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https://www.readbyqxmd.com/read/28323604/why-it-s-unjust-to-expect-location-specific-language-specific-or-population-specific-service-from-students-with-underrepresented-minority-or-low-income-backgrounds
#1
Barret Michalec, Maria Athina Tina Martimianakis, Jon C Tilburt, Frederic W Hafferty
In this case we meet Amanda, a medical student of Native and Latin American ethnicity who receives financial aid. Her friends are surprised by her interest in an elite residency program. They suggest, rather, that with her language skills, ethnic background, and interest in social justice, she has a responsibility to work with underserved patient populations. In our commentary, we consider issues raised by the case and explore Amanda's friends' underlying expectations and assumptions that perpetuate the very inequities that the resolution of the case purports to address...
March 1, 2017: AMA Journal of Ethics
https://www.readbyqxmd.com/read/28255592/health-professions-students-perceptions-of-their-ipe-program-potential-barriers-to-student-engagement-with-ipe-goals
#2
Barret Michalec, Carolyn Giordano, Brandie Pugh, Christine Arenson, Elizabeth Speakman
BACKGROUND: Extensive evaluative efforts are underway to explore nuances of interprofessional education (IPE). Few studies, however, have utilized methodology that includes multiple interviews with students of various health disciplines, thereby potentially concealing factors that may be impacting students' attitudes and perceptions of IPE. By focusing on the students' perspectives, this case study explores potential barriers and facilitators to students' engagement with their IPE program...
2017: Journal of Allied Health
https://www.readbyqxmd.com/read/28243789/surgical-method-influences-specimen-margins-and-biochemical-recurrence-during-radical-prostatectomy-for-high-risk-prostate-cancer-a-systematic-review-and-meta-analysis
#3
REVIEW
Victor Srougi, Jose Bessa, Mohammed Baghdadi, Igor Nunes-Silva, Jose Batista da Costa, Silvia Garcia-Barreras, Eric Barret, Francois Rozet, Marc Galiano, Rafael Sanchez-Salas, Xavier Cathelineau
PURPOSE: To perform a meta-analysis comparing the rates of positive surgical margins (PSM) and biochemical recurrence (BCR) between open radical prostatectomy (ORP) and robot-assisted radical prostatectomy (RARP) in patients with high-risk prostate cancer. METHODS: A systematic review was performed on Pubmed, Embase and Scopus databases in August 2016, according to the Preferred Reporting Items for Systematic Review and Meta-analysis (PRISMA) statement. References retrieved were evaluated using the Newcastle-Ottawa scale and the Black and Down's tool for quality assessment...
February 27, 2017: World Journal of Urology
https://www.readbyqxmd.com/read/28243615/dataset-on-absorption-spectra-and-bulb-concentration-of-phenolic-compounds-that-may-interfere-with-onion-pyruvate-determinations
#4
Vanesa H Beretta, Florencia Bannoud, Marina Insani, Claudio R Galmarini, Pablo F Cavagnaro
We present data on absorption spectra (400-540 nm) and concentration of phenolic compounds quercetin, myricetin, kaempferol, rutin, catechin, epicatechin gallate (ECG) and epigallocatechin gallate (EGCG), in yellow, red and white onions. These data are related to the article entitled "Variability in spectrophotometric pyruvate analyses for predicting onion pungency and nutraceutical value" (Beretta et al., 2017) [1]. Given the relevance of pyruvate determinations for estimating onion pungency and functional value, it is important to identify compounds that can interfere with pyruvate determinations when using two previously published analytical procedures, namely Schwimmer and Weston (1961) (SW) [2] and Anthon and Barret (2002) (AB) [3], which are based on spectrophotometry and light-absorbance at 420 nm and 515 nm, respectively...
April 2017: Data in Brief
https://www.readbyqxmd.com/read/28228439/loss-of-pollen-specific-phospholipase-not-like-dad-triggers-gynogenesis-in-maize
#5
Laurine M Gilles, Abdelsabour Khaled, Jean-Baptiste Laffaire, Sandrine Chaignon, Ghislaine Gendrot, Jérôme Laplaige, Hélène Bergès, Genséric Beydon, Vincent Bayle, Pierre Barret, Jordi Comadran, Jean-Pierre Martinant, Peter M Rogowsky, Thomas Widiez
Gynogenesis is an asexual mode of reproduction common to animals and plants, in which stimuli from the sperm cell trigger the development of the unfertilized egg cell into a haploid embryo. Fine mapping restricted a major maize QTL (quantitative trait locus) responsible for the aptitude of inducer lines to trigger gynogenesis to a zone containing a single gene NOT LIKE DAD (NLD) coding for a patatin-like phospholipase A. In all surveyed inducer lines, NLD carries a 4-bp insertion leading to a predicted truncated protein...
