keyword
MENU ▼
Read by QxMD icon Read
search

follicle ovary

keyword
https://www.readbyqxmd.com/read/28645781/immunomodulatory-mechanism-of-bushen-huoxue-recipe-alleviates-cyclophosphamide-induced-diminished-ovarian-reserve-in-mouse-model
#1
Cong Huang, Kunkun Song, Wenwen Ma, Jiahui Ding, Zhuo Chen, Mingmin Zhang
ETHNOPHARMACOLOGICAL RELEVANCE: Bushen Huoxue recipe (BHR) is a Chinese herbal prescription composed of ten herbs and it is widely used for the treatment of diminished ovarian reserve (DOR). This study investigates the potentially beneficial effects and underlying mechanism of BHR on a cyclophosphamide (CTX) induced model of DOR in mice. MATERIALS AND METHODS: Granules of BHR were first subjected to high performance liquid chromatography (HPLC) to determine the exact ingredients within the mixture...
June 20, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28641572/a-child-with-hypertension-and-ambiguous-genitalia-an-uncommon-variant-of-congenital-adrenal-hyperplasia-a-case-report
#2
Vivek Pant, Suman Baral, Bishal Shrestha, Arjun Tumbapo
BACKGROUND: Deficiency in 11β-hydroxylase as a cause of congenital adrenal hyperplasia is uncommon. It should be considered in the differential diagnosis of hypertension with virilization in any prepubescent child. CASE PRESENTATION: A 12-year-old Asian boy from eastern Nepal presented with pain in his abdomen and hypertension. He was raised as a male but had absent testicles since birth and had precocious puberty. Plasma testosterone, follicle-stimulating hormone, and luteinizing hormone were below baseline level...
June 23, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28639397/ovarian-polarity-and-cell-shape-determination-by-btk29a-in-drosophila
#3
Noriko Hamada-Kawaguchi, Daisuke Yamamoto
Drosophila Btk29A is a Tec family nonreceptor tyrosine kinase, the ortholog of which causes X-linked agammagluburinemia in humans when mutant. In Btk29A(ficP) mutant ovaries, multiple defects are observed: extra polar cells form ectopically; osk mRNA fails to accumulate posteriorly in mature oocytes; the shape and alignment of follicle cells are grossly distorted. All these phenotypes are rescued by selectively overexpressing the type 2 isoform of wild-type Btk29A in follicle cells. Expression of certain proteins enriched in adherens junctions is markedly affected in Btk29A(ficP) mutants; the anterior-posterior gradient normally observed in the expression of DE-Cadherin and Armadillo are lost and Canoe is sequestered from adherens junctions...
June 22, 2017: Genesis: the Journal of Genetics and Development
https://www.readbyqxmd.com/read/28630466/comparative-effectiveness-of-9-ovulation-induction-therapies-in-patients-with-clomiphene-citrate-resistant-polycystic-ovary-syndrome-a-network-meta-analysis
#4
Yiping Yu, Lanlan Fang, Ruizhe Zhang, Jingyan He, Yujing Xiong, Xiaoyi Guo, Qingyun Du, Yan Huang, Yingpu Sun
The comparative efficacies of ovulation-induction treatments in patients with clomiphene citrate-resistant (CCR) polycystic ovary syndrome (PCOS) are not well known. Therefore, we conducted a network meta-analysis to rank the reproductive efficacies of these treatments. We ultimately included 26 randomized clinical trials with 2722 participants and 9 types of therapies: clomiphene citrate (CC), metformin, letrozole, follicle stimulating hormone (FSH), human menopausal gonadotropin (hMG), unilateral laparoscopic ovarian drilling (ULOD), bilateral laparoscopic ovarian drilling (BLOD), the combination of metformin with letrozole (metformin+letrozole), and the combination of metformin with CC (metformin+CC)...
June 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28628258/tankyrase-inhibition-regulates-corpus-luteum-development-and-luteal-function-in-gonadotropin-treated-rats
#5
Accialini Paula, Irusta Griselda, Bechis Andres, Bas Diana, Parborell Fernanda, Abramovich Dalhia, Tesone Marta
Tankyrases are physiological regulators of Axin, a protein involved in several cellular processes, including Wnt signaling. Here, we investigated the effect of a specific Tankyrase inhibitor (XAV939) in follicular-luteal dynamics, and its possible relationship with ovarian vascular development. Studies were designed to analyze the effect of intrabursa administration of XAV939 in gonadotropin-treated prepubertal rats. In particular, we examined follicle and corpus luteum development, steroidogenesis, angiogenic markers, and apoptotic parameters...
