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https://www.readbyqxmd.com/read/29041014/colon-inflammatory-fibroid-polyp-in-a-patient-with-von-recklinghausen-s-disease-endoscopic-aspect-with-narrow-band-imaging-and-magnification
#1
Julie Benard, Jérôme Rivory, Florian Rostain, Céline Montuclard, Valérie Hervieu, Thierry Ponchon, Mathieu Pioche
No abstract text is available yet for this article.
October 17, 2017: Endoscopy
https://www.readbyqxmd.com/read/29040053/periostin-as-a-biomarker-for-nasal-polyps-in-chronic-rhinosinusitis
#2
Alice Z Maxfield, Lukas D Landegger, Christopher D Brook, Ashton E Lehmann, Adam P Campbell, Regan W Bergmark, Konstantina M Stankovic, Ralph Metson
Objective Periostin is an extracellular matrix protein that is elevated in the sinonasal tissues of patients with chronic rhinosinusitis (CRS). The purpose of this study was to determine whether serum periostin could serve as a molecular biomarker of nasal polyp burden in sinonasal disease. Study Design Prospective cohort study. Setting Academic medical center. Subjects and Methods Serum periostin levels were measured by ELISA on blood samples collected from patients undergoing sinus surgery for CRS (n = 71), further stratified by phenotype as defined by nasal polyps and asthma...
October 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/29035351/rebalancing-%C3%AE-amyloid-induced-decrease-of-atp-level-by-amorphous-nano-micro-polyphosphate-suppression-of-the-neurotoxic-effect-of-amyloid-%C3%AE-protein-fragment-25-35
#3
Werner E G Müller, Shunfeng Wang, Maximilian Ackermann, Meik Neufurth, Renate Steffen, Egherta Mecja, Rafael Muñoz-Espí, Qingling Feng, Heinz C Schröder, Xiaohong Wang
Morbus Alzheimer neuropathology is characterized by an impaired energy homeostasis of brain tissue. We present an approach towards a potential therapy of Alzheimer disease based on the high-energy polymer inorganic polyphosphate (polyP), which physiologically occurs both in the extracellular and in the intracellular space. Rat pheochromocytoma (PC) 12 cells, as well as rat primary cortical neurons were exposed to the Alzheimer peptide Aβ25-35. They were incubated in vitro with polyphosphate (polyP); ortho-phosphate was used as a control...
October 16, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29034234/interleukin-13-in-asthma-and-other-eosinophilic-disorders
#4
Emma Doran, Fang Cai, Cécile T J Holweg, Kit Wong, Jochen Brumm, Joseph R Arron
Asthma is characterized by episodic, reversible airflow obstruction associated with variable levels of inflammation. Over the past several decades, there has been an increasing appreciation that the clinical presentation of asthma comprises a diverse set of underlying pathologies. Rather than being viewed as a single disease entity, asthma is now thought of as a clinical syndrome with the involvement of multiple pathological mechanisms. While it is appreciated that eosinophilia is present in only a subset of patients, it remains a key feature of asthma and other eosinophilic disorders such as atopic dermatitis, eosinophilic esophagitis, and chronic rhinosinusitis with nasal polyps...
2017: Frontiers in Medicine
https://www.readbyqxmd.com/read/29034092/choosing-the-uterine-preservation-surgery-for-placental-polyp-determined-by-blood-flow-evaluation-a-retrospective-cohort-study
#5
Sumire Sorano, Tatsuya Fukami, Maki Goto, Sakiko Imaoka, Miho Ando, Yoko To, Sumie Nakamura, Hiroko Yamamoto, Fuyuki Eguchi, Hiroshi Tsujioka
BACKGROUND: A placental polyp is an intrauterine polypoid mass or pedunculated mass occurring from residual trophoblastic tissue following abortion, cesarean section or vaginal delivery. Recently uterine preservation surgery represented by transcervical resection (TCR) has been performed for placental polyps. However TCR without intravascular intervention, including uterine artery embolization (UAE) may cause profound bleeding which necessitate emergency laparotomy. METHODS: Seventeen cases of placental polyp were retrospectively examined...