March 15, 2017: EMBO Journal
https://www.readbyqxmd.com/read/28214412/histiocytoses-emerging-neoplasia-behind-inflammation
#6
REVIEW
Julien Haroche, Fleur Cohen-Aubart, Barret J Rollins, Jean Donadieu, Frédéric Charlotte, Ahmed Idbaih, Augusto Vaglio, Omar Abdel-Wahab, Jean-François Emile, Zahir Amoura
Histiocytoses are disorders characterised by inflammation and the accumulation of cells derived from the monocyte and macrophage lineages, which results in tissue damage. Although they are often considered rare disorders with protean clinical manifestations, considerable advances in the understanding of their genetics have led to increased clinical recognition of these conditions, and fuelled further insights into their pathogenesis. In this Review, we describe insights into the cells of origin, molecular pathology, clinical features, and treatment strategies for some of the most common histiocytic disorders, including Langerhans cell histiocytosis, Erdheim-Chester disease, and Rosai-Dorfman disease...
February 2017: Lancet Oncology
https://www.readbyqxmd.com/read/28202265/association-between-chronic-exposure-to-air-pollution-and-mortality-in-the-acute-respiratory-distress-syndrome
#7
Barret Rush, Robert C McDermid, Leo Anthony Celi, Keith R Walley, James A Russell, John H Boyd
The impact of chronic exposure to air pollution and outcomes in the acute respiratory distress syndrome (ARDS) is unknown. The Nationwide Inpatient Sample (NIS) from 2011 was utilized for this analysis. The NIS is a national database that captures 20% of all US in-patient hospitalizations from 47 states. Patients with ARDS who underwent mechanical ventilation from the highest 15 ozone pollution cities were compared with the rest of the country. Secondary analyses assessed outcomes of ARDS patients for ozone pollution and particulate matter pollution on a continuous scale by county of residence...
February 12, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28178046/acute-respiratory-distress-syndrome-in-pregnant-women
#8
Barret Rush, Pawel Martinka, Brett Kilb, Robert C McDermid, John H Boyd, Leo Anthony Celi
OBJECTIVE: To estimate the rate of acute respiratory distress syndrome (ARDS) in pregnant patients as well as to investigate clinical conditions associated with mortality. METHODS: We used the Nationwide Inpatient Sample from 2006 to 2012 to identify a cohort of pregnant patients who underwent mechanical ventilation for ARDS. A multivariate model predicting in-hospital mortality was created. RESULTS: A total of 55,208,382 hospitalizations from the 2006-2012 Nationwide Inpatient Samples were analyzed...
March 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28172843/p471-efficacy-and-safety-of-switching-from-reference-infliximab-to-biosimilar-infliximab-in-patients-with-inflammatory-bowel-disease-first-french-experience
#9
P-A Soret, C Prieux-Klotz, J Avouac, A Molto, M Dior, B Brieau, J Dreanic, M Camus, M Barret, R Coriat, O Conort, F Chast, C Goulvestre, C Le Jeunne, M Dougados, S Nahon, S Chaussade, V Abitbol
No abstract text is available yet for this article.
February 1, 2017: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/28159256/variability-in-spectrophotometric-pyruvate-analyses-for-predicting-onion-pungency-and-nutraceutical-value
#10
Vanesa H Beretta, Florencia Bannoud, Marina Insani, Claudio R Galmarini, Pablo F Cavagnaro
Onion pyruvate concentration is used as a predictor of flavor intensity and nutraceutical value. The protocol of Schwimmer and Weston (SW) (1961) is the most widespread methodology for estimating onion pyruvate. Anthon and Barret (AB) (2003) proposed modifications to this procedure. Here, we compared these spectrophotometry-based procedures for pyruvate analysis using a diverse collection of onion cultivars. The SW method always led to over-estimation of pyruvate levels in colored, but not in white onions, by up to 65%...
