keyword
https://read.qxmd.com/read/38285215/a%C3%A2-meta-analysis-of-melanoma-risk-in-idiopathic-inflammatory-myopathy-patients
#1
REVIEW
Rui Luo, Dan Xia, Siyang Yu
BACKGROUND: Idiopathic inflammatory myopathy (IIM) is a group of chronic acquired autoimmune diseases. The association between IIM and malignancies has been observed for decades. No meta-analysis has been conducted to summarize the relationship between IIM and melanoma. Herein, we specifically wanted to investigate whether IIM is associated with a higher incidence of melanoma. METHODS: We searched both Chinese and English databases (CNKI, VIP, Wanfang, PubMed, Embase, Web of Science) for studies on IIM related to melanoma published up to October 2023...
January 29, 2024: Zeitschrift Für Rheumatologie
https://read.qxmd.com/read/38230223/paraneoplastic-cutaneous-manifestations-of-hepatocellular-carcinoma-a-systematic-review-and-meta-analysis
#2
REVIEW
Laith Al-Showbaki, Ahmad A Toubasi, Dunia Z Jaber, Mohammad Al Shdifat, Noor Al-Maani, Omar Qudah, Feras Fararjeh, Eitan Amir
Background: There remains a scarcity of published data on the clinical significance of paraneoplastic cutaneous manifestations in hepatocellular carcinoma (HCC). Method: A systematic search of MEDLINE was performed in December 2022. Inclusion criteria comprised studies reporting on patients with HCC, who had paraneoplastic cutaneous manifestations. Outcomes of interests comprise survival and response to cancer-directed and/or skin directed therapy. Results: A total of 48 studies comprising 60 HCC patients were included in the analysis...
2024: Journal of Cancer
https://read.qxmd.com/read/38198130/causes-and-clinical-presentation-of-drug-induced-dermatomyositis-a-systematic-review
#3
JOURNAL ARTICLE
Sahar Caravan, Christopher M Lopez, Jennifer E Yeh
IMPORTANCE: While several medications are known to induce dermatomyositis (DM), most existing studies are case reports or small case series from a single institution. There is also limited information on DM induced by immune checkpoint inhibitors, which are increasingly used in oncologic therapy. OBJECTIVE: To characterize causes and clinical presentation of drug-induced DM based on the current literature. EVIDENCE REVIEW: A systematic review was performed in PubMed according to Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) reporting guidelines, from inception to August 22, 2022...
February 1, 2024: JAMA Dermatology
https://read.qxmd.com/read/37980696/efficacy-safety-and-the-lymphocyte-subset-changes-of-low-dose-il-2-in-patients-with-autoimmune-rheumatic-diseases-a-systematic-review-and-meta-analysis
#4
JOURNAL ARTICLE
Qinyi Su, Xinmiao Wang, Yongzhi Li, Jiexiang Zhang, Cairui Bai, Xuechun Wang, Liu Yang, Jingting Zhang, Sheng-Xiao Zhang
INTRODUCTION: Current therapies for autoimmune rheumatic diseases (ARDs) have limited efficacy in certain patients, highlighting the need for the development of novel treatment approaches. This meta-analysis aims to assess the efficacy and safety of low-dose interleukin-2 (LD-IL-2) and evaluate the alterations in lymphocyte subsets in various rheumatic diseases following administration of different dosages of LD-IL-2. METHODS: A comprehensive search was conducted in PubMed, Web of Science, the Cochrane Library, Embase databases and CNKI to identify relevant studies...
November 19, 2023: Rheumatology and Therapy
https://read.qxmd.com/read/37785833/acute-and-late-toxicities-in-patients-with-collagen-vascular-disease-receiving-curative-intent-intensity-modulated-radiotherapy-to-the-head-and-neck-region
#5
JOURNAL ARTICLE
L Ni, C Phuong, S S Yom, J Chan
PURPOSE/OBJECTIVE(S): Historically, collagen vascular disease (CVD) was considered at least a relative contraindication to radiotherapy (RT). However, more recent meta-analyses suggest that for patients with certain CVDs such as rheumatoid arthritis (RA), there may not be an increased risk for severe toxicities, while for patients with CVDs such as systemic lupus erythematosus (SLE), dermatomyositis (DM) and scleroderma, there may be as high as a 2- to 4-fold risk for severe toxicities compared to patients without CVD...
