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https://www.readbyqxmd.com/read/28910830/consensus-guidelines-for-therapeutic-drug-monitoring-in-neuropsychopharmacology-update-2017
#1
C Hiemke, N Bergemann, H W Clement, A Conca, J Deckert, K Domschke, G Eckermann, K Egberts, M Gerlach, C Greiner, G Gründer, E Haen, U Havemann-Reinecke, G Hefner, R Helmer, G Janssen, E Jaquenoud, G Laux, T Messer, R Mössner, M J Müller, M Paulzen, B Pfuhlmann, P Riederer, A Saria, B Schoppek, G Schoretsanitis, M Schwarz, M Silva Gracia, B Stegmann, W Steimer, J C Stingl, M Uhr, S Ulrich, S Unterecker, R Waschgler, G Zernig, G Zurek, P Baumann
Therapeutic drug monitoring (TDM) is the quantification and interpretation of drug concentrations in blood to optimize pharmacotherapy. It considers the interindividual variability of pharmacokinetics and thus enables personalized pharmacotherapy. In psychiatry and neurology, patient populations that may particularly benefit from TDM are children and adolescents, pregnant women, elderly patients, individuals with intellectual disabilities, patients with substance abuse disorders, forensic psychiatric patients or patients with known or suspected pharmacokinetic abnormalities...
September 14, 2017: Pharmacopsychiatry
https://www.readbyqxmd.com/read/28910213/the-challenge-of-transforming-the-diagnostic-system-of-personality-disorders
#2
Sabine C Herpertz, Steven K Huprich, Martin Bohus, Andrew Chanen, Marianne Goodman, Lars Mehlum, Paul Moran, Giles Newton-Howes, Lori Scott, Carla Sharp
While the DSM-5 alternative model of personality disorder (PD) diagnosis allows the field to systematically compare categorical and dimensional classifications, the ICD-11 proposal suggests a radical change by restricting the classification of PDs to one category, deleting all specific types, basing clinical service provision exclusively upon a severity dimension, and restricting trait domains to secondary qualifiers without defining cutoff points. This article reflects broad international agreement about the state of PD diagnosis...
September 14, 2017: Journal of Personality Disorders
https://www.readbyqxmd.com/read/28898309/-psychiatric-complications-of-cannabis-use
#3
Adriana V Bulacia
atural and synthetic cannabinoids modify the modulatory activity of the endocannabinoid system. Psychiatric complications induced by cannabis are analyzed, i.e. those that start with intoxication but persist beyond the removal of the drug (cognitive, psychotic and anxiety disorders) and the development of addictive behavior. Adolescence is the period of greatest vulnerability to cognitive impact. Cannabis-induced psychosis has been linked to consumption of high concentration of tetrahydrocannabinol and personality traits of anxiety and somatization...
November 2016: Vertex: Revista Argentina de Psiquiatriá
https://www.readbyqxmd.com/read/28894999/needs-of-adolescents-and-young-adults-with-neurodevelopmental-disorders-comparisons-of-young-people-and-parent-perspectives
#4
Hanna Eklund, James Findon, Tim Cadman, Hannah Hayward, Declan Murphy, Philip Asherson, Karen Glaser, Kiriakos Xenitidis
This study used the Camberwell Assessment of Need for adults with Developmental and Intellectual Disabilities (CANDID) to examine the social, physical health and mental health needs of 168 young people (aged 14-24 years) with neurodevelopmental disorders and compared young person and parent ratings of need. Agreement was poor in 21 out of 25 domains. Parents consistently reported higher levels of need than young people in the majority of domains although young people with ADHD reported significantly more needs in physical health, eyesight/hearing, seizures, other mental health problems and safety of others than their parents...
September 11, 2017: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/28886575/changing-social-norms-the-impact-of-normative-feedback-included-in-motivational-enhancement-therapy-on-cannabis-outcomes-among-heavy-using-adolescents
#5
Claire E Blevins, Denise D Walker, Robert S Stephens, Kelsey E Banes, Roger A Roffman
INTRODUCTION: Heavy cannabis use is a problematic behavior, particularly among some adolescents. Adolescents are particularly prone to social influence. As such, injunctive norms (perceptions of others' approval of cannabis use) and descriptive norms (perception of frequency of others' cannabis use) influence cannabis behavior. Given that norms are not always accurate, motivational enhancement therapy aims to reduce cannabis use through normative feedback and correction of normative misconceptions...
