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Middle cerebral artery doppler

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https://www.readbyqxmd.com/read/28547077/effects-of-the-combined-treatment-of-bone-marrow-stromal-cells-with-mild-exercise-and-thyroid-hormone-on-brain-damage-and-apoptosis-in-a-mouse-focal-cerebral-ischemia-model
#1
Kobar Akhoundzadeh, Abedin Vakili, Hamid Reza Sameni, Abbas Ali Vafaei, Ali Rashidy-Pour, Manouchehr Safari, Razieh Mohammadkhani
This study examined whether post-stroke bone marrow stromal cells (BMSCs) therapy combined with exercise (EX) and/or thyroid hormone (TH) could reduce brain damage in an experimental ischemic stroke in mice. Focal cerebral ischemia was induced under Laser Doppler Flowmetry (LDF) guide by 45 min of middle cerebral artery occlusion (MCAO), followed by 7 days of reperfusion in albino mice. BMSCs were injected into the right cerebral ventricle 24 h after MCAO, followed by daily injection of T3 (20 μg/100 g weight S...
May 25, 2017: Metabolic Brain Disease
https://www.readbyqxmd.com/read/28546663/comparison-of-outcome-of-normal-and-high-risk-pregnancies-based-upon-cerebroplacental-ratio-assessed-by-doppler-studies
#2
Anita Kant, Namrata Seth, Deepti Rastogi
OBJECTIVES: To evaluate the cerebroplacental ratio which is the ratio of pulsatility index of fetal middle cerebral and umbilical arteries, in normal and high-risk pregnancies during 30-36 weeks of gestation. METHODS: In this study, we included 70 patients, who were scanned for Doppler parameters of Middle cerebral artery and Umbilical artery pulsatility index ratio of fetus, between 30 and 36 weeks, and then were followed till delivery. Thirty-five patients with normal pregnancy and 35 patients with high-risk pregnancy were included...
June 2017: Journal of Obstetrics and Gynaecology of India
https://www.readbyqxmd.com/read/28539354/cerebral-oxygenation-and-regional-cerebral-perfusion-responses-with-resistance-breathing-during-central-hypovolemia
#3
Victoria L Kay, Justin Daniel Sprick, Caroline A Rickards
Resistance breathing improves tolerance to central hypovolemia induced by lower body negative pressure (LBNP), but this is not related to protection of anterior cerebral blood flow (indexed by mean middle cerebral artery velocity, MCAv). We hypothesized that inspiratory resistance breathing improves tolerance to central hypovolemia by maintaining cerebral oxygenation (ScO2), and protecting cerebral blood flow in the posterior cerebral circulation (indexed by posterior cerebral artery velocity, PCAv). Eight subjects (4M/4F) completed two experimental sessions of a presyncopal-limited LBNP protocol (3 mmHg/min onset rate) with and without (Control) resistance breathing via an impedance threshold device (ITD)...
May 24, 2017: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
https://www.readbyqxmd.com/read/28537493/the-relationship-between-cerebral-vasoreactivity-and-post-concussive-symptom-severity
#4
Tamadher Albalawi, Jason W Hamner, Matthew Lapointe, William Meehan, Can Ozan Tan
While pathophysiology underlying post-concussion symptom burden is unknown, data suggest that cerebrovascular dysfunction may be among the culprits. We sought to determine whether the degree of impairment in the ability of cerebrovasculature to buffer against changes in arterial gases (vasoreactivity) is associated with concussion symptoms. In 15 participants (19±5 years, 1 week to 1 year post-injury) diagnosed with concussion, we assessed vasoreactivity from the slope of the linear relationship of beat-by-beat middle cerebral artery blood flow velocity (transcranial Doppler ultrasound) to end-tidal CO<sub>2</sub> during progressive increases in end-tidal CO<sub>2</sub> (air rebreathing)...
