keyword
MENU ▼
Read by QxMD icon Read
search

Treatment outcome package

keyword
https://www.readbyqxmd.com/read/29657903/obstructive-sleep-apnea-as-a-risk-factor-for-atrial-fibrillation-a-meta-analysis
#1
Irini Youssef, Haroon Kamran, Mena Yacoub, Nirav Patel, Clive Goulbourne, Shweta Kumar, Jesse Kane, Haley Hoffner, Moro Salifu, Samy I McFarlane
Objectives: To conducted a meta-analysis assessing the relationship between Obstructive Sleep Apnea (OSA) and the risk of Atrial Fibrillation (AF). Methods: We searched PUBMED, Medline, and Cochrane Library using the keywords "atrial fibrillation", "obstructive sleep apnea" and "sleep disordered breathing (SDB)". All subjects included had established diagnosis of OSA/SDB. We then compared the occurrence of AF versus no AF. Analysis done with Comprehensive Meta-Analysis package V3 (Biostat, USA)...
2018: Journal of Sleep Disorders & Therapy
https://www.readbyqxmd.com/read/29657199/impact-of-body-mass-index-on-progression-of-primary-immunoglobulin-a-nephropathy
#2
Shankar Prasad Nagaraju, Dharshan Rangaswamy, Aswani Srinivas Mareddy, Srikanth Prasad, Sindhu Kaza, Srinivas Shenoy, Karan Saraf, Ravindra Prabhu Attur, Rajeevalochana Parthasarathy, Srinivas Kosuru, Uday Venkat Mateti, Vasudeva Guddattu, Sindhura Lakshmi Koulmane Laxminarayana
The role of obesity in the progression of primary glomerular diseases is controversial. A few studies report overweight/obesity as a risk factor for disease progression in immunoglobulin A nephropathy (IgAN), and the real impact of it still remains unclear. The aim of this study was to elucidate the effect of body mass index (BMI) on disease progression and proteinuria in patients with IgAN in Indian population. A cohort of biopsy-proven primary IgAN patients diagnosed between March 2010 and February 2015 who had a follow-up for a minimum of 12 months were included in the study...
March 2018: Saudi Journal of Kidney Diseases and Transplantation
https://www.readbyqxmd.com/read/29614982/how-to-customize-a-bona-fide-psychotherapy-for-generalized-anxiety-disorder-a-two-arms-patient-blinded-abab-crossed-therapist-randomized-clinical-implementation-trial-design-implement-2-0
#3
Christoph Flückiger, Christine Wolfer, Judith Held, Peter Hilpert, Julian Rubel, Mathias Allemand, Richard E Zinbarg, Andreea Vîslă
BACKGROUND: Bona fide psychotherapy approaches are effective treatments for generalized anxiety disorder (GAD) compared to no-treatment conditions. Treatment manuals and protocols allow a relatively high degree of freedom for the way therapists implement these overall treatment packages and there is a systematic lack of knowledge on how therapists should customize these treatments. The present study experimentally examines two implementation strategies of customizing a bona fide psychotherapy approach based on a 16 session time-limited cognitive-behavioral therapy (CBT) protocol and their relation to the post-session and ultimate treatment outcomes...
April 3, 2018: BMC Psychiatry
https://www.readbyqxmd.com/read/29603139/a-direct-to-patient-telemedicine-abortion-service-in-australia-retrospective-analysis-of-the-first-18-months
#4
Paul Hyland, Elizabeth G Raymond, Erica Chong
BACKGROUND: In 2015, the Tabbot Foundation launched a nationwide direct-to-patient telemedicine service to enable women to obtain medical abortion without visiting an abortion provider. AIMS: We aimed to describe results from the first 18 months of this service. MATERIALS AND METHODS: To have an abortion through the Foundation, a woman obtained screening tests locally and had a telephone consultation with a Foundation doctor. If she was eligible, mifepristone, misoprostol and other medications were sent to her by mail...
March 30, 2018: Australian & New Zealand Journal of Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/29575339/treatment-response-and-non-response-in-cbt-and-network-support-for-alcohol-disorders-targeted-mechanisms-and-common-factors
#5
Mark D Litt, Ronald M Kadden, Howard Tennen
AIMS: To determine whether mechanisms of drinking behavior-change that are targeted by specific treatments mediate the effects of Packaged Cognitive-Behavior Therapy (PCBT) and Network Support (NS) on abstinence rates over 27 months. DESIGN: Secondary analysis of data from two Network Support Project randomized clinical trials (1, 2), in which participants were assigned to either a case management control treatment (Control) or NS treatment in trial 1, or to PCBT or NS Treatment in trial 2...
