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https://www.readbyqxmd.com/read/27891027/purely-extradural-spinal-nerve-root-hemangioblastomas
#1
REVIEW
Murat Hamit Aytar, Ulaş Yener, Murat Şakir Ekşi, Behram Kaya, Serdar Özgen, Aydin Sav, Ahmet Alanay
Spinal nerve root hemangioblastomas present mostly as intradural-extradurally. Purely extradural spinal nerve root hemangioblastoma is a very rare entity. In this study, we aimed to analyze epidemiological perspectives of purely extradural spinal nerve root hemangioblastomas presented in English medical literature in addition to our own exemplary case. PubMed/MEDLINE was searched using the terms "hemangioblastoma," "extradural," "spinal," and "nerve root." Demographical variables of age, gender, concomitant presence of von Hippel-Lindau (VHL) disease; spinal imaging and/or intraoperative findings for tumor location were surveyed from retrieved articles...
October 2016: Journal of Craniovertebral Junction and Spine
https://www.readbyqxmd.com/read/27879489/breast-fibroadenoma-with-increased-activity-on-68ga-dotatate-pet-ct
#2
Georgios Z Papadakis, Corina Millo, Samira M Sadowski, Apostolos H Karantanas, Ulas Bagci, Nicholas J Patronas
Fibroadenoma is the most common benign breast tumor in women of reproductive age, carrying little to no risk of breast cancer development. We report on a case of a woman with history of neuroendocrine tumor who on follow-up imaging tests underwent whole-body PET/CT study using Ga DOTATATE. The scan showed increased focal activity in the right breast, which was biopsied revealing a fibroadenoma. The presented data suggests cell surface overexpression of somatostatin receptors by this benign breast tumor. Moreover, this finding emphasizes the need for cautious interpretation of Ga DOTATATE-avid breast lesions that could mimic malignancy in neuroendocrine tumor patients...
November 22, 2016: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/27867699/characterization-of-autism-spectrum-disorder-with-spontaneous-hemodynamic-activity
#3
Jun Li, Lina Qiu, Lingyu Xu, Ernest V Pedapati, Craig A Erickson, Ulas Sunar
Functional near-infrared spectroscopy (fNIRS) was used to investigate spontaneous hemodynamic activity in the temporal cortex for typically developing (TD) children and children with autism spectrum disorder (ASD). Forty-seven children participated in the experiments including twenty-five with ASD. Compared with TD children, children with ASD showed weaker bilateral resting-state functional connectivity (RSFC), but much stronger fluctuation magnitude in terms of oxy-hemoglobin (HbO2) and deoxy-hemoglobin (Hb)...
October 1, 2016: Biomedical Optics Express
https://www.readbyqxmd.com/read/27852639/improving-geriatric-prescribing-in-the-ed-a-qualitative-study-of-facilitators-and-barriers-to-clinical-decision-support-tool-use
#4
Ann E Vandenberg, Camille P Vaughan, Melissa Stevens, Susan N Hastings, James Powers, Alayne Markland, Ula Hwang, William Hung, Katharina V Echt
QUALITY PROBLEM OR ISSUE: Clinical decision support (CDS) may improve prescribing for older adults in the Emergency Department (ED) if adopted by providers. INITIAL ASSESSMENT: Existing prescribing order entry processes were mapped at an initial Veterans Administration Medical Center site, demonstrating cognitive burden, effort and safety concerns. CHOICE OF SOLUTION: Geriatric order sets incorporating 2012 Beers guidelines and including geriatric prescribing advice and prepopulated order options were developed...
