://www.readbyqxmd.com/read/28460310/synthesis-characterization-molecular-docking-and-in%C3%A2-vitro-antimalarial-properties-of-new-carboxamides-bearing-sulphonamide
#5
D I Ugwu, U C Okoro, P O Ukoha, S Okafor, A Ibezim, N M Kumar
Sulphonamides and carboxamides have shown large number of pharmacological properties against different types of diseases among which is malaria. Twenty four new carboxamide derivatives bearing benzenesulphonamoyl alkanamides were synthesized and investigated for their in silico and in vitro antimalarial and antioxidant properties. The substituted benzenesulphonyl chlorides (1a-c) were treated with various amino acids (2a-h) to obtain the benzenesulphonamoyl alkanamides (3a-x) which were subsequently treated with benzoyl chloride to obtain the N-benzoylated derivatives (5a-f, i-n and q-v)...
April 17, 2017: European Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/28451986/bt-proteins-have-no-detrimental-effects-on-larvae-of-the-green-lacewing-chrysopa-pallens-rambur-neuroptera-chrysopidae
#6
I Ali, S Zhang, M S Muhammad, M Iqbal, J-J J-J Cui
Biosafety of a genetically modified crop is required to be assessed prior to its commercialization. For this, a suitable artificial diet was developed and used to establish a dietary exposure test for assessing the toxicity of midgut-active Bt insecticidal proteins on Chrysopa pallens (Rambur). Subsequently, this dietary exposure test was used to evaluate the toxicity of the proteins Cry1Ab, Cry1Ac, Cry1Ah, Cry1Ca, Cry1F, Cry2Aa, Cry2Ab, and Vip3Aa on C. pallens larvae. Temporal stability, bioactivity, and the intake of the insecticidal proteins were confirmed by enzyme-linked immunosorbent assay and a sensitive-insect bioassay...
April 28, 2017: Neotropical Entomology
https://www.readbyqxmd.com/read/28443835/effect-of-boric-acid-versus-conventional-irrigation-solutions-on-the-bond-strength-between-fiber-post-and-root-dentin
#7
Ahmet Kursad Culhaoglu, Erdal Özcan, Mehmet Ali Kilicarslan, Emre Seker
PURPOSE: To compare the effect of boric acid solutions of different percentages to conventional irrigation solutions on the adhesive bond strength between fiber posts and radicular dentin surface with different cement types. MATERIALS AND METHODS: One hundred fifteen extracted human incisors were endodontically instrumented to a length of 14-15 mm, and 12-mm post spaces were prepared with specific drills. Cylindrical fiber posts (Panavia Post) were luted with two different composite cements (Panavia F 2...
April 25, 2017: Journal of Adhesive Dentistry
https://www.readbyqxmd.com/read/28441323/gold-nanoplates-for-a-localized-surface-plasmon-resonance-based-boric-acid-sensor
#8
Marlia Morsin, Muhamad Mat Salleh, Akrajas Ali Umar, Mohd Zainizan Sahdan
Localized surface plasmon resonance (LSPR) properties of metallic nanostructures, such as gold, are very sensitive to the dielectric environment of the material, which can simply be adjusted by changing its shape and size through modification of the synthesizing process. Thus, these unique properties are very promising, particularly for the detection of various types of chemicals, for example boric acid which is a non-permitted preservative employed in food preparations. For the sensing material, gold (Au) nanoplates with a variety of shapes, i...
April 25, 2017: Sensors
https://www.readbyqxmd.com/read/28429621/the-distribution-and-movement-of-american-cockroaches-in-urban-niches-of-new-orleans
#9
John C Carlson, Felicia A Rabito, Derek Werthmann, Mark Fox
American cockroaches are an important source of household allergens in tropical and semitropical climates. To determine which outdoor niches produce American cockroaches, traps were placed at 40 homes in New Orleans to collect nymphs. Nymphs were collected from the sewers, yards, and within the homes themselves. To compare sewers and yards as sources of cockroaches entering homes, adult cockroaches were collected, marked, and released into yards and sewers. No sewer-released cockroaches were collected in homes...