September 1, 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/28884738/-the-influence-of-physical-loads-on-the-functional-parameters-of-the-eyes-in-the-children-and-adolescents-regularly-engaged-in-sports-activities
#6
O V Yurova, D V Andjelova, A A Chayka
Myopia (short-sightedness) is the most common refractive disorder throughout the world prone to progression which is caused, inter alia, by violation of the working regime and resting conditions in the combination with the enhanced physical and psychological stresses. AIM: The objective of the present study was to evaluate the influence of the strenuous physical exercises on the visual analyzer in the children and adolescents regularly engaged in sports activities. MATERIAL AND METHODS: A total of 600 children and adolescents at the age from 8 to 17 years were recruited for the participation in the study...
2017: Voprosy Kurortologii, Fizioterapii, i Lechebnoĭ Fizicheskoĭ Kultury
https://www.readbyqxmd.com/read/28884246/impulsivity-dimensions-and-risky-sex-behaviors-in-an-at-risk-young-adult-sample
#7
Inga Curry, Jeremy W Luk, Ryan S Trim, Christian J Hopfer, John K Hewitt, Michael C Stallings, Sandra A Brown, Tamara L Wall
Impulsivity is a personality-based risk factor that has been well studied in relation to risky sexual behavior. Recent conceptualizations of impulsivity have proposed multidimensional facets comprised of premeditation, perseverance, sensation seeking, negative urgency, and positive urgency (UPPS-P model). Prior studies have found that these facets are associated with risky sexual behavior in adolescent and college student samples, but no prior studies have evaluated them in clinical samples. The current study examined how impulsivity-related traits related to two different risky sexual behaviors in a clinical sample of at-risk young adults who had both conduct disorder and substance use disorder symptoms as adolescents (n = 529)...
September 7, 2017: Archives of Sexual Behavior
https://www.readbyqxmd.com/read/28881362/-sensory-inventory-si-self-assessment-of-sensory-sensitivity-for-adults-and-adolescents
#8
Vera Zamoscik, Christine Niemeyer, Martin Fungisai Gerchen, Sabrina Christina Fenske, Michael Witthöft, Peter Kirsch
An adequate perception of the environment is one of the main foundations of adaptive behavior. Furthermore, sensory sensitivity varies from person to person and can play a central role in the development and course of mental disorders. The objective was the development of a questionnaire for the multidimensional assessment of sensory sensitivity. A total of 1417 persons were evaluated with the Sensory Inventory (SI). The factorial validity was tested with exploratory factor analyses and exploratory structural equation modeling...
September 2017: Fortschritte der Neurologie-Psychiatrie
https://www.readbyqxmd.com/read/28866247/using-personal-construct-methodology-to-explore-relationships-with-adolescents-with-autism-spectrum-disorder
#9
Mark Murphy, Jan Burns, Elizabeth Kilbey
BACKGROUND: Research shows that adolescents with Autism Spectrum Disorder (ASD) experience difficulties developing friendships, and that loneliness is a significant factor contributing to higher incidence of anxiety and depression within this population. AIMS: This study aimed to provide an in-depth analysis of relationships as described by adolescents with ASD, and, from these descriptions, to explore what can be inferred about the development of successful interpersonal relationships for these individuals...
August 31, 2017: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/28843630/moral-disengagement-and-callous-unemotional-traits-configurations-in-adolescents-with-disruptive-behavior-disorder-a-person-oriented-approach
#10
Marinella Paciello, Gabriele Masi, Maria Grazie Clemente, Annarita Milone, Pietro Muratori
The interplay between Callous Unemotional Traits (CU) and Moral Disengagement (MD) was examined in a sample of 90 adolescents with Disruptive Behavior Disorders. Using a person-centered approach, three CU and MD configurations were identified, attesting the strong relationship between these two moral dimensions. However, for some adolescents, CU and MD do not 'move together'. Practical implications are discussed in terms of assessment and intervention.