November 2017: Annals of Medicine and Surgery
https://www.readbyqxmd.com/read/29033778/a-case-of-basaloid-squamous-cell-carcinoma-of-polypoid-type-in-the-esophagus
#6
Ki Hun Lee, Sang Jin Lee, Hak Soo Kim, Sung Eun Kim, Soo Yong Choi, Hyun Ju Lee, Suk Hun Ha, Kwang Hoon Oh, Dae-Woon Eom
Basaloid squamous cell carcinoma of the esophagus is very rare. Further, polypoid type of esophageal cancer is also rare. We have recently treated a case of basaloid squamous cell carcinoma which presented as a 1.3-cm esophageal polyp. A 48-year-old woman was referred to our hospital because of a polypoid mass at 36 cm distance from the upper incisor on endoscopic examination, and the result of the biopsy was basaloid squamous cell carcinoma. The patient underwent Ivor Lewis operation with lymph node dissection...
September 2017: Case Reports in Gastroenterology
https://www.readbyqxmd.com/read/29033760/colonic-ganglioneuroma-a-rare-finding-during-colorectal-cancer-screening
#7
Emmanuel Ofori, Mel Ona, Daryl Ramai, Tiangui Huang, Philip Xiao, Madhavi Reddy
Ganglioneuromas are very rare clinical entities, and their occurrence in the large bowel lays further emphasis on their rarity. Ganglioneuromas are benign tumors of undifferentiated neural crest cells. Their clinical presentation is mostly asymptomatic, and if any symptoms are present at all, they are usually nonspecific, with excellent prognosis. We report an asymptomatic, 65-year-old male with a solitary ascending colonic polyp found on screening colonoscopy. Histology revealed benign polypoid spindle-cell proliferation as well as S100 reactivity, consistent with ganglioneuroma...
May 2017: Case Reports in Gastroenterology
https://www.readbyqxmd.com/read/29033329/nanoscale-visualization-of-biomineral-formation-in-coral-proto-polyps
#8
Tali Mass, Jeana L Drake, John M Heddleston, Paul G Falkowski
Calcium carbonate platforms produced by reef-building stony corals over geologic time are pervasive features around the world [1]; however, the mechanism by which these organisms produce the mineral is poorly understood (see review by [2]). It is generally assumed that stony corals precipitate calcium carbonate extracellularly as aragonite in a calcifying medium between the calicoblastic ectoderm and pre-existing skeleton, separated from the overlying seawater [2]. The calicoblastic ectoderm produces extracellular matrix (ECM) proteins, secreted to the calcifying medium [3-6], which appear to provide the nucleation, alteration, elongation, and inhibition mechanisms of the biomineral [7] and remain occluded and preserved in the skeleton [8-10]...
October 11, 2017: Current Biology: CB
https://www.readbyqxmd.com/read/29032231/schistosoma-japonicum-presenting-as-colon-polyps
#9
Amirali Kiyani, Anika Walia, Keng-Yu Chuang
No abstract text is available yet for this article.
October 12, 2017: American Journal of Medicine
https://www.readbyqxmd.com/read/29031394/the-role-of-cysteinyl-leukotrienes-and-their-receptors-in-refractory-nasal-polyps
#10
Jintao Du, Luo Ba, Jiao Zhou, Lingyu Yu, Ruowu Liu, Jie Zhang, Feng Liu, Junming Xian, Shixi Liu, Yafeng Liu
Leukotriene signaling is essential in many diseases, including asthma, allergic rhinitis, atherosclerosis and inflammatory bowel disease. Nevertheless, the expression of cysteinyl leukotrienes (CysLTs) and its receptors (CYSLTRs) in different types of nasal polyps (NPs), and the role of their antagonist in the treatment of refractory chronic rhinosinusitis with nasal polyps (CRSwNP) are not well understood. The following study investigates the expression of CysLTs and CYSLTRs in different types of NPs, as well as the role of leukotriene receptor antagonist (montelukast) in refractory NPs...
