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Iliass Ennour Idrissi, Manal Rhezali, Abdellah Enourhbi, Taoufik Abou Elhassan, Hicham Nejmi
The use of peripheral nerve blocks has grown significantly in recent years not only because of the progress and availability of the materials necessary for its realization but also for enhancing patient safety. Anesthesia in the elderly or individuals with high anesthetic risk is always a challenge for the practitioner. Hence, the importance of peripheral nerve blocks in avoiding the side effects associated with general or spinal anesthesia. In this report, we present a case series of five patients with high anesthetic risk (classified American Society of Anesthesiologists (ASA) III or IV) who underwent different lower limb surgeries under a combined lumbar plexus-sciatic nerve block...
April 2024: Curēus
#22
Nguyen Xuan Khai, Truong Dinh Tien, Hoang Thi Dung, Nguyen Duc Thuan, Nguyen Huy Thong, Nguyen Tien Dung, Nguyen Viet Dung, Nguyen Viet Phuong, Ngo Tuan Minh
Pneumorrhachis (PR) is an uncommon condition characterized by the accumulation of air within the spinal canal. This finding may occur due to various causes, mostly after trauma and medical procedures. It can manifest with various features depending on the underlying cause, the location, and the extent of the air trapped. Clinically, the symptoms in affected patients can span a spectrum, ranging from being asymptomatic to manifesting as radiculopathies resulting from compression. The pneumorrhachis-related cauda equina syndrome is incredibly rare and typically appears as a large volume of air causing compression or irritation of the nerve roots in the lower spinal cord...
July 2024: Radiology Case Reports
#23
JOURNAL ARTICLE
(no author information available yet)
In order to promote the standardization of the treatment of neuropathic pain by spinal dorsal root entry surgery, alleviate the pain of certain specific neuropathic pain patients, and improve their quality of life and survival, experts with experience in neuropathic pain and spinal dorsal root entry surgery were organized by Functional Neurosurgery Group of the Neurosurgery Branch of the Chinese Medical Association and Functional Neurosurgery Expert Committee of Chinese Congress of Neurological Surgeons to write this consensus...
May 7, 2024: Zhonghua Yi Xue za Zhi [Chinese medical journal]
#24
JOURNAL ARTICLE
Takuya Yoshimoto, Mitsuhiro Nito, Wataru Hashizume, Kazuto Shimada, Tomomi Sato, Masaomi Shindo, Akira Naito
The anterior (DA) and posterior parts of the deltoid (DP) show alternating contraction during shoulder flexion and extension movements. It is expected that an inhibitory spinal reflex between the DA and DP exists. In this study, spinal reflexes between the DA and DP were examined in healthy human subjects using post-stimulus time histogram (PSTH) and electromyogram averaging (EMG-A). Electrical conditioning stimulation was delivered to the axillary nerve branch that innervates the DA (DA nerve) and DP (DP nerve) with the intensity below the motor threshold...
May 3, 2024: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
#25
JOURNAL ARTICLE
Kirsi Holopainen, Aleksi J Sihvonen, Jaakko Kauramäki, Teppo Särkämö, Anastasia Shulga
Paired associative stimulation (PAS) consisting of high-intensity transcranial magnetic stimulation (TMS) and high-frequency peripheral nerve stimulation (known as high-PAS) induces plastic changes and improves motor performance in patients with incomplete spinal cord injury (SCI). Listening to music during PAS may potentially improve mood and arousal and facilitate PAS-induced neuroplasticity via auditory-motor coupling, but the effects have not been explored. This pilot study aimed to determine if the effect of high-PAS on motor-evoked potentials (MEPs) and subjective alertness can be augmented with music...
May 3, 2024: Scientific Reports
#26
JOURNAL ARTICLE
Mickey E Abraham, Joel Martin, Joseph D Ciacci
Stem cell therapy has emerged as a promising area of scientific investigation, sparking considerable interest, especially in spinal cord injury (SCI). Sun et al.1 discover that the extracellular matrix (ECM) from the neonatal spinal cord transmits biochemical signals to endogenous axons, thus promoting axonal regeneration.
