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https://www.readbyqxmd.com/read/29165513/-a-five-year-experience-with-zoonotic-salmonella-at-a-pediatric-reference-centre
#1
Patricia Barrios, Federica Badía, Valentina Misa, M Inés Mota, Arací Martínez, Hebert Mariño, Gabriela Algorta, Javier Prego, M Catalina Pírez
BACKGROUND: Salmonella can cause asymptomatic infections, diarrhea, bacteremia and focal infections such as meningitis and osteomyelitis. AIM: To describe clinical and microbiological aspects of infections by Salmonella spp. in children in a pediatric referral hospital: Centro Hospitalario Pereira Rossell, in Montevideo, Uruguay. MATERIALS AND METHODS: Descriptive and retrospective study of 46 patients, from which Salmonella spp was isolated between January 1, 2005 and December 31, 2010...
August 2017: Revista Chilena de Infectología: órgano Oficial de la Sociedad Chilena de Infectología
https://www.readbyqxmd.com/read/29163416/diagnostic-evasion-of-highly-resistant-microorganisms-a-critical-factor-in-nosocomial-outbreaks
#2
Xuewei Zhou, Alexander W Friedrich, Erik Bathoorn
Highly resistant microorganisms (HRMOs) may evade screening strategies used in routine diagnostics. Bacteria that have evolved to evade diagnostic tests may have a selective advantage in the nosocomial environment. Evasion of resistance detection can result from the following mechanisms: low-level expression of resistance genes not resulting in detectable resistance, slow growing variants, mimicry of wild-type-resistance, and resistance mechanisms that are only detected if induced by antibiotic pressure. We reviewed reports on hospital outbreaks in the Netherlands over the past 5 years...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29162493/outbreak-of-gentamicin-resistant-meticillin-susceptible-staphlococcus-aureus-on-a-neonatal-unit
#3
Sahar Eldirdiri, Jennifer Lee, Ann Jack, Alison Wright, Alison Findlay, Gabby Phillips
BACKGROUND: This report describes an outbreak of gentamicin-resistant meticillin-resistant Staphylococcus aureus (GR MSSA) which occurred on a 21-bed neonatal unit (NNU) in Ninewells Hospital, Dundee, Scotland. METHODS: An outbreak investigation was triggered by two new GR MSSA isolates from babies admitted directly to the unit who had acquired this organism during their stay. Data on MSSA cases and antibiograms of patient isolates were flagged as an alert and microbiology records trawled to detect previous cases...
November 18, 2017: Journal of Hospital Infection
https://www.readbyqxmd.com/read/29162354/-cryptosporidiosis-a-cause-of-acute-diarrhea-a-review-and-retrospective-study-of-cases-in-rouen-university-hospital-s-pediatrics-department
#4
G Gargala, R Razakandrainibe, D Costa, D Leméteil, C Dumant Forest
Cryptosporidium is the most important diarrhea-causing protozoan parasite, with severe health consequences for very young, malnourished children living in endemic areas and for immunocompromised individuals. Cryptosporidium is widely distributed and disease transmission can occur through person-to-person or animal-to-person contact, or contaminated food or water (drinking or swimming), leading to large outbreaks. The zoonotic Cryptosporidium parvum and the anthroponotic Cryptosporidium hominis are responsible for the majority of human cases...
November 18, 2017: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
https://www.readbyqxmd.com/read/29161992/stenotrophomonas-maltophilia-causing-blood-stream-infection-in-neonates-and-infants-a-cause-for-concern
#5
Rinku Sah, Shraddha Siwakoti, Ratna Baral, Rupa S Rajbhandari, Basuda Khanal
Stenotrophomonas maltophilia ( S. maltophilia) is an important Gram-negative, non-fermentative, multidrug resistant (MDR) nosocomial organism. We evaluated the isolation of S. maltophilia from the seven blood culture specimens received from the Paediatric Emergency Department (PED) of BP Koirala Institute of Health Sciences (BPKIHS) over the duration of two weeks. The suspicion of a possible outbreak was raised and the hospital infection control team investigated the source and found the hand of one healthcare provider harbouring a similar organism...
