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https://www.readbyqxmd.com/read/29052825/managing-endoscopic-retrograde-cholangiopancreatography-related-complications-in-patients-referred-to-the-surgical-emergency-unit
#1
Osman Şimşek, Arife Şimşek, Sefa Ergun, Mehmet Velidedeoğlu, Kaya Sarıbeyoğlu, Salih Pekmezci
BACKGROUND: The goal of this study was to present our experience in the management of endoscopic retrograde cholangiopancreatography-related complications in patients referred to our surgical emergency unit by various endoscopy centers. METHODS: A retrospective investigation was conducted on the records of the 54 patients who were referred to our surgical emergency unit between October 2005 and January 2014 due to endoscopic retrograde cholangiopancreatography-related complications...
September 2017: Ulusal Travma Ve Acil Cerrahi Dergisi, Turkish Journal of Trauma & Emergency Surgery: TJTES
https://www.readbyqxmd.com/read/29049933/systemic-autoimmune-diseases-are-associated-with-an-increased-risk-of-bipolar-disorder-a-nationwide-population-based-cohort-study
#2
Ling-Yi Wang, Jen-Huai Chiang, Shih-Fen Chen, Yu-Chih Shen
BACKGROUND: Studies suggested autoimmunity plays a role in the etiology of bipolar disorder (BD). This study aimed to investigate the association between systemic autoimmune diseases (SADs) and the subsequent development of BD, and examine the potential risk factors for developing BD. METHODS: Patients with SADs were identified in the Taiwan National Health Insurance Program (NHIP). A comparison cohort was created by matching patients without SADs with age. The SADs cohort consisted of 65,498 while the comparison cohort consisted of 261,992 patients...
October 7, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29049232/case-report-central-nervous-system-involvement-of-human-graft-versus-host-disease-report-of-7-cases-and-a-review-of-literature
#3
Mathilde Ruggiu, Wendy Cuccuini, Karima Mokhtari, Véronique Meignin, Régis Peffault de Latour, Marie Robin, Flore Sicre de Fontbrune, Aliénor Xhaard, Gérard Socié, David Michonneau
RATIONALE: Central nervous system (CNS) involvement of graft versus host disease (GvHD) is a rare cause of CNS disorders after allogeneic hematopoietic stem cell transplantation (allo-HSCT). Chronic CNS GvHD symptoms are heterogeneous and include cerebrovascular manifestations, demyelinating disease and immune-mediated encephalitis. CNS-Acute GvHD is not formally defined in literature. PATIENTS CONCERNS AND DIAGNOSES: We report 7 cases of CNS-GvHD among which two had histological-proven disease...
October 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29046727/elevated-circulating-fasting-glucagon-like-peptide-1-in-surgical-patients-with-aortic-valve-disease-and-diabetes
#4
Camilla Krizhanovskii, Stelia Ntika, Christian Olsson, Per Eriksson, Anders Franco-Cereceda
BACKGROUND: Diabetes is a risk factor for peripheral, coronary, and cerebrovascular disease. In contrast, results also indicate that patients with diabetes have reduced prevalence of aortic aneurysms, although the mechanisms remain largely unknown. We hypothesize that altered endogenous secretion of the intestinal hormone glucagon-like peptide-1 (GLP-1)-previously shown to protect from aneurysm formation, and governing many of the mechanisms thought to be involved in aneurysm formation-may provide insights into the mechanisms underlying the inverse relationship of diabetes and aneurysm...
2017: Diabetology & Metabolic Syndrome
https://www.readbyqxmd.com/read/29046320/mortality-and-cerebrovascular-events-following-heart-rhythm-disorder-management-procedures
#5
Justin Z Lee, Jayna Ling, Nancy N Diehl, David O Hodge, Deepak Padmanabhan, Ammar M Killu, Malini Madhavan, Peter A Noseworthy, Suraj Kapa, Christopher J McLeod, Yong-Mei Cha, Abhishek J Deshmukh, Komandoor Srivathsan, Fred M Kusumoto, Win-Kuang Shen, Paul A Friedman, Thomas M Munger, Samuel J Asirvatham, Douglas L Packer, Siva K Mulpuru
Background -Recognition of rates and causes of hard, patient-centered outcomes of death and cerebrovascular event (CVE) after heart rhythm disorder management (HRDM) procedures is an essential step for development of quality improvement programs in electrophysiology laboratories. Our primary aim was to assess and characterize death and CVE (stroke or transient ischemic attack) after HRDM procedures over a 17-year period. Methods -We performed a retrospective cohort study of all patients undergoing HRDM procedures between January 2000 and November 2016 at the Mayo Clinic...