June 1, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28144947/comparative-primate-obstetrics-observations-of-15-diurnal-births-in-wild-gelada-monkeys-theropithecus-gelada-and-their-implications-for-understanding-human-and-nonhuman-primate-birth-evolution
#11
Nga Nguyen, Laura M Lee, Peter J Fashing, Niina O Nurmi, Kathrine M Stewart, Taylor J Turner, Tyler S Barry, Kadie R Callingham, C Barret Goodale, Bryce S Kellogg, Ryan J Burke, Emily K Bechtold, Megan J Claase, G Anita Eriksen, Sorrel C Z Jones, Jeffrey T Kerby, Jacob B Kraus, Carrie M Miller, Thomas H Trew, Yi Zhao, Evan C Beierschmitt, Malcolm S Ramsay, Jason D Reynolds, Vivek V Venkataraman
OBJECTIVES: The birth process has been studied extensively in many human societies, yet little is known about this essential life history event in other primates. Here, we provide the most detailed account of behaviors surrounding birth for any wild nonhuman primate to date. MATERIALS AND METHODS: Over a recent ∼10-year period, we directly observed 15 diurnal births (13 live births and 2 stillbirths) among geladas (Theropithecus gelada) at Guassa, Ethiopia. During each birth, we recorded the occurrence (or absence) of 16 periparturitional events, chosen for their potential to provide comparative evolutionary insights into the factors that shaped birth behaviors in humans and other primates...
February 1, 2017: American Journal of Physical Anthropology
https://www.readbyqxmd.com/read/28130190/the-immunologic-considerations-in-human-head-transplantation
#12
REVIEW
Mark A Hardy, Allen Furr, Juan P Barret, John H Barker
The idea of head transplantation appears at first as unrealistic, unethical, and futile. Here we discuss immunological considerations in human head transplantation. In a separate accompanying article we discuss surgical, ethical, and psychosocial issues concerned in body-to-head transplantation (BHT) [1]. The success of such an unusual allograft, where the donor and the recipient can reject each other, depends on prevention of complex immunologic reactions, especially rejection of the head by the body (graft-vs-host) or probably less likely, the possibility of the head rejecting the total body allograft (host-vs-graft)...
January 24, 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/28117215/learning-curve-of-minimally-invasive-radical-prostatectomy-comprehensive-evaluation-and-cumulative-summation-analysis-of-oncological-outcomes
#13
Arjun Sivaraman, Rafael Sanchez-Salas, Dominique Prapotnich, Kaixin Yu, Fabien Olivier, Fernando P Secin, Eric Barret, Marc Galiano, François Rozet, Xavier Cathelineau
BACKGROUND AND OBJECTIVE: The primary objective was to evaluate the learning curve of minimally invasive radical prostatectomy (MIRP) in our institution and analyze the salient learning curve transition points regarding oncological outcomes. METHODS: Clinical, pathologic, and oncological outcome data were collected from our prospectively collected MIRP database to estimate positive surgical margin (PSM) and biochemical recurrence (BCR) trends during a 15-year period from 1998 to 2013...
January 20, 2017: Urologic Oncology
https://www.readbyqxmd.com/read/28117128/how-consumers-of-plastic-water-bottles-are-responding-to-environmental-policies
#14
Caroline Orset, Nicolas Barret, Aurélien Lemaire
Although plastic induces environmental damages, almost all water bottles are made from plastic and the consumption never stops increasing. This study evaluates the consumers' willingness to pay (WTP) for different plastics used for water packaging. Successive messages emphasizing the characteristics of plastic are delivered to consumers allowing explaining the influence of information on the consumers' WTP. We find that information has a manifest effect on the WTP. We show there is a significant premium associated with recycled plastic packaging and biodegradable bioplastic packaging...
January 20, 2017: Waste Management
https://www.readbyqxmd.com/read/28110028/surgical-ethical-and-psychosocial-considerations-in-human-head-transplantation
#15
REVIEW
Allen Furr, Mark A Hardy, Juan P Barret, John H Barker
Transplanting a head and brain is perhaps the final frontier of organ transplantation. The goal of body-to-head transplantation (BHT) is to sustain the life of individuals who suffer from terminal disease, but whose head and brain are healthy. Ideally BHT could provide a lifesaving treatment for several conditions where none currently exists. BHT is no ordinary experiment, to transfer a head to another body involves extraordinarily complex medical challenges as well as ethical and existential dilemmas that were previously confined to the imagination of writers of fiction...
January 19, 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/28063585/extraneous-fibre-traces-brought-by-river-water-a-case-study
#16
L Lepot, T Vanden Driessche, K Lunstroot, A Barret, F Gason, K De Wael
The fibre traces on a young victim found underwater were mostly single fibre traces besides small amounts of fibre collectives indistinguishable from his parents clothes (mainly wool). Most of those single fibre traces were blue-grey polyester fibres showing tiny differences among each other. They were unexpected according to known population fibre studies. One year after the victim's discovery experiments were conducted to evaluate the possible contamination with fibres from river water. A small amount of extraneous fibres were collected among which blue and grey-black cotton and man-made (mainly polyester) fibres...
