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https://www.readbyqxmd.com/read/29025483/depressive-symptoms-and-hazardous-harmful-alcohol-use-are-prevalent-and-correlate-with-stigma-among-tb-hiv-patients-in-lesotho
#1
E Hayes-Larson, Y Hirsch-Moverman, S Saito, K Frederix, B Pitt, L Maama-Maime, A A Howard
SETTING: Limited data exist on the prevalence and correlates, including stigma, of mental health conditions, including depressive symptoms and alcohol use, among patients co-infected with tuberculosis (TB) and the human immunodeficiency virus (HIV) in sub-Saharan Africa, despite their negative impact on health outcomes. OBJECTIVE: To assess the prevalence and correlates of depressive symptoms and hazardous/harmful alcohol use among TB-HIV patients in the Start TB patients on ART and Retain on Treatment (START) study...
November 1, 2017: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/29017605/collaborative-shared-care-to-improve-psychosis-outcome-cosimpo-study-protocol-for-a-randomized-controlled-trial
#2
Oye Gureje, Victor Makanjuola, Lola Kola, Bidemi Yusuf, Leshawndra Price, Oluyomi Esan, Bibilola D Oladeji, John Appiah-Poku, Benjamin Haris, Caleb Othieno, Soraya Seedat
BACKGROUND: Psychotic disorders are a group of severe mental disorders that cause considerable disability to sufferers and a high level of burden to families. In many low- and middle-income countries (LMIC), traditional and faith healers are the main providers of care to affected persons. Even though frequently canvassed as desirable for improved care delivery, collaboration between these complementary alternative health providers (CAPs) and conventional health providers has yet to be rigorously tested for feasibility and effectiveness on patient outcomes...
October 10, 2017: Trials
https://www.readbyqxmd.com/read/29017595/a-series-of-n-of-1-trials-to-assess-the-therapeutic-interchangeability-of-two-enalapril-formulations-in-the-treatment-of-hypertension-in-addis-ababa-ethiopia-study-protocol-for-a-randomized-controlled-trial
#3
Chalachew Alemayehu, Geoffrey Mitchell, Abraham Aseffa, Alexandra Clavarino, James McGree, Jane Nikles
BACKGROUND: Hypertension is one of the leading causes of morbidity and mortality in Ethiopia. Treatment usually involves lifelong medication use. Enalapril is a common drug for the treatment of hypertension in Ethiopia. However, the drug is expensive and, therefore, there is limited capacity for people to afford the treatment. Locally produced Enalapril is a cost-effective solution to treat the disease. However, as local medicines regulation does not include bioequivalence tests on locally produced drugs, physicians and patients need assurance about the effectiveness and safety of local generics...
October 10, 2017: Trials
https://www.readbyqxmd.com/read/29016275/effectiveness-of-psychoanalytic-interactional-group-therapy-vs-behavioral-group-therapy-in-routine-outpatient-treatment-of-alcohol-dependent-patients
#4
Peter W Nyhuis, Eva Niederhofer, Norbert Scherbaum, Fabrizio Schifano, Udo Bonnet, Nikolai Dembski, Anna Niederhofer, Michael Specka, Meike Tenbergen
BACKGROUND: The cognitive behavioral therapy has been extensively investigated to assess relapse prevention rates in patients with alcohol dependence. In contrast, only little is known regarding the effectiveness of psychoanalytical psychotherapy in relapse prevention, although this treatment is widely used and especially so in Germany. The aim of this quasi-randomized study was to compare the effectiveness of these two group treatments' approaches under the condition of routine outpatient treatment in a non-university hospital...
October 10, 2017: Substance Use & Misuse
https://www.readbyqxmd.com/read/28992822/therapy-update-for-insomnia-in-the-elderly
#5
Sum Lam, Lucy O Macina
OBJECTIVE: To offer an update on insomnia in older adults and treatment options. DATA SOURCES: A search of PubMed using the terms "insomnia" and "older adults" was performed. Current guidelines, review articles, and drug database and manufacturer package inserts were utilized to provide relevant information. STUDY SELECTION: All English-language articles from 2012 to February 2017 and their bibliographies were reviewed for relevance. Current guidelines from the American College of Physicians, the American Academy of Sleep Medicine, and the American Geriatrics Society's Beers criteria were reviewed...