March 25, 2018: Addiction
https://www.readbyqxmd.com/read/29564164/rpsftm-an-r-package-for-rank-preserving-structural-failure-time-models
#6
Annabel Allison, Ian R White, Simon Bond
Treatment switching in a randomised controlled trial occurs when participants change from their randomised treatment to the other trial treatment during the study. Failure to account for treatment switching in the analysis (i.e. by performing a standard intention-to-treat analysis) can lead to biased estimates of treatment efficacy. The rank preserving structural failure time model (RPSFTM) is a method used to adjust for treatment switching in trials with survival outcomes. The RPSFTM is due to Robins and Tsiatis (1991) and has been developed by White et al...
December 4, 2017: R Journal
https://www.readbyqxmd.com/read/29557705/global-sensitivity-analysis-of-clinical-trials-with-missing-patient-reported-outcomes
#7
Daniel O Scharfstein, Aidan McDermott
Randomized trials with patient-reported outcomes are commonly plagued by missing data. The analysis of such trials relies on untestable assumptions about the missing data mechanism. To address this issue, it has been recommended that the sensitivity of the trial results to assumptions should be a mandatory reporting requirement. In this paper, we discuss a recently developed methodology (Scharfstein et al., Biometrics, 2018) for conducting sensitivity analysis of randomized trials in which outcomes are scheduled to be measured at fixed points in time after randomization and some subjects prematurely withdraw from study participation...
January 1, 2018: Statistical Methods in Medical Research
https://www.readbyqxmd.com/read/29556133/quality-of-life-and-complementary-and-alternative-medicine-use-among-women-with-breast-cancer
#8
Hadeel Albabtain, Monira Alwhaibi, Khalid Alburaikan, Yousif Asiri
Background: Complementary and Alternative Medication (CAM) is commonly used among women with breast cancer to improve their quality of life (QoL). However, few studies examine the prevalence of CAM and its' relation to the patients' QoL among women with breast cancer. Methods: A cross-sectional study was conducted among 95 women with breast cancer at a tertiary hospital in Saudi Arabia. The outcome measure of interest was the QoL. The correlation was used to assess the association between CAM use and QoL...
March 2018: Saudi Pharmaceutical Journal: SPJ: the Official Publication of the Saudi Pharmaceutical Society
https://www.readbyqxmd.com/read/29527754/the-coping-with-unusual-experiences-for-children-study-cues-a-pilot-randomized-controlled-evaluation-of-the-acceptability-and-potential-clinical-utility-of-a-cognitive-behavioural-intervention-package-for-young-people-aged-8-14-years-with-unusual-experiences
#9
Suzanne Jolley, Elizabeth Kuipers, Catherine Stewart, Sophie Browning, Karen Bracegirdle, Nedah Basit, Kimberley Gin, Colette Hirsch, Richard Corrigall, Partha Banerjea, Grainne Turley, Daniel Stahl, Kristin R Laurens
OBJECTIVES: Health care guidelines recommend psychological interventions for childhood unusual experiences that are associated with distress or adverse functional impact (UEDs), based on adult, rather than child-specific, evidence. We report the first randomized controlled evaluation of the acceptability and potential clinical utility of cognitive behavioural therapy for childhood UEDs (CBT-UED). DESIGN: Pilot randomized controlled trial. METHODS: Participants aged 8-14 years were recruited from referrals to community services for children with emotional/behavioural problems and screened for self-reported UEDs...
March 12, 2018: British Journal of Clinical Psychology
https://www.readbyqxmd.com/read/29514327/how-do-uk-physical-therapists-manage-patients-with-hip-osteoarthritis-results-of-a-cross-sectional-survey
#10
Melanie A Holden, Kim L Bennell, Rebecca Whittle, Linda Chesterton, Nadine E Foster, Nicola A Halliday, Libby N Spiers, Elizabeth M Mason, Jonathan G Quicke, Christian D Mallen
Background: Hip osteoarthritis (OA) is common, painful and disabling. Physical therapists have an important role in managing patients with hip OA, however little is known about their current management approach and whether it aligns with clinical guideline recommendations. Objective: The objective of this study is to describe UK physical therapists' current management of patients with hip OA and to determine whether it aligns with clinical guidelines. Design: The design is a cross-section questionnaire...