October 1, 2023: International Journal of Radiation Oncology, Biology, Physics
https://read.qxmd.com/read/37364274/predicting-the-death-of%C3%A2-patients-with-anti-melanoma-differentiation-associated-protein-5-positive-dermatomyositis-associated-interstitial-lung-disease-a-systematic-review-and%C3%A2-meta-analysis
#6
JOURNAL ARTICLE
Baolu Yang, Suying Liu, Zhenbei Qian, Zhaohui Tong
OBJECTIVES: To investigate the risk factors for death in anti-melanoma differentiation-associated protein-5-positive dermatomyositis-associated interstitial lung disease (ILD). METHODS: Studies were identified by searching PubMed, Embase, Web of Science, and Cochrane Library. We calculated pooled risk ratios (RRs) or standardized mean differences (SMDs) and 95% confidence intervals (CIs) using random-effects models. RESULTS: Twenty studies were selected...
May 18, 2023: Modern Rheumatology
https://read.qxmd.com/read/37348186/risk-factors-for-mortality-in-patients-with-anti-mda5-antibody-positive-dermatomyositis-a-meta-analysis-and-systematic-review
#7
JOURNAL ARTICLE
Huaiya Xie, Dingding Zhang, Yuanzhuo Wang, Yixin Shi, Yuan Yuan, Luo Wang, Junping Fan, Xinlun Tian, Jinglan Wang
OBJECTIVES: To determine the prognostic factors of dermatomyositis with anti-melanoma differentiation-associated gene 5 (MDA5) antibody, a rare disease and often complicated by life-threatening, rapidly progressive interstitial lung disease. METHODS: Herein, we searched the Medline, Embase, and Cochrane Library databases and extracted studies published before August 23, 2022. Pooled analysis of hazard ratios (HRs) or odds ratios was used to identify prognostic factors for mortality among patients with anti-MDA5 antibody-positive dermatomyositis (MDA5+ DM)...
October 2023: Seminars in Arthritis and Rheumatism
https://read.qxmd.com/read/37218538/autoimmune-skin-disorders-and-sars-cov-2-vaccination-a-meta-analysis
#8
JOURNAL ARTICLE
Julia Hinterseher, Michael Hertl, Dario Didona
BACKGROUND AND OBJECTIVES: The coronavirus SARS-CoV-2, which is the cause of COVID-19 disease in infected patients, has led to an ongoing worldwide pandemic. Although SARS-CoV-2 vaccination had a dramatic positive effect on the course of COVID-19, there has been increasing evidence of adverse effects after SARS-CoV-2 vaccination. This meta-analysis highlights the association between SARS-CoV-2 vaccination and de novo induction or aggravation of inflammatory and autoimmune skin diseases...
May 23, 2023: Journal der Deutschen Dermatologischen Gesellschaft: JDDG
https://read.qxmd.com/read/37164215/the-prevalence-and-effects-of-treatments-of-rapidly-progressive-interstitial-lung-disease-of-dermatomyositis-polymyositis-adults-a-systematic-review-and-meta-analysis
#9
REVIEW
Hongli Wang, Jiyang Lv, Juan He, Wenqi Wu, Yuchao Zhong, Siyang Cao, Yueming Cai, Qingwen Wang
Rapidly progressive interstitial lung disease (RP-ILD) clearly harms the prognoses of dermatomyositis/polymyositis (DM/PM) patients, however there is a dearth of numerical prevalence and therapy comparison in this field. Therefore, the purpose of this study was to determine the prevalence of RP-ILD in DM/PM patients and compare prognoses, including remission rate and survival data, between treatments. Studies with reports of RP-ILD in DM/PM patients and studies with definite remission and/or survival data of DM/PM-RP-ILD were included in the study...
August 2023: Autoimmunity Reviews
https://read.qxmd.com/read/37010885/a-systematic-review-and-meta-analysis-on-the-prevalence-and-clinical-characteristics-of-dysphagia-in-patients-with-dermatomyositis
#10
JOURNAL ARTICLE
Ivy Cheng, Christina Sze-Man Wong
BACKGROUND: Dermatomyositis (DM) is a rare autoimmune disease characterized by distinctive skin rash, muscle inflammation with symmetrical and progressive muscle weakness, and elevated serum levels of muscle-associated enzymes. DM may affect skeletal muscles involved in swallowing, leading to dysphagia, which can negatively impact individual's physical and psychosocial well-being. Despite this, dysphagia in patients with DM remains poorly understood. This systematic review and meta-analysis aimed to evaluate the prevalence and clinical features of dysphagia in patients with DM and juvenile DM (JDM)...
