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https://www.readbyqxmd.com/read/27919312/lessons-from-an-outbreak-of-legionnaires-disease-on-a-hematology-oncology-unit
#1
Louise K Francois Watkins, Karrie-Ann E Toews, Aaron M Harris, Sherri Davidson, Stephanie Ayers-Millsap, Claressa E Lucas, Brian C Hubbard, Natalia A Kozak-Muiznieks, Edward Khan, Preeta K Kutty
OBJECTIVES To define the scope of an outbreak of Legionnaires' disease (LD), to identify the source, and to stop transmission. DESIGN AND SETTING Epidemiologic investigation of an LD outbreak among patients and a visitor exposed to a newly constructed hematology-oncology unit. METHODS An LD case was defined as radiographically confirmed pneumonia in a person with positive urinary antigen testing and/or respiratory culture for Legionella and exposure to the hematology-oncology unit after February 20, 2014. Cases were classified as definitely or probably healthcare-associated based on whether they were exposed to the unit for all or part of the incubation period (2-10 days)...
December 6, 2016: Infection Control and Hospital Epidemiology
https://www.readbyqxmd.com/read/27918255/outbreak-of-enterovirus-d68-of-the-new-b3-lineage-in-stockholm-sweden-august-to-september-2016
#2
Robert Dyrdak, Malin Grabbe, Berit Hammas, Jonas Ekwall, Karin E Hansson, Joachim Luthander, Pontus Naucler, Henrik Reinius, Maria Rotzén-Östlund, Jan Albert
We report an enterovirus D68 (EV-D68) outbreak in Stockholm Sweden in 2016. Between 22 August and 25 September EV-D68 was detected in 74/495 respiratory samples analysed at the Karolinska University Hospital. During the peak week, 30/91 (33%) samples were EV-D68 positive. Viral protein (VP)P4/VP2 sequencing revealed that cases were caused by B3 lineage strains. Forty-four (59%) EV-D68-positive patients were children aged ≤ 5 years. Ten patients had severe respiratory or neurological symptoms and one died...
November 17, 2016: Euro Surveillance: Bulletin Européen sur les Maladies Transmissibles, European Communicable Disease Bulletin
https://www.readbyqxmd.com/read/27905629/-reasons-to-recommend-vaccination-against-dengue-in-easter-island-immunization-advisory-committee-of-sociedad-chilena-de-infectolog%C3%A3-a
#3
Alberto Fica, Marcela Potin, Gabriela Moreno, Liliana Véliz, Jaime Cerda, Carola Escobar, Jan Wilhelm
Dengue was first diagnosed on Easter Island on year 2002 and thereafter recurrent outbreaks have occurred involving different serotypes of dengue virus. Its vector, Aedes aegypti has not been eliminated despite the small size of the island. Conditions at the local hospital preclude adequate management of severe and hemorrhagic cases due to the absence of a Critical Care Unit as well as no availability of platelets, or plasma units for transfusion. Besides, transfer, of severely affected patients to continental Chile is cumbersome, slow and expensive...
August 2016: Revista Chilena de Infectología: órgano Oficial de la Sociedad Chilena de Infectología
https://www.readbyqxmd.com/read/27905620/-the-water-supply-of-a-pediatric-hospital-as-a-possible-source-of-an-outbreak-of-diarrhea-due-to-microsporidium-spp-in-immunocompromised-patients
#4
Paulina Coria, Claudia Urízar, Andrea Alba, Isabel Noemí, Anita Pino, José Luis Cerva
INTRODUCTION: The hospital water supply is a reservoir of a variety of potentially pathogenic microorganisms that can particularly affect children and immunocompromised patients. Potentially pathogenic Microsporidium spp. have been identified in water. Microsporidiosis is an emerging parasitic and opportunistic infection in immunocompromised patients. OBJECTIVE AND METHOD: to describe an outbreak of nosocomial diarrhea due to Microsporidium, species Encephalitozoon intestinalis...