March 4, 2018: Physical Therapy
https://www.readbyqxmd.com/read/29488830/translating-evidence-based-practice-for-managing-comorbid-substance-use-and-mental-illness-using-a-multi-modal-training-package
#11
Eva Louie, Vicki Giannopoulos, Andrew Baillie, Gabriela Uribe, Simon Byrne, Mark Deady, Maree Teesson, Amanda Baker, Paul S Haber, Kirsten C Morley
Comorbid mental health and substance use problems are highly prevalent in substance use treatment settings and generally lead to poorer treatment outcomes. Pathways to Comorbidity Care (PCC) is a multi-modal training program developed to encourage an integrated service approach to improve clinicians' capacity to identify and manage comorbid substance use and mental health outcomes within public drug and alcohol treatment settings. In this paper we describe the concepts underlying the PCC Package and the use of Implementation Science to assess and overcome potential barriers, including clinicians' preferences, knowledge about best practice and professional culture...
February 28, 2018: Journal of Dual Diagnosis
https://www.readbyqxmd.com/read/29486790/effect-of-an-integrated-intervention-package-of-preventive-chemotherapy-community-led-total-sanitation-and-health-education-on-the-prevalence-of-helminth-and-intestinal-protozoa-infections-in-c%C3%A3-te-d-ivoire
#12
Eveline Hürlimann, Kigbafori D Silué, Fabien Zouzou, Mamadou Ouattara, Thomas Schmidlin, Richard B Yapi, Clarisse A Houngbedji, Kouassi Dongo, Bernadette A Kouadio, Siaka Koné, Bassirou Bonfoh, Eliézer K N'Goran, Jürg Utzinger, Cinthia A Acka-Douabélé, Giovanna Raso
BACKGROUND: Preventive chemotherapy with donated anthelminthic drugs is the cornerstone for the control of helminthiases. However, reinfection can occur rapidly in the absence of clean water and sanitation coupled with unhygienic behaviour. The purpose of this study was to assess the effect of an integrated package of interventions, consisting of preventive chemotherapy, community-led total sanitation (CLTS) and health education, on the prevalence of helminth and intestinal protozoa infections and on participants' knowledge, attitude, practice and beliefs (KAPB) towards these diseases including water, sanitation and hygiene (WASH)...
February 27, 2018: Parasites & Vectors
https://www.readbyqxmd.com/read/29472099/neurotransmitter-activity-is-linked-to-outcome-following-subthalamic-deep-brain-stimulation-in-parkinson-s-disease
#13
Ruth L O'Gorman Tuura, Christian R Baumann, Heide Baumann-Vogel
INTRODUCTION: While the mechanisms underlying the therapeutic effects of deep brain stimulation (DBS) in Parkinson's Disease (PD) are not yet fully understood, DBS appears to exert a wide range of neurochemical effects on the network level, thought to arise from activation of inhibitory and excitatory pathways. The activity within the primary inhibitory (GABAergic) and excitatory (glutamatergic) neurotransmitter systems may therefore play an important role in the therapeutic efficacy of DBS in PD...
February 8, 2018: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/29470731/sacral-neuromodulation-versus-personalized-conservative-treatment-in-patients-with-idiopathic-slow-transit-constipation-study-protocol-of-the-no-2-trial-a-multicenter-open-label-randomized-controlled-trial-and-cost-effectiveness-analysis
#14
S C M Heemskerk, A H Rotteveel, M A Benninga, C I M Baeten, A A M Masclee, J Melenhorst, S M J van Kuijk, C D Dirksen, S O Breukink
PURPOSE: The evidence regarding the (cost-)effectiveness of sacral neuromodulation (SNM) in patients with therapy-resistant idiopathic slow-transit constipation is of suboptimal quality. The Dutch Ministry of Health, Welfare and Sports has granted conditional reimbursement for SNM treatment. The objective is to assess the effectiveness, cost-effectiveness, and budget impact of SNM compared to personalized conservative treatment (PCT) in patients with idiopathic slow-transit constipation refractory to conservative treatment...
February 22, 2018: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/29466415/revisiting-policy-on-chronic-hcv-treatment-under-the-thai-universal-health-coverage-an-economic-evaluation-and-budget-impact-analysis
#15
Waranya Rattanavipapong, Thunyarat Anothaisintawee, Yot Teerawattananon
Thailand is encountering challenges to introduce the high-cost sofosbuvir for chronic hepatitis C treatment as part of the Universal Health Care's benefit package. This study was conducted in respond to policy demand from the Thai government to assess the value for money and budget impact of introducing sofosbuvir-based regimens in the tax-based health insurance scheme. The Markov model was constructed to assess costs and benefits of the four treatment options that include: (i) current practice-peginterferon alfa (PEG) and ribavirin (RBV) for 24 weeks in genotype 3 and 48 weeks for other genotypes; (ii) Sofosbuvir plus peginterferon alfa and ribavirin (SOF+PEG-RBV) for 12 weeks; (iii) Sofosbuvir and daclatasvir (SOF+DCV) for 12 weeks; (iv) Sofosbuvir and ledipasvir (SOF+LDV) for 12 weeks for non-3 genotypes and SOF+PEG-RBV for 12 weeks for genotype 3 infection...