November 2017: Prostaglandins, Leukotrienes, and Essential Fatty Acids
https://www.readbyqxmd.com/read/29030500/prolapsed-antrochoanal-polyp-an-unusual-cause-of-acute-adult-respiratory-distress
#11
Thomas Terence Whittle, Stuart Benzie, Daniel Graham
Here we describe an adult male who presented with acute dyspnoea and airway occlusion. Nasoendoscopy revealed a large antrochoanal polyp extending from his maxillary sinus to the level of the epiglottis. The patient underwent a successful semi-emergency polypectomy following initial stabilisation with medication.
October 13, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/29030001/the-occurrence-and-characteristics-of-endoscopically-unexpected-malignant-degeneration-in-large-rectal-adenomas
#12
Maxime E S Bronzwaer, Gijsbert D Musters, Renée M Barendse, Lianne Koens, Eelco J R de Graaf, Pascal G Doornebosch, Mathijs P Schwartz, Esther C J Consten, Erik J Schoon, Ignace H J T de Hingh, Pieter J Tanis, Evelien Dekker, Paul Fockens
INTRODUCTION: Large non-pedunculated rectal polyps are most commonly resected by endoscopic mucosal resection (EMR) or transanal endoscopic microsurgery (TEM). Despite preprocedural diagnostics, unexpected rectal cancer is incidentally encountered within the resected specimen. This study aimed to compare the diagnostic assessment and procedural characteristics of lesions with and without unexpected submucosal invasion. METHODS: A post-hoc analysis of a multicenter randomized trial (TREND study) was performed, in which patients with a non-pedunculated rectal polyp of ≥3 cm without endoscopic suspicion of invasive growth were randomized between EMR and TEM...
October 10, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29029830/responsiveness-of-persian-version-of-consensus-auditory-perceptual-evaluation-of-voice-cape-v-persian-version-of-voice-handicap-index-vhi-and-praat-in-vocal-mass-lesions-with-muscle-tension-dysphonia
#13
Hassan Khoramshahi, Ahmad Reza Khatoonabadi, Seyyedeh Maryam Khoddami, Peyman Dabirmoghaddam, Noureddin Nakhostin Ansari
OBJECTIVES: This study was aimed at determining the internal and external responsiveness of the Persian version of the Consensus Auditory-Perceptual Evaluation of Voice (called ATSHA), Persian version of the Voice Handicap Index (VHI), and Praat scales among patients with vocal mass lesions and secondary muscle tension dysphonia. STUDY DESIGN: Prospective, within-participant repeated measures. METHOD: Thirty patients with vocal fold nodules, polyps, and cysts related to secondary muscle tension dysphonia participated in the study...
October 10, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/29027718/hypervascular-retained-product-of-conception-characteristic-magnetic-resonance-imaging-and-possible-relationship-to-placental-polyp-and-pseudoaneurysm
#14
Yuji Shiina, Takatomo Itagaki, Hiroya Ohtake
The cases of two patients who developed myometrial vascularization following dilatation and curettage are described. In case 1, pathological diagnosis was possible with the resected specimens. This patient had hypervascular retained products of conception (RPOC). In case 2, the natural course of this pathological condition was observed, confirming a process of regression during repeated withdrawal bleeding. The three principal magnetic resonance imaging (MRI) findings in these cases were: (i) presence of a remnant; (ii) breaking of the junctional zone in contact with the remnant; and (iii) vascularization/flow voids infiltrating into the myometrium from the broken junctional zone...
October 13, 2017: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/29026865/rare-gastric-cardia-polyp-causing-complete-esophageal-obstruction
#15
Kyley Leroy, Brian Moy, Houman Rezaizadeh
A 67-year-old man presented with food impaction and was found to have a gastric polyp obstructing the esophageal outlet. Due to the polyp's location and size, no immediate endoscopic intervention was performed, and the patient returned for intraoperative endoscopy and polypectomy. Cases of gastric polyps causing esophageal obstruction have not been identified in the literature. This case is unique for the location and size of the polyp, necessitating concomitant surgical management.