June 19, 2017: Molecular Reproduction and Development
https://www.readbyqxmd.com/read/28626555/live-imaging-of-follicle-stimulating-hormone-receptors-in-gonads-and-bones-using-near-infrared-ii-fluorophore
#6
Yi Feng, Shoujun Zhu, Alexander L Antaris, Hao Chen, Yuling Xiao, Xiaowei Lu, Linlin Jiang, Shuo Diao, Kuai Yu, Yan Wang, Sonia Herraiz, Jingying Yue, Xuechuan Hong, Guosong Hong, Zhen Cheng, Hongjie Dai, Aaron J Hsueh
In vivo imaging of hormone receptors provides the opportunity to visualize target tissues under hormonal control in live animals. Detecting longer-wavelength photons in the second near-infrared window (NIR-II, 1000-1700 nm) region affords reduced photon scattering in tissues accompanied by lower autofluorescence, leading to higher spatial resolution at up to centimeter tissue penetration depths. Here, we report the conjugation of a small molecular NIR-II fluorophore CH1055 to a follicle stimulating hormone (FSH-CH) for imaging ovaries and testes in live mice...
May 1, 2017: Chemical Science
https://www.readbyqxmd.com/read/28624501/new-biomarkers-for-diagnosis-and-management-of-polycystic-ovary-syndrome
#7
REVIEW
Sidika E Karakas
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder affecting young women. Even though the definition of PCOS has changed over the years, all diagnostic criteria include two or more of the following: oligomenorrhea/oligoovulation/anovulation, androgen excess and polycystic ovaries (PCO). Traditional method of assessing the ovarian morphology has been transvaginal pelvic ultrasound. Recent studies support that serum anti-Mullerian hormone (AMH) levels correlate with the number of ovarian follicles and cysts...
June 15, 2017: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/28624344/effect-of-obesity-and-its-related-metabolic-factors-on-serum-anti-m%C3%A3-llerian-hormone-concentrations-in-women-with-and-without-polycystic-ovaries
#8
Tiphaine Lefebvre, Agathe Dumont, Pascal Pigny, Didier Dewailly
The relationship between serum anti-Müllerian hormone (AMH) levels, body mass index (BMI) and related metabolic factors were investigated in women with polycystic ovary syndrome (PCOS). A total of 691 women aged between 18 and 35 years, referred to the Department of Gynaecological Endocrinology at the University Hospital of Lille between 2009 and 2014 were included: 137 controls and 554 women with PCOS. Mean serum AMH levels were slightly but significantly lower in women with PCOS who were overweight or obese (BMI ≥25) compared with women of normal weight (BMI <25) (P < 0...
June 3, 2017: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/28620546/ovarian-morphology-is-associated-with-insulin-resistance-in-women-with-polycystic-ovary-syndrome-a-cross-sectional-study
#9
Sara Pittenger Reid, Chia-Ning Kao, Lauri Pasch, Kanade Shinkai, Marcelle I Cedars, Heather G Huddleston
BACKGROUND: Polycystic ovary syndrome (PCOS) is a very common disorder well known to be associated with insulin resistance and metabolic disease. Insulin resistance is likely involved in the promotion of the PCOS reproductive phenotype and may mediate some of the ovarian morphology seen in the disorder. The phenotype of each individual woman with PCOS can vary widely as can her metabolic risk. METHODS: This is a cross-sectional study of patients seen in a multidisciplinary PCOS clinic at the University of California at San Francisco between 2006 and 2014...
2017: Fertility Research and Practice
https://www.readbyqxmd.com/read/28620353/the-distribution-of-stroma-and-antral-follicles-differs-between-insulin-resistance-and-hyperandrogenism-related-polycystic-ovarian-syndrome
#10
Carlo Alviggi, Alessandro Conforti, Pasquale De Rosa, Ida Strina, Stefano Palomba, Roberta Vallone, Salvatore Gizzo, Rosaria Borrelli, Claus Yding Andersen, Giuseppe De Placido, Stefano Guerriero
INTRODUCTION: Although insulin resistance plays an important pathogenetic role in polycystic ovary syndrome (PCOS), no correlation between ultrasound PCOS pattern and insulin resistance has yet been reported. The aim of this retrospective observational study was to assess whether the ovarian ultrasonographic parameter differed between PCOS women with insulin resistance and those with a hyperandrogenic profile. MATERIALS AND METHODS: Women who fulfilled the Rotterdam criteria for PCOS were retrospectively studied...