August 2016: Revista Chilena de Infectología: órgano Oficial de la Sociedad Chilena de Infectología
https://www.readbyqxmd.com/read/27905271/the-effects-of-climate-factors-on-scabies-a-14-year-population-based-study-in-taiwan
#5
Jui-Ming Liu, Hsiao-Wei Wang, Fung-Wei Chang, Yueh-Ping Liu, Feng-Hsiang Chiu, Yi-Chun Lin, Kuan-Chen Cheng, Ren-Jun Hsu
Scabies is a common infectious disease and can cause severe outbreaks if not controlled quickly. Besides personal contact history, environmental factors are also important. This study analyzed the effects of environmental climate factors on the incidence of scabies in Taiwan. We conducted a 14-year nationwide population-based study: a total of 14,883 patients with scabies infestation were enrolled. Monthly climate data were collected from Taiwan's Central Weather Bureau, including data on temperature, relative humidity, total rainfall, total rain days, and total sunshine hours...
2016: Parasite: Journal de la Société Française de Parasitologie
https://www.readbyqxmd.com/read/27904748/patterns-of-medication-use-and-factors-associated-with-antibiotic-use-among-adult-fever-patients-at-singapore-primary-care-clinics
#6
Zaw Myo Tun, Mahesh Moorthy, Martin Linster, Yvonne C F Su, Richard James Coker, Eng Eong Ooi, Jenny Guek-Hong Low, Gavin J D Smith, Clarence C Tam
BACKGROUND: Antimicrobial resistance is a public health problem of global importance. In Singapore, much focus has been given to antibiotic usage patterns in hospital settings. Data on antibiotic use in primary care is lacking. We describe antibiotic usage patterns and assess factors contributing to antibiotic usage among adults presenting with acute febrile illness (AFI) in primary care settings in Singapore. METHODS: We analyzed data from the Early Dengue infection and outcome study...
2016: Antimicrobial Resistance and Infection Control
https://www.readbyqxmd.com/read/27902502/zika-virus-and-patient-blood-management
#7
Lawrence T Goodnough, Marisa B Marques
Sporadic Zika virus infections had only occurred in Africa and Asia until an outbreak in Micronesia (Oceania) in 2007. In 2013 to 2014, several outer Pacific Islands reported local outbreaks. Soon thereafter, the virus was likely introduced in Brazil from competing athletes from French Polynesia and other countries that participated in a competition there. Transmission is thought to have occurred through mosquito bites and spread to the immunologically naive population. Being also a flavivirus, the Zika virus is transmitted by the Aedes mosquito that is endemic in South and Central America that is also the vector of West Nile virus, dengue, and chikungunya...
November 29, 2016: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/27900923/-the-infection-risk-scan-in-clinical-practice-improving-infection-prevention-and-antibiotic-use-through-transparency
#8
I Willemsen, J A J W Kluytmans
OBJECTIVE: The increase in Highly Resistant Micro-Organisms (HRMO) in hospitals and nursing homes requires an intensification of infection prevention measures. This paper describes a new, standardised approach to infection prevention and monitoring of antibiotic use. DESIGN: Cross-sectional, observational study. METHOD: The Infection RIsk Scan (IRIS) measures a number of objectifiable variables in the field of infection prevention, including the dissemination of HRMO, the use of antibiotics and indwelling medical devices, environmental contamination, hand hygiene and personal hygiene of healthcare workers, and various infection control preconditions...
2016: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/27891060/human-metapneumovirus-in-the-preterm-neonate-current-perspectives
#9
Nathalie L Maitre, John V Williams
Premature birth (<37 weeks gestation) occurs in ~11% of all births in the US. These infants are at risk of chronic lung disease and respiratory conditions, including bronchopulmonary dysplasia. Respiratory viruses are important causes of acute respiratory illness (ARI) in preterm infants, leading to rehospitalization, increased health care burden, and long-term morbidity. Human metapneumovirus (HMPV) is a paramyxovirus discovered in 2001 that is related to respiratory syncytial virus. Epidemiologic studies show that HMPV is a leading cause of ARI in children and adults worldwide...
2016: Research and Reports in Neonatology
https://www.readbyqxmd.com/read/27890334/control-of-carbapenemase-producing-enterobacteriaceae-outbreaks-in-acute-settings-an-evidence-review
#10
REVIEW
C E French, C Coope, L Conway, J P T Higgins, J McCulloch, G Okoli, B C Patel, I Oliver
BACKGROUND: In recent years, infections with carbapenemase-producing Enterobacteriaceae (CPE) have been increasing globally and present a major public health challenge. AIM: To review the international literature: (i) to describe CPE outbreaks in acute hospital settings globally; and (ii) to identify the control measures used during these outbreaks and report on their effectiveness. METHODS: A systematic search of MEDLINE and EMBASE databases, abstract lists for key conferences and reference lists of key reviews was undertaken, and information on unpublished outbreaks was sought for 2000-2015...