May 24, 2017: Journal of Neurotrauma
https://www.readbyqxmd.com/read/28512500/the-effect-of-chunghyul-dan-on-hyperventilation-induced-carbon-dioxide-reactivity-of-the-middle-cerebral-artery-in-normal-subjects-a-dose-dependent-study
#5
Chul Jin, Sang-Kwan Moon, Seung-Yeon Cho, Seong-Uk Park, Woo-Sang Jung, Jung-Mi Park, Chang-Nam Ko, Ki-Ho Cho, Seungwon Kwon
Background. This study was conducted to show the prompt effect of chunghyul-dan (CHD) on cerebral hemodynamics in order to provide evidence for its use in stroke prevention. Methods. Hyperventilation-induced CO2 reactivity of the middle cerebral artery was measured in 12 healthy male volunteers (mean age: 26.3 ± 1.1 years) using transcranial Doppler sonography. All subjects were examined before and for 3 hours after administration, with an interval of 1 week between measurements. Results. Compared to baseline, the CO2 reactivity of the middle cerebral artery increased significantly at 2 and 3 hours after the administration of CHD (600 mg and 1200 mg)...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28503488/treatment-of-cerebral-vasospasm-in-an-infant-using-a-modified-dotter-technique
#6
Brian M Snelling, Samir Sur, Sumedh S Shah, Eric C Peterson
An 8-month old female presented with spontaneous subarachnoid hemorrhage and was treated successfully with endovascular coil embolization of the ruptured aneurysm. Transcranial Doppler ultrasound performed four days later demonstrated middle cerebral artery (MCA) velocities greater than 350 cm/sec on the right and greater than 200 cm/sec on the left, despite medical management. The patient demonstrated no focal neurological deficits, though examination was limited by our patient's sedation and intubation. Angiography revealed severe vasospasm of the supraclinoid internal carotid and MCA territories, bilaterally...
March 2017: Journal of Cerebrovascular and Endovascular Neurosurgery
https://www.readbyqxmd.com/read/28474984/carbon-monoxide-inhalation-induces-headache-in-a-human-headache-model
#7
Nanna Arngrim, Henrik Winther Schytz, Josefine Britze, Mark Bitsch Vestergaard, Mikael Sander, Karsten Skovgaard Olsen, Jes Olesen, Messoud Ashina
Introduction Carbon monoxide (CO) is an endogenously produced signalling molecule that has a role in nociceptive processing and cerebral vasodilatation. We hypothesized that inhalation of CO would induce headache and vasodilation of cephalic and extracephalic arteries. Methods In a randomized, double-blind, placebo-controlled crossover design, 12 healthy volunteers were allocated to inhalation of CO (carboxyhemoglobin 22%) or placebo on two separate days. Headache was scored on a verbal rating scale from 0-10...
January 1, 2017: Cephalalgia: An International Journal of Headache
https://www.readbyqxmd.com/read/28470726/measurement-of-blood-flow-velocity-in-the-middle-cerebral-artery-during-spontaneous-migraine-attacks-a-systematic-review
#8
REVIEW
Nisar A Shayestagul, Casper E Christensen, Faisal Mohammad Amin, Sait Ashina, Messoud Ashina
OBJECTIVE: To assess the evidence for blood flow velocity changes in the middle cerebral artery during and outside of spontaneous migraine attacks. METHODS: A systematic literature search on PubMed was performed and reference lists of assessed articles to identify studies on spontaneous migraine attacks that used transcranial Doppler on the middle cerebral artery with comparisons to interictal measurements were reviewed. Studies on non-spontaneous attacks and intervention studies were excluded...
May 3, 2017: Headache
https://www.readbyqxmd.com/read/28465403/middle-cerebral-artery-flow-velocity-increases-more-in-patients-with-delayed-intraparenchymal-hemorrhage-after-pipeline
#9
Denise Brunozzi, Sophia F Shakur, Ahmed E Hussein, Fady T Charbel, Ali Alaraj
OBJECTIVE: Pipeline Embolization Devices (PED) are commonly used for endovascular treatment of cerebral aneurysms but can be associated with delayed ipsilateral intraparenchymal hemorrhage (DIPH). The role that altered intracranial hemodynamics may play in the pathophysiology of DIPH is poorly understood. We assess middle cerebral artery (MCA) flow velocity changes after PED deployment. MATERIALS AND METHODS: Patients with aneurysms located proximal to the internal carotid artery terminus treated with PED at our institution between 2015 and 2016 were retrospectively reviewed...
May 2, 2017: Journal of Neurointerventional Surgery
https://www.readbyqxmd.com/read/28455103/transcranial-doppler-ultrasonography-in-the-assessment-of-neurovascular-coupling-responses-to-cognitive-examination-in-healthy-controls-a-feasibility-study
#10
C A L Williams, R B Panerai, T G Robinson, V J Haunton
BACKGROUND: We tested the hypothesis that paradigms from the Addenbrooke's Cognitive Examination (ACE-III), including those that had not been studied using TCD previously (novel) versus those which had been (established), would elicit changes in CBF velocity (CBFv). NEW METHOD: Healthy subjects were studied with bilateral transcranial Doppler (TCD), beat-to-beat blood pressure (Finapres), continuous electrocardiogram (ECG), and end-tidal CO2 (nasal capnography)...
