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Middle cerebral artery doppler

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https://www.readbyqxmd.com/read/29130477/transcranial-doppler-and-lower-extremity-function-in-older-adults-einstein-aging-study
#1
Ali Ezzati, Tatjana Rundek, Joe Verghese, Carol A Derby
OBJECTIVES: To determine whether transcranial Doppler ultrasound (TCD) measures of mean blood flow velocity (MBFV) in the major cerebral arteries are associated with measures of lower extremity function in community-dwelling older adults. DESIGN: Cross-sectional study. SETTING: Community sample. PARTICIPANTS: Individuals aged 70 and older (mean 79.5, 54% female) without dementia participating in the Einstein Aging Study (N = 200)...
November 11, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/29129735/arterial-stiffness-and-cerebral-hemodynamic-pulsatility-during-cognitive-engagement-in-younger-and-older-adults
#2
Kevin S Heffernan, Jacqueline A Augustine, Wesley K Lefferts, Nicole L Spartano, William E Hughes, Randall S Jorgensen, Brooks B Gump
This study examined central artery stiffness and hemodynamic pulsatility during cognitive engagement in younger and older adults. METHODS: Vascular-hemodynamic measures were completed in 19 younger (age 35±1yrs) and 20 older (age 69±2yrs) adults at rest and during a Stroop task. Aortic stiffness (carotid-femoral pulse wave velocity, PWV) and carotid pulse pressure (PP) were assessed using applanation tonometry. Carotid stiffness was assessed as a single-point PWV using Doppler Ultrasound...
November 9, 2017: Experimental Gerontology
https://www.readbyqxmd.com/read/29121743/profiling-of-cardiovascular-and-cerebrovascular-disease-associated-microrna-expression-in-umbilical-cord-blood-in-gestational-hypertension-preeclampsia-and-fetal-growth-restriction
#3
Ilona Hromadnikova, Katerina Kotlabova, Katarina Ivankova, Yulia Vedmetskaya, Ladislav Krofta
BACKGROUND AND METHODS: Gene expression of 29 cardiovascular and cerebrovascular disease associated microRNAs was assessed in whole umbilical cord blood, compared between groups [47 gestational hypertension (GH), 56 preeclampsia (PE), 37 fetal growth restriction (FGR) and 44 normal pregnancies] and correlated with the severity of the disease with respect to clinical signs (mild PE vs. severe PE), delivery date (before and after 34weeks of gestation), and Doppler ultrasound parameters [pulsatility index (PI) in the umbilical artery, PI in the middle cerebral artery and the cerebroplacental ratio]...
December 15, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/29111029/hematoma-volume-is-a-predictive-factor-of-disturbed-autoregulation-after-spontaneous-intracerebral-hemorrhage
#4
Hongyin Ma, Zhen-Ni Guo, Xin Sun, Jia Liu, Shan Lv, Lu Zhao, Weitong Guo, Hang Jin, Yi Yang
BACKGROUND: Dynamic cerebral autoregulation (dCA) is probably disturbed after spontaneous intracerebral hemorrhage (ICH) and could be an independent predictor of clinical outcome. Clinical determinants of dCA status after ICH need to be further elucidated. METHODS: We finally enrolled 53 patients diagnosed with supratentorial ICH within 6days from onset. DCA was assessed 4-6days after ICH onset by monitoring middle cerebral artery blood flow velocities and simultaneous arterial blood pressure continuously, utilizing transcranial Doppler combined with a servo-controlled finger plethysmograph...
November 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/29103148/cerebrovascular-co2-reactivity-during-isoflurane-nitrous-oxide-anesthesia-in-patients-with-chronic-renal-failure
#5
Kazuyoshi Ishida, Masato Uchida, Kohji Utada, Atsuo Yamashita, Satoshi Yamashita, Shiro Fukuda, Mishiya Matsumoto, Takefumi Sakabe
PURPOSE: We assessed the cerebrovascular CO2 reactivity (CO2R) in chronic renal failure (CRF) patients without diabetes mellitus (DM), uncontrolled hypertension, peripheral vascular disease, or neurological disease under isoflurane-nitrous oxide anesthesia. METHODS: Forty-nine patients undergoing surgery, including 36 CRF patients (30 receiving dialysis and six pre-dialysis patients) and 13 patients without CRF (controls). Middle cerebral artery flow velocity (VMCA) was measured by transcranial Doppler ultrasonography at an end-tidal CO2 of 35 to 45 mmHg...
