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Gangcheng Wu, Stuart K Johnson, Janet F Bornman, Sarita J Bennett, Michael W Clarke, Vijaya Singh, Zhongxiang Fang
Polyphenols in sorghum grains are a source of dietary antioxidants. Polyphenols in six diverse sorghum genotypes grown under two day/night temperature regimes of optimal temperature (OT, 32/21 °C and high temperature (HT, 38/21 °C) were investigated. A total of 23 phenolic compounds were positively or tentatively identified by HPLC-DAD-ESIMS. Compared with other pigmented types, the phenolic profile of white sorghum PI563516 was simpler, since fewer polyphenols were detected. Brown sorghum IS 8525 had the highest levels of caffeic and ferulic acid, but apigenin and luteolin were not detected...
February 24, 2016: Scientific Reports
Margherita Fabbri, Giorgio Leodori, Ricardo M Fernandes, Roongroj Bhidayasiri, Maria Jose Marti, Carlo Colosimo, Joaquim J Ferreira
The formation of neutralizing antibodies (NAbs) directed specifically against the active neurotoxin part of the botulinum neurotoxin (BoNT) complex is often cited as a major cause of secondary non-responsiveness (SnR) to treatment. This systematic and meta-analytic review evaluates the frequency of NAbs among patients treated with BoNT therapy for any clinical indication. A comprehensive database search strategy was designed to retrieve relevant clinical data from the published literature up to April 2013. All English-language publications that analyzed NAbs prevalence in more than ten patients were included, regardless of BoNT formulation, assay method, and study design...
January 2016: Neurotoxicity Research
Becky Mars, Jon Heron, Lucy Biddle, Jenny L Donovan, Rachel Holley, Martyn Piper, John Potokar, Clare Wyllie, David Gunnell
BACKGROUND: There is concern over the potential impact of the Internet on self-harm and suicidal behaviour, particularly in young people. However, little is known about the prevalence and patterns of suicide/self-harm related Internet use in the general population. METHODS: Cross sectional study of 3946 of the 8525 participants in the Avon Longitudinal Study of Parents and Children (ALSPAC) who were sent a self-report questionnaire including questions on suicide/self-harm related Internet use and self-harm history at age 21 years...
October 1, 2015: Journal of Affective Disorders
M E Garcés, C Sequeiros, N L Olivera
Vibrio alginolyticus is an opportunistic pathogen which may affect different aquatic organisms. The aim of this study was to assess the probiotic properties and the protective mode of action of Lactobacillus pentosus H16 against V. alginolyticus 03/8525, through in vitro and in vivo studies using Artemia franciscana (hereafter Artemia). This strain showed antimicrobial activity against V. alginolyticus 03/8525 and Aeromonas salmonicida subsp. salmonicida ATCC33658 possibly related to lactobacilli organic acid production...
February 10, 2015: Diseases of Aquatic Organisms
Jiří Smíd, Jiří Moravec, Petr Kodym, Lukáš Kratochvíl, Seyyed Saeed Hosseinian Yousefkhani, Daniel Frynta
We present a comprehensive summary of the distribution of the lizards of Iran accompanied by an annotated checklist. The updated maps of distribution of all 146 species of 41 genera of 11 families are based on all available bibliographic records, catalogues of museum collections and our own field observations. The final dataset used for the distribution maps contains 8525 georeferenced records and cover 41% of the country when plotted on a grid of 0.25° × 0.25° resolution. The dataset is publicly accessible through GBIF portal (http://www...
2014: Zootaxa
Yong-Taek Jung, Sooyeon Park, Jung-Sook Lee, Jung-Hoon Yoon
A Gram-negative, coccoid or oval-shaped and gliding bacterial strain, designated HDM-25(T), belonging to the Alphaproteobacteria, was isolated from a tidal flat sediment of the Yellow Sea, Korea, and was subjected to a polyphasic taxonomic study. Strain HDM-25(T) grew optimally at pH 7.0-8.0, at 30 °C and in the presence of 2-3% (w/v) NaCl. Neighbour-joining, maximum-likelihood and maximum-parsimony phylogenetic trees based on 16S rRNA gene sequences showed that strain HDM-25(T) fell within the clade comprising the species of the genus Paracoccus, clustering with the type strain of Paracoccus aminophilus, with which it exhibited the highest 16S rRNA gene sequence similarity (97...
August 2014: International Journal of Systematic and Evolutionary Microbiology
Nadia Balucani, Dimitrios Skouteris, Francesca Leonori, Raffaele Petrucci, Mathias Hamberg, Wolf D Geppert, Piergiorgio Casavecchia, Marzio Rosi
The dynamics of the H displacement channels in the reaction N((2)D) + C(2)H(4) have been investigated by the crossed molecular beam technique with mass spectrometric detection and time-of-flight analysis at two different collision energies (17.2 and 28.2 kJ/mol). The interpretation of the scattering results is assisted by new electronic structure calculations of stationary points and product energetics for the C(2)H(4)N ground state doublet potential energy surface. RRKM statistical calculations have been performed to derive the product branching ratio under the conditions of the present experiments and of the atmosphere of Titan...