November 16, 2016: International Journal for Quality in Health Care
https://www.readbyqxmd.com/read/27851915/epigenomic-profiling-of-human-cd4-t-cells-supports-a-linear-differentiation-model-and-highlights-molecular-regulators-of-memory-development
#5
Pawel Durek, Karl Nordström, Gilles Gasparoni, Abdulrahman Salhab, Christopher Kressler, Melanie de Almeida, Kevin Bassler, Thomas Ulas, Florian Schmidt, Jieyi Xiong, Petar Glažar, Filippos Klironomos, Anupam Sinha, Sarah Kinkley, Xinyi Yang, Laura Arrigoni, Azim Dehghani Amirabad, Fatemeh Behjati Ardakani, Lars Feuerbach, Oliver Gorka, Peter Ebert, Fabian Müller, Na Li, Stefan Frischbutter, Stephan Schlickeiser, Carla Cendon, Sebastian Fröhler, Bärbel Felder, Nina Gasparoni, Charles D Imbusch, Barbara Hutter, Gideon Zipprich, Yvonne Tauchmann, Simon Reinke, Georgi Wassilew, Ute Hoffmann, Andreas S Richter, Lina Sieverling, Hyun-Dong Chang, Uta Syrbe, Ulrich Kalus, Jürgen Eils, Benedikt Brors, Thomas Manke, Jürgen Ruland, Thomas Lengauer, Nikolaus Rajewsky, Wei Chen, Jun Dong, Birgit Sawitzki, Ho-Ryun Chung, Philip Rosenstiel, Marcel H Schulz, Joachim L Schultze, Andreas Radbruch, Jörn Walter, Alf Hamann, Julia K Polansky
The impact of epigenetics on the differentiation of memory T (Tmem) cells is poorly defined. We generated deep epigenomes comprising genome-wide profiles of DNA methylation, histone modifications, DNA accessibility, and coding and non-coding RNA expression in naive, central-, effector-, and terminally differentiated CD45RA(+) CD4(+) Tmem cells from blood and CD69(+) Tmem cells from bone marrow (BM-Tmem). We observed a progressive and proliferation-associated global loss of DNA methylation in heterochromatic parts of the genome during Tmem cell differentiation...
November 15, 2016: Immunity
https://www.readbyqxmd.com/read/27847382/there-is-a-positive-correlation-between-socioeconomic-status-and-ovarian-reserve-in-women-of-reproductive-age
#6
Mert Ulas Barut, Elif Agacayak, Murat Bozkurt, Tarık Aksu, Talip Gul
BACKGROUND The purpose of this study was to investigate the potential association between socioeconomic status and ovarian reserve, anti-Mullerian hormone level, antral follicle count, and follicle stimulating hormone level in women of reproductive age. MATERIAL AND METHODS A total of 101 married women between 20-35 years of age who presented to the Department of Obstetrics and Gynecology, Health Research System In Vitro Fertilization (HRS IVF) Center between October 2014 and November 2015 and met the inclusion criteria were included in this study...
November 16, 2016: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/27843357/proximal-femoral-fracture-surgery-in-a-patient-with-osteopetrosis-tarda-complications-and-treatment-strategy
#7
Fırat Seyfettinoglu, Ümit Tuhanioğlu, Hasan Ulas Ogur, Hakan Cicek
Osteopetrosis is a rare, inherited disease characterized by defects in osteoclastic function that results in defective bone resorption. When fractures are encountered, fixation is extremely difficult. Osteopetrosis patients have an increased predisposition to infection. If infection develops after a fracture, treatment is more difficult. In this paper, treatment is presented of a 49-year old female to whom proximal femoral nailing was applied for fixation of an osteopetrotic proximal femur fracture; and when it was unsuccessful, revision was made with a locked anatomic plate, which subsequently led to development of infection...
2016: International Medical Case Reports Journal
https://www.readbyqxmd.com/read/27834658/single-channel-sparse-nonnegative-blind-source-separation-method-for-automatic-3d-delineation-of-lung-tumor-in-pet-images
#8
Ivica Kopriva, Wei Ju, Bin Zhang, Fei Shi, Dehui Xiang, Kai Yu, Ximing Wang, Ulas Bagci, Xinjian Chen
In this paper, we propose a novel method for single-channel blind separation of non-overlapped sources and, to the best of our knowledge, apply it for the first time to automatic segmentation of lung tumors in Positron Emission Tomography (PET) images. Our approach first converts 3D PET image into a pseudo multichannel image. Afterwards, regularization free sparseness constrained nonnegative matrix factorization is used to separate tumor from other tissues. By using complexity based criterion, we select tumor component as the one with minimal complexity...
