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https://www.readbyqxmd.com/read/29166764/merkel-cell-carcinoma-metastatic-to-pleural-fluid-a-case-report
#1
Ye-Young Rhee, Soo Hee Kim, Eun Kyung Kim, Se Hoon Kim
Merkel cell carcinoma (MCC) is a rare aggressive neuroendocrine carcinoma of the skin that shows locoregional and distant metastasis. Metastasis of MCC to body cavity effusion is extremely rare; only three cases had been reported so far. Metastatic MCC in effusion cytology shows small blue round cells with fine stippled chromatin like other small blue round cell tumors such as small cell lung carcinoma or lymphoma. The diagnosis of metastatic MCC could give patients good chances to get recently advanced therapeutic options...
November 23, 2017: Journal of Pathology and Translational Medicine
https://www.readbyqxmd.com/read/29166747/-primary-intestinal-lymphangiectasia-associated-with-follicular-lymphoma-one-case-report
#2
Y Y Wu, X Lai
No abstract text is available yet for this article.
October 14, 2017: Zhonghua Xue Ye Xue za Zhi, Zhonghua Xueyexue Zazhi
https://www.readbyqxmd.com/read/29166743/-extranodal-marginal-zone-lymphoma-of-bronchus-associate-lymphoid-tissue-a-case-report-and-literatures-review
#3
Y P Zhang, L Wang, L Cao, R N Lu, W Xu, J Y Li
No abstract text is available yet for this article.
October 14, 2017: Zhonghua Xue Ye Xue za Zhi, Zhonghua Xueyexue Zazhi
https://www.readbyqxmd.com/read/29166737/-clinical-analysis-of-patients-with-hemophagocytic-lymphohistiocytosis-complicated-with-gastrointestinal-bleeding
#4
Z L Jin, Y N Wang, Z Wang
Objective: To explore the clinical features of patients with hemophagocytic lymphohistiocytosis (HLH) complicated with gastrointestinal bleeding. Methods: The clinical data of 52 patients with HLH diagnosed from January 2015 to February 2017 were analyzed retrospectively. Results: ①Of the 52 patients[including 36 cases of EBV related (69.2%) , 5 cases of lymphoma related (9.6%) , 3 cases of primary HLH (5.8%) , 3 cases of rheumatism related (5.8%) , 2 cases of tuberculosis related (3.8%) , 3 cases of unknown causes (3...
October 14, 2017: Zhonghua Xue Ye Xue za Zhi, Zhonghua Xueyexue Zazhi
https://www.readbyqxmd.com/read/29166735/-the-specific-cytotoxicities-of-chimeric-antigen-receptor-engineered-t-cells-on-different-lymphomas
#5
R Zhang, Q Deng, S N Sui, X Jin, M F Zhao
Objective: To investigate the specific cytotoxicities of the second and third generations of chimeric antigen receptor (CAR) -engineered T cells (CAR-T) on different lymphomas. Methods: CAR-Ts were prepared by lentivirus packaging and infection of T cells. CCK-8, ELISA and Lactate dehydrogenase cytotoxicity assay were applied to detect the proliferation capacity, the secretion level of inflammatory factor and the specific cytotoxicity. Flow cytometry assay showed the specific cytotoxicity and residual level of CAR-T in lymphomas of treated mice...
October 14, 2017: Zhonghua Xue Ye Xue za Zhi, Zhonghua Xueyexue Zazhi
https://www.readbyqxmd.com/read/29166732/-application-of-pegylated-recombinant-human-granulocyte-colony-stimulating-factor-to-prevent-chemotherapy-induced-neutropenia-in-patients-with-lymphoma-a-prospective-multicenter-open-label-clinical-trial
#6
H Q Huang, B Bai, Y H Gao, D H Zou, S H Zou, H Tan, Y P Song, Z Y Li, J Jin, W Li, H Su, Y P Gong, M Z Zhong, Y R Shuang, J Zhu, J Q Zhang, Z Cai, Q L Teng, W J Sun, Y Yang, Z J Xia, H L Chen, L M Hua, Y Y Bao, N Wu
Objective: To evaluate the efficacy and safety of pegylated recombinant human granulocyte colony-stimulating factor (PEG-rhG-CSF) in prophylaxis neutropenia after chemotherapy in patients with lymphoma. Methods: This was a multicenter, single arm, open, phase Ⅳ clinical trial. Included 410 patients with lymphoma received multiple cycles of chemotherapy and PEG-rhG-CSF was administrated as prophylactic. The primary endpoint was the incidence of Ⅲ/Ⅳ grade neutropenia and febrile neutropenia (FN) after each chemotherapy cycle...