November 1, 2012: Journal of Physical Chemistry. A
Alpesh Amin, Steven Deitelzweig, Rudell Christian, Keith Friend, Jay Lin, Kathy Belk, Dorothy Baumer, Timothy J Lowe
BACKGROUND: Hyponatremia is a prevalent electrolyte disorder in hospitalized patients indicative of greater morbidity and mortality. A large-scale retrospective analysis was conducted to evaluate the incremental burden of hospitalized hyponatremic (HN) versus non-HN patients in terms of hospital resource utilization, costs, and hospital readmissions in the real-world setting. METHODS: HN patients (≥18 years) were selected from the Premier Hospital Database between January 1, 2007 and March 31, 2010 and matched to a non-HN control cohort using propensity score matching...
October 2012: Journal of Hospital Medicine: An Official Publication of the Society of Hospital Medicine
Laura Sauerbeck, Richard Hornung, Daniel Woo, Charles J Moomaw, Craig Anderson, E Sander Connolly, Guy A Rouleau, Robert D Brown, Joseph P Broderick
BACKGROUND: Higher mortality for patients with aneurysmal subarachnoid haemorrhage has been reported. AIMS: In families with intracranial aneurysms, we sought to determine whether mortality among subjects with intracranial aneurysm (affected) was higher and related to rupture, compared with unaffected family members. METHODS: Subjects enrolled in the Familial Intracranial Aneurysm protocol were contacted yearly and their status was obtained...
December 2013: International Journal of Stroke: Official Journal of the International Stroke Society
Ying Lu, Qiong Wang, Qi-tian Mu, Zhi-mei Chen, Ji-yu Lou, Wan-mao Ni, Jie Jin
OBJECTIVE: To explore the expression and clinical significance of ID1 gene in acute myeloid leukemia (AML) patients. METHOD: Real-time quantitative PCR (RQ-PCR) was used to test the expression level of ID1 gene in 114 de novo adult AML patients, and the clinical features of these patients were analyzed. RESULTS: ID1 gene transcript levels were detectable in BM mononuclear cells from 114 patients with AML, the median expression level of all samples was 8525 (range: 57 - 11 233 238)...
April 2012: Zhonghua Xue Ye Xue za Zhi, Zhonghua Xueyexue Zazhi
Hyun-Woo Cho, Chung-Sik Yoon
In a previous study, we concluded that respirator testing with a sodium chloride aerosol gave a conservative estimate of filter penetration for welding fume aerosols. A rapid increase in the pressure drop (PD) of some respirators was observed as fumes accumulated on the filters. The present study evaluated particulate respirator PD based on workplace field tests. A field PD tester was designed and validated using the TSI 8130 Automatic Filter Tester, designed in compliance with National Institute for Occupational and Safety and Health regulation 42 CFR part 84...
October 2012: Annals of Occupational Hygiene
Irina Nikolova, Stijn Janssen, Peter Vos, Karl Vrancken, Vinit Mishra, Patrick Berghmans
The aim of this study is to investigate the dispersion of ultrafine particles and its spatial distribution in a street canyon and its neighbourhood with the 3D CFD model ENVI-met®. The performance of the model at street scale is evaluated and the importance of the boundary conditions like wind field and traffic emissions on the UFP concentration is demonstrated. To support and validate the modelled results, a short-term measurement campaign was conducted in a street canyon in Antwerp, Belgium. The UFP concentration was measured simultaneously with P-TRACK (TSI Model 8525) at four different locations in the canyon...
December 15, 2011: Science of the Total Environment
Yuxi Tian, Rafael Camacho, Daniel Thomsson, Michael Reus, Alfred R Holzwarth, Ivan G Scheblykin
Chlorosomes are the largest and most efficient natural light-harvesting systems and contain supramolecular assemblies of bacteriochlorophylls that are organized without proteins. Despite a recent structure determination for chlorosomes from Chlorobaculum tepidum (Ganapathy Proc. Natl. Acad. Sci. U.S.A. 2009, 106, 8525), the issue of a possible large structural disorder is still discussed controversially. We have studied individual chlorosomes prepared under very carefully controlled growth condition by a novel 2-dimensional polarization single molecule imaging technique giving polarization information for both fluorescence excitation and emission simultaneously...
November 2, 2011: Journal of the American Chemical Society
Lawrence W Potts, Peter W Carr
In this letter, we examine an equation that had been published in Analytical Chemistry in a paper entitled "Comprehensive Study on the Optimization of Online Two-Dimensional Liquid Chromatographic Systems Considering Losses in Theoretical Peak Capacity in First- and Second-Dimensions: A Pareto-Optimality Approach" by Vivo-Truyols, G.; van der Wal, Sj.; Schoenmakers, P. J. Anal. Chem. 2010, 82, 8525-8536. In that paper, the authors considered, among many issues, the effects of extra-column and column broadening on isocratic peak capacity...