May 2, 2024: Cell Stem Cell
#27
REVIEW
Xinyu Zhang, Deshui Yu
RATIONALE: Guillain-Barré syndrome (GBS) epitomizes an acute peripheral neuropathy hallmarked by an autoimmune retort directed at the myelin sheath enwrapping peripheral nerves. While it is widely acknowledged that a majority of GBS patients boast a history of antecedent infections, the documentation of postoperative GBS occurrences is progressively mounting. Drawing upon an exhaustive compendium of recent case reports, the disease's inception spans a gamut from within 1 hour to 1...
May 3, 2024: Medicine (Baltimore)
#28
JOURNAL ARTICLE
Zhiyi Zhou, Shenjun Wang, Shujun Zhang, Xiang Pan, Haoxia Yang, Yin Zhuang, Zhengfeng Lu
BACKGROUND: Lumbar disc herniation was regarded as an age-related degenerative disease. Nevertheless, emerging reports highlight a discernible shift, illustrating the prevalence of these conditions among younger individuals. METHODS: This study introduces a novel deep learning methodology tailored for spinal canal segmentation and disease diagnosis, emphasizing image processing techniques that delve into essential image attributes such as gray levels, texture, and statistical structures to refine segmentation accuracy...
May 3, 2024: Medicine (Baltimore)
#29
Peri-operative management and analgesic strategy for a patient undergoing quadruple limb amputation.
L Fenton-May, M Irvine, D Huckle, P Carter
Inadequately managed amputation pain can contribute to postoperative morbidity and mortality. However, amputation pain can be challenging to manage due to its complex nature, with both central and peripheral nociceptive and neuropathic elements. Here, we present the case of a 47-year old man who developed irreversible ischaemic injuries to all four limbs following admission to intensive care with sepsis. He required quadruple amputation and we describe our approach to his peri-operative management including anaesthesia, invasive monitoring and the multi-modal approach to his peri-operative management using a combination of intravenous analgesics, bilateral brachial plexus nerve catheters and a combined spinal and epidural...
2024: Anaesthesia reports
#30
JOURNAL ARTICLE
Bushra M Alsayari, Shahad M Alshehri, Abdullatif Y Almulhim, Leena M Alzakry, Abdullatif A Alzuraiq, Fahad H Binshalhoub, Hanin M Banjer, Lama Mohammed A Alkhediwi, Kholood M Rasdwi, Abdul Sattar Khan
Background Low back pain (LBP) is a common musculoskeletal condition that affects individuals worldwide, causing difficulties in daily tasks and social interactions. It can be categorized based on chronicity, with acute, subacute, and chronic forms. The causes of backache vary among patients and can include inflammatory conditions, radiculopathy, pregnancy, trauma, osteoporosis, nerve root compression, cancer, plexopathy, infection, and other spinal diseases. Aim The aim is to investigate the association between COVID-19 infection and LBP between all Saudi adults and foreign adults who had positive COVID-19 tests in the eastern region of Saudi Arabia...
April 2024: Curēus
#31
JOURNAL ARTICLE
Longfei Shu, Qingchun Mu, Feihu Dai, Wei Zhao, Madiha Zahra Syeda, Yuhai Wang
OBJECTIVE: To summarize the clinical effect of a single-center retrospective analysis of the contralateral approach with a microscope and tubular retractor system for ipsilateral decompression in patients with lumbar lateral recess stenosis and a narrow spinal canal. METHODS: A total of 25 patients who underwent ipsilateral decompression surgery via a contralateral approach with microscope and tubular retractor system, performed by one surgeon at a single center were retrospectively examined...