October 14, 2017: Zhonghua Xue Ye Xue za Zhi, Zhonghua Xueyexue Zazhi
https://www.readbyqxmd.com/read/29166635/the-protean-neuropsychiatric-and-vestibuloauditory-manifestations-of-neurosarcoidosis
#7
Jacqueline J Greene, Ilka C Naumann, Janet M Poulik, Kevin T Nella, Lindsay Weberling, Jeffrey P Harris, Akihiro J Matsuoka
BACKGROUND: A rare subset of sarcoidosis, neurosarcoidosis, is reported to occur in 5-7% of sarcoid patients and can manifest in a variety of ways. The most common are facial paralysis and optic neuritis, less commonly causing cochleovestibulopathy, blindness, anosmia, and other cranial nerve (CN) palsies. The sensory deficit may be severe and psychiatric symptoms may result from the effects of the disease or steroid treatment. Although MRI-compatible cochlear implants are now available, concerns about the feasibility of recoverable hearing with cochlear implantation in these patients as well as the practical difficulty of disease monitoring due to implant artifact must be considered...
November 23, 2017: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/29166521/case-for-diagnosis-systemic-light-chain-amyloidosis-with-cutaneous-involvement
#8
João Renato Vianna Gontijo, Jackson Machado Pinto, Maysa Carla de Paula
Systemic light chain amiloydosis is a rare disease. Due to its typical cutaneous lesions, dermatologists play an essential role in its diagnosis. Clinical manifestations vary according to the affected organ and are often unspecific. Definitive diagnosis is achieved through biopsy. We report a patient with palpebral amyloidosis, typical bilateral ecchymoses and cardiac involvement, without plasma cell dyscrasia or lymphomas. The patient died shortly after the diagnosis.
September 2017: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/29166511/primary-cutaneous-follicle-center-lymphoma
#9
Eline Pinheiro Weba Costa, Bethänia Dias de Lucena, Gabriela Athayde Amin, Maraya de Jesus Semblano Bittencourt, Leonidas Braga Dias, Carla Andréa Avelar Pires
Cutaneous lymphomas are classified according to their cellular origin into T-cell lymphoma and B-cell lymphoma. The annual incidence rate is 0.3 per 100,000 population. We report a case of a 56-year-old male patient who presented with a two-month history of nodules of varying sizes, some ulcerated, on the face, abdomen, and upper limbs. Histopathological examination and immunohistochemical study confirmed the diagnosis of primary cutaneous centrofollicular lymphoma. Studies have shown an increased incidence of non-Hodgkin lymphomas in the last decade...
September 2017: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/29166509/granulomatous-slack-skin-a-rare-subtype-of-mycosis-fungoides
#10
Letícia Marra da Motta, Cleverson Teixeira Soares, Sadamitsu Nakandakari, Gardênia Viana da Silva, Maria Helena Mazzi Freire Nigro, Leticia Stella Gardini Brandão
We report a case of granulomatous slack skin, a rare and indolent subtype of mycosis fungoides. It affects mainly men between the third and fourth decades. It is characterized by hardened and erithematous plaques that mainly affect flexural areas and become pedunculated after some years. Histological examination shows a dense infiltrate of small atypical lymphocytes involving the dermis (and sometimes the subcutaneous tissue) associated with histiocytic and multinucleated giant cells containing lymphocytes and elastic fibers (lymphophagocytosis and elastophagocytosis, respectively)...