November 4, 2017: Journal of Anesthesia
https://www.readbyqxmd.com/read/29091282/correlation-between-maternal-anxiety-reactivity-of-fetal-cerebral-circulation-to-auditory-stimulation-and-birth-outcome-in-normotensive-and-gestational-hypertensive-women
#6
Marina Vujović, Mirjana Sovilj, Ljiljana Jeličić, Miodrag Stokić, Darko Plećaš, Snežana Plešinac, Nadežda Nedeljković
This study investigated the correlation between maternal anxiety and blood flow changes through the fetal middle cerebral artery (MCA) after defined acoustic stimulation in 43 normotensive (C) and 40 gestational hypertensive (GH) subjects. Neonatal outcomes (gestational age at birth, Apgar score, birth weight) in the C and GH groups were analyzed. State (STAI-S) and trait (STAI-T) anxiety was assessed using Spielberger's questionnaire. The MCA blood flow was assessed once between 28 and 41 weeks of gestation using color Doppler ultrasound before and after application of defined acoustic stimulus...
November 1, 2017: Developmental Psychobiology
https://www.readbyqxmd.com/read/29091052/transcranial-doppler-of-the-middle-cerebral-artery-indicates-regional-gray-matter-cerebral-perfusion
#7
Evan P Pasha, Takashi Tarumi, Andreana P Haley, Hirofumi Tanaka
INTRODUCTION: We determined if transcranial color-coded Doppler derived hemodynamics are associated with MRI based cerebral blood flow (CBF) in regions clinically important to dementia in healthy middle-aged adults. METHODS: In thirty subjects (18m/12f; age=52±1 years), blood flow velocity (BFV) and cerebrovascular conductance (CVC) were measured with transcranial color-coded Doppler (TCCD) at the middle cerebral artery (MCA) and cerebral blood flow (CBF) was assessed with arterial spin labeled perfusion MRI...
November 1, 2017: Physiological Measurement
https://www.readbyqxmd.com/read/29075198/impacts-of-simulated-weightlessness-by-dry-immersion-on-optic-nerve-sheath-diameter-and-cerebral-autoregulation
#8
Marc Kermorgant, Florian Leca, Nathalie Nasr, Marc-Antoine Custaud, Thomas Geeraerts, Marek Czosnyka, Dina N Arvanitis, Jean-Michel Senard, Anne Pavy-Le Traon
Dry immersion (DI) is used to simulate weightlessness. We investigated in healthy volunteers if DI induces changes in ONSD, as a surrogate marker of intracranial pressure (ICP) and how these changes could affect cerebral autoregulation (CA). Changes in ICP were indirectly measured by changes in optic nerve sheath diameter (ONSD). 12 healthy male volunteers underwent 3 days of DI. ONSD was indirectly assessed by ocular ultrasonography. Cerebral blood flow velocity (CBFV) of the middle cerebral artery was gauged using transcranial Doppler ultrasonography...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/29056995/magnetic-resonance-imaging-and-clinical-outcome-in-patients-with-symptomatic-carotid-artery-stenosis-after-carotid-artery-revascularization
#9
Rafał Badacz, Anna Kabłak-Ziembicka, Małgorzata Urbańczyk-Zawadzka, Robert P Banyś, Piotr Musiałek, Piotr Odrowąż-Pieniążek, Mariusz Trystuła, Jan Ścigalski, Krzysztof Żmudka, Tadeusz Przewłocki
INTRODUCTION: About 30% of patients with carotid artery stenosis (CAS) develop dementia after a cerebral ischemic event (CIE), and 20-50% suffer from CIE recurrence during 6 months. Carotid artery revascularization (CAR) may prevent CIE recurrence, at the cost of new microembolic lesions (MES). The impact of CAR on cognitive function is debatable. AIM: To assess functional and cognitive outcome, cerebral flow on transcranial Doppler (TCD) and brain magnetic resonance imaging (MRI) in patients with symptomatic CAS referred for CAR...
2017: Postępy W Kardiologii Interwencyjnej, Advances in Interventional Cardiology
https://www.readbyqxmd.com/read/29054860/post-prandial-hyperlipidaemia-results-in-systemic-nitrosative-stress-and-impaired-cerebrovascular-function-in-the-aged
#10
Christopher J Marley, Danielle Hodson, Julien V Brugniaux, Lewis Fall, Damian Miles Bailey
Post-prandial hyperlipidaemia (PPH) acutely impairs systemic vascular endothelial function, potentially attributable to a free radical-mediated reduction in vascular nitric oxide (NO) bioavailability (oxidative-nitrosative stress). However, it remains to be determined whether this extends to the cerebrovasculature. To examine this, 38 (19 young (≤ 35 years) and 19 aged (≥ 60 years)) healthy males were recruited. Cerebrovascular function (middle cerebral artery velocity, MCAv) and cerebrovascular reactivity to hypercapnea (CVRCO2Hyper) and hypocapnea (CVRCO2Hypo) were determined via trans-cranial Doppler ultrasound and capnography...