August 19, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28841475/reflective-function-mediates-the-relationship-between-emotional-maltreatment-and-borderline-pathology-in-adolescents-a-preliminary-investigation
#11
Jeremy Quek, Louise K Newman, Clair Bennett, Michael S Gordon, Naysun Saeedi, Glenn A Melvin
Deficits in mentalizing, particularly within the context of attachment relationships i.e., reflective function (RF), are posited to result from childhood maltreatment and to influence the development of borderline personality disorder (BPD). Whilst a mentalization-based model of BPD provides a theoretical explanation, direct empirical support for this model, in linking childhood maltreatment to borderline pathology remains limited. This study examined the interrrelationships between childhood maltreatment, RF, and borderline pathology in a mixed adolescent sample, consisting of adolescents with BPD (n=26) and a group of non-clinical adolescents (n=25)...
August 22, 2017: Child Abuse & Neglect
https://www.readbyqxmd.com/read/28837938/the-relations-between-inadequate-parent-child-boundaries-and-borderline-personality-disorder-in-adolescence
#12
Salome Vanwoerden, Allison Kalpakci, Carla Sharp
Borderline Personality Disorder (BPD) is a severe mental illness that onsets in adolescence. Research has demonstrated the central role of parent-child relationships for the development and maintenance of BPD although more research is necessary to clarify the specific dynamics that relate to BPD during adolescence. Based on preliminary research establishing the importance of parent-child boundaries for adolescent BPD, this study sought to evaluate the relations between different forms of inadequate boundaries and BPD in adolescence using a multi-method approach...
August 12, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28831672/update-on-mental-health-of-infants-and-children-of-parents-affected-with-mental-health-issues
#13
REVIEW
Gisèle Apter, Anne Bobin, Marie-Camille Genet, Maya Gratier, Emmanuel Devouche
This paper highlights the most recent publications, in the field of psychiatry, on offspring of patients with psychiatric illnesses such as schizophrenia and bipolar disorder, and then summarizes what we know about the progeny of adults with mood disorders, the most prevalent of parental disorders. Studies examining personality disorders and contextual factors such as stress and trauma are examined with a focus on the crucial question of development and attachment status in children. Findings converge to reveal that offspring of parents (generally mothers) with most major psychiatric disorders present a higher risk for all mental disorders, and a wide range of disorders are also found in children, adolescent, and finally adult offspring of mothers with mood and anxiety disorders...
August 23, 2017: Current Psychiatry Reports
https://www.readbyqxmd.com/read/28829775/novel-subgroups-of-attention-deficit-hyperactivity-disorder-identified-by-topological-data-analysis-and-their-functional-network-modular-organizations
#14
Sunghyon Kyeong, Jae-Jin Kim, Eunjoo Kim
Attention-deficit/hyperactivity disorder (ADHD) is a clinically heterogeneous condition and identification of clinically meaningful subgroups would open up a new window for personalized medicine. Thus, we aimed to identify new clinical phenotypes in children and adolescents with ADHD and to investigate whether neuroimaging findings validate the identified phenotypes. Neuroimaging and clinical data from 67 children with ADHD and 62 typically developing controls (TDCs) from the ADHD-200 database were selected...
2017: PloS One
https://www.readbyqxmd.com/read/28826267/inpatient-psychiatric-treatment-is-not-always-effective-in-adolescent-sample
#15
Barbara Remberk, Anna Katarzyna Bażyńska, Joanna Brągoszewska, Piotr Niwiński, Agnieszka Piróg-Balcerzak, Lidia Popek, Filip Rybakowski
OBJECTIVE: Numerous studies confirm efficacy of psychiatric treatment as well as psychiatric placebo. The aim of the current study was the assessment of improvement rate and factors associated with treatment response in naturalistic group of adolescent inpatients. METHODS: Eighty two consecutive adolescent inpatients were recruited. Each patient at the admission and discharge was assessed with brief psychiatric rating scale (BPRS), eating attitude test (EAT-26), clinical global impression scale (CGI-S) and children global assessment scale (CGAS)...