September 2017: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/29166501/primary-cutaneous-t-cell-lymphoma-experience-from-the-peruvian-national-cancer-institute
#11
Rosana Ruiz, Zaida Morante, Raul Mantilla, Luis Mas, Luis Casanova, Henry L Gomez
BACKGROUND: Primary cutaneous T-cell lymphomas constitute a heterogeneous and rare group of diseases with regional particularities in Latin America. OBJECTIVE: To determine the clinicopathological features, relative frequency and survival among patients from a Peruvian institution. METHODS: Primary cutaneous T-cell lymphomas were defined based on the absence of extracutaneous disease at diagnosis. Classification was performed following the 2008 World Health Organization Classification of Neoplasms of the Hematopoietic and Lymphoid tissues...
September 2017: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/29166332/testicular-estrogen-secreting-leydig-cell-tumor-in-18f-fdg-pet-ct-an-incidental-detection-in-a-patient-treated-by-chemotherapy-for-hodgkin-lymphoma
#12
Axel Van Der Gucht, Zaher Maged, Rodolfo Burruni, Jean-Luc Barras, Niklaus Schaefer
We present images of a 50-year-old man who referred for treatment of a classic Hodgkin lymphoma. While F-FDG PET/CT demonstrated a complete metabolic remission after chemotherapy, an increased F-FDG uptake of a right testicular lesion in F-FDG PET/CT and an unexplained bilateral gynecomastia were observed. A benign Leydig cell tumor was histopathologically proved after a right radical orchiectomy. The serum estradiol level was abnormally elevated reflecting the estrogen-secreting profile. This report highlights that a focal F-FDG uptake in the testicular region with unexplained gynecomastia should suggest the diagnosis of an estrogen-secreting Leydig cell tumor on F-FDG PET/CT...
November 22, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/29166329/pseudolesions-impersonating-osseous-tumor-involvement-on-both-contrast-enhanced-ct-and-fdg-pet-ct
#13
Jessica K Peterson, Rustain L Morgan, Joseph S Donald, Mark A Perry
A 27-year-old man with stage IV-B Hodgkin's lymphoma status post autologous peripheral stem cell transplant in 2015 with complete response, presented in 2017 with increasing back pain. Restaging contrast enhanced CT demonstrated left brachiocephalic vein occlusion with peripheral nodular high density areas within C7-T2 vertebral bodies with corresponding radiotracer uptake on same day PET/CT. No matching lesion was seen on noncontrast CT. Findings were consistent with pooling of contrast and radiotracer within vertebral venous plexus collaterals at the cervicothoracic junction secondary to brachiocephalic vein occlusion...
November 22, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/29166240/more-on-anti-cd19-car-t-cells-in-cns-diffuse-large-b-cell-lymphoma
#14
(no author information available yet)
New England Journal of Medicine, Volume 377, Issue 21, Page 2101-2102, November 2017.
November 23, 2017: New England Journal of Medicine
https://www.readbyqxmd.com/read/29165710/risk-of-soft-tissue-sarcoma-among-69-460-five-year-survivors-of-childhood-cancer-in-europe
#15
Chloe J Bright, Mike M Hawkins, David L Winter, Daniela Alessi, Rodrigue S Allodji, Francesca Bagnasco, Edit Bárdi, Andrea Bautz, Julianne Byrne, Elizabeth A M Feijen, Miranda M Fidler, Stanislaw Garwicz, Desiree Grabow, Thorgerdur Gudmundsdottir, Joyeeta Guha, Nadia Haddy, Momcilo Jankovic, Peter Kaatsch, Melanie Kaiser, Claudia E Kuehni, Helena Linge, Hilde Øfstaas, Cecile M Ronckers, Roderick Skinner, Jop C Teepen, Monica Terenziani, Giao Vu-Bezin, Finn Wesenberg, Thomas Wiebe, Carlotta Sacerdote, Zsuzsanna Jakab, Riccardo Haupt, Päivi Lähteenmäki, Lorna Zadravec Zaletel, Rahel Kuonen, Jeanette F Winther, Florent de Vathaire, Leontien C Kremer, Lars Hjorth, Raoul C Reulen
Background: Childhood cancer survivors are at risk of subsequent primary soft-tissue sarcomas (STS), but the risks of specific STS histological subtypes are unknown. We quantified the risk of STS histological subtypes after specific types of childhood cancer. Methods: We pooled data from 13 European cohorts, yielding a cohort of 69 460 five-year survivors of childhood cancer. Standardized incidence ratios (SIRs) and absolute excess risks (AERs) were calculated. Results: Overall, 301 STS developed compared with 19 expected (SIR = 15...