October 20, 2017: Clinical Science (1979-)
https://www.readbyqxmd.com/read/29044294/serum-levels-of-anti-pon1-and-anti-hdl-antibodies-as-potential-biomarkers-of-premature-atherosclerosis-in-systemic-lupus-erythematosus
#11
Patricia López, Javier Rodríguez-Carrio, Aleida Martínez-Zapico, Ángel I Pérez-Álvarez, Raquel López-Mejías, Lorena Benavente, Lourdes Mozo Mozo, Luis Caminal-Montero, Miguel A González-Gay, Ana Suárez
The present study aimed to evaluate the possible role of immunoglobulin G (IgG) antibodies against high-density lipoproteins (HDL) and paraoxonase 1 (PON1) as possible biomarkers of cardiovascular disease (CVD) in systemic lupus erythematosus (SLE). To this end, levels of these autoantibodies, PON1 activity and total antioxidant capacity were quantified in serum samples from 198 SLE patients, 100 healthy controls (HC) and 42 non-autoimmune individuals with traditional cardiovascular risk factors. PON1 rs662 polymorphism was analysed in a subgroup of patients and controls...
October 10, 2017: Thrombosis and Haemostasis
https://www.readbyqxmd.com/read/29043564/the-ucp2-866g-a-polymorphism-could-be-considered-as-a-genetic-marker-of-different-functional-prognosis-in-ischemic-stroke-after-recanalization
#12
I Díaz-Maroto Cicuéndez, E Fernández-Díaz, J García-García, J Jordán, I Fernández-Cadenas, J Montaner, G Serrano-Heras, T Segura
Recent studies based on experimental animal models of stroke have suggested that uncoupling protein 2 (UCP2), an inner mitochondrial membrane protein that is thought to regulate energy metabolism and reduce reactive oxygen species generation, provides protection against reperfusion damage. We aimed to investigate whether -866G/A polymorphism in the promoter of the UCP2 gene, which enhances its transcriptional activity, is associated with functional prognosis in patients with embolic ischemic stroke after early recanalization...
December 2017: Neuromolecular Medicine
https://www.readbyqxmd.com/read/29034765/assessment-of-maternal-cerebral-blood-flow-velocity-by-transcranial-doppler-ultrasound-before-delivery-and-in-the-early-postpartum-period
#13
Hale Z Batur Caglayan, Bijen Nazliel, Mehmet Cinar, Esra Ataoglu, Ozlem Moraloglu, Ceyla Irkec
OBJECTIVE: This prospective observational study aimed to identify the effects of labor on cerebral hemodynamics by measuring the middle cerebral artery (MCA) blood flow velocity by transcranial Doppler ultrasound (TCD), and the related factors just before delivery and within the 24 h after delivery. METHODS: The study included 35 healthy pregnant women with a gestational age of >37 weeks who were in labor and a control group including healthy, age-matched, nonpregnant women (n = 24)...
October 16, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29025748/compromised-cerebrovascular-regulation-and-cerebral-oxygenation-in-pulmonary-arterial-hypertension
#14
Simon Malenfant, Patrice Brassard, Myriam Paquette, Olivier Le Blanc, Audrey Chouinard, Valérie Nadeau, Philip D Allan, Yu-Chieh Tzeng, Sébastien Simard, Sébastien Bonnet, Steeve Provencher
BACKGROUND: Functional cerebrovascular regulatory mechanisms are important for maintaining constant cerebral blood flow and oxygen supply in heathy individuals and are altered in heart failure. We aim to examine whether pulmonary arterial hypertension (PAH) is associated with abnormal cerebrovascular regulation and lower cerebral oxygenation and their physiological and clinical consequences. METHODS AND RESULTS: Resting mean flow velocity in the middle cerebral artery mean flow velocity in the middle cerebral artery (MCAvmean); transcranial Doppler), cerebral pressure-flow relationship (assessed at rest and during squat-stand maneuvers; analyzed using transfer function analysis), cerebrovascular reactivity to CO2, and central chemoreflex were assessed in 11 patients with PAH and 11 matched healthy controls...
October 12, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29017899/a-brain-computer-interface-based-on-functional-transcranial-doppler-ultrasound-using-wavelet-transform-and-support-vector-machines
#15
Aya Khalaf, Matthew Sybeldon, Ervin Sejdic, Murat Akcakaya
BACKGROUND: Functional transcranial Doppler (fTCD) is an ultrasound based neuroimaging technique used to assess neural activation that occurs during a cognitive task through measuring velocity of cerebral blood flow. NEW METHOD: The objective of this paper is to investigate the feasibility of a 2-class and 3-class real-time BCI based on blood flow velocity in left and right middle cerebral arteries in response to mental rotation and word generation tasks. Statistical features based on a five-level wavelet decomposition were extracted from the fTCD signals...