August 21, 2017: International Journal of Psychiatry in Clinical Practice
https://www.readbyqxmd.com/read/28814972/mental-health-literacy-in-adolescents-ability-to-recognise-problems-helpful-interventions-and-outcomes
#16
Udena Ruwindu Attygalle, Hemamali Perera, Bernard Deepal Wanniarachchi Jayamanne
BACKGROUND: Although mental health literacy has been widely studied in adults, there are still relatively few studies on adolescent populations. In Sri Lanka, adolescents account for about one fifth of the population. Current evidence shows that most mental health problems diagnosed in adulthood begin in adolescence. There is also growing evidence that the trajectories of these disorders can be altered through early recognition and intervention. Although, help-seeking for mental health problems is known to be poor in adolescents, mental health literacy improves help-seeking...
2017: Child and Adolescent Psychiatry and Mental Health
https://www.readbyqxmd.com/read/28809752/association-of-obesity-and-health-related-quality-of-life-in-iranian-children-and-adolescents-the-weight-disorders-survey-of-the-caspian-iv-study
#17
Silva Hovsepian, Mostafa Qorbani, Mohammad Esmaeil Motlagh, Aryan Madady, Morteza Mansourian, Armita Mahdavi Gorabi, Roya Kelishadi
BACKGROUND: Considering the role of different ethnical, cultural and geographical factors in health related quality of life (HRQOL) as well as the perception of different populations regarding various weight disorders, we aimed to evaluate the association between body mass index (BMI) and HRQOL in Iranian children and adolescents. METHODS: This cross-sectional study was part of the Weight Disorders Survey of the CASPIAN-IV study. During this study, students aged 6-18 years from urban and rural areas of 30 provinces of Iran were selected...
August 28, 2017: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://www.readbyqxmd.com/read/28804465/personality-traits-related-to-binge-drinking-a-systematic-review
#18
REVIEW
Ana Adan, Diego A Forero, José Francisco Navarro
The pattern of alcohol consumption in the form of binge drinking (BD) or heavy episodic drinking has increased notably worldwide in recent years, especially among adolescent and young people, being currently recognized as a global health problem. Although only a minority of binge drinkers will develop a substance use disorder, BD may have negative personal and social consequences in the short and medium term. The objective of this article is to review the findings on personality traits related to binge drinkers and to emphasize the aspects that should be examined in order to make progress in this area...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/28801423/comparative-efficacy-and-acceptability-of-antidepressants-psychological-interventions-and-their-combination-for-depressive-disorder-in-children-and-adolescents-protocol-for-a-network-meta-analysis
#19
Xinyu Zhou, Andrea Cipriani, Yuqing Zhang, Pim Cuijpers, Sarah E Hetrick, John R Weisz, Juncai Pu, Cinzia Del Giovane, Toshiaki A Furukawa, Jürgen Barth, David Coghill, Stefan Leucht, Lining Yang, Arun V Ravindran, Peng Xie
INTRODUCTION: Depressive disorder is common in children and adolescents, with important consequences and serious impairments in terms of personal and social functioning. While both pharmacological and psychological interventions have been shown to be effective, there is still uncertainty about the balance between these and what treatment strategy should be preferred in clinical practice. Therefore, we aim to compare and rank in a network meta-analysis (NMA) the commonly used psychological, pharmacological and combined interventions for depressive disorder in children and adolescents...
August 11, 2017: BMJ Open
https://www.readbyqxmd.com/read/28795004/the-female-athlete-triad-special-considerations-for-adolescent-female-athletes
#20
REVIEW
Kelly A Brown, Aditya V Dewoolkar, Nicole Baker, Colleen Dodich
The number of adolescent girls participating in sports has dramatically increased throughout the last few decades. In the early 1990's, an association between amenorrhea, osteoporosis, and disordered eating was recognized and eventually labeled the 'Female Athlete Triad'. In 1997, the Task Force on Women's Issues of American College of Sports Medicine (ACSM) published a position statement on this triad of conditions that were becoming increasingly more prevalent amongst female athletes. Initially, the 'Female Athlete Triad' was characterized by disordered eating, amenorrhea, and osteoporosis...
July 2017: Translational pediatrics
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