April 1, 2017: Clinical Pediatrics
https://www.readbyqxmd.com/read/28426679/control-of-zoonotic-cutaneous-leishmaniasis-vector-phlebotomus-papatasi-using-attractive-toxic-sugar-baits-atsb
#10
Abedin Saghafipour, Hassan Vatandoost, Ali Reza Zahraei-Ramazani, Mohammad Reza Yaghoobi-Ershadi, Yavar Rassi, Moharram Karami Jooshin, Mohammad Reza Shirzadi, Amir Ahmad Akhavan
INTRODUCTION: Attractive Toxic Sugar Baits (ATSB) is a new vector control method that meets Integrated Vector Management (IVM) goals. In an experimental design, this study aimed to determine effects of ATSB on control of Phlebotomus papatasi, as a main vector of Zoonotic Cutaneous Leishmaniasis (ZCL), in Qom Province, center of Iran. METHODS: In a cross-sectional design, boric acid was mixed with brown sugar solution and tested as toxic baits for P. papatasi. Two methods were utilized to use the baits: (a) spraying ATSB on vegetation, bushes, and shrubs; and (b) setting ATSB-treated barrier fences in front of colonies at 500 m distance from the houses in outskirts of villages...
2017: PloS One
https://www.readbyqxmd.com/read/28401221/synthesis-of-two-titanosilicates-with-distinct-interlayer-connections-from-similar-gels
#11
Peng Ji, Kun Lu, Xinqing Lu, Hao Xu, Peng Wu
Ti-SSZ-70 and Ti-ECNU-6, with identical intralayer structures but distinct interlayer connections, were prepared from similar synthetic gels free of alkali metal ions and boric acid. Ti-SSZ-70, composed of vertically misaligned MWW layers, was transferred to Ti-ECNU-6, structurally analogous to the Ti-MWW zeolite with a well-aligned layer stacking, upon the addition of an appropriate amount of hexamethyleneimine to the gel. These two titanosilicate catalysts exhibited outstanding catalytic activities in the liquid-phase alkene epoxidation...
May 9, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/28396085/electrophoretically-mediated-microanalysis-for-simultaneous-on-capillary-derivatization-of-standard-amino-acids-followed-by-micellar-electrokinetic-capillary-chromatography-with-laser-induced-fluorescence-detection
#12
Andrea Celá, Aleš Mádr, Zdeněk Glatz
Amino acids are crucial compounds involved in most biochemical processes essential for life. Since their dynamic turnover reflects the actual physiology of the cell/organism, a turnover assessment may provide valuable information related to multiple physiological and pathophysiological conditions. The sensitive determination of amino acids is predominantly associated with their derivatization which might be laborious, time-consuming and difficult to standardize. However, capillary electrophoresis offers the automatic injection and mixing of reactants, incubation of the reaction mixture, separation and detection of the reaction products in one on-capillary procedure...
March 31, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/28393528/one-step-transformation-of-coenzyme-a-into-analogues-by-transamidation
#13
Randy Sanichar, John C Vederas
Several coenzyme A (CoA) analogues are made in a single step under mild conditions via transamidation reactions catalyzed by boric acid in water. This approach offers rapid access to compounds useful for the study of a wide spectrum of enzyme catalyzed reactions, especially processes involving acyl carrier proteins (ACP) of polyketide synthases (PKS), fatty acid synthases (FAS), and nonribosomal peptide synthetases (NRPS). The CoA analogues presented are readily elaborated or extended by precedented reactions for specific applications that may be required...
April 10, 2017: Organic Letters
https://www.readbyqxmd.com/read/28391495/boric-acid-inhibition-of-trichophyton-rubrum-growth-and-conidia-formation
#14
Martin Schmidt
Trichophyton rubrum is a common human dermatophyte that is the causative agent of 80-93% of fungal infections of the skin and nails. While dermatophyte infections in healthy people are easily treatable with over-the-counter medications, such infections pose a higher risk for patients with compromised immune function and impaired regenerative potential. The efficacy of boric acid (BA) for the treatment of vaginal yeast infections prompted an investigation of the effect of BA on growth and morphology of T. rubrum...
April 8, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28387830/development-of-liquid-bait-with-unique-bait-station-for-control-of-dolichoderus-thoracicus-hymenoptera-formicidae
#15
Chung-Chi Lin, Tsai-Wei Chang, Hung-Wei Chen, Chung-Han Shih, Po-Cheng Hsu
The Dolichoderus thoracicus (Smith) has seriously infested urban, village, and agricultural environments in Taiwan. To develop optimal bait for the effective control of D. thoracicus, we investigated the feeding preferences of this ant at different sugar and amino acid concentrations in a laboratory setting. The number of feeding workers was significantly higher for 20% sucrose compared with that for other sugars at 10% and 20% concentrations. Furthermore, among all tested concentrations of monosodium glutamate (MSG; 1%, 3%, 5%, and 10%), the highest number of ants were attracted by 1% MSG with 20% sucrose...