October 7, 2017: Journal of Neuroscience Methods
https://www.readbyqxmd.com/read/28992237/impacts-of-metabolic-syndrome-scores-on-cerebrovascular-conductance-are-mediated-by-arterial-stiffening
#16
Evan P Pasha, Alex C Birdsill, Stephanie Oleson, Andreana P Haley, Hirofumi Tanaka
BACKGROUND: Individuals with metabolic syndrome (MetS) exhibit reduced cerebral blood flow. The mechanisms of this reduction remain unknown but arterial stiffening has been implicated as a contributor. We determined if MetS was associated with reduced cerebral blood flow at midlife, and if so, whether arterial stiffness was responsible for mediating their relation. METHODS: Middle-aged (40-60 years) community dwelling adults (n = 83) were studied. MetS score was calculated for each subject...
July 31, 2017: American Journal of Hypertension
https://www.readbyqxmd.com/read/28991047/vasopressors-do-not-influence-cerebral-critical-closing-pressure-during-systemic-inflammation-evoked-by-experimental-endotoxemia-and-sepsis-in-humans
#17
Judith Maria Dimphena van den Brule, Roeland Stolk, Elisabeth Janine Vinke, Lex Maxim van Loon, Peter Pickkers, Johannes Gerardus van der Hoeven, Matthijs Kox, Cornelia Wilhelmina Elisabeth Hoedemaekers
AIM: The aim of this study was to investigate the effects of different vasopressors on the cerebral vasculature during experimental human endotoxemia and sepsis. We used the critical closing pressure (CrCP) as a measure of cerebral vascular tone. METHODS: We performed a prospective pilot study, at the intensive care department (ICU) of a tertiary care university hospital in the Netherlands, in 40 healthy male subjects during experimental human endotoxemia (administration of bacterial lipopolysaccharide [LPS]) and in 10 patients with severe sepsis or septic shock...
October 4, 2017: Shock
https://www.readbyqxmd.com/read/28987853/early-hemodynamic-changes-based-on-initial-color-coding-angiography-as-a-predictor-for-developing-subsequent-symptomatic-vasospasm-after-aneurysmal-sah
#18
Jan-Karl Burkhardt, Xiaolin Chen, Ethan A Winkler, Miriam Weiss, John Yue, Daniel L Cooke, Helen Kim, Michael T Lawton
INTRODUCTION: Prediction of vasospasm following aneurysmal subarachnoid hemorrhage (aSAH) remains imperfect and currently relies on clinical and radiographic characteristics. Whether early hemodynamic changes may refine risk stratification for delayed vasospasm (DV) after aSAH was analyzed. METHODS: Patients with aSAH (n=53) and a control of unruptured intracranial aneurysms (UIA) (n=12) with initial color-coding angiography at admission were included in this study (n=65)...
October 5, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28985690/influence-of-high-flow-modified-ultrafiltration-on-brain-oxygenation-and-perfusion-during-surgery-for-children-with-ventricular-septal-defects-a-pilot-study
#19
Zaishen Jia, Yichao Teng, Yuan Liu, Hong Wang, Yue Li, Xiaotong Hou
BACKGROUND: Modified ultrafiltration (MUF) can be performed in infants with ventricular septal defects (VSDs) after cardiopulmonary bypass (CPB) to reduce haemodilution and its potential adverse effects. High-flow MUF might reduce ultrafiltration duration and hasten the necessary correction of haemodilution during CPB. However, its influence on brain oxygenation remains controversial. OBJECTIVE: This non-randomized, prospective, pilot study aimed to investigate the influence of high-flow MUF on brain oxygenation in infants with VSDs...
October 1, 2017: Perfusion
https://www.readbyqxmd.com/read/28982294/the-effect-of-prenatal-alcohol-exposure-on-fetal-growth-and-cardiovascular-parameters-in-a-baboon-model-of-pregnancy
#20
Ana M Tobiasz, Jose R Duncan, Zoran Bursac, Ryan D Sullivan, Danielle L Tate, Alex M Dopico, Anna N Bukiya, Giancarlo Mari
Prenatal alcohol exposure often results in an array of fetal developmental abnormalities termed fetal alcohol spectrum disorders (FASDs). Despite the high prevalence of FASDs, the pathophysiology of fetal damage by alcohol remains poorly understood. One of the major obstacles in studying fetal development in response to alcohol exposure is the inability to standardize the amount, pattern of alcohol consumption, and peak blood alcohol levels in pregnant mothers. In the present study, we used Doppler ultrasonography to assess fetal growth and cardiovascular parameters in response to alcohol exposure in pregnant baboons...
January 1, 2017: Reproductive Sciences
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