January 1, 2017: Tropical Doctor
https://www.readbyqxmd.com/read/29161394/managing-anaesthetic-provision-for-global-disasters
#6
R M Craven
The numbers of people affected by large-scale disasters has increased in recent decades. Disasters produce a huge burden of surgical morbidity at a time when the affected country is least able to respond. For this reason an international disaster response is often required. For many years this disaster response was not coordinated. The response consisted of what was available not what was needed and standards of care varied widely producing a healthcare lottery for the affected population. In recent years the World Health organisation has initiated the Emergency Medical Team programme to coordinate the response to disasters and set minimum standards for responding teams...
December 1, 2017: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/29158907/chikungunya-outbreak-in-delhi-india-2016-report-on-coinfection-status-and-comorbid-conditions-in-patients
#7
N Kaur, J Jain, A Kumar, M Narang, M K Zakaria, A Marcello, D Kumar, R Gaind, S Sunil
Chikungunya fever is a major public health issue in India affecting billions. After 2010, the infection was in a decline until in 2016, when a massive outbreak affected the country. In this report, we present serologic and molecular investigations of 600 patient samples for chikungunya and dengue viruses along with clinical and comorbidity features. We recruited 600 patients during this outbreak and evaluated them for chikungunya and dengue virus antibodies and virus RNA through IgM, NS1 antigen and quantitative real-time PCR (qPCR)...
November 2017: New Microbes and New Infections
https://www.readbyqxmd.com/read/29158893/evaluation-of-a-stenotrophomonas-maltophilia-bacteremia-cluster-in-hematopoietic-stem-cell-transplantation-recipients-using-whole-genome-sequencing
#8
Stefanie Kampmeier, Mike H Pillukat, Aleksandra Pettke, Annelene Kossow, Evgeny A Idelevich, Alexander Mellmann
Background: Stenotrophomonas maltophilia ubiquitously occurs in the hospital environment. This opportunistic pathogen can cause severe infections in immunocompromised hosts such as hematopoietic stem cell transplantation (HSCT) recipients. Between February and July 2016, a cluster of four patients on the HSCT unit suffered from S. maltophilia bloodstream infections (BSI). Methods: For epidemiological investigation we retrospectively identified the colonization status of patients admitted to the ward during this time period and performed environmental monitoring of shower heads, shower outlets, washbasins and toilets in patient rooms...
2017: Antimicrobial Resistance and Infection Control
https://www.readbyqxmd.com/read/29157211/alkaline-peptone-water-enrichment-with-a-dipstick-test-to-quickly-detect-and-monitor-cholera-outbreaks
#9
Godfrey Bwire, Christopher Garimoi Orach, Dauda Abdallah, Amanda Kay Debes, Atek Kagirita, Malathi Ram, David A Sack
BACKGROUND: Detection, confirmation and monitoring of cholera outbreaks in many developing countries including Uganda is a big challenge due to lack of the required resources and the time the test takes. Culture method which takes 24-48 h to get the feedback and requires highly skilled laboratory staff plus other complex resources is the standard test. This study evaluated the new cholera rapid detection method that relies on Crystal VC dipsticks after enrichment with alkaline peptone water (APW) against the culture method for monitoring the progress of cholera outbreaks in rural setting...
November 21, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29148876/food-safety-at-farmers-markets-a-knowledge-synthesis-of-published-research
#10
Ian Young, Abhinand Thaivalappil, Danielle Reimer, Judy Greig
Farmers' markets are increasingly popular venues in North America for the sale of fresh produce and other foods. However, the nature of their operation can present possible food safety issues, challenges, and risks to consumers. A knowledge synthesis was conducted to identify, characterize, and summarize published research on the microbial food safety issues and implications associated with farmers' markets. A scoping review was conducted using the following steps: comprehensive search strategy, relevance screening of abstracts, and characterization of relevant articles...
November 17, 2017: Journal of Food Protection
https://www.readbyqxmd.com/read/29147867/population-structure-of-candida-parapsilosis-no-genetic-difference-between-french-and-urugayan-isolates-using-microsatellite-length-polymorphism
#11
Marie Desnos-Ollivier, Victoria Bórmida, Philippe Poirier, Céline Nourrisson, Dinorah Pan, Stéphane Bretagne, Andrès Puime, Françoise Dromer
Candida parapsilosis is a human commensal yeast, frequently involved in infection worldwide and especially in neonates. It is the second species responsible for bloodstream infections in Uruguay and the third species in France. We were interested in knowing whether the population structure of isolates responsible for candidemia in France and in Uruguay was different. Genotyping methods based on microsatellite length polymorphism (MLP) have been described and are especially used for investigation of local outbreaks...