April 26, 2017: Journal of Neuroscience Methods
https://www.readbyqxmd.com/read/28449077/executive-network-activation-is-linked-to-walking-speed-in-older-adults-functional-mri-and-tcd-ultrasound-evidence-from-the-mobilize-boston-study
#11
Azizah J Jor'dan, Victoria N Poole, Ikechukwu Iloputaife, William Milberg, Brad Manor, Michael Esterman, Lewis A Lipsitz
Background: Changes in cerebral blood flow velocity (CBF) in response to a cognitive task (task-related ΔCBF) have been shown by Transcranial Doppler ultrasonography (TCD) to be reduced in slow walkers. However, it is unknown whether reduced task-related ΔCBF is associated with reduced neural activity in specific brain regions, as measured by blood-oxygen-level dependent (BOLD) functional magnetic resonance imaging (fMRI). Methods: We assessed the regional changes in neural activity associated with reduced middle cerebral artery (MCA) task-related ΔCBF to an executive task and slow walking speed in 67 community-dwelling older adults from the MOBILIZE Boston Study...
April 26, 2017: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/28445296/a-case-of-cerebral-hyperperfusion-following-spontaneous-recanalization-of-occluded-middle-cerebral-artery-reperfusion-injury-or-true-cerebral-hyperperfusion-syndrome
#12
Ziqi Xu, Jiajia Zhou, Hui Liang, Benyan Luo, Ping Liu
BACKGROUND: Cerebral hyperperfusion syndrome (CHS) and reperfusion injury are distinct pathological phenomena. CASE SUMMARY: We present the case of a young ischemic stroke patient with middle cerebral artery (MCA) occlusion and spontaneous recanalization. Follow-up transcranial Doppler ultrasound showed high velocity flow in the left MCA, and neuroimaging revealed infarction, brain edema, artery dilatation, and hyperperfusion, consistent with both CHS and reperfusion injury...
April 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28441325/the-effects-of-taekwondo-training-on-peripheral-neuroplasticity-related-growth-factors-cerebral-blood-flow-velocity-and-cognitive-functions-in-healthy-children-a-randomized-controlled-trial
#13
Su-Youn Cho, Wi-Young So, Hee-Tae Roh
Although regular Taekwondo (TKD) training has been reported to be effective for improving cognitive function in children, the mechanism underlying this improvement remains unclear. The purpose of the present study was to observe changes in neuroplasticity-related growth factors in the blood, assess cerebral blood flow velocity, and verify the resulting changes in children's cognitive function after TKD training. Thirty healthy elementary school students were randomly assigned to control (n = 15) and TKD (n = 15) groups...
April 25, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28436705/pharmacologically-increasing-collateral-perfusion-during-acute-stroke-using-a-carboxyhemoglobin-gas-transfer-agent-sanguinate%C3%A2-in-spontaneously-hypertensive-rats
#14
Marilyn J Cipolla, Italo Linfante, Abe Abuchowski, Ronald Jubin, Siu-Lung Chan
Similar to patients with chronic hypertension, spontaneously hypertensive rats (SHR) develop fast core progression during middle cerebral artery occlusion (MCAO) resulting in large final infarct volumes. We investigated the effect of Sanguinate™ (SG), a PEGylated carboxyhemoglobin (COHb) gas transfer agent, on changes in collateral and reperfusion cerebral blood flow and brain injury in SHR during 2 h of MCAO. SG (8 mL/kg) or vehicle ( n = 6-8/group) was infused i.v. after 30 or 90 min of ischemia with 2 h reperfusion...
January 1, 2017: Journal of Cerebral Blood Flow and Metabolism
https://www.readbyqxmd.com/read/28436166/perinatal-loss-at-term-the-role-of-uteroplacental-and-fetal-doppler-assessment
#15
Caitriona Monaghan, Julia Binder, Baskaran Thilaganathan, José Morales-Roselló, Asma Khalil
OBJECTIVE: To examine the association of uterine artery (UtA) Doppler indices and cerebroplacental ratio (CPR) on perinatal outcome at term. METHODS: This retrospective cohort study conducted in a single tertiary referral centre included all singleton pregnancies undergoing ultrasound assessment in the third trimester, which subsequently delivered at term. Fetal biometry and Dopplers including the umbilical artery (UA), middle cerebral artery (MCA) and uterine artery were recorded...