2018: PloS One
https://www.readbyqxmd.com/read/29460383/using-permutation-tests-to-enhance-causal-inference-in-interrupted-time-series-analysis
#16
Ariel Linden
RATIONALE, AIMS AND OBJECTIVES: Interrupted time series analysis (ITSA) is an evaluation methodology in which a single treatment unit's outcome is studied serially over time and the intervention is expected to "interrupt" the level and/or trend of that outcome. The internal validity is strengthened considerably when the treated unit is contrasted with a comparable control group. In this paper, we introduce a robustness check based on permutation tests to further improve causal inference...
February 20, 2018: Journal of Evaluation in Clinical Practice
https://www.readbyqxmd.com/read/29427992/apple-condom-and-cocaine-body-stuffing-in-prison-a-case-report
#17
Benedicte Jalbert, Nguyen Toan Tran, Stephan von Düring, Pierre-Alexandre Poletti, Ian Fournier, Catherine Hafner, Celestine Dubost, Laurent Gétaz, Hans Wolff
BACKGROUND: Drug dealers and drug users resort to body stuffing to hastily conceal illicit drugs by ingesting their drug packets. This practice represents a medical challenge because rupture of the often insecure packaging can be toxic and even lethal. In an emergency setting, official guidelines are needed to help the medical team decide on the proper treatment. A preliminary observation period is generally accepted but its duration varies from hours to eventual packet expulsion. CASE PRESENTATION: This case involves a 20-year-old white man in detention who claimed to have ingested one cocaine packet wrapped in plastic food-wrap and a condom in anticipation of an impending cell search...
February 11, 2018: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/29419623/clinical-effectiveness-of-decongestive-treatments-on-excess-arm-volume-and-patient-centered-outcomes-in-women-with-early-breast-cancer-related-arm-lymphedema-a-systematic-review
#18
Eunice Jeffs, Emma Ream, Cath Taylor, Debra Bick
OBJECTIVE: To identify the effect of decongestive lymphedema treatment on excess arm volume or patient-centered outcomes in women presenting within either 12 months or a mean nine months of developing arm lymphedema following breast cancer treatment. INTRODUCTION: Lymphedema is a common consequence of breast cancer treatment requiring life-long treatment to reduce symptoms and prevent complications. Currently, evidence to inform the optimal decongestive lymphedema treatment package is lacking...
February 2018: JBI Database of Systematic Reviews and Implementation Reports
https://www.readbyqxmd.com/read/29419605/ceftaroline-for-suspected-or-confirmed-invasive-methicillin-resistant-staphylococcus-aureus-a-pharmacokinetic-case-series
#19
Jeffrey J Cies, Wayne S Moore, Adela Enache, Arun Chopra
OBJECTIVES: To describe the ceftaroline pharmacokinetics in critically ill children treated for suspected or confirmed methicillin-resistant Staphylococcus aureus infections, including blood stream infection and describe the microbiological and clinical outcomes. DESIGN: Retrospective electronic medical record review. SETTINGS: Free-standing tertiary/quaternary pediatric children's hospital. PATIENTS: Critically ill children receiving ceftaroline monotherapy or combination therapy for suspected or confirmed methicillin-resistant S...
February 6, 2018: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/29394465/national-disparities-in-treatment-package-time-for-resected-locally-advanced-head-and-neck-cancer-and-impact-on-overall-survival
#20
David M Guttmann, Julie Kobie, Surbhi Grover, Alexander Lin, John N Lukens, Nandita Mitra, Karin V Rhodes, Weiwei Feng, Samuel Swisher-McClure
BACKGROUND: The purpose of this study was to determine national disparities in head and neck cancer treatment package time (the time interval from surgery through the completion of radiation) and the associated impact on survival. METHODS: We conducted an observational cohort study using the National Cancer Database of 15 234 patients with resected head and neck cancer who underwent adjuvant radiotherapy from 2004-2012. Predictors of prolonged package time were identified by multivariable linear regression...
February 2, 2018: Head & Neck
keyword
keyword
119328
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"