November 16, 2017: Mycopathologia
https://www.readbyqxmd.com/read/29147641/severity-of-acute-zika-virus-infection-a-prospective-emergency-room-surveillance-study-during-the-2015-2016-outbreak-in-suriname
#12
Pieter Vroon, Jimmy Roosblad, Fauzia Poese, Jan Wilschut, John Codrington, Stephen Vreden, Rens Zonneveld
Acute Zika virus (ZIKV) infection is usually mild and self-limiting. Earlier, we reported three cases of fatal acute ZIKV infection in patients without typical signs of ZIKV, but rather with criteria of systemic inflammation response syndrome (SIRS). To follow up these observations, we prospectively included patients at the emergency room with temperature instability and suspected to have acute ZIKV infection, SIRS, or both. A total of 102 patients were included of whom N = 21 (21%) were suspected of acute ZIKV infection, N = 56 (55%) of acute ZIKV infection with SIRS criteria, and N = 25 (24%) of SIRS alone...
2017: IDCases
https://www.readbyqxmd.com/read/29141401/-simulation-of-an-outbreak-of-acinetobacter-baumannii-in-hospitals
#13
A Martín-Del Rey, M García-Moro, E García-Sánchez, E García-Merino, J E García-Sánchez
OBJECTIVE: Acinetobacter baumannii infections have increased over time becoming a significant issue. Consequently, those applications that allow to predict the evolution of an outbreak and the relevance of the different control methods, are very important. The design of mathematical models plays a central role in this topic. METHODS: Development of a deterministic mathematical model based on ordinary differential equations whose variables and parameters are defined upon the basis of knowledge of the epidemiology and characteristics of A...
November 13, 2017: Revista Española de Quimioterapia: Publicación Oficial de la Sociedad Española de Quimioterapia
https://www.readbyqxmd.com/read/29141051/molecular-and-epidemiological-characterization-of-carbapenemase-producing-enterobacteriaceae-in-norway-2007-to-2014
#14
Ørjan Samuelsen, Søren Overballe-Petersen, Jørgen Vildershøj Bjørnholt, Sylvain Brisse, Michel Doumith, Neil Woodford, Katie L Hopkins, Bettina Aasnæs, Bjørg Haldorsen, Arnfinn Sundsfjord
The prevalence of carbapenemase-producing Enterobacteriaceae (CPE) is increasing worldwide. Here we present associated patient data and molecular, epidemiological and phenotypic characteristics of all CPE isolates in Norway from 2007 to 2014 confirmed at the Norwegian National Advisory Unit on Detection of Antimicrobial Resistance. All confirmed CPE isolates were characterized pheno- and genotypically, including by whole genome sequencing (WGS). Patient data were reviewed retrospectively. In total 59 CPE isolates were identified from 53 patients...
2017: PloS One
https://www.readbyqxmd.com/read/29141023/domestic-sheep-show-average-coxiella-burnetii-seropositivity-generations-after-a-sheep-associated-human-q-fever-outbreak-and-lack-detectable-shedding-by-placental-vaginal-and-fecal-routes
#15
Ryan D Oliveira, Michelle R Mousel, Kristy L Pabilonia, Margaret A Highland, J Bret Taylor, Donald P Knowles, Stephen N White
Coxiella burnetii is a globally distributed zoonotic bacterial pathogen that causes abortions in ruminant livestock. In humans, an influenza-like illness results with the potential for hospitalization, chronic infection, abortion, and fatal endocarditis. Ruminant livestock, particularly small ruminants, are hypothesized to be the primary transmission source to humans. A recent Netherlands outbreak from 2007-2010 traced to dairy goats resulted in over 4,100 human cases with estimated costs of more than 300 million euros...