October 14, 2016: Journal of Hospital Infection
https://www.readbyqxmd.com/read/27881617/can-a-multi-drug-resistant-candida-auris-be-reliably-identified-in-clinical-microbiology-laboratories
#11
Masako Mizusawa, Heather Miller, Rachel Green, Richard Lee, Mariann Durante, Rosalie Perkins, Caroline Hewitt, Patricia J Simner, Karen C Carroll, Randall T Hayden, Sean X Zhang
Candida auris, an emerging multi-drug resistant yeast associated with high mortality, has been increasingly reported from outside of the US to cause outbreaks in the hospital settings (1).….
November 23, 2016: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/27880750/notes-from-the-field-clostridium-perfringens-gastroenteritis-outbreak-associated-with-a-catered-lunch-north-carolina-november-2015
#12
Jessica L Rinsky, E Berl, V Greene, J Morrow, A Didomenico, J MacFarquhar, G A Gómez, C Lúquez, C Williams
During November 2015, the North Carolina Division of Public Health was notified by the Pitt County Health Department (PCHD) that approximately 40 persons who attended a catered company Thanksgiving lunch the previous day were ill with diarrhea and abdominal pain. The North Carolina Division of Public Health and PCHD worked together to investigate the source of illness and implement control measures. Within hours of notification, investigators developed and distributed an online survey to all lunch attendees regarding symptoms and foods consumed and initiated a cohort study...
November 25, 2016: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/27876594/successful-control-of-a-large-outbreak-of-hiv-infection-associated-with-injection-of-cathinone-derivatives-in-tel-aviv-israel
#13
Eugene Katchman, Ronen Ben-Ami, Michal Savyon, Daniel Chemtob, Boaz Avidor, Asaf Wasserman, Irena Zeldis, Shirley Girshengorn, Ziva Amitai, Rivka Sheffer, Dan Turner
OBJECTIVES: Outbreaks of HIV infection have been linked to injectable drug abuse, but specific triggers often remain obscure. We report on an outbreak of primary HIV infection among people who inject drugs (PWID) in Tel Aviv, associated with a local shift in drug-use practices. METHODS: A cluster of primary HIV infection cases in PWID was detected in May 2012. Retrospective and prospective multi-hospital case finding was initiated. PWID were interviewed and risk factors for primary HIV infection were identified...
November 19, 2016: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/27875593/enterovirus-d68-in-hospitalized-children-sequence-variation-viral-loads-and-clinical-outcomes
#14
Katherine Moyer, Huanyu Wang, Douglas Salamon, Amy Leber, Asuncion Mejias
BACKGROUND: An outbreak of enterovirus D68 (EV-D68) caused severe respiratory illness in 2014. The disease spectrum of EV-D68 infections in children with underlying medical conditions other than asthma, the role of EV-D68 loads on clinical illness, and the variation of EV-D68 strains within the same institution over time have not been described. We sought to define the association between EV-D68 loads and sequence variation, and the clinical characteristic in hospitalized children at our institution from 2011 to 2014...
2016: PloS One
https://www.readbyqxmd.com/read/27870538/foodborne-infections-and-intoxications-in-poland-in-2014
#15
Piotr Polański, Sylwia Kamińska, Małgorzata Sadkowska-Todys
AIM: The purpose of the study is to assess the epidemiological situation of food poisonings and infections in Poland in 2014. MATERIALS AND METHODS: The evaluation was based on the analysis of information sent to Department of Epidemiology NIPH-NIH through ROE (Pol. Rejestr Ognisk Epidemicznych)- an electronic system created for uploading, transfer and analysis of data acquired during the outbreak investigations). Additional sources for the analysis were NIZP-PZH annual bulletins (Czarkowski MP et al...