November 3, 2016: IEEE Journal of Biomedical and Health Informatics
https://www.readbyqxmd.com/read/27830640/anxiety-depression-suicidal-ideation-and-stressful-life-events-in-non-cardiac-adolescent-chest-pain-a-comparative-study-about-the-hidden-part-of-the-iceberg
#9
Kayi Eliacik, Ali Kanik, Nurullah Bolat, Hilal Mertek, Baris Guven, Ulas Karadas, Buket Dogrusoz, Ali Rahmi Bakiler
Chest pain in adolescents is rarely associated with cardiac disease. Adolescents with medically unexplained chest pain usually have high levels of anxiety and depression. Psychological stress may trigger non-cardiac chest pain. This study evaluated risk factors that particularly characterise adolescence, such as major stressful events, in a clinical population. The present study was conducted on 100 adolescents with non-cardiac chest pain and 76 control subjects. Stressful life events were assessed by interviewing patients using a 36-item checklist, along with the Children's Depression Inventory and Spielberger's State-Trait Anxiety Inventory for children, in both groups...
November 10, 2016: Cardiology in the Young
https://www.readbyqxmd.com/read/27821651/can-the-myocardial-performance-index-be-used-as-a-new-predictive-factor-for-a-poor-prognosis-in-fetuses-with-idiopathic-polyhydramnios
#10
Cenk Gezer, Atalay Ekin, Mehmet Ozeren, Cuneyt Eftal Taner, Emre Mat, Ulas Solmaz
OBJECTIVES: The purpose of this study was to determine whether there are any changes in cardiac function in fetuses with idiopathic polyhydramnios and also to evaluate the value of the myocardial performance index for prediction of adverse perinatal outcomes. METHODS: A prospective case-control study was conducted with a total of 134 fetuses between 24 and 40 weeks' gestation. Polyhydramnios was defined as an amniotic fluid index of greater than 24 cm. Seventy-three fetuses of healthy mothers were assigned as the control group whereas 36 fetuses with an amniotic fluid index of 24 to 34 cm constituted the nonsevere polyhydramnios group, and 31 fetuses with an amniotic fluid index of 35 cm or greater constituted the severe polyhydramnios group...
December 2016: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/27805530/venoarterial-extracorporeal-membrane-oxygenation-support-as-a-bridge-to-heart-transplant-report-of-3-cases
#11
Ender Gedik, Aydın Ulaş, Özgür Ersoy, Funda Atar, Aynur Camkıran Fırat, Arash Pirat
Heart transplant is the only definitive treatment of end-stage heart failure. Venoarterial extracorporeal membrane oxygenation may be used as a bridge to heart transplant. Among 31 patients who underwent heart transplant between January 2014 and June 2016, we present our experiences with 3 patients who received venoarterial extracorporeal support as a bridge to heart transplant. The first patient was a 51-year-old male with ischemic dilated cardiomyopathy. Transplant was performed after 6 days of extracorporeal support, and the patient was discharged and alive at follow-up...
November 2016: Experimental and Clinical Transplantation
https://www.readbyqxmd.com/read/27798177/synaptic-contributions-to-receptive-field-structure-and-response-properties-in-the-rodent-lateral-geniculate-nucleus-of-the-thalamus
#12
Vandana Suresh, Ulaş M Çiftçioğlu, Xin Wang, Brittany M Lala, Kimberly R Ding, William A Smith, Friedrich T Sommer, Judith A Hirsch
: Comparative physiological and anatomical studies have greatly advanced our understanding of sensory systems. Many lines of evidence show that the murine lateral geniculate nucleus (LGN) has unique attributes, compared with other species such as cat and monkey. For example, in rodent, thalamic receptive field structure is markedly diverse, and many cells are sensitive to stimulus orientation and direction. To explore shared and different strategies of synaptic integration across species, we made whole-cell recordings in vivo from the murine LGN during the presentation of visual stimuli, analyzed the results with different computational approaches, and compared our findings with those from cat...