2017: PloS One
https://www.readbyqxmd.com/read/29140769/addressing-maternal-health-during-cdc-s-ebola-response-in-the-united-states
#16
Sascha Ellington, Mirna Perez, Diane Morof, Marianne E Zotti, William Callaghan, Dana Meaney-Delman, Maleeka Glover, Quynh-Chau Ha, Denise J Jamieson
Previous outbreaks suggest that pregnant women with Ebola virus disease (EVD) are at increased risk for severe disease and death. Healthcare workers who treat pregnant women with EVD are at increased risk of body fluid exposure. Despite the absence of pregnant women with EVD in the United States, CDC activated the Maternal Health Team (MHT), a functional unit dedicated to emergency preparedness and response issues, on October 18, 2014. We describe major activities of the MHT. A high-priority MHT activity was to publish guiding principles early in the response...
November 2017: Journal of Women's Health
https://www.readbyqxmd.com/read/29132042/long-range-interactions-keep-bacterial-cells-from-liquid-solid-interfaces-evidence-of-a-bacteria-exclusion-zone-near-nafion-surfaces-and-possible-implications-for-bacterial-attachment
#17
Yifan Cheng, Carmen I Moraru
Hydrophilic surfaces of both abiotic and biological origin have been shown to bear particle-exclusion zones as large as hundreds of micrometers at liquid-solid interfaces. Here we present the first systematic investigation and evidence for bacteria-free exclusion zones for several bacterial strains, including pathogens associated with hospital infections and/or foodborne outbreaks: Staphylococcus aureus, Escherichia coli O157:H7, and Listeria monocytogenes. Tests were carried out both in a phosphate buffer, as well as triptic soy broth (TSB) of high ionic strength...
November 10, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/29128948/a-dramatic-case-of-odynophagia
#18
B Sopeña, J Limeres, L García-Caballero, M Diniz-Freitas, J Seoane, P Diz
We report the case of a 77-year-old male with a history of aortic stenosis and interstitial lung disease, who debuted 3 years ago with an outbreak of necrotic and very painful canker sores. The severity of the lesions and their refractory response to treatment led to several hospital admissions and multiple consultations to different specialists (ENT, rheumatology, dermatology, ophthalmology, cardiology, and internal medicine). During this time, the patient received central parenteral nutrition with an episode of catheter-related septicemia, and he came to require psychiatric assistance for autolytic ideation...
November 11, 2017: Dysphagia
https://www.readbyqxmd.com/read/29126393/genomic-characterisation-of-clinical-and-environmental-pseudomonas-putida-group-strains-and-determination-of-their-role-in-the-transfer-of-antimicrobial-resistance-genes-to-pseudomonas-aeruginosa
#19
Silke Peter, Philipp Oberhettinger, Leonard Schuele, Ariane Dinkelacker, Wichard Vogel, Daniela Dörfel, Daniela Bezdan, Stephan Ossowski, Matthias Marschal, Jan Liese, Matthias Willmann
BACKGROUND: Pseudomonas putida is a Gram-negative, non-fermenting bacterium frequently encountered in various environmental niches. P. putida rarely causes disease in humans, though serious infections and outbreaks have been reported from time to time. Some have suggested that P. putida functions as an exchange platform for antibiotic resistance genes (ARG), and thus represents a serious concern in the spread of ARGs to more pathogenic organisms within a hospital. Though poorly understood, the frequency of ARG exchange between P...
November 10, 2017: BMC Genomics
https://www.readbyqxmd.com/read/29125713/outbreak-of-invasive-aspergillosis-in-heart-transplant-recipients-the-role-of-screening-computed-tomography-scans-in-asymptomatic-patients-and-universal-antifungal-prophylaxis
#20
Dima Kabbani, Livia Goldraich, Heather Ross, Coleman Rotstein, Shahid Husain
BACKGROUND: Delays in diagnosing invasive pulmonary aspergillosis (IA), a significant cause of morbidity and mortality among heart transplant recipients (HTRs), may impact on successful treatment. The appropriate screening strategy for IA in these patients remains undefined, particularly in the setting of nosocomial outbreaks. We describe our experience employing chest computed tomography (CT) scans as a screening method for IA. In addition, we comment on antimicrobial prophylaxis in HTRs in the setting of an outbreak...
November 10, 2017: Transplant Infectious Disease: An Official Journal of the Transplantation Society
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