April 24, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28435084/optimization-of-behavioural-tests-for-the-prediction-of-outcomes-in-mouse-models-of-focal-middle-cerebral-artery-occlusion
#16
Zhuoyu Wen, Xiaomeng Xu, Lili Xu, Lian Yang, Xiaohui Xu, Juehu A Zhu, Li Wu, Yongjun Jiang, Xinfeng Liu
Intraluminal middle cerebral artery occlusion (MCAO) is the most widely used model of stroke. We aimed to predict the outcome of MCAO using a combination of fine behavioural tests for the prediction of unsuccessful surgery in mice leading to no infarction, haemorrhage and unexpected death. MCAO was performed on adult mice under the guidance of laser-Doppler flowmetry (LDF) to warrant a decrease in regional cerebral blood flow (rCBF) in the MCA territory. Four outcomes of MCAO were defined according to histological analysis: infarction, no infarction, haemorrhage and unexpected death (death within 24 h post-surgery)...
April 20, 2017: Brain Research
https://www.readbyqxmd.com/read/28433837/internal-maxillary-bypass-for-complex-pediatric-aneurysms
#17
Long Wang, Shuaibin Lu, Hai Qian, Xiang'en Shi
BACKGROUND: Complex pediatric aneurysms (PAs) are an unusual clinicopathologic entity, and data remain limited regarding the use of a bypass procedure to treat this formidable disorder. METHODS: Internal maxillary artery (IMA) to middle cerebral artery (MCA) bypass with radial artery graft (RAG) was utilized to isolate PAs. Bypass patency and aneurysm stability were evaluated using intraoperative Doppler ultrasound, indocyanine green videoangiography and postoperative angiography...
April 19, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28431600/assessment-of-on-treatment-platelet-reactivity-and-relationship-with-cerebral-micro-embolic-signals-in-asymptomatic-and-symptomatic-carotid-stenosis
#18
Justin A Kinsella, W Oliver Tobin, Sean Tierney, Timothy M Feeley, Bridget Egan, Tara Coughlan, D Ronan Collins, Desmond O'Neill, Joseph A Harbison, Colin P Doherty, Prakash Madhavan, Dermot J Moore, Sean M O'Neill, Mary-Paula Colgan, Maher Saqqur, Raymond P Murphy, Niamh Moran, George Hamilton, Dominick J H McCabe
INTRODUCTION: The relationship between on-treatment platelet reactivity and cerebral micro-embolic signals (MES) is unknown, and has not been previously simultaneously assessed in asymptomatic and symptomatic carotid stenosis patients. METHODS: Consecutive eligible patients with ≥50% asymptomatic or recently symptomatic carotid stenosis (≤4weeks following TIA/ischaemic stroke) were recruited to this pilot study. Symptomatic patients were followed up to the 'late' phase (≥3months) following symptom onset or carotid intervention; longitudinal data were analysed from symptomatic patients with data available at both time-points...
May 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28427768/syndrome-of-transient-headache-and-neurological-deficits-with-cerebrospinal-fluid-lymphocytosis-handl-in-a-patient-with-confusional-symptoms-diffuse-eeg-abnormalities-and-bilateral-vasospasm-in-transcranial-doppler-ultrasound-a-case-report-and-literature-review
#19
M Hidalgo de la Cruz, R Domínguez Rubio, E Luque Buzo, F Díaz Otero, P Vázquez Alén, J Orcajo Rincón, J Prieto Montalvo, A Contreras Chicote, F Grandas Pérez
INTRODUCTION: HaNDL syndrome (transient headache and neurological deficits with cerebrospinal fluid lymphocytosis) is characterised by one or more episodes of headache and transient neurological deficits associated with cerebrospinal fluid lymphocytosis. To date, few cases of HaNDL manifesting with confusional symptoms have been described. Likewise, very few patients with HaNDL and confusional symptoms have been evaluated with transcranial Doppler ultrasound (TCD). TCD data from patients with focal involvement reveal changes consistent with vasomotor alterations...
April 17, 2017: Neurología: Publicación Oficial de la Sociedad Española de Neurología
https://www.readbyqxmd.com/read/28417646/cerebral-hemodynamic-assessment-and-neuroimaging-across-the-lifespan-in-sickle-cell-disease
#20
Lori C Jordan, Michael R DeBaun
Children and adults with sickle cell anemia (SCA) have a higher risk of strokes compared to age- and race-matched peers. Velocity in the middle cerebral or distal internal carotid artery as measured by transcranial Doppler ultrasound is a recognized method to identify children but not adults with SCA at high-risk for first stroke. For both children and adults with SCA that have had a stroke, no methods clearly identify individuals at highest risk of recurrent strokes or an initial silent stroke, the most common neurological injury...
January 1, 2017: Journal of Cerebral Blood Flow and Metabolism
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