October 26, 2016: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/27797638/preparing-older-adults-with-serious-illness-to-formulate-their-goals-for-medical-care-in-the-emergency-department
#13
Kei Ouchi, Vinicius Knabben, Laura Rivera-Reyes, Niharika Ganta, Laura P Gelfman, Rebecca Sudore, Ula Hwang
BACKGROUND: Emergency department (ED) clinicians often lack training and resources to conduct advance care planning (ACP) conversations. The use of technology for health education is increasing, yet little is known if it can be used to engage older ED patients in ACP. OBJECTIVE: To determine the feasibility of using tablets to provide ACP education ( www.prepareforyourcare.org )(PREPARE) to older ED patients. DESIGN: A feasibility study conducted in late 2014 and early 2015...
October 31, 2016: Journal of Palliative Medicine
https://www.readbyqxmd.com/read/27792326/a-rieske-type-oxygenase-of-pseudomonas-sp-biomig1-converts-benzalkonium-chlorides-to-benzyldimethyl-amine
#14
Emine Ertekin, Konstantinos T Konstantinidis, Ulas Tezel
Recently, an array of eight genes involved in the biotransformation of benzalkonium chlorides (BACs) - an active ingredient of many disinfectants - to benzyldimethyl amine (BDMA) was identified in the genome of Pseudomonas sp. BIOMIG1, which is a bacterium present in various environments and mineralizes BACs. In this study, we showed that heterologous expression of an oxygenase gene (oxyBAC) present in this gene array in E. coli resulted in formation of BDMA from BACs at a rate of 14 µM h-1. oxyBAC is phylogenetically classified as a Rieske-type oxygenase (RO) and belongs to a group which catalyzes the cleavage of C-N+ bond between either methyl or alkyl ester and a quaternary nitrogen (N) of natural QACs such as stachydrine, carnitine and trimethylglycine...
October 28, 2016: Environmental Science & Technology
https://www.readbyqxmd.com/read/27787895/regional-nerve-blocks-improve-pain-and-functional-outcomes-in-hip-fracture-a-randomized-controlled-trial
#15
R Sean Morrison, Eitan Dickman, Ula Hwang, Saadia Akhtar, Taja Ferguson, Jennifer Huang, Christina L Jeng, Bret P Nelson, Meg A Rosenblatt, Jeffrey H Silverstein, Reuben J Strayer, Toni M Torrillo, Knox H Todd
OBJECTIVES: To compared outcomes of regional nerve blocks with those of standard analgesics after hip fracture. DESIGN: Multisite randomized controlled trial from April 2009 to March 2013. SETTING: Three New York hospitals. PARTICIPANTS: Individuals with hip fracture (N = 161). INTERVENTION: Participants were randomized to receive an ultrasound-guided, single-injection, femoral nerve block administered by emergency physicians at emergency department (ED) admission followed by placement of a continuous fascia iliaca block by anesthesiologists within 24 hours (n = 79) or conventional analgesics (n = 82)...
October 27, 2016: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/27780164/assessment-of-palliative-care-in-lung-cancer-in-turkey
#16
Yılmaz Bülbül, Tevfik Ozlu, Sibel Arinc, Berna Akinci Ozyurek, Hulya Gunbatar, Aysegul Senturk, Ayse Bahadir, Melike Ozcelik, Ufuk Yilmaz, Makbule Ozlem Akbay, Leyla Saglam, Talat Kilic, Gamze Kirkil, Neslihan Ozcelik, Dursun Tatar, Serap Argun Baris, Durdu Mehmet Yavsan, Hadice Selimoglu Sen, Serdar Berk, Murat Acat, Gulfidan Cakmak, Perran Fulden Yumuk, Yavuz Selim Intepe, Ümran Toru, Sibel Oktem Ayik, Ilknur Basyigit, Sibel Ozkurt, Levent Cem Mutlu, Zehra Asuk Yasar, Hidir Esme, Mehmet Muharrem Erol, Ozlem Oruc, Yurdanur Erdoğan, Selvi Asker, Arife Ulas, Serhat Erol, Bugra Kerget, Ahmet Emin Erbaycu, Turgut Teke, Mehmet Beşiroğlu, Huseyin Can, Ayse Dalli, Fahrettin Talay
No abstract text is available yet for this article.