November 20, 2017: Journal of the National Cancer Institute
https://www.readbyqxmd.com/read/29165612/long-term-outcomes-of-107-cases-of-primary-thyroid-malt-lymphoma-at-a-single-medical-institution-in-japan
#16
Natsuko Watanabe, Hiroto Narimatsu, Jaeduk Yoshimura Noh, Kenji Iwaku, Yo Kunii, Nami Suzuki, Hidemi Ohye, Miho Suzuki, Masako Matsumoto, Ai Yoshihara, Kaori Kameyama, Kazuhiko Kobayashi, Masahiro Kami, Kiminori Sugino, Koichi Ito
Context: Thyroid mucosa-associated lymphoid tissue (MALT) lymphoma is a type of extranodal lymphoma with a favorable prognosis. Objective: To provide information on long-term outcomes that would facilitate establishment of the optimal management strategy for thyroid lymphoma. Design, Setting, and Participants: Medical records of 107 patients (median age 67 years, 20 males, 87 females) who were diagnosed with localized thyroid MALT lymphoma stage IE or IIE at Ito Hospital were retrospectively reviewed...
November 20, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29165611/a-case-of-hodgkin-lymphoma-mimicking-lymphomatoid-granulomatosis-diagnosed-at-autopsy
#17
Sujal Shah, Megan Smith, Randall Butler
Hodgkin lymphoma and lymphomatoid granulomatosis (LYG) are entities that contain a small number of large, variably Epstein-Barr virus (EBV)-positive neoplastic cells scattered within background non-neoplastic mixed inflammatory infiltrate. The 2 entities can typically be distinguished histologically by the angiocentric and angiodestructive pattern of lymphomatoid granulomatosis (LYG); also, they differ in overall prognosis. Herein, we report a case of Hodgkin lymphoma in a 64-year-old Caucasian woman, diagnosed at autopsy with unusual histologic features and aggressive clinical course that mimicked LYG...
November 20, 2017: Laboratory Medicine
https://www.readbyqxmd.com/read/29165368/human-protoparvoviruses
#18
REVIEW
Elina Väisänen, Yu Fu, Klaus Hedman, Maria Söderlund-Venermo
Next-generation sequencing and metagenomics have revolutionized the discovery of novel viruses. In recent years, three novel protoparvoviruses have been discovered in fecal samples of humans: bufavirus (BuV) in 2012, tusavirus (TuV) in 2014, and cutavirus (CuV) in 2016. BuV has since been studied the most, disclosing three genotypes that also represent serotypes. Besides one nasal sample, BuV DNA has been found exclusively in diarrheal feces, but not in non-diarrheal feces, suggesting a causal relationship...
November 22, 2017: Viruses
https://www.readbyqxmd.com/read/29165307/cutaneous-sarcoidosis-during-rituximab-treatment-for-microscopic-polyangiitis-an-uncommon-adverse-effect
#19
Leonardo Pescitelli, Giacomo Emmi, Lara Tripo, Linda Lazzeri, Maria Letizia Urban, Elena Silvesri, Margherita Vannucchi, Francesca Prignano
No abstract text is available yet for this article.
November 22, 2017: European Journal of Dermatology: EJD
https://www.readbyqxmd.com/read/29165301/early-and-sustained-remission-with-brentuximab-vedotin-in-a-case-of-disseminated-cutaneous-relapse-from-systemic-anaplastic-large-cell-lymphoma-refractory-to-chemotherapy
#20
David Aguiar-Bujanda, Arancha Dueñas-Comino, Camila Cabello, Jesus Bastida, José Carlos Rivero-Vera, Miguel Angel Limeres-González
No abstract text is available yet for this article.
November 22, 2017: European Journal of Dermatology: EJD
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