October 1, 2017: Consultant Pharmacist: the Journal of the American Society of Consultant Pharmacists
https://www.readbyqxmd.com/read/28989140/comparative-evaluation-of-myeloperoxidase-enzymatic-activity-in-gingival-crevicular-fluid-of-subjects-having-orthodontic-treatment-by-different-aligning-arch-wires
#6
Vinny Bhasin, Madhavi Singh, Manish Goutam, Shuchi Singh, Adamya S Nigam, Aditya Joshi
INTRODUCTION: There exist a number of factors that affect the outcome of orthodontic treatment. These factors can be assessed by various gingival markers. One such maker is myeloperoxidase (MPO). Hence, we planned the present study to assess and compare the MPO activity in the gingival crevicular fluid (GCF) of subjects undergoing orthodontic treatment by different aligning arch wires. MATERIALS AND METHODS: The present study included assessment of patients who underwent orthodontic treatment for crowding of anterior teeth...
October 1, 2017: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/28985201/-good-things-come-in-small-packages-application-of-exosome-based-therapeutics-in-neonatal-lung-injury
#7
REVIEW
Gareth R Willis, S Alex Mitsialis, Stella Kourembanas
Infants born at very low gestational age contribute disproportionately to neonatal morbidity and mortality. Advancements in antenatal steroid therapies and surfactant replacement have favored the survival of infants with ever-more immature lungs. Despite such advances in medical care, cardiopulmonary and neurological impairment prevail in constituting the major adverse outcomes for neonatal intensive care unit (NICU) survivors. With no single effective therapy for either the prevention or treatment of such neonatal disorders, the need for new tools to treat and reduce risk of further complications associated with extreme preterm birth is urgent...
October 6, 2017: Pediatric Research
https://www.readbyqxmd.com/read/28981832/cognitive-predictors-of-work-among-social-security-disability-insurance-beneficiaries-with-psychiatric-disorders-enrolled-in-ips-supported-employment
#8
Susan R McGurk, Robert E Drake, Haiyi Xie, Jarnee Riley, Roline Milfort, Thomas W Hale, William Frey
BACKGROUND: Impaired cognitive functioning is a significant predictor of work dysfunction in schizophrenia. Less is known, however about relationships of cognition and work in people with less severe disorders with relatively normal cognitive functioning. METHODS: This secondary analysis evaluated cognitive predictors of work in Social Security Disability Insurance (SSDI) beneficiaries with a recent work history who were randomized to receive mental health services, supported employment, and freedom from work disincentives over a 2-year study period in the Mental Health Treatment Study...
August 31, 2017: Schizophrenia Bulletin
https://www.readbyqxmd.com/read/28969250/prevalence-of-helicobacter-pylori-infection-and-stress-anxiety-or-depression-in-functional-dyspepsia-and-outcome-after-appropriate-intervention
#9
Kirti Katherine Kabeer, Nilakanthan Ananthakrishnan, Chetan Anand, Sivaprakash Balasundaram
INTRODUCTION: The association between psychological factors and non-ulcer dyspepsia remains controversial. AIM: To determine the prevalence of Helicobacter pylori (HP) and Stress/Anxiety/Depression (SAD) in patients with Functional Dyspepsia (FD) and assess the outcome at three months after appropriate intervention. MATERIALS AND METHODS: This prospective non-randomized interventional study was conducted on 120 patients with FD. Initial workup included upper gastrointestinal endoscopy to confirm HP infection with either of two tests, the urease test or histopathology...
August 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28960019/yoga-as-part-of-a-package-of-care-versus-standard-care-for-schizophrenia
#10
REVIEW
Julie Broderick, Davy Vancampfort
BACKGROUND: Yoga is an ancient spiritual practice that originated in India and is currently accepted in the Western world as a form of relaxation and exercise. It has been of interest for people with schizophrenia to determine the efficacy of yoga delivered as a package of care versus standard care. OBJECTIVES: To examine the effects of yoga as a package of care versus standard care. SEARCH METHODS: We searched the Cochrane Schizophrenia Group Trials Register (latest 30 March 2017) which is based on regular searches of MEDLINE, PubMed, Embase, CINAHL, BIOSS, AMED, PsychINFO, and registries of clinical trials...