2016: Przegla̧d Epidemiologiczny
https://www.readbyqxmd.com/read/27869401/yersiniosis-in-poland-in-2014
#16
Sylwia Kamińska, Małgorzata Sadkowska-Todys
OBJECTIVE: The aim of the study is to present the epidemiological situation of yersiniosis in Poland in 2014 and compare it with the situation in the previous years. MATERIAL AND METHODS: The evaluation was based on analysis of data from the annual bulletins “Infectious diseases and poisoning in Poland” for the period 2009-2014 (MP Czarkowski et al., National Institute of Hygiene and GIS – Chief Sanitary Inspectorate), interviews of individual yersiniosis cases, sent by the sanitary-epidemiological stations from the whole country and the data on deaths from the Department of Demographic Studies of the Central Statistical Office...
2016: Przegla̧d Epidemiologiczny
https://www.readbyqxmd.com/read/27867062/evaluation-of-convalescent-whole-blood-for-treating-ebola-virus-disease-in-freetown-sierra-leone
#17
F Sahr, R Ansumana, T A Massaquoi, B R Idriss, F R Sesay, J M Lamin, S Baker, S Nicol, B Conton, W Johnson, O T Abiri, O Kargbo, P Kamara, A Goba, J B W Russell, S M Gevao
BACKGROUND: Convalescent blood therapy has been a promising form of treatment for Ebola Virus Disease (EVD), but less attention has been focused on it for treatment. METHOD: We assessed the effectiveness of convalescent whole blood (CWB) in the treatment of consented EVD patients. We recruited 69 subjects in December 2014 up to April 2015, at the 34 Military Hospital in Wilberforce and the PTS 1 Ebola Treatment Unit in Hastings, Freetown. Forty-four were given CWB, and 25 who consented but preferred to be exempted from the CWB treatment were used to compare clinical outcomes...
November 17, 2016: Journal of Infection
https://www.readbyqxmd.com/read/27865634/molecular-epidemiology-and-spatiotemporal-analysis-of-hospital-acquired-acinetobacter-baumannii-infection-in-a-tertiary-care-hospital-in-southern-thailand
#18
S Chusri, V Chongsuvivatwong, J I Rivera, K Silpapojakul, K Singkhamanan, E McNeil, Y Doi
BACKGROUND: Acinetobacter baumannii is a major hospital-acquired pathogen in Thailand that has a negative effect on patient survival. The nature of its transmission is poorly understood. AIM: To investigate the genotypic and spatiotemporal pattern of A. baumannii infection at a hospital in Thailand. METHODS: The medical records of patients infected with A. baumannii at an 800-bed tertiary care hospital in southern Thailand between January 2010 and December 2011 were reviewed retrospectively...
October 22, 2016: Journal of Hospital Infection
https://www.readbyqxmd.com/read/27865096/salmonellosis-in-poland-in-2014
#19
Małgorzata Sadkowska-Todys, Mirosław P Czarkowski
OBJECTIVE: The aim of the study is to assess the epidemiological situation of salmonellosis in Poland in 2014 in comparison to the previous years. MATERIAL AND METHODS: The evaluation was based on the data from the bulletin “Infectious diseases and poisoning in Poland 2014”, information from the laboratories of sanitary-epidemiological stations and reports from the epidemiological investigations in outbreaks of salmonellosis, sent by the sanitary-epidemiological stations to the Department of Epidemiology, as well as the data from the Department of Demographic Studies of the Central Statistical Office...
2016: Przegla̧d Epidemiologiczny
https://www.readbyqxmd.com/read/27863959/transmission-of-staphylococcus-aureus-between-health-care-workers-the-environment-and-patients-in-an-intensive-care-unit-a-longitudinal-cohort-study-based-on-whole-genome-sequencing
#20
James R Price, Kevin Cole, Andrew Bexley, Vasiliki Kostiou, David W Eyre, Tanya Golubchik, Daniel J Wilson, Derrick W Crook, A Sarah Walker, Timothy E A Peto, Martin J Llewelyn, John Paul
BACKGROUND: Health-care workers have been implicated in nosocomial outbreaks of Staphylococcus aureus, but the dearth of evidence from non-outbreak situations means that routine health-care worker screening and S aureus eradication are controversial. We aimed to determine how often S aureus is transmitted from health-care workers or the environment to patients in an intensive care unit (ICU) and a high-dependency unit (HDU) where standard infection control measures were in place. METHODS: In this longitudinal cohort study, we systematically sampled health-care workers, the environment, and patients over 14 months at the ICU and HDU of the Royal Sussex County Hospital, Brighton, England...
November 15, 2016: Lancet Infectious Diseases
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