October 18, 2017: Circulation
https://www.readbyqxmd.com/read/29042934/intermittent-hypoxia-simulating-obstructive-sleep-apnea-causes-pulmonary-inflammation-and-activates-the-nrf2-ho-1-pathway
#6
Yeying Wang, Yanling Chai, Xiaojie He, Li Ai, Xia Sun, Yiling Huang, Yongxia Li
Obstructive sleep apnea (OSA) is a disorder with high morbidity in adults. OSA damages multiple organs and tissues, including the cardiovascular and cerebrovascular systems, the metabolism system, the lungs, liver and heart. OSA-induced damage is earliest and greatest to the pulmonary tissue. The present study established a rat OSA model of differing severity by inducing intermittent hypoxia with different concentrations of O2 and it was determined that OSA caused a severe oxidative stress response and pulmonary inflammation in a dose-dependent manner...
October 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29037336/neuropsychiatry-towards-a-philosophy-of-praxis
#7
Jesús Ramirez-Bermudez, Rodrigo Perez-Esparza, Luis Carlos Aguilar-Venegas, Perminder Sachdev
Neuropsychiatry is a specialized clinical, academic and scientific discipline with its field located in the borderland territory between neurology and psychiatry. In this article, we approach the theoretical definition of neuropsychiatry, and in order to address the practical aspects of the discipline, we describe the profile of a neuropsychiatric liaison service in the setting of a large hospital for neurological diseases in a middle-income country. An audit of consecutive in-patients requiring neuropsychiatric assessment at the National Institute of Neurology and Neurosurgery of Mexico is reported, comprising a total of 1212 patients...
October 2017: Revista Colombiana de Psiquiatría
https://www.readbyqxmd.com/read/29033830/the-decrease-of-uch-l1-activity-is-a-common-mechanism-responsible-for-a%C3%AE-42-accumulation-in-alzheimer-s-and-vascular-disease
#8
Michela Guglielmotto, Debora Monteleone, Valeria Vasciaveo, Ivan Enrico Repetto, Giusi Manassero, Massimo Tabaton, Elena Tamagno
Alzheimer's disease (AD) is a multifactorial pathology causing common brain spectrum disorders in affected patients. These mixed neurological disorders not only include structural AD brain changes but also cerebrovascular lesions. The main aim of the present issue is to find the factors shared by the two pathologies. The decrease of ubiquitin C-terminal hydrolase L1 (Uch-L1), a major neuronal enzyme involved in the elimination of misfolded proteins, was observed in ischemic injury as well as in AD, but its role in the pathogenesis of AD is far to be clear...
2017: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/29021415/cerebrovascular-cardiovascular-diseases-and-mental-disorders-due-to-overwork-and-work-related-stress-among-local-public-employees-in-japan
#9
Takashi Yamauchi, Toru Yoshikawa, Takeshi Sasaki, Shun Matsumoto, Masaya Takahashi, Machi Suka, Hiroyuki Yanagisawa
In Japan, overwork-related disorders occur among local public employees as well as those in private businesses. However, to date, there are no studies reporting the state of compensation for cerebrovascular/cardiovascular diseases (CCVD) and mental disorders due to overwork or work-related stress among local public employees in Japan over multiple years. This report examined the recent trend of overwork-related CCVD and mental disorders, including the incidence rates of these disorders, among local public employees in Japan from the perspective of compensation for public accidents, using data from the Japanese Government and relevant organizations...