April 6, 2017: Journal of Economic Entomology
https://www.readbyqxmd.com/read/28374970/human-bj-fibroblasts-is-an-alternative-to-mouse-balb-c-3t3-cells-in-in-vitro-neutral-red-uptake-assay
#16
Marika Mannerström, Tarja Toimela, Jertta-Riina Sarkanen, Tuula Heinonen
The OECD GD 129 BALB/c 3T3 Neutral Red Uptake (NRU) assay is a standardized test method for estimating starting dose for an acute oral systemic toxicity test in rodents. Mouse BALB/c 3T3 fibroblasts are the most commonly used cells in the NRU assay. We have previously transferred and validated BALB/c 3T3 NRU assay in our GLP laboratory. Subsequently, in order to obtain more human relevant cytotoxicity data, we performed an intra-laboratory validation using human BJ fibroblasts in the NRU assay instead of mouse BALB/c 3T3 fibroblasts...
April 4, 2017: Basic & Clinical Pharmacology & Toxicology
https://www.readbyqxmd.com/read/28373517/threonine-phosphorylation-regulates-polar-localization-of-the-boric-acid-transporter-nip5-1-in-root-cells
#17
EDITORIAL
Gregory Bertoni
No abstract text is available yet for this article.
April 2017: Plant Cell
https://www.readbyqxmd.com/read/28368904/preparation-and-anticancer-activity-evaluation-of-an-amorphous-drug-nanocomposite-by-simple-heat-treatment
#18
Honglei Zhan, Jun F Liang
The solubility of drug molecules is closely related to its bioactivity as it affects the dissolution rate and bioavailability, especially in the case of BCS IV drugs like camptothecin (CPT), a potential broad-spectrum anticancer agent. In this study, we construct a novel boric acid (BA)-coated CPT nanocomposite by means of a simple heat-treatment approach, which combines nanoscale size range and amorphous solid state together to improve the overall dissolution rate of CPT. This new CPT formulation showed a rod-like structure with nanoscale size and amorphous solid nature...
July 2017: Anti-cancer Drugs
https://www.readbyqxmd.com/read/28342883/kinetic-and-mechanistic-study-of-the-ph-dependent-activation-epoxidation-of-prodrug-treosulfan-including-the-reaction-inhibition-in-a-borate-buffer
#19
Michał Romański, Whitney Ratajczak, Franciszek Główka
A prodrug treosulfan (T) undergoes a pH-dependent activation to epoxide derivatives. The process seems to involve an intramolecular Williamson reaction (IWR) but clear kinetic evidence is lacking. Moreover, a cis-diol system present in the T structure is expected to promote complexation with boric acid. As a result, the prodrug epoxidation would be inhibited, however this phenomenon has not been investigated. In this paper, the effect of pH on the kinetics of T conversion to its monoepoxide was studied from a mechanistic point of view...
March 22, 2017: Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28341806/polar-localization-of-the-nip5-1-boric-acid-channel-is-maintained-by-endocytosis-and-facilitates-boron-transport-in-arabidopsis-roots
#20
Sheliang Wang, Akira Yoshinari, Tomoo Shimada, Ikuko Hara-Nishimura, Namiki Mitani-Ueno, Jian Feng Ma, Satoshi Naito, Junpei Takano
Boron uptake in Arabidopsis thaliana is mediated by nodulin 26-like intrinsic protein 5;1 (NIP5;1), a boric acid channel that is located preferentially on the soil side of the plasma membrane in root cells. However, the mechanism underlying this polar localization is poorly understood. Here, we show that the polar localization of NIP5;1 in epidermal and endodermal root cells is mediated by the phosphorylation of Thr residues in the conserved TPG (ThrProGly) repeat in the N-terminal region of NIP5;1. Although substitutions of Ala for three Thr residues in the TPG repeat did not affect lateral diffusion in the plasma membrane, these substitutions inhibited endocytosis and strongly compromised the polar localization of GFP-NIP5;1...
April 2017: Plant Cell
keyword
keyword
119412
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"