2017: ACG Case Reports Journal
https://www.readbyqxmd.com/read/29025731/macrophage-depletion-using-clodronate-liposomes-decreases-tumorigenesis-and-alters-gut-microbiota-in-the-aom-dss-mouse-model-of-colon-cancer
#16
Jackie E Bader, Reilly T Enos, Kandy T Velazquez, Meredith S Carson, Mitzi Nagarkatti, Prakash S Nagarkatti, Ioulia Chatzistamou, J Mark Davis, James A Carson, Cory Robinson, E Angela Murphy
We examined the role of macrophages in inflammation associated colorectal cancer (CRC). Given the emerging evidence on immune-microbiota interactions in CRC, we also sought to examine the interaction between macrophages and gut microbiota. To induce CRC, male C57BL/6 mice (n=32) received a single injection of azoxymethane (AOM) followed by three cycles of dextran sodium sulfate (DSS) supplemented water at weeks 1, 4, and 7, respectively. Prior to the final DSS cycle (week 7) and twice weekly until sacrifice, mice (n=16/group) received either 200μl i...
October 12, 2017: American Journal of Physiology. Gastrointestinal and Liver Physiology
https://www.readbyqxmd.com/read/29025352/risk-of-colorectal-polyps-and-of-malignancies-in-asymptomatic-carriers-of-mutations-in-the-main-dna-mismatch-repair-genes
#17
Maurizio Ponz de Leon, Monica Pedroni, Annalisa Pezzi, Blerta Sulce, Luca Roncucci, Federica Domati, Giuseppina Rossi, Luca Reggiani Bonetti
OBJECTIVE: Mutation carriers (Mut+) in DNA mismatch repair genes are predisposed to cancer of various organs and to adenomatous polyps; however, they may remain asymptomatic and cancer or polyp-free for several years. We purposed to analyse the clinical follow-up of individuals carrying constitutional mutations in the MLH1, MSH2 or MSH6 genes who were unaffected by benign polyps or malignant tumours at diagnosis. MATERIAL AND METHODS: Mut + subjects (n.81) were members of Lynch syndromes in whom mutations were detected between 1993 and 2015; all were asymptomatic at diagnosis...
October 12, 2017: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/29024705/management-of-a-circumferential-duodenal-polyp
#18
Andrew C Storm, Mark D Topazian
No abstract text is available yet for this article.
October 9, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29024448/isolated-sphenoid-sinus-opacifications-a-systematic-review-and-meta-analysis
#19
REVIEW
William J Moss, Andrey Finegersh, Aria Jafari, Bharat Panuganti, Charles S Coffey, Adam DeConde, Jacob Husseman
BACKGROUND: Isolated sphenoid sinus opacifications (ISSOs) represent a relatively uncommon disease with the potential for serious complications. To better understand this disease, we performed a systematic review to further characterize the underlying pathologies, associated symptoms, and treatment outcomes of patients with ISSOs. METHODS: A systematic review of ISSO case series was performed utilizing the Medline, Embase, Web of Science, and Cochrane databases in accordance with guidelines established by PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses)...
October 12, 2017: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/29024311/collagen-inducing-biologization-of-prosthetic-material-for-hernia-repair-polypropylene-meshes-coated-with-polyp-collagen
#20
Maximilian Ackermann, Xiaohong Wang, Shunfeng Wang, Meik Neufurth, Heinz C Schröder, Friedrich-Eckart Isemer, Werner E G Müller
Prostethic mesh material such as nonabsorbable polypropylene used in open and laparoscopic hernia repair are characterized by controllable mechanical properties but may elicit undesirable physiological reactions due to the nonphysiological inert polymer material. We succeeded in developing a biocompatible coating for these meshes, based on a physiological inorganic polymer, polyphosphate (polyP) that is morphogenetically active and used as a metabolic energy source, and a collagen matrix. The polyP/collagen hydrogel material was prepared by a freeze-extraction method, with amorphous Ca-polyP microparticles...
October 10, 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
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