October 11, 2017: Industrial Health
https://www.readbyqxmd.com/read/29018399/therapeutic-interventions-for-vascular-parkinsonism-a-systematic-review-and-meta-analysis
#10
Adán Miguel-Puga, Gabriel Villafuerte, José Salas-Pacheco, Oscar Arias-Carrión
BACKGROUND: Vascular parkinsonism (VP) is defined as the presence of parkinsonian syndrome, evidence of cerebrovascular disease, and an established relationship between the two disorders. However, the diagnosis of VP is problematic, particularly for the clinician confronted with moving from diagnosis to treatment. Given the different criteria used in the diagnosis of VP, the effectiveness of available therapeutic interventions for this disease are currently unknown. METHODS: To assess the clinical response of all published therapeutic interventions for VP that have been reported in the literature, we conducted a systematic review looking for VP subjects treated with any therapeutic intervention...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28988884/cerebral-hyperperfusion-syndrome-an-unusual-but-disastrous-complication-of-carotid-recanalization-a-case-report
#11
Bahaadin Siroos, Mohammad Hossein Harirchian, Ali Kazemi Khaledi, Majid Ghaffarpour, Samad Golshani
Cerebral hyperperfusion syndrome (CHS), known as the dark side of carotid recanalization, happens in about 0%-3% of patients. Unfortunately, physicians involving in carotid recanalization generally are not aware of diagnostic and therapeutic aspects of this unusual but potentially life-threatening disorder. Severe bilateral carotid stenosis is suggested to predispose patients to CHS by decrement of cerebrovascular reactivity in a setting of chronic hypoperfusion state. We here introduced such a case; a 69-year-old man, a known case of hypertension and ischemic heart disease, who developed progressive intracranial hypertension underlying CHS after carotid stenting because of symptomatic severe bilateral carotid stenosis...
October 5, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28987197/neuropathology-of-cerebrovascular-diseases
#12
Isidro Ferrer, Noemi Vidal
The chapter describes the epidemiology of cerebrovascular diseases, anatomy of the cerebral blood vessels, pathophysiology of ischemia, hypoxia, hypoxemia, anemic hypoxia, histotoxic hypoxia, carbon monoxide damage, hyperoxid brain damage and decompression sickness, and selective cell and regional vulnerability; diseases of the blood vessels including atherosclerosis, hypertensive angiopathy, small vessel disease, inflammatory vascular diseases, cerebral amyloid angiopathies, CADASIL, CARASIL and other diseases that can lead to cerebrovascular occlusion; intracranial and intraspinal aneurysms and vascular malformations; hematologic disorders that can cause cerebral infarct or hemorrhage; brain ischemic damage; and spontaneous intracranial bleeding...
2017: Handbook of Clinical Neurology
https://www.readbyqxmd.com/read/28984599/sleep-apnea-cognitive-profile-and%C3%A2-vascular-changes-an-intriguing-relationship
#13
Laura Buratti, Giovanna Viticchi, Sara Baldinelli, Lorenzo Falsetti, Simona Luzzi, Alessandra Pulcini, Cristina Petrelli, Leandro Provinciali, Mauro Silvestrini
BACKGROUND: Sleep breathing disorders can affect cognitive performances through complex brain anatomical and functional changes. OBJECTIVE: Our aim was to evaluate the correlations between cognitive performances and obstructive sleep apnea syndrome (OSAS), as well as the possible influence of vascular factors. METHODS: Thirty-four non-demented OSAS patients and 34 controls were submitted to a neuropsychological evaluation and to a vascular screening including the study of cerebrovascular reactivity by means of the breath-holding index (BHI) calculation...
2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28984145/central-nervous-system-complications-after-allogeneic-hematopoietic-stem-cell-transplantation
#14
Ranjit Kumar Chaudhary, Prajwal Dhakal, Aashrayata Aryal, Vijaya Raj Bhatt
Allogenic hematopoietic stem cell transplant (alloSCT) is a potentially curative modality of treatment for patients with hematological malignancies. However, CNS complications following transplant pose a risk to survival of the patients. Early recognition and management of these complications are crucial to reduce morbidity and mortality of patients following transplant. Early CNS complications associated with alloSCT are infection, cerebrovascular events, chemotherapy and radiation-induced toxicities while late complications include post-transplant lymphoproliferative disorder, CNS relapse of underlying malignancy and viral and fungal infections...