October 24, 2016: Medical Principles and Practice: International Journal of the Kuwait University, Health Science Centre
https://www.readbyqxmd.com/read/27774985/thousands-of-microbial-genomes-shed-light-on-interconnected-biogeochemical-processes-in-an-aquifer-system
#17
Karthik Anantharaman, Christopher T Brown, Laura A Hug, Itai Sharon, Cindy J Castelle, Alexander J Probst, Brian C Thomas, Andrea Singh, Michael J Wilkins, Ulas Karaoz, Eoin L Brodie, Kenneth H Williams, Susan S Hubbard, Jillian F Banfield
The subterranean world hosts up to one-fifth of all biomass, including microbial communities that drive transformations central to Earth's biogeochemical cycles. However, little is known about how complex microbial communities in such environments are structured, and how inter-organism interactions shape ecosystem function. Here we apply terabase-scale cultivation-independent metagenomics to aquifer sediments and groundwater, and reconstruct 2,540 draft-quality, near-complete and complete strain-resolved genomes that represent the majority of known bacterial phyla as well as 47 newly discovered phylum-level lineages...
October 24, 2016: Nature Communications
https://www.readbyqxmd.com/read/27774968/-ultrasound-assisted-catheter-directed-thrombolysis-of-acute-pulmonary-embolism-via-the-subclavian-vein-alternative-access-path
#18
Veysel Özgür Barış, Evren Özçınar, Özgür Ulaş Özcan, Mustafa Şırlak
Routinely, the femoral vein is used for access in ultrasound-assisted, catheter-directed thrombolysis (USAT). Presently described is a case of bilateral femoral venous occlusion caused by chronic thrombosis, successfully treated with USAT, using subclavian vein for access.
October 2016: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
https://www.readbyqxmd.com/read/27774714/synthesis-of-mesoporous-lithium-titanate-thin-films-and-monoliths-as-an-anode-material-for-high-rate-lithium-ion-batteries
#19
Ömer Dag, Fadime Mert Balcı, Ömer Ulaş Kudu, Eda Yilmaz
Mesoporous Li4Ti5O12 (LTO) thin film is an important anode material for lithium-ion batteries (LIBs). Mesoporous films could be prepared by self-assembly processes. Here we employed a molten salt assisted self-assembly (MASA) process to prepare mesoporous thin films of LTOs. A clear ethanol solution of CTAB, P123, LiNO3, HNO3, and Ti(OC4H9)4 form a gel-like meso-ordered films upon either by spin or spray coating. In the assembly process, The CTAB/P123 mole ratio of 14 is required to accommodate enough salt species in the mesophase, where the Li(I)/P123 can be varied between a mole ratio of 28 and 72...
October 23, 2016: Chemistry: a European Journal
https://www.readbyqxmd.com/read/27773986/implementing-the-equipped-medication-management-program-at-5-va-emergency-departments
#20
Ann E Vandenberg, Melissa Stevens, Katharina V Echt, S Nicole Hastings, James Powers, Alayne Markland, Ula Hwang, William Hung, Stephanie Belbis, Camille P Vaughan
The Enhancing Quality of Prescribing Practices for Older Veterans Discharged From the Emergency Department (EQUiPPED) program aimed to reduce potentially inappropriate medication prescribing to older adults at 5 VAMCs.
April 2016: Federal Practitioner: for the Health Care Professionals of the VA, DoD, and PHS
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