2024: Frontiers in Neurology
#32
JOURNAL ARTICLE
Riccardo Antonio Ricciuti, Fabrizio Mancini, Giusy Guzzi, Daniele Marruzzo, Alessandro Dario, Alessandro Della Puppa, Alessandro Ricci, Andrea Barbanera, Andrea Talacchi, Andreas Schwarz, Antonino Germanò, Antonino Raco, Antonio Colamaria, Antonio Santoro, Riccardo Boccaletti, Carlo Conti, Carlo Conti, Nunzia Cenci, Christian Cossandi, Claudio Bernucci, Corrado Lucantoni, Giovanni Battista Costella, Diego Garbossa, Donato Carlo Zotta, Federico De Gonda, Felice Esposito, Flavio Giordano, Giancarlo D'Andrea, Gianluca Piatelli, Gianluigi Zona, Giannantonio Spena, Giovanni Tringali, Giuseppe Barbagallo, Carlo Giussani, Maurizio Gladi, Andrea Landi, Angelo Lavano, Letterio Morabito, Luciano Mastronardi, Marco Locatelli, Michele D'Agruma, Michele Maria Lanotte, Nicola Montano, Orazio Santo Santonocito, Angelo Pompucci, Raffaele de Falco, Franco Randi, Sara Bruscella, Ivana Sartori, Francesco Signorelli, Luigino Tosatto, Roberto Trignani, Vincenzo Esposito, Gualtiero Innocenzi, Sergio Paolini, Vincenzo Vitiello, Michele Alessandro Cavallo, Francesco Sala
INTRODUCTION: Intraoperative Neurophysiological Monitoring (IOM) is widely used in neurosurgery but specific guidelines are lacking. Therefore, we can assume differences in IOM application between Neurosurgical centers. RESEARCH QUESTION: The section of Functional Neurosurgery of the Italian Society of Neurosurgery realized a survey aiming to obtain general data on the current practice of IOM in Italy. MATERIALS AND METHODS: A 22-item questionnaire was designed focusing on: volume procedures, indications, awake surgery, experience, organization and equipe...
2024: Brain Spine
#33
REVIEW
Giusy Guzzi, Attilio Della Torre, Andrea Bruni, Angelo Lavano, Vincenzo Bosco, Eugenio Garofalo, Domenico La Torre, Federico Longhini
Chronic pain, a complex and debilitating condition, poses a significant challenge to both patients and healthcare providers worldwide. Conventional pharmacological interventions often prove inadequate in delivering satisfactory relief while carrying the risks of addiction and adverse reactions. In recent years, electric neuromodulation emerged as a promising alternative in chronic pain management. This method entails the precise administration of electrical stimulation to specific nerves or regions within the central nervous system to regulate pain signals...
May 2, 2024: J Anesth Analg Crit Care
#34
JOURNAL ARTICLE
Javier Muñoz Laguna, Astrid Kurmann, Léonie Hofstetter, Emanuela Nyantakyi, Lauren Clack, Heejung Bang, Nadine E Foster, Julia Braun, Milo A Puhan, Mazda Farshad, Cesar A Hincapié
INTRODUCTION: Blinding is a methodologically important aspect in randomised controlled trials yet frequently overlooked in trials of spinal manual therapy interventions for back pain. To help inform the blinding methods of a future, double-placebo-controlled trial comparing spinal manual therapy and nerve root injection for lumbosacral radicular pain, we set four objectives: (1) to assess the feasibility of blinding participants, randomly allocated to an active or placebo-control spinal manual therapy intervention protocol, (2) to assess the feasibility of blinding outcome assessors within the trial, (3) to explore the influence of spinal manual therapy experience and low back pain on blinding, and (4) to explore factors contributing to perceptions about intervention assignment among participants and outcome assessors...