April 3, 2023: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://read.qxmd.com/read/36725399/the-efficacy-and-safety-of-tacrolimus-in-patients-with-dermatomyositis-polymyositis-a-meta-analysis-and-systematic-review
#11
JOURNAL ARTICLE
Jiafen Liao, Xiaofei Peng, Jiayi Liu, Xi Xie, Jia Wang
OBJECTIVE: To evaluate the efficacy and safety of tacrolimus for dermatomyositis (DM) and polymyositis (PM) treatment. METHODS: We searched the Embase, PubMed, the Cochrane Central Register of Controlled Trials, and China National Knowledge Infrastructure were used as searching tools from inception up to October 2022. Two authors independently selected studies. The available studies were comprehensively reviewed and investigated. RESULTS: A total of 9 studies, including 350 patients, were analysed...
April 2023: European Journal of Internal Medicine
https://read.qxmd.com/read/36578492/efficacy-and-safety-of-rituximab-treatment-in-patients-with-idiopathic-inflammatory-myopathies-a-systematic-review-and-meta-analysis
#12
Chao Zhen, Ying Hou, Bing Zhao, Xiaotian Ma, Tingjun Dai, Chuanzhu Yan
OBJECTIVE: Idiopathic inflammatory myopathies (IIMs) are a heterogeneous group of autoimmune diseases with various subtypes, myositis-specific antibodies, and affect multiple systems. The treatment of IIMs remains challenging, especially for refractory myositis. In addition to steroids and traditional immunosuppressants, rituximab (RTX), a B cell-depleting monoclonal antibody, is emerging as an alternative treatment for refractory myositis. However, the therapeutic response to RTX remains controversial...
2022: Frontiers in Immunology
https://read.qxmd.com/read/35821167/physical-exercise-for-dermatomyositis-and-polymyositis-a-systematic-review-and-meta-analysis
#13
JOURNAL ARTICLE
Beatriz Iwamoto Sercundes Leite da Silva, Beatriz Roberto Jorge Dos Santos, Julia Alves Carneiro, Fernanda Maximo Fonseca E Silva, Jean Marcos de Souza
Trials regarding physical exercise in dermatomyositis (DM) and polymyositis (PM) are heterogeneous. We aimed to summarize and critically analyze the available evidence to support the hypothesis that exercise is safe and improves strength and aerobic capacity. We performed a systematic review of clinical trials regarding physical exercise in dermatomyositis and polymyositis, without time restriction. We included studies from MEDLINE, EMBASE, SciELO, and Web of Science, published in English, Portuguese, or Spanish, and reporting outcomes related to safety, muscle performance, or aerobic capacity...
September 2022: Clinical Rheumatology
https://read.qxmd.com/read/35660927/the-therapeutic-efficacy-and-safety-of-intravenous-immunoglobulin-in-dermatomyositis-and-polymyositis-a-systematic-review-and-meta-analysis
#14
JOURNAL ARTICLE
Anji Xiong, Yiying Qiang, Yuzi Cao, Yu Shuai, Huini Chen, Qilang Xiang, Ziyi Hu, Zhuoyao Song, Shifeng Zhou, Yan Zhang, Hongxu Cui, Ye Wang, Jie Luo, Shiquan Shuai, Yuan Yang
OBJECTIVES: To evaluate the efficacy and safety of intravenous immunoglobulin (IVIG) in the treatment of dermatomyositis (DM) and polymyositis (PM). METHODS: A comprehensive systematic review was conducted in accordance with the guidelines of PRISMA (Preferred Reporting Items for Systematic Reviews And Meta-analyses). PubMed, Embase, and China National Knowledge Infrastructure (CNKI) were searched to find articles published between July 1919 and May 2021 concerning IVIG therapy in PM/DM...