January 2017: Science & Justice: Journal of the Forensic Science Society
https://www.readbyqxmd.com/read/28007641/the-association-between-anemia-and-neurological-outcome-in-hypoxic-ischemic-brain-injury-after-cardiac-arrest
#17
Andrew Wormsbecker, Mypinder S Sekhon, Donald E Griesdale, Katie Wiskar, Barret Rush
AIM: To examine the relationship between daily mean hemoglobin concentration and neurological outcome in hypoxic ischemic brain injury (HIBI) following cardiac arrest. METHODS: We conducted a single center retrospective observational study using a database of HIBI patients between March 2009 and December 2014. We included all adults admitted to the intensive care unit following an in-hospital or out-of-hospital cardiac arrest. The primary outcome was neurological outcome measured by the Cerebral Performance Category (CPC) at hospital discharge...
March 2017: Resuscitation
https://www.readbyqxmd.com/read/28007457/padeliporfin-vascular-targeted-photodynamic-therapy-versus-active-surveillance-in-men-with-low-risk-prostate-cancer-clin1001-pcm301-an-open-label-phase-3-randomised-controlled-trial
#18
Abdel-Rahmène Azzouzi, Sébastien Vincendeau, Eric Barret, Antony Cicco, François Kleinclauss, Henk G van der Poel, Christian G Stief, Jens Rassweiler, Georg Salomon, Eduardo Solsona, Antonio Alcaraz, Teuvo T Tammela, Derek J Rosario, Francisco Gomez-Veiga, Göran Ahlgren, Fawzi Benzaghou, Bertrand Gaillac, Billy Amzal, Frans M J Debruyne, Gaëlle Fromont, Christian Gratzke, Mark Emberton
BACKGROUND: Vascular-targeted photodynamic therapy, a novel tissue-preserving treatment for low-risk prostate cancer, has shown favourable safety and efficacy results in single-arm phase 1 and 2 studies. We compared this treatment with the standard of care, active surveillance, in men with low-risk prostate cancer in a phase 3 trial. METHODS: This randomised controlled trial was done in 47 European university centres and community hospitals. Men with low-risk, localised prostate cancer (Gleason pattern 3) who had received no previous treatment were randomly assigned (1:1) to vascular-targeted photodynamic therapy (4 mg/kg padeliporfin intravenously over 10 min and optical fibres inserted into the prostate to cover the desired treatment zone and subsequent activation by laser light 753 nm with a fixed power of 150 mW/cm for 22 min 15 s) or active surveillance...
February 2017: Lancet Oncology
https://www.readbyqxmd.com/read/28006957/the-role-of-robot-assisted-radical-prostatectomy-in-high-risk-prostate-cancer
#19
Victor Srougi, Rafael R Tourinho-Barbosa, Igor Nunes-Silva, Mohammed Baghdadi, Silvia Garcia-Barreras, Gregory Rembeyo, Sophie S Eiffel, Eric Barret, Francois Rozet, Marc Galiano, Rafael Sanchez-Salas, Xavier Cathelineau
Prostate cancer (PCa) is stratified into different risk categories based on the patient's prognosis. High-risk disease was formerly characterized by an increased risk of metastasis and lethality, requiring complex treatments. Surgery was recently highlighted to have a pivotal role for the treatment of such cases, even as monotherapy. In the past, open radical prostatectomy was performed for most patients with high-risk PCa; however, robot-assisted radical prostatectomy (RARP) emerged as a reasonable option because it provided optimal outcomes for low- and intermediate-risk PCa...
March 2017: Journal of Endourology
https://www.readbyqxmd.com/read/27984673/co-occurrence-of-histone-h3-k27m-and-braf-v600e-mutations-in-paediatric-midline-grade-i-ganglioglioma
#20
Mélanie Pagès, Kevin Beccaria, Nathalie Boddaert, Raphaël Saffroy, Aurore Besnard, David Castel, Frédéric Fina, Doriane Barets, Emilie Barret, Ludovic Lacroix, Franck Bielle, Felipe Andreiuolo, Arnault Tauziède-Espariat, Dominique Figarella-Branger, Stéphanie Puget, Jacques Grill, Fabrice Chrétien, Pascale Varlet
Ganglioglioma (GG) is a grade I tumor characterized by alterations in the MAPK pathway, including BRAF V600E mutation. Recently, diffuse midline glioma with an H3 K27M mutation was added to the WHO 2016 classification as a new grade IV entity. As co-occurrence of H3 K27M and BRAF V600E mutations has been reported in midline tumors and anaplastic GG, we searched for BRAF V600E and H3 K27M mutations in a series of 54 paediatric midline grade I GG (midline GG) to determine the frequency of double mutations and its relevance for prognosis...
December 16, 2016: Brain Pathology
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