2017: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/28617821/supplementation-with-small-extracellular-vesicles-from-ovarian-follicular-fluid-during-in-vitro-production-modulates-bovine-embryo-development
#11
Juliano C da Silveira, Gabriella M Andrade, Maite Del Collado, Rafael V Sampaio, Juliano R Sangalli, Luciano A Silva, Fábio V L Pinaffi, Izabelle B Jardim, Marcelo C Cesar, Marcelo F G Nogueira, Aline S M Cesar, Luiz L Coutinho, Rinaldo W Pereira, Felipe Perecin, Flávio V Meirelles
Pregnancy success results from the interaction of multiple factors, among them are folliculogenesis and early embryonic development. Failure during these different processes can lead to difficulties in conception. Alternatives to overcome these problems are based on assisted reproductive techniques. Extracellular vesicles are cell-secreted vesicles present in different body fluids and contain bioactive materials, such as messenger RNA, microRNAs (miRNAs), and proteins. Thus, our hypothesis is that extracellular vesicles from follicular fluid from 3-6 mm ovarian follicles can modulate bovine embryo development in vitro...
2017: PloS One
https://www.readbyqxmd.com/read/28616051/omega-3-supplementation-effects-on-polycystic-ovary-syndrome-symptoms-and-metabolic-syndrome
#12
Behnaz Khani, Farahnaz Mardanian, Sajadeh Jafari Fesharaki
BACKGROUND: Polycystic ovary syndrome (PCOS) is the most common female endocrine disorder with unknown etiology and with different complications. The aim of this study was to evaluate the effect of omega-3 supplementation on PCOS symptoms and metabolic syndrome. MATERIALS AND METHODS: This double-blind clinical trial was performed in 2015 in Alzahra and Shahid Beheshti Hospitals, Isfahan, Iran, on 88 patients with PCOS. Intervention group took omega-3 supplements with dose of 2 g/day for 6 months (two capsules), but control group received two olive oil capsules...
2017: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://www.readbyqxmd.com/read/28610887/a-hormonal-cue-promotes-timely-follicle-cell-migration-by-modulating-transcription-profiles
#13
Lathiena Manning, Jinal Sheth, Stacey Bridges, Afsoon Saadin, Kamsi Odinammadu, Deborah Andrew, Susan Spencer, Denise Montell, Michelle Starz-Gaiano
Cell migration is essential during animal development. In the Drosophila ovary, the steroid hormone ecdysone coordinates nutrient sensing, growth, and the timing of morphogenesis events including border cell migration. To identify downstream effectors of ecdysone signaling, we profiled gene expression in wild-type follicle cells compared to cells expressing a dominant negative Ecdysone receptor or its coactivator Taiman. Of approximately 400 genes that showed differences in expression, we validated 16 candidate genes for expression in border and centripetal cells, and demonstrated that seven responded to ectopic ecdysone activation by changing their transcriptional levels...
June 10, 2017: Mechanisms of Development
https://www.readbyqxmd.com/read/28610678/anti-m%C3%A3-llerian-hormone-follicle-stimulating-hormone-antral-follicle-count-and-risk-of-menopause-within-5-years
#14
Catherine Kim, James C Slaughter, Erica T Wang, Duke Appiah, Pamela Schreiner, Benjamin Leader, Ronit Calderon-Margalit, Barbara Sternfeld, David Siscovick, Melissa Wellons
OBJECTIVE: To evaluate the ability of concentration of anti-Müllerian hormone (AMH), antral follicle count (AFC), and concentration of follicle stimulating hormone (FSH) to predict the onset of menopause. STUDY DESIGN: The Coronary Artery Risk Development in Young Adults Study (CARDIA) Women's Study was an ancillary study to CARDIA, a population-based study of adults aged 18-30 years followed for 3 decades. For this report, participants were women (n=426) who had attended the CARDIA year 15-16 (2000-2001) examination, had at least one ovary, were not pregnant, and underwent serum AMH and FSH measurement and transvaginal ultrasonography in 2002-2003...
August 2017: Maturitas
https://www.readbyqxmd.com/read/28608837/hochu-ekki-to-treatment-improves-reproductive-and-immune-modulation-in-the-stress-induced-rat-model-of-polycystic-ovarian-syndrome
#15
Eunkuk Park, Chun Whan Choi, Soo Jeong Kim, Yong-In Kim, Samkee Sin, Jong-Phil Chu, Jun Young Heo
The traditional herbal medicine, Hochu-ekki-to, has been shown to have preventive effects on viral infection and stress. This study aimed to evaluate the clinical effects of Hochu-ekki-to on two stress-related rat models of polycystic ovarian syndrome. Female Sprague-Dawley rats were divided into control and treatment groups, the latter of which were subjected to stress induced by exposure to adrenocorticotropic hormone (ACTH) or cold temperatures. After these stress inductions, rats were orally treated with dissolved Hochu-ekki-to once per day for 7 days...