June 4, 2022: Modern Rheumatology
https://read.qxmd.com/read/35134633/management-of-mda-5-antibody-positive-clinically-amyopathic-dermatomyositis-associated-interstitial-lung-disease-a-systematic-review
#15
REVIEW
Mark McPherson, Sofia Economidou, Andreas Liampas, Panagiotis Zis, Konstantinos Parperis
INTRODUCTION: Anti-melanoma differentiation-associated gene 5 (MDA5) antibody-positive clinically amyopathic dermatomyositis (CADM) is frequently associated with rapidly progressive interstitial lung disease (RP-ILD) and high mortality rates. There is a lack of data on management of this often fatal condition. The aim of this systematic review was to evaluate current evidence that assesses the available management options and discuss the associated management challenges. MATERIAL AND METHODS: This systematic review was conducted according to PRISMA guidelines...
April 2022: Seminars in Arthritis and Rheumatism
https://read.qxmd.com/read/35104319/a-systematic-review-and-meta-analysis-of-mycobacterial-infections-in-patients-with-idiopathic-inflammatory-myopathies
#16
JOURNAL ARTICLE
Saloni Haldule, Moumita Chatterjee, Rudra Prosad Goswami, Innara Vadsaria, Prithvi Gaur, Chengappa Kavadichanda, Durga Prasanna Misra, Hector Chinoy, Vikas Agarwal, Rohit Aggarwal, Latika Gupta
OBJECTIVES: Infections including Tuberculosis (TB) are a leading cause of morbidity and mortality in Idiopathic Inflammatory Myopathies (IIM). We systematically reviewed the prevalence of Mycobacterial infections in patients with IIM. METHODS: We screened PUBMED, EMBASE and SCOPUS databases and conference abstracts (2015-20) for original articles using Covidence. Pooled estimates of prevalence were calculated. RESULTS: Of 83 studies (28 cohort-studies, 2 case-control and 53 case reports), 19 were analysed...
February 1, 2022: Rheumatology
https://read.qxmd.com/read/34962996/comment-on-cardiovascular-events-in-adult-polymyositis-and-dermatomyositis-a-meta-analysis-of-observational-studies
#17
EDITORIAL
Li Qin, Han Wang
No abstract text is available yet for this article.
July 6, 2022: Rheumatology
https://read.qxmd.com/read/34962986/comment-on-cardiovascular-events-in-adult-polymyositis-and-dermatomyositis-a-meta-analysis-of-observational-studies-reply
#18
EDITORIAL
Ziyi Hu, Yuzi Cao, Yan Zhang, Qilang Xiang, Huini Chen, Zhuoyao Song, Yiying Qiang, Shifeng Zhou, Hongxu Cui, Jie Luo, Ye Wang, Yuan Yang, Xiaobo Xie, Wenjun Zhou, Shiquan Shuai, Anji Xiong
No abstract text is available yet for this article.
July 6, 2022: Rheumatology
https://read.qxmd.com/read/34910205/left-ventricle-diastolic-dysfunction-in-idiopathic-inflammatory-myopathies-a-meta-analysis-and-systematic-review
#19
JOURNAL ARTICLE
Yiwen Zhang, Xiaoqian Yang, Li Qin, Qiang Luo, Han Wang
OBJECTIVES: Recent studies have confirmed that heart failure is one of the most important causes of death in patients with idiopathic inflammatory myopathy (IIM). Left ventricle diastolic dysfunction (LVDD) is closely associated with heart failure. Our aim is to determine if the prevalence of LVDD is increased in IIM patients. METHODS: We performed a time- and language-restricted literature search to identify studies conducted to compare the echocardiographic parameters in IIM patients and controls...
April 18, 2022: Modern Rheumatology
https://read.qxmd.com/read/34887857/six-autoimmune-disorders-are-associated-with-increased-incidence-of-gastric-cancer-a-systematic-review-and-meta-analysis-of-half-a-million-patients
#20
JOURNAL ARTICLE
Noémi Zádori, Lajos Szakó, Szilárd Váncsa, Nóra Vörhendi, Eduard Oštarijaš, Szabolcs Kiss, Levente Frim, Péter Hegyi, József Czimmer
Background: Gastric cancer is one of the most common cancers worldwide, with a high mortality rate. The potential etiological role of autoimmune (AI) disorders has been described in gastric cancer; however, the literature is controversial. This study aims to provide a comprehensive summary of the association between autoimmune disorders and the incidence of gastric cancer. Methods: This study was registered on PROSPERO under registration number CRD42021262875. The systematic literature search was conducted in four scientific databases up to May 17, 2021...
2021: Frontiers in Immunology
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