September 29, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28951029/bacterial-contamination-of-endodontic-materials-before-and-after-clinical-storage
#11
Media Saeed, Garrit Koller, Sadia Niazi, Shanon Patel, Francesco Mannocci, Kenneth Bruce, Federico Foschi
INTRODUCTION: The aim of this study was to evaluate the bacterial contamination in endodontic consumables (gutta-percha points, rubber dams, paper mixing pads, caulking agents, and endodontic instrument sponges [EISs]) before and after clinical use and storage. METHODS: Materials were randomly sampled in triplicates at 3 time points (t0, at package opening; t1, at 7 days; and t2, at 14 days) during their clinical usage. The gutta-percha points and caulking agent (25 mg) were added to 1 mL phosphate-buffered saline (PBS)...
September 23, 2017: Journal of Endodontics
https://www.readbyqxmd.com/read/28948115/evaluating-the-role-of-zinc-in-beta-thalassemia-major-a-prospective-case-control-study-from-a-tertiary-care-teaching-hospital-in-india
#12
Sujana Nidumuru, Venugopal Boddula, Sabitha Vadakedath, Bhagavan Reddy Kolanu, Venkataramana Kandi
Background Thalassemia is a common hereditary anemia in humans, and beta thalassemia represents a group of recessively inherited hemoglobin disorders first described by Cooley and Lee and characterized by the abnormal synthesis of β-globin chain. The homozygous state results in severe anemia, which needs regular blood transfusion. Although such treatments increase the patient's life span, a variety of complications, including endocrine, metabolic, skeletal, and growth disorders are being observed due to increased iron storage in the body...
July 20, 2017: Curēus
https://www.readbyqxmd.com/read/28928319/effect-of-a-brief-smoking-cessation-intervention-on-adult-tobacco-smokers-with-pulmonary-tuberculosis-a-cluster-randomized-controlled-trial-from-north-india
#13
Sonu Goel, Jeyashree Kathiresan, Preeti Singh, Rana J Singh
BACKGROUND: An association between smoking and poor tuberculosis (TB) treatment outcomes has been globally established. Various smoking cessation interventions (SCIs) have been proven worldwide to curb smoking behavior. There is a need for evidence to assess if SCI increases the chance of successful treatment outcome among TB patients. OBJECTIVES: To assess the effectiveness of a brief SCI; The Ask, Brief, Cessation support (ABC) package, on treatment outcomes and smoking cessation in smear-positive adult pulmonary TB patients...
September 2017: Indian Journal of Public Health
https://www.readbyqxmd.com/read/28919793/burden-of-uterine-fibroids-in-italy-epidemiology-treatment-outcomes-and-consumption-of-health-care-resources-in-more-than-5-000-women
#14
Marco Chiumente, Mauro De Rosa, Andrea Messori, Enrica Maria Proli
BACKGROUND AND PURPOSE: Epidemiological studies on uterine fibroids (UFs) are mostly based on surveys or analyses of small samples of patients. In 50% of women, the quality of life is worsened by disease-related symptoms; furthermore, treatments imply a remarkable health care cost. The aim of this observational study was to analyze a large sample of Italian patients with UFs and to assess the epidemiology, the appropriateness of treatments, and the consumption of disease-related resources...
2017: ClinicoEconomics and Outcomes Research: CEOR
https://www.readbyqxmd.com/read/28910690/smoking-cessation-for-substance-misusers-a-systematic-review-of-qualitative-studies-on-participant-and-provider-beliefs-and-perceptions
#15
REVIEW
Sarah Gentry, Jean Craig, Richard Holland, Caitlin Notley
INTRODUCTION: Smoking prevalence among those in substance misuse treatment remains much higher than the general population, despite evidence for effective cessation interventions that do not negatively impact substance misuse outcomes. This systematic review summarises qualitative data on barriers and facilitators to smoking cessation for people in substance misuse treatment, participants' and providers' perceptions about effects of smoking cessation on substance misuse treatment, timing of intervention delivery and aspects of interventions perceived to be effective...