June 13, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28607932/the-protective-effect-of-n-acetylcysteine-on-ionizing-radiation-induced-ovarian-failure-and-loss-of-ovarian-reserve-in-female-mouse
#16
Wei Gao, Jin-Xiao Liang, Chi Ma, Jing-Yin Dong, Qiu Yan
Ionizing radiation may cause irreversible ovarian failure, which, therefore, calls for an effective radioprotective reagent. The aim of the present study was to evaluate the potential radioprotective effect of N-acetylcysteine (NAC) on ionizing radiation induced ovarian failure and loss of ovarian reserve in mice. Kun-Ming mice were either exposed to X-irradiation (4 Gy), once, and/or treated with NAC (300 mg/kg), once daily for 7 days before X-irradiation. We examined the serum circulating hormone levels and the development of ovarian follicles as well as apoptosis, cell proliferation, and oxidative stress 24 hours after X-irradiation...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28606727/expression-patterns-of-p38%C3%AE-mapk-during-follicular-development-in-the-ovaries-of-neonatal-rats
#17
Shifu Hu, Meng Rao, Hui Lei, Yanqing Wu, Yingying Wang, Dandan Ke, Wei Xia, Changhong Zhu
The p38αMAPK signaling pathway plays a critical role in female reproduction, but an understanding of its expression in rats remains elusive. This study was carried out to investigate the temporal and spatial expression of p38αMAPK and p-p38αMAPK. Ovarian tissue samples were collected from 2-, 4-, 8-, 12-, 16-, 20- and 30-day-old female rats. Western blotting was used to examine the relative expression of p38αMAPK and p-p38αMAPK in ovarian tissue, and subcellular localization was examined using immunohistochemistry of the rat ovaries at different ages of postpartum...
June 10, 2017: Acta Histochemica
https://www.readbyqxmd.com/read/28604799/rhythmic-expression-of-circadian-clock-genes-in-the-preovulatory-ovarian-follicles-of-the-laying-hen
#18
Zhichao Zhang, Shuang Lai, Yagang Wang, Liang Li, Huadong Yin, Yan Wang, Xiaoling Zhao, Diyan Li, Mingyao Yang, Qing Zhu
The circadian clock is reported to play a role in the ovaries in a variety of vertebrate species, including the domestic hen. However, the ovary is an organ that changes daily, and the laying hen maintains a strict follicular hierarchy. The aim of this study was to examine the spatial-temporal expression of several known canonical clock genes in the granulosa and theca layers of six hierarchy follicles. We demonstrated that the granulosa cells (GCs) of the F1-F3 follicles harbored intrinsic oscillatory mechanisms in vivo...
2017: PloS One
https://www.readbyqxmd.com/read/28601152/identification-and-expression-of-x-linked-inhibitor-of-apoptosis-protein-during-follicular-development-in-goat-ovary
#19
Peng Han, Haiyun Xin, Jiayin Peng, Jinxing Hou, Lei Zhang, Yuxuan Song, Guang Li, Binyun Cao, Xiaopeng An
X-linked inhibitor of apoptosis protein (XIAP), an endogenous of inhibitor of caspases, plays crucial roles in regulating ovarian granulosa cell apoptosis during follicular atresia. The aim of the present study was to determine the presence and localization of XIAP in the goat ovary and its expression level during follicular development. The full length cDNA of XIAP from goat ovary cells was cloned using reverse transcription PCR. A total of 497 amino acid residues were encoded by open reading frame and had high identity with homologous sequences from other mammals...
August 2017: Theriogenology
https://www.readbyqxmd.com/read/28598116/-optimal-ovulation-induction-in-polycystic-ovary-syndrome-resistant-to-clomiphene-citrate-or-letrozole
#20
Ying Chen, Dan Zhang
OBJECTIVES: To investigate the optimal ovulation induction with the combination of combining letrozole(LE),clomiphene citrate (CC),and human menopausal gonadotropin (HMG) in polycystic ovary syndrome(PCOS) patients resistant to CC or LE. METHODS: Two hundreds nine PCOS patients (209 cycles) resistant to CC or LE were randomly divided into three groups: CC+HMG group (59 cycles),LE+HMG group (72 cycles) and LE+CC group (78 cycles).The patients in LE+CC group unable to form the dominant follicle after 54 cycles were enrolled into LE+CC+HMG group...
November 2016: Sichuan da Xue Xue Bao. Yi Xue Ban, Journal of Sichuan University. Medical Science Edition
keyword
keyword
119256
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"