May 2, 2024: Pilot and Feasibility Studies
#35
JOURNAL ARTICLE
George Georgoulis, Eleftherios Neromyliotis, Marc Sindou
BACKGROUND: Systematic descriptions of anatomical damage after brachial plexus injury (BPI) at the intradural level have been scarcely reported in detail. However, considering these damages, not only in the spinal nerve roots but also in the spinal cord itself, is crucial in determining the appropriate surgical approach to restore upper limb function and address refractory pain. Therefore, the authors present a descriptive study focusing on intradural findings observed during microsurgical DREZ-lesioning...
May 2, 2024: Acta Neurochirurgica
#36
REVIEW
Daniel Umansky, Kate Elzinga, Rajiv Midha
Advancement in microsurgical techniques and innovative approaches including greater use of nerve and tendon transfers have resulted in better peripheral nerve injury (PNI) surgical outcomes. Clinical evaluation of the patient and their injury factors along with a shift toward earlier time frame for intervention remain key. A better understanding of the pathophysiology and biology involved in PNI and specifically mononeuropathies along with advances in ultrasound and magnetic resonance imaging allow us, nowadays, to provide our patients with a logical and sophisticated approach...
2024: Handbook of Clinical Neurology
#37
REVIEW
Colin Chalk, Austin Zaloum
The femoral and obturator nerves both arise from the L2, L3, and L4 spinal nerve roots and descend into the pelvis before emerging in the lower limbs. The femoral nerve's primary function is knee extension and hip flexion, along with some sensory innervation to the leg. The obturator nerve's primary function is thigh adduction and sensory innervation to a small area of the medial thigh. Each may be injured by a variety of potential causes, many of them iatrogenic. Here, we review the anatomy of the femoral and obturator nerves and the clinical features and potential etiologies of femoral and obturator neuropathies...
2024: Handbook of Clinical Neurology
#38
JOURNAL ARTICLE
Fei San Lee, Uyen N Nguyen, Eliza J Munns, Rebecca A Wachs
Low back pain, knee osteoarthritis, and cancer patients suffer from chronic pain. Aberrant nerve growth into intervertebral disc, knee, and tumors, are common pathologies that lead to these chronic pain conditions. Axonal dieback induced by capsaicin (Caps) denervation has been FDA-approved to treat painful neuropathies and knee osteoarthritis but with short-term efficacy and discomfort. Herein, we propose to evaluate pyridoxine (Pyr), vincristine sulfate (Vcr) and ionomycin (Imy) as axonal dieback compounds for denervation with potential to alleviate pain...
2024: PloS One
#39
REVIEW
Siôn Owain Roberts, Arun Cardozo
The spinal accessory nerve, considered part of the eleventh cranial nerve, provides motor innervation to sternocleidomastoid and trapezius. A comprehensive literature review and two cadaveric dissections were undertaken. The spinal accessory nerve originates from the spinal accessory nucleus. Its rootlets unite and ascend between the denticulate ligament and dorsal spinal rootlets. Thereafter, it can anastomose with spinal roots, such as the McKenzie branch, and/or cranial roots. The spinal accessory nerve courses intracranially via foramen magnum and exits via jugular foramen, within which it usually lies anteriorly...
May 2, 2024: Anatomical Science International
#40
JOURNAL ARTICLE
Silvia Olivi, Paola Paglierani, Elisa Maietti, Paola Rucci, Gaia Musumeci, Carlotte Kiekens, Jacopo Visani, Carlo Sacco
OBJECTIVE: To describe the 2-year functional outcomes of nerve transfer (NT) for upper extremity reanimation. STUDY DESIGN: A prospective case series. SETTING: A highly specialized rehabilitation hospital for spinal cord injury (SCI) in Italy. INTERVENTION: Upper limb nerve transfer (32 NTs, 15 upper limbs). PARTICIPANTS: Twelve male individuals with traumatic SCI (AIS A or B, neurological level from C4 to C7) were enrolled; 24-month follow-up data were available for 11...
May 2, 2024: Journal of Spinal Cord Medicine
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