October 15, 2011: Analytical Chemistry
Anne-Marie Leroi, Xavier Lenne, Benoît Dervaux, Emmanuel Chartier-Kastler, Brigitte Mauroy, Loïc Le Normand, Philippe Grise, Jean-Luc Faucheron, Yann Parc, Paul-Antoine Lehur, François Mion, Henri Damon, Xavier Barth, Albert Leriche, Christian Saussine, Laurent Guy, François Haab, Laurent Bresler, Jean-Pierre Sarramon, Henri Bensadoun, Eric Rullier, Karem Slim, Igor Sielezneff, Eric Mourey, Philippe Ballanger, Francis Michot
BACKGROUND: Sacral nerve modulation (SNM) is an established treatment for urinary and fecal incontinence in patients for whom conservative management has failed. OBJECTIVE: This study assessed the outcome and cost analysis of SNM compared to alternative medical and surgical treatments. METHODS: Clinical outcome and cost-effectiveness analyses were performed in parallel with a prospective, multicenter cohort study that included 369 consecutive patients with urge urinary and/or fecal incontinence...
April 2011: Annals of Surgery
A Tursi, W Elisei, G M Giorgetti, F Aiello, G Brandimarte
BACKGROUND: Ulcerative colitis with diverticulosis (UCD), segmental colitis associated with diverticulosis (SCAD) and acute uncomplicated diverticulitis (AUD) may affect the same colonic regions, but the real incidence of these entities in clinical practice is unknown. AIM: To assess the incidence and the endoscopic findings of UCD, SCAD and AUD. METHODS: From January 2004 to June 2009, 8525 consecutive colonoscopies were performed. Diagnosis of the diseases was based on specific endoscopic and histological (UCD and SCAD), and on endoscopic and radiological (AUD) patterns...
February 2011: Alimentary Pharmacology & Therapeutics
Lance A Wallace, Amanda J Wheeler, Jill Kearney, Keith Van Ryswyk, Hongyu You, Ryan H Kulka, Pat E Rasmussen, Jeff R Brook, Xiaohong Xu
Continuous monitors can be used to supplement traditional filter-based methods of determining personal exposure to air pollutants. They have the advantages of being able to identify nearby sources and detect temporal changes on a time scale of a few minutes. The Windsor Ontario Exposure Assessment Study (WOEAS) adopted an approach of using multiple continuous monitors to measure indoor, outdoor (near-residential) and personal exposures to PM₂.₅, ultrafine particles and black carbon. About 48 adults and households were sampled for five consecutive 24-h periods in summer and winter 2005, and another 48 asthmatic children for five consecutive 24-h periods in summer and winter 2006...
January 2011: Journal of Exposure Science & Environmental Epidemiology
Jeffrey Fernandez, Jamese J Hilliard, Darren Abbanat, Wenyan Zhang, John L Melton, Colleen M Santoro, Robert K Flamm, Karen Bush
Ceftobiprole, a broad-spectrum cephalosporin with activity against methicillin-resistant Staphylococcus aureus (MRSA) (P. Hebeisen et al., Antimicrob. Agents Chemother. 45:825-836, 2001), was evaluated in a subcutaneous skin infection model with Staphylococcus aureus Smith OC 4172 (methicillin-susceptible S. aureus [MSSA]), S. aureus OC 8525 (MRSA), Pseudomonas aeruginosa OC 4351 (having an inducible AmpC beta-lactamase), and P. aeruginosa OC 4354 (overproducing AmpC beta-lactamase). In the MSSA and MRSA infection models, ceftobiprole, administered as the prodrug ceftobiprole medocaril, was more effective in reducing CFU/g skin (P < 0...
January 2010: Antimicrobial Agents and Chemotherapy
H Geha, A François, Fx Boland, S Drikes, Jm Peron
The World Health Organisation (WHO) classified polymorphous low-grade adenocarcinoma (PLGA) in 1990 as a low-grade malignancy; ICD-O 8525/3 being the assigned international code. It has been frequently described as occurring in hard- or soft-palate accessory salivary glands: some cases being described in the tongue and in major salivary glands. We present an extensive literature review about PLGA and the most common diagnostic pitfalls. We also report the first case where it was seen surrounding an impacted maxillary tooth and discuss it in regard to our review...
June 2009: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
Virginia A Triant, Todd T Brown, Hang Lee, Steven K Grinspoon
CONTEXT: Reduced bone mineral density has been demonstrated among HIV-infected patients, but fracture prevalence is unknown. OBJECTIVE: The objective of the study was to compare fracture prevalence in HIV-infected and non-HIV-infected patients. DESIGN: This was a population-based study. SETTING: The study was conducted at a large U.S. health care system. PATIENTS: A total of 8525 HIV-infected and 2,208,792 non-HIV-infected patients with at least one inpatient or outpatient encounter between October 1, 1996, and March 21, 2008, was compared...
September 2008: Journal of Clinical Endocrinology and Metabolism
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