September 1, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28903893/user-acceptance-of-computerized-cognitive-behavioral-therapy-for-depression-systematic-review
#16
Theresia Rost, Janine Stein, Margrit Löbner, Anette Kersting, Claudia Luck-Sikorski, Steffi G Riedel-Heller
BACKGROUND: Computerized cognitive behavioral therapy (cCBT) has been proven to be effective in depression care. Moreover, cCBT packages are becoming increasingly popular. A central aspect concerning the take-up and success of any treatment is its user acceptance. OBJECTIVE: The aim of this study was to update and expand on earlier work on user acceptance of cCBT for depression. METHODS: This paper systematically reviewed quantitative and qualitative studies regarding the user acceptance of cCBT for depression...
September 13, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/28890408/interventions-for-treating-3-or-4-part-proximal-humeral-fractures-in-elderly-patient-a-network-meta-analysis-of-randomized-controlled-trials
#17
REVIEW
Shaolong Du, Jiahao Ye, Haolong Chen, Xishan Li, Qiang Lin
BACKGROUND: The fractures of proximal humerus have a high incidence in elderly patients, especially 3- or 4-part fracture. There are 4 main treatments including nonoperation, open reduction and internal fixation(ORIF), hemiarthroplasty(HA) and reverse shoulder arthroplasty(RSA). However, which one is the optimal choice remains a controversial topic. METHODS: Through the search of three electronic databases (PubMed, Embase, and Cochrane), the randomized controlled trials of 3- or 4-part proximal humeral fracture, until the end of July 2017, which is concerned with the elderly patients, were identified...
September 7, 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/28886751/uva-ursi-extract-and-ibuprofen-as-alternative-treatments-of-adult-female-urinary-tract-infection-atafuti-study-protocol-for-a-randomised-controlled-trial
#18
Jeanne Trill, Catherine Simpson, Frances Webley, Mike Radford, Louise Stanton, Tom Maishman, Angeliki Galanopoulou, Andrew Flower, Caroline Eyles, Merlin Willcox, Alastair Hay, Gareth Griffiths, Paul Little, George Lewith, Michael Moore
BACKGROUND: Women with acute uncomplicated urine infection are usually treated with antibiotics. One trial has demonstrated that delayed antibiotic treatment offered without symptom relief results in a modest reduction in antibiotic use. There is some evidence that ibuprofen provides symptom relief and reduces antibiotic use. Uva-ursi, a herbal product, has a traditional use for urinary infection symptom relief. We set out to test: in adult women with suspected UTI who accept the delayed prescription strategy: Do NSAIDs or uva-ursi (a herbal product) provide relief from urinary symptoms and reduce antibiotic use...
September 8, 2017: Trials
https://www.readbyqxmd.com/read/28883783/performing-arm-based-network-meta-analysis-in-r-with-the-pcnetmeta-package
#19
Lifeng Lin, Jing Zhang, James S Hodges, Haitao Chu
Network meta-analysis is a powerful approach for synthesizing direct and indirect evidence about multiple treatment comparisons from a collection of independent studies. At present, the most widely used method in network meta-analysis is contrast-based, in which a baseline treatment needs to be specified in each study, and the analysis focuses on modeling relative treatment effects (typically log odds ratios). However, population-averaged treatment-specific parameters, such as absolute risks, cannot be estimated by this method without an external data source or a separate model for a reference treatment...
August 2017: Journal of Statistical Software
https://www.readbyqxmd.com/read/28874177/improving-diets-and-nutrition-through-an-integrated-poultry-value-chain-and-nutrition-intervention-selever-in-burkina-faso-study-protocol-for-a-randomized-trial
#20
Aulo Gelli, Elodie Becquey, Rasmane Ganaba, Derek Headey, Melissa Hidrobo, Lieven Huybregts, Hans Verhoef, Romain Kenfack, Sita Zongouri, Hannah Guedenet
BACKGROUND: The SELEVER study is designed to evaluate the impact of an integrated agriculture-nutrition package of interventions (including poultry value chain development, women's empowerment activities, and a behavior change communications strategy to promote improved diets and feeding, care, and hygiene practices) on the diets, health, and nutritional status of women and children in Burkina Faso. This paper presents the rationale and study design. METHODS: The impact evaluation involves a cluster randomized controlled trial design that will be implemented in 120 rural communities/villages within 60 communes supported by SELEVER in the Boucle de Mouhoun, Centre-Ouest, and Haut-Bassins regions of Burkina Faso...
September 6, 2017: Trials
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