October 6, 2017: Future Oncology
https://www.readbyqxmd.com/read/28981541/contrasting-resting-state-fmri-abnormalities-from-sickle-and-non-sickle-anemia
#15
Julie Coloigner, Yeun Kim, Adam Bush, Soyoung Choi, Melissa C Balderrama, Thomas D Coates, Sharon H O'Neil, Natasha Lepore, John C Wood
Sickle cell disease (SCD) is a chronic blood disorder that is often associated with acute and chronic cerebrovascular complications, including strokes and impaired cognition. Using functional resting state magnetic resonance images, we performed whole-brain analysis of the amplitude of low frequency fluctuations (ALFF), to detect areas of spontaneous blood oxygenation level dependent signal across brain regions. We compared the ALFF of 20 SCD patients to that observed in 19 healthy, age and ethnicity-matched, control subjects...
2017: PloS One
https://www.readbyqxmd.com/read/28980585/-modern-approaches-to-neuroprotective-treatment-of-ischemic-stroke
#16
L V Stakhovskaya, E A Tyutyumova, A I Fedin
The authors present the results of domestic clinical trials on the efficacy and safety of mexidol in patients with cerebrovascular disorders including ischemic stroke (IS). The use of mexidol is associated with complete and rapid regression of the focal neurological deficit. Mexidol is well tolerated with no significant side-effects. The drug is recommended for enteral and parenteral administration in patients with IS.
2017: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/28979573/prosthodontic-rehabilitation-of-arabic-speaking-individuals-with-velopharyngeal-incompetence-a-preliminary-study
#17
Abdel Rahim M Bibars, Firas S D Alfwaress, Abed Al-Hadi Hamasha, Zeid A Al-Hourani, Khader Almhdawi
BACKGROUND: Hypernasality is a frequently encountered problem in the speech of individuals with velopharyngeal incompetence. The use of palatal lift appliance (PLA) is the main treatment option for correction of velopharyngeal incompetence. The literature on the outcomes of using prosthetics treatment for Arabic speaking patients is scarce. OBJECTIVE: The aim of this study was to investigate the effect of using PLA on hypernasality of Arabic speaking patients with velopharyngeal incompetence...
2017: Open Dentistry Journal
https://www.readbyqxmd.com/read/28969391/migraine-and-risk-of-stroke-a-national-population-based-twin-study
#18
Maria Lantz, Johanna Sieurin, Arvid Sjölander, Elisabet Waldenlind, Christina Sjöstrand, Karin Wirdefeldt
Numerous studies have indicated an increased risk for stroke in patients with migraine, especially migraine with aura; however, many studies used self-reported migraine and only a few controlled for familial factors. We aimed to investigate migraine as a risk factor for stroke in a Swedish population-based twin cohort, and whether familial factors contribute to an increased risk. The study population included twins without prior cerebrovascular disease who answered a headache questionnaire during 1998 and 2002 for twins born 1935-58 and during 2005-06 for twins born between 1959 and 1985...
October 1, 2017: Brain: a Journal of Neurology
https://www.readbyqxmd.com/read/28962815/neurologic-complications-of-solid-organ-transplantation
#19
REVIEW
Michael Pizzi, Lauren Ng
Among patients receiving solid organ transplants, approximately one-third will develop neurologic symptoms. Most of these neurologic symptoms will occur within 30 days of their transplantation. These neurologic symptoms include neurotoxicity of immunosuppressive agents, seizures, encephalopathy, cerebrovascular events, opportunistic infections, posttransplant lymphoproliferative disorder, and central pontine myelinosis. Some neurologic complications are seen more frequently in specific organ transplant recipients...
November 2017: Neurologic Clinics
https://www.readbyqxmd.com/read/28957666/the-neurovascular-unit-coming-of-age-a-journey-through-neurovascular-coupling-in-health-and-disease
#20
REVIEW
Costantino Iadecola
The concept of the neurovascular unit (NVU), formalized at the 2001 Stroke Progress Review Group meeting of the National Institute of Neurological Disorders and Stroke, emphasizes the intimate relationship between the brain and its vessels. Since then, the NVU has attracted the interest of the neuroscience community, resulting in considerable advances in the field. Here the current state of knowledge of the NVU will be assessed, focusing on one of its most vital roles: the coupling between neural activity and blood flow